Mus musculus

161 known processes

Htr1b

5-hydroxytryptamine (serotonin) receptor 1B

Htr1b biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
nitrogen compound transport GO:0071705 271 0.611
purine containing compound metabolic process GO:0072521 311 0.400
gland development GO:0048732 330 0.374
Mouse
ribose phosphate biosynthetic process GO:0046390 59 0.303
small gtpase mediated signal transduction GO:0007264 97 0.292
purine nucleotide metabolic process GO:0006163 302 0.267
amine metabolic process GO:0009308 45 0.262
Mouse
stem cell differentiation GO:0048863 268 0.260
Mouse
negative regulation of protein metabolic process GO:0051248 282 0.253
central nervous system neuron development GO:0021954 67 0.245
Mouse
regulation of ion transport GO:0043269 215 0.240
regulation of cellular ketone metabolic process GO:0010565 66 0.231
regulation of cytokine production GO:0001817 266 0.230
Mouse
regulation of transferase activity GO:0051338 263 0.228
Mouse
carbohydrate derivative catabolic process GO:1901136 231 0.208
Mouse
monoamine transport GO:0015844 33 0.203
myeloid cell differentiation GO:0030099 233 0.201
adenylate cyclase inhibiting g protein coupled receptor signaling pathway GO:0007193 20 0.199
Human
forebrain development GO:0030900 302 0.198
Mouse
adenylate cyclase modulating g protein coupled receptor signaling pathway GO:0007188 54 0.196
Human Mouse
regulation of cellular catabolic process GO:0031329 242 0.192
Mouse
somatotropin secreting cell differentiation GO:0060126 4 0.191
ion transmembrane transport GO:0034220 361 0.189
ribose phosphate metabolic process GO:0019693 291 0.186
regulation of dopamine secretion GO:0014059 9 0.185
Rat
positive regulation of cell development GO:0010720 237 0.182
positive regulation of purine nucleotide biosynthetic process GO:1900373 26 0.172
Mouse
regulation of epithelial cell proliferation GO:0050678 141 0.168
Mouse
nucleoside phosphate metabolic process GO:0006753 338 0.166
leukocyte differentiation GO:0002521 342 0.161
cell division GO:0051301 120 0.160
Mouse
central nervous system neuron differentiation GO:0021953 162 0.159
Mouse
purine ribonucleotide metabolic process GO:0009150 290 0.159
associative learning GO:0008306 61 0.157
Mouse
heart morphogenesis GO:0003007 178 0.156
Mouse
ribonucleoside triphosphate metabolic process GO:0009199 220 0.152
Mouse
ribonucleoside catabolic process GO:0042454 206 0.152
Mouse
carbohydrate metabolic process GO:0005975 230 0.152
Mouse
anion transport GO:0006820 177 0.147
circulatory system process GO:0003013 197 0.147
Mouse
regulation of peptide hormone secretion GO:0090276 75 0.145
Mouse
response to light stimulus GO:0009416 135 0.140
Mouse
spermatogenesis GO:0007283 284 0.140
nucleotide biosynthetic process GO:0009165 78 0.140
nucleobase containing small molecule metabolic process GO:0055086 352 0.136
organonitrogen compound catabolic process GO:1901565 264 0.136
Mouse
protein catabolic process GO:0030163 221 0.133
positive regulation of programmed cell death GO:0043068 218 0.132
positive regulation of cellular catabolic process GO:0031331 148 0.132
Mouse
sensory perception GO:0007600 245 0.131
circadian rhythm GO:0007623 114 0.128
negative regulation of cell proliferation GO:0008285 296 0.128
regulation of secretion by cell GO:1903530 249 0.128
positive regulation of cyclic nucleotide metabolic process GO:0030801 24 0.128
Mouse
regulation of hormone levels GO:0010817 211 0.128
Mouse
peptide secretion GO:0002790 114 0.126
Mouse
dopamine metabolic process GO:0042417 23 0.125
Mouse
hypophysis morphogenesis GO:0048850 3 0.121
macromolecule catabolic process GO:0009057 281 0.118
purine ribonucleoside catabolic process GO:0046130 205 0.111
Mouse
cellular homeostasis GO:0019725 240 0.110
Mouse
ribonucleotide metabolic process GO:0009259 291 0.108
g protein coupled receptor signaling pathway GO:0007186 243 0.107
response to organonitrogen compound GO:0010243 246 0.106
Human Mouse Rat
catecholamine transport GO:0051937 21 0.105
Mouse Rat
guanosine containing compound catabolic process GO:1901069 144 0.103
Mouse
digestion GO:0007586 40 0.103
Mouse
limbic system development GO:0021761 72 0.102
Mouse
regulation of nucleotide metabolic process GO:0006140 169 0.101
nucleotide metabolic process GO:0009117 332 0.101
ras protein signal transduction GO:0007265 77 0.101
forebrain generation of neurons GO:0021872 63 0.101
Mouse
ribonucleoside metabolic process GO:0009119 245 0.100
Mouse
cellular response to organonitrogen compound GO:0071417 145 0.100
Human
regulation of catecholamine secretion GO:0050433 12 0.100
Rat
organic hydroxy compound biosynthetic process GO:1901617 77 0.097
renal inner medulla development GO:0072053 3 0.096
axonogenesis GO:0007409 274 0.095
camp metabolic process GO:0046058 40 0.095
response to organic cyclic compound GO:0014070 198 0.094
Mouse Rat
glycosyl compound metabolic process GO:1901657 246 0.094
Mouse
microtubule based process GO:0007017 236 0.094
cellular nitrogen compound catabolic process GO:0044270 280 0.094
Mouse
t cell differentiation in thymus GO:0033077 77 0.093
g protein coupled acetylcholine receptor signaling pathway GO:0007213 4 0.093
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.093
positive regulation of t cell apoptotic process GO:0070234 8 0.093
organonitrogen compound biosynthetic process GO:1901566 192 0.093
rhythmic process GO:0048511 174 0.093
visual behavior GO:0007632 45 0.092
Mouse
response to steroid hormone GO:0048545 56 0.091
Rat
generation of ovulation cycle rhythm GO:0060112 1 0.090
hindbrain formation GO:0021576 1 0.089
positive regulation of organelle organization GO:0010638 128 0.087
purine ribonucleotide biosynthetic process GO:0009152 59 0.086
regulation of cyclic nucleotide metabolic process GO:0030799 40 0.086
epithelial cell proliferation GO:0050673 174 0.082
Mouse
positive regulation of nucleotide catabolic process GO:0030813 88 0.081
Mouse
ribonucleoside triphosphate catabolic process GO:0009203 199 0.080
Mouse
regulation of lymphocyte activation GO:0051249 240 0.080
regulation of organelle organization GO:0033043 289 0.079
amino acid transport GO:0006865 61 0.079
neuronal action potential GO:0019228 54 0.079
Mouse
neuron death GO:0070997 154 0.078
purine nucleoside triphosphate catabolic process GO:0009146 203 0.078
Mouse
catecholamine metabolic process GO:0006584 30 0.077
Mouse
t cell activation GO:0042110 289 0.077
cyclic nucleotide biosynthetic process GO:0009190 44 0.077
cyclic purine nucleotide metabolic process GO:0052652 43 0.077
regulation of glutamate secretion GO:0014048 3 0.077
cellular chemical homeostasis GO:0055082 215 0.076
Mouse
synaptic transmission GO:0007268 329 0.076
Mouse Rat
multi multicellular organism process GO:0044706 109 0.076
Mouse
regulation of rna polymerase ii transcriptional preinitiation complex assembly GO:0045898 2 0.076
catecholamine secretion GO:0050432 15 0.075
Rat
formation of primary germ layer GO:0001704 77 0.075
response to nutrient levels GO:0031667 109 0.074
Mouse
gtp metabolic process GO:0046039 144 0.074
Mouse
positive regulation of cell death GO:0010942 224 0.074
inorganic cation transmembrane transport GO:0098662 207 0.073
aromatic compound catabolic process GO:0019439 286 0.073
Mouse
nucleotide catabolic process GO:0009166 217 0.073
Mouse
purine ribonucleoside metabolic process GO:0046128 241 0.072
Mouse
regulation of defense response GO:0031347 233 0.072
response to peptide GO:1901652 136 0.071
nucleoside metabolic process GO:0009116 246 0.071
Mouse
positive regulation of cytokine production GO:0001819 174 0.071
Mouse
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.071
Mouse
regulation of lyase activity GO:0051339 13 0.070
Mouse
regulation of cell activation GO:0050865 289 0.070
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.069
Mouse
peptide transport GO:0015833 133 0.069
Mouse
establishment of organ orientation GO:0048561 1 0.069
mesonephric duct formation GO:0072181 2 0.069
peptide hormone secretion GO:0030072 109 0.069
Mouse
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.068
gastrulation GO:0007369 116 0.068
positive regulation of camp metabolic process GO:0030816 19 0.067
Mouse
regulation of secretion GO:0051046 274 0.066
positive regulation of cell migration GO:0030335 109 0.066
Mouse
cellular ion homeostasis GO:0006873 165 0.066
Mouse
positive regulation of cyclic nucleotide biosynthetic process GO:0030804 24 0.066
Mouse
learning GO:0007612 98 0.065
Mouse
carbohydrate derivative biosynthetic process GO:1901137 183 0.065
negative regulation of secretion GO:0051048 61 0.064
positive regulation of fat cell differentiation GO:0045600 32 0.063
Mouse
organic acid transport GO:0015849 101 0.063
regulation of cellular component size GO:0032535 121 0.063
cytokine production GO:0001816 319 0.062
Mouse
locomotory behavior GO:0007626 195 0.062
Mouse
hepaticobiliary system development GO:0061008 67 0.062
regulation of neurotransmitter levels GO:0001505 87 0.062
regulation of circadian rhythm GO:0042752 58 0.062
paraxial mesodermal cell differentiation GO:0048342 2 0.061
nuclear transport GO:0051169 139 0.060
Mouse
response to radiation GO:0009314 165 0.060
Mouse
cranial nerve development GO:0021545 41 0.059
spemann organizer formation GO:0060061 2 0.059
phospholipase c activating g protein coupled receptor signaling pathway GO:0007200 26 0.059
Mouse
nephric duct formation GO:0072179 4 0.059
positive regulation of apoptotic process GO:0043065 217 0.059
neurotransmitter transport GO:0006836 76 0.058
homeostasis of number of cells GO:0048872 210 0.058
heterocycle catabolic process GO:0046700 280 0.058
Mouse
positive regulation of protein phosphorylation GO:0001934 242 0.057
Mouse
organophosphate catabolic process GO:0046434 232 0.057
Mouse
norepinephrine transport GO:0015874 2 0.057
negative regulation of synapse assembly GO:0051964 3 0.057
glycosyl compound catabolic process GO:1901658 206 0.056
Mouse
morphogenesis of a branching structure GO:0001763 203 0.056
positive regulation of nucleotide metabolic process GO:0045981 114 0.056
Mouse
gtp catabolic process GO:0006184 143 0.055
Mouse
regulation of peptide transport GO:0090087 91 0.055
Mouse
sensory perception of light stimulus GO:0050953 54 0.054
organophosphate biosynthetic process GO:0090407 122 0.054
heart process GO:0003015 94 0.053
Mouse
mesoderm development GO:0007498 100 0.053
regulation of protein catabolic process GO:0042176 108 0.052
organic hydroxy compound transport GO:0015850 93 0.052
actin cytoskeleton organization GO:0030036 220 0.052
regulation of leukocyte differentiation GO:1902105 159 0.052
lateral sprouting involved in mammary gland duct morphogenesis GO:0060599 2 0.052
positive regulation of growth GO:0045927 104 0.052
regulation of membrane potential GO:0042391 192 0.051
Mouse
negative regulation of epithelial cell proliferation GO:0050680 64 0.051
regulation of inflammatory response GO:0050727 147 0.051
purine nucleoside catabolic process GO:0006152 205 0.051
Mouse
urogenital system development GO:0001655 261 0.051
multicellular organismal signaling GO:0035637 91 0.050
Mouse
cell adhesion GO:0007155 329 0.050
peptidyl amino acid modification GO:0018193 336 0.050
Mouse
male gamete generation GO:0048232 285 0.050
ribonucleotide biosynthetic process GO:0009260 59 0.049
regulation of ossification GO:0030278 112 0.048
Mouse
guanosine containing compound metabolic process GO:1901068 144 0.048
Mouse
brain morphogenesis GO:0048854 32 0.048
negative regulation of cell motility GO:2000146 61 0.048
regulation of leukocyte proliferation GO:0070663 121 0.048
regulation of canonical wnt signaling pathway involved in controlling type b pancreatic cell proliferation GO:2000079 1 0.047
regulation of purine nucleotide metabolic process GO:1900542 169 0.047
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.046
cellular ketone metabolic process GO:0042180 84 0.046
cation homeostasis GO:0055080 212 0.046
Mouse
cell matrix adhesion GO:0007160 68 0.046
multicellular organism growth GO:0035264 161 0.046
Mouse
regulation of response to wounding GO:1903034 189 0.046
myeloid cell homeostasis GO:0002262 114 0.045
regulation of cellular amino acid metabolic process GO:0006521 5 0.045
cation transmembrane transport GO:0098655 266 0.045
hormone secretion GO:0046879 128 0.045
Mouse
cell type specific apoptotic process GO:0097285 268 0.045
canonical wnt signaling pathway involved in regulation of type b pancreatic cell proliferation GO:0044343 1 0.045
nucleoside phosphate biosynthetic process GO:1901293 79 0.044
wound healing GO:0042060 157 0.044
t cell differentiation GO:0030217 174 0.044
regulation of neuron projection development GO:0010975 169 0.044
g1 s transition of mitotic cell cycle GO:0000082 57 0.044
metanephric loop of henle development GO:0072236 4 0.044
superior vena cava morphogenesis GO:0060578 1 0.044
establishment of endothelial blood brain barrier GO:0014045 3 0.043
regulation of carbohydrate metabolic process GO:0006109 75 0.043
Mouse
renal vesicle induction GO:0072034 3 0.043
negative regulation of prostatic bud formation GO:0060686 4 0.043
regulation of lymphocyte proliferation GO:0050670 117 0.043
purine nucleotide biosynthetic process GO:0006164 65 0.043
regulation of protein transport GO:0051223 163 0.043
Mouse
positive regulation of interleukin 8 secretion GO:2000484 1 0.043
regulation of purine nucleotide catabolic process GO:0033121 122 0.043
Mouse
ameboidal type cell migration GO:0001667 128 0.043
Mouse
regulation of kinase activity GO:0043549 249 0.043
Mouse
amide transport GO:0042886 138 0.042
Mouse
calcium mediated signaling GO:0019722 46 0.042
lymphocyte proliferation GO:0046651 164 0.042
lymphocyte differentiation GO:0030098 242 0.042
blood vessel morphogenesis GO:0048514 285 0.042
Mouse
positive regulation of hydrolase activity GO:0051345 148 0.042
Mouse
optic nerve development GO:0021554 8 0.042
mesenchyme development GO:0060485 152 0.042
Mouse
regulation of reproductive process GO:2000241 66 0.041
regulation of asymmetric cell division GO:0009786 4 0.041
body fluid secretion GO:0007589 53 0.041
outer medullary collecting duct development GO:0072060 1 0.041
maintenance of cell number GO:0098727 3 0.041
lung induction GO:0060492 3 0.040
regulation of testosterone biosynthetic process GO:2000224 2 0.040
regulation of hormone secretion GO:0046883 88 0.040
Mouse
paraxial mesodermal cell fate commitment GO:0048343 2 0.040
leukocyte proliferation GO:0070661 172 0.040
epithelial cell development GO:0002064 159 0.040
Mouse
negative regulation of immune system process GO:0002683 209 0.040
spemann organizer formation at the anterior end of the primitive streak GO:0060064 1 0.039
cerebellum formation GO:0021588 1 0.039
insulin secretion GO:0030073 89 0.039
neuroblast differentiation GO:0014016 2 0.039
negative regulation of adenylate cyclase activity GO:0007194 1 0.039
sensory perception of chemical stimulus GO:0007606 51 0.039
astrocyte differentiation GO:0048708 43 0.039
Mouse
regulation of neuron differentiation GO:0045664 281 0.039
somatostatin receptor signaling pathway GO:0038169 2 0.039
adenylate cyclase inhibiting serotonin receptor signaling pathway GO:0007198 1 0.038
Human
stem cell development GO:0048864 219 0.038
Mouse
cellular response to hormone stimulus GO:0032870 150 0.038
regulation of b cell activation GO:0050864 81 0.038
central nervous system morphogenesis GO:0021551 2 0.037
regulation of body fluid levels GO:0050878 162 0.037
nephron morphogenesis GO:0072028 69 0.037
regulation of saliva secretion GO:0046877 2 0.036
regulation of anion transport GO:0044070 27 0.036
regulation of protein localization GO:0032880 231 0.036
Mouse
conditioned taste aversion GO:0001661 4 0.036
Mouse
carbon catabolite repression of transcription from rna polymerase ii promoter GO:0000437 1 0.036
negative regulation of testosterone biosynthetic process GO:2000225 1 0.036
ossification GO:0001503 216 0.036
Mouse
tendon cell differentiation GO:0035990 4 0.035
cyclic nucleotide metabolic process GO:0009187 59 0.035
lung field specification GO:0060424 3 0.035
cellular protein catabolic process GO:0044257 155 0.035
cell growth GO:0016049 130 0.035
regulation of protein processing GO:0070613 96 0.035
rho protein signal transduction GO:0007266 32 0.035
transmembrane transport GO:0055085 412 0.035
astrocyte development GO:0014002 12 0.035
Mouse
regulation of anagen GO:0051884 1 0.035
positive regulation of homeostatic process GO:0032846 64 0.035
positive regulation of protein transport GO:0051222 93 0.035
Mouse
oxygen homeostasis GO:0032364 2 0.035
positive regulation of renal sodium excretion GO:0035815 2 0.034
non canonical wnt signaling pathway via jnk cascade GO:0038031 3 0.034
regulation of feeding behavior GO:0060259 3 0.034
membrane organization GO:0061024 245 0.034
blood circulation GO:0008015 195 0.034
Mouse
regulation of cell migration GO:0030334 219 0.034
Mouse
positive regulation of cell activation GO:0050867 158 0.033
epithelial cell migration GO:0010631 63 0.033
modification dependent protein catabolic process GO:0019941 133 0.033
positive regulation of catecholamine secretion GO:0033605 2 0.033
glial cell differentiation GO:0010001 131 0.033
Mouse
regulation of cell division GO:0051302 76 0.033
Mouse
establishment of planar polarity involved in nephron morphogenesis GO:0072046 1 0.033
central nervous system vasculogenesis GO:0022009 3 0.033
lipid localization GO:0010876 126 0.033
regionalization GO:0003002 337 0.033
positive regulation of camp biosynthetic process GO:0030819 19 0.033
Mouse
regulation of mapk cascade GO:0043408 248 0.033
positive regulation of cytoskeleton organization GO:0051495 49 0.033
embryonic organ morphogenesis GO:0048562 276 0.032
purine containing compound biosynthetic process GO:0072522 70 0.032
epithelium migration GO:0090132 63 0.032
kidney rudiment formation GO:0072003 3 0.032
mitochondrion organization GO:0007005 134 0.032
protein maturation GO:0051604 176 0.032
modification dependent macromolecule catabolic process GO:0043632 133 0.032
cellular carbohydrate metabolic process GO:0044262 119 0.032
Mouse
negative regulation of protein modification process GO:0031400 163 0.032
spermatid differentiation GO:0048515 115 0.032
multicellular organismal homeostasis GO:0048871 164 0.032
Mouse
b cell proliferation GO:0042100 53 0.032
midbrain hindbrain boundary maturation during brain development GO:0022004 1 0.032
regulation of fat cell differentiation GO:0045598 81 0.031
Mouse
postganglionic parasympathetic nervous system development GO:0021784 2 0.031
anagen GO:0042640 13 0.031
liver development GO:0001889 66 0.031
regulation of ketone biosynthetic process GO:0010566 2 0.031
developmental cell growth GO:0048588 84 0.031
protein processing GO:0016485 163 0.031
protein localization to nucleus GO:0034504 121 0.030
Mouse
gabaergic neuron differentiation GO:0097154 11 0.030
Mouse
protein localization to organelle GO:0033365 185 0.030
Mouse
olfactory bulb interneuron differentiation GO:0021889 12 0.030
regulation of axon diameter GO:0031133 6 0.030
forebrain neuron development GO:0021884 30 0.030
Mouse
establishment or maintenance of polarity of embryonic epithelium GO:0016332 1 0.030
positive regulation of cell cycle process GO:0090068 61 0.030
spinal cord oligodendrocyte cell fate specification GO:0021530 3 0.030
endocytosis GO:0006897 168 0.030
regulation of anatomical structure size GO:0090066 178 0.030
Mouse
tissue migration GO:0090130 68 0.030
protein targeting GO:0006605 143 0.030
Mouse
regulation of cellular carbohydrate metabolic process GO:0010675 75 0.030
Mouse
regulation of peptide secretion GO:0002791 77 0.030
Mouse
apoptotic signaling pathway GO:0097190 306 0.030
activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 3 0.030
transforming growth factor beta2 production GO:0032906 2 0.029
positive regulation of cell morphogenesis involved in differentiation GO:0010770 72 0.029
regulation of norepinephrine secretion GO:0014061 2 0.029
action potential GO:0001508 78 0.029
Mouse
regulation of hydrolase activity GO:0051336 246 0.028
Mouse
nerve development GO:0021675 67 0.028
cellular response to abiotic stimulus GO:0071214 56 0.028
response to peptide hormone GO:0043434 127 0.028
ubiquitin dependent protein catabolic process GO:0006511 129 0.028
positive regulation of leukocyte differentiation GO:1902107 86 0.028
tertiary branching involved in mammary gland duct morphogenesis GO:0060748 3 0.028
regulation of cell motility GO:2000145 236 0.028
Mouse
purine ribonucleotide catabolic process GO:0009154 208 0.028
Mouse
midbrain hindbrain boundary maturation GO:0021732 1 0.028
nucleoside triphosphate catabolic process GO:0009143 205 0.028
Mouse
cellular macromolecule catabolic process GO:0044265 206 0.028
glial cell development GO:0021782 54 0.028
Mouse
regulation of cytoskeleton organization GO:0051493 122 0.027
rna polymerase ii transcriptional preinitiation complex assembly GO:0051123 3 0.027
regulation of cellular amine metabolic process GO:0033238 20 0.027
Mouse
response to growth factor GO:0070848 198 0.027
endothelial cell differentiation GO:0045446 41 0.027
learning or memory GO:0007611 148 0.027
Mouse
monosaccharide metabolic process GO:0005996 106 0.027
positive regulation of interleukin 8 production GO:0032757 2 0.027
lens development in camera type eye GO:0002088 62 0.027
regulation of map kinase activity GO:0043405 120 0.027
cop9 signalosome assembly GO:0010387 2 0.027
dicarboxylic acid transport GO:0006835 29 0.027
protein import into nucleus GO:0006606 95 0.027
Mouse
platelet activation GO:0030168 40 0.026
regulation of purine nucleotide biosynthetic process GO:1900371 34 0.026
branching involved in ureteric bud morphogenesis GO:0001658 56 0.026
germ cell development GO:0007281 185 0.026
regulation of ras protein signal transduction GO:0046578 114 0.026
Mouse
kidney morphogenesis GO:0060993 83 0.026
pons maturation GO:0021586 3 0.026
mesoderm formation GO:0001707 62 0.026
establishment of anatomical structure orientation GO:0048560 1 0.026
androgen biosynthetic process GO:0006702 4 0.026
cellular response to parathyroid hormone stimulus GO:0071374 2 0.026
digestive system development GO:0055123 200 0.026
Mouse
regulation of transforming growth factor beta2 production GO:0032909 2 0.026
regulation of lymphocyte differentiation GO:0045619 107 0.026
establishment or maintenance of cell polarity GO:0007163 86 0.026
telencephalon development GO:0021537 186 0.026
Mouse
positive regulation of cell cycle GO:0045787 92 0.026
response to ketone GO:1901654 15 0.025
positive regulation of canonical wnt signaling pathway involved in controlling type b pancreatic cell proliferation GO:2000081 1 0.025
norepinephrine secretion GO:0048243 2 0.025
negative regulation of protein catabolic process GO:0042177 36 0.025
positive regulation of neuron differentiation GO:0045666 141 0.025
corpora quadrigemina development GO:0061378 2 0.025
ubiquitin dependent smad protein catabolic process GO:0030579 2 0.025
regulation of interleukin 6 production GO:0032675 55 0.025
cellular response to external stimulus GO:0071496 88 0.025
skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration GO:0014834 3 0.024
positive regulation of dopamine secretion GO:0033603 2 0.024
purine nucleotide catabolic process GO:0006195 211 0.024
Mouse
hematopoietic progenitor cell differentiation GO:0002244 143 0.024
nephron tubule formation GO:0072079 20 0.024
testosterone biosynthetic process GO:0061370 2 0.024
positive regulation of rna polymerase ii transcriptional preinitiation complex assembly GO:0045899 2 0.024
ribonucleotide catabolic process GO:0009261 208 0.024
Mouse
operant conditioning GO:0035106 2 0.024
Mouse
b cell activation GO:0042113 161 0.024
blood coagulation GO:0007596 76 0.024
meiotic nuclear division GO:0007126 115 0.024
tube formation GO:0035148 140 0.024
regulation of protein serine threonine kinase activity GO:0071900 157 0.024
intracellular protein transport GO:0006886 204 0.024
Mouse
purine containing compound catabolic process GO:0072523 213 0.024
Mouse
negative regulation of androgen biosynthetic process GO:2000180 1 0.023
hormone metabolic process GO:0042445 86 0.023
regulation of chromatin modification GO:1903308 57 0.023
erythrocyte differentiation GO:0030218 88 0.023
positive regulation of purine nucleotide catabolic process GO:0033123 88 0.023
Mouse
organic cyclic compound catabolic process GO:1901361 295 0.023
Mouse
positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis GO:0072108 3 0.023
epidermis development GO:0008544 187 0.023
negative regulation of cell development GO:0010721 169 0.023
positive regulation of nervous system development GO:0051962 221 0.023
canonical wnt signaling pathway involved in regulation of cell proliferation GO:0044340 3 0.023
cytoplasmic transport GO:0016482 234 0.023
Mouse
neuroblast fate determination GO:0007400 1 0.023
fat cell differentiation GO:0045444 160 0.023
Mouse
nucleoside phosphate catabolic process GO:1901292 222 0.022
Mouse
non canonical wnt signaling pathway via mapk cascade GO:0038030 3 0.022
wnt signaling pathway involved in forebrain neuroblast division GO:0021874 2 0.022
regulation of transmembrane transport GO:0034762 128 0.022
regulation of cyclic nucleotide biosynthetic process GO:0030802 31 0.022
positive regulation of leukocyte proliferation GO:0070665 73 0.022
positive regulation of adenylate cyclase activity involved in g protein coupled receptor signaling pathway GO:0010579 3 0.022
circadian sleep wake cycle rem sleep GO:0042747 1 0.022
microtubule cytoskeleton organization GO:0000226 157 0.022
positive regulation of branching involved in ureteric bud morphogenesis GO:0090190 18 0.022
response to alkaloid GO:0043279 34 0.022
Human Mouse Rat
protein kinase c activating g protein coupled receptor signaling pathway GO:0007205 4 0.022
response to extracellular stimulus GO:0009991 127 0.022
Mouse
planar cell polarity pathway involved in pericardium morphogenesis GO:0061354 2 0.022
cellular divalent inorganic cation homeostasis GO:0072503 127 0.022
Mouse
negative regulation of neuron differentiation GO:0045665 101 0.022
cellular response to lipid GO:0071396 145 0.022
regulation of rho protein signal transduction GO:0035023 71 0.022
foregut regionalization GO:0060423 3 0.022
regulation of nucleotide catabolic process GO:0030811 122 0.022
Mouse
response to testosterone GO:0033574 3 0.022
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.022
synaptic transmission involved in micturition GO:0060084 3 0.022
negative regulation of cellular component organization GO:0051129 194 0.022
regulation of meiotic cell cycle GO:0051445 34 0.022
negative regulation of purine nucleotide metabolic process GO:1900543 16 0.021
energy derivation by oxidation of organic compounds GO:0015980 77 0.021
regulation of ras gtpase activity GO:0032318 88 0.021
Mouse
positive regulation of ion transport GO:0043270 65 0.021
inorganic anion transport GO:0015698 43 0.021
cognition GO:0050890 149 0.021
Mouse
tissue remodeling GO:0048771 102 0.021
generation of precursor metabolites and energy GO:0006091 103 0.021
Mouse
general adaptation syndrome GO:0051866 2 0.021
positive regulation of cyclase activity GO:0031281 11 0.021
Mouse
positive regulation of meiotic cell cycle GO:0051446 15 0.021
feeding behavior GO:0007631 62 0.021
Mouse Rat
visual learning GO:0008542 44 0.021
Mouse
negative regulation of phosphate metabolic process GO:0045936 184 0.021
cellular response to insulin stimulus GO:0032869 78 0.021
mapk cascade GO:0000165 281 0.021
Mouse
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.021
type b pancreatic cell proliferation GO:0044342 10 0.021
optic nerve structural organization GO:0021633 2 0.021
habituation GO:0046959 3 0.020
Mouse
alcohol metabolic process GO:0006066 116 0.020
digestive tract morphogenesis GO:0048546 147 0.020
tachykinin receptor signaling pathway GO:0007217 1 0.020
regulation of vasculature development GO:1901342 88 0.020
endothelium development GO:0003158 45 0.020
neuropeptide signaling pathway GO:0007218 19 0.020
positive regulation of epithelial cell proliferation involved in lung morphogenesis GO:0060501 3 0.020
camp biosynthetic process GO:0006171 31 0.020
neuron migration GO:0001764 122 0.020
Mouse
regulation of ion transmembrane transport GO:0034765 119 0.020
digestive tract development GO:0048565 190 0.020
Mouse
t cell apoptotic process GO:0070231 39 0.020
regulation of blood pressure GO:0008217 93 0.020
Mouse
central nervous system projection neuron axonogenesis GO:0021952 21 0.020
transition metal ion homeostasis GO:0055076 54 0.020
oocyte differentiation GO:0009994 35 0.020
regulation of myeloid leukocyte differentiation GO:0002761 58 0.020
branching morphogenesis of an epithelial tube GO:0048754 159 0.020

Htr1b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
bone disease DOID:0080001 0 0.026
disease of anatomical entity DOID:7 0 0.026
musculoskeletal system disease DOID:17 0 0.026
connective tissue disease DOID:65 0 0.026