Mus musculus

14 known processes

H2-T18

histocompatibility 2, T region locus 18

(Aliases: TLAg,Tla,H-2T18)

H2-T18 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
positive regulation of t cell mediated cytotoxicity GO:0001916 15 0.177
monocarboxylic acid metabolic process GO:0032787 191 0.112
cellular alcohol biosynthetic process GO:0044108 3 0.111
regulation of secretion GO:0051046 274 0.092
iron ion import GO:0097286 5 0.092
fat cell differentiation GO:0045444 160 0.092
regulation of hormone levels GO:0010817 211 0.090
regulation of system process GO:0044057 200 0.090
cation transport GO:0006812 399 0.077
regulation of cellular amine metabolic process GO:0033238 20 0.077
regulation of natural killer cell mediated immunity GO:0002715 19 0.076
muscle system process GO:0003012 141 0.070
metal ion homeostasis GO:0055065 189 0.070
regulation of response to wounding GO:1903034 189 0.068
interleukin 1 beta production GO:0032611 30 0.062
regulation of cytokine production GO:0001817 266 0.061
response to inorganic substance GO:0010035 96 0.061
cell killing GO:0001906 67 0.058
fat soluble vitamin biosynthetic process GO:0042362 4 0.057
t cell mediated immunity GO:0002456 50 0.057
reactive oxygen species metabolic process GO:0072593 84 0.057
blood vessel morphogenesis GO:0048514 285 0.056
regulation of homeostatic process GO:0032844 182 0.054
cation homeostasis GO:0055080 212 0.053
regulation of muscle system process GO:0090257 80 0.053
positive regulation of potassium ion transport GO:0043268 3 0.052
natural killer cell mediated immunity GO:0002228 29 0.052
hormone secretion GO:0046879 128 0.052
positive regulation of leukocyte mediated cytotoxicity GO:0001912 31 0.051
nucleobase containing small molecule metabolic process GO:0055086 352 0.050
transmembrane transport GO:0055085 412 0.049
regulation of secretion by cell GO:1903530 249 0.048
positive regulation of cytokine production GO:0001819 174 0.047
oxidation reduction process GO:0055114 342 0.046
calcitriol biosynthetic process from calciol GO:0036378 3 0.044
response to molecule of bacterial origin GO:0002237 143 0.043
cellular chemical homeostasis GO:0055082 215 0.041
ion transmembrane transport GO:0034220 361 0.040
activation of meiosis GO:0090427 4 0.040
regulation of cell killing GO:0031341 40 0.039
antigen processing and presentation of endogenous peptide antigen via mhc class ib GO:0002476 4 0.038
urogenital system development GO:0001655 261 0.038
renal system process GO:0003014 48 0.037
eye photoreceptor cell differentiation GO:0001754 41 0.035
camera type eye development GO:0043010 266 0.035
cellular amino acid metabolic process GO:0006520 103 0.035
negative regulation of cellular amine metabolic process GO:0033239 1 0.035
response to lipopolysaccharide GO:0032496 128 0.034
t cell activation GO:0042110 289 0.034
regulation of hydrolase activity GO:0051336 246 0.033
central nervous system neuron differentiation GO:0021953 162 0.033
naphthalene containing compound metabolic process GO:0090420 1 0.033
regulation of leukocyte mediated cytotoxicity GO:0001910 38 0.033
reactive nitrogen species metabolic process GO:2001057 0 0.032
regulation of t cell mediated cytotoxicity GO:0001914 18 0.032
vitamin d biosynthetic process GO:0042368 3 0.032
regulation of blood pressure GO:0008217 93 0.031
nucleoside phosphate catabolic process GO:1901292 222 0.031
synaptic transmission GO:0007268 329 0.031
negative regulation of monocyte extravasation GO:2000438 1 0.031
second messenger mediated signaling GO:0019932 73 0.030
negative regulation of serotonin secretion GO:0014063 2 0.030
long term synaptic potentiation GO:0060291 25 0.029
prostate gland morphogenetic growth GO:0060737 4 0.029
natural killer cell mediated cytotoxicity GO:0042267 29 0.029
fatty acid metabolic process GO:0006631 121 0.029
regulation of leukocyte mediated immunity GO:0002703 104 0.029
cellular alcohol metabolic process GO:0044107 3 0.028
secondary alcohol metabolic process GO:1902652 3 0.028
lymphocyte activation involved in immune response GO:0002285 93 0.028
regulation of blood circulation GO:1903522 93 0.028
response to organic cyclic compound GO:0014070 198 0.028
iron ion homeostasis GO:0055072 36 0.027
sensory organ morphogenesis GO:0090596 242 0.027
cellular ketone metabolic process GO:0042180 84 0.027
regulation of lymphocyte mediated immunity GO:0002706 84 0.027
inorganic ion transmembrane transport GO:0098660 234 0.027
regulation of cell migration GO:0030334 219 0.027
leukocyte activation involved in immune response GO:0002366 126 0.026
intrinsic apoptotic signaling pathway GO:0097193 132 0.026
innate immune response GO:0045087 157 0.026
cellular response to cadmium ion GO:0071276 3 0.026
neuromuscular process GO:0050905 99 0.026
regulation of saliva secretion GO:0046877 2 0.026
regulation of anatomical structure size GO:0090066 178 0.025
regulation of cellular ketone metabolic process GO:0010565 66 0.025
ear development GO:0043583 200 0.025
cytokine production GO:0001816 319 0.025
regulation of cell activation GO:0050865 289 0.025
regulation of adaptive immune response GO:0002819 90 0.025
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.025
transition metal ion transport GO:0000041 38 0.025
glycosyl compound metabolic process GO:1901657 246 0.025
regulation of thyroid hormone generation GO:2000609 4 0.025
ribonucleoside metabolic process GO:0009119 245 0.024
regulation of cellular amino acid metabolic process GO:0006521 5 0.024
polyol metabolic process GO:0019751 26 0.024
cellular response to lipopolysaccharide GO:0071222 77 0.024
spermatid differentiation GO:0048515 115 0.024
apoptotic signaling pathway GO:0097190 306 0.024
sequestering of calcium ion GO:0051208 18 0.024
response to organonitrogen compound GO:0010243 246 0.024
inorganic cation import into cell GO:0098659 4 0.024
cellular homeostasis GO:0019725 240 0.023
g protein coupled receptor internalization GO:0002031 3 0.023
blood circulation GO:0008015 195 0.023
cell activation involved in immune response GO:0002263 126 0.023
cardiac muscle cell contraction GO:0086003 7 0.023
regulation of reactive oxygen species metabolic process GO:2000377 40 0.023
heart contraction GO:0060047 93 0.023
divalent inorganic cation homeostasis GO:0072507 138 0.023
regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 33 0.023
angiogenesis GO:0001525 201 0.022
regulation of defense response GO:0031347 233 0.022
regulation of gtp catabolic process GO:0033124 113 0.022
skin development GO:0043588 220 0.022
regulation of ras protein signal transduction GO:0046578 114 0.021
somatostatin signaling pathway GO:0038170 2 0.021
leukocyte mediated cytotoxicity GO:0001909 62 0.021
antigen processing and presentation of endogenous peptide antigen via mhc class i GO:0019885 3 0.021
nucleotide catabolic process GO:0009166 217 0.021
peptidyl amino acid modification GO:0018193 336 0.020
muscle cell differentiation GO:0042692 261 0.020
regulation of purine nucleotide metabolic process GO:1900542 169 0.020
organonitrogen compound catabolic process GO:1901565 264 0.020
regulation of ion transport GO:0043269 215 0.020
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.020
locomotory behavior GO:0007626 195 0.020
regulation of membrane potential GO:0042391 192 0.020
smooth muscle contraction GO:0006939 44 0.020
regulation of heart contraction GO:0008016 77 0.020
purine nucleoside triphosphate catabolic process GO:0009146 203 0.020
immune effector process GO:0002252 321 0.020
maintenance of location GO:0051235 89 0.020
vitamin d3 metabolic process GO:0070640 3 0.020
transition metal ion homeostasis GO:0055076 54 0.020
regulation of tube size GO:0035150 57 0.020
peptide transport GO:0015833 133 0.019
nucleoside metabolic process GO:0009116 246 0.019
regulation of renal sodium excretion GO:0035813 3 0.019
positive regulation of reactive oxygen species metabolic process GO:2000379 11 0.019
glucose homeostasis GO:0042593 128 0.019
developmental maturation GO:0021700 193 0.019
insulin secretion GO:0030073 89 0.018
positive regulation of defense response GO:0031349 124 0.018
g protein coupled receptor signaling pathway GO:0007186 243 0.018
cellular divalent inorganic cation homeostasis GO:0072503 127 0.018
purine containing compound catabolic process GO:0072523 213 0.018
sulfur compound metabolic process GO:0006790 100 0.018
inflammatory response GO:0006954 244 0.018
response to acid chemical GO:0001101 111 0.018
embryonic organ morphogenesis GO:0048562 276 0.018
histamine transport GO:0051608 2 0.018
response to oxidative stress GO:0006979 123 0.018
iron ion import into cell GO:0097459 4 0.018
positive regulation of ion transport GO:0043270 65 0.018
regulation of hormone secretion GO:0046883 88 0.017
organic hydroxy compound metabolic process GO:1901615 203 0.017
spermatogenesis GO:0007283 284 0.017
dendrite development GO:0016358 115 0.017
multicellular organismal homeostasis GO:0048871 164 0.017
gtp catabolic process GO:0006184 143 0.017
positive regulation of adaptive immune response GO:0002821 61 0.017
epithelial tube morphogenesis GO:0060562 303 0.017
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 87 0.017
synapse organization GO:0050808 125 0.017
actin filament based movement GO:0030048 23 0.017
antigen processing and presentation of endogenous peptide antigen via mhc class i via er pathway GO:0002484 3 0.016
reactive oxygen species biosynthetic process GO:1903409 8 0.016
divalent metal ion transport GO:0070838 172 0.016
somatostatin receptor signaling pathway GO:0038169 2 0.016
alcohol biosynthetic process GO:0046165 43 0.016
ribonucleoside triphosphate metabolic process GO:0009199 220 0.016
response to stilbenoid GO:0035634 22 0.016
vascular process in circulatory system GO:0003018 62 0.016
regulation of heart rate GO:0002027 36 0.016
cardiac muscle contraction GO:0060048 32 0.016
cellular ion homeostasis GO:0006873 165 0.016
negative regulation of response to wounding GO:1903035 77 0.016
purine nucleoside triphosphate metabolic process GO:0009144 226 0.016
response to phenylpropanoid GO:0080184 22 0.016
positive regulation of leukocyte mediated immunity GO:0002705 70 0.015
positive regulation of cellular amine metabolic process GO:0033240 5 0.015
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.015
nitrogen compound transport GO:0071705 271 0.015
regulation of purine nucleotide catabolic process GO:0033121 122 0.015
small gtpase mediated signal transduction GO:0007264 97 0.015
cellular response to lipid GO:0071396 145 0.015
carbohydrate biosynthetic process GO:0016051 74 0.015
regulation of nucleoside metabolic process GO:0009118 130 0.015
cation transmembrane transport GO:0098655 266 0.015
regulation of protein transport GO:0051223 163 0.015
positive regulation of natural killer cell mediated immunity GO:0002717 16 0.015
purine containing compound metabolic process GO:0072521 311 0.015
potassium ion transport GO:0006813 52 0.015
regulation of monocyte extravasation GO:2000437 2 0.015
neural tube formation GO:0001841 108 0.015
monosaccharide metabolic process GO:0005996 106 0.015
regulation of transferase activity GO:0051338 263 0.015
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.014
homeostasis of number of cells GO:0048872 210 0.014
neural tube development GO:0021915 160 0.014
sensory perception of pain GO:0019233 47 0.014
mitochondrion organization GO:0007005 134 0.014
muscle contraction GO:0006936 101 0.014
circulatory system process GO:0003013 197 0.014
cellular response to cytokine stimulus GO:0071345 189 0.014
positive regulation of cell migration GO:0030335 109 0.014
positive regulation of potassium ion transmembrane transport GO:1901381 3 0.014
negative regulation of protein modification process GO:0031400 163 0.014
long chain fatty acid metabolic process GO:0001676 26 0.014
protein kinase b signaling GO:0043491 74 0.014
regulation of cell motility GO:2000145 236 0.014
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.014
nucleoside phosphate metabolic process GO:0006753 338 0.014
interleukin 1 production GO:0032612 31 0.014
regulation of t cell mediated immunity GO:0002709 34 0.014
positive regulation of cellular catabolic process GO:0031331 148 0.014
nucleoside catabolic process GO:0009164 206 0.014
axial mesoderm formation GO:0048320 3 0.014
action potential GO:0001508 78 0.014
negative regulation of protein metabolic process GO:0051248 282 0.014
embryonic epithelial tube formation GO:0001838 130 0.014
viral process GO:0016032 41 0.014
visual perception GO:0007601 52 0.014
antigen processing and presentation of endogenous peptide antigen via mhc class ib via er pathway GO:0002488 2 0.014
positive regulation of secretion GO:0051047 130 0.014
membrane depolarization during sa node cell action potential GO:0086046 2 0.013
regulation of cellular catabolic process GO:0031329 242 0.013
regulation of serotonin secretion GO:0014062 3 0.013
retina development in camera type eye GO:0060041 119 0.013
nucleotide metabolic process GO:0009117 332 0.013
positive regulation of natural killer cell mediated cytotoxicity GO:0045954 16 0.013
positive regulation of immune effector process GO:0002699 107 0.013
fertilization GO:0009566 127 0.013
positive regulation of innate immune response GO:0045089 80 0.013
ribose phosphate metabolic process GO:0019693 291 0.013
naphthalene metabolic process GO:0018931 1 0.013
cellular metal ion homeostasis GO:0006875 151 0.013
cellular response to epidermal growth factor stimulus GO:0071364 4 0.013
response to pain GO:0048265 26 0.013
antigen processing and presentation of endogenous peptide antigen GO:0002483 6 0.012
antigen processing and presentation of exogenous peptide antigen via mhc class ib GO:0002477 3 0.012
regulation of binding GO:0051098 111 0.012
renal sodium excretion GO:0035812 3 0.012
antigen processing and presentation via mhc class ib GO:0002475 8 0.012
muscle tissue development GO:0060537 308 0.012
regulation of store operated calcium channel activity GO:1901339 1 0.012
negative regulation of cellular protein metabolic process GO:0032269 247 0.012
actin mediated cell contraction GO:0070252 15 0.012
photoreceptor cell differentiation GO:0046530 52 0.012
carbohydrate transport GO:0008643 62 0.012
ribonucleotide metabolic process GO:0009259 291 0.012
regulation of ion homeostasis GO:2000021 64 0.012
protein processing GO:0016485 163 0.012
positive regulation of secretion by cell GO:1903532 114 0.012
b 1 b cell differentiation GO:0001923 3 0.012
positive regulation of homeostatic process GO:0032846 64 0.012
lymphocyte mediated immunity GO:0002449 139 0.012
regulation of fat cell differentiation GO:0045598 81 0.012
regulation of action potential GO:0098900 4 0.012
negative regulation of organelle organization GO:0010639 90 0.012
exocytosis GO:0006887 121 0.012
embryonic camera type eye development GO:0031076 36 0.012
positive regulation of synaptic growth at neuromuscular junction GO:0045887 1 0.012
cellular response to organonitrogen compound GO:0071417 145 0.011
calcium ion transport into cytosol GO:0060402 48 0.011
regulation of nucleotide metabolic process GO:0006140 169 0.011
neuronal action potential GO:0019228 54 0.011
epithelial cell development GO:0002064 159 0.011
peptide hormone secretion GO:0030072 109 0.011
heterocycle catabolic process GO:0046700 280 0.011
protein maturation GO:0051604 176 0.011
inorganic cation transmembrane transport GO:0098662 207 0.011
cytokine mediated signaling pathway GO:0019221 115 0.011
cellular amine metabolic process GO:0044106 44 0.011
regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis GO:0072039 4 0.011
purine ribonucleotide metabolic process GO:0009150 290 0.011
aromatic compound catabolic process GO:0019439 286 0.011
cellular response to acid chemical GO:0071229 68 0.011
regulation of proteolysis GO:0030162 164 0.011
positive regulation of nervous system development GO:0051962 221 0.011
sodium ion homeostasis GO:0055078 7 0.011
purine nucleoside metabolic process GO:0042278 241 0.011
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 61 0.011
sensory perception GO:0007600 245 0.011
norepinephrine epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure GO:0001994 3 0.011
organophosphate catabolic process GO:0046434 232 0.011
skeletal muscle organ development GO:0060538 163 0.011
ribonucleoside triphosphate catabolic process GO:0009203 199 0.011
inclusion body assembly GO:0070841 3 0.011
dephosphorylation GO:0016311 129 0.011
extracellular structure organization GO:0043062 148 0.011
positive regulation of nucleoside metabolic process GO:0045979 91 0.011
cellular nitrogen compound catabolic process GO:0044270 280 0.011
t cell activation involved in immune response GO:0002286 43 0.011
adaptive immune response GO:0002250 155 0.011
regulation of feeding behavior GO:0060259 3 0.011
macromolecule methylation GO:0043414 120 0.011
regulation of ion transmembrane transport GO:0034765 119 0.011
monocyte extravasation GO:0035696 2 0.011
purine nucleotide metabolic process GO:0006163 302 0.011
regulation of inflammatory response GO:0050727 147 0.010
muscle adaptation GO:0043500 39 0.010
positive regulation of cytosolic calcium ion concentration GO:0007204 65 0.010
regulation of cellular component biogenesis GO:0044087 181 0.010
regulation of intracellular transport GO:0032386 159 0.010
negative regulation of immune system process GO:0002683 209 0.010
pigment metabolic process GO:0042440 32 0.010
defense response to bacterium GO:0042742 119 0.010
alpha beta t cell activation involved in immune response GO:0002287 31 0.010
rho protein signal transduction GO:0007266 32 0.010
amine metabolic process GO:0009308 45 0.010
hair follicle development GO:0001942 85 0.010
regulation of blood vessel size GO:0050880 56 0.010
purine nucleoside catabolic process GO:0006152 205 0.010
cellular lipid metabolic process GO:0044255 323 0.010
serotonin receptor signaling pathway GO:0007210 8 0.010
organ growth GO:0035265 117 0.010
morphogenesis of embryonic epithelium GO:0016331 159 0.010
protein localization to membrane GO:0072657 108 0.010
response to peptide hormone GO:0043434 127 0.010
male gamete generation GO:0048232 285 0.010
endomembrane system organization GO:0010256 147 0.010
mesenchymal cell apoptotic process involved in nephron morphogenesis GO:1901145 4 0.010
cellular carbohydrate metabolic process GO:0044262 119 0.010
cytokine production involved in immune response GO:0002367 34 0.010
chondrocyte hypertrophy GO:0003415 4 0.010
regulation of circadian sleep wake cycle GO:0042749 3 0.010
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.010
positive regulation of the force of heart contraction by epinephrine norepinephrine GO:0001997 3 0.010

H2-T18 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
nervous system disease DOID:863 0 0.012
neurodegenerative disease DOID:1289 0 0.012
disease of anatomical entity DOID:7 0 0.012
central nervous system disease DOID:331 0 0.012
disease of metabolism DOID:0014667 0 0.010