Mus musculus

0 known processes

Iscu

IscU iron-sulfur cluster scaffold homolog (E. coli)

(Aliases: Nifun,Nifu,2310020H20Rik,AA407971)

Iscu biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
negative regulation of oxidative stress induced intrinsic apoptotic signaling pathway GO:1902176 4 0.118
cofactor metabolic process GO:0051186 80 0.094
regulation of ion transport GO:0043269 215 0.064
regulation of cellular ketone metabolic process GO:0010565 66 0.056
regulation of cellular amino acid metabolic process GO:0006521 5 0.042
negative regulation of cellular protein metabolic process GO:0032269 247 0.041
protein modification by small protein conjugation or removal GO:0070647 207 0.038
oxidation reduction process GO:0055114 342 0.037
cellular amino acid metabolic process GO:0006520 103 0.037
cation transport GO:0006812 399 0.037
negative regulation of intracellular signal transduction GO:1902532 167 0.032
regulation of mitochondrial fission GO:0090140 3 0.032
camera type eye development GO:0043010 266 0.029
reactive oxygen species metabolic process GO:0072593 84 0.029
cellular ketone metabolic process GO:0042180 84 0.028
response to radiation GO:0009314 165 0.027
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.023
regulation of transmembrane transport GO:0034762 128 0.023
cellular response to lipopolysaccharide GO:0071222 77 0.022
transmembrane transport GO:0055085 412 0.022
nucleobase containing small molecule metabolic process GO:0055086 352 0.022
nucleosome disassembly GO:0006337 1 0.021
cation homeostasis GO:0055080 212 0.021
fat cell differentiation GO:0045444 160 0.021
cellular amine metabolic process GO:0044106 44 0.020
spermatogenesis GO:0007283 284 0.020
adiponectin activated signaling pathway GO:0033211 4 0.020
protein ubiquitination GO:0016567 171 0.019
amine metabolic process GO:0009308 45 0.019
positive regulation of protein modification process GO:0031401 299 0.019
cation transmembrane transport GO:0098655 266 0.019
negative regulation of protein metabolic process GO:0051248 282 0.019
cellular response to lipid GO:0071396 145 0.019
peptidyl amino acid modification GO:0018193 336 0.018
regulation of reactive oxygen species metabolic process GO:2000377 40 0.018
mitochondrion degradation GO:0000422 3 0.018
apoptotic signaling pathway GO:0097190 306 0.018
metal ion homeostasis GO:0055065 189 0.017
positive regulation of cellular amine metabolic process GO:0033240 5 0.017
positive regulation of protein phosphorylation GO:0001934 242 0.017
regulation of transferase activity GO:0051338 263 0.017
leukocyte migration GO:0050900 124 0.016
cellular lipid metabolic process GO:0044255 323 0.016
cellular response to molecule of bacterial origin GO:0071219 83 0.016
organic acid biosynthetic process GO:0016053 86 0.016
neuron death GO:0070997 154 0.016
t helper 17 cell chemotaxis GO:0035705 1 0.016
negative regulation of protein modification process GO:0031400 163 0.016
regulation of cellular amine metabolic process GO:0033238 20 0.016
xenobiotic catabolic process GO:0042178 1 0.016
microtubule based process GO:0007017 236 0.015
cellular response to cytokine stimulus GO:0071345 189 0.015
mitochondrion organization GO:0007005 134 0.014
intrinsic apoptotic signaling pathway in response to oxidative stress GO:0008631 19 0.014
protein catabolic process GO:0030163 221 0.014
nitrobenzene metabolic process GO:0018916 1 0.014
dephosphorylation GO:0016311 129 0.014
inorganic cation transmembrane transport GO:0098662 207 0.014
ion transmembrane transport GO:0034220 361 0.014
carboxylic acid biosynthetic process GO:0046394 86 0.014
myeloid cell differentiation GO:0030099 233 0.013
inflammatory response GO:0006954 244 0.013
germ cell development GO:0007281 185 0.013
negative regulation of molecular function GO:0044092 258 0.013
male gamete generation GO:0048232 285 0.013
positive regulation of voltage gated calcium channel activity GO:1901387 2 0.013
regulation of apoptotic signaling pathway GO:2001233 197 0.013
cellular response to biotic stimulus GO:0071216 92 0.013
oocyte axis specification GO:0007309 2 0.013
inorganic ion transmembrane transport GO:0098660 234 0.013
regulation of ion transmembrane transport GO:0034765 119 0.013
neuron apoptotic process GO:0051402 142 0.013
sensory perception GO:0007600 245 0.013
negative regulation of apoptotic signaling pathway GO:2001234 104 0.013
protein modification by small protein conjugation GO:0032446 187 0.013
response to acid chemical GO:0001101 111 0.013
macromolecule catabolic process GO:0009057 281 0.012
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.012
chemotaxis GO:0006935 247 0.012
homeostasis of number of cells GO:0048872 210 0.012
posttranscriptional regulation of gene expression GO:0010608 155 0.012
regulation of defense response GO:0031347 233 0.012
regulation of protein maturation GO:1903317 96 0.012
organonitrogen compound biosynthetic process GO:1901566 192 0.012
spermatid development GO:0007286 108 0.012
epithelial cell development GO:0002064 159 0.012
negative regulation of cellular response to oxidative stress GO:1900408 10 0.012
proteasomal protein catabolic process GO:0010498 98 0.012
actin cytoskeleton organization GO:0030036 220 0.012
regulation of multi organism process GO:0043900 111 0.012
regulation of dopamine secretion GO:0014059 9 0.012
response to oxidative stress GO:0006979 123 0.012
negative regulation of protein phosphorylation GO:0001933 126 0.011
negative regulation of intrinsic apoptotic signaling pathway GO:2001243 34 0.011
regulation of cellular response to stress GO:0080135 159 0.011
cellular response to acid chemical GO:0071229 68 0.011
nucleoside phosphate metabolic process GO:0006753 338 0.011
digestive system development GO:0055123 200 0.011
sodium ion transmembrane transport GO:0035725 49 0.011
small molecule biosynthetic process GO:0044283 132 0.011
regulation of protein processing GO:0070613 96 0.011
muscle cell differentiation GO:0042692 261 0.011
interspecies interaction between organisms GO:0044419 83 0.011
defense response to bacterium GO:0042742 119 0.011
negative regulation of immune system process GO:0002683 209 0.011
response to organic cyclic compound GO:0014070 198 0.011
developmental growth involved in morphogenesis GO:0060560 138 0.011
cytokine production GO:0001816 319 0.010
multi multicellular organism process GO:0044706 109 0.010
oocyte construction GO:0007308 2 0.010
multicellular organismal homeostasis GO:0048871 164 0.010
spermatid differentiation GO:0048515 115 0.010
defense response to other organism GO:0098542 197 0.010
ubiquitin dependent protein catabolic process GO:0006511 129 0.010
regulation of neuron death GO:1901214 134 0.010
synaptic transmission GO:0007268 329 0.010

Iscu disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.039
nervous system disease DOID:863 0 0.039
sensory system disease DOID:0050155 0 0.022
eye and adnexa disease DOID:1492 0 0.020
central nervous system disease DOID:331 0 0.014