Mus musculus

0 known processes

Gzmc

granzyme C

(Aliases: Ctla-5,AI323531,Ctla5,CCP2)

Gzmc biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
granzyme mediated apoptotic signaling pathway GO:0008626 1 0.689
Mouse
neutrophil mediated killing of gram positive bacterium GO:0070946 2 0.580
Mouse
immune effector process GO:0002252 321 0.570
Mouse
interleukin 12 secretion GO:0072610 3 0.447
adaptive immune response GO:0002250 155 0.425
Mouse
regulation of angiotensin metabolic process GO:0060177 4 0.380
Mouse
leukocyte mediated immunity GO:0002443 174 0.375
Mouse
cell killing GO:0001906 67 0.373
Mouse
lymphocyte mediated immunity GO:0002449 139 0.355
Mouse
regulation of monocyte chemotaxis GO:0090025 3 0.344
regulation of cytokine production GO:0001817 266 0.338
defense response to other organism GO:0098542 197 0.325
Mouse
cytokine production GO:0001816 319 0.300
regulation of innate immune response GO:0045088 91 0.262
regulation of defense response GO:0031347 233 0.260
cellular response to cytokine stimulus GO:0071345 189 0.252
defense response to gram positive bacterium GO:0050830 50 0.237
Mouse
cell type specific apoptotic process GO:0097285 268 0.219
disruption by host of symbiont cells GO:0051852 11 0.205
Mouse
leukocyte mediated cytotoxicity GO:0001909 62 0.194
Mouse
regulation of angiotensin levels in blood GO:0002002 4 0.181
Mouse
positive regulation of t cell activation GO:0050870 101 0.179
positive regulation of lymphocyte activation GO:0051251 140 0.177
response to molecule of bacterial origin GO:0002237 143 0.164
Mouse
positive regulation of lymphocyte proliferation GO:0050671 70 0.162
regulation of systemic arterial blood pressure GO:0003073 61 0.161
Mouse
defense response to bacterium GO:0042742 119 0.158
Mouse
killing by host of symbiont cells GO:0051873 11 0.151
Mouse
positive regulation of monocyte chemotaxis GO:0090026 2 0.145
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.145
Mouse
alpha beta t cell activation involved in immune response GO:0002287 31 0.143
positive regulation of natural killer cell mediated immunity GO:0002717 16 0.142
positive regulation of leukocyte proliferation GO:0070665 73 0.137
regulation of hydrolase activity GO:0051336 246 0.137
regulation of cytokine secretion GO:0050707 61 0.130
positive regulation of programmed cell death GO:0043068 218 0.130
endocrine process GO:0050886 39 0.126
Mouse
symbiosis encompassing mutualism through parasitism GO:0044403 83 0.125
Mouse
neutrophil mediated killing of symbiont cell GO:0070943 8 0.125
Mouse
positive regulation of defense response GO:0031349 124 0.123
regulation of transferase activity GO:0051338 263 0.119
myeloid leukocyte mediated immunity GO:0002444 42 0.118
Mouse
regulation of kinase activity GO:0043549 249 0.115
mature dendritic cell differentiation GO:0097029 3 0.113
regulation of protein transport GO:0051223 163 0.113
positive regulation of immune effector process GO:0002699 107 0.108
positive regulation of cell death GO:0010942 224 0.108
cytokine secretion GO:0050663 72 0.107
t cell mediated cytotoxicity GO:0001913 26 0.107
Mouse
leukocyte activation involved in immune response GO:0002366 126 0.107
positive regulation of cytokine production GO:0001819 174 0.107
positive regulation of cd4 positive alpha beta t cell proliferation GO:2000563 1 0.106
myeloid cell differentiation GO:0030099 233 0.106
regulation of leukocyte differentiation GO:1902105 159 0.106
stimulatory c type lectin receptor signaling pathway GO:0002223 2 0.102
regulation of leukocyte mediated immunity GO:0002703 104 0.101
regulation of eosinophil migration GO:2000416 2 0.100
regulation of leukocyte proliferation GO:0070663 121 0.098
regulation of t cell proliferation GO:0042129 92 0.097
response to lipopolysaccharide GO:0032496 128 0.092
Mouse
cell activation involved in immune response GO:0002263 126 0.091
positive regulation of kinase activity GO:0033674 155 0.090
activation of immune response GO:0002253 138 0.090
circulatory system process GO:0003013 197 0.090
Mouse
regulation of cellular response to stress GO:0080135 159 0.089
lymphocyte proliferation GO:0046651 164 0.088
regulation of establishment of protein localization GO:0070201 181 0.088
carbohydrate derivative biosynthetic process GO:1901137 183 0.087
regulation of systemic arterial blood pressure by renin angiotensin GO:0003081 20 0.087
Mouse
positive regulation of leukocyte mediated cytotoxicity GO:0001912 31 0.086
negative regulation of multi organism process GO:0043901 68 0.086
Mouse
protein processing GO:0016485 163 0.084
regulation of interleukin 10 secretion GO:2001179 4 0.084
positive regulation of t helper 1 cell differentiation GO:0045627 4 0.083
t cell proliferation GO:0042098 120 0.083
negative regulation of angiogenesis GO:0016525 25 0.082
alpha beta t cell activation GO:0046631 91 0.078
regulation of lymphocyte proliferation GO:0050670 117 0.077
macromolecule catabolic process GO:0009057 281 0.077
t helper cell differentiation GO:0042093 28 0.076
negative regulation of vasculature development GO:1901343 26 0.076
regulation of cd8 positive alpha beta t cell extravasation GO:2000449 3 0.076
neutrophil mediated cytotoxicity GO:0070942 8 0.076
Mouse
cellular response to lipid GO:0071396 145 0.074
negative regulation of macrophage apoptotic process GO:2000110 3 0.073
positive regulation of thymocyte migration GO:2000412 2 0.073
regulation of alpha beta t cell proliferation GO:0046640 18 0.072
t cell differentiation GO:0030217 174 0.072
neuronal action potential GO:0019228 54 0.072
regulation of secretion by cell GO:1903530 249 0.072
apoptotic signaling pathway GO:0097190 306 0.071
Mouse
innate immune response GO:0045087 157 0.070
regulation of cell activation GO:0050865 289 0.070
positive regulation of t cell proliferation GO:0042102 52 0.069
myeloid leukocyte differentiation GO:0002573 119 0.068
leukocyte differentiation GO:0002521 342 0.068
myotube differentiation GO:0014902 105 0.067
leukocyte apoptotic process GO:0071887 71 0.066
positive regulation of t cell costimulation GO:2000525 2 0.064
killing of cells in other organism involved in symbiotic interaction GO:0051883 13 0.064
Mouse
positive regulation of cell killing GO:0031343 33 0.064
negative regulation of growth GO:0045926 99 0.063
Mouse
t cell costimulation GO:0031295 14 0.063
regulation of cd4 positive alpha beta t cell proliferation GO:2000561 2 0.062
regulation of adaptive immune response GO:0002819 90 0.062
regulation of alpha beta t cell activation GO:0046634 53 0.062
cytoplasmic transport GO:0016482 234 0.062
immune response activating cell surface receptor signaling pathway GO:0002429 72 0.062
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 87 0.061
eosinophil migration GO:0072677 3 0.061
small gtpase mediated signal transduction GO:0007264 97 0.061
regulation of protein localization GO:0032880 231 0.061
regulation of response to wounding GO:1903034 189 0.061
immune response regulating signaling pathway GO:0002764 125 0.060
lymphocyte activation involved in immune response GO:0002285 93 0.060
regulation of cytokine biosynthetic process GO:0042035 59 0.060
regulation of skeletal muscle fiber development GO:0048742 36 0.060
nitrogen compound transport GO:0071705 271 0.059
chemotaxis GO:0006935 247 0.059
positive regulation of cell activation GO:0050867 158 0.059
regulation of t cell activation GO:0050863 170 0.059
sequestering of calcium ion GO:0051208 18 0.059
disruption of cells of other organism involved in symbiotic interaction GO:0051818 13 0.058
Mouse
t cell activation involved in immune response GO:0002286 43 0.058
positive regulation of eosinophil migration GO:2000418 2 0.056
cellular homeostasis GO:0019725 240 0.056
regulation of blood pressure GO:0008217 93 0.056
Mouse
muscle cell differentiation GO:0042692 261 0.056
regulation of lymphocyte differentiation GO:0045619 107 0.054
positive regulation of secretion GO:0051047 130 0.054
blood circulation GO:0008015 195 0.053
Mouse
regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 33 0.053
Mouse
g protein coupled receptor signaling pathway GO:0007186 243 0.053
cell cell recognition GO:0009988 44 0.053
regulation of growth of symbiont in host GO:0044126 19 0.053
Mouse
myeloid cell apoptotic process GO:0033028 22 0.052
positive regulation of inflammatory response GO:0050729 47 0.051
regulation of myotube differentiation GO:0010830 62 0.051
growth of symbiont in host GO:0044117 23 0.051
Mouse
regulation of reactive oxygen species metabolic process GO:2000377 40 0.051
protein maturation GO:0051604 176 0.050
ossification GO:0001503 216 0.050
cation homeostasis GO:0055080 212 0.050
modulation of growth of symbiont involved in interaction with host GO:0044144 19 0.050
Mouse
positive regulation of protein phosphorylation GO:0001934 242 0.050
t cell activation GO:0042110 289 0.049
regulation of ion homeostasis GO:2000021 64 0.049
transforming growth factor beta secretion GO:0038044 1 0.048
purine containing compound metabolic process GO:0072521 311 0.048
regulation of leukocyte mediated cytotoxicity GO:0001910 38 0.048
regulation of lymphocyte mediated immunity GO:0002706 84 0.048
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 52 0.048
Mouse
t helper 2 cell cytokine production GO:0035745 4 0.048
regulation of protein secretion GO:0050708 82 0.047
positive regulation of transferase activity GO:0051347 167 0.047
norepinephrine transport GO:0015874 2 0.047
thymocyte migration GO:0072679 2 0.047
leukocyte proliferation GO:0070661 172 0.047
positive regulation of production of molecular mediator of immune response GO:0002702 45 0.047
reactive oxygen species metabolic process GO:0072593 84 0.046
regulation of secretion GO:0051046 274 0.046
regulation of apoptotic signaling pathway GO:2001233 197 0.046
metal ion homeostasis GO:0055065 189 0.045
regulation of thymocyte migration GO:2000410 2 0.045
cd4 positive alpha beta t cell differentiation involved in immune response GO:0002294 28 0.045
regulation of hormone levels GO:0010817 211 0.044
Mouse
nucleotide metabolic process GO:0009117 332 0.044
t helper 1 type immune response GO:0042088 25 0.044
regulation of rho protein signal transduction GO:0035023 71 0.044
positive regulation of alpha beta t cell activation GO:0046635 39 0.044
nucleobase containing small molecule metabolic process GO:0055086 352 0.043
cd8 positive alpha beta t cell extravasation GO:0035697 3 0.043
regulation of mapk cascade GO:0043408 248 0.043
cell recognition GO:0008037 83 0.043
cd4 positive alpha beta t cell differentiation GO:0043367 41 0.043
regulation of systemic arterial blood pressure by circulatory renin angiotensin GO:0001991 13 0.042
Mouse
production of molecular mediator of immune response GO:0002440 103 0.042
regulation of myoblast differentiation GO:0045661 29 0.042
regulation of cell motility GO:2000145 236 0.042
positive regulation of immunoglobulin production in mucosal tissue GO:2000558 1 0.042
positive regulation of interferon gamma production GO:0032729 39 0.042
positive regulation of leukocyte differentiation GO:1902107 86 0.042
negative regulation of myoblast differentiation GO:0045662 18 0.041
eosinophil activation involved in immune response GO:0002278 1 0.041
protein secretion GO:0009306 111 0.041
regulation of angiogenesis GO:0045765 81 0.041
regulation of transforming growth factor beta secretion GO:2001201 1 0.041
regulation of protein kinase activity GO:0045859 232 0.041
positive regulation of lymphocyte mediated immunity GO:0002708 62 0.040
regulation of homeostatic process GO:0032844 182 0.040
positive regulation of innate immune response GO:0045089 80 0.040
cellular divalent inorganic cation homeostasis GO:0072503 127 0.040
cellular nitrogen compound catabolic process GO:0044270 280 0.040
immune response activating signal transduction GO:0002757 116 0.040
immune response regulating cell surface receptor signaling pathway GO:0002768 80 0.040
lymphocyte differentiation GO:0030098 242 0.040
positive regulation of glycoprotein biosynthetic process involved in immunological synapse formation GO:2000526 1 0.039
negative regulation of endothelial cell migration GO:0010596 4 0.039
cd4 positive alpha beta t cell cytokine production GO:0035743 4 0.039
response to organic cyclic compound GO:0014070 198 0.039
regulation of cellular amino acid metabolic process GO:0006521 5 0.039
negative regulation of blood vessel endothelial cell migration GO:0043537 3 0.039
natural killer cell chemotaxis GO:0035747 1 0.039
tumor necrosis factor superfamily cytokine production GO:0071706 51 0.039
skeletal muscle organ development GO:0060538 163 0.039
t cell differentiation involved in immune response GO:0002292 30 0.039
response to growth factor GO:0070848 198 0.039
regulation of natural killer cell chemotaxis GO:2000501 1 0.039
regulation of t helper 1 type immune response GO:0002825 17 0.039
striated muscle cell development GO:0055002 125 0.038
regulation of interferon gamma production GO:0032649 57 0.038
acute inflammatory response GO:0002526 41 0.038
blood vessel morphogenesis GO:0048514 285 0.038
t helper 1 cell cytokine production GO:0035744 1 0.038
nucleotide catabolic process GO:0009166 217 0.038
protein catabolic process GO:0030163 221 0.038
myotube cell development GO:0014904 60 0.038
release of sequestered calcium ion into cytosol GO:0051209 42 0.037
regulation of lymphocyte activation GO:0051249 240 0.037
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.037
positive regulation of secretion by cell GO:1903532 114 0.037
mammary gland epithelium development GO:0061180 65 0.036
angiogenesis GO:0001525 201 0.036
regulation of intracellular transport GO:0032386 159 0.036
cd4 positive alpha beta t cell activation GO:0035710 45 0.036
regulation of cysteine type endopeptidase activity GO:2000116 65 0.036
morphogenesis of a branching epithelium GO:0061138 193 0.036
cellular response to amino acid stimulus GO:0071230 29 0.036
cellular response to acid chemical GO:0071229 68 0.035
negative regulation of hydrolase activity GO:0051346 71 0.035
regulation of tumor necrosis factor superfamily cytokine production GO:1903555 50 0.035
positive regulation of cd8 positive alpha beta t cell extravasation GO:2000451 2 0.035
positive regulation of natural killer cell mediated cytotoxicity GO:0045954 16 0.035
regulation of cellular ketone metabolic process GO:0010565 66 0.034
cellular response to organonitrogen compound GO:0071417 145 0.034
glycoprotein biosynthetic process GO:0009101 89 0.034
response to extracellular stimulus GO:0009991 127 0.034
positive regulation of transforming growth factor beta secretion GO:2001203 1 0.034
regulation of epithelial cell proliferation GO:0050678 141 0.034
skeletal muscle fiber development GO:0048741 58 0.034
intrinsic apoptotic signaling pathway GO:0097193 132 0.034
positive regulation of alpha beta t cell proliferation GO:0046641 12 0.034
positive regulation of cellular amine metabolic process GO:0033240 5 0.033
calcium ion transport GO:0006816 159 0.033
regulation of nucleotide metabolic process GO:0006140 169 0.033
t cell extravasation GO:0072683 4 0.033
sequestering of metal ion GO:0051238 19 0.033
epithelial cell proliferation GO:0050673 174 0.033
regulation of proteolysis GO:0030162 164 0.033
interferon gamma production GO:0032609 67 0.033
peptide transport GO:0015833 133 0.032
response to nutrient levels GO:0031667 109 0.032
norepinephrine secretion GO:0048243 2 0.032
nucleoside phosphate metabolic process GO:0006753 338 0.032
natural killer cell mediated immunity GO:0002228 29 0.032
natural killer cell activation GO:0030101 44 0.032
regulation of protein serine threonine kinase activity GO:0071900 157 0.032
cellular response to hormone stimulus GO:0032870 150 0.032
leukocyte chemotaxis GO:0030595 69 0.031
positive regulation of t helper 1 cell cytokine production GO:2000556 1 0.031
response to organonitrogen compound GO:0010243 246 0.031
positive regulation of hydrolase activity GO:0051345 148 0.031
cellular response to lipopolysaccharide GO:0071222 77 0.031
single organism nuclear import GO:1902593 95 0.030
neuron apoptotic process GO:0051402 142 0.030
cd4 positive alpha beta t cell proliferation GO:0035739 2 0.030
natural killer cell mediated cytotoxicity GO:0042267 29 0.030
cellular response to biotic stimulus GO:0071216 92 0.030
interleukin 10 secretion GO:0072608 4 0.030
negative regulation of immune system process GO:0002683 209 0.030
regulation of leukocyte apoptotic process GO:2000106 56 0.030
ribonucleotide metabolic process GO:0009259 291 0.030
action potential GO:0001508 78 0.030
cell chemotaxis GO:0060326 81 0.030
interspecies interaction between organisms GO:0044419 83 0.029
Mouse
growth of symbiont involved in interaction with host GO:0044116 23 0.029
Mouse
eosinophil activation GO:0043307 1 0.029
ribose phosphate metabolic process GO:0019693 291 0.029
defense response to virus GO:0051607 68 0.029
reactive nitrogen species metabolic process GO:2001057 0 0.029
heterocycle catabolic process GO:0046700 280 0.029
t cell mediated immunity GO:0002456 50 0.029
Mouse
muscle fiber development GO:0048747 76 0.029
dendritic cell dendrite assembly GO:0097026 2 0.029
positive regulation of leukocyte mediated immunity GO:0002705 70 0.029
killing of cells of other organism GO:0031640 13 0.029
Mouse
cellular ion homeostasis GO:0006873 165 0.029
regulation of natural killer cell mediated immunity GO:0002715 19 0.028
multicellular organismal signaling GO:0035637 91 0.028
regulation of chemotaxis GO:0050920 53 0.028
neuron death GO:0070997 154 0.028
cellular chemical homeostasis GO:0055082 215 0.028
positive regulation of interleukin 12 production GO:0032735 21 0.028
reactive oxygen species biosynthetic process GO:1903409 8 0.028
response to peptide GO:1901652 136 0.027
rho protein signal transduction GO:0007266 32 0.027
negative regulation of leukocyte apoptotic process GO:2000107 31 0.027
positive regulation of protein secretion GO:0050714 52 0.027
positive regulation of cell migration GO:0030335 109 0.027
regulation of b cell chemotaxis GO:2000537 2 0.027
inflammatory cell apoptotic process GO:0006925 11 0.027
positive regulation of dendritic cell dendrite assembly GO:2000549 1 0.027
negative regulation of apoptotic signaling pathway GO:2001234 104 0.027
purine ribonucleoside metabolic process GO:0046128 241 0.027
type 2 immune response GO:0042092 23 0.027
regulation of t cell differentiation GO:0045580 83 0.027
cellular response to growth factor stimulus GO:0071363 197 0.027
positive regulation of t helper 2 cell cytokine production GO:2000553 3 0.027
negative regulation of phosphate metabolic process GO:0045936 184 0.027
negative regulation of phosphorus metabolic process GO:0010563 184 0.027
glycosyl compound metabolic process GO:1901657 246 0.026
regulation of cellular amine metabolic process GO:0033238 20 0.026
granulocyte chemotaxis GO:0071621 39 0.026
placenta development GO:0001890 140 0.026
striated muscle tissue development GO:0014706 293 0.026
myelination GO:0042552 74 0.026
negative regulation of homeostatic process GO:0032845 71 0.026
mature natural killer cell chemotaxis GO:0035782 1 0.026
regulation of t helper cell differentiation GO:0045622 14 0.026
positive regulation of apoptotic process GO:0043065 217 0.026
organonitrogen compound biosynthetic process GO:1901566 192 0.026
positive regulation of immunological synapse formation GO:2000522 1 0.026
dendritic cell chemotaxis GO:0002407 7 0.026
positive regulation of natural killer cell chemotaxis GO:2000503 1 0.026
cellular response to molecule of bacterial origin GO:0071219 83 0.026
negative regulation of protein processing GO:0010955 79 0.025
negative regulation of growth of symbiont in host GO:0044130 19 0.025
Mouse
immunoglobulin mediated immune response GO:0016064 69 0.025
purine ribonucleotide metabolic process GO:0009150 290 0.025
detection of yeast GO:0001879 2 0.025
regulation of myeloid cell apoptotic process GO:0033032 19 0.025
regulation of t helper 2 cell cytokine production GO:2000551 3 0.025
t cell differentiation in thymus GO:0033077 77 0.025
disruption of cells of other organism GO:0044364 13 0.025
Mouse
regulation of circadian sleep wake cycle GO:0042749 3 0.025
purine nucleoside metabolic process GO:0042278 241 0.025
morphogenesis of a branching structure GO:0001763 203 0.025
positive regulation of protein kinase activity GO:0045860 144 0.025
astrocyte cell migration GO:0043615 3 0.025
organ or tissue specific immune response GO:0002251 13 0.025
calcium ion homeostasis GO:0055074 127 0.025
gtp metabolic process GO:0046039 144 0.025
response to peptide hormone GO:0043434 127 0.025
branching involved in mammary gland duct morphogenesis GO:0060444 27 0.025
eosinophil degranulation GO:0043308 1 0.025
glycoprotein metabolic process GO:0009100 116 0.025
myoblast differentiation GO:0045445 52 0.025
response to molecule of fungal origin GO:0002238 4 0.024
regulation of alpha beta t cell differentiation GO:0046637 35 0.024
endomembrane system organization GO:0010256 147 0.024
cdc42 protein signal transduction GO:0032488 0 0.024
response to amino acid GO:0043200 37 0.024
inflammatory response GO:0006954 244 0.024
regulation of immunoglobulin production in mucosal tissue GO:2000557 1 0.024
aromatic compound catabolic process GO:0019439 286 0.024
positive regulation of tumor necrosis factor production GO:0032760 30 0.024
cellular amine metabolic process GO:0044106 44 0.024
interleukin 1 production GO:0032612 31 0.024
divalent inorganic cation homeostasis GO:0072507 138 0.024
cellular ketone metabolic process GO:0042180 84 0.024
regulation of natural killer cell mediated cytotoxicity GO:0042269 19 0.024
response to insulin GO:0032868 100 0.024
positive regulation of adaptive immune response GO:0002821 61 0.024
regulation of systemic arterial blood pressure by hormone GO:0001990 25 0.024
Mouse
positive regulation of angiogenesis GO:0045766 46 0.024
regulation of t cell costimulation GO:2000523 2 0.024
negative regulation of response to wounding GO:1903035 77 0.024
negative regulation of myeloid cell apoptotic process GO:0033033 11 0.024
regulation of immunological synapse formation GO:2000520 2 0.024
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.024
positive regulation of cytokine secretion GO:0050715 41 0.023
negative regulation of cellular protein metabolic process GO:0032269 247 0.023
regulation of microvillus assembly GO:0032534 3 0.023
nucleoside metabolic process GO:0009116 246 0.023
positive regulation of epithelial cell proliferation GO:0050679 68 0.023
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.023
cytosolic calcium ion homeostasis GO:0051480 70 0.023
cytokine metabolic process GO:0042107 71 0.023
cellular lipid metabolic process GO:0044255 323 0.023
endocytosis GO:0006897 168 0.023
positive regulation of alpha beta t cell differentiation GO:0046638 28 0.023
dendritic cell differentiation GO:0097028 26 0.023
t helper 1 cell differentiation GO:0045063 13 0.023
cytokine mediated signaling pathway GO:0019221 115 0.023
regulation of multi organism process GO:0043900 111 0.022
Mouse
purine ribonucleotide catabolic process GO:0009154 208 0.022
positive regulation of cell motility GO:2000147 116 0.022
pattern recognition receptor signaling pathway GO:0002221 47 0.022
regulation of striated muscle cell differentiation GO:0051153 81 0.022
neutrophil mediated killing of bacterium GO:0070944 6 0.022
Mouse
positive regulation of nucleotide metabolic process GO:0045981 114 0.022
tumor necrosis factor production GO:0032640 50 0.022
organic cyclic compound catabolic process GO:1901361 295 0.022
activation of innate immune response GO:0002218 56 0.022
response to acid chemical GO:0001101 111 0.022
regulation of t cell extravasation GO:2000407 3 0.022
response to drug GO:0042493 75 0.022
regulation of dendritic cell chemotaxis GO:2000508 1 0.022
regulation of cell killing GO:0031341 40 0.022
positive regulation of protein modification process GO:0031401 299 0.022
innate immune response activating cell surface receptor signaling pathway GO:0002220 4 0.022
nucleoside phosphate biosynthetic process GO:1901293 79 0.021
negative regulation of defense response GO:0031348 77 0.021
immunoglobulin production in mucosal tissue GO:0002426 3 0.021
positive regulation of t helper 1 type immune response GO:0002827 12 0.021
leukocyte migration GO:0050900 124 0.021
myeloid leukocyte activation GO:0002274 83 0.021
amine metabolic process GO:0009308 45 0.021
regulation of t helper 1 cell cytokine production GO:2000554 1 0.021
axon ensheathment GO:0008366 76 0.021
positive regulation of dendritic cell chemotaxis GO:2000510 1 0.021
osteoclast differentiation GO:0030316 62 0.021
mammary gland duct morphogenesis GO:0060603 38 0.021
interleukin 2 production GO:0032623 33 0.021
stress activated mapk cascade GO:0051403 80 0.021
regulation of endocytosis GO:0030100 69 0.021
purine nucleotide catabolic process GO:0006195 211 0.021
cellular amino acid metabolic process GO:0006520 103 0.021
carbohydrate derivative catabolic process GO:1901136 231 0.020
cellular metal ion homeostasis GO:0006875 151 0.020
peptidyl amino acid modification GO:0018193 336 0.020
purine nucleotide metabolic process GO:0006163 302 0.020
positive regulation of type 2 immune response GO:0002830 9 0.020
cytokine production involved in immune response GO:0002367 34 0.020
cellular response to molecule of fungal origin GO:0071226 2 0.020
maintenance of location GO:0051235 89 0.020
regulation of system process GO:0044057 200 0.020
nuclear transport GO:0051169 139 0.020
negative regulation of cytokine production GO:0001818 84 0.020
regulation of production of molecular mediator of immune response GO:0002700 65 0.020
negative regulation of intracellular signal transduction GO:1902532 167 0.020
ensheathment of neurons GO:0007272 76 0.020
regulation of dendritic cell dendrite assembly GO:2000547 2 0.020
purine containing compound catabolic process GO:0072523 213 0.020
membrane depolarization GO:0051899 64 0.020
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.020
regulation of tumor necrosis factor production GO:0032680 49 0.020
regulation of membrane potential GO:0042391 192 0.019
regulation of ossification GO:0030278 112 0.019
regulation of cell migration GO:0030334 219 0.019
antigen processing and presentation GO:0019882 47 0.019
helper t cell chemotaxis GO:0035704 1 0.019
vasodilation GO:0042311 28 0.019
regulation of blood circulation GO:1903522 93 0.019
extracellular matrix organization GO:0030198 147 0.019
interleukin 1 secretion GO:0050701 16 0.019
negative regulation of immune effector process GO:0002698 55 0.019
regulation of t helper 1 cell differentiation GO:0045625 7 0.019
peptidyl tyrosine phosphorylation GO:0018108 143 0.019
muscle cell development GO:0055001 133 0.019
lymphocyte costimulation GO:0031294 15 0.019
ribonucleotide catabolic process GO:0009261 208 0.019
negative regulation of mitotic cell cycle GO:0045930 58 0.019
negative regulation of muscle cell differentiation GO:0051148 33 0.019
regulation of protein maturation GO:1903317 96 0.019
developmental growth involved in morphogenesis GO:0060560 138 0.019
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.019
regulation of inflammatory response GO:0050727 147 0.019
eosinophil mediated immunity GO:0002447 1 0.019
nucleoside triphosphate catabolic process GO:0009143 205 0.019
ribonucleoside metabolic process GO:0009119 245 0.019
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.018
regulation of osteoclast differentiation GO:0045670 36 0.018
receptor mediated endocytosis GO:0006898 51 0.018
regulation of cellular component biogenesis GO:0044087 181 0.018
negative regulation of cell motility GO:2000146 61 0.018
learning or memory GO:0007611 148 0.018
embryonic placenta development GO:0001892 98 0.018
negative regulation of phosphorylation GO:0042326 166 0.018
organic hydroxy compound metabolic process GO:1901615 203 0.018
cellular response to peptide GO:1901653 92 0.018
regulation of muscle tissue development GO:1901861 97 0.018
peptide metabolic process GO:0006518 46 0.018
microglial cell activation involved in immune response GO:0002282 1 0.018
growth involved in symbiotic interaction GO:0044110 23 0.018
Mouse
developmental maturation GO:0021700 193 0.018
gland development GO:0048732 330 0.018
branching morphogenesis of an epithelial tube GO:0048754 159 0.018
regulation of interleukin 1 beta secretion GO:0050706 15 0.018
b cell activation GO:0042113 161 0.018
dephosphorylation GO:0016311 129 0.018
cytokine biosynthetic process GO:0042089 68 0.017
negative regulation of cell cycle GO:0045786 123 0.017
positive regulation of tumor necrosis factor superfamily cytokine production GO:1903557 31 0.017
fat cell differentiation GO:0045444 160 0.017
interleukin 1 beta production GO:0032611 30 0.017
posttranscriptional regulation of gene expression GO:0010608 155 0.017
nucleocytoplasmic transport GO:0006913 139 0.017
alpha beta t cell differentiation involved in immune response GO:0002293 30 0.017
positive regulation of mapk cascade GO:0043410 170 0.017
positive regulation of stress activated mapk cascade GO:0032874 48 0.017
neutrophil mediated immunity GO:0002446 19 0.017
Mouse
regulation of cellular catabolic process GO:0031329 242 0.017
regulation of cd4 positive alpha beta t cell activation GO:2000514 24 0.017

Gzmc disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.040
nervous system disease DOID:863 0 0.040
central nervous system disease DOID:331 0 0.021
neurodegenerative disease DOID:1289 0 0.021
musculoskeletal system disease DOID:17 0 0.020