Mus musculus

0 known processes

Spink4

serine peptidase inhibitor, Kazal type 4

(Aliases: MPGC60)

Spink4 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
inflammatory response GO:0006954 244 0.139
developmental growth involved in morphogenesis GO:0060560 138 0.129
regulation of cytokine production GO:0001817 266 0.114
positive regulation of defense response GO:0031349 124 0.111
lipid homeostasis GO:0055088 63 0.104
regulation of kinase activity GO:0043549 249 0.103
cholesterol transport GO:0030301 38 0.101
germ cell development GO:0007281 185 0.093
Mouse
regulation of protein kinase activity GO:0045859 232 0.088
sterol homeostasis GO:0055092 45 0.088
t cell differentiation GO:0030217 174 0.085
anion transport GO:0006820 177 0.084
adaptive immune response GO:0002250 155 0.080
regulation of lymphocyte activation GO:0051249 240 0.080
humoral immune response GO:0006959 57 0.077
cellular macromolecule catabolic process GO:0044265 206 0.077
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.076
negative regulation of cellular amine metabolic process GO:0033239 1 0.076
regulation of inflammatory response GO:0050727 147 0.075
regulation of innate immune response GO:0045088 91 0.074
nitrogen compound transport GO:0071705 271 0.074
negative regulation of phosphorylation GO:0042326 166 0.073
positive regulation of protein phosphorylation GO:0001934 242 0.073
purine nucleoside metabolic process GO:0042278 241 0.072
organic cyclic compound catabolic process GO:1901361 295 0.071
chemotaxis GO:0006935 247 0.069
alcohol metabolic process GO:0006066 116 0.068
lymphocyte differentiation GO:0030098 242 0.068
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.068
negative regulation of cellular protein metabolic process GO:0032269 247 0.065
Mouse
negative regulation of defense response GO:0031348 77 0.064
regulation of defense response GO:0031347 233 0.063
cholesterol metabolic process GO:0008203 56 0.062
cytokine production GO:0001816 319 0.062
negative regulation of immune system process GO:0002683 209 0.062
negative regulation of protein metabolic process GO:0051248 282 0.061
Mouse
cholesterol homeostasis GO:0042632 44 0.061
regulation of transferase activity GO:0051338 263 0.060
multi multicellular organism process GO:0044706 109 0.060
sterol transport GO:0015918 38 0.060
heterocycle catabolic process GO:0046700 280 0.059
cellular amine metabolic process GO:0044106 44 0.056
skeletal system development GO:0001501 356 0.056
spermatogenesis GO:0007283 284 0.055
Mouse
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.055
regulation of cellular ketone metabolic process GO:0010565 66 0.055
regulation of cellular amino acid metabolic process GO:0006521 5 0.054
cellular protein complex assembly GO:0043623 116 0.054
regulation of cellular amine metabolic process GO:0033238 20 0.054
defense response to bacterium GO:0042742 119 0.052
regulation of cell motility GO:2000145 236 0.051
Mouse
regulation of lymphocyte differentiation GO:0045619 107 0.051
lipid transport GO:0006869 98 0.051
ribonucleoside triphosphate metabolic process GO:0009199 220 0.051
molting cycle GO:0042303 90 0.050
regulation of neuron differentiation GO:0045664 281 0.050
gliogenesis GO:0042063 141 0.050
negative regulation of protein phosphorylation GO:0001933 126 0.050
cellular nitrogen compound catabolic process GO:0044270 280 0.050
sterol metabolic process GO:0016125 58 0.049
action potential GO:0001508 78 0.044
cytoplasmic transport GO:0016482 234 0.044
fertilization GO:0009566 127 0.044
Mouse
positive regulation of innate immune response GO:0045089 80 0.042
posttranscriptional regulation of gene expression GO:0010608 155 0.042
protein ubiquitination GO:0016567 171 0.042
activation of immune response GO:0002253 138 0.041
t helper 2 cell cytokine production GO:0035745 4 0.041
macromolecule catabolic process GO:0009057 281 0.041
lipid localization GO:0010876 126 0.040
response to oxidative stress GO:0006979 123 0.040
epithelial cell proliferation GO:0050673 174 0.040
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.040
protein modification by small protein conjugation GO:0032446 187 0.040
regulation of body fluid levels GO:0050878 162 0.039
neutral lipid metabolic process GO:0006638 57 0.039
morphogenesis of a branching structure GO:0001763 203 0.039
regulation of t cell differentiation GO:0045580 83 0.039
protein modification by small protein conjugation or removal GO:0070647 207 0.038
immune effector process GO:0002252 321 0.038
organic anion transport GO:0015711 137 0.038
steroid metabolic process GO:0008202 119 0.038
transmission of nerve impulse GO:0019226 76 0.038
t helper cell differentiation GO:0042093 28 0.037
negative regulation of cell proliferation GO:0008285 296 0.037
cellular response to starvation GO:0009267 57 0.037
positive regulation of protein modification process GO:0031401 299 0.037
negative regulation of phosphorus metabolic process GO:0010563 184 0.036
leukocyte activation involved in immune response GO:0002366 126 0.036
regulation of cellular catabolic process GO:0031329 242 0.036
intestinal absorption GO:0050892 13 0.036
leukocyte proliferation GO:0070661 172 0.036
ribose phosphate metabolic process GO:0019693 291 0.035
carbohydrate derivative catabolic process GO:1901136 231 0.035
cation transport GO:0006812 399 0.035
translation GO:0006412 93 0.034
peptidyl tyrosine phosphorylation GO:0018108 143 0.034
cellular amino acid metabolic process GO:0006520 103 0.034
response to monosaccharide GO:0034284 67 0.034
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 87 0.033
cell adhesion GO:0007155 329 0.033
muscle cell differentiation GO:0042692 261 0.033
male gamete generation GO:0048232 285 0.033
Mouse
cd4 positive alpha beta t cell differentiation GO:0043367 41 0.033
organic hydroxy compound metabolic process GO:1901615 203 0.033
negative regulation of cell development GO:0010721 169 0.032
Mouse
regulation of hydrolase activity GO:0051336 246 0.032
Mouse
axonogenesis GO:0007409 274 0.032
glycoprotein metabolic process GO:0009100 116 0.032
blastocyst development GO:0001824 80 0.032
regulation of cellular response to stress GO:0080135 159 0.031
stem cell development GO:0048864 219 0.031
nucleoside triphosphate metabolic process GO:0009141 230 0.031
positive regulation of cell activation GO:0050867 158 0.031
nucleoside metabolic process GO:0009116 246 0.031
cellular chemical homeostasis GO:0055082 215 0.031
axon guidance GO:0007411 141 0.031
regulation of mapk cascade GO:0043408 248 0.031
positive regulation of cellular amine metabolic process GO:0033240 5 0.031
t cell activation GO:0042110 289 0.031
response to organic cyclic compound GO:0014070 198 0.031
striated muscle cell development GO:0055002 125 0.030
apoptotic signaling pathway GO:0097190 306 0.030
nucleotide metabolic process GO:0009117 332 0.030
antimicrobial peptide production GO:0002775 2 0.030
peptidyl amino acid modification GO:0018193 336 0.030
g protein coupled receptor signaling pathway GO:0007186 243 0.030
glycosyl compound metabolic process GO:1901657 246 0.029
response to organonitrogen compound GO:0010243 246 0.029
positive regulation of programmed cell death GO:0043068 218 0.029
cellular ketone metabolic process GO:0042180 84 0.029
positive regulation of response to wounding GO:1903036 66 0.029
striated muscle tissue development GO:0014706 293 0.029
lymphocyte activation involved in immune response GO:0002285 93 0.028
regulation of cell projection organization GO:0031344 206 0.028
gland development GO:0048732 330 0.028
ribonucleoside metabolic process GO:0009119 245 0.028
liver development GO:0001889 66 0.028
negative regulation of sterol transport GO:0032372 4 0.027
regulation of epithelial cell proliferation GO:0050678 141 0.027
regulation of cholesterol transport GO:0032374 17 0.027
response to oxygen levels GO:0070482 62 0.027
cd4 positive alpha beta t cell activation GO:0035710 45 0.027
lipid modification GO:0030258 65 0.027
protein maturation GO:0051604 176 0.027
Mouse
leukocyte mediated immunity GO:0002443 174 0.026
negative regulation of inflammatory response GO:0050728 61 0.026
purine ribonucleoside metabolic process GO:0046128 241 0.026
regulation of membrane potential GO:0042391 192 0.026
mature dendritic cell differentiation GO:0097029 3 0.026
actomyosin structure organization GO:0031032 56 0.026
cellular ion homeostasis GO:0006873 165 0.026
carbohydrate homeostasis GO:0033500 128 0.026
neuronal action potential GO:0019228 54 0.026
regulation of cell cycle GO:0051726 281 0.025
cell growth GO:0016049 130 0.025
purine ribonucleoside catabolic process GO:0046130 205 0.025
organelle fission GO:0048285 170 0.025
positive regulation of secretion GO:0051047 130 0.024
ventral trunk neural crest cell migration GO:0036486 4 0.024
keratinocyte differentiation GO:0030216 48 0.024
nucleobase containing small molecule metabolic process GO:0055086 352 0.024
regulation of chemotaxis GO:0050920 53 0.024
skeletal muscle organ development GO:0060538 163 0.024
glucose homeostasis GO:0042593 128 0.024
nucleic acid phosphodiester bond hydrolysis GO:0090305 49 0.024
protein targeting GO:0006605 143 0.024
negative regulation of protein modification process GO:0031400 163 0.023
regulation of cell migration GO:0030334 219 0.023
response to extracellular stimulus GO:0009991 127 0.023
purine containing compound metabolic process GO:0072521 311 0.023
negative regulation of molecular function GO:0044092 258 0.023
Mouse
cellular response to extracellular stimulus GO:0031668 81 0.023
regulation of t cell activation GO:0050863 170 0.023
cell type specific apoptotic process GO:0097285 268 0.023
nephron tubule development GO:0072080 84 0.023
purine ribonucleotide metabolic process GO:0009150 290 0.023
glycoprotein biosynthetic process GO:0009101 89 0.023
cellular response to organonitrogen compound GO:0071417 145 0.023
rna catabolic process GO:0006401 29 0.023
negative regulation of phosphate metabolic process GO:0045936 184 0.023
regulation of interleukin 2 production GO:0032663 28 0.023
alpha beta t cell differentiation GO:0046632 69 0.023
meiotic cell cycle GO:0051321 122 0.023
positive regulation of apoptotic process GO:0043065 217 0.022
regulation of translation GO:0006417 71 0.022
endomembrane system organization GO:0010256 147 0.022
negative regulation of cytokine production GO:0001818 84 0.022
cellular response to growth factor stimulus GO:0071363 197 0.022
regulation of protein processing GO:0070613 96 0.022
Mouse
regulation of intrinsic apoptotic signaling pathway GO:2001242 61 0.022
embryonic epithelial tube formation GO:0001838 130 0.022
defense response to other organism GO:0098542 197 0.022
striated muscle myosin thick filament assembly GO:0071688 1 0.022
secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development GO:0060528 4 0.021
positive regulation of t cell activation GO:0050870 101 0.021
positive regulation of epithelial cell proliferation GO:0050679 68 0.021
myosin filament assembly GO:0031034 2 0.021
cellular component assembly involved in morphogenesis GO:0010927 139 0.021
negative regulation of cell migration GO:0030336 59 0.021
cell cell recognition GO:0009988 44 0.021
nuclear division GO:0000280 158 0.021
regulation of leukocyte mediated immunity GO:0002703 104 0.021
myosin filament organization GO:0031033 3 0.021
hepaticobiliary system development GO:0061008 67 0.021
glycerolipid metabolic process GO:0046486 122 0.021
morphogenesis of a branching epithelium GO:0061138 193 0.021
purine nucleoside triphosphate catabolic process GO:0009146 203 0.021
negative regulation of cell activation GO:0050866 111 0.021
positive regulation of lymphocyte activation GO:0051251 140 0.021
regulation of peptide transport GO:0090087 91 0.020
aromatic compound catabolic process GO:0019439 286 0.020
regulation of purine nucleotide catabolic process GO:0033121 122 0.020
stem cell differentiation GO:0048863 268 0.020
regulation of organ morphogenesis GO:2000027 144 0.020
skin development GO:0043588 220 0.020
cytokine mediated signaling pathway GO:0019221 115 0.020
response to vitamin a GO:0033189 1 0.020
cytokine metabolic process GO:0042107 71 0.020
intracellular protein transport GO:0006886 204 0.020
cellular protein catabolic process GO:0044257 155 0.020
lymphocyte mediated immunity GO:0002449 139 0.020
negative regulation of epithelial cell proliferation GO:0050680 64 0.020
developmental cell growth GO:0048588 84 0.020
regulation of multi organism process GO:0043900 111 0.020
Mouse
single fertilization GO:0007338 82 0.020
response to nutrient levels GO:0031667 109 0.020
leukocyte chemotaxis GO:0030595 69 0.019
leukocyte differentiation GO:0002521 342 0.019
negative regulation of protein maturation GO:1903318 79 0.019
Mouse
wnt signaling pathway GO:0016055 188 0.019
purine containing compound catabolic process GO:0072523 213 0.019
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.019
organic acid biosynthetic process GO:0016053 86 0.019
innate immune response GO:0045087 157 0.019
lipoprotein metabolic process GO:0042157 43 0.019
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.019
cellular potassium ion transport GO:0071804 43 0.019
positive regulation of antimicrobial peptide production GO:0002225 1 0.019
cellular response to transforming growth factor beta stimulus GO:0071560 88 0.019
neuron apoptotic process GO:0051402 142 0.019
maintenance of location GO:0051235 89 0.019
purine nucleoside catabolic process GO:0006152 205 0.018
regulation of secretion GO:0051046 274 0.018
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.018
regulation of epidermis development GO:0045682 33 0.018
positive regulation of cell development GO:0010720 237 0.018
alpha beta t cell differentiation involved in immune response GO:0002293 30 0.018
regulation of apoptotic signaling pathway GO:2001233 197 0.018
membrane organization GO:0061024 245 0.018
transmembrane transport GO:0055085 412 0.018
nucleoside triphosphate catabolic process GO:0009143 205 0.018
regulation of binding GO:0051098 111 0.018
cell activation involved in immune response GO:0002263 126 0.018
protein catabolic process GO:0030163 221 0.018
interleukin 1 beta production GO:0032611 30 0.018
leukocyte migration GO:0050900 124 0.018
regulation of feeding behavior GO:0060259 3 0.017
negative regulation of cholesterol transport GO:0032375 4 0.017
response to acid chemical GO:0001101 111 0.017
cholesterol efflux GO:0033344 24 0.017
regulation of cell activation GO:0050865 289 0.017
t cell differentiation in thymus GO:0033077 77 0.017
positive regulation of protein kinase activity GO:0045860 144 0.017
nucleoside catabolic process GO:0009164 206 0.017
myelination GO:0042552 74 0.017
regulation of cellular component biogenesis GO:0044087 181 0.017
hair cycle GO:0042633 90 0.017
cellular response to biotic stimulus GO:0071216 92 0.017
response to lipopolysaccharide GO:0032496 128 0.017
regulation of lymphocyte mediated immunity GO:0002706 84 0.017
protein processing GO:0016485 163 0.017
Mouse
alpha beta t cell activation GO:0046631 91 0.017
cellular response to external stimulus GO:0071496 88 0.017
neuron projection guidance GO:0097485 141 0.017
lymphocyte proliferation GO:0046651 164 0.017
immune response activating signal transduction GO:0002757 116 0.017
cellular response to nutrient levels GO:0031669 64 0.017
t cell activation involved in immune response GO:0002286 43 0.017
positive regulation of cytokine production GO:0001819 174 0.017
ubiquitin dependent protein catabolic process GO:0006511 129 0.017
blastocyst formation GO:0001825 33 0.016
cation homeostasis GO:0055080 212 0.016
amine metabolic process GO:0009308 45 0.016
regulation of proteolysis GO:0030162 164 0.016
Mouse
cellular metal ion homeostasis GO:0006875 151 0.016
amide transport GO:0042886 138 0.016
response to light stimulus GO:0009416 135 0.016
cd4 positive alpha beta t cell cytokine production GO:0035743 4 0.016
cellular homeostasis GO:0019725 240 0.016
organic hydroxy compound transport GO:0015850 93 0.016
regulation of reproductive process GO:2000241 66 0.016
Mouse
purine ribonucleotide catabolic process GO:0009154 208 0.016
spermatid development GO:0007286 108 0.016
Mouse
intrinsic apoptotic signaling pathway GO:0097193 132 0.016
regulation of morphogenesis of a branching structure GO:0060688 53 0.016
jak stat cascade GO:0007259 42 0.016
regulation of angiogenesis GO:0045765 81 0.015
respiratory system development GO:0060541 190 0.015
negative regulation of growth GO:0045926 99 0.015
positive regulation of secretion by cell GO:1903532 114 0.015
regulation of leukocyte proliferation GO:0070663 121 0.015
organ growth GO:0035265 117 0.015
regulation of t helper 2 cell cytokine production GO:2000551 3 0.015
regulation of adaptive immune response GO:0002819 90 0.015
regulation of leukocyte differentiation GO:1902105 159 0.015
negative regulation of immune effector process GO:0002698 55 0.015
positive regulation of inflammatory response GO:0050729 47 0.015
negative regulation of macrophage apoptotic process GO:2000110 3 0.015
positive regulation of stress activated mapk cascade GO:0032874 48 0.015
neuromuscular process GO:0050905 99 0.015
modification dependent macromolecule catabolic process GO:0043632 133 0.015
smoothened signaling pathway GO:0007224 105 0.015
innate immune response in mucosa GO:0002227 3 0.015
cellular response to cytokine stimulus GO:0071345 189 0.015
regulation of mitotic cell cycle GO:0007346 126 0.015
antimicrobial peptide biosynthetic process GO:0002777 2 0.015
nephron epithelium development GO:0072009 92 0.015
regulation of map kinase activity GO:0043405 120 0.015
positive regulation of immune effector process GO:0002699 107 0.015
telencephalon development GO:0021537 186 0.014
purine nucleotide metabolic process GO:0006163 302 0.014
acetate ester transport GO:1901374 2 0.014
b cell mediated immunity GO:0019724 71 0.014
carboxylic acid biosynthetic process GO:0046394 86 0.014
regulation of sterol transport GO:0032371 17 0.014
actin cytoskeleton organization GO:0030036 220 0.014
response to decreased oxygen levels GO:0036293 59 0.014
stress activated mapk cascade GO:0051403 80 0.014
regulation of cytokine biosynthetic process GO:0042035 59 0.014
organophosphate catabolic process GO:0046434 232 0.014
regulation of intracellular transport GO:0032386 159 0.014
rna processing GO:0006396 105 0.014
positive regulation of cellular catabolic process GO:0031331 148 0.014
peptide transport GO:0015833 133 0.014
glycosaminoglycan metabolic process GO:0030203 34 0.014
epithelial tube formation GO:0072175 130 0.014
regionalization GO:0003002 337 0.014
aminoglycan metabolic process GO:0006022 34 0.014
regulation of alpha beta t cell activation GO:0046634 53 0.014
regulation of neutrophil chemotaxis GO:0090022 14 0.014
positive regulation of lymphocyte proliferation GO:0050671 70 0.014
mammary gland epithelium development GO:0061180 65 0.014
negative regulation of prostatic bud formation GO:0060686 4 0.014
lipid biosynthetic process GO:0008610 179 0.014
regulation of response to wounding GO:1903034 189 0.014
lung development GO:0030324 164 0.014
nuclear import GO:0051170 95 0.014
branching morphogenesis of an epithelial tube GO:0048754 159 0.014
blood vessel morphogenesis GO:0048514 285 0.014
response to transforming growth factor beta GO:0071559 88 0.014
modification dependent protein catabolic process GO:0019941 133 0.014
regulation of vasculature development GO:1901342 88 0.014
mucopolysaccharide metabolic process GO:1903510 25 0.014
positive regulation of nucleoside metabolic process GO:0045979 91 0.013
regulation of protein maturation GO:1903317 96 0.013
Mouse
potassium ion transport GO:0006813 52 0.013
activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 3 0.013
trunk segmentation GO:0035290 4 0.013
renal tubule morphogenesis GO:0061333 72 0.013
cardiac muscle cell differentiation GO:0055007 69 0.013
camera type eye development GO:0043010 266 0.013
positive regulation of cell death GO:0010942 224 0.013
hindbrain development GO:0030902 128 0.013
granulocyte chemotaxis GO:0071621 39 0.013
positive regulation of kinase activity GO:0033674 155 0.013
response to antibiotic GO:0046677 11 0.013
response to radiation GO:0009314 165 0.013
cell substrate adhesion GO:0031589 130 0.013
metal ion homeostasis GO:0055065 189 0.013
protein secretion GO:0009306 111 0.013
mesenchymal cell apoptotic process involved in nephron morphogenesis GO:1901145 4 0.013
chondroitin sulfate proteoglycan metabolic process GO:0050654 20 0.013
negative regulation of transferase activity GO:0051348 85 0.013
negative regulation of secretion GO:0051048 61 0.013
interspecies interaction between organisms GO:0044419 83 0.013
chondroitin sulfate metabolic process GO:0030204 17 0.013
immune response regulating signaling pathway GO:0002764 125 0.013
renal tubule development GO:0061326 87 0.013
stem cell maintenance GO:0019827 130 0.013
response to growth factor GO:0070848 198 0.013
peptidyl tyrosine modification GO:0018212 145 0.013
reactive oxygen species metabolic process GO:0072593 84 0.013
nucleoside phosphate catabolic process GO:1901292 222 0.013
defense response to gram negative bacterium GO:0050829 28 0.013
regulation of interleukin 1 production GO:0032652 26 0.012
regulation of cell growth GO:0001558 91 0.012
cdc42 protein signal transduction GO:0032488 0 0.012
positive regulation of alpha beta t cell activation GO:0046635 39 0.012
regulation of ion transport GO:0043269 215 0.012
t cell proliferation GO:0042098 120 0.012
divalent inorganic cation homeostasis GO:0072507 138 0.012
regulation of defense response to bacterium GO:1900424 3 0.012
proteoglycan metabolic process GO:0006029 38 0.012
regulation of monocyte chemotaxis GO:0090025 3 0.012
interleukin 2 production GO:0032623 33 0.012
chromatin modification GO:0016568 187 0.012
guanosine containing compound metabolic process GO:1901068 144 0.012
ras protein signal transduction GO:0007265 77 0.012
protein localization to organelle GO:0033365 185 0.012
regulation of t cell proliferation GO:0042129 92 0.012
purine nucleoside triphosphate metabolic process GO:0009144 226 0.012
muscle cell development GO:0055001 133 0.012
positive regulation of nucleotide catabolic process GO:0030813 88 0.012
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.012
positive regulation of purine nucleotide catabolic process GO:0033123 88 0.012
ribonucleoside catabolic process GO:0042454 206 0.012
respiratory tube development GO:0030323 167 0.012
metanephros development GO:0001656 79 0.012
kidney epithelium development GO:0072073 121 0.012
regulation of protein modification by small protein conjugation or removal GO:1903320 57 0.012
response to reactive oxygen species GO:0000302 56 0.012
endocytosis GO:0006897 168 0.012
negative regulation of intracellular signal transduction GO:1902532 167 0.012
positive regulation of metalloenzyme activity GO:0048554 3 0.012
binding of sperm to zona pellucida GO:0007339 34 0.012
positive regulation of leukocyte proliferation GO:0070665 73 0.012
response to starvation GO:0042594 65 0.012
regulation of lymphocyte proliferation GO:0050670 117 0.012
feeding behavior GO:0007631 62 0.012
fat cell differentiation GO:0045444 160 0.012
negative regulation of cell cycle GO:0045786 123 0.012
dephosphorylation GO:0016311 129 0.012
myeloid cell differentiation GO:0030099 233 0.012
axon ensheathment GO:0008366 76 0.012
cardiac muscle tissue development GO:0048738 130 0.012
interleukin 8 secretion GO:0072606 3 0.011
multi organism behavior GO:0051705 62 0.011
regulation of circadian rhythm GO:0042752 58 0.011
immunoglobulin production GO:0002377 73 0.011
interferon gamma production GO:0032609 67 0.011
gonad development GO:0008406 141 0.011
Mouse
interleukin 1 production GO:0032612 31 0.011
phenol containing compound metabolic process GO:0018958 60 0.011
response to drug GO:0042493 75 0.011
response to inorganic substance GO:0010035 96 0.011
male gonad development GO:0008584 88 0.011
Mouse
glial cell differentiation GO:0010001 131 0.011
tube formation GO:0035148 140 0.011
anatomical structure maturation GO:0071695 49 0.011
spermatid differentiation GO:0048515 115 0.011
Mouse
digestive system development GO:0055123 200 0.011
negative regulation of cell motility GO:2000146 61 0.011
interleukin 8 production GO:0032637 4 0.011
innate immune response activating signal transduction GO:0002758 50 0.011
cellular magnesium ion homeostasis GO:0010961 3 0.011
paraxial mesodermal cell fate commitment GO:0048343 2 0.011
substrate dependent cell migration cell extension GO:0006930 4 0.011
plasma membrane organization GO:0007009 90 0.011
carbohydrate derivative biosynthetic process GO:1901137 183 0.011
t helper 1 type immune response GO:0042088 25 0.011
stress activated protein kinase signaling cascade GO:0031098 81 0.011
body fluid secretion GO:0007589 53 0.011
maternal process involved in female pregnancy GO:0060135 32 0.011
cell killing GO:0001906 67 0.011
sulfur compound metabolic process GO:0006790 100 0.011
regulation of cell size GO:0008361 72 0.011
regulation of protein stability GO:0031647 52 0.011
sequestering of calcium ion GO:0051208 18 0.011
small gtpase mediated signal transduction GO:0007264 97 0.011
protein oligomerization GO:0051259 67 0.011
epidermis development GO:0008544 187 0.011
positive regulation of transferase activity GO:0051347 167 0.011
protein alkylation GO:0008213 81 0.011
positive regulation of catecholamine secretion GO:0033605 2 0.011
gtp metabolic process GO:0046039 144 0.011
oligopeptide transmembrane transport GO:0035672 4 0.011
negative regulation of kinase activity GO:0033673 81 0.011
cardiocyte differentiation GO:0035051 87 0.011
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 61 0.011
regulation of extent of cell growth GO:0061387 52 0.011
alpha beta t cell activation involved in immune response GO:0002287 31 0.011
protein methylation GO:0006479 81 0.011
regulation of embryonic development GO:0045995 71 0.011
positive regulation of phospholipase c activity GO:0010863 2 0.011
positive regulation of cell motility GO:2000147 116 0.011
Mouse
regulation of cellular response to oxidative stress GO:1900407 19 0.011
ribonucleotide catabolic process GO:0009261 208 0.011
regulation of lipid metabolic process GO:0019216 118 0.011
positive regulation of t cell proliferation GO:0042102 52 0.011
cellular response to acid chemical GO:0071229 68 0.010
cartilage development GO:0051216 140 0.010
regulation of macrophage activation GO:0043030 17 0.010
positive regulation of fibroblast growth factor receptor signaling pathway GO:0045743 3 0.010
ribonucleoside monophosphate metabolic process GO:0009161 80 0.010
myofibril assembly GO:0030239 34 0.010
leukocyte apoptotic process GO:0071887 71 0.010
establishment of protein localization to membrane GO:0090150 54 0.010
positive regulation of hydrolase activity GO:0051345 148 0.010
regulation of neuron apoptotic process GO:0043523 122 0.010
cellular response to lipid GO:0071396 145 0.010

Spink4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of cellular proliferation DOID:14566 0 0.032
cancer DOID:162 0 0.023
organ system cancer DOID:0050686 0 0.022
disease of metabolism DOID:0014667 0 0.018
acquired metabolic disease DOID:0060158 0 0.018
immune system disease DOID:2914 0 0.016
disease of anatomical entity DOID:7 0 0.016
carbohydrate metabolism disease DOID:0050013 0 0.011