Mus musculus

13 known processes

H2-T10

histocompatibility 2, T region locus 10

(Aliases: H-2T10)

H2-T10 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
positive regulation of t cell mediated cytotoxicity GO:0001916 15 0.242
Mouse
regulation of cytokine production GO:0001817 266 0.070
Mouse
regulation of defense response GO:0031347 233 0.065
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.065
Mouse
innate immune response GO:0045087 157 0.065
lymphocyte mediated immunity GO:0002449 139 0.062
Mouse
reactive nitrogen species metabolic process GO:2001057 0 0.057
t cell activation GO:0042110 289 0.052
regulation of cellular amine metabolic process GO:0033238 20 0.051
immune effector process GO:0002252 321 0.051
Mouse
defense response to other organism GO:0098542 197 0.048
Mouse
cytokine production GO:0001816 319 0.046
Mouse
regulation of cellular ketone metabolic process GO:0010565 66 0.046
regulation of cellular amino acid metabolic process GO:0006521 5 0.045
organic cyclic compound catabolic process GO:1901361 295 0.044
reactive oxygen species biosynthetic process GO:1903409 8 0.043
amine metabolic process GO:0009308 45 0.043
cellular ketone metabolic process GO:0042180 84 0.043
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.042
cellular amine metabolic process GO:0044106 44 0.042
response to molecule of bacterial origin GO:0002237 143 0.042
cellular amino acid metabolic process GO:0006520 103 0.041
regulation of reactive oxygen species metabolic process GO:2000377 40 0.040
carbohydrate derivative catabolic process GO:1901136 231 0.039
reactive oxygen species metabolic process GO:0072593 84 0.038
regulation of leukocyte mediated cytotoxicity GO:0001910 38 0.038
Mouse
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.037
positive regulation of cellular amine metabolic process GO:0033240 5 0.037
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 61 0.036
Mouse
negative regulation of protein metabolic process GO:0051248 282 0.036
positive regulation of cytokine production GO:0001819 174 0.036
Mouse
leukocyte mediated cytotoxicity GO:0001909 62 0.036
Mouse
negative regulation of cell proliferation GO:0008285 296 0.035
cellular response to cytokine stimulus GO:0071345 189 0.035
leukocyte activation involved in immune response GO:0002366 126 0.035
positive regulation of interferon gamma production GO:0032729 39 0.033
Mouse
regulation of interferon gamma production GO:0032649 57 0.032
Mouse
defense response to bacterium GO:0042742 119 0.032
aromatic compound catabolic process GO:0019439 286 0.032
cation transport GO:0006812 399 0.031
positive regulation of adaptive immune response GO:0002821 61 0.031
Mouse
cellular nitrogen compound catabolic process GO:0044270 280 0.031
negative regulation of cellular protein metabolic process GO:0032269 247 0.031
nucleobase containing small molecule metabolic process GO:0055086 352 0.030
nucleoside triphosphate metabolic process GO:0009141 230 0.030
regulation of cell activation GO:0050865 289 0.029
regulation of lymphocyte activation GO:0051249 240 0.029
nucleoside phosphate metabolic process GO:0006753 338 0.029
regulation of cell killing GO:0031341 40 0.029
Mouse
intracellular protein transport GO:0006886 204 0.029
purine containing compound catabolic process GO:0072523 213 0.029
lymphocyte activation involved in immune response GO:0002285 93 0.028
nucleoside triphosphate catabolic process GO:0009143 205 0.028
purine nucleoside metabolic process GO:0042278 241 0.028
purine nucleotide metabolic process GO:0006163 302 0.028
response to lipopolysaccharide GO:0032496 128 0.027
response to organic cyclic compound GO:0014070 198 0.027
regulation of lymphocyte mediated immunity GO:0002706 84 0.027
Mouse
regulation of secretion by cell GO:1903530 249 0.027
regulation of hydrolase activity GO:0051336 246 0.026
leukocyte mediated immunity GO:0002443 174 0.026
Mouse
protein modification by small protein conjugation or removal GO:0070647 207 0.026
organonitrogen compound catabolic process GO:1901565 264 0.026
negative regulation of phosphate metabolic process GO:0045936 184 0.025
sequestering of metal ion GO:0051238 19 0.025
regulation of adaptive immune response GO:0002819 90 0.025
Mouse
oxidation reduction process GO:0055114 342 0.025
nucleotide catabolic process GO:0009166 217 0.025
cell killing GO:0001906 67 0.025
Mouse
purine ribonucleoside metabolic process GO:0046128 241 0.025
negative regulation of immune system process GO:0002683 209 0.025
cation homeostasis GO:0055080 212 0.024
cell adhesion GO:0007155 329 0.024
ribose phosphate metabolic process GO:0019693 291 0.024
negative regulation of phosphorus metabolic process GO:0010563 184 0.024
positive regulation of leukocyte mediated immunity GO:0002705 70 0.024
Mouse
protein maturation GO:0051604 176 0.024
purine ribonucleotide catabolic process GO:0009154 208 0.024
positive regulation of immune effector process GO:0002699 107 0.023
Mouse
positive regulation of protein modification process GO:0031401 299 0.023
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.023
nucleotide metabolic process GO:0009117 332 0.023
antigen processing and presentation of endogenous peptide antigen via mhc class i via er pathway GO:0002484 3 0.023
protein processing GO:0016485 163 0.023
ribonucleoside metabolic process GO:0009119 245 0.023
inflammatory response GO:0006954 244 0.023
negative regulation of phosphorylation GO:0042326 166 0.023
negative regulation of defense response GO:0031348 77 0.023
heterocycle catabolic process GO:0046700 280 0.022
regulation of protein localization GO:0032880 231 0.022
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.022
positive regulation of defense response GO:0031349 124 0.022
production of molecular mediator of immune response GO:0002440 103 0.022
nucleoside metabolic process GO:0009116 246 0.022
purine ribonucleotide metabolic process GO:0009150 290 0.022
cell type specific apoptotic process GO:0097285 268 0.022
multicellular organismal homeostasis GO:0048871 164 0.022
negative regulation of protein phosphorylation GO:0001933 126 0.022
positive regulation of cell killing GO:0031343 33 0.022
Mouse
t cell proliferation GO:0042098 120 0.022
negative regulation of molecular function GO:0044092 258 0.022
regulation of t cell mediated cytotoxicity GO:0001914 18 0.022
Mouse
regulation of cellular catabolic process GO:0031329 242 0.022
adaptive immune response GO:0002250 155 0.022
Mouse
lymphocyte proliferation GO:0046651 164 0.021
lymphocyte differentiation GO:0030098 242 0.021
positive regulation of reactive oxygen species metabolic process GO:2000379 11 0.021
cellular macromolecule catabolic process GO:0044265 206 0.021
regulation of leukocyte mediated immunity GO:0002703 104 0.021
Mouse
apoptotic signaling pathway GO:0097190 306 0.021
sequestering of calcium ion GO:0051208 18 0.021
regulation of cell motility GO:2000145 236 0.021
regulation of response to wounding GO:1903034 189 0.021
ribonucleotide metabolic process GO:0009259 291 0.021
purine nucleoside catabolic process GO:0006152 205 0.020
leukocyte differentiation GO:0002521 342 0.020
regulation of membrane potential GO:0042391 192 0.020
response to organonitrogen compound GO:0010243 246 0.020
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 87 0.020
Mouse
macromolecule catabolic process GO:0009057 281 0.020
regulation of hormone levels GO:0010817 211 0.020
metal ion homeostasis GO:0055065 189 0.020
cellular lipid metabolic process GO:0044255 323 0.020
iron ion import into cell GO:0097459 4 0.020
positive regulation of innate immune response GO:0045089 80 0.019
purine ribonucleoside catabolic process GO:0046130 205 0.019
negative regulation of protein modification process GO:0031400 163 0.019
glycosyl compound metabolic process GO:1901657 246 0.019
g protein coupled receptor signaling pathway GO:0007186 243 0.019
cell activation involved in immune response GO:0002263 126 0.019
antigen processing and presentation GO:0019882 47 0.019
Mouse
peptidyl amino acid modification GO:0018193 336 0.019
synaptic transmission GO:0007268 329 0.019
organophosphate catabolic process GO:0046434 232 0.019
cellular chemical homeostasis GO:0055082 215 0.018
regulation of establishment of protein localization GO:0070201 181 0.018
regulation of t cell mediated immunity GO:0002709 34 0.018
Mouse
cellular homeostasis GO:0019725 240 0.018
cytoplasmic transport GO:0016482 234 0.018
negative regulation of cellular amine metabolic process GO:0033239 1 0.018
leukocyte proliferation GO:0070661 172 0.018
ear development GO:0043583 200 0.018
germ cell development GO:0007281 185 0.018
regulation of secretion GO:0051046 274 0.018
t cell mediated cytotoxicity GO:0001913 26 0.018
Mouse
blood vessel morphogenesis GO:0048514 285 0.018
hematopoietic progenitor cell differentiation GO:0002244 143 0.018
purine nucleoside triphosphate catabolic process GO:0009146 203 0.018
male gamete generation GO:0048232 285 0.018
divalent inorganic cation transport GO:0072511 178 0.018
spermatogenesis GO:0007283 284 0.018
epithelial tube morphogenesis GO:0060562 303 0.018
nucleoside catabolic process GO:0009164 206 0.018
cellular response to lipid GO:0071396 145 0.018
positive regulation of secretion GO:0051047 130 0.017
positive regulation of leukocyte mediated cytotoxicity GO:0001912 31 0.017
Mouse
activation of immune response GO:0002253 138 0.017
protein catabolic process GO:0030163 221 0.017
protein modification by small protein conjugation GO:0032446 187 0.017
purine nucleoside triphosphate metabolic process GO:0009144 226 0.017
sensory perception GO:0007600 245 0.017
ribonucleoside triphosphate metabolic process GO:0009199 220 0.017
purine containing compound metabolic process GO:0072521 311 0.017
angiogenesis GO:0001525 201 0.017
respiratory system development GO:0060541 190 0.017
positive regulation of lymphocyte mediated immunity GO:0002708 62 0.017
Mouse
organic hydroxy compound metabolic process GO:1901615 203 0.017
skin development GO:0043588 220 0.017
alpha beta t cell activation GO:0046631 91 0.017
negative regulation of intracellular signal transduction GO:1902532 167 0.017
regulation of t cell activation GO:0050863 170 0.017
ion transmembrane transport GO:0034220 361 0.017
regulation of homeostatic process GO:0032844 182 0.016
response to protozoan GO:0001562 28 0.016
regulation of proteolysis GO:0030162 164 0.016
gtp catabolic process GO:0006184 143 0.016
regulation of peptidase activity GO:0052547 96 0.016
regulation of inflammatory response GO:0050727 147 0.016
regulation of endopeptidase activity GO:0052548 89 0.016
ossification GO:0001503 216 0.016
regulation of cell cycle GO:0051726 281 0.016
cellular response to molecule of bacterial origin GO:0071219 83 0.016
t cell mediated immunity GO:0002456 50 0.016
Mouse
regulation of protein transport GO:0051223 163 0.016
nitrogen compound transport GO:0071705 271 0.016
protein ubiquitination GO:0016567 171 0.016
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.016
nucleoside phosphate catabolic process GO:1901292 222 0.016
antigen processing and presentation of endogenous peptide antigen via mhc class ib GO:0002476 4 0.016
Mouse
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.015
positive regulation of hydrolase activity GO:0051345 148 0.015
small gtpase mediated signal transduction GO:0007264 97 0.015
transmembrane transport GO:0055085 412 0.015
cellular metal ion homeostasis GO:0006875 151 0.015
regulation of neuron differentiation GO:0045664 281 0.015
ribonucleoside catabolic process GO:0042454 206 0.015
endomembrane system organization GO:0010256 147 0.015
ribonucleoside triphosphate catabolic process GO:0009203 199 0.015
positive regulation of secretion by cell GO:1903532 114 0.015
positive regulation of proteolysis GO:0045862 85 0.015
regulation of nucleotide metabolic process GO:0006140 169 0.015
purine nucleotide catabolic process GO:0006195 211 0.015
cellular response to biotic stimulus GO:0071216 92 0.015
compound eye development GO:0048749 1 0.015
homeostasis of number of cells GO:0048872 210 0.015
defense response to virus GO:0051607 68 0.015
Mouse
positive regulation of nervous system development GO:0051962 221 0.015
myeloid cell differentiation GO:0030099 233 0.015
glucose homeostasis GO:0042593 128 0.014
ribonucleotide catabolic process GO:0009261 208 0.014
dna metabolic process GO:0006259 303 0.014
maintenance of location GO:0051235 89 0.014
regulation of cytoplasmic transport GO:1903649 112 0.014
multicellular organismal signaling GO:0035637 91 0.014
positive regulation of programmed cell death GO:0043068 218 0.014
response to radiation GO:0009314 165 0.014
glycosyl compound catabolic process GO:1901658 206 0.014
positive regulation of cell development GO:0010720 237 0.014
positive regulation of lymphocyte activation GO:0051251 140 0.014
regulation of protein kinase activity GO:0045859 232 0.014
t cell differentiation GO:0030217 174 0.014
leukocyte migration GO:0050900 124 0.014
divalent metal ion transport GO:0070838 172 0.014
cellular response to dna damage stimulus GO:0006974 207 0.014
regulation of kinase activity GO:0043549 249 0.014
regulation of mapk cascade GO:0043408 248 0.014
protein targeting GO:0006605 143 0.014
myosin filament organization GO:0031033 3 0.014
mapk cascade GO:0000165 281 0.014
protein localization to organelle GO:0033365 185 0.014
monocarboxylic acid metabolic process GO:0032787 191 0.014
guanosine containing compound metabolic process GO:1901068 144 0.013
organonitrogen compound biosynthetic process GO:1901566 192 0.013
membrane organization GO:0061024 245 0.013
regulation of natural killer cell mediated cytotoxicity GO:0042269 19 0.013
protein secretion GO:0009306 111 0.013
natural killer cell mediated cytotoxicity GO:0042267 29 0.013
cellular response to interferon beta GO:0035458 21 0.013
anatomical structure homeostasis GO:0060249 145 0.013
cell fate commitment GO:0045165 210 0.013
antigen processing and presentation via mhc class ib GO:0002475 8 0.013
Mouse
epithelial cell development GO:0002064 159 0.013
guanosine containing compound catabolic process GO:1901069 144 0.013
cellular divalent inorganic cation homeostasis GO:0072503 127 0.013
ras protein signal transduction GO:0007265 77 0.013
epithelial cell proliferation GO:0050673 174 0.013
regulation of leukocyte differentiation GO:1902105 159 0.013
interferon gamma production GO:0032609 67 0.013
Mouse
nuclear transport GO:0051169 139 0.013
regulation of body fluid levels GO:0050878 162 0.013
regulation of cell migration GO:0030334 219 0.013
extracellular matrix organization GO:0030198 147 0.013
regulation of transferase activity GO:0051338 263 0.013
b cell activation GO:0042113 161 0.013
neuronal action potential GO:0019228 54 0.013
response to nutrient levels GO:0031667 109 0.013
regulation of intracellular transport GO:0032386 159 0.013
positive regulation of cell activation GO:0050867 158 0.013
lateral inhibition GO:0046331 1 0.012
inorganic ion transmembrane transport GO:0098660 234 0.012
transmission of nerve impulse GO:0019226 76 0.012
vitamin d biosynthetic process GO:0042368 3 0.012
type i interferon production GO:0032606 29 0.012
innate immune response activating signal transduction GO:0002758 50 0.012
carbohydrate metabolic process GO:0005975 230 0.012
positive regulation of cell death GO:0010942 224 0.012
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.012
action potential GO:0001508 78 0.012
negative regulation of cell activation GO:0050866 111 0.012
cell substrate adhesion GO:0031589 130 0.012
developmental maturation GO:0021700 193 0.012
divalent inorganic cation homeostasis GO:0072507 138 0.012
lung development GO:0030324 164 0.012
cation transmembrane transport GO:0098655 266 0.012
fat cell differentiation GO:0045444 160 0.012
carbohydrate derivative biosynthetic process GO:1901137 183 0.012
regulation of innate immune response GO:0045088 91 0.012
negative regulation of cytokine production GO:0001818 84 0.012
positive regulation of protein phosphorylation GO:0001934 242 0.012
rho protein signal transduction GO:0007266 32 0.012
regulation of cellular component biogenesis GO:0044087 181 0.012
cellular ion homeostasis GO:0006873 165 0.012
microtubule based process GO:0007017 236 0.012
regulation of ion transport GO:0043269 215 0.012
fatty acid metabolic process GO:0006631 121 0.012
rhythmic process GO:0048511 174 0.012
regulation of vesicle mediated transport GO:0060627 139 0.012
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.012
locomotory behavior GO:0007626 195 0.012
skeletal system development GO:0001501 356 0.012
intrinsic apoptotic signaling pathway GO:0097193 132 0.012
regulation of neuron apoptotic process GO:0043523 122 0.012
nucleocytoplasmic transport GO:0006913 139 0.012
muscle cell differentiation GO:0042692 261 0.011
alcohol metabolic process GO:0006066 116 0.011
endocytosis GO:0006897 168 0.011
cellular alcohol metabolic process GO:0044107 3 0.011
lipid biosynthetic process GO:0008610 179 0.011
peptidyl tyrosine modification GO:0018212 145 0.011
inter male aggressive behavior GO:0002121 3 0.011
regulation of tolerance induction dependent upon immune response GO:0002652 1 0.011
wound healing GO:0042060 157 0.011
peptidyl tyrosine phosphorylation GO:0018108 143 0.011
forebrain development GO:0030900 302 0.011
extrinsic apoptotic signaling pathway GO:0097191 126 0.011
engulfment of apoptotic cell GO:0043652 3 0.011
regulation of purine nucleotide metabolic process GO:1900542 169 0.011
calcium ion homeostasis GO:0055074 127 0.011
regulation of leukocyte proliferation GO:0070663 121 0.011
natural killer cell mediated immunity GO:0002228 29 0.011
transition metal ion homeostasis GO:0055076 54 0.011
response to growth factor GO:0070848 198 0.011
defense response to gram negative bacterium GO:0050829 28 0.011
cellular component assembly involved in morphogenesis GO:0010927 139 0.011
detection of chemical stimulus involved in sensory perception of smell GO:0050911 4 0.011
regulation of lymphocyte differentiation GO:0045619 107 0.011
regulation of system process GO:0044057 200 0.011
i kappab kinase nf kappab signaling GO:0007249 85 0.011
antigen processing and presentation of endogenous peptide antigen via mhc class i GO:0019885 3 0.011
carbohydrate homeostasis GO:0033500 128 0.011
regulation of cell adhesion GO:0030155 154 0.011
glycoprotein metabolic process GO:0009100 116 0.011
steroid metabolic process GO:0008202 119 0.011
negative regulation of cellular component organization GO:0051129 194 0.011
inorganic cation transmembrane transport GO:0098662 207 0.011
protein localization to nucleus GO:0034504 121 0.011
positive regulation of peptidase activity GO:0010952 49 0.011
regulation of epithelial cell proliferation GO:0050678 141 0.011
respiratory tube development GO:0030323 167 0.011
methylation GO:0032259 134 0.011
regulation of protein ubiquitination GO:0031396 52 0.011
posttranscriptional regulation of gene expression GO:0010608 155 0.011
regulation of interleukin 10 secretion GO:2001179 4 0.011
iron ion homeostasis GO:0055072 36 0.011
regulation of cell projection organization GO:0031344 206 0.011
secondary alcohol metabolic process GO:1902652 3 0.011
glycoprotein biosynthetic process GO:0009101 89 0.011
regulation of cytokine secretion GO:0050707 61 0.011
cellular protein catabolic process GO:0044257 155 0.011
myeloid leukocyte activation GO:0002274 83 0.011
organelle assembly GO:0070925 177 0.011
cellular response to lipopolysaccharide GO:0071222 77 0.011
neuron death GO:0070997 154 0.011
gland development GO:0048732 330 0.010
pattern recognition receptor signaling pathway GO:0002221 47 0.010
gtp metabolic process GO:0046039 144 0.010
wnt signaling pathway GO:0016055 188 0.010
extracellular structure organization GO:0043062 148 0.010
spermatid differentiation GO:0048515 115 0.010
regulation of ossification GO:0030278 112 0.010
regulation of metal ion transport GO:0010959 106 0.010
anion transport GO:0006820 177 0.010
regulation of lymphocyte proliferation GO:0050670 117 0.010
modification dependent macromolecule catabolic process GO:0043632 133 0.010
regulation of t cell proliferation GO:0042129 92 0.010
negative regulation of cell development GO:0010721 169 0.010
actin cytoskeleton organization GO:0030036 220 0.010
regulation of organelle organization GO:0033043 289 0.010
modification dependent protein catabolic process GO:0019941 133 0.010
response to inorganic substance GO:0010035 96 0.010
negative regulation of lymphocyte activation GO:0051250 91 0.010
plasma membrane organization GO:0007009 90 0.010
response to interferon beta GO:0035456 22 0.010
tissue homeostasis GO:0001894 115 0.010
cellular response to organonitrogen compound GO:0071417 145 0.010
stem cell differentiation GO:0048863 268 0.010
camera type eye development GO:0043010 266 0.010
urogenital system development GO:0001655 261 0.010
establishment of organelle localization GO:0051656 122 0.010
chromatin organization GO:0006325 206 0.010

H2-T10 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.028
nervous system disease DOID:863 0 0.028
disease of metabolism DOID:0014667 0 0.019
eye and adnexa disease DOID:1492 0 0.014
sensory system disease DOID:0050155 0 0.014
central nervous system disease DOID:331 0 0.014
eye disease DOID:5614 0 0.010