Mus musculus

78 known processes

Spic

Spi-C transcription factor (Spi-1/PU.1 related)

(Aliases: AU019198,C76795,Prf,Spi-C)

Spic biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of cell activation GO:0050865 289 0.232
regulation of lymphocyte activation GO:0051249 240 0.222
inflammatory response GO:0006954 244 0.194
regulation of cytokine production GO:0001817 266 0.167
Mouse
immune effector process GO:0002252 321 0.165
regulation of t cell activation GO:0050863 170 0.157
cellular amino acid metabolic process GO:0006520 103 0.150
leukocyte differentiation GO:0002521 342 0.135
positive regulation of t cell activation GO:0050870 101 0.130
cytokine production GO:0001816 319 0.118
Mouse
leukocyte proliferation GO:0070661 172 0.117
Mouse
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.113
regulation of t cell proliferation GO:0042129 92 0.112
regulation of inflammatory response GO:0050727 147 0.107
regulation of protein localization GO:0032880 231 0.107
lymphocyte proliferation GO:0046651 164 0.101
Mouse
cellular ketone metabolic process GO:0042180 84 0.098
regulation of secretion GO:0051046 274 0.096
t cell proliferation GO:0042098 120 0.093
Mouse
response to molecule of bacterial origin GO:0002237 143 0.091
t cell activation GO:0042110 289 0.090
Mouse
defense response to other organism GO:0098542 197 0.090
regulation of leukocyte proliferation GO:0070663 121 0.086
regulation of secretion by cell GO:1903530 249 0.085
innate immune response GO:0045087 157 0.083
mapk cascade GO:0000165 281 0.082
positive regulation of immune effector process GO:0002699 107 0.079
cation transport GO:0006812 399 0.077
regulation of cellular amine metabolic process GO:0033238 20 0.077
regulation of cellular ketone metabolic process GO:0010565 66 0.074
regulation of homeostatic process GO:0032844 182 0.074
leukocyte mediated immunity GO:0002443 174 0.072
regulation of protein secretion GO:0050708 82 0.071
regulation of establishment of protein localization GO:0070201 181 0.070
regulation of lymphocyte proliferation GO:0050670 117 0.070
cell killing GO:0001906 67 0.069
positive regulation of cellular amine metabolic process GO:0033240 5 0.069
regulation of defense response GO:0031347 233 0.066
apoptotic signaling pathway GO:0097190 306 0.066
myeloid cell differentiation GO:0030099 233 0.065
maintenance of location GO:0051235 89 0.064
cellular amine metabolic process GO:0044106 44 0.064
adaptive immune response GO:0002250 155 0.064
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.063
amine metabolic process GO:0009308 45 0.062
sequestering of calcium ion GO:0051208 18 0.061
cellular chemical homeostasis GO:0055082 215 0.060
positive regulation of lymphocyte activation GO:0051251 140 0.059
extrinsic apoptotic signaling pathway GO:0097191 126 0.058
nitrogen compound transport GO:0071705 271 0.057
regulation of cellular amino acid metabolic process GO:0006521 5 0.057
cell adhesion GO:0007155 329 0.057
transmission of nerve impulse GO:0019226 76 0.057
cell type specific apoptotic process GO:0097285 268 0.054
sequestering of metal ion GO:0051238 19 0.054
cytokine biosynthetic process GO:0042089 68 0.053
positive regulation of protein modification process GO:0031401 299 0.053
lymphocyte mediated immunity GO:0002449 139 0.052
cellular homeostasis GO:0019725 240 0.051
endocytosis GO:0006897 168 0.050
urogenital system development GO:0001655 261 0.050
regulation of innate immune response GO:0045088 91 0.050
myeloid leukocyte differentiation GO:0002573 119 0.049
membrane organization GO:0061024 245 0.049
regulation of mapk cascade GO:0043408 248 0.049
cellular response to lipopolysaccharide GO:0071222 77 0.049
positive regulation of cytokine production GO:0001819 174 0.048
cellular response to lipid GO:0071396 145 0.047
positive regulation of lymphocyte proliferation GO:0050671 70 0.047
regulation of multi organism process GO:0043900 111 0.046
positive regulation of inflammatory response GO:0050729 47 0.046
regulation of cytokine biosynthetic process GO:0042035 59 0.046
regulation of apoptotic signaling pathway GO:2001233 197 0.045
exocytosis GO:0006887 121 0.045
regulation of lipid metabolic process GO:0019216 118 0.044
mitotic cell cycle process GO:1903047 159 0.043
cytokine mediated signaling pathway GO:0019221 115 0.043
response to lipopolysaccharide GO:0032496 128 0.042
symbiosis encompassing mutualism through parasitism GO:0044403 83 0.042
regulation of ion transport GO:0043269 215 0.041
positive regulation of cell activation GO:0050867 158 0.041
positive regulation of cytokine biosynthetic process GO:0042108 40 0.041
homeostasis of number of cells GO:0048872 210 0.041
multicellular organismal signaling GO:0035637 91 0.040
leukocyte mediated cytotoxicity GO:0001909 62 0.040
cellular lipid metabolic process GO:0044255 323 0.040
regulation of monocyte chemotaxis GO:0090025 3 0.040
cytoplasmic transport GO:0016482 234 0.040
cytokine secretion GO:0050663 72 0.040
regulation of protein transport GO:0051223 163 0.039
t cell differentiation GO:0030217 174 0.039
response to organonitrogen compound GO:0010243 246 0.039
regulation of intracellular transport GO:0032386 159 0.038
cellular response to biotic stimulus GO:0071216 92 0.038
lymphocyte differentiation GO:0030098 242 0.038
regulation of cell migration GO:0030334 219 0.038
leukocyte activation involved in immune response GO:0002366 126 0.037
cytokine metabolic process GO:0042107 71 0.036
detection of yeast GO:0001879 2 0.036
digestive system development GO:0055123 200 0.036
Mouse
positive regulation of protein phosphorylation GO:0001934 242 0.035
mitotic cell cycle GO:0000278 195 0.035
regulation of kinase activity GO:0043549 249 0.035
negative regulation of homeostatic process GO:0032845 71 0.035
chemotaxis GO:0006935 247 0.035
positive regulation of defense response GO:0031349 124 0.035
negative regulation of cellular protein metabolic process GO:0032269 247 0.035
sensory perception GO:0007600 245 0.034
defense response to bacterium GO:0042742 119 0.034
regulation of protein kinase activity GO:0045859 232 0.034
multicellular organismal homeostasis GO:0048871 164 0.034
small gtpase mediated signal transduction GO:0007264 97 0.033
response to organic cyclic compound GO:0014070 198 0.033
regulation of vesicle mediated transport GO:0060627 139 0.033
myeloid leukocyte migration GO:0097529 57 0.033
regulation of cell killing GO:0031341 40 0.033
kidney development GO:0001822 213 0.033
transmembrane transport GO:0055085 412 0.033
action potential GO:0001508 78 0.033
protein secretion GO:0009306 111 0.032
negative regulation of molecular function GO:0044092 258 0.032
negative regulation of cell activation GO:0050866 111 0.032
interferon gamma production GO:0032609 67 0.031
regulation of leukocyte mediated cytotoxicity GO:0001910 38 0.031
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 87 0.031
ion transmembrane transport GO:0034220 361 0.031
interspecies interaction between organisms GO:0044419 83 0.031
regulation of response to wounding GO:1903034 189 0.031
negative regulation of immune system process GO:0002683 209 0.030
Mouse
defense response to virus GO:0051607 68 0.030
immune response activating cell surface receptor signaling pathway GO:0002429 72 0.030
Mouse
gland development GO:0048732 330 0.029
Mouse
cellular ion homeostasis GO:0006873 165 0.029
reactive oxygen species metabolic process GO:0072593 84 0.029
positive regulation of transferase activity GO:0051347 167 0.029
positive regulation of programmed cell death GO:0043068 218 0.029
organic hydroxy compound metabolic process GO:1901615 203 0.029
single organism cell adhesion GO:0098602 156 0.029
neuronal action potential GO:0019228 54 0.029
posttranscriptional regulation of gene expression GO:0010608 155 0.029
regulation of cell cycle process GO:0010564 160 0.029
positive regulation of cell killing GO:0031343 33 0.029
positive regulation of leukocyte mediated immunity GO:0002705 70 0.029
positive regulation of homeostatic process GO:0032846 64 0.029
natural killer cell activation GO:0030101 44 0.029
Mouse
positive regulation of monocyte chemotaxis GO:0090026 2 0.028
regulation of interferon gamma production GO:0032649 57 0.028
divalent inorganic cation transport GO:0072511 178 0.028
muscle tissue development GO:0060537 308 0.028
regulation of membrane potential GO:0042391 192 0.028
anatomical structure homeostasis GO:0060249 145 0.028
positive regulation of cell death GO:0010942 224 0.028
inorganic ion transmembrane transport GO:0098660 234 0.028
regulation of hormone levels GO:0010817 211 0.028
bone remodeling GO:0046849 53 0.028
macromolecule catabolic process GO:0009057 281 0.027
t cell differentiation in thymus GO:0033077 77 0.027
renal system development GO:0072001 225 0.027
calcium ion transport GO:0006816 159 0.027
cellular response to cytokine stimulus GO:0071345 189 0.027
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.027
positive regulation of leukocyte proliferation GO:0070665 73 0.027
leukocyte chemotaxis GO:0030595 69 0.027
muscle cell differentiation GO:0042692 261 0.027
cellular response to molecule of bacterial origin GO:0071219 83 0.026
positive regulation of innate immune response GO:0045089 80 0.026
anion transport GO:0006820 177 0.026
rho protein signal transduction GO:0007266 32 0.026
regulation of system process GO:0044057 200 0.026
divalent metal ion transport GO:0070838 172 0.026
cation transmembrane transport GO:0098655 266 0.026
male gamete generation GO:0048232 285 0.025
cytosolic calcium ion transport GO:0060401 48 0.025
detection of fungus GO:0016046 2 0.025
negative regulation of growth GO:0045926 99 0.025
nucleobase containing small molecule metabolic process GO:0055086 352 0.025
positive regulation of leukocyte mediated cytotoxicity GO:0001912 31 0.025
organelle localization GO:0051640 179 0.025
glucose homeostasis GO:0042593 128 0.025
amide transport GO:0042886 138 0.025
positive regulation of apoptotic process GO:0043065 217 0.025
regulation of lymphocyte mediated immunity GO:0002706 84 0.025
striated muscle tissue development GO:0014706 293 0.024
peptidyl amino acid modification GO:0018193 336 0.024
cell division GO:0051301 120 0.024
negative regulation of cellular component organization GO:0051129 194 0.024
glycoprotein metabolic process GO:0009100 116 0.024
peptidyl tyrosine phosphorylation GO:0018108 143 0.024
nucleoside phosphate metabolic process GO:0006753 338 0.024
metal ion homeostasis GO:0055065 189 0.024
regulation of map kinase activity GO:0043405 120 0.024
negative regulation of cell proliferation GO:0008285 296 0.024
endomembrane system organization GO:0010256 147 0.024
cation homeostasis GO:0055080 212 0.024
lipid localization GO:0010876 126 0.023
ear development GO:0043583 200 0.023
cognition GO:0050890 149 0.023
regulation of cellular response to stress GO:0080135 159 0.023
helper t cell chemotaxis GO:0035704 1 0.023
aromatic compound catabolic process GO:0019439 286 0.023
positive regulation of protein secretion GO:0050714 52 0.023
regulation of protein serine threonine kinase activity GO:0071900 157 0.023
positive regulation of t cell proliferation GO:0042102 52 0.023
inorganic cation transmembrane transport GO:0098662 207 0.023
learning or memory GO:0007611 148 0.023
skeletal system development GO:0001501 356 0.023
regulation of cell cycle GO:0051726 281 0.023
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.022
negative regulation of synapse assembly GO:0051964 3 0.022
carbohydrate metabolic process GO:0005975 230 0.022
microglia differentiation GO:0014004 2 0.022
negative regulation of macrophage apoptotic process GO:2000110 3 0.022
regulation of leukocyte mediated immunity GO:0002703 104 0.022
cellular response to dna damage stimulus GO:0006974 207 0.022
cell activation involved in immune response GO:0002263 126 0.022
divalent inorganic cation homeostasis GO:0072507 138 0.022
stimulatory c type lectin receptor signaling pathway GO:0002223 2 0.022
carbohydrate derivative biosynthetic process GO:1901137 183 0.022
regulation of cellular component biogenesis GO:0044087 181 0.022
fat cell differentiation GO:0045444 160 0.022
regulation of organelle organization GO:0033043 289 0.022
dna metabolic process GO:0006259 303 0.022
regulation of leukocyte apoptotic process GO:2000106 56 0.022
regulation of transferase activity GO:0051338 263 0.022
organic anion transport GO:0015711 137 0.022
organelle fission GO:0048285 170 0.022
alpha beta t cell proliferation GO:0046633 21 0.022
Mouse
neuron death GO:0070997 154 0.021
positive regulation of t cell receptor signaling pathway GO:0050862 4 0.021
protein processing GO:0016485 163 0.021
regulation of cell adhesion GO:0030155 154 0.021
regulation of interleukin 8 production GO:0032677 3 0.021
ras protein signal transduction GO:0007265 77 0.021
erk1 and erk2 cascade GO:0070371 77 0.021
positive regulation of protein transport GO:0051222 93 0.021
immunoglobulin mediated immune response GO:0016064 69 0.021
signal transduction in absence of ligand GO:0038034 55 0.021
negative regulation of protein phosphorylation GO:0001933 126 0.021
negative regulation of protein metabolic process GO:0051248 282 0.021
regulation of proteolysis GO:0030162 164 0.021
nuclear transport GO:0051169 139 0.021
positive regulation of secretion by cell GO:1903532 114 0.021
positive regulation of mapk cascade GO:0043410 170 0.020
digestive tract development GO:0048565 190 0.020
Mouse
angiogenesis GO:0001525 201 0.020
killing by host of symbiont cells GO:0051873 11 0.020
cellular nitrogen compound catabolic process GO:0044270 280 0.020
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 61 0.020
phagocytosis GO:0006909 66 0.020
cellular response to growth factor stimulus GO:0071363 197 0.020
cellular response to organonitrogen compound GO:0071417 145 0.020
cellular metal ion homeostasis GO:0006875 151 0.020
protein localization to organelle GO:0033365 185 0.020
axonogenesis GO:0007409 274 0.020
epithelial tube morphogenesis GO:0060562 303 0.019
germ cell development GO:0007281 185 0.019
monocarboxylic acid metabolic process GO:0032787 191 0.019
glycoprotein biosynthetic process GO:0009101 89 0.019
ensheathment of neurons GO:0007272 76 0.019
negative regulation of t cell proliferation GO:0042130 38 0.019
purine ribonucleoside metabolic process GO:0046128 241 0.019
carbohydrate homeostasis GO:0033500 128 0.019
ossification GO:0001503 216 0.019
regulation of antigen receptor mediated signaling pathway GO:0050854 29 0.019
Mouse
protein catabolic process GO:0030163 221 0.019
positive regulation of reactive oxygen species metabolic process GO:2000379 11 0.019
blood vessel morphogenesis GO:0048514 285 0.019
regulation of adaptive immune response GO:0002819 90 0.019
positive regulation of cell motility GO:2000147 116 0.019
leukocyte migration GO:0050900 124 0.019
stress activated protein kinase signaling cascade GO:0031098 81 0.019
fertilization GO:0009566 127 0.019
negative regulation of leukocyte proliferation GO:0070664 46 0.019
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 55 0.019
protein kinase b signaling GO:0043491 74 0.019
stem cell differentiation GO:0048863 268 0.019
regulation of cell projection organization GO:0031344 206 0.019
regulation of cell motility GO:2000145 236 0.019
regulation of peptide transport GO:0090087 91 0.018
positive regulation of secretion GO:0051047 130 0.018
carboxylic acid transport GO:0046942 100 0.018
cellular response to organic cyclic compound GO:0071407 87 0.018
plasma membrane organization GO:0007009 90 0.018
peptide secretion GO:0002790 114 0.018
t cell mediated immunity GO:0002456 50 0.018
mature dendritic cell differentiation GO:0097029 3 0.018
regulation of protein kinase b signaling GO:0051896 56 0.018
interleukin 2 biosynthetic process GO:0042094 15 0.018
response to inorganic substance GO:0010035 96 0.018
cytosolic calcium ion homeostasis GO:0051480 70 0.018
macromolecule glycosylation GO:0043413 55 0.018
regulation of extrinsic apoptotic signaling pathway GO:2001236 77 0.018
cellular response to external stimulus GO:0071496 88 0.018
protein glycosylation GO:0006486 55 0.018
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.018
purine nucleotide metabolic process GO:0006163 302 0.018
positive regulation of protein kinase b signaling GO:0051897 32 0.018
regulation of t cell differentiation GO:0045580 83 0.017
tissue homeostasis GO:0001894 115 0.017
negative regulation of t cell activation GO:0050868 65 0.017
myelination GO:0042552 74 0.017
detection of stimulus GO:0051606 84 0.017
dna recombination GO:0006310 92 0.017
morphogenesis of a branching structure GO:0001763 203 0.017
extracellular matrix organization GO:0030198 147 0.017
Mouse
spermatogenesis GO:0007283 284 0.017
negative regulation of phosphate metabolic process GO:0045936 184 0.017
adult behavior GO:0030534 135 0.017
regulation of mitotic cell cycle GO:0007346 126 0.017
acute inflammatory response GO:0002526 41 0.017
placenta development GO:0001890 140 0.017
tissue remodeling GO:0048771 102 0.017
Mouse
cell chemotaxis GO:0060326 81 0.017
response to interferon gamma GO:0034341 34 0.017
response to radiation GO:0009314 165 0.017
ribose phosphate metabolic process GO:0019693 291 0.017
regulation of endocytosis GO:0030100 69 0.017
translation GO:0006412 93 0.017
positive regulation of nervous system development GO:0051962 221 0.017
negative regulation of intracellular signal transduction GO:1902532 167 0.017
regulation of interleukin 2 production GO:0032663 28 0.017
osteoclast differentiation GO:0030316 62 0.017
regulation of carbohydrate metabolic process GO:0006109 75 0.017
regulation of peptide secretion GO:0002791 77 0.017
disruption of cells of other organism involved in symbiotic interaction GO:0051818 13 0.016
interaction with symbiont GO:0051702 14 0.016
positive regulation of hydrolase activity GO:0051345 148 0.016
olfactory learning GO:0008355 2 0.016
b cell mediated immunity GO:0019724 71 0.016
nucleocytoplasmic transport GO:0006913 139 0.016
carbohydrate derivative catabolic process GO:1901136 231 0.016
negative regulation of neuron apoptotic process GO:0043524 92 0.016
activation of immune response GO:0002253 138 0.016
Mouse
glial cell differentiation GO:0010001 131 0.016
positive regulation of adaptive immune response GO:0002821 61 0.016
negative regulation of defense response GO:0031348 77 0.016
cellular response to extracellular stimulus GO:0031668 81 0.016
positive regulation of macrophage derived foam cell differentiation GO:0010744 4 0.016
negative regulation of phosphorylation GO:0042326 166 0.016
i kappab kinase nf kappab signaling GO:0007249 85 0.016
t helper 1 type immune response GO:0042088 25 0.016
regulation of stress activated mapk cascade GO:0032872 69 0.016
positive regulation of interleukin 8 production GO:0032757 2 0.016
single organism nuclear import GO:1902593 95 0.016
nucleoside triphosphate metabolic process GO:0009141 230 0.016
axon ensheathment GO:0008366 76 0.016
calcium ion homeostasis GO:0055074 127 0.016
microglia development GO:0014005 2 0.016
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.016
cellular carbohydrate metabolic process GO:0044262 119 0.016
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.015
inflammatory response to antigenic stimulus GO:0002437 30 0.015
peptide transport GO:0015833 133 0.015
negative regulation of apoptotic signaling pathway GO:2001234 104 0.015
defense response to gram positive bacterium GO:0050830 50 0.015
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 52 0.015
nucleoside metabolic process GO:0009116 246 0.015
memory GO:0007613 58 0.015
rhythmic process GO:0048511 174 0.015
myeloid leukocyte mediated immunity GO:0002444 42 0.015
leukocyte apoptotic process GO:0071887 71 0.015
lipid transport GO:0006869 98 0.015
disruption by host of symbiont cells GO:0051852 11 0.015
negative regulation of secretion by cell GO:1903531 54 0.015
reactive oxygen species biosynthetic process GO:1903409 8 0.015
glycosylation GO:0070085 62 0.015
interleukin 2 production GO:0032623 33 0.015
regulation of jnk cascade GO:0046328 62 0.015
protein localization to membrane GO:0072657 108 0.015
lymphocyte homeostasis GO:0002260 64 0.015
superoxide metabolic process GO:0006801 27 0.015
regulation of neuron death GO:1901214 134 0.014
gliogenesis GO:0042063 141 0.014
regulation of mitotic cell cycle phase transition GO:1901990 73 0.014
regulation of chemotaxis GO:0050920 53 0.014
killing of cells in other organism involved in symbiotic interaction GO:0051883 13 0.014
response to peptide GO:1901652 136 0.014
regulation of leukocyte differentiation GO:1902105 159 0.014
nuclear division GO:0000280 158 0.014
morphogenesis of a branching epithelium GO:0061138 193 0.014
purine nucleoside triphosphate catabolic process GO:0009146 203 0.014
growth of symbiont in host GO:0044117 23 0.014
purine ribonucleotide metabolic process GO:0009150 290 0.014
organic cyclic compound catabolic process GO:1901361 295 0.014
modification of morphology or physiology of other organism involved in symbiotic interaction GO:0051817 16 0.014
regulation of peptidyl tyrosine phosphorylation GO:0050730 93 0.014
regulation of erk1 and erk2 cascade GO:0070372 71 0.014
activation of mapk activity GO:0000187 59 0.014
regulation of interleukin 4 biosynthetic process GO:0045402 3 0.014
negative regulation of phosphorus metabolic process GO:0010563 184 0.014
immune response activating signal transduction GO:0002757 116 0.014
Mouse
synaptic transmission GO:0007268 329 0.014
neuron migration GO:0001764 122 0.014
synapse organization GO:0050808 125 0.014
telencephalon development GO:0021537 186 0.014
immune response regulating signaling pathway GO:0002764 125 0.014
Mouse
muscle contraction GO:0006936 101 0.014
negative regulation of protein modification process GO:0031400 163 0.014
regulation of hydrolase activity GO:0051336 246 0.014
positive regulation of alpha beta t cell proliferation GO:0046641 12 0.014
antimicrobial peptide production GO:0002775 2 0.014
chemokine production GO:0032602 34 0.014
positive regulation of protein kinase activity GO:0045860 144 0.014
purine nucleoside triphosphate metabolic process GO:0009144 226 0.014
positive regulation of lymphocyte differentiation GO:0045621 61 0.014
response to growth factor GO:0070848 198 0.014
negative regulation of nervous system development GO:0051961 156 0.014
g protein coupled receptor signaling pathway GO:0007186 243 0.014
microtubule based process GO:0007017 236 0.014
interleukin 12 secretion GO:0072610 3 0.014
positive regulation of chemotaxis GO:0050921 38 0.014
regulation of t cell costimulation GO:2000523 2 0.014
positive regulation of interferon gamma production GO:0032729 39 0.014
immune response regulating cell surface receptor signaling pathway GO:0002768 80 0.013
Mouse
stress activated mapk cascade GO:0051403 80 0.013
dephosphorylation GO:0016311 129 0.013
protein import GO:0017038 101 0.013
bone resorption GO:0045453 38 0.013
positive regulation of cell cycle GO:0045787 92 0.013
pallium development GO:0021543 120 0.013
regulation of lymphocyte differentiation GO:0045619 107 0.013
blood circulation GO:0008015 195 0.013
purine containing compound metabolic process GO:0072521 311 0.013
protein maturation GO:0051604 176 0.013
regulation of cytoplasmic transport GO:1903649 112 0.013
forebrain development GO:0030900 302 0.013
heterocycle catabolic process GO:0046700 280 0.013
regulation of exocytosis GO:0017157 61 0.013
meiotic nuclear division GO:0007126 115 0.013
peptide hormone secretion GO:0030072 109 0.013
organonitrogen compound biosynthetic process GO:1901566 192 0.013
regulation of cysteine type endopeptidase activity GO:2000116 65 0.013
t cell receptor signaling pathway GO:0050852 46 0.013
Mouse
b cell activation GO:0042113 161 0.013
production of molecular mediator of immune response GO:0002440 103 0.013
antimicrobial peptide biosynthetic process GO:0002777 2 0.013
protein import into nucleus GO:0006606 95 0.013
regulation of ossification GO:0030278 112 0.013
oxidation reduction process GO:0055114 342 0.013
organelle assembly GO:0070925 177 0.013
positive regulation of cell migration GO:0030335 109 0.013
positive regulation of t cell costimulation GO:2000525 2 0.013
b cell differentiation GO:0030183 78 0.013
natural killer cell mediated immunity GO:0002228 29 0.013
peptidyl tyrosine modification GO:0018212 145 0.013
interleukin 8 secretion GO:0072606 3 0.013
granulocyte chemotaxis GO:0071621 39 0.013
nucleotide catabolic process GO:0009166 217 0.013
positive regulation of transcription from rna polymerase ii promoter involved in smooth muscle cell differentiation GO:2000721 2 0.013
organonitrogen compound catabolic process GO:1901565 264 0.013
glucose metabolic process GO:0006006 92 0.013
positive regulation of cell adhesion GO:0045785 80 0.013
mammary gland epithelium development GO:0061180 65 0.013
Mouse
activation of innate immune response GO:0002218 56 0.013
response to acid chemical GO:0001101 111 0.013
regulation of angiotensin levels in blood GO:0002002 4 0.013
establishment of protein localization to organelle GO:0072594 118 0.013
purine nucleoside metabolic process GO:0042278 241 0.012
cell maturation GO:0048469 127 0.012
cell cycle g1 s phase transition GO:0044843 57 0.012
regulation of nucleocytoplasmic transport GO:0046822 73 0.012
lipid biosynthetic process GO:0008610 179 0.012
branching morphogenesis of an epithelial tube GO:0048754 159 0.012
positive regulation of cytoplasmic transport GO:1903651 40 0.012
regulation of cellular component size GO:0032535 121 0.012
positive regulation of cytokine secretion GO:0050715 41 0.012
cell junction organization GO:0034330 77 0.012
positive regulation of jnk cascade GO:0046330 46 0.012
regulation of ion homeostasis GO:2000021 64 0.012
alpha beta t cell activation GO:0046631 91 0.012
Mouse
neuron apoptotic process GO:0051402 142 0.012
nuclear import GO:0051170 95 0.012
regulation of endopeptidase activity GO:0052548 89 0.012
positive regulation of proteolysis GO:0045862 85 0.012
respiratory tube development GO:0030323 167 0.012
Mouse
cofactor metabolic process GO:0051186 80 0.012
granulocyte migration GO:0097530 43 0.012
negative regulation of secretion GO:0051048 61 0.012
intracellular protein transport GO:0006886 204 0.012
glycosyl compound metabolic process GO:1901657 246 0.012
circulatory system process GO:0003013 197 0.012
negative regulation of lymphocyte activation GO:0051250 91 0.012
regulation of neuron apoptotic process GO:0043523 122 0.012
receptor mediated endocytosis GO:0006898 51 0.012
actin cytoskeleton organization GO:0030036 220 0.012
meiotic cell cycle process GO:1903046 77 0.012
leukocyte homeostasis GO:0001776 79 0.012
odontogenesis of dentin containing tooth GO:0042475 66 0.012
negative regulation of cytokine production GO:0001818 84 0.012

Spic disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
immune system disease DOID:2914 0 0.032
disease of anatomical entity DOID:7 0 0.032
musculoskeletal system disease DOID:17 0 0.032
connective tissue disease DOID:65 0 0.026
cancer DOID:162 0 0.019
disease of cellular proliferation DOID:14566 0 0.019
bone disease DOID:0080001 0 0.017
nervous system disease DOID:863 0 0.014
organ system cancer DOID:0050686 0 0.012