Mus musculus

0 known processes

Pak4

p21 protein (Cdc42/Rac)-activated kinase 4

(Aliases: mKIAA1142,5730488L07Rik,AW555722)

Pak4 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
ras protein signal transduction GO:0007265 77 0.135
male gamete generation GO:0048232 285 0.133
small gtpase mediated signal transduction GO:0007264 97 0.102
microtubule based process GO:0007017 236 0.092
cellular component assembly involved in morphogenesis GO:0010927 139 0.089
positive regulation of protein modification process GO:0031401 299 0.088
muscle tissue development GO:0060537 308 0.081
nucleoside phosphate catabolic process GO:1901292 222 0.076
nucleobase containing small molecule metabolic process GO:0055086 352 0.076
spermatogenesis GO:0007283 284 0.071
negative regulation of cellular protein metabolic process GO:0032269 247 0.070
germ cell development GO:0007281 185 0.070
dna metabolic process GO:0006259 303 0.070
positive regulation of programmed cell death GO:0043068 218 0.069
regulation of secretion GO:0051046 274 0.069
microtubule cytoskeleton organization GO:0000226 157 0.069
protein catabolic process GO:0030163 221 0.061
regulation of cell cycle GO:0051726 281 0.060
response to organonitrogen compound GO:0010243 246 0.060
striated muscle tissue development GO:0014706 293 0.060
glycosyl compound catabolic process GO:1901658 206 0.058
oocyte axis specification GO:0007309 2 0.057
respiratory system development GO:0060541 190 0.057
macromolecule catabolic process GO:0009057 281 0.055
protein modification by small protein conjugation or removal GO:0070647 207 0.054
gtp metabolic process GO:0046039 144 0.054
cellular response to dna damage stimulus GO:0006974 207 0.053
regulation of hydrolase activity GO:0051336 246 0.052
organic cyclic compound catabolic process GO:1901361 295 0.052
ribose phosphate metabolic process GO:0019693 291 0.052
neural precursor cell proliferation GO:0061351 121 0.051
negative regulation of protein metabolic process GO:0051248 282 0.050
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.050
purine nucleoside triphosphate metabolic process GO:0009144 226 0.048
purine ribonucleotide catabolic process GO:0009154 208 0.048
purine nucleotide metabolic process GO:0006163 302 0.048
aromatic compound catabolic process GO:0019439 286 0.047
positive regulation of cell activation GO:0050867 158 0.046
oxidation reduction process GO:0055114 342 0.046
purine nucleoside triphosphate catabolic process GO:0009146 203 0.045
oocyte construction GO:0007308 2 0.044
cellular nitrogen compound catabolic process GO:0044270 280 0.043
purine containing compound metabolic process GO:0072521 311 0.043
hexose catabolic process GO:0019320 3 0.043
rho protein signal transduction GO:0007266 32 0.043
nucleoside catabolic process GO:0009164 206 0.043
camera type eye development GO:0043010 266 0.042
cell junction maintenance GO:0034331 4 0.041
ribonucleoside metabolic process GO:0009119 245 0.041
purine ribonucleotide metabolic process GO:0009150 290 0.041
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.039
tube formation GO:0035148 140 0.039
leukocyte differentiation GO:0002521 342 0.038
protein ubiquitination GO:0016567 171 0.037
blastocyst development GO:0001824 80 0.037
peptide transport GO:0015833 133 0.037
stem cell differentiation GO:0048863 268 0.037
regulation of cell activation GO:0050865 289 0.037
ribonucleoside triphosphate metabolic process GO:0009199 220 0.036
purine nucleoside metabolic process GO:0042278 241 0.036
cellular ketone metabolic process GO:0042180 84 0.036
amide transport GO:0042886 138 0.036
negative regulation of cell proliferation GO:0008285 296 0.036
nucleoside phosphate metabolic process GO:0006753 338 0.035
ribonucleotide catabolic process GO:0009261 208 0.035
digestive tract development GO:0048565 190 0.035
positive regulation of hydrolase activity GO:0051345 148 0.035
nucleotide metabolic process GO:0009117 332 0.035
cell adhesion GO:0007155 329 0.035
Fly
organelle assembly GO:0070925 177 0.035
epithelial cell development GO:0002064 159 0.035
positive regulation of cell death GO:0010942 224 0.034
regulation of lymphocyte activation GO:0051249 240 0.034
morphogenesis of embryonic epithelium GO:0016331 159 0.034
regulation of cellular catabolic process GO:0031329 242 0.034
sensory perception GO:0007600 245 0.033
purine ribonucleoside metabolic process GO:0046128 241 0.033
nucleoside triphosphate metabolic process GO:0009141 230 0.033
developmental maturation GO:0021700 193 0.033
purine nucleoside catabolic process GO:0006152 205 0.033
regulation of secretion by cell GO:1903530 249 0.033
gtp catabolic process GO:0006184 143 0.033
epithelial tube morphogenesis GO:0060562 303 0.033
cellular homeostasis GO:0019725 240 0.032
cytoplasmic transport GO:0016482 234 0.032
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.032
membrane organization GO:0061024 245 0.032
morphogenesis of a branching structure GO:0001763 203 0.031
stem cell development GO:0048864 219 0.031
ribonucleoside triphosphate catabolic process GO:0009203 199 0.031
lung development GO:0030324 164 0.031
ribonucleotide metabolic process GO:0009259 291 0.031
b cell activation GO:0042113 161 0.031
purine ribonucleoside catabolic process GO:0046130 205 0.030
positive regulation of protein phosphorylation GO:0001934 242 0.030
cell recognition GO:0008037 83 0.029
cell fate commitment GO:0045165 210 0.029
Fly
t cell activation GO:0042110 289 0.029
regulation of cellular ketone metabolic process GO:0010565 66 0.029
purine nucleotide catabolic process GO:0006195 211 0.029
ribonucleoside catabolic process GO:0042454 206 0.029
lymphocyte differentiation GO:0030098 242 0.028
regulation of hormone levels GO:0010817 211 0.028
intracellular protein transport GO:0006886 204 0.028
ovarian follicle development GO:0001541 40 0.028
homeostasis of number of cells GO:0048872 210 0.028
regulation of neuron differentiation GO:0045664 281 0.028
Fly
transmembrane transport GO:0055085 412 0.028
regulation of kinase activity GO:0043549 249 0.028
apoptotic signaling pathway GO:0097190 306 0.028
Mouse
axonogenesis GO:0007409 274 0.028
organonitrogen compound catabolic process GO:1901565 264 0.027
modification dependent protein catabolic process GO:0019941 133 0.027
neural tube development GO:0021915 160 0.027
rhythmic process GO:0048511 174 0.027
endocytosis GO:0006897 168 0.027
negative regulation of molecular function GO:0044092 258 0.027
nucleoside metabolic process GO:0009116 246 0.027
forebrain development GO:0030900 302 0.027
protein modification by small protein conjugation GO:0032446 187 0.027
regulation of nucleotide catabolic process GO:0030811 122 0.027
cellular response to organonitrogen compound GO:0071417 145 0.027
carbohydrate homeostasis GO:0033500 128 0.027
carbohydrate derivative catabolic process GO:1901136 231 0.027
oogenesis GO:0048477 56 0.027
regulation of proteolysis GO:0030162 164 0.027
regulation of t cell activation GO:0050863 170 0.026
heterocycle catabolic process GO:0046700 280 0.026
immune effector process GO:0002252 321 0.026
posttranscriptional regulation of gene expression GO:0010608 155 0.026
cell maturation GO:0048469 127 0.026
purine containing compound catabolic process GO:0072523 213 0.025
multicellular organismal homeostasis GO:0048871 164 0.025
negative regulation of sterol transport GO:0032372 4 0.025
regulation of homeostatic process GO:0032844 182 0.025
establishment or maintenance of cell polarity GO:0007163 86 0.025
mapk cascade GO:0000165 281 0.025
ear development GO:0043583 200 0.025
glucose homeostasis GO:0042593 128 0.024
positive regulation of cell development GO:0010720 237 0.024
Fly
nucleoside triphosphate catabolic process GO:0009143 205 0.024
response to peptide hormone GO:0043434 127 0.024
female gamete generation GO:0007292 74 0.024
guanosine containing compound catabolic process GO:1901069 144 0.024
regulation of protein localization GO:0032880 231 0.024
regulation of cell cycle process GO:0010564 160 0.024
positive regulation of apoptotic process GO:0043065 217 0.024
skeletal system development GO:0001501 356 0.024
blood vessel morphogenesis GO:0048514 285 0.024
positive regulation of ras gtpase activity GO:0032320 65 0.023
wnt signaling pathway GO:0016055 188 0.023
positive regulation of nervous system development GO:0051962 221 0.023
Fly
cellular response to inorganic substance GO:0071241 37 0.023
hematopoietic progenitor cell differentiation GO:0002244 143 0.023
cytokine production GO:0001816 319 0.023
maintenance of location GO:0051235 89 0.023
lymphocyte proliferation GO:0046651 164 0.023
nucleocytoplasmic transport GO:0006913 139 0.023
cellular lipid metabolic process GO:0044255 323 0.022
negative regulation of immune system process GO:0002683 209 0.022
regulation of protein kinase activity GO:0045859 232 0.022
single organism cell adhesion GO:0098602 156 0.022
Fly
t cell differentiation GO:0030217 174 0.022
reactive oxygen species metabolic process GO:0072593 84 0.022
negative regulation of protein modification process GO:0031400 163 0.022
positive regulation of cellular catabolic process GO:0031331 148 0.022
maternal determination of anterior posterior axis embryo GO:0008358 2 0.022
muscle cell differentiation GO:0042692 261 0.022
regulation of leukocyte mediated immunity GO:0002703 104 0.022
respiratory tube development GO:0030323 167 0.022
peptide hormone secretion GO:0030072 109 0.022
establishment or maintenance of cytoskeleton polarity GO:0030952 2 0.022
stem cell proliferation GO:0072089 117 0.022
oocyte development GO:0048599 33 0.022
regulation of cytokine production GO:0001817 266 0.022
signal transduction by p53 class mediator GO:0072331 51 0.022
placenta development GO:0001890 140 0.022
response to insulin GO:0032868 100 0.021
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.021
epithelial cell proliferation GO:0050673 174 0.021
cell type specific apoptotic process GO:0097285 268 0.021
negative regulation of cholesterol transport GO:0032375 4 0.021
gonad development GO:0008406 141 0.021
cellular response to hormone stimulus GO:0032870 150 0.021
nuclear transport GO:0051169 139 0.021
intracellular mrna localization GO:0008298 4 0.021
regulation of cellular response to stress GO:0080135 159 0.021
intrinsic apoptotic signaling pathway GO:0097193 132 0.021
retinal blood vessel morphogenesis GO:0061304 3 0.021
macromolecule methylation GO:0043414 120 0.021
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.021
chromatin organization GO:0006325 206 0.020
actin cytoskeleton organization GO:0030036 220 0.020
protein targeting GO:0006605 143 0.020
developmental growth involved in morphogenesis GO:0060560 138 0.020
dna repair GO:0006281 107 0.020
positive regulation of nucleotide catabolic process GO:0030813 88 0.020
regulation of apoptotic signaling pathway GO:2001233 197 0.020
Mouse
protein processing GO:0016485 163 0.020
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.020
embryonic organ morphogenesis GO:0048562 276 0.020
response to oxidative stress GO:0006979 123 0.020
regulation of reactive oxygen species metabolic process GO:2000377 40 0.020
neural tube formation GO:0001841 108 0.020
ameboidal type cell migration GO:0001667 128 0.020
negative regulation of protein processing GO:0010955 79 0.020
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.020
oocyte differentiation GO:0009994 35 0.020
defense response to other organism GO:0098542 197 0.019
alpha beta t cell activation GO:0046631 91 0.019
epithelial tube formation GO:0072175 130 0.019
myeloid cell differentiation GO:0030099 233 0.019
response to inorganic substance GO:0010035 96 0.019
regulation of ras protein signal transduction GO:0046578 114 0.019
oocyte anterior posterior axis specification GO:0007314 2 0.019
gene silencing GO:0016458 38 0.019
digestive tract morphogenesis GO:0048546 147 0.019
modification dependent macromolecule catabolic process GO:0043632 133 0.019
cellular chemical homeostasis GO:0055082 215 0.019
neuroblast differentiation GO:0014016 2 0.019
chemotaxis GO:0006935 247 0.019
protein maturation GO:0051604 176 0.019
organophosphate catabolic process GO:0046434 232 0.019
regulation of response to wounding GO:1903034 189 0.019
nitrogen compound transport GO:0071705 271 0.019
regulation of protein serine threonine kinase activity GO:0071900 157 0.019
embryonic epithelial tube formation GO:0001838 130 0.018
satellite cell activation involved in skeletal muscle regeneration GO:0014901 3 0.018
translation GO:0006412 93 0.018
mesoderm development GO:0007498 100 0.018
guanosine containing compound metabolic process GO:1901068 144 0.018
regulation of mapk cascade GO:0043408 248 0.018
regulation of protein catabolic process GO:0042176 108 0.018
multicellular organism growth GO:0035264 161 0.018
positive regulation of nucleotide metabolic process GO:0045981 114 0.018
peptide secretion GO:0002790 114 0.018
urogenital system development GO:0001655 261 0.018
positive regulation of transferase activity GO:0051347 167 0.018
regulation of purine nucleotide metabolic process GO:1900542 169 0.018
regulation of protein processing GO:0070613 96 0.018
dna recombination GO:0006310 92 0.018
neural tube closure GO:0001843 90 0.018
regulation of cell migration GO:0030334 219 0.018
response to acid chemical GO:0001101 111 0.018
wound healing GO:0042060 157 0.018
regulation of protein modification by small protein conjugation or removal GO:1903320 57 0.018
development of primary sexual characteristics GO:0045137 143 0.018
regulation of neural precursor cell proliferation GO:2000177 70 0.018
regulation of stem cell differentiation GO:2000736 50 0.018
transmission of nerve impulse GO:0019226 76 0.018
cellular response to lipid GO:0071396 145 0.018
establishment or maintenance of microtubule cytoskeleton polarity GO:0030951 1 0.018
regulation of membrane potential GO:0042391 192 0.017
retrograde transport endosome to golgi GO:0042147 2 0.017
canonical wnt signaling pathway GO:0060070 130 0.017
meiotic cell cycle GO:0051321 122 0.017
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.017
positive regulation of mapk cascade GO:0043410 170 0.017
stem cell maintenance GO:0019827 130 0.017
regulation of cellular amino acid metabolic process GO:0006521 5 0.017
exocytosis GO:0006887 121 0.017
regulation of organelle organization GO:0033043 289 0.017
leukocyte activation involved in immune response GO:0002366 126 0.017
regulation of cell adhesion GO:0030155 154 0.017
Fly
regulation of stem cell proliferation GO:0072091 78 0.017
gland development GO:0048732 330 0.017
adherens junction maintenance GO:0034334 1 0.017
regulation of protein maturation GO:1903317 96 0.017
hexose metabolic process GO:0019318 98 0.017
negative regulation of proteolysis GO:0045861 74 0.017
morphogenesis of a branching epithelium GO:0061138 193 0.017
response to uv GO:0009411 44 0.017
regulation of purine nucleotide catabolic process GO:0033121 122 0.017
ear morphogenesis GO:0042471 118 0.017
leukocyte mediated immunity GO:0002443 174 0.017
regulation of canonical wnt signaling pathway GO:0060828 82 0.017
cilium morphogenesis GO:0060271 102 0.017
myeloid cell homeostasis GO:0002262 114 0.017
digestive system development GO:0055123 200 0.017
sensory organ morphogenesis GO:0090596 242 0.016
Fly
regulation of translation GO:0006417 71 0.016
connective tissue development GO:0061448 179 0.016
response to starvation GO:0042594 65 0.016
regulation of binding GO:0051098 111 0.016
carbohydrate metabolic process GO:0005975 230 0.016
inner ear morphogenesis GO:0042472 101 0.016
establishment of protein localization to vacuole GO:0072666 4 0.016
body morphogenesis GO:0010171 45 0.016
cation transport GO:0006812 399 0.016
fertilization GO:0009566 127 0.016
positive regulation of gene silencing by mirna GO:2000637 1 0.016
angiogenesis GO:0001525 201 0.016
columnar cuboidal epithelial cell differentiation GO:0002065 82 0.016
establishment of planar polarity GO:0001736 28 0.016
regulation of establishment of protein localization GO:0070201 181 0.016
single organismal cell cell adhesion GO:0016337 131 0.016
Fly
leukocyte proliferation GO:0070661 172 0.016
regulation of satellite cell activation involved in skeletal muscle regeneration GO:0014717 3 0.016
regulation of intracellular transport GO:0032386 159 0.016
cellular macromolecule catabolic process GO:0044265 206 0.016
male gonad development GO:0008584 88 0.016
positive regulation of binding GO:0051099 49 0.016
skeletal system morphogenesis GO:0048705 203 0.016
appendage morphogenesis GO:0035107 149 0.016
regulation of nucleoside metabolic process GO:0009118 130 0.016
nuclear division GO:0000280 158 0.015
positive regulation of protein modification by small protein conjugation or removal GO:1903322 30 0.015
negative regulation of cell size GO:0045792 3 0.015
Fly
cartilage development GO:0051216 140 0.015
negative regulation of planar cell polarity pathway involved in cardiac right atrium morphogenesis GO:2000162 1 0.015
response to molecule of bacterial origin GO:0002237 143 0.015
immunoglobulin production GO:0002377 73 0.015
skin development GO:0043588 220 0.015
protein localization to membrane GO:0072657 108 0.015
regulation of lymphocyte differentiation GO:0045619 107 0.015
lipid biosynthetic process GO:0008610 179 0.015
endomembrane system organization GO:0010256 147 0.015
Fly
somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 51 0.015
regulation of feeding behavior GO:0060259 3 0.015
cell junction assembly GO:0034329 52 0.015
establishment of protein localization to organelle GO:0072594 118 0.015
regulation of epithelial cell proliferation GO:0050678 141 0.015
mitotic cell cycle GO:0000278 195 0.015
regulation of gtp catabolic process GO:0033124 113 0.015
regulation of renal sodium excretion GO:0035813 3 0.015
negative regulation of cholesterol efflux GO:0090370 4 0.015
protein autoprocessing GO:0016540 2 0.015
positive regulation of ran gtpase activity GO:0032853 3 0.015
intestinal epithelial structure maintenance GO:0060729 4 0.015
sensory perception of sound GO:0007605 97 0.014
spermatid development GO:0007286 108 0.014
central nervous system neuron differentiation GO:0021953 162 0.014
retina development in camera type eye GO:0060041 119 0.014
primary neural tube formation GO:0014020 95 0.014
regulation of alpha beta t cell activation GO:0046634 53 0.014
amine metabolic process GO:0009308 45 0.014
adaptive immune response GO:0002250 155 0.014
cellular amino acid metabolic process GO:0006520 103 0.014
cellular response to amino acid stimulus GO:0071230 29 0.014
positive regulation of fibroblast growth factor receptor signaling pathway GO:0045743 3 0.014
myeloid leukocyte differentiation GO:0002573 119 0.014
lateral inhibition GO:0046331 1 0.014
Fly
nucleotide catabolic process GO:0009166 217 0.014
protein localization to vacuole GO:0072665 4 0.014
regulation of cell motility GO:2000145 236 0.014
histone lysine methylation GO:0034968 50 0.014
negative regulation of intracellular signal transduction GO:1902532 167 0.014
cellular response to peptide hormone stimulus GO:0071375 92 0.014
response to lipopolysaccharide GO:0032496 128 0.014
regulation of cellular component biogenesis GO:0044087 181 0.014
extracellular structure organization GO:0043062 148 0.014
mesodermal cell migration GO:0008078 4 0.014
glycosyl compound metabolic process GO:1901657 246 0.014
mitotic cell cycle process GO:1903047 159 0.014
methylation GO:0032259 134 0.014
gliogenesis GO:0042063 141 0.014
positive regulation of lymphocyte activation GO:0051251 140 0.014
interleukin 8 production GO:0032637 4 0.014
regulation of neuron projection development GO:0010975 169 0.014
skeletal muscle organ development GO:0060538 163 0.013
regulation of stress activated mapk cascade GO:0032872 69 0.013
tube closure GO:0060606 91 0.013
regulation of protein transport GO:0051223 163 0.013
response to peptide GO:1901652 136 0.013
regulation of vesicle mediated transport GO:0060627 139 0.013
regulation of peptide transport GO:0090087 91 0.013
regulation of peptidase activity GO:0052547 96 0.013
localization within membrane GO:0051668 4 0.013
cell division GO:0051301 120 0.013
tissue homeostasis GO:0001894 115 0.013
regulation of multi organism process GO:0043900 111 0.013
insulin secretion GO:0030073 89 0.013
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.013
cellular response to lipopolysaccharide GO:0071222 77 0.013
branching morphogenesis of an epithelial tube GO:0048754 159 0.013
cell cell junction organization GO:0045216 72 0.013
genitalia development GO:0048806 37 0.013
peptidyl amino acid modification GO:0018193 336 0.013
Fly
cellular response to carbohydrate stimulus GO:0071322 50 0.013
b cell differentiation GO:0030183 78 0.013
sensory perception of mechanical stimulus GO:0050954 107 0.013
limb development GO:0060173 166 0.013
telencephalon development GO:0021537 186 0.013
glycoprotein metabolic process GO:0009100 116 0.013
fat cell differentiation GO:0045444 160 0.013
regulation of peptide secretion GO:0002791 77 0.013
regulation of body fluid levels GO:0050878 162 0.013
inner cell mass cell proliferation GO:0001833 15 0.013
morphogenesis of a polarized epithelium GO:0001738 37 0.013
synapse assembly GO:0007416 56 0.013
glycerolipid metabolic process GO:0046486 122 0.013
negative regulation of protein maturation GO:1903318 79 0.013
cellular response to peptide GO:1901653 92 0.013
positive regulation of immune effector process GO:0002699 107 0.013
carbohydrate derivative biosynthetic process GO:1901137 183 0.013
positive regulation of growth GO:0045927 104 0.013
hepaticobiliary system development GO:0061008 67 0.013
response to radiation GO:0009314 165 0.013
ossification GO:0001503 216 0.012
mrna metabolic process GO:0016071 84 0.012
dna conformation change GO:0071103 37 0.012
nuclear import GO:0051170 95 0.012
meiotic cell cycle process GO:1903046 77 0.012
gastrulation GO:0007369 116 0.012
multi multicellular organism process GO:0044706 109 0.012
regulation of ras gtpase activity GO:0032318 88 0.012
cell growth GO:0016049 130 0.012
cilium assembly GO:0042384 81 0.012
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.012
divalent inorganic cation transport GO:0072511 178 0.012
negative regulation of phosphorus metabolic process GO:0010563 184 0.012
regulation of lymphocyte proliferation GO:0050670 117 0.012
segmentation GO:0035282 93 0.012
fatty acid metabolic process GO:0006631 121 0.012
regulation of cysteine type endopeptidase activity GO:2000116 65 0.012
spermatid differentiation GO:0048515 115 0.012
cell fate determination involved in pattern specification GO:0060582 1 0.012
positive regulation of purine nucleotide catabolic process GO:0033123 88 0.012
negative regulation of wnt signaling pathway GO:0030178 73 0.012
positive regulation of gtpase activity GO:0043547 85 0.012
limb morphogenesis GO:0035108 149 0.012
protein targeting to vacuole GO:0006623 3 0.012
organelle fission GO:0048285 170 0.012
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.012
double strand break repair GO:0006302 48 0.012
regulation of leukocyte differentiation GO:1902105 159 0.012
mammary gland epithelium development GO:0061180 65 0.012
protein localization to organelle GO:0033365 185 0.012
formation of organ boundary GO:0010160 1 0.012
regulation of protein ubiquitination GO:0031396 52 0.012
regulation of cytoplasmic transport GO:1903649 112 0.012
cell cell junction maintenance GO:0045217 3 0.012
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.012
cellular response to glucose stimulus GO:0071333 45 0.012
cellular response to insulin stimulus GO:0032869 78 0.012
defecation GO:0030421 1 0.012
hindbrain development GO:0030902 128 0.012
apical constriction GO:0003383 4 0.012
production of molecular mediator of immune response GO:0002440 103 0.012
negative regulation of nervous system development GO:0051961 156 0.012
neuron death GO:0070997 154 0.012
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.012
stress activated mapk cascade GO:0051403 80 0.012
regulation of organ morphogenesis GO:2000027 144 0.012
Fly
phospholipid metabolic process GO:0006644 87 0.012
protein methylation GO:0006479 81 0.012
regulation of ossification GO:0030278 112 0.012
lipid localization GO:0010876 126 0.012
molting cycle GO:0042303 90 0.012
cellularization GO:0007349 1 0.012
detection of molecule of bacterial origin GO:0032490 2 0.012
cation homeostasis GO:0055080 212 0.012
meiotic nuclear division GO:0007126 115 0.012
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 68 0.011
covalent chromatin modification GO:0016569 163 0.011
response to light stimulus GO:0009416 135 0.011
anatomical structure homeostasis GO:0060249 145 0.011
response to extracellular stimulus GO:0009991 127 0.011
hormone secretion GO:0046879 128 0.011
regulation of leukocyte proliferation GO:0070663 121 0.011
cardiac muscle cell differentiation GO:0055007 69 0.011
negative regulation of phosphorylation GO:0042326 166 0.011
response to monosaccharide GO:0034284 67 0.011
cellular protein catabolic process GO:0044257 155 0.011
embryonic skeletal system development GO:0048706 120 0.011
neuron apoptotic process GO:0051402 142 0.011
male sex differentiation GO:0046661 109 0.011
cellular response to hexose stimulus GO:0071331 47 0.011
heart morphogenesis GO:0003007 178 0.011
regulation of endopeptidase activity GO:0052548 89 0.011
response to reactive oxygen species GO:0000302 56 0.011
regulation of actin filament based process GO:0032970 99 0.011
protein localization to nucleus GO:0034504 121 0.011
metal ion homeostasis GO:0055065 189 0.011
endocrine system development GO:0035270 98 0.011
carbon catabolite activation of transcription GO:0045991 4 0.011
pole plasm assembly GO:0007315 2 0.011
mesenchymal cell differentiation GO:0048762 107 0.011
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 87 0.011
positive regulation of protein kinase activity GO:0045860 144 0.011
spinal cord development GO:0021510 81 0.011
positive regulation of cell motility GO:2000147 116 0.011
sensory system development GO:0048880 3 0.011
g protein coupled receptor signaling pathway GO:0007186 243 0.011
histone modification GO:0016570 159 0.011

Pak4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.038
inherited metabolic disorder DOID:655 0 0.038
cancer DOID:162 0 0.037
disease of cellular proliferation DOID:14566 0 0.037
organ system cancer DOID:0050686 0 0.032
disease of anatomical entity DOID:7 0 0.015
nervous system disease DOID:863 0 0.015
thoracic cancer DOID:5093 0 0.015
prostate cancer DOID:10283 0 0.014
male reproductive organ cancer DOID:3856 0 0.014
reproductive organ cancer DOID:193 0 0.014
sensory system disease DOID:0050155 0 0.013
eye and adnexa disease DOID:1492 0 0.011
immune system disease DOID:2914 0 0.011