Mus musculus

64 known processes

H3f3a

H3 histone, family 3A

(Aliases: MGC102150,H3f3b,H3.3A)

H3f3a biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
chromatin assembly GO:0031497 13 0.998
Human
protein dna complex subunit organization GO:0071824 28 0.984
Human
dna packaging GO:0006323 30 0.978
nucleosome assembly GO:0006334 7 0.971
Human
dna conformation change GO:0071103 37 0.951
chromatin modification GO:0016568 187 0.933
chromatin organization GO:0006325 206 0.923
Human
gene silencing GO:0016458 38 0.836
gene silencing by rna GO:0031047 19 0.739
rna interference GO:0016246 2 0.723
chromatin assembly or disassembly GO:0006333 16 0.721
Human
posttranscriptional gene silencing GO:0016441 10 0.673
nucleosome positioning GO:0016584 4 0.669
chromatin remodeling GO:0006338 32 0.633
dna metabolic process GO:0006259 303 0.619
chromatin silencing GO:0006342 15 0.553
negative regulation of gene expression epigenetic GO:0045814 15 0.542
posttranscriptional gene silencing by rna GO:0035194 10 0.512
spermatid development GO:0007286 108 0.503
protein methylation GO:0006479 81 0.402
regulation of glycogen catabolic process GO:0005981 2 0.394
protein localization to chromatin GO:0071168 3 0.380
protein alkylation GO:0008213 81 0.362
heterocycle catabolic process GO:0046700 280 0.349
histone methylation GO:0016571 71 0.323
spermatogenesis GO:0007283 284 0.323
male gamete generation GO:0048232 285 0.320
spermatid differentiation GO:0048515 115 0.236
histone acetylation GO:0016573 41 0.227
covalent chromatin modification GO:0016569 163 0.206
cellular polysaccharide catabolic process GO:0044247 5 0.200
histone exchange GO:0043486 8 0.192
carbohydrate derivative catabolic process GO:1901136 231 0.164
segmentation GO:0035282 93 0.159
organic cyclic compound catabolic process GO:1901361 295 0.155
digestive tract morphogenesis GO:0048546 147 0.152
peptidyl lysine acetylation GO:0018394 45 0.149
segment specification GO:0007379 15 0.142
nucleotide metabolic process GO:0009117 332 0.134
internal protein amino acid acetylation GO:0006475 42 0.130
negative regulation of cellular component organization GO:0051129 194 0.119
response to organic cyclic compound GO:0014070 198 0.112
macromolecule methylation GO:0043414 120 0.112
posttranscriptional regulation of gene expression GO:0010608 155 0.109
internal peptidyl lysine acetylation GO:0018393 42 0.100
regulation of cellular catabolic process GO:0031329 242 0.098
germ cell development GO:0007281 185 0.095
digestive system development GO:0055123 200 0.094
positive regulation of cellular amine metabolic process GO:0033240 5 0.090
wound healing GO:0042060 157 0.090
meiotic cell cycle process GO:1903046 77 0.087
regulation of apoptotic signaling pathway GO:2001233 197 0.081
purine containing compound catabolic process GO:0072523 213 0.081
protein localization to organelle GO:0033365 185 0.080
aromatic compound catabolic process GO:0019439 286 0.079
purine nucleoside triphosphate catabolic process GO:0009146 203 0.076
cellular response to organic cyclic compound GO:0071407 87 0.076
regulation of chromatin modification GO:1903308 57 0.072
modification dependent macromolecule catabolic process GO:0043632 133 0.072
regulation of cellular amine metabolic process GO:0033238 20 0.070
protein ubiquitination GO:0016567 171 0.068
negative regulation of chromosome organization GO:2001251 30 0.067
histone modification GO:0016570 159 0.067
dna templated transcription termination GO:0006353 4 0.063
meiotic cell cycle GO:0051321 122 0.063
regionalization GO:0003002 337 0.062
response to heat GO:0009408 27 0.062
regulation of chromosome organization GO:0033044 83 0.061
germ line stem cell division GO:0042078 2 0.061
gonad development GO:0008406 141 0.059
Worm
regulation of chromatin organization GO:1902275 57 0.058
nucleoside phosphate catabolic process GO:1901292 222 0.058
ossification GO:0001503 216 0.058
digestive tract development GO:0048565 190 0.058
cellular amino acid metabolic process GO:0006520 103 0.057
apoptotic signaling pathway GO:0097190 306 0.057
ribonucleoside triphosphate catabolic process GO:0009203 199 0.056
purine nucleotide catabolic process GO:0006195 211 0.055
dna replication independent nucleosome assembly GO:0006336 1 0.055
Human
histone h3 k9 methylation GO:0051567 17 0.053
dendrite development GO:0016358 115 0.053
dna repair GO:0006281 107 0.052
response to steroid hormone GO:0048545 56 0.052
response to alcohol GO:0097305 48 0.051
cellular response to dna damage stimulus GO:0006974 207 0.051
small gtpase mediated signal transduction GO:0007264 97 0.050
ribonucleotide catabolic process GO:0009261 208 0.049
cellular response to alcohol GO:0097306 23 0.048
organophosphate catabolic process GO:0046434 232 0.048
protein acylation GO:0043543 64 0.048
cellular response to estrogen stimulus GO:0071391 12 0.047
dna methylation involved in gamete generation GO:0043046 15 0.047
purine ribonucleoside catabolic process GO:0046130 205 0.046
nucleoside phosphate metabolic process GO:0006753 338 0.046
regulation of cellular ketone metabolic process GO:0010565 66 0.046
ribonucleoside metabolic process GO:0009119 245 0.045
purine ribonucleoside metabolic process GO:0046128 241 0.045
regulation of mitotic cell cycle GO:0007346 126 0.045
intracellular receptor signaling pathway GO:0030522 74 0.044
regulation of mapk cascade GO:0043408 248 0.044
genitalia development GO:0048806 37 0.044
Worm
development of primary sexual characteristics GO:0045137 143 0.044
Worm
amine metabolic process GO:0009308 45 0.043
purine nucleoside catabolic process GO:0006152 205 0.043
mrna catabolic process GO:0006402 22 0.042
methylation GO:0032259 134 0.041
inflammatory response GO:0006954 244 0.040
ribose phosphate metabolic process GO:0019693 291 0.040
cellular amine metabolic process GO:0044106 44 0.040
negative regulation of organelle organization GO:0010639 90 0.039
regulation of cellular amino acid metabolic process GO:0006521 5 0.039
atp metabolic process GO:0046034 75 0.038
cellular nitrogen compound catabolic process GO:0044270 280 0.037
response to estrogen GO:0043627 24 0.037
embryonic organ morphogenesis GO:0048562 276 0.037
ribonucleotide metabolic process GO:0009259 291 0.036
nucleoside triphosphate catabolic process GO:0009143 205 0.036
lung development GO:0030324 164 0.036
intracellular protein transport GO:0006886 204 0.036
nucleus organization GO:0006997 45 0.035
organelle fission GO:0048285 170 0.035
purine nucleoside metabolic process GO:0042278 241 0.035
histone lysine methylation GO:0034968 50 0.035
positive regulation of glycogen catabolic process GO:0045819 2 0.034
purine ribonucleoside monophosphate catabolic process GO:0009169 57 0.034
oxidation reduction process GO:0055114 342 0.034
dna alkylation GO:0006305 43 0.034
glycosyl compound catabolic process GO:1901658 206 0.034
regulation of transferase activity GO:0051338 263 0.033
ribonucleoside monophosphate metabolic process GO:0009161 80 0.032
mrna metabolic process GO:0016071 84 0.032
purine nucleoside triphosphate metabolic process GO:0009144 226 0.032
microtubule based process GO:0007017 236 0.032
cellular response to hormone stimulus GO:0032870 150 0.032
nucleoside triphosphate metabolic process GO:0009141 230 0.032
positive regulation of protein modification process GO:0031401 299 0.032
glycosyl compound metabolic process GO:1901657 246 0.032
cell growth GO:0016049 130 0.031
Human
nucleoside metabolic process GO:0009116 246 0.031
purine nucleoside monophosphate catabolic process GO:0009128 58 0.031
striated muscle tissue development GO:0014706 293 0.030
ribonucleoside catabolic process GO:0042454 206 0.030
establishment of protein localization to organelle GO:0072594 118 0.030
muscle cell differentiation GO:0042692 261 0.030
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.030
transmembrane transport GO:0055085 412 0.029
nucleoside catabolic process GO:0009164 206 0.029
cation transmembrane transport GO:0098655 266 0.029
carbohydrate metabolic process GO:0005975 230 0.029
response to temperature stimulus GO:0009266 55 0.029
negative regulation of cell proliferation GO:0008285 296 0.029
ribonucleoside monophosphate catabolic process GO:0009158 57 0.029
ribonucleoside triphosphate metabolic process GO:0009199 220 0.029
nucleotide catabolic process GO:0009166 217 0.029
translesion synthesis GO:0019985 1 0.028
respiratory tube development GO:0030323 167 0.028
spermatid nucleus differentiation GO:0007289 19 0.028
regulation of organelle organization GO:0033043 289 0.028
cytokinesis GO:0000910 17 0.027
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.027
negative regulation of intracellular signal transduction GO:1902532 167 0.027
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.027
cellular response to lipid GO:0071396 145 0.027
male sex differentiation GO:0046661 109 0.026
rhythmic process GO:0048511 174 0.026
chromosome segregation GO:0007059 48 0.026
ras protein signal transduction GO:0007265 77 0.026
purine nucleotide metabolic process GO:0006163 302 0.026
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.026
peptidyl lysine modification GO:0018205 77 0.026
inorganic ion transmembrane transport GO:0098660 234 0.026
regulation of extrinsic apoptotic signaling pathway GO:2001236 77 0.026
positive regulation of cell development GO:0010720 237 0.026
mitotic cytokinesis GO:0000281 4 0.026
purine containing compound metabolic process GO:0072521 311 0.025
purine ribonucleotide catabolic process GO:0009154 208 0.025
negative regulation of apoptotic signaling pathway GO:2001234 104 0.025
respiratory system development GO:0060541 190 0.025
response to molecule of bacterial origin GO:0002237 143 0.024
cellular macromolecule catabolic process GO:0044265 206 0.024
cell fate commitment GO:0045165 210 0.024
nuclear transcribed mrna catabolic process GO:0000956 16 0.024
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.024
dna methylation GO:0006306 43 0.024
cellular ketone metabolic process GO:0042180 84 0.024
organonitrogen compound catabolic process GO:1901565 264 0.023
rna catabolic process GO:0006401 29 0.023
peptidyl amino acid modification GO:0018193 336 0.023
protein targeting GO:0006605 143 0.023
centrosome separation GO:0051299 4 0.023
regulation of histone methylation GO:0031060 30 0.023
stem cell differentiation GO:0048863 268 0.023
camera type eye development GO:0043010 266 0.023
cellular polysaccharide metabolic process GO:0044264 38 0.023
multicellular organism growth GO:0035264 161 0.023
sperm individualization GO:0007291 1 0.023
nucleobase containing small molecule metabolic process GO:0055086 352 0.023
cellular response to steroid hormone stimulus GO:0071383 33 0.023
nucleoside monophosphate catabolic process GO:0009125 59 0.022
purine ribonucleotide metabolic process GO:0009150 290 0.022
positive regulation of programmed cell death GO:0043068 218 0.022
protein localization to chromosome GO:0034502 6 0.022
regulation of cellular component biogenesis GO:0044087 181 0.022
generation of precursor metabolites and energy GO:0006091 103 0.022
stem cell development GO:0048864 219 0.022
intrinsic apoptotic signaling pathway by p53 class mediator GO:0072332 35 0.021
cellularization GO:0007349 1 0.021
regulation of kinase activity GO:0043549 249 0.021
protein maturation GO:0051604 176 0.021
developmental growth involved in morphogenesis GO:0060560 138 0.020
positive regulation of apoptotic signaling pathway GO:2001235 95 0.020
cytoplasmic transport GO:0016482 234 0.020
regulation of cellular response to stress GO:0080135 159 0.020
response to lipopolysaccharide GO:0032496 128 0.020
axonogenesis GO:0007409 274 0.020
atp catabolic process GO:0006200 55 0.020
developmental cell growth GO:0048588 84 0.020
regulation of lymphocyte activation GO:0051249 240 0.020
regulation of cell cycle GO:0051726 281 0.020
protein depolymerization GO:0051261 34 0.020
embryonic digestive tract development GO:0048566 27 0.019
response to ionizing radiation GO:0010212 42 0.019
positive regulation of nervous system development GO:0051962 221 0.019
positive regulation of cellular catabolic process GO:0031331 148 0.019
negative regulation of immune system process GO:0002683 209 0.019
nuclear import GO:0051170 95 0.019
regulation of defense response GO:0031347 233 0.019
response to oxidative stress GO:0006979 123 0.019
regulation of nucleotide catabolic process GO:0030811 122 0.019
b cell differentiation GO:0030183 78 0.019
spermatogenesis exchange of chromosomal proteins GO:0035093 4 0.018
macromolecular complex disassembly GO:0032984 43 0.018
positive regulation of neuron projection development GO:0010976 79 0.018
nucleocytoplasmic transport GO:0006913 139 0.018
dna replication GO:0006260 52 0.018
cellular glucan metabolic process GO:0006073 32 0.018
positive regulation of neuron differentiation GO:0045666 141 0.018
microtubule cytoskeleton organization GO:0000226 157 0.018
zymogen activation GO:0031638 41 0.018
circulatory system process GO:0003013 197 0.018
regulation of anatomical structure size GO:0090066 178 0.018
response to acid chemical GO:0001101 111 0.018
glucan catabolic process GO:0009251 5 0.018
macromolecule catabolic process GO:0009057 281 0.018
trunk segmentation GO:0035290 4 0.018
muscle tissue development GO:0060537 308 0.018
male gonad development GO:0008584 88 0.017
mapk cascade GO:0000165 281 0.017
positive regulation of hydrolase activity GO:0051345 148 0.017
regulation of system process GO:0044057 200 0.017
positive regulation of transferase activity GO:0051347 167 0.017
regulation of neuron differentiation GO:0045664 281 0.017
regulation of cell adhesion GO:0030155 154 0.017
endomembrane system organization GO:0010256 147 0.017
positive regulation of organelle organization GO:0010638 128 0.017
intrinsic apoptotic signaling pathway in response to dna damage GO:0008630 57 0.017
positive regulation of cell death GO:0010942 224 0.017
epidermis development GO:0008544 187 0.017
polysaccharide metabolic process GO:0005976 39 0.017
neuron projection extension GO:1990138 64 0.017
positive regulation of protein kinase activity GO:0045860 144 0.017
meiotic chromosome segregation GO:0045132 19 0.016
fertilization GO:0009566 127 0.016
negative regulation of cellular protein metabolic process GO:0032269 247 0.016
regulation of rna splicing GO:0043484 37 0.016
negative regulation of phagocytosis GO:0050765 4 0.016
response to organonitrogen compound GO:0010243 246 0.016
response to sterol GO:0036314 4 0.016
positive regulation of nucleotide catabolic process GO:0030813 88 0.016
purine nucleoside monophosphate metabolic process GO:0009126 81 0.016
cell fate specification GO:0001708 72 0.016
positive regulation of mapk cascade GO:0043410 170 0.015
negative regulation of cell activation GO:0050866 111 0.015
chemotaxis GO:0006935 247 0.015
regulation of cellular protein catabolic process GO:1903362 61 0.015
embryonic digestive tract morphogenesis GO:0048557 17 0.015
atp dependent chromatin remodeling GO:0043044 9 0.015
nucleoside monophosphate metabolic process GO:0009123 85 0.015
positive regulation of apoptotic process GO:0043065 217 0.015
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.015
stem cell maintenance GO:0019827 130 0.015
telencephalon development GO:0021537 186 0.015
regulation of protein kinase activity GO:0045859 232 0.015
positive regulation of cell morphogenesis involved in differentiation GO:0010770 72 0.015
regulation of cell growth GO:0001558 91 0.015
Human
intrinsic apoptotic signaling pathway GO:0097193 132 0.014
membrane organization GO:0061024 245 0.014
response to radiation GO:0009314 165 0.014
regulation of protein catabolic process GO:0042176 108 0.014
positive regulation of cell projection organization GO:0031346 95 0.014
extrinsic apoptotic signaling pathway GO:0097191 126 0.014
inorganic cation transmembrane transport GO:0098662 207 0.014
learning or memory GO:0007611 148 0.014
developmental maturation GO:0021700 193 0.014
innate immune response GO:0045087 157 0.014
negative regulation of b cell differentiation GO:0045578 4 0.013
regulation of neuron projection development GO:0010975 169 0.013
adult behavior GO:0030534 135 0.013
regulation of nucleotide metabolic process GO:0006140 169 0.013
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.013
meiotic nuclear division GO:0007126 115 0.013
glucan metabolic process GO:0044042 32 0.013
regulation of mrna splicing via spliceosome GO:0048024 32 0.013
negative regulation of protein processing GO:0010955 79 0.013
regulation of chromatin silencing GO:0031935 2 0.013
cellular homeostasis GO:0019725 240 0.013
response to inorganic substance GO:0010035 96 0.013
circadian regulation of gene expression GO:0032922 48 0.013
signal transduction by p53 class mediator GO:0072331 51 0.013
negative regulation of cytoskeleton organization GO:0051494 36 0.013
regulation of erk1 and erk2 cascade GO:0070372 71 0.013
negative regulation of phosphorylation GO:0042326 166 0.013
tissue regeneration GO:0042246 22 0.012
protein processing GO:0016485 163 0.012
regulation of neurotransmitter levels GO:0001505 87 0.012
regulation of proteasomal protein catabolic process GO:0061136 46 0.012
cell type specific apoptotic process GO:0097285 268 0.012
gene silencing by mirna GO:0035195 10 0.012
single organism nuclear import GO:1902593 95 0.012
establishment or maintenance of microtubule cytoskeleton polarity GO:0030951 1 0.012
asymmetric stem cell division GO:0098722 3 0.012
organelle assembly GO:0070925 177 0.012
protein localization to nucleus GO:0034504 121 0.012
pharynx development GO:0060465 1 0.012
positive regulation of myeloid cell differentiation GO:0045639 43 0.012
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.012
regulation of establishment of protein localization GO:0070201 181 0.012
positive regulation of chromatin modification GO:1903310 28 0.012
response to estradiol GO:0032355 12 0.012
negative regulation of protein metabolic process GO:0051248 282 0.012
reactive oxygen species metabolic process GO:0072593 84 0.011
positive regulation of defense response GO:0031349 124 0.011
cardiac muscle cell contraction GO:0086003 7 0.011
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.011
cellular protein complex assembly GO:0043623 116 0.011
regulation of mrna processing GO:0050684 41 0.011
regulation of hydrolase activity GO:0051336 246 0.011
regulation of multi organism process GO:0043900 111 0.011
monosaccharide metabolic process GO:0005996 106 0.011
compound eye development GO:0048749 1 0.011
regulation of lymphocyte differentiation GO:0045619 107 0.011
cellular response to organonitrogen compound GO:0071417 145 0.011
cellular response to transforming growth factor beta stimulus GO:0071560 88 0.011
development of primary male sexual characteristics GO:0046546 88 0.011
positive regulation of chromosome organization GO:2001252 33 0.011
peptidyl tyrosine phosphorylation GO:0018108 143 0.011
oogenesis GO:0048477 56 0.011
anatomical structure homeostasis GO:0060249 145 0.011
g protein coupled receptor signaling pathway GO:0007186 243 0.011
mesenchyme development GO:0060485 152 0.011
cognition GO:0050890 149 0.011
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 56 0.011
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.011
regulation of nucleoside metabolic process GO:0009118 130 0.011
positive regulation of nucleotide metabolic process GO:0045981 114 0.011
axon guidance GO:0007411 141 0.011
intracellular mrna localization GO:0008298 4 0.010
hindbrain development GO:0030902 128 0.010
regulation of carbohydrate metabolic process GO:0006109 75 0.010
primary neural tube formation GO:0014020 95 0.010
hexose metabolic process GO:0019318 98 0.010
nitrogen compound transport GO:0071705 271 0.010
protein catabolic process GO:0030163 221 0.010
negative regulation of apoptotic cell clearance GO:2000426 1 0.010
positive regulation of protein phosphorylation GO:0001934 242 0.010
carbohydrate catabolic process GO:0016052 32 0.010
protein import GO:0017038 101 0.010
regulation of response to dna damage stimulus GO:2001020 34 0.010

H3f3a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.033
nervous system disease DOID:863 0 0.033
physical disorder DOID:0080015 0 0.019