Mus musculus

35 known processes

Map3k14

mitogen-activated protein kinase kinase kinase 14

(Aliases: Nik,aly)

Map3k14 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
lymph node development GO:0048535 18 1.000
positive regulation of translational initiation GO:0045948 4 1.000
positive regulation of chronic inflammatory response GO:0002678 4 1.000
positive regulation of translational initiation by iron GO:0045994 2 1.000
osteoclast proliferation GO:0002158 4 0.999
corticotropin releasing hormone secretion GO:0043396 2 0.999
somatic diversification of immunoglobulins involved in immune response GO:0002208 36 0.999
regulation of translational initiation by iron GO:0006447 2 0.998
necroptotic signaling pathway GO:0097527 3 0.998
lymphocyte differentiation GO:0030098 242 0.996
intrinsic apoptotic signaling pathway in response to dna damage GO:0008630 57 0.996
t cell differentiation GO:0030217 174 0.996
positive regulation of isotype switching to igg isotypes GO:0048304 7 0.995
regulation of b cell proliferation GO:0030888 39 0.994
positive regulation of myoblast differentiation GO:0045663 8 0.994
regulation of interleukin 6 production GO:0032675 55 0.994
extrinsic apoptotic signaling pathway GO:0097191 126 0.994
prostaglandin transport GO:0015732 7 0.993
t cell receptor signaling pathway GO:0050852 46 0.991
positive regulation of antibacterial peptide biosynthetic process GO:0006963 1 0.991
positive regulation of acute inflammatory response GO:0002675 16 0.991
heat generation GO:0031649 13 0.991
b cell activation involved in immune response GO:0002312 50 0.990
i kappab kinase nf kappab signaling GO:0007249 85 0.989
cellular response to molecule of bacterial origin GO:0071219 83 0.989
regulation of chronic inflammatory response to antigenic stimulus GO:0002874 3 0.989
antibacterial peptide production GO:0002778 2 0.988
regulation of translational initiation GO:0006446 15 0.987
fever generation GO:0001660 7 0.986
positive regulation of chronic inflammatory response to antigenic stimulus GO:0002876 2 0.985
somatic recombination of immunoglobulin genes involved in immune response GO:0002204 36 0.984
positive regulation of interleukin 12 production GO:0032735 21 0.984
myeloid cell differentiation GO:0030099 233 0.982
interleukin 10 secretion GO:0072608 4 0.982
positive regulation of cytokine production GO:0001819 174 0.980
engulfment of apoptotic cell GO:0043652 3 0.979
positive regulation of fever generation GO:0031622 6 0.977
regulation of fever generation by regulation of prostaglandin secretion GO:0071810 2 0.973
somatic recombination of immunoglobulin gene segments GO:0016447 42 0.972
regulation of inflammatory response to antigenic stimulus GO:0002861 21 0.971
humoral immune response GO:0006959 57 0.971
negative regulation of interleukin 5 production GO:0032714 4 0.970
immune response activating signal transduction GO:0002757 116 0.970
regulation of production of molecular mediator of immune response GO:0002700 65 0.970
t cell differentiation in thymus GO:0033077 77 0.968
antimicrobial peptide production GO:0002775 2 0.967
regulation of leukocyte proliferation GO:0070663 121 0.967
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 55 0.967
positive regulation of inflammatory response to antigenic stimulus GO:0002863 11 0.967
positive regulation of cd8 positive alpha beta t cell extravasation GO:2000451 2 0.967
regulation of cell activation GO:0050865 289 0.966
regulation of syncytium formation by plasma membrane fusion GO:0060142 23 0.964
regulation of corticotropin releasing hormone secretion GO:0043397 2 0.963
regulation of fever generation GO:0031620 6 0.963
positive regulation of cell activation GO:0050867 158 0.963
negative regulation of alkaline phosphatase activity GO:0010693 3 0.962
regulation of b cell activation GO:0050864 81 0.962
interferon gamma production GO:0032609 67 0.961
regulation of interleukin 5 secretion GO:2000662 2 0.961
inflammatory response to antigenic stimulus GO:0002437 30 0.960
positive regulation of osteoclast development GO:2001206 3 0.959
leukocyte differentiation GO:0002521 342 0.956
t cell activation GO:0042110 289 0.956
hair follicle development GO:0001942 85 0.956
somatic diversification of immunoglobulins GO:0016445 43 0.956
positive regulation of b cell proliferation GO:0030890 24 0.954
positive regulation of interferon gamma production GO:0032729 39 0.954
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 68 0.954
chronic inflammatory response GO:0002544 9 0.953
b cell activation GO:0042113 161 0.950
myeloid leukocyte differentiation GO:0002573 119 0.948
positive regulation of humoral immune response mediated by circulating immunoglobulin GO:0002925 6 0.948
regulation of acute inflammatory response GO:0002673 27 0.947
immunoglobulin mediated immune response GO:0016064 69 0.946
syncytium formation by plasma membrane fusion GO:0000768 42 0.944
tumor necrosis factor mediated signaling pathway GO:0033209 13 0.943
t cell migration GO:0072678 19 0.943
t cell chemotaxis GO:0010818 6 0.942
b cell differentiation GO:0030183 78 0.940
dendritic cell differentiation GO:0097028 26 0.939
tumor necrosis factor production GO:0032640 50 0.938
negative regulation of interleukin 10 secretion GO:2001180 2 0.938
lymphocyte proliferation GO:0046651 164 0.937
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 45 0.935
positive regulation of fever generation by positive regulation of prostaglandin secretion GO:0071812 2 0.935
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.933
regulation of icosanoid secretion GO:0032303 8 0.931
positive regulation of icosanoid secretion GO:0032305 7 0.930
regulation of cytokine production GO:0001817 266 0.929
immunoglobulin secretion GO:0048305 17 0.928
chronic inflammatory response to antigenic stimulus GO:0002439 3 0.925
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 61 0.924
positive regulation of leukocyte proliferation GO:0070665 73 0.924
positive regulation of adaptive immune response GO:0002821 61 0.923
cd4 positive cd25 positive alpha beta regulatory t cell differentiation GO:0002361 4 0.922
antibacterial humoral response GO:0019731 8 0.922
regulation of immunoglobulin mediated immune response GO:0002889 37 0.922
interleukin 12 production GO:0032615 32 0.917
negative regulation of interleukin 13 secretion GO:2000666 1 0.913
cellular response to amino acid stimulus GO:0071230 29 0.910
icosanoid transport GO:0071715 14 0.906
cellular divalent inorganic cation homeostasis GO:0072503 127 0.904
somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 51 0.903
positive regulation of response to wounding GO:1903036 66 0.903
acute inflammatory response GO:0002526 41 0.901
lymphocyte migration GO:0072676 26 0.898
dna recombination GO:0006310 92 0.896
regulation of lymphocyte differentiation GO:0045619 107 0.896
interleukin 12 biosynthetic process GO:0042090 8 0.886
regulation of prostaglandin secretion GO:0032306 5 0.884
regulation of defense response GO:0031347 233 0.882
positive regulation of t cell activation GO:0050870 101 0.881
somatic cell dna recombination GO:0016444 51 0.879
apoptotic signaling pathway GO:0097190 306 0.879
lymphocyte activation involved in immune response GO:0002285 93 0.871
regulation of t cell differentiation GO:0045580 83 0.871
axon ensheathment GO:0008366 76 0.871
positive regulation of lymphocyte proliferation GO:0050671 70 0.868
myeloid leukocyte activation GO:0002274 83 0.868
interleukin 5 secretion GO:0072603 2 0.864
translational initiation GO:0006413 24 0.864
protein localization to nucleus GO:0034504 121 0.864
regulation of jnk cascade GO:0046328 62 0.861
positive regulation of glial cell differentiation GO:0045687 21 0.861
salivary gland morphogenesis GO:0007435 33 0.860
t cell proliferation GO:0042098 120 0.859
defense response to gram positive bacterium GO:0050830 50 0.858
temperature homeostasis GO:0001659 26 0.857
regulation of humoral immune response GO:0002920 22 0.857
adaptive immune response GO:0002250 155 0.855
negative regulation of osteoblast differentiation GO:0045668 30 0.854
positive regulation of jnk cascade GO:0046330 46 0.851
positive regulation of hair cycle GO:0042635 7 0.849
positive regulation of cellular amine metabolic process GO:0033240 5 0.849
regulation of membrane potential GO:0042391 192 0.846
positive regulation of cytokine biosynthetic process GO:0042108 40 0.845
regulation of t cell activation GO:0050863 170 0.844
positive regulation of tumor necrosis factor superfamily cytokine production GO:1903557 31 0.842
positive regulation of heat generation GO:0031652 7 0.842
cellular response to lipopolysaccharide GO:0071222 77 0.841
antibacterial peptide biosynthetic process GO:0002780 2 0.841
regulation of leukocyte differentiation GO:1902105 159 0.840
defense response to bacterium GO:0042742 119 0.839
fatty acid derivative transport GO:1901571 14 0.838
growth involved in symbiotic interaction GO:0044110 23 0.838
positive regulation of lymphocyte activation GO:0051251 140 0.837
ensheathment of neurons GO:0007272 76 0.835
mammary gland alveolus development GO:0060749 22 0.833
regulation of inflammatory response GO:0050727 147 0.833
positive regulation of protein kinase b signaling GO:0051897 32 0.832
positive regulation of hair follicle development GO:0051798 6 0.828
regulation of antibacterial peptide production GO:0002786 1 0.827
osteoclast differentiation GO:0030316 62 0.827
negative regulation of glucose transport GO:0010829 9 0.826
cytokine biosynthetic process GO:0042089 68 0.824
jnk cascade GO:0007254 72 0.823
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.821
regulation of response to wounding GO:1903034 189 0.820
positive regulation of defense response GO:0031349 124 0.820
modulation of growth of symbiont involved in interaction with host GO:0044144 19 0.820
regulation of antibacterial peptide biosynthetic process GO:0002808 1 0.820
negative regulation of apoptotic signaling pathway GO:2001234 104 0.819
cytokine production GO:0001816 319 0.817
positive regulation of secretion by cell GO:1903532 114 0.816
hematopoietic stem cell migration GO:0035701 1 0.813
leukocyte activation involved in immune response GO:0002366 126 0.812
regulation of cytokine biosynthetic process GO:0042035 59 0.812
positive regulation of stress activated mapk cascade GO:0032874 48 0.811
cell fate commitment GO:0045165 210 0.809
extracellular matrix organization GO:0030198 147 0.809
syncytium formation GO:0006949 43 0.808
circadian rhythm GO:0007623 114 0.806
isotype switching GO:0045190 36 0.804
defense response to virus GO:0051607 68 0.802
regulation of alkaline phosphatase activity GO:0010692 6 0.802
cytokine mediated signaling pathway GO:0019221 115 0.800
regulation of protein targeting GO:1903533 61 0.799
mammary gland lobule development GO:0061377 22 0.797
positive regulation of organic acid transport GO:0032892 11 0.797
immunoglobulin production involved in immunoglobulin mediated immune response GO:0002381 43 0.791
positive regulation of lymphocyte mediated immunity GO:0002708 62 0.790
alpha beta t cell proliferation GO:0046633 21 0.790
positive regulation of regulatory t cell differentiation GO:0045591 4 0.788
cytokine metabolic process GO:0042107 71 0.786
negative regulation of endothelial cell migration GO:0010596 4 0.779
regulation of immunoglobulin secretion GO:0051023 12 0.777
necroptotic process GO:0070266 21 0.771
positive regulation of ion transport GO:0043270 65 0.767
regulation of lymphocyte migration GO:2000401 14 0.766
positive regulation of myeloid leukocyte differentiation GO:0002763 26 0.765
cellular response to cytokine stimulus GO:0071345 189 0.764
retinal cell programmed cell death GO:0046666 8 0.760
regulation of interleukin 12 biosynthetic process GO:0045075 8 0.760
branching involved in salivary gland morphogenesis GO:0060445 26 0.759
b cell mediated immunity GO:0019724 71 0.759
positive regulation of immunoglobulin mediated immune response GO:0002891 26 0.757
cell activation involved in immune response GO:0002263 126 0.755
positive regulation of lipid transport GO:0032370 22 0.752
immune complex clearance GO:0002434 2 0.749
positive regulation of neutrophil migration GO:1902624 12 0.748
negative regulation of phosphatase activity GO:0010923 5 0.747
positive regulation of jun kinase activity GO:0043507 30 0.747
extracellular structure organization GO:0043062 148 0.745
inflammatory response GO:0006954 244 0.743
regulation of interferon gamma production GO:0032649 57 0.741
negative regulation of defense response GO:0031348 77 0.741
immune response activating cell surface receptor signaling pathway GO:0002429 72 0.737
alpha beta t cell activation GO:0046631 91 0.732
cellular response to tumor necrosis factor GO:0071356 21 0.732
regulation of lymphocyte activation GO:0051249 240 0.729
alpha beta t cell differentiation GO:0046632 69 0.727
leukocyte migration GO:0050900 124 0.723
negative regulation of growth of symbiont in host GO:0044130 19 0.721
interleukin 6 production GO:0032635 58 0.718
positive regulation of osteoclast differentiation GO:0045672 15 0.716
response to tumor necrosis factor GO:0034612 26 0.716
production of molecular mediator of immune response GO:0002440 103 0.712
positive regulation of prostaglandin secretion GO:0032308 5 0.711
forebrain cell migration GO:0021885 58 0.710
regulation of homeostatic process GO:0032844 182 0.702
metal ion homeostasis GO:0055065 189 0.700
skin development GO:0043588 220 0.700
t helper 1 cell differentiation GO:0045063 13 0.700
negative regulation of ossification GO:0030279 49 0.698
eosinophil degranulation GO:0043308 1 0.697
positive regulation of syncytium formation by plasma membrane fusion GO:0060143 17 0.695
positive regulation of peptide hormone secretion GO:0090277 31 0.694
positive regulation of t cell differentiation GO:0045582 52 0.692
positive regulation of translation GO:0045727 19 0.692
amine metabolic process GO:0009308 45 0.685
positive regulation of muscle cell differentiation GO:0051149 39 0.685
regulation of oligodendrocyte differentiation GO:0048713 23 0.684
acute phase response GO:0006953 10 0.682
positive regulation of corticotropin releasing hormone secretion GO:0051466 1 0.679
positive regulation of antimicrobial peptide biosynthetic process GO:0002807 1 0.679
programmed necrotic cell death GO:0097300 28 0.678
positive regulation of defense response to bacterium GO:1900426 1 0.677
interleukin 13 secretion GO:0072611 2 0.677
cd4 positive alpha beta t cell differentiation GO:0043367 41 0.676
telencephalon development GO:0021537 186 0.676
regulation of lymphocyte mediated immunity GO:0002706 84 0.675
regulation of extrinsic apoptotic signaling pathway GO:2001236 77 0.675
negative regulation of interleukin 5 secretion GO:2000663 1 0.671
cd4 positive alpha beta t cell activation GO:0035710 45 0.671
regulation of myotube differentiation GO:0010830 62 0.670
positive regulation of hydrolase activity GO:0051345 148 0.666
gland development GO:0048732 330 0.663
oligodendrocyte differentiation GO:0048709 53 0.663
response to lipopolysaccharide GO:0032496 128 0.653
regulation of cd4 positive alpha beta t cell activation GO:2000514 24 0.650
neuronal action potential GO:0019228 54 0.649
positive regulation of t cell migration GO:2000406 10 0.648
cell fate determination GO:0001709 32 0.647
negative regulation of multi organism process GO:0043901 68 0.647
protein targeting GO:0006605 143 0.645
regulation of immunoglobulin production GO:0002637 42 0.644
regulation of tolerance induction dependent upon immune response GO:0002652 1 0.644
positive regulation of lymphocyte migration GO:2000403 11 0.642
gliogenesis GO:0042063 141 0.640
membrane invagination GO:0010324 17 0.640
hair cycle GO:0042633 90 0.638
positive regulation of cell development GO:0010720 237 0.635
pigment metabolic process GO:0042440 32 0.632
positive regulation of antimicrobial peptide production GO:0002225 1 0.631
regulation of chronic inflammatory response GO:0002676 7 0.629
thymic t cell selection GO:0045061 22 0.627
regulation of interleukin 2 production GO:0032663 28 0.626
positive regulation of cysteine type endopeptidase activity GO:2001056 39 0.624
defense response to gram negative bacterium GO:0050829 28 0.623
nik nf kappab signaling GO:0038061 14 0.619
regulation of branching involved in salivary gland morphogenesis GO:0060693 11 0.619
regulation of organ morphogenesis GO:2000027 144 0.615
myeloid cell activation involved in immune response GO:0002275 34 0.615
melanin metabolic process GO:0006582 12 0.613
regulation of alpha beta t cell differentiation GO:0046637 35 0.610
regulation of t cell migration GO:2000404 12 0.609
regulation of stress activated mapk cascade GO:0032872 69 0.608
immune response regulating signaling pathway GO:0002764 125 0.607
regulation of antimicrobial humoral response GO:0002759 3 0.606
regulation of hair follicle development GO:0051797 9 0.604
regulation of tumor necrosis factor production GO:0032680 49 0.602
intrinsic apoptotic signaling pathway GO:0097193 132 0.597
positive regulation of interleukin 6 production GO:0032755 37 0.594
lymphocyte mediated immunity GO:0002449 139 0.591
isotype switching to igg isotypes GO:0048291 10 0.591
regulation of multi organism process GO:0043900 111 0.588
positive regulation of peptide secretion GO:0002793 33 0.587
regulation of cd4 positive alpha beta t cell differentiation GO:0043370 21 0.585
guanosine containing compound metabolic process GO:1901068 144 0.582
regulation of lymphocyte proliferation GO:0050670 117 0.573
cellular response to biotic stimulus GO:0071216 92 0.571
mammary gland epithelial cell proliferation GO:0033598 24 0.571
cellular amine metabolic process GO:0044106 44 0.570
protein homooligomerization GO:0051260 43 0.568
dephosphorylation GO:0016311 129 0.565
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 87 0.564
regulation of gliogenesis GO:0014013 50 0.563
cellular response to dna damage stimulus GO:0006974 207 0.563
single organism nuclear import GO:1902593 95 0.561
antimicrobial peptide biosynthetic process GO:0002777 2 0.558
regulation of isotype switching to igg isotypes GO:0048302 10 0.556
positive regulation of transcription factor import into nucleus GO:0042993 8 0.555
cd8 positive alpha beta t cell extravasation GO:0035697 3 0.555
spleen development GO:0048536 39 0.554
calcium ion transport GO:0006816 159 0.549
positive regulation of gtpase activity GO:0043547 85 0.547
regulation of cytokine secretion involved in immune response GO:0002739 4 0.547
regulation of interleukin 10 secretion GO:2001179 4 0.541
activation of innate immune response GO:0002218 56 0.540
carboxylic acid transport GO:0046942 100 0.531
protein import into nucleus GO:0006606 95 0.529
negative regulation of exocytosis GO:0045920 12 0.522
regulation of protein secretion GO:0050708 82 0.521
positive regulation of peptidase activity GO:0010952 49 0.520
establishment of protein localization to organelle GO:0072594 118 0.518
regulation of antimicrobial peptide production GO:0002784 1 0.517
t cell extravasation GO:0072683 4 0.514
negative regulation of odontogenesis of dentin containing tooth GO:0042489 1 0.514
hepaticobiliary system development GO:0061008 67 0.513
stress activated mapk cascade GO:0051403 80 0.513
regulation of map kinase activity GO:0043405 120 0.512
regulation of b cell mediated immunity GO:0002712 37 0.512
cell chemotaxis GO:0060326 81 0.511
mucosal associated lymphoid tissue development GO:0048537 12 0.511
follicular dendritic cell differentiation GO:0002268 2 0.508
leukocyte mediated immunity GO:0002443 174 0.504
regulation of tumor necrosis factor superfamily cytokine production GO:1903555 50 0.504
epidermis development GO:0008544 187 0.501
activation of cysteine type endopeptidase activity GO:0097202 27 0.499
organic anion transport GO:0015711 137 0.497
positive regulation of humoral immune response GO:0002922 11 0.497
positive regulation of innate immune response GO:0045089 80 0.494
organic hydroxy compound metabolic process GO:1901615 203 0.494
regulation of striated muscle cell differentiation GO:0051153 81 0.491
regulation of apoptotic signaling pathway GO:2001233 197 0.487
innate immune response activating signal transduction GO:0002758 50 0.487
calcium ion homeostasis GO:0055074 127 0.484
regulation of cellular response to stress GO:0080135 159 0.484
cytokine production involved in immune response GO:0002367 34 0.483
t cell selection GO:0045058 34 0.480
regulation of interleukin 12 production GO:0032655 30 0.480
stress activated protein kinase signaling cascade GO:0031098 81 0.479
negative regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001240 16 0.474
regulation of tumor necrosis factor biosynthetic process GO:0042534 10 0.473
acid secretion GO:0046717 33 0.471
regulation of glial cell differentiation GO:0045685 41 0.470
positive regulation of monocyte chemotaxis GO:0090026 2 0.468
icosanoid secretion GO:0032309 12 0.466
positive regulation of monocyte extravasation GO:2000439 1 0.465
positive regulation of chemotaxis GO:0050921 38 0.462
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 62 0.461
negative regulation of signal transduction in absence of ligand GO:1901099 16 0.461
positive regulation of oligodendrocyte differentiation GO:0048714 9 0.455
regulation of phosphatase activity GO:0010921 12 0.452
regulation of protein localization to nucleus GO:1900180 60 0.451
regulation of t cell chemotaxis GO:0010819 5 0.449
transmission of nerve impulse GO:0019226 76 0.448
molting cycle GO:0042303 90 0.447
regulation of intracellular transport GO:0032386 159 0.446
striated muscle cell development GO:0055002 125 0.442
osteoclast development GO:0036035 9 0.442
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.442
lymphocyte costimulation GO:0031294 15 0.440
positive regulation of immune effector process GO:0002699 107 0.433
positive regulation of immunological synapse formation GO:2000522 1 0.433
regulation of epidermis development GO:0045682 33 0.431
necrotic cell death GO:0070265 30 0.431
regulation of leukocyte mediated immunity GO:0002703 104 0.430
regulation of fatty acid transport GO:2000191 10 0.429
regulation of cellular amine metabolic process GO:0033238 20 0.429
regulation of defense response to bacterium GO:1900424 3 0.428
response to muramyl dipeptide GO:0032495 9 0.424
t helper 2 cell differentiation GO:0045064 12 0.424
innate immune response GO:0045087 157 0.424
germinal center formation GO:0002467 16 0.420
cellular response to organonitrogen compound GO:0071417 145 0.416
leukocyte chemotaxis GO:0030595 69 0.415
translation GO:0006412 93 0.414
negative regulation of muscle cell differentiation GO:0051148 33 0.413
neuroblast differentiation GO:0014016 2 0.405
phenol containing compound metabolic process GO:0018958 60 0.403
apical protein localization GO:0045176 7 0.402
regulation of anion transport GO:0044070 27 0.401
regulation of protein complex assembly GO:0043254 83 0.401
regulation of dendritic cell chemotaxis GO:2000508 1 0.398
apoptotic cell clearance GO:0043277 17 0.398
positive regulation of proteolysis GO:0045862 85 0.397
regulation of regulated secretory pathway GO:1903305 20 0.396
regulation of intracellular protein transport GO:0033157 82 0.396
regulation of humoral immune response mediated by circulating immunoglobulin GO:0002923 10 0.395
nuclear import GO:0051170 95 0.393
regulation of cytokine secretion GO:0050707 61 0.391
glial cell apoptotic process GO:0034349 3 0.390
positive regulation of protein import into nucleus GO:0042307 26 0.389
negative regulation of cytokine secretion GO:0050710 15 0.388
negative regulation of dephosphorylation GO:0035305 9 0.387
negative regulation of chronic inflammatory response GO:0002677 3 0.385
positive regulation of b cell activation GO:0050871 49 0.380
bone resorption GO:0045453 38 0.379
dna metabolic process GO:0006259 303 0.377
eosinophil activation involved in immune response GO:0002278 1 0.377
oligodendrocyte development GO:0014003 20 0.377
eosinophil activation GO:0043307 1 0.375
gtp metabolic process GO:0046039 144 0.374
regulation of transcription factor import into nucleus GO:0042990 24 0.367
positive regulation of hormone secretion GO:0046887 38 0.367
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.366
muscle tissue development GO:0060537 308 0.366
pattern recognition receptor signaling pathway GO:0002221 47 0.364
epithelial cell proliferation GO:0050673 174 0.363
cellular amino acid metabolic process GO:0006520 103 0.363
tumor necrosis factor superfamily cytokine production GO:0071706 51 0.363
regulation of osteoclast differentiation GO:0045670 36 0.362
chemotaxis GO:0006935 247 0.361
carbohydrate metabolic process GO:0005975 230 0.358
neutrophil differentiation GO:0030223 3 0.358
regulation of lymphocyte chemotaxis GO:1901623 6 0.356
cellular chemical homeostasis GO:0055082 215 0.355
positive regulation of cell migration GO:0030335 109 0.352
alpha beta t cell activation involved in immune response GO:0002287 31 0.351
lymphocyte chemotaxis GO:0048247 10 0.350
exocrine system development GO:0035272 45 0.348
positive regulation of gliogenesis GO:0014015 27 0.347
positive regulation of behavior GO:0048520 40 0.347
positive regulation of cytoplasmic transport GO:1903651 40 0.345
cation homeostasis GO:0055080 212 0.345
regulation of myeloid cell differentiation GO:0045637 96 0.344
regulation of mast cell activation GO:0033003 21 0.343
defense response to protozoan GO:0042832 25 0.342
purine nucleoside catabolic process GO:0006152 205 0.340
regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001239 26 0.340
zymogen activation GO:0031638 41 0.340
regulation of interleukin 13 secretion GO:2000665 2 0.339
regulation of reactive oxygen species metabolic process GO:2000377 40 0.338
tumor necrosis factor biosynthetic process GO:0042533 10 0.337
organic acid transport GO:0015849 101 0.336
positive regulation of cytosolic calcium ion concentration GO:0007204 65 0.334
somatic diversification of immune receptors GO:0002200 53 0.333
sensory organ morphogenesis GO:0090596 242 0.330
positive regulation of map kinase activity GO:0043406 84 0.327
negative regulation of inflammatory response GO:0050728 61 0.325
positive regulation of dendritic cell chemotaxis GO:2000510 1 0.325
protein kinase b signaling GO:0043491 74 0.323
antigen receptor mediated signaling pathway GO:0050851 64 0.322
regulation of protein localization GO:0032880 231 0.321
positive regulation of inflammatory response GO:0050729 47 0.321
mapk cascade GO:0000165 281 0.319
regulation of organic acid transport GO:0032890 16 0.318
t helper 1 type immune response GO:0042088 25 0.316
multicellular organismal signaling GO:0035637 91 0.315
myeloid dendritic cell differentiation GO:0043011 16 0.315
positive regulation of fatty acid transport GO:2000193 8 0.313
growth of symbiont involved in interaction with host GO:0044116 23 0.313
negative regulation of cell proliferation GO:0008285 296 0.312
response to organonitrogen compound GO:0010243 246 0.312
regulation of secretion GO:0051046 274 0.309
regulation of innate immune response GO:0045088 91 0.309
regulation of monocyte extravasation GO:2000437 2 0.308
response to molecule of bacterial origin GO:0002237 143 0.308
striated muscle tissue development GO:0014706 293 0.307
muscle cell development GO:0055001 133 0.307
integrin activation GO:0033622 8 0.307
t cell differentiation involved in immune response GO:0002292 30 0.307
regulation of jun kinase activity GO:0043506 40 0.305
cytokine secretion involved in immune response GO:0002374 6 0.304
multicellular organismal homeostasis GO:0048871 164 0.303
positive regulation of programmed cell death GO:0043068 218 0.303
regulation of ion transport GO:0043269 215 0.303
positive regulation of cell death GO:0010942 224 0.301
pallium development GO:0021543 120 0.300
cellular extravasation GO:0045123 17 0.300
prostaglandin secretion GO:0032310 5 0.299
regulation of translation GO:0006417 71 0.292
extrinsic apoptotic signaling pathway via death domain receptors GO:0008625 34 0.292
humoral immune response mediated by circulating immunoglobulin GO:0002455 14 0.290
action potential GO:0001508 78 0.287
glial cell differentiation GO:0010001 131 0.287
regulation of epithelial cell proliferation GO:0050678 141 0.286
regulation of ossification GO:0030278 112 0.286
regulation of cell motility GO:2000145 236 0.285
immune response regulating cell surface receptor signaling pathway GO:0002768 80 0.281
positive regulation of antibacterial peptide production GO:0002803 1 0.280
eosinophil mediated immunity GO:0002447 1 0.277
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 36 0.275
regulation of t cell extravasation GO:2000407 3 0.275
telencephalon cell migration GO:0022029 55 0.274
bone remodeling GO:0046849 53 0.274
positive regulation of b cell mediated immunity GO:0002714 26 0.271
regulation of hydrolase activity GO:0051336 246 0.269
interferon beta biosynthetic process GO:0045350 4 0.268
neuromuscular synaptic transmission GO:0007274 16 0.267

Map3k14 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
primary immunodeficiency disease DOID:612 0 0.291
blood protein disease DOID:620 0 0.291
immune system disease DOID:2914 0 0.291
agammaglobulinemia DOID:2583 0 0.291
disease of anatomical entity DOID:7 0 0.291
common variable immunodeficiency DOID:12177 0 0.291
b cell deficiency DOID:2115 0 0.291
hematopoietic system disease DOID:74 0 0.291