Mus musculus

78 known processes

Htr1a

5-hydroxytryptamine (serotonin) receptor 1A

(Aliases: Gpcr18)

Htr1a biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
synaptic transmission GO:0007268 329 0.980
Mouse
protein kinase c activating g protein coupled receptor signaling pathway GO:0007205 4 0.960
Mouse
g protein coupled receptor signaling pathway GO:0007186 243 0.941
histamine induced gastric acid secretion GO:0001697 1 0.865
Mouse
conditioned taste aversion GO:0001661 4 0.826
Mouse
vasodilation by norepinephrine epinephrine involved in regulation of systemic arterial blood pressure GO:0002025 3 0.764
Mouse
adenylate cyclase modulating g protein coupled receptor signaling pathway GO:0007188 54 0.757
Human Mouse Rat
locomotory behavior GO:0007626 195 0.738
Mouse
phospholipase c activating g protein coupled receptor signaling pathway GO:0007200 26 0.736
Mouse
associative learning GO:0008306 61 0.728
Mouse
neuropeptide signaling pathway GO:0007218 19 0.658
cation transport GO:0006812 399 0.610
divalent metal ion transport GO:0070838 172 0.601
regulation of membrane potential GO:0042391 192 0.592
Mouse
action potential GO:0001508 78 0.584
Mouse
cellular response to temperature stimulus GO:0071502 2 0.584
Mouse
cellular amine metabolic process GO:0044106 44 0.575
regulation of blood pressure GO:0008217 93 0.557
Mouse
amine metabolic process GO:0009308 45 0.556
regulation of synaptic plasticity GO:0048167 87 0.547
Mouse
circadian rhythm GO:0007623 114 0.540
somatostatin signaling pathway GO:0038170 2 0.530
nitrogen compound transport GO:0071705 271 0.526
somatostatin receptor signaling pathway GO:0038169 2 0.524
learning GO:0007612 98 0.519
Mouse
regulation of serotonin secretion GO:0014062 3 0.504
response to light stimulus GO:0009416 135 0.503
Mouse
regulation of saliva secretion GO:0046877 2 0.498
multicellular organismal response to stress GO:0033555 62 0.486
adenylate cyclase activating g protein coupled receptor signaling pathway GO:0007189 30 0.478
Mouse
ion transmembrane transport GO:0034220 361 0.468
tissue remodeling GO:0048771 102 0.442
Mouse
positive regulation of heart rate GO:0010460 10 0.441
Mouse
regulation of camp biosynthetic process GO:0030817 25 0.437
Mouse
positive regulation of glycolytic process GO:0045821 4 0.433
Mouse
cognition GO:0050890 149 0.426
Mouse
phospholipase c activating serotonin receptor signaling pathway GO:0007208 1 0.423
Mouse
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger GO:0007187 55 0.413
Human Mouse Rat
cellular chemical homeostasis GO:0055082 215 0.413
Mouse
rhythmic process GO:0048511 174 0.409
regulation of cellular amine metabolic process GO:0033238 20 0.391
cation homeostasis GO:0055080 212 0.389
Mouse
operant conditioning GO:0035106 2 0.375
Mouse
glial cell differentiation GO:0010001 131 0.370
Mouse
hormone secretion GO:0046879 128 0.365
Mouse
adenylate cyclase inhibiting g protein coupled receptor signaling pathway GO:0007193 20 0.359
Human Rat
transmission of nerve impulse GO:0019226 76 0.358
Mouse
multicellular organismal signaling GO:0035637 91 0.357
Mouse
regulation of postsynaptic membrane potential GO:0060078 48 0.356
regulation of hormone secretion GO:0046883 88 0.350
Mouse
transmembrane transport GO:0055085 412 0.347
regulation of camp metabolic process GO:0030814 30 0.344
Mouse
regulation of ion transport GO:0043269 215 0.344
adult behavior GO:0030534 135 0.343
Mouse
cellular ketone metabolic process GO:0042180 84 0.343
regulation of hormone levels GO:0010817 211 0.341
Mouse
positive regulation of cytosolic calcium ion concentration involved in phospholipase c activating g protein coupled signaling pathway GO:0051482 4 0.332
Mouse
amide transport GO:0042886 138 0.317
Mouse
response to nutrient levels GO:0031667 109 0.316
Mouse
regulation of excitatory postsynaptic membrane potential GO:0060079 41 0.315
adult locomotory behavior GO:0008344 91 0.302
Mouse
organonitrogen compound biosynthetic process GO:1901566 192 0.297
Mouse
peptide transport GO:0015833 133 0.292
Mouse
regulation of systemic arterial blood pressure by norepinephrine epinephrine GO:0001993 8 0.289
Mouse
response to radiation GO:0009314 165 0.289
Mouse
inorganic ion transmembrane transport GO:0098660 234 0.282
cation transmembrane transport GO:0098655 266 0.279
regulation of neurological system process GO:0031644 22 0.276
Mouse
regulation of metal ion transport GO:0010959 106 0.261
Mouse
regulation of nucleotide biosynthetic process GO:0030808 34 0.260
Mouse
ribose phosphate biosynthetic process GO:0046390 59 0.258
Mouse
regulation of cell migration GO:0030334 219 0.258
Mouse
visual learning GO:0008542 44 0.257
Mouse
regulation of transferase activity GO:0051338 263 0.252
Mouse
circulatory system process GO:0003013 197 0.249
Mouse
positive regulation of the force of heart contraction by chemical signal GO:0003099 3 0.248
Mouse
purine nucleotide biosynthetic process GO:0006164 65 0.244
Mouse
response to organic cyclic compound GO:0014070 198 0.243
Mouse
regulation of purine nucleotide biosynthetic process GO:1900371 34 0.242
Mouse
regulation of cellular ketone metabolic process GO:0010565 66 0.240
corticotropin releasing hormone secretion GO:0043396 2 0.237
Mouse
dopamine metabolic process GO:0042417 23 0.236
generation of precursor metabolites and energy GO:0006091 103 0.235
Mouse
organophosphate biosynthetic process GO:0090407 122 0.232
Mouse
cytoplasmic transport GO:0016482 234 0.232
Mouse
detection of stimulus GO:0051606 84 0.226
gliogenesis GO:0042063 141 0.225
Mouse
g protein coupled receptor internalization GO:0002031 3 0.224
Mouse
camp metabolic process GO:0046058 40 0.220
Mouse
insulin secretion GO:0030073 89 0.220
gastrin induced gastric acid secretion GO:0001698 1 0.219
Mouse
nucleoside phosphate biosynthetic process GO:1901293 79 0.218
Mouse
calcium ion transport GO:0006816 159 0.217
positive regulation of protein modification process GO:0031401 299 0.217
Mouse
negative regulation of cyclic nucleotide metabolic process GO:0030800 5 0.214
Mouse
positive regulation of blood pressure by epinephrine norepinephrine GO:0003321 6 0.208
Mouse
regulation of system process GO:0044057 200 0.203
Mouse
regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 33 0.203
Mouse
response to cocaine GO:0042220 14 0.200
Mouse
response to ammonium ion GO:0060359 21 0.199
Mouse
membrane depolarization GO:0051899 64 0.198
positive regulation of heart rate by epinephrine norepinephrine GO:0001996 4 0.197
Mouse
response to steroid hormone GO:0048545 56 0.196
neuron neuron synaptic transmission GO:0007270 69 0.195
Mouse
positive regulation of transferase activity GO:0051347 167 0.194
Mouse
dopamine receptor signaling pathway GO:0007212 16 0.191
Mouse
ensheathment of neurons GO:0007272 76 0.191
inorganic cation transmembrane transport GO:0098662 207 0.191
feeding behavior GO:0007631 62 0.190
Mouse Rat
negative regulation of serotonin secretion GO:0014063 2 0.189
Mouse
intracellular protein transport GO:0006886 204 0.186
Mouse
regulation of nucleotide metabolic process GO:0006140 169 0.184
Mouse
cellular divalent inorganic cation homeostasis GO:0072503 127 0.181
Mouse
regulation of systemic arterial blood pressure GO:0003073 61 0.181
Mouse
organic hydroxy compound metabolic process GO:1901615 203 0.179
serotonin receptor signaling pathway GO:0007210 8 0.178
negative regulation of purine nucleotide metabolic process GO:1900543 16 0.178
Mouse
fear response GO:0042596 33 0.178
chemotaxis GO:0006935 247 0.177
cyclic nucleotide metabolic process GO:0009187 59 0.176
Mouse
cellular homeostasis GO:0019725 240 0.176
Mouse
adenylate cyclase activating dopamine receptor signaling pathway GO:0007191 7 0.175
Mouse
regulation of cell motility GO:2000145 236 0.174
Mouse
neuron migration GO:0001764 122 0.172
Mouse
neuronal action potential GO:0019228 54 0.172
Mouse
opioid receptor signaling pathway GO:0038003 5 0.170
organic hydroxy compound transport GO:0015850 93 0.169
positive regulation of camp metabolic process GO:0030816 19 0.168
Mouse
cytokine production GO:0001816 319 0.168
Mouse
sensitization GO:0046960 2 0.162
Mouse
learning or memory GO:0007611 148 0.161
Mouse
regulation of cyclic nucleotide metabolic process GO:0030799 40 0.161
Mouse
positive regulation of ion transport GO:0043270 65 0.161
cyclic purine nucleotide metabolic process GO:0052652 43 0.160
Mouse
regulation of secretion by cell GO:1903530 249 0.158
cellular lipid metabolic process GO:0044255 323 0.156
regulation of secretion GO:0051046 274 0.155
glial cell development GO:0021782 54 0.154
Mouse
regulation of cellular amino acid metabolic process GO:0006521 5 0.153
nucleotide biosynthetic process GO:0009165 78 0.151
Mouse
cyclic nucleotide biosynthetic process GO:0009190 44 0.151
Mouse
long term synaptic potentiation GO:0060291 25 0.148
Mouse
acid secretion GO:0046717 33 0.147
Mouse
myelination GO:0042552 74 0.147
monocarboxylic acid metabolic process GO:0032787 191 0.146
Mouse
serotonin metabolic process GO:0042428 8 0.142
negative regulation of nucleotide metabolic process GO:0045980 16 0.141
Mouse
synaptic transmission glutamatergic GO:0035249 36 0.140
Mouse
forebrain development GO:0030900 302 0.139
Mouse
blood circulation GO:0008015 195 0.136
Mouse
sodium ion transport GO:0006814 73 0.135
Mouse
visual behavior GO:0007632 45 0.135
Mouse
calcium ion transmembrane transport GO:0070588 85 0.132
peptide secretion GO:0002790 114 0.131
Mouse
cellular calcium ion homeostasis GO:0006874 119 0.131
Mouse
peptide hormone secretion GO:0030072 109 0.130
Mouse
memory GO:0007613 58 0.129
Mouse
heart contraction GO:0060047 93 0.127
Mouse
glucose homeostasis GO:0042593 128 0.127
positive regulation of blood pressure GO:0045777 21 0.125
Mouse
mapk cascade GO:0000165 281 0.124
Mouse
regulation of peptide secretion GO:0002791 77 0.123
Mouse
positive regulation of secretion by cell GO:1903532 114 0.123
Mouse
adult walking behavior GO:0007628 41 0.123
Mouse
carbohydrate homeostasis GO:0033500 128 0.122
nucleotide metabolic process GO:0009117 332 0.121
Mouse
temperature homeostasis GO:0001659 26 0.119
Mouse
response to alkaloid GO:0043279 34 0.119
Mouse
blood vessel morphogenesis GO:0048514 285 0.118
Mouse
response to extracellular stimulus GO:0009991 127 0.116
Mouse
divalent inorganic cation transport GO:0072511 178 0.115
regulation of peptide transport GO:0090087 91 0.115
Mouse
nucleobase containing small molecule metabolic process GO:0055086 352 0.115
Mouse
regulation of g protein coupled receptor protein signaling pathway GO:0008277 37 0.114
Mouse
calcium ion homeostasis GO:0055074 127 0.113
Mouse
positive regulation of kinase activity GO:0033674 155 0.111
Mouse
behavioral response to cocaine GO:0048148 10 0.110
Mouse
gastric acid secretion GO:0001696 6 0.108
Mouse
bone resorption GO:0045453 38 0.106
Mouse
regulation of protein kinase activity GO:0045859 232 0.106
catecholamine transport GO:0051937 21 0.106
Mouse
negative regulation of ion transport GO:0043271 28 0.105
Mouse
axonogenesis GO:0007409 274 0.103
vascular process in circulatory system GO:0003018 62 0.103
Mouse
regulation of circadian sleep wake cycle rem sleep GO:0042320 1 0.103
regulation of calcium ion transport GO:0051924 69 0.102
regulation of muscle system process GO:0090257 80 0.102
Mouse
regulation of cyclic nucleotide biosynthetic process GO:0030802 31 0.100
Mouse
tissue homeostasis GO:0001894 115 0.099
Mouse
purine ribonucleotide metabolic process GO:0009150 290 0.099
Mouse
regulation of smooth muscle contraction GO:0006940 22 0.099
Mouse
cellular amino acid metabolic process GO:0006520 103 0.099
gland development GO:0048732 330 0.097
Mouse
negative regulation of purine nucleotide biosynthetic process GO:1900372 6 0.096
Mouse
forebrain cell migration GO:0021885 58 0.095
Mouse
response to amphetamine GO:0001975 16 0.095
Mouse
metal ion homeostasis GO:0055065 189 0.095
Mouse
regulation of dopamine metabolic process GO:0042053 10 0.094
monosaccharide transport GO:0015749 58 0.094
Mouse
behavioral defense response GO:0002209 28 0.094
positive regulation of the force of heart contraction by epinephrine norepinephrine GO:0001997 3 0.093
Mouse
positive regulation of protein kinase activity GO:0045860 144 0.093
peptidyl amino acid modification GO:0018193 336 0.092
Mouse
activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 3 0.092
regulation of purine nucleotide metabolic process GO:1900542 169 0.091
Mouse
anion transmembrane transport GO:0098656 71 0.090
negative regulation of camp metabolic process GO:0030815 5 0.090
Mouse
nuclear transport GO:0051169 139 0.089
Mouse
ribose phosphate metabolic process GO:0019693 291 0.089
Mouse
long term synaptic depression GO:0060292 13 0.089
Mouse
divalent inorganic cation homeostasis GO:0072507 138 0.088
Mouse
carbohydrate derivative biosynthetic process GO:1901137 183 0.087
Mouse
response to pain GO:0048265 26 0.087
regulation of ion transmembrane transport GO:0034765 119 0.087
neuron death GO:0070997 154 0.085
angiogenesis GO:0001525 201 0.085
Mouse
monoamine transport GO:0015844 33 0.084
macromolecule catabolic process GO:0009057 281 0.083
negative regulation of secretion by cell GO:1903531 54 0.083
Mouse
detection of abiotic stimulus GO:0009582 60 0.083
desensitization of g protein coupled receptor protein signaling pathway GO:0002029 5 0.083
Mouse
positive regulation of calcium ion transport GO:0051928 27 0.083
regulation of transmembrane transport GO:0034762 128 0.081
regulation of carbohydrate metabolic process GO:0006109 75 0.081
Mouse
membrane hyperpolarization GO:0060081 21 0.081
protein localization to nucleus GO:0034504 121 0.080
Mouse
regulation of circadian sleep wake cycle GO:0042749 3 0.079
sensory perception GO:0007600 245 0.077
protein targeting GO:0006605 143 0.075
Mouse
dopamine transport GO:0015872 15 0.075
Mouse
regulation of neurotransmitter secretion GO:0046928 29 0.075
small molecule biosynthetic process GO:0044283 132 0.075
circadian sleep wake cycle GO:0042745 5 0.074
regulation of lyase activity GO:0051339 13 0.073
Mouse
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.073
protein import into nucleus GO:0006606 95 0.071
Mouse
regulation of feeding behavior GO:0060259 3 0.070
Rat
regulation of kinase activity GO:0043549 249 0.070
Mouse
positive regulation of cell migration GO:0030335 109 0.070
Mouse
regulation of acetylcholine secretion neurotransmission GO:0014056 2 0.070
fat cell differentiation GO:0045444 160 0.069
Mouse
heart morphogenesis GO:0003007 178 0.069
Mouse
regulation of generation of precursor metabolites and energy GO:0043467 38 0.068
Mouse
establishment of protein localization to organelle GO:0072594 118 0.068
Mouse
regulation of circadian sleep wake cycle sleep GO:0045187 3 0.067
carboxylic acid transport GO:0046942 100 0.067
negative regulation of secretion GO:0051048 61 0.067
Mouse
negative regulation of growth GO:0045926 99 0.067
Mouse
single organism nuclear import GO:1902593 95 0.066
Mouse
baroreceptor response to decreased systemic arterial blood pressure GO:0001982 2 0.065
anion transport GO:0006820 177 0.065
regulation of gliogenesis GO:0014013 50 0.065
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.065
Mouse
regulation of tube size GO:0035150 57 0.064
Mouse
hormone mediated signaling pathway GO:0009755 23 0.064
response to alcohol GO:0097305 48 0.064
innate immune response GO:0045087 157 0.064
negative regulation of cyclic nucleotide biosynthetic process GO:0030803 5 0.063
Mouse
hexose metabolic process GO:0019318 98 0.063
l amino acid transport GO:0015807 32 0.063
regulation of cellular carbohydrate metabolic process GO:0010675 75 0.062
Mouse
glutamate receptor signaling pathway GO:0007215 35 0.062
detection of external stimulus GO:0009581 61 0.062
amino acid transmembrane transport GO:0003333 37 0.061
regulation of catecholamine metabolic process GO:0042069 10 0.061
multicellular organism growth GO:0035264 161 0.061
Mouse
glucose transport GO:0015758 56 0.061
Mouse
ameboidal type cell migration GO:0001667 128 0.060
Mouse
amino acid transport GO:0006865 61 0.060
positive regulation of cyclic nucleotide biosynthetic process GO:0030804 24 0.060
Mouse
hexose transport GO:0008645 56 0.060
Mouse
positive regulation of cell death GO:0010942 224 0.059
positive regulation of adenylate cyclase activity involved in g protein coupled receptor signaling pathway GO:0010579 3 0.058
sensory perception of pain GO:0019233 47 0.058
regulation of response to wounding GO:1903034 189 0.057
serotonin secretion GO:0001820 8 0.057
positive regulation of nucleotide metabolic process GO:0045981 114 0.057
Mouse
regulation of mapk cascade GO:0043408 248 0.056
circadian sleep wake cycle rem sleep GO:0042747 1 0.056
behavioral fear response GO:0001662 28 0.056
positive regulation of nucleotide biosynthetic process GO:0030810 26 0.055
Mouse
regulation of neuronal synaptic plasticity GO:0048168 30 0.055
defense response to other organism GO:0098542 197 0.055
purine nucleotide metabolic process GO:0006163 302 0.055
Mouse
regulation of response to drug GO:2001023 2 0.055
circadian behavior GO:0048512 13 0.055
positive regulation of synaptic transmission glutamatergic GO:0051968 8 0.053
Mouse
catecholamine metabolic process GO:0006584 30 0.053
regulation of protein transport GO:0051223 163 0.053
Mouse
regulation of cytokine production GO:0001817 266 0.053
Mouse
glucose metabolic process GO:0006006 92 0.053
protein localization to organelle GO:0033365 185 0.052
Mouse
regulation of protein serine threonine kinase activity GO:0071900 157 0.052
positive regulation of cytosolic calcium ion concentration GO:0007204 65 0.052
Mouse
protein catabolic process GO:0030163 221 0.052
regulation of peptidyl tyrosine phosphorylation GO:0050730 93 0.052
Mouse
regulation of endothelial cell proliferation GO:0001936 23 0.052
Mouse
striated muscle tissue development GO:0014706 293 0.052
cell proliferation in hindbrain GO:0021534 10 0.051
regulation of corticotropin releasing hormone secretion GO:0043397 2 0.051
Mouse
positive regulation of protein phosphorylation GO:0001934 242 0.051
Mouse
regulation of cyclase activity GO:0031279 13 0.050
Mouse
regulation of neurotransmitter levels GO:0001505 87 0.050
neural precursor cell proliferation GO:0061351 121 0.050
smoothened signaling pathway GO:0007224 105 0.050
cellular carbohydrate metabolic process GO:0044262 119 0.050
Mouse
regulation of neurotransmitter transport GO:0051588 35 0.049
negative regulation of blood pressure GO:0045776 22 0.049
Mouse
regulation of bone mineralization GO:0030500 31 0.049
Mouse
regulation of cell cycle GO:0051726 281 0.049
digestive tract development GO:0048565 190 0.049
Mouse
response to corticosteroid GO:0031960 20 0.049
positive regulation of homeostatic process GO:0032846 64 0.048
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.048
glycosyl compound catabolic process GO:1901658 206 0.048
Mouse
regulation of lipid metabolic process GO:0019216 118 0.048
regulation of erk1 and erk2 cascade GO:0070372 71 0.048
positive regulation of secretion GO:0051047 130 0.048
Mouse
positive regulation of cytokine production GO:0001819 174 0.047
Mouse
cytokine secretion GO:0050663 72 0.047
Mouse
regulation of homeostatic process GO:0032844 182 0.046
regulation of heart rate GO:0002027 36 0.046
Mouse
purine ribonucleotide biosynthetic process GO:0009152 59 0.046
Mouse
sensory perception of light stimulus GO:0050953 54 0.046
nuclear import GO:0051170 95 0.046
Mouse
regulation of glial cell differentiation GO:0045685 41 0.045
bone remodeling GO:0046849 53 0.045
Mouse
positive regulation of map kinase activity GO:0043406 84 0.045
negative regulation of smooth muscle contraction GO:0045986 10 0.045
Mouse
neurotransmitter transport GO:0006836 76 0.044
positive regulation of cell motility GO:2000147 116 0.044
Mouse
response to drug GO:0042493 75 0.044
Mouse
regulation of circadian rhythm GO:0042752 58 0.044
positive regulation of camp biosynthetic process GO:0030819 19 0.043
Mouse
indole containing compound metabolic process GO:0042430 12 0.043
response to histamine GO:0034776 1 0.043
regulation of blood circulation GO:1903522 93 0.042
Mouse
regulation of cellular response to stress GO:0080135 159 0.042
nucleocytoplasmic transport GO:0006913 139 0.042
Mouse
cellular nitrogen compound catabolic process GO:0044270 280 0.042
Mouse
glucose import GO:0046323 32 0.042
Mouse
purine containing compound metabolic process GO:0072521 311 0.042
Mouse
regulation of adenylate cyclase activity GO:0045761 10 0.042
Mouse
multi organism behavior GO:0051705 62 0.041
Mouse
organic anion transport GO:0015711 137 0.041
purine nucleoside catabolic process GO:0006152 205 0.041
Mouse
generation of ovulation cycle rhythm GO:0060112 1 0.041
response to ethanol GO:0045471 18 0.041
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 61 0.041
Mouse
axon ensheathment GO:0008366 76 0.040
positive regulation of apoptotic process GO:0043065 217 0.040
positive regulation of mapk cascade GO:0043410 170 0.040
negative regulation of cell migration GO:0030336 59 0.040
apoptotic signaling pathway GO:0097190 306 0.040
leukocyte migration GO:0050900 124 0.040
neurotransmitter secretion GO:0007269 62 0.039
olfactory learning GO:0008355 2 0.039
negative regulation of camp biosynthetic process GO:0030818 5 0.039
Mouse
mitotic cell cycle GO:0000278 195 0.039
glycogen metabolic process GO:0005977 32 0.038
muscle tissue development GO:0060537 308 0.038
digestion GO:0007586 40 0.038
Mouse
ribonucleotide metabolic process GO:0009259 291 0.038
Mouse
regulation of interleukin 5 secretion GO:2000662 2 0.038
regulation of voltage gated calcium channel activity GO:1901385 4 0.038
regulation of nucleotide catabolic process GO:0030811 122 0.038
Mouse
protein secretion GO:0009306 111 0.037
Mouse
astrocyte differentiation GO:0048708 43 0.037
Mouse
lipid transport GO:0006869 98 0.037
negative regulation of dna replication GO:0008156 4 0.037
synaptic transmission glycinergic GO:0060012 2 0.037
epithelium migration GO:0090132 63 0.037
rhythmic behavior GO:0007622 15 0.036
regulation of peptide hormone secretion GO:0090276 75 0.036
Mouse
cellular polysaccharide metabolic process GO:0044264 38 0.036
renal system process GO:0003014 48 0.036
glucan metabolic process GO:0044042 32 0.036
potassium ion transport GO:0006813 52 0.036
hormone metabolic process GO:0042445 86 0.035
regulation of digestive system process GO:0044058 13 0.035
pallium development GO:0021543 120 0.035
Mouse
ribonucleotide biosynthetic process GO:0009260 59 0.035
Mouse
inner ear receptor cell differentiation GO:0060113 61 0.035
negative regulation of neuron differentiation GO:0045665 101 0.035
purine containing compound biosynthetic process GO:0072522 70 0.035
Mouse
protein kinase b signaling GO:0043491 74 0.035
substrate independent telencephalic tangential migration GO:0021826 8 0.035
Mouse
nerve development GO:0021675 67 0.035
adrenergic receptor signaling pathway GO:0071875 13 0.034
Mouse
cellular ion homeostasis GO:0006873 165 0.034
Mouse
forebrain neuron differentiation GO:0021879 52 0.034
Mouse
epithelial tube morphogenesis GO:0060562 303 0.034
second messenger mediated signaling GO:0019932 73 0.034
Mouse
cellular metal ion homeostasis GO:0006875 151 0.033
Mouse
positive regulation of cellular carbohydrate metabolic process GO:0010676 29 0.033
Mouse
carbohydrate transport GO:0008643 62 0.033
Mouse
regulation of heart contraction GO:0008016 77 0.033
Mouse
limbic system development GO:0021761 72 0.033
Mouse
negative regulation of potassium ion transport GO:0043267 7 0.033
primary amino compound metabolic process GO:1901160 8 0.033
ossification GO:0001503 216 0.032
Mouse
saliva secretion GO:0046541 6 0.032
regulation of protein secretion GO:0050708 82 0.032
Mouse
positive regulation of cellular amine metabolic process GO:0033240 5 0.032
protein autophosphorylation GO:0046777 61 0.032
synaptic transmission involved in micturition GO:0060084 3 0.032
endocytosis GO:0006897 168 0.031
Mouse
ribonucleoside triphosphate metabolic process GO:0009199 220 0.031
Mouse
response to glucocorticoid GO:0051384 20 0.031
phospholipid metabolic process GO:0006644 87 0.031
regulation of cell activation GO:0050865 289 0.031
positive regulation of cellular catabolic process GO:0031331 148 0.031
Mouse
negative regulation of systemic arterial blood pressure GO:0003085 15 0.031
Mouse
positive regulation of purine nucleotide biosynthetic process GO:1900373 26 0.030
Mouse
organic acid transport GO:0015849 101 0.030
response to organonitrogen compound GO:0010243 246 0.030
Mouse
regulation of appetite GO:0032098 12 0.030
Mouse
exocytosis GO:0006887 121 0.030
substantia nigra development GO:0021762 2 0.029
developmental maturation GO:0021700 193 0.029
negative regulation of muscle contraction GO:0045932 12 0.029
Mouse
regulation of norepinephrine secretion GO:0014061 2 0.029
monocarboxylic acid biosynthetic process GO:0072330 61 0.029
endocrine hormone secretion GO:0060986 15 0.029
oxidation reduction process GO:0055114 342 0.029
positive regulation of voltage gated calcium channel activity GO:1901387 2 0.029
regulation of potassium ion transport GO:0043266 16 0.029
biomineral tissue development GO:0031214 64 0.029
Mouse
cerebral cortex gabaergic interneuron migration GO:0021853 6 0.028
Mouse
body fluid secretion GO:0007589 53 0.028
ovulation cycle GO:0042698 59 0.028
regulation of reactive oxygen species metabolic process GO:2000377 40 0.028
energy derivation by oxidation of organic compounds GO:0015980 77 0.028
carbohydrate metabolic process GO:0005975 230 0.028
Mouse
calcium mediated signaling GO:0019722 46 0.028
regulation of ossification GO:0030278 112 0.028
Mouse
nucleoside phosphate metabolic process GO:0006753 338 0.027
Mouse
regulation of establishment of protein localization GO:0070201 181 0.027
Mouse
regulation of protein kinase b signaling GO:0051896 56 0.027
lipid biosynthetic process GO:0008610 179 0.027
regulation of anatomical structure size GO:0090066 178 0.027
Mouse
positive regulation of cyclic nucleotide metabolic process GO:0030801 24 0.027
Mouse
regulation of protein localization GO:0032880 231 0.027
Mouse
regulation of vesicle mediated transport GO:0060627 139 0.027
maintenance of location GO:0051235 89 0.027
negative regulation of nervous system development GO:0051961 156 0.026
regulation of smoothened signaling pathway GO:0008589 58 0.026
regulation of neuron death GO:1901214 134 0.026
cellular glucan metabolic process GO:0006073 32 0.026
negative regulation of cell development GO:0010721 169 0.026
lipid localization GO:0010876 126 0.026
regulation of the force of heart contraction GO:0002026 17 0.026
Mouse
cardiac chamber development GO:0003205 108 0.026
smooth muscle contraction GO:0006939 44 0.026
Mouse
detection of stimulus involved in sensory perception GO:0050906 44 0.026
positive regulation of growth hormone secretion GO:0060124 3 0.026
small gtpase mediated signal transduction GO:0007264 97 0.026
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.025
wnt signaling pathway GO:0016055 188 0.025
dicarboxylic acid transport GO:0006835 29 0.025
vasodilation GO:0042311 28 0.025
Mouse
detection of mechanical stimulus involved in sensory perception of pain GO:0050966 4 0.025
membrane organization GO:0061024 245 0.025
Rat
regulation of apoptotic signaling pathway GO:2001233 197 0.025
positive regulation of nervous system development GO:0051962 221 0.024
norepinephrine transport GO:0015874 2 0.024
peptidyl tyrosine modification GO:0018212 145 0.024
Mouse
regulation of long term neuronal synaptic plasticity GO:0048169 19 0.024
gamma aminobutyric acid signaling pathway GO:0007214 8 0.024
ras protein signal transduction GO:0007265 77 0.024
ear development GO:0043583 200 0.024
epithelial cell migration GO:0010631 63 0.024
regulation of mitotic cell cycle GO:0007346 126 0.024
polysaccharide metabolic process GO:0005976 39 0.024
positive regulation of stem cell proliferation GO:2000648 59 0.024
synaptic transmission gabaergic GO:0051932 19 0.024
regulation of cellular catabolic process GO:0031329 242 0.024
Mouse
negative regulation of adenylate cyclase activity GO:0007194 1 0.023
cellular response to histamine GO:0071420 1 0.023
regulation of purine nucleotide catabolic process GO:0033121 122 0.023
Mouse
inner ear receptor cell development GO:0060119 39 0.023
cytokine metabolic process GO:0042107 71 0.023
positive regulation of cell development GO:0010720 237 0.023
negative regulation of cell proliferation GO:0008285 296 0.023
regulation of blood vessel size GO:0050880 56 0.023
Mouse
central nervous system neuron differentiation GO:0021953 162 0.023
Mouse
neural nucleus development GO:0048857 22 0.023
establishment of glial blood brain barrier GO:0060857 2 0.022
telencephalon cell migration GO:0022029 55 0.022
Mouse
anatomical structure homeostasis GO:0060249 145 0.022
Mouse
regulation of transporter activity GO:0032409 57 0.022
regulation of cell adhesion GO:0030155 154 0.022
regulation of systemic arterial blood pressure by hormone GO:0001990 25 0.022
cell chemotaxis GO:0060326 81 0.022
osteoclast differentiation GO:0030316 62 0.022
positive regulation of programmed cell death GO:0043068 218 0.022

Htr1a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
central nervous system disease DOID:331 0 0.030
disease of anatomical entity DOID:7 0 0.030
Human
nervous system disease DOID:863 0 0.030