Mus musculus

0 known processes

Spink8

serine peptidase inhibitor, Kazal type 8

(Aliases: C630041L24Rik)

Spink8 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
ion transmembrane transport GO:0034220 361 0.073
transmembrane transport GO:0055085 412 0.063
cation transport GO:0006812 399 0.054
cellular amino acid metabolic process GO:0006520 103 0.054
inorganic ion transmembrane transport GO:0098660 234 0.052
cellular ketone metabolic process GO:0042180 84 0.046
cation transmembrane transport GO:0098655 266 0.044
amine metabolic process GO:0009308 45 0.041
inorganic cation transmembrane transport GO:0098662 207 0.038
cellular amine metabolic process GO:0044106 44 0.037
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.036
regulation of cellular amine metabolic process GO:0033238 20 0.032
nucleobase containing small molecule metabolic process GO:0055086 352 0.031
regulation of cellular amino acid metabolic process GO:0006521 5 0.030
carboxylic acid transport GO:0046942 100 0.029
oxidation reduction process GO:0055114 342 0.029
apoptotic signaling pathway GO:0097190 306 0.028
single organism cell adhesion GO:0098602 156 0.027
peptidyl amino acid modification GO:0018193 336 0.026
positive regulation of cellular amine metabolic process GO:0033240 5 0.026
anion transport GO:0006820 177 0.025
cation homeostasis GO:0055080 212 0.025
intracellular protein transport GO:0006886 204 0.024
cytokine production GO:0001816 319 0.024
regulation of cellular ketone metabolic process GO:0010565 66 0.024
skeletal muscle organ development GO:0060538 163 0.023
protein modification by small protein conjugation or removal GO:0070647 207 0.023
mitotic cell cycle GO:0000278 195 0.023
sensory perception GO:0007600 245 0.023
purine nucleotide metabolic process GO:0006163 302 0.023
regulation of cell activation GO:0050865 289 0.022
organic anion transport GO:0015711 137 0.022
purine nucleoside metabolic process GO:0042278 241 0.022
positive regulation of protein modification process GO:0031401 299 0.022
macromolecule catabolic process GO:0009057 281 0.022
male gamete generation GO:0048232 285 0.022
regulation of protein localization GO:0032880 231 0.022
negative regulation of phosphorus metabolic process GO:0010563 184 0.022
g protein coupled receptor signaling pathway GO:0007186 243 0.021
anatomical structure homeostasis GO:0060249 145 0.021
purine containing compound metabolic process GO:0072521 311 0.021
response to organic cyclic compound GO:0014070 198 0.021
spermatogenesis GO:0007283 284 0.021
carbohydrate metabolic process GO:0005975 230 0.021
response to organonitrogen compound GO:0010243 246 0.021
protein maturation GO:0051604 176 0.020
monocarboxylic acid metabolic process GO:0032787 191 0.020
regulation of secretion by cell GO:1903530 249 0.020
organonitrogen compound biosynthetic process GO:1901566 192 0.020
membrane organization GO:0061024 245 0.020
nucleotide metabolic process GO:0009117 332 0.020
nitrogen compound transport GO:0071705 271 0.020
negative regulation of immune system process GO:0002683 209 0.020
regulation of organelle organization GO:0033043 289 0.020
negative regulation of phosphate metabolic process GO:0045936 184 0.020
ribonucleotide metabolic process GO:0009259 291 0.019
mitotic cell cycle process GO:1903047 159 0.019
aromatic compound catabolic process GO:0019439 286 0.019
regulation of cellular catabolic process GO:0031329 242 0.019
regulation of hormone levels GO:0010817 211 0.019
nucleoside phosphate metabolic process GO:0006753 338 0.019
cofactor metabolic process GO:0051186 80 0.019
myotube differentiation GO:0014902 105 0.019
regulation of establishment of protein localization GO:0070201 181 0.019
cytoplasmic transport GO:0016482 234 0.018
ribonucleoside metabolic process GO:0009119 245 0.018
regulation of hydrolase activity GO:0051336 246 0.018
single organismal cell cell adhesion GO:0016337 131 0.018
protein localization to organelle GO:0033365 185 0.018
sulfur compound metabolic process GO:0006790 100 0.018
regulation of protein transport GO:0051223 163 0.018
striated muscle tissue development GO:0014706 293 0.018
small gtpase mediated signal transduction GO:0007264 97 0.018
regulation of ion transmembrane transport GO:0034765 119 0.017
cellular alcohol metabolic process GO:0044107 3 0.017
nucleoside metabolic process GO:0009116 246 0.017
multicellular organismal signaling GO:0035637 91 0.017
regulation of lymphocyte activation GO:0051249 240 0.017
nucleoside catabolic process GO:0009164 206 0.017
negative regulation of phosphorylation GO:0042326 166 0.017
leukocyte differentiation GO:0002521 342 0.017
anion transmembrane transport GO:0098656 71 0.017
reactive oxygen species metabolic process GO:0072593 84 0.017
ribose phosphate metabolic process GO:0019693 291 0.017
glycosyl compound metabolic process GO:1901657 246 0.017
regulation of cellular component biogenesis GO:0044087 181 0.016
cell adhesion GO:0007155 329 0.016
carbohydrate derivative catabolic process GO:1901136 231 0.016
regulation of metal ion transport GO:0010959 106 0.016
negative regulation of protein metabolic process GO:0051248 282 0.016
organic cyclic compound catabolic process GO:1901361 295 0.016
cellular nitrogen compound catabolic process GO:0044270 280 0.016
protein modification by small protein conjugation GO:0032446 187 0.016
purine ribonucleotide metabolic process GO:0009150 290 0.016
regulation of cytokine production GO:0001817 266 0.016
protein processing GO:0016485 163 0.016
protein catabolic process GO:0030163 221 0.016
regulation of reactive oxygen species metabolic process GO:2000377 40 0.016
amino acid transport GO:0006865 61 0.016
fat cell differentiation GO:0045444 160 0.016
cellular alcohol biosynthetic process GO:0044108 3 0.016
reactive nitrogen species metabolic process GO:2001057 0 0.016
regulation of intracellular transport GO:0032386 159 0.016
cellular response to cytokine stimulus GO:0071345 189 0.016
mapk cascade GO:0000165 281 0.016
negative regulation of molecular function GO:0044092 258 0.016
organelle fission GO:0048285 170 0.016
maintenance of location GO:0051235 89 0.015
regulation of ion transport GO:0043269 215 0.015
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.015
muscle cell differentiation GO:0042692 261 0.015
synaptic transmission GO:0007268 329 0.015
nuclear division GO:0000280 158 0.015
small molecule biosynthetic process GO:0044283 132 0.015
regulation of membrane potential GO:0042391 192 0.015
positive regulation of protein phosphorylation GO:0001934 242 0.015
purine ribonucleoside metabolic process GO:0046128 241 0.015
organophosphate catabolic process GO:0046434 232 0.015
carbohydrate derivative biosynthetic process GO:1901137 183 0.015
reactive oxygen species biosynthetic process GO:1903409 8 0.015
protein ubiquitination GO:0016567 171 0.015
regulation of secretion GO:0051046 274 0.014
potassium ion homeostasis GO:0055075 4 0.014
respiratory system development GO:0060541 190 0.014
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.014
hematopoietic progenitor cell differentiation GO:0002244 143 0.014
purine nucleoside catabolic process GO:0006152 205 0.014
cellular metal ion homeostasis GO:0006875 151 0.014
gland development GO:0048732 330 0.014
cellular lipid metabolic process GO:0044255 323 0.014
cellular response to organonitrogen compound GO:0071417 145 0.014
purine nucleoside triphosphate metabolic process GO:0009144 226 0.014
protein targeting GO:0006605 143 0.014
positive regulation of apoptotic process GO:0043065 217 0.014
divalent metal ion transport GO:0070838 172 0.014
regulation of cell cycle process GO:0010564 160 0.014
regulation of transmembrane transport GO:0034762 128 0.014
microtubule based process GO:0007017 236 0.013
inter male aggressive behavior GO:0002121 3 0.013
multicellular organismal homeostasis GO:0048871 164 0.013
cellular protein catabolic process GO:0044257 155 0.013
negative regulation of mapk cascade GO:0043409 65 0.013
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.013
response to radiation GO:0009314 165 0.013
divalent inorganic cation transport GO:0072511 178 0.013
ribonucleoside triphosphate metabolic process GO:0009199 220 0.013
negative regulation of cellular component organization GO:0051129 194 0.013
cellular protein complex assembly GO:0043623 116 0.013
multi multicellular organism process GO:0044706 109 0.013
chemotaxis GO:0006935 247 0.013
ribonucleoside triphosphate catabolic process GO:0009203 199 0.013
blood circulation GO:0008015 195 0.013
lymphocyte differentiation GO:0030098 242 0.013
cellular ion homeostasis GO:0006873 165 0.013
renal system development GO:0072001 225 0.013
purine ribonucleoside catabolic process GO:0046130 205 0.013
regulation of apoptotic signaling pathway GO:2001233 197 0.013
negative regulation of cell proliferation GO:0008285 296 0.013
purine containing compound catabolic process GO:0072523 213 0.013
regulation of cell cycle GO:0051726 281 0.013
response to extracellular stimulus GO:0009991 127 0.013
heterocycle catabolic process GO:0046700 280 0.013
metal ion homeostasis GO:0055065 189 0.013
positive regulation of kinase activity GO:0033674 155 0.013
negative regulation of cellular amine metabolic process GO:0033239 1 0.013
regulation of homeostatic process GO:0032844 182 0.012
negative regulation of intracellular signal transduction GO:1902532 167 0.012
response to peptide GO:1901652 136 0.012
muscle tissue development GO:0060537 308 0.012
potassium ion transport GO:0006813 52 0.012
dna metabolic process GO:0006259 303 0.012
regulation of purine nucleotide metabolic process GO:1900542 169 0.012
ribonucleoside catabolic process GO:0042454 206 0.012
nucleoside triphosphate metabolic process GO:0009141 230 0.012
dephosphorylation GO:0016311 129 0.012
locomotory behavior GO:0007626 195 0.012
response to molecule of bacterial origin GO:0002237 143 0.012
ras protein signal transduction GO:0007265 77 0.012
cellular macromolecule catabolic process GO:0044265 206 0.012
cellular response to hormone stimulus GO:0032870 150 0.012
rhythmic process GO:0048511 174 0.012
regulation of cell migration GO:0030334 219 0.012
sodium ion transport GO:0006814 73 0.012
establishment of protein localization to organelle GO:0072594 118 0.012
positive regulation of cell development GO:0010720 237 0.012
negative regulation of cell development GO:0010721 169 0.012
cellular divalent inorganic cation homeostasis GO:0072503 127 0.012
regulation of ion homeostasis GO:2000021 64 0.012
urogenital system development GO:0001655 261 0.012
circulatory system process GO:0003013 197 0.012
endocytosis GO:0006897 168 0.012
cellular homeostasis GO:0019725 240 0.012
organic acid transport GO:0015849 101 0.012
engulfment of apoptotic cell GO:0043652 3 0.012
spermatid development GO:0007286 108 0.012
regulation of proteolysis GO:0030162 164 0.012
response to peptide hormone GO:0043434 127 0.012
regulation of multi organism process GO:0043900 111 0.012
regulation of striated muscle cell differentiation GO:0051153 81 0.012
cellular response to dna damage stimulus GO:0006974 207 0.012
cellular response to lipid GO:0071396 145 0.012
organophosphate biosynthetic process GO:0090407 122 0.012
sequestering of calcium ion GO:0051208 18 0.012
purine nucleotide catabolic process GO:0006195 211 0.012
spermatid differentiation GO:0048515 115 0.012
feeding behavior GO:0007631 62 0.012
midgut development GO:0007494 4 0.011
regulation of cell motility GO:2000145 236 0.011
leukocyte migration GO:0050900 124 0.011
b cell activation GO:0042113 161 0.011
organonitrogen compound catabolic process GO:1901565 264 0.011
regulation of leukocyte differentiation GO:1902105 159 0.011
regulation of feeding behavior GO:0060259 3 0.011
tissue homeostasis GO:0001894 115 0.011
positive regulation of cell death GO:0010942 224 0.011
nuclear transport GO:0051169 139 0.011
positive regulation of transferase activity GO:0051347 167 0.011
positive regulation of programmed cell death GO:0043068 218 0.011
calcium ion transmembrane transport GO:0070588 85 0.011
regulation of blood pressure GO:0008217 93 0.011
protein secretion GO:0009306 111 0.011
immune effector process GO:0002252 321 0.011
positive regulation of leukocyte differentiation GO:1902107 86 0.011
erk1 and erk2 cascade GO:0070371 77 0.011
skin development GO:0043588 220 0.011
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.011
wnt signaling pathway GO:0016055 188 0.011
innate immune response GO:0045087 157 0.011
nucleoside phosphate catabolic process GO:1901292 222 0.011
positive regulation of protein kinase activity GO:0045860 144 0.011
negative regulation of cell cycle GO:0045786 123 0.011
positive regulation of hydrolase activity GO:0051345 148 0.011
steroid metabolic process GO:0008202 119 0.011
divalent inorganic cation homeostasis GO:0072507 138 0.011
skeletal muscle fiber development GO:0048741 58 0.011
negative regulation of homeostatic process GO:0032845 71 0.011
peptidyl serine phosphorylation GO:0018105 74 0.011
t cell activation GO:0042110 289 0.011
cytokine mediated signaling pathway GO:0019221 115 0.011
negative regulation of cellular protein metabolic process GO:0032269 247 0.011
calcium ion transport GO:0006816 159 0.011
muscle contraction GO:0006936 101 0.011
meiotic nuclear division GO:0007126 115 0.011
coenzyme metabolic process GO:0006732 52 0.011
positive regulation of lymphocyte activation GO:0051251 140 0.011
peptidyl tyrosine phosphorylation GO:0018108 143 0.010
interleukin 8 production GO:0032637 4 0.010
regulation of muscle tissue development GO:1901861 97 0.010
oocyte construction GO:0007308 2 0.010
nucleocytoplasmic transport GO:0006913 139 0.010
carbohydrate biosynthetic process GO:0016051 74 0.010
mitochondrion organization GO:0007005 134 0.010
microtubule cytoskeleton organization GO:0000226 157 0.010
intrinsic apoptotic signaling pathway GO:0097193 132 0.010
response to lipopolysaccharide GO:0032496 128 0.010
axonogenesis GO:0007409 274 0.010
regulation of transferase activity GO:0051338 263 0.010
negative regulation of protein modification process GO:0031400 163 0.010
positive regulation of striated muscle contraction GO:0045989 3 0.010
peptidyl serine modification GO:0018209 83 0.010
positive regulation of cell activation GO:0050867 158 0.010
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.010
blood vessel morphogenesis GO:0048514 285 0.010
regulation of neuron differentiation GO:0045664 281 0.010
organic hydroxy compound metabolic process GO:1901615 203 0.010
meiotic cell cycle GO:0051321 122 0.010
regulation of system process GO:0044057 200 0.010
regulation of cell projection organization GO:0031344 206 0.010
glycosyl compound catabolic process GO:1901658 206 0.010
regulation of cell adhesion GO:0030155 154 0.010

Spink8 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.018
nervous system disease DOID:863 0 0.018
disease of metabolism DOID:0014667 0 0.017
musculoskeletal system disease DOID:17 0 0.012
cancer DOID:162 0 0.011
disease of cellular proliferation DOID:14566 0 0.011
organ system cancer DOID:0050686 0 0.011
inherited metabolic disorder DOID:655 0 0.011
immune system disease DOID:2914 0 0.011
connective tissue disease DOID:65 0 0.011