Mus musculus

27 known processes

Shisa5

shisa homolog 5 (Xenopus laevis)

(Aliases: 2310008D10Rik,Scotin,mShisa5,6430628I05Rik)

Shisa5 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
actin cytoskeleton organization GO:0030036 220 0.516
regulation of actin filament polymerization GO:0030833 38 0.493
regulation of actin polymerization or depolymerization GO:0008064 45 0.416
regulation of actin filament length GO:0030832 45 0.404
regulation of intracellular transport GO:0032386 159 0.365
positive regulation of t cell mediated cytotoxicity GO:0001916 15 0.311
actin filament polymerization GO:0030041 44 0.284
actin polymerization or depolymerization GO:0008154 54 0.246
immune effector process GO:0002252 321 0.244
defense response to other organism GO:0098542 197 0.233
regulation of actin nucleation GO:0051125 4 0.208
regulation of cellular amine metabolic process GO:0033238 20 0.204
t cell mediated immunity GO:0002456 50 0.203
macromolecule catabolic process GO:0009057 281 0.199
t cell activation GO:0042110 289 0.197
metal ion homeostasis GO:0055065 189 0.186
adaptive immune response GO:0002250 155 0.174
positive regulation of rho gtpase activity GO:0032321 41 0.168
epithelial cell proliferation GO:0050673 174 0.168
ribonucleoside triphosphate metabolic process GO:0009199 220 0.164
protein polymerization GO:0051258 57 0.161
rho protein signal transduction GO:0007266 32 0.154
cation homeostasis GO:0055080 212 0.153
regulation of actin filament based process GO:0032970 99 0.143
actin filament organization GO:0007015 113 0.142
nucleoside triphosphate catabolic process GO:0009143 205 0.133
hormone metabolic process GO:0042445 86 0.133
cellular response to cytokine stimulus GO:0071345 189 0.133
regulation of actin cytoskeleton organization GO:0032956 84 0.132
cellular protein complex assembly GO:0043623 116 0.128
regulation of protein localization GO:0032880 231 0.128
cellular amine metabolic process GO:0044106 44 0.128
leukocyte migration GO:0050900 124 0.127
positive regulation of actin filament polymerization GO:0030838 26 0.126
negative regulation of molecular function GO:0044092 258 0.126
regulation of cell motility GO:2000145 236 0.124
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.124
apoptotic signaling pathway GO:0097190 306 0.119
divalent inorganic cation transport GO:0072511 178 0.115
regulation of lamellipodium assembly GO:0010591 3 0.114
gland development GO:0048732 330 0.113
regulation of cellular component size GO:0032535 121 0.107
muscle tissue development GO:0060537 308 0.105
negative regulation of phosphorus metabolic process GO:0010563 184 0.104
organonitrogen compound catabolic process GO:1901565 264 0.099
positive regulation of innate immune response GO:0045089 80 0.099
t cell activation involved in immune response GO:0002286 43 0.095
embryonic olfactory bulb interneuron precursor migration GO:0021831 2 0.093
purine ribonucleoside metabolic process GO:0046128 241 0.093
regulation of cytokine production GO:0001817 266 0.091
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.089
glycosyl compound metabolic process GO:1901657 246 0.088
calcium ion transport GO:0006816 159 0.088
protein catabolic process GO:0030163 221 0.088
positive regulation of cellular component biogenesis GO:0044089 94 0.087
negative regulation of homeostatic process GO:0032845 71 0.087
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.087
cellular metal ion homeostasis GO:0006875 151 0.086
interspecies interaction between organisms GO:0044419 83 0.085
regulation of cellular component biogenesis GO:0044087 181 0.082
sequestering of calcium ion GO:0051208 18 0.081
innate immune response GO:0045087 157 0.080
striated muscle tissue development GO:0014706 293 0.078
muscle cell development GO:0055001 133 0.077
maintenance of location GO:0051235 89 0.076
leukocyte mediated immunity GO:0002443 174 0.074
peptidyl tyrosine phosphorylation GO:0018108 143 0.073
germ cell development GO:0007281 185 0.073
positive regulation of actin nucleation GO:0051127 3 0.072
arp2 3 complex mediated actin nucleation GO:0034314 3 0.072
sphingosine metabolic process GO:0006670 4 0.070
calcium ion homeostasis GO:0055074 127 0.068
regulation of cellular amino acid metabolic process GO:0006521 5 0.068
modification dependent macromolecule catabolic process GO:0043632 133 0.067
cellular divalent inorganic cation homeostasis GO:0072503 127 0.067
ossification GO:0001503 216 0.066
rac protein signal transduction GO:0016601 13 0.066
response to organic cyclic compound GO:0014070 198 0.066
nucleotide metabolic process GO:0009117 332 0.064
cation transport GO:0006812 399 0.064
ribonucleotide metabolic process GO:0009259 291 0.062
organonitrogen compound biosynthetic process GO:1901566 192 0.062
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.062
regulation of intracellular protein transport GO:0033157 82 0.061
t cell mediated cytotoxicity GO:0001913 26 0.061
divalent metal ion transport GO:0070838 172 0.060
positive regulation of cytoskeleton organization GO:0051495 49 0.060
cell adhesion GO:0007155 329 0.060
reactive oxygen species biosynthetic process GO:1903409 8 0.059
immune response regulating signaling pathway GO:0002764 125 0.059
hair follicle morphogenesis GO:0031069 29 0.058
nucleoside catabolic process GO:0009164 206 0.058
cerebral cortex tangential migration using cell axon interactions GO:0021824 3 0.056
regulation of cytoplasmic transport GO:1903649 112 0.055
purine nucleotide biosynthetic process GO:0006164 65 0.055
cellular response to growth factor stimulus GO:0071363 197 0.054
nucleobase containing small molecule metabolic process GO:0055086 352 0.054
lymphocyte mediated immunity GO:0002449 139 0.054
myosin filament organization GO:0031033 3 0.054
regulation of nucleotide metabolic process GO:0006140 169 0.054
regulation of hormone levels GO:0010817 211 0.054
regulation of mast cell differentiation GO:0060375 3 0.053
positive regulation of programmed cell death GO:0043068 218 0.053
antigen processing and presentation of endogenous peptide antigen via mhc class i via er pathway GO:0002484 3 0.053
carbohydrate derivative catabolic process GO:1901136 231 0.053
developmental maturation GO:0021700 193 0.053
iron ion import into cell GO:0097459 4 0.052
cell type specific apoptotic process GO:0097285 268 0.052
cellular amino acid metabolic process GO:0006520 103 0.052
purine ribonucleotide catabolic process GO:0009154 208 0.052
positive regulation of cellular amine metabolic process GO:0033240 5 0.051
intracellular protein transport GO:0006886 204 0.051
peptidyl tyrosine modification GO:0018212 145 0.051
nucleoside metabolic process GO:0009116 246 0.051
regulation of reactive oxygen species metabolic process GO:2000377 40 0.051
leukocyte differentiation GO:0002521 342 0.050
sequestering of metal ion GO:0051238 19 0.050
negative regulation of cell proliferation GO:0008285 296 0.050
negative regulation of cellular component organization GO:0051129 194 0.049
regulation of cytoskeleton organization GO:0051493 122 0.049
regulation of purine nucleotide metabolic process GO:1900542 169 0.049
regulation of arp2 3 complex mediated actin nucleation GO:0034315 1 0.048
skin development GO:0043588 220 0.047
regulation of rho gtpase activity GO:0032319 58 0.047
protein ubiquitination GO:0016567 171 0.047
regulation of cell migration GO:0030334 219 0.047
regulation of apoptotic signaling pathway GO:2001233 197 0.046
ras protein signal transduction GO:0007265 77 0.046
cellular macromolecule catabolic process GO:0044265 206 0.046
cytokine mediated signaling pathway GO:0019221 115 0.046
regulation of calcium ion transport GO:0051924 69 0.046
carbohydrate metabolic process GO:0005975 230 0.045
small gtpase mediated signal transduction GO:0007264 97 0.045
positive regulation of defense response GO:0031349 124 0.044
positive regulation of production of molecular mediator of immune response GO:0002702 45 0.044
positive regulation of cell death GO:0010942 224 0.044
peptidyl amino acid modification GO:0018193 336 0.044
morphogenesis of a branching epithelium GO:0061138 193 0.043
regulation of cell killing GO:0031341 40 0.043
glycolipid metabolic process GO:0006664 25 0.043
regulation of anatomical structure size GO:0090066 178 0.042
syncytium formation GO:0006949 43 0.042
actin filament bundle assembly GO:0051017 40 0.042
central nervous system neuron differentiation GO:0021953 162 0.042
myeloid cell homeostasis GO:0002262 114 0.041
regulation of metal ion transport GO:0010959 106 0.041
leukocyte cell cell adhesion GO:0007159 14 0.040
positive regulation of cytosolic calcium ion concentration GO:0007204 65 0.040
purine nucleoside metabolic process GO:0042278 241 0.040
regulation of calcium ion transport into cytosol GO:0010522 31 0.040
regulation of membrane potential GO:0042391 192 0.040
regulation of cell projection organization GO:0031344 206 0.039
regulation of defense response GO:0031347 233 0.039
positive regulation of leukocyte apoptotic process GO:2000108 21 0.038
regulation of proteolysis GO:0030162 164 0.038
innate immune response activating signal transduction GO:0002758 50 0.038
ear development GO:0043583 200 0.038
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.038
regulation of ras gtpase activity GO:0032318 88 0.038
cytokine production GO:0001816 319 0.037
peptide transport GO:0015833 133 0.037
hair cycle GO:0042633 90 0.037
heterocycle catabolic process GO:0046700 280 0.036
epithelial cell development GO:0002064 159 0.036
lymphocyte differentiation GO:0030098 242 0.036
cellular ion homeostasis GO:0006873 165 0.035
ubiquitin dependent protein catabolic process GO:0006511 129 0.035
hair cell differentiation GO:0035315 40 0.035
production of molecular mediator of immune response GO:0002440 103 0.035
lipid storage GO:0019915 36 0.035
glycosphingolipid catabolic process GO:0046479 5 0.035
response to organonitrogen compound GO:0010243 246 0.035
ribose phosphate metabolic process GO:0019693 291 0.034
nucleoside phosphate metabolic process GO:0006753 338 0.034
negative regulation of intracellular signal transduction GO:1902532 167 0.034
ribonucleotide catabolic process GO:0009261 208 0.034
regulation of protein complex assembly GO:0043254 83 0.034
protein modification by small protein conjugation or removal GO:0070647 207 0.034
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.033
purine ribonucleotide metabolic process GO:0009150 290 0.033
cardiac muscle tissue development GO:0048738 130 0.033
regulation of cell shape GO:0008360 39 0.033
ion transmembrane transport GO:0034220 361 0.033
regulation of myd88 dependent toll like receptor signaling pathway GO:0034124 2 0.033
gtp catabolic process GO:0006184 143 0.033
uropod organization GO:0032796 2 0.033
reactive nitrogen species metabolic process GO:2001057 0 0.033
regulation of ion transport GO:0043269 215 0.033
reactive oxygen species metabolic process GO:0072593 84 0.032
negative regulation of protein modification process GO:0031400 163 0.032
negative regulation of cytokine production GO:0001818 84 0.032
molting cycle GO:0042303 90 0.032
negative regulation of protein metabolic process GO:0051248 282 0.032
positive regulation of nucleoside metabolic process GO:0045979 91 0.032
endocytosis GO:0006897 168 0.032
ribonucleoside metabolic process GO:0009119 245 0.032
ceramide biosynthetic process GO:0046513 20 0.032
regulation of lymphocyte mediated immunity GO:0002706 84 0.032
regulation of protein localization to nucleus GO:1900180 60 0.032
striated muscle cell development GO:0055002 125 0.031
mapk cascade GO:0000165 281 0.031
negative regulation of phosphate metabolic process GO:0045936 184 0.031
calcium ion transport into cytosol GO:0060402 48 0.031
regulation of myd88 independent toll like receptor signaling pathway GO:0034127 1 0.031
sphingoid metabolic process GO:0046519 5 0.031
viral process GO:0016032 41 0.031
cell substrate adhesion GO:0031589 130 0.031
negative regulation of apoptotic signaling pathway GO:2001234 104 0.031
cell activation involved in immune response GO:0002263 126 0.031
cd4 positive alpha beta t cell activation GO:0035710 45 0.031
cellular nitrogen compound catabolic process GO:0044270 280 0.031
regulation of t cell activation GO:0050863 170 0.031
cellular homeostasis GO:0019725 240 0.030
interleukin 17 production GO:0032620 11 0.030
branching morphogenesis of an epithelial tube GO:0048754 159 0.030
lymphocyte activation involved in immune response GO:0002285 93 0.030
inflammatory response GO:0006954 244 0.030
positive regulation of organelle organization GO:0010638 128 0.030
symbiosis encompassing mutualism through parasitism GO:0044403 83 0.030
extrinsic apoptotic signaling pathway GO:0097191 126 0.030
purine containing compound catabolic process GO:0072523 213 0.030
cell killing GO:0001906 67 0.030
negative regulation of vesicle fusion GO:0031339 1 0.030
regulation of ras protein signal transduction GO:0046578 114 0.030
purine nucleotide catabolic process GO:0006195 211 0.029
nucleocytoplasmic transport GO:0006913 139 0.029
regulation of binding GO:0051098 111 0.029
purine nucleoside triphosphate catabolic process GO:0009146 203 0.028
alpha beta t cell activation GO:0046631 91 0.028
epidermis morphogenesis GO:0048730 33 0.028
purine nucleoside triphosphate metabolic process GO:0009144 226 0.028
t cell differentiation GO:0030217 174 0.028
neuromuscular process GO:0050905 99 0.028
phagocytosis GO:0006909 66 0.028
establishment or maintenance of cell polarity GO:0007163 86 0.027
protein targeting GO:0006605 143 0.027
regulation of homeostatic process GO:0032844 182 0.027
male sex differentiation GO:0046661 109 0.027
negative regulation of cell migration GO:0030336 59 0.027
sensory organ morphogenesis GO:0090596 242 0.027
nucleoside phosphate biosynthetic process GO:1901293 79 0.027
eye photoreceptor cell differentiation GO:0001754 41 0.027
regulation of protein catabolic process GO:0042176 108 0.027
regulation of peptidase activity GO:0052547 96 0.027
positive regulation of apoptotic signaling pathway GO:2001235 95 0.027
negative regulation of protein phosphorylation GO:0001933 126 0.027
regulation of osteoblast differentiation GO:0045667 67 0.027
regulation of organelle organization GO:0033043 289 0.026
negative regulation of growth GO:0045926 99 0.026
entry into other organism involved in symbiotic interaction GO:0051828 15 0.026
negative regulation of phosphorylation GO:0042326 166 0.026
positive regulation of lamellipodium organization GO:1902745 3 0.026
positive regulation of cell development GO:0010720 237 0.026
glycolipid catabolic process GO:0019377 5 0.026
cellular protein catabolic process GO:0044257 155 0.026
nucleoside phosphate catabolic process GO:1901292 222 0.026
female sex differentiation GO:0046660 84 0.025
endothelial cell migration GO:0043542 44 0.025
protein maturation GO:0051604 176 0.025
regulation of viral transcription GO:0046782 3 0.025
carbohydrate derivative biosynthetic process GO:1901137 183 0.025
cellular ketone metabolic process GO:0042180 84 0.025
antigen processing and presentation of exogenous peptide antigen GO:0002478 21 0.025
regulation of t cell mediated immunity GO:0002709 34 0.025
glycosylceramide metabolic process GO:0006677 4 0.025
myosin filament assembly GO:0031034 2 0.024
meiotic cell cycle GO:0051321 122 0.024
protein localization to organelle GO:0033365 185 0.024
epinephrine secretion GO:0048242 1 0.024
regulation of multi organism process GO:0043900 111 0.024
response to growth factor GO:0070848 198 0.024
organelle fission GO:0048285 170 0.024
nucleotide catabolic process GO:0009166 217 0.024
positive regulation of hydrolase activity GO:0051345 148 0.024
hormone biosynthetic process GO:0042446 16 0.024
tissue homeostasis GO:0001894 115 0.024
synaptic transmission GO:0007268 329 0.024
negative regulation of viral process GO:0048525 23 0.024
entry into cell of other organism involved in symbiotic interaction GO:0051806 15 0.024
cytosolic calcium ion homeostasis GO:0051480 70 0.023
nitric oxide metabolic process GO:0046209 25 0.023
syncytium formation by plasma membrane fusion GO:0000768 42 0.023
nuclear division GO:0000280 158 0.023
negative regulation of protein transport GO:0051224 46 0.023
gonad development GO:0008406 141 0.023
modification dependent protein catabolic process GO:0019941 133 0.023
positive regulation of cytokine production GO:0001819 174 0.023
purine containing compound metabolic process GO:0072521 311 0.023
developmental growth involved in morphogenesis GO:0060560 138 0.023
regulation of nucleoside metabolic process GO:0009118 130 0.023
positive regulation of immune effector process GO:0002699 107 0.023
nitrogen compound transport GO:0071705 271 0.023
positive regulation of ras gtpase activity GO:0032320 65 0.022
negative regulation of lymphocyte activation GO:0051250 91 0.022
hair follicle cell proliferation GO:0071335 3 0.022
neuromuscular process controlling balance GO:0050885 59 0.022
negative regulation of viral transcription GO:0032897 3 0.022
regulation of establishment of protein localization GO:0070201 181 0.022
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 62 0.022
protein modification by small protein conjugation GO:0032446 187 0.022
positive regulation of vesicle fusion GO:0031340 2 0.022
carbohydrate homeostasis GO:0033500 128 0.022
alcohol metabolic process GO:0006066 116 0.022
pattern recognition receptor signaling pathway GO:0002221 47 0.022
regulation of hydrolase activity GO:0051336 246 0.021
regulation of mast cell apoptotic process GO:0033025 5 0.021
positive regulation of cell motility GO:2000147 116 0.021
epithelial tube morphogenesis GO:0060562 303 0.021
forebrain neuron differentiation GO:0021879 52 0.021
response to molecule of bacterial origin GO:0002237 143 0.021
meiotic cell cycle process GO:1903046 77 0.021
ruffle organization GO:0031529 16 0.021
locomotory behavior GO:0007626 195 0.021
progesterone metabolic process GO:0042448 4 0.021
heart process GO:0003015 94 0.021
multicellular organism growth GO:0035264 161 0.021
urinary tract smooth muscle contraction GO:0014848 6 0.021
cellular chemical homeostasis GO:0055082 215 0.020
regionalization GO:0003002 337 0.020
retinal cone cell development GO:0046549 8 0.020
regulation of cellular catabolic process GO:0031329 242 0.020
muscle cell differentiation GO:0042692 261 0.020
epidermis development GO:0008544 187 0.020
guanosine containing compound catabolic process GO:1901069 144 0.020
cellular calcium ion homeostasis GO:0006874 119 0.020
regulation of neuron apoptotic process GO:0043523 122 0.020
regulation of mapk cascade GO:0043408 248 0.020
ribose phosphate biosynthetic process GO:0046390 59 0.020
hair follicle development GO:0001942 85 0.020
regulation of extrinsic apoptotic signaling pathway GO:2001236 77 0.020
regulation of organ morphogenesis GO:2000027 144 0.020
protein import GO:0017038 101 0.019
regulation of nucleotide catabolic process GO:0030811 122 0.019
regulation of cellular ketone metabolic process GO:0010565 66 0.019
response to light stimulus GO:0009416 135 0.019
stem cell differentiation GO:0048863 268 0.019
ceramide metabolic process GO:0006672 31 0.019
regulation of lymphocyte activation GO:0051249 240 0.019
positive regulation of cell projection organization GO:0031346 95 0.019
regulation of system process GO:0044057 200 0.019
regulation of production of molecular mediator of immune response GO:0002700 65 0.019
leukocyte mediated cytotoxicity GO:0001909 62 0.019
notch signaling pathway GO:0007219 71 0.019
cytosolic calcium ion transport GO:0060401 48 0.019
response to interleukin 4 GO:0070670 23 0.019
regulation of protein heterodimerization activity GO:0043497 2 0.019
sphingolipid metabolic process GO:0006665 45 0.018
immune response activating signal transduction GO:0002757 116 0.018
endothelial cell differentiation GO:0045446 41 0.018
viral gene expression GO:0019080 3 0.018
regulation of peptide transport GO:0090087 91 0.018
regulation of cell activation GO:0050865 289 0.018
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.018
cytokine production involved in immune response GO:0002367 34 0.018
modulation by virus of host morphology or physiology GO:0019048 3 0.018
negative regulation of viral entry into host cell GO:0046597 10 0.018
cytoplasmic transport GO:0016482 234 0.018
rhythmic process GO:0048511 174 0.018
protein localization to plasma membrane GO:0072659 57 0.018
response to dsrna GO:0043331 30 0.018
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.018
inner ear receptor cell differentiation GO:0060113 61 0.018
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.018
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.018
blastocyst development GO:0001824 80 0.017
amide transport GO:0042886 138 0.017
activation of immune response GO:0002253 138 0.017
regulation of epithelial cell proliferation GO:0050678 141 0.017
establishment or maintenance of bipolar cell polarity GO:0061245 21 0.017
regulation of heart contraction GO:0008016 77 0.017
nucleotide biosynthetic process GO:0009165 78 0.017
negative regulation of cellular protein metabolic process GO:0032269 247 0.017
protein export from nucleus GO:0006611 20 0.017
blood circulation GO:0008015 195 0.017
regulation of protein transport GO:0051223 163 0.017
aromatic compound catabolic process GO:0019439 286 0.017
cell growth GO:0016049 130 0.017
negative regulation of organelle organization GO:0010639 90 0.017
macrophage fusion GO:0034238 3 0.017
posttranscriptional regulation of gene expression GO:0010608 155 0.017
negative regulation of multi organism process GO:0043901 68 0.017
semaphorin plexin signaling pathway GO:0071526 21 0.017
regulation of cyclase activity GO:0031279 13 0.017
sphingolipid biosynthetic process GO:0030148 26 0.017
purine ribonucleoside catabolic process GO:0046130 205 0.017
establishment of organelle localization GO:0051656 122 0.017
response to monosaccharide GO:0034284 67 0.016
divalent inorganic cation homeostasis GO:0072507 138 0.016
maintenance of protein location in cell GO:0032507 20 0.016
leukocyte homeostasis GO:0001776 79 0.016
positive regulation of protein complex assembly GO:0031334 45 0.016
response to acid chemical GO:0001101 111 0.016
morphogenesis of a branching structure GO:0001763 203 0.016
olfactory bulb interneuron differentiation GO:0021889 12 0.016
glucose homeostasis GO:0042593 128 0.016
negative regulation of neuron death GO:1901215 98 0.016
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 52 0.016
lamellipodium organization GO:0097581 29 0.016
dephosphorylation GO:0016311 129 0.016
nuclear transport GO:0051169 139 0.016
membrane lipid metabolic process GO:0006643 53 0.016
cellular response to organonitrogen compound GO:0071417 145 0.016
regulation of lamellipodium morphogenesis GO:2000392 1 0.016
positive regulation of nucleotide metabolic process GO:0045981 114 0.016
proteasomal protein catabolic process GO:0010498 98 0.016
regulation of syncytium formation by plasma membrane fusion GO:0060142 23 0.016
glycoprotein metabolic process GO:0009100 116 0.016
regulation of mitotic cell cycle GO:0007346 126 0.016
movement in host environment GO:0052126 15 0.016
organic hydroxy compound biosynthetic process GO:1901617 77 0.016
negative regulation of protein maturation GO:1903318 79 0.016
heart contraction GO:0060047 93 0.016
multicellular organismal metabolic process GO:0044236 28 0.016
nitric oxide biosynthetic process GO:0006809 25 0.016
development of primary female sexual characteristics GO:0046545 73 0.015
mesenchyme development GO:0060485 152 0.015
positive regulation of hair follicle cell proliferation GO:0071338 1 0.015
negative regulation of mapk cascade GO:0043409 65 0.015
negative regulation of nervous system development GO:0051961 156 0.015
regulation of type i interferon mediated signaling pathway GO:0060338 7 0.015
regulation of transcription by galactose GO:0000409 1 0.015
regulation of t cell mediated cytotoxicity GO:0001914 18 0.015
activation of adenylate cyclase activity GO:0007190 4 0.015
protein processing GO:0016485 163 0.015
positive regulation of cell adhesion GO:0045785 80 0.015
development of primary sexual characteristics GO:0045137 143 0.015
engulfment of apoptotic cell GO:0043652 3 0.015
regulation of cell projection assembly GO:0060491 38 0.015
substrate adhesion dependent cell spreading GO:0034446 30 0.015
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 87 0.015
microtubule based process GO:0007017 236 0.015
type i interferon signaling pathway GO:0060337 10 0.015
interaction with host GO:0051701 22 0.015
actin filament branching GO:0090135 1 0.015
oogenesis GO:0048477 56 0.015
inner ear receptor cell development GO:0060119 39 0.015
keratinocyte proliferation GO:0043616 21 0.015
female gonad development GO:0008585 71 0.015
nucleoside triphosphate metabolic process GO:0009141 230 0.015
positive regulation of proteolysis GO:0045862 85 0.015
interleukin 4 mediated signaling pathway GO:0035771 2 0.015
entry into host GO:0044409 15 0.014
regulation of erk1 and erk2 cascade GO:0070372 71 0.014
i kappab kinase nf kappab signaling GO:0007249 85 0.014
regulation of protein targeting GO:1903533 61 0.014
regulation of purine nucleotide catabolic process GO:0033121 122 0.014
regulation of neuron death GO:1901214 134 0.014
oocyte anterior posterior axis specification GO:0007314 2 0.014
alpha beta t cell activation involved in immune response GO:0002287 31 0.014
positive regulation of peptidase activity GO:0010952 49 0.014
organic hydroxy compound transport GO:0015850 93 0.014
purine ribonucleotide biosynthetic process GO:0009152 59 0.014
cell fate commitment GO:0045165 210 0.014
negative regulation of cell projection organization GO:0031345 56 0.014
amine metabolic process GO:0009308 45 0.014
cyclic nucleotide biosynthetic process GO:0009190 44 0.014
regulation of nuclear division GO:0051783 56 0.014
negative regulation of transferase activity GO:0051348 85 0.014
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.014
cellular response to hormone stimulus GO:0032870 150 0.014
viral transcription GO:0019083 3 0.014
positive regulation of lamellipodium assembly GO:0010592 2 0.014
sphingolipid catabolic process GO:0030149 7 0.014
organophosphate biosynthetic process GO:0090407 122 0.014
positive regulation of adaptive immune response GO:0002821 61 0.014
intracellular receptor signaling pathway GO:0030522 74 0.014
establishment of endothelial barrier GO:0061028 5 0.014
cd4 positive alpha beta t cell differentiation GO:0043367 41 0.014
ribonucleoside catabolic process GO:0042454 206 0.014
purine nucleotide metabolic process GO:0006163 302 0.014
morphogenesis of embryonic epithelium GO:0016331 159 0.013
interleukin 8 production GO:0032637 4 0.013
organophosphate catabolic process GO:0046434 232 0.013
regulation of cell cycle GO:0051726 281 0.013
lipid localization GO:0010876 126 0.013
viral life cycle GO:0019058 36 0.013
antigen processing and presentation of endogenous peptide antigen via mhc class i GO:0019885 3 0.013
natural killer cell mediated cytotoxicity GO:0042267 29 0.013
regulation of purine nucleotide biosynthetic process GO:1900371 34 0.013
regulation of peptidyl tyrosine phosphorylation GO:0050730 93 0.013
response to nutrient levels GO:0031667 109 0.013
multi multicellular organism process GO:0044706 109 0.013
cellular response to dna damage stimulus GO:0006974 207 0.013
regulation of endopeptidase activity GO:0052548 89 0.013
myd88 dependent toll like receptor signaling pathway GO:0002755 7 0.013
positive regulation of reactive oxygen species metabolic process GO:2000379 11 0.013

Shisa5 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.110
lysosomal storage disease DOID:3211 0 0.110
inherited metabolic disorder DOID:655 0 0.110
immune system disease DOID:2914 0 0.097
disease of anatomical entity DOID:7 0 0.097
lipid storage disease DOID:9455 0 0.063
central nervous system disease DOID:331 0 0.044
nervous system disease DOID:863 0 0.044
sphingolipidosis DOID:1927 0 0.028