Mus musculus

75 known processes

Spinkl

serine protease inhibitor, Kazal type-like

(Aliases: 9530002K18Rik)

Spinkl biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular ketone metabolic process GO:0042180 84 0.058
regulation of cellular ketone metabolic process GO:0010565 66 0.052
cellular amino acid metabolic process GO:0006520 103 0.039
negative regulation of protein metabolic process GO:0051248 282 0.035
Mouse
nucleobase containing small molecule metabolic process GO:0055086 352 0.034
regulation of cellular amine metabolic process GO:0033238 20 0.032
g protein coupled receptor signaling pathway GO:0007186 243 0.032
peptidyl amino acid modification GO:0018193 336 0.031
nucleoside phosphate metabolic process GO:0006753 338 0.029
transmembrane transport GO:0055085 412 0.028
cellular response to lipid GO:0071396 145 0.027
regulation of transforming growth factor beta secretion GO:2001201 1 0.027
purine nucleotide metabolic process GO:0006163 302 0.026
regulation of cellular amino acid metabolic process GO:0006521 5 0.026
response to organonitrogen compound GO:0010243 246 0.026
spermatogenesis GO:0007283 284 0.025
purine containing compound metabolic process GO:0072521 311 0.024
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.023
nucleotide metabolic process GO:0009117 332 0.023
negative regulation of cellular protein metabolic process GO:0032269 247 0.023
Mouse
regulation of secretion by cell GO:1903530 249 0.023
sensory perception GO:0007600 245 0.022
purine ribonucleotide metabolic process GO:0009150 290 0.022
positive regulation of transforming growth factor beta secretion GO:2001203 1 0.022
protein modification by small protein conjugation or removal GO:0070647 207 0.022
positive regulation of cellular amine metabolic process GO:0033240 5 0.022
regulation of mapk cascade GO:0043408 248 0.022
cell division GO:0051301 120 0.022
regulation of secretion GO:0051046 274 0.022
negative regulation of cellular amine metabolic process GO:0033239 1 0.021
cellular amine metabolic process GO:0044106 44 0.021
amine metabolic process GO:0009308 45 0.020
mapk cascade GO:0000165 281 0.020
negative regulation of phosphorylation GO:0042326 166 0.020
protein ubiquitination GO:0016567 171 0.020
sensory organ morphogenesis GO:0090596 242 0.020
protein modification by small protein conjugation GO:0032446 187 0.019
macromolecule catabolic process GO:0009057 281 0.019
ribonucleotide metabolic process GO:0009259 291 0.019
posttranscriptional regulation of gene expression GO:0010608 155 0.019
regulation of cytokine production GO:0001817 266 0.019
regulation of defense response GO:0031347 233 0.019
cellular response to hormone stimulus GO:0032870 150 0.019
organic cyclic compound catabolic process GO:1901361 295 0.018
ribose phosphate metabolic process GO:0019693 291 0.018
regulation of cell cycle GO:0051726 281 0.018
axonogenesis GO:0007409 274 0.018
nitrogen compound transport GO:0071705 271 0.018
regulation of protein localization GO:0032880 231 0.018
negative regulation of molecular function GO:0044092 258 0.018
Mouse
negative regulation of protein modification process GO:0031400 163 0.017
cellular response to cytokine stimulus GO:0071345 189 0.017
positive regulation of nervous system development GO:0051962 221 0.017
male gamete generation GO:0048232 285 0.017
cytokine production GO:0001816 319 0.017
regulation of response to wounding GO:1903034 189 0.017
response to molecule of bacterial origin GO:0002237 143 0.017
cellular homeostasis GO:0019725 240 0.017
oxidation reduction process GO:0055114 342 0.017
regulation of hormone levels GO:0010817 211 0.017
camera type eye development GO:0043010 266 0.016
aromatic compound catabolic process GO:0019439 286 0.016
regulation of organelle organization GO:0033043 289 0.016
regulation of proteolysis GO:0030162 164 0.016
Mouse
cellular nitrogen compound catabolic process GO:0044270 280 0.016
synaptic transmission GO:0007268 329 0.016
ion transmembrane transport GO:0034220 361 0.016
blood vessel morphogenesis GO:0048514 285 0.016
heterocycle catabolic process GO:0046700 280 0.016
organonitrogen compound catabolic process GO:1901565 264 0.016
positive regulation of protein modification process GO:0031401 299 0.016
positive regulation of cell development GO:0010720 237 0.016
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.016
negative regulation of phosphorus metabolic process GO:0010563 184 0.016
apoptotic signaling pathway GO:0097190 306 0.015
carbohydrate metabolic process GO:0005975 230 0.015
regulation of neuron differentiation GO:0045664 281 0.015
olfactory learning GO:0008355 2 0.015
immune effector process GO:0002252 321 0.015
purine ribonucleoside metabolic process GO:0046128 241 0.015
extracellular matrix organization GO:0030198 147 0.015
cation transport GO:0006812 399 0.015
leukocyte differentiation GO:0002521 342 0.015
interleukin 10 secretion GO:0072608 4 0.015
striated muscle tissue development GO:0014706 293 0.014
membrane organization GO:0061024 245 0.014
multicellular organismal homeostasis GO:0048871 164 0.014
negative regulation of phosphate metabolic process GO:0045936 184 0.014
regulation of hydrolase activity GO:0051336 246 0.014
Mouse
cell growth involved in cardiac muscle cell development GO:0061049 3 0.014
microtubule based process GO:0007017 236 0.014
exocytosis GO:0006887 121 0.014
regulation of cell projection organization GO:0031344 206 0.014
response to lipopolysaccharide GO:0032496 128 0.014
amide transport GO:0042886 138 0.014
carbohydrate derivative biosynthetic process GO:1901137 183 0.014
fertilization GO:0009566 127 0.014
Mouse
carbohydrate homeostasis GO:0033500 128 0.014
physiological cardiac muscle hypertrophy GO:0003301 3 0.014
protein catabolic process GO:0030163 221 0.014
protein secretion GO:0009306 111 0.014
regulation of protein transport GO:0051223 163 0.014
glycosyl compound metabolic process GO:1901657 246 0.014
regulation of interleukin 10 secretion GO:2001179 4 0.014
regulation of purine nucleotide metabolic process GO:1900542 169 0.014
purine ribonucleotide catabolic process GO:0009154 208 0.014
purine nucleotide catabolic process GO:0006195 211 0.014
regulation of vesicle mediated transport GO:0060627 139 0.014
regulation of cellular component size GO:0032535 121 0.014
ribonucleoside triphosphate metabolic process GO:0009199 220 0.013
ribonucleotide catabolic process GO:0009261 208 0.013
positive regulation of cell projection organization GO:0031346 95 0.013
nucleoside triphosphate metabolic process GO:0009141 230 0.013
response to organic cyclic compound GO:0014070 198 0.013
peptide transport GO:0015833 133 0.013
lipid biosynthetic process GO:0008610 179 0.013
cellular response to organonitrogen compound GO:0071417 145 0.013
positive regulation of defense response GO:0031349 124 0.013
rho protein signal transduction GO:0007266 32 0.013
hematopoietic progenitor cell differentiation GO:0002244 143 0.013
inflammatory response GO:0006954 244 0.013
negative regulation of nik nf kappab signaling GO:1901223 2 0.013
cellular response to biotic stimulus GO:0071216 92 0.013
nucleotide catabolic process GO:0009166 217 0.013
developmental growth involved in morphogenesis GO:0060560 138 0.013
endomembrane system organization GO:0010256 147 0.013
cellular macromolecule catabolic process GO:0044265 206 0.013
cellular protein complex assembly GO:0043623 116 0.013
nucleoside metabolic process GO:0009116 246 0.013
regulation of establishment of protein localization GO:0070201 181 0.013
purine containing compound catabolic process GO:0072523 213 0.013
negative regulation of cell growth involved in cardiac muscle cell development GO:0061052 2 0.013
negative regulation of insulin secretion involved in cellular response to glucose stimulus GO:0061179 4 0.012
carbohydrate derivative catabolic process GO:1901136 231 0.012
physiological muscle hypertrophy GO:0003298 3 0.012
negative regulation of cell cycle GO:0045786 123 0.012
glucose homeostasis GO:0042593 128 0.012
angiogenesis GO:0001525 201 0.012
homeostasis of number of cells GO:0048872 210 0.012
regulation of cellular catabolic process GO:0031329 242 0.012
organonitrogen compound biosynthetic process GO:1901566 192 0.012
response to peptide hormone GO:0043434 127 0.012
organophosphate catabolic process GO:0046434 232 0.012
cofactor metabolic process GO:0051186 80 0.012
reactive nitrogen species metabolic process GO:2001057 0 0.012
purine nucleoside metabolic process GO:0042278 241 0.012
cellular response to molecule of bacterial origin GO:0071219 83 0.012
leukocyte mediated immunity GO:0002443 174 0.012
transforming growth factor beta secretion GO:0038044 1 0.012
regulation of homeostatic process GO:0032844 182 0.012
ras protein signal transduction GO:0007265 77 0.012
chromatin organization GO:0006325 206 0.012
anatomical structure homeostasis GO:0060249 145 0.012
response to testosterone GO:0033574 3 0.012
cardiocyte differentiation GO:0035051 87 0.012
purine nucleoside triphosphate catabolic process GO:0009146 203 0.012
nucleoside phosphate catabolic process GO:1901292 222 0.012
response to peptide GO:1901652 136 0.012
nuclear division GO:0000280 158 0.012
cell adhesion GO:0007155 329 0.012
cellular chemical homeostasis GO:0055082 215 0.012
insulin secretion GO:0030073 89 0.011
regulation of presynaptic membrane organization GO:1901629 3 0.011
fatty acid metabolic process GO:0006631 121 0.011
regulation of protein kinase activity GO:0045859 232 0.011
endocytosis GO:0006897 168 0.011
cell substrate adhesion GO:0031589 130 0.011
positive regulation of cytokine production GO:0001819 174 0.011
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.011
inorganic ion transmembrane transport GO:0098660 234 0.011
cardiac muscle tissue development GO:0048738 130 0.011
cellular alcohol biosynthetic process GO:0044108 3 0.011
divalent metal ion transport GO:0070838 172 0.011
regulation of cell growth involved in cardiac muscle cell development GO:0061050 3 0.011
methylation GO:0032259 134 0.011
cell growth GO:0016049 130 0.011
regulation of cellular component biogenesis GO:0044087 181 0.011
multicellular organism growth GO:0035264 161 0.011
small gtpase mediated signal transduction GO:0007264 97 0.011
response to acid chemical GO:0001101 111 0.011
regulation of protein maturation GO:1903317 96 0.011
Mouse
regulation of nucleotide metabolic process GO:0006140 169 0.011
maintenance of location GO:0051235 89 0.011
regulation of mitotic cell cycle GO:0007346 126 0.011
inorganic cation transmembrane transport GO:0098662 207 0.011
anion transport GO:0006820 177 0.011
lymphocyte differentiation GO:0030098 242 0.011
cellular lipid metabolic process GO:0044255 323 0.011
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.011
cellular protein catabolic process GO:0044257 155 0.011
cytoplasmic transport GO:0016482 234 0.011
epithelial cell development GO:0002064 159 0.011
regulation of protein catabolic process GO:0042176 108 0.011
organelle fission GO:0048285 170 0.011
leukocyte migration GO:0050900 124 0.011
covalent chromatin modification GO:0016569 163 0.011
cellular response to organic cyclic compound GO:0071407 87 0.010
negative regulation of intracellular signal transduction GO:1902532 167 0.010
activation of immune response GO:0002253 138 0.010
cellular response to lipopolysaccharide GO:0071222 77 0.010
cilium morphogenesis GO:0060271 102 0.010
organic hydroxy compound metabolic process GO:1901615 203 0.010
nucleoside catabolic process GO:0009164 206 0.010
mesodermal cell migration GO:0008078 4 0.010
organophosphate biosynthetic process GO:0090407 122 0.010
monocarboxylic acid metabolic process GO:0032787 191 0.010
dna metabolic process GO:0006259 303 0.010
negative regulation of protein processing GO:0010955 79 0.010
Mouse
lipid localization GO:0010876 126 0.010
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.010
microtubule cytoskeleton organization GO:0000226 157 0.010
regulation of kinase activity GO:0043549 249 0.010
purine ribonucleoside catabolic process GO:0046130 205 0.010
t cell activation GO:0042110 289 0.010
regulation of system process GO:0044057 200 0.010
detection of chemical stimulus involved in sensory perception of smell GO:0050911 4 0.010
chemotaxis GO:0006935 247 0.010
negative regulation of cellular component organization GO:0051129 194 0.010
detection of chemical stimulus involved in sensory perception of taste GO:0050912 3 0.010
peptidyl proline hydroxylation GO:0019511 3 0.010
regulation of cell substrate adhesion GO:0010810 73 0.010
negative regulation of immune system process GO:0002683 209 0.010
purine nucleoside catabolic process GO:0006152 205 0.010
cellular response to acid chemical GO:0071229 68 0.010
regulation of apoptotic signaling pathway GO:2001233 197 0.010
regulation of protein secretion GO:0050708 82 0.010

Spinkl disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.015
musculoskeletal system disease DOID:17 0 0.015
nervous system disease DOID:863 0 0.015
disease of metabolism DOID:0014667 0 0.012
cardiovascular system disease DOID:1287 0 0.011
myopathy DOID:423 0 0.011
muscular disease DOID:0080000 0 0.011
muscle tissue disease DOID:66 0 0.011