Mus musculus

0 known processes

Slpi

secretory leukocyte peptidase inhibitor

Slpi biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
defense response to other organism GO:0098542 197 0.739
inflammatory response GO:0006954 244 0.652
immune effector process GO:0002252 321 0.611
positive regulation of cytokine production GO:0001819 174 0.544
positive regulation of defense response GO:0031349 124 0.472
regulation of secretion GO:0051046 274 0.465
defense response to bacterium GO:0042742 119 0.458
wound healing involved in inflammatory response GO:0002246 4 0.454
regulation of inflammatory response GO:0050727 147 0.445
cellular chemical homeostasis GO:0055082 215 0.443
regulation of chemokine production GO:0032642 30 0.439
cytokine production GO:0001816 319 0.436
positive regulation of protein transport GO:0051222 93 0.429
response to lipopolysaccharide GO:0032496 128 0.425
regulation of adiponectin secretion GO:0070163 2 0.420
neutrophil chemotaxis GO:0030593 36 0.415
regulation of defense response GO:0031347 233 0.391
regulation of cell activation GO:0050865 289 0.381
regulation of cytokine production GO:0001817 266 0.365
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.365
positive regulation of cytokine secretion GO:0050715 41 0.328
regulation of protein transport GO:0051223 163 0.277
acute inflammatory response GO:0002526 41 0.276
regulation of chemokine secretion GO:0090196 4 0.267
interaction with symbiont GO:0051702 14 0.262
positive regulation of neutrophil mediated killing of symbiont cell GO:0070961 1 0.261
innate immune response activating signal transduction GO:0002758 50 0.253
positive regulation of natural killer cell chemotaxis GO:2000503 1 0.245
protein secretion GO:0009306 111 0.237
nitrogen compound transport GO:0071705 271 0.236
response to molecule of bacterial origin GO:0002237 143 0.223
cytokine secretion GO:0050663 72 0.215
cytokine biosynthetic process GO:0042089 68 0.215
leukocyte differentiation GO:0002521 342 0.208
regulation of cytokine secretion GO:0050707 61 0.205
killing by host of symbiont cells GO:0051873 11 0.200
adiponectin secretion GO:0070162 2 0.199
leukocyte mediated immunity GO:0002443 174 0.198
leukocyte chemotaxis GO:0030595 69 0.197
regulation of protein secretion GO:0050708 82 0.196
jnk cascade GO:0007254 72 0.196
neutrophil mediated killing of fungus GO:0070947 3 0.191
positive regulation of tumor necrosis factor superfamily cytokine production GO:1903557 31 0.187
regulation of response to wounding GO:1903034 189 0.185
myeloid leukocyte mediated immunity GO:0002444 42 0.183
positive regulation of secretion by cell GO:1903532 114 0.178
tumor necrosis factor production GO:0032640 50 0.178
positive regulation of leukocyte differentiation GO:1902107 86 0.174
regulation of multi organism process GO:0043900 111 0.174
Human
regulation of neutrophil mediated killing of gram negative bacterium GO:0070951 1 0.168
regulation of stress activated mapk cascade GO:0032872 69 0.162
wound healing GO:0042060 157 0.160
defense response to virus GO:0051607 68 0.158
multicellular organismal homeostasis GO:0048871 164 0.157
cellular response to cytokine stimulus GO:0071345 189 0.153
positive regulation of secretion GO:0051047 130 0.153
regulation of secretion by cell GO:1903530 249 0.152
adaptive immune response GO:0002250 155 0.151
negative regulation of lymphocyte activation GO:0051250 91 0.150
regulation of innate immune response GO:0045088 91 0.147
metal ion homeostasis GO:0055065 189 0.144
regulation of tumor necrosis factor superfamily cytokine production GO:1903555 50 0.142
regulation of interleukin 6 production GO:0032675 55 0.141
regulation of protein localization GO:0032880 231 0.139
toll like receptor signaling pathway GO:0002224 38 0.137
negative regulation of immune system process GO:0002683 209 0.136
regulation of cellular response to stress GO:0080135 159 0.135
cation homeostasis GO:0055080 212 0.135
positive regulation of monocyte chemotaxis GO:0090026 2 0.133
leukocyte migration GO:0050900 124 0.133
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 87 0.130
cellular ketone metabolic process GO:0042180 84 0.128
innate immune response GO:0045087 157 0.126
symbiosis encompassing mutualism through parasitism GO:0044403 83 0.123
Human
negative regulation of multi organism process GO:0043901 68 0.123
Human
leukocyte activation involved in immune response GO:0002366 126 0.123
positive regulation of neutrophil mediated cytotoxicity GO:0070960 1 0.123
negative regulation of cytokine production GO:0001818 84 0.122
modification of morphology or physiology of other organism GO:0035821 18 0.120
antibacterial humoral response GO:0019731 8 0.119
chemotaxis GO:0006935 247 0.118
inflammatory response to wounding GO:0090594 4 0.116
positive regulation of protein secretion GO:0050714 52 0.115
regulation of lymphocyte activation GO:0051249 240 0.114
regulation of mast cell activation GO:0033003 21 0.113
positive regulation of chemokine secretion GO:0090197 4 0.112
myeloid cell differentiation GO:0030099 233 0.111
positive regulation of cellular amine metabolic process GO:0033240 5 0.109
positive regulation of acute inflammatory response GO:0002675 16 0.109
regulation of tumor necrosis factor production GO:0032680 49 0.109
regulation of establishment of protein localization GO:0070201 181 0.109
positive regulation of chemokine production GO:0032722 22 0.108
organic anion transport GO:0015711 137 0.105
t cell activation GO:0042110 289 0.103
cytokine metabolic process GO:0042107 71 0.103
regulation of cellular amine metabolic process GO:0033238 20 0.100
macromolecule catabolic process GO:0009057 281 0.099
positive regulation of jnk cascade GO:0046330 46 0.098
regulation of homeostatic process GO:0032844 182 0.098
positive regulation of cytokine biosynthetic process GO:0042108 40 0.097
production of molecular mediator of immune response GO:0002440 103 0.096
calcium ion homeostasis GO:0055074 127 0.095
i kappab kinase nf kappab signaling GO:0007249 85 0.095
cellular amine metabolic process GO:0044106 44 0.095
interleukin 8 production GO:0032637 4 0.094
chemokine production GO:0032602 34 0.094
positive regulation of innate immune response GO:0045089 80 0.093
regulation of cellular amino acid metabolic process GO:0006521 5 0.093
positive regulation of transferase activity GO:0051347 167 0.092
regulation of leukocyte mediated immunity GO:0002703 104 0.092
regulation of cytokine biosynthetic process GO:0042035 59 0.091
neutrophil mediated killing of gram negative bacterium GO:0070945 4 0.090
positive regulation of neutrophil chemotaxis GO:0090023 12 0.090
response to acid chemical GO:0001101 111 0.089
positive regulation of homeostatic process GO:0032846 64 0.089
cellular ion homeostasis GO:0006873 165 0.088
regulation of vesicle mediated transport GO:0060627 139 0.087
amide transport GO:0042886 138 0.087
regulation of map kinase activity GO:0043405 120 0.087
regulation of acute inflammatory response GO:0002673 27 0.086
stress activated protein kinase signaling cascade GO:0031098 81 0.085
regulation of jnk cascade GO:0046328 62 0.085
lymphocyte activation involved in immune response GO:0002285 93 0.083
killing of cells in other organism involved in symbiotic interaction GO:0051883 13 0.083
positive regulation of immunoglobulin production in mucosal tissue GO:2000558 1 0.082
activation of innate immune response GO:0002218 56 0.082
immune response activating signal transduction GO:0002757 116 0.080
humoral immune response GO:0006959 57 0.079
cell chemotaxis GO:0060326 81 0.079
regulation of vascular endothelial growth factor production GO:0010574 13 0.078
tumor necrosis factor superfamily cytokine production GO:0071706 51 0.078
peptidyl amino acid modification GO:0018193 336 0.077
negative regulation of lipopolysaccharide mediated signaling pathway GO:0031665 3 0.077
regulation of endocytosis GO:0030100 69 0.077
myotube cell development GO:0014904 60 0.076
cellular response to lipopolysaccharide GO:0071222 77 0.075
positive regulation of programmed cell death GO:0043068 218 0.075
neutrophil mediated immunity GO:0002446 19 0.074
regulation of hormone levels GO:0010817 211 0.074
negative regulation of mast cell degranulation GO:0043305 4 0.074
cell activation involved in immune response GO:0002263 126 0.073
lymphocyte mediated immunity GO:0002449 139 0.073
detection of molecule of bacterial origin GO:0032490 2 0.073
positive regulation of inflammatory response GO:0050729 47 0.073
positive regulation of response to wounding GO:1903036 66 0.073
apoptotic signaling pathway GO:0097190 306 0.072
regulation of protein kinase activity GO:0045859 232 0.072
regulation of natural killer cell chemotaxis GO:2000501 1 0.072
b cell chemotaxis GO:0035754 3 0.071
regulation of adaptive immune response GO:0002819 90 0.070
positive regulation of dendritic cell dendrite assembly GO:2000549 1 0.070
cellular calcium ion homeostasis GO:0006874 119 0.070
interspecies interaction between organisms GO:0044419 83 0.070
Human
granulocyte chemotaxis GO:0071621 39 0.070
g protein coupled receptor signaling pathway GO:0007186 243 0.069
rho protein signal transduction GO:0007266 32 0.069
chemokine metabolic process GO:0050755 10 0.069
cation transport GO:0006812 399 0.069
leukocyte apoptotic process GO:0071887 71 0.068
negative regulation of cell activation GO:0050866 111 0.068
ras protein signal transduction GO:0007265 77 0.068
cytokine production involved in immune response GO:0002367 34 0.067
regulation of macrophage activation GO:0043030 17 0.067
antibacterial peptide biosynthetic process GO:0002780 2 0.067
neutrophil mediated killing of bacterium GO:0070944 6 0.066
regulation of t cell activation GO:0050863 170 0.066
negative regulation of adaptive immune response GO:0002820 25 0.066
regulation of myeloid leukocyte mediated immunity GO:0002886 25 0.065
positive regulation of t helper 1 cell differentiation GO:0045627 4 0.065
cellular amino acid metabolic process GO:0006520 103 0.064
small molecule biosynthetic process GO:0044283 132 0.064
response to organic cyclic compound GO:0014070 198 0.063
anion transport GO:0006820 177 0.063
detection of fungus GO:0016046 2 0.063
disruption by host of symbiont cells GO:0051852 11 0.062
reactive oxygen species metabolic process GO:0072593 84 0.062
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.062
cellular metal ion homeostasis GO:0006875 151 0.062
positive regulation of t cell extravasation GO:2000409 2 0.062
positive regulation of immune effector process GO:0002699 107 0.061
regulation of immunoglobulin production in mucosal tissue GO:2000557 1 0.061
positive regulation of jun kinase activity GO:0043507 30 0.061
regulation of vasculature development GO:1901342 88 0.061
positive regulation of b cell chemotaxis GO:2000538 2 0.061
blood vessel morphogenesis GO:0048514 285 0.060
cytosolic calcium ion homeostasis GO:0051480 70 0.060
interleukin 6 production GO:0032635 58 0.060
positive regulation of cell motility GO:2000147 116 0.059
positive regulation of granulocyte chemotaxis GO:0071624 12 0.059
disruption of cells of other organism involved in symbiotic interaction GO:0051818 13 0.058
regulation of epithelial cell proliferation GO:0050678 141 0.058
neutrophil mediated cytotoxicity GO:0070942 8 0.057
regulation of protein serine threonine kinase activity GO:0071900 157 0.057
positive regulation of angiogenesis GO:0045766 46 0.056
alpha beta t cell activation involved in immune response GO:0002287 31 0.056
extrinsic apoptotic signaling pathway GO:0097191 126 0.056
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.056
mapk cascade GO:0000165 281 0.055
antimicrobial peptide production GO:0002775 2 0.055
mature dendritic cell differentiation GO:0097029 3 0.055
positive regulation of cell activation GO:0050867 158 0.055
neutrophil migration GO:1990266 37 0.055
antimicrobial peptide biosynthetic process GO:0002777 2 0.054
monocarboxylic acid biosynthetic process GO:0072330 61 0.054
positive regulation of intracellular transport GO:0032388 70 0.054
negative regulation of growth of symbiont involved in interaction with host GO:0044146 19 0.054
regulation of mapk cascade GO:0043408 248 0.054
natural killer cell chemotaxis GO:0035747 1 0.054
carboxylic acid biosynthetic process GO:0046394 86 0.054
response to arsenic containing substance GO:0046685 5 0.053
positive regulation of lymphocyte differentiation GO:0045621 61 0.053
homeostasis of number of cells GO:0048872 210 0.053
regulation of interferon gamma production GO:0032649 57 0.053
myeloid leukocyte migration GO:0097529 57 0.052
cell killing GO:0001906 67 0.052
positive regulation of kinase activity GO:0033674 155 0.051
divalent inorganic cation homeostasis GO:0072507 138 0.051
purinergic nucleotide receptor signaling pathway GO:0035590 3 0.051
cytokine mediated signaling pathway GO:0019221 115 0.051
amine metabolic process GO:0009308 45 0.051
epithelial cell proliferation GO:0050673 174 0.051
protein catabolic process GO:0030163 221 0.051
antibacterial peptide secretion GO:0002779 1 0.051
positive regulation of cell migration GO:0030335 109 0.050
immune response regulating signaling pathway GO:0002764 125 0.050
positive regulation of stress activated mapk cascade GO:0032874 48 0.050
positive regulation of cytosolic calcium ion concentration GO:0007204 65 0.050
interleukin 18 mediated signaling pathway GO:0035655 2 0.050
regulation of neutrophil mediated killing of bacterium GO:0070950 1 0.049
blood coagulation GO:0007596 76 0.049
activation of mapk activity GO:0000187 59 0.049
positive regulation of lymphocyte mediated immunity GO:0002708 62 0.049
positive regulation of chemokine biosynthetic process GO:0045080 6 0.049
single organism cell adhesion GO:0098602 156 0.049
regulation of growth of symbiont in host GO:0044126 19 0.048
defense response to gram positive bacterium GO:0050830 50 0.048
regulation of exocytosis GO:0017157 61 0.048
cellular response to organonitrogen compound GO:0071417 145 0.048
defense response to fungus GO:0050832 12 0.048
regulation of cell motility GO:2000145 236 0.048
regulation of mast cell degranulation GO:0043304 16 0.048
cellular divalent inorganic cation homeostasis GO:0072503 127 0.047
serotonin secretion by mast cell GO:0002552 1 0.047
cd4 positive alpha beta t cell differentiation involved in immune response GO:0002294 28 0.047
negative regulation of protein metabolic process GO:0051248 282 0.047
regulation of neutrophil chemotaxis GO:0090022 14 0.047
angiogenesis GO:0001525 201 0.046
positive regulation of interleukin 6 production GO:0032755 37 0.046
organic acid biosynthetic process GO:0016053 86 0.046
regulation of immunoglobulin mediated immune response GO:0002889 37 0.045
positive regulation of macrophage activation GO:0043032 10 0.045
negative regulation of macrophage chemotaxis GO:0010760 1 0.045
activation of jun kinase activity GO:0007257 15 0.045
cellular response to molecule of bacterial origin GO:0071219 83 0.045
positive regulation of mapk cascade GO:0043410 170 0.044
skeletal muscle fiber development GO:0048741 58 0.044
peptide secretion GO:0002790 114 0.044
fatty acid biosynthetic process GO:0006633 41 0.044
positive regulation of protein kinase activity GO:0045860 144 0.043
regulation of acute inflammatory response to non antigenic stimulus GO:0002877 2 0.043
reactive nitrogen species metabolic process GO:2001057 0 0.043
t helper 1 cell differentiation GO:0045063 13 0.042
t cell mediated immunity GO:0002456 50 0.042
peptide transport GO:0015833 133 0.042
regulation of angiogenesis GO:0045765 81 0.042
positive regulation of leukocyte mediated immunity GO:0002705 70 0.042
myeloid cell apoptotic process GO:0033028 22 0.042
cellular homeostasis GO:0019725 240 0.041
positive regulation of myeloid leukocyte mediated immunity GO:0002888 14 0.041
innate immune response in mucosa GO:0002227 3 0.040
t helper cell differentiation GO:0042093 28 0.040
regulation of skeletal muscle fiber development GO:0048742 36 0.040
regulation of leukocyte differentiation GO:1902105 159 0.040
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 52 0.040
Human
negative regulation of response to wounding GO:1903035 77 0.040
regulation of production of molecular mediator of immune response GO:0002700 65 0.040
killing of cells of other organism GO:0031640 13 0.039
cellular response to acid chemical GO:0071229 68 0.039
second messenger mediated signaling GO:0019932 73 0.039
regulation of b cell mediated immunity GO:0002712 37 0.039
myeloid leukocyte differentiation GO:0002573 119 0.039
regulation of cell adhesion GO:0030155 154 0.039
b cell mediated immunity GO:0019724 71 0.039
granulocyte migration GO:0097530 43 0.039
regulation of t cell differentiation GO:0045580 83 0.038
positive regulation of apoptotic process GO:0043065 217 0.038
endocytosis GO:0006897 168 0.038
regulation of lymphocyte mediated immunity GO:0002706 84 0.038
negative regulation of cellular component organization GO:0051129 194 0.038
muscle fiber development GO:0048747 76 0.038
regulation of angiotensin levels in blood GO:0002002 4 0.038
immune response regulating cell surface receptor signaling pathway GO:0002768 80 0.038
t cell activation involved in immune response GO:0002286 43 0.038
regulation of cellular ketone metabolic process GO:0010565 66 0.037
regulation of transferase activity GO:0051338 263 0.037
regulation of body fluid levels GO:0050878 162 0.037
fatty acid derivative biosynthetic process GO:1901570 15 0.037
regulation of neutrophil mediated killing of symbiont cell GO:0070949 2 0.037
hormone secretion GO:0046879 128 0.037
myeloid cell activation involved in immune response GO:0002275 34 0.037
regulation of interleukin 8 production GO:0032677 3 0.037
t helper 1 type immune response GO:0042088 25 0.037
t cell proliferation GO:0042098 120 0.037
pattern recognition receptor signaling pathway GO:0002221 47 0.037
regulation of cell migration GO:0030334 219 0.037
neutrophil mediated killing of symbiont cell GO:0070943 8 0.037
negative regulation of serotonin secretion GO:0014063 2 0.036
positive regulation of t cell activation GO:0050870 101 0.036
cellular response to lipid GO:0071396 145 0.036
positive regulation of ion transport GO:0043270 65 0.035
regulation of ion transport GO:0043269 215 0.035
positive regulation of chemotaxis GO:0050921 38 0.035
response to organonitrogen compound GO:0010243 246 0.035
lipid transport GO:0006869 98 0.035
organic acid transport GO:0015849 101 0.034
negative regulation of chemokine production GO:0032682 4 0.034
regulation of defense response to fungus GO:1900150 1 0.034
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 61 0.034
positive regulation of hematopoietic stem cell proliferation GO:1902035 2 0.034
inflammatory response to antigenic stimulus GO:0002437 30 0.034
regulation of toll like receptor signaling pathway GO:0034121 20 0.034
regulation of apoptotic signaling pathway GO:2001233 197 0.033
membrane organization GO:0061024 245 0.033
negative regulation of immune effector process GO:0002698 55 0.033
immunoglobulin production in mucosal tissue GO:0002426 3 0.033
positive regulation of toll like receptor 4 signaling pathway GO:0034145 1 0.033
production of molecular mediator involved in inflammatory response GO:0002532 21 0.033
regulation of defense response to bacterium GO:1900424 3 0.033
regulation of reactive oxygen species metabolic process GO:2000377 40 0.033
neutrophil mediated killing of gram positive bacterium GO:0070946 2 0.032
regulation of toll like receptor 4 signaling pathway GO:0034143 4 0.032
regulation of intracellular transport GO:0032386 159 0.032
regulation of type ii hypersensitivity GO:0002892 4 0.032
cd4 positive alpha beta t cell cytokine production GO:0035743 4 0.032
defense response to gram negative bacterium GO:0050829 28 0.032
lipid localization GO:0010876 126 0.032
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger GO:0007187 55 0.032
regulation of jun kinase activity GO:0043506 40 0.032
positive regulation of map kinase activity GO:0043406 84 0.032
regulation of leukocyte proliferation GO:0070663 121 0.032
positive regulation of tumor necrosis factor production GO:0032760 30 0.032
regulation of neutrophil apoptotic process GO:0033029 1 0.032
immunoglobulin transcytosis in epithelial cells GO:0002414 2 0.032
positive regulation of type 2 immune response GO:0002830 9 0.031
positive regulation of killing of cells of other organism GO:0051712 3 0.031
t helper 1 cell cytokine production GO:0035744 1 0.031
negative regulation of growth GO:0045926 99 0.031
syncytium formation by plasma membrane fusion GO:0000768 42 0.031
positive regulation of phagocytosis GO:0050766 26 0.031
positive regulation of t cell differentiation GO:0045582 52 0.031
exocytosis GO:0006887 121 0.031
positive regulation of cell death GO:0010942 224 0.031
regulation of protein kinase b signaling GO:0051896 56 0.031
positive regulation of interleukin 8 production GO:0032757 2 0.030
oxidation reduction process GO:0055114 342 0.030
circulatory system process GO:0003013 197 0.030
regulation of lymphocyte proliferation GO:0050670 117 0.030
thymocyte migration GO:0072679 2 0.030
chemokine biosynthetic process GO:0042033 8 0.030
stress activated mapk cascade GO:0051403 80 0.030
mature natural killer cell chemotaxis GO:0035782 1 0.029
connective tissue replacement involved in inflammatory response wound healing GO:0002248 3 0.029
microglia development GO:0014005 2 0.029
response to inorganic substance GO:0010035 96 0.029
cd4 positive alpha beta t cell proliferation GO:0035739 2 0.029
positive regulation of t helper 1 cell cytokine production GO:2000556 1 0.029
cellular response to biotic stimulus GO:0071216 92 0.029
striated muscle tissue development GO:0014706 293 0.029
arachidonic acid metabolite production involved in inflammatory response GO:0002538 2 0.029
regulation of t helper 1 type immune response GO:0002825 17 0.029
blood circulation GO:0008015 195 0.028
positive regulation of toll like receptor 9 signaling pathway GO:0034165 2 0.028
alpha beta t cell activation GO:0046631 91 0.028
coagulation GO:0050817 78 0.028
response to extracellular stimulus GO:0009991 127 0.028
cell type specific apoptotic process GO:0097285 268 0.028
regulation of leukocyte apoptotic process GO:2000106 56 0.028
lipid biosynthetic process GO:0008610 179 0.028
epidermis development GO:0008544 187 0.027
regulation of cellular component biogenesis GO:0044087 181 0.027
regulation of muscle tissue development GO:1901861 97 0.027
positive regulation of macrophage chemotaxis GO:0010759 5 0.027
amino sugar catabolic process GO:0046348 1 0.027
response to insulin GO:0032868 100 0.027
regulation of lymphocyte differentiation GO:0045619 107 0.027
regulation of myotube differentiation GO:0010830 62 0.027
muscle cell differentiation GO:0042692 261 0.027
protein processing GO:0016485 163 0.027
positive regulation of lymphocyte proliferation GO:0050671 70 0.027
regulation of mast cell activation involved in immune response GO:0033006 17 0.027
mast cell activation involved in immune response GO:0002279 20 0.026
negative regulation of defense response GO:0031348 77 0.026
negative regulation of leukocyte mediated immunity GO:0002704 29 0.026
interferon gamma production GO:0032609 67 0.026
leukocyte proliferation GO:0070661 172 0.026
tissue remodeling GO:0048771 102 0.026
organonitrogen compound biosynthetic process GO:1901566 192 0.026
regulation of t helper 2 cell cytokine production GO:2000551 3 0.026
mucosal immune response GO:0002385 13 0.026
regulation of t helper 1 cell cytokine production GO:2000554 1 0.025
regulation of killing of cells of other organism GO:0051709 4 0.025
astrocyte cell migration GO:0043615 3 0.025
negative regulation of cell proliferation GO:0008285 296 0.025
icosanoid metabolic process GO:0006690 33 0.025
cellular response to organic cyclic compound GO:0071407 87 0.025
eosinophil migration GO:0072677 3 0.025
regulation of rho protein signal transduction GO:0035023 71 0.025
negative regulation of leukocyte degranulation GO:0043301 7 0.025
myeloid leukocyte activation GO:0002274 83 0.025
regulation of systemic arterial blood pressure by circulatory renin angiotensin GO:0001991 13 0.025
negative regulation of proteolysis GO:0045861 74 0.025
posttranscriptional regulation of gene expression GO:0010608 155 0.025
striated muscle cell development GO:0055002 125 0.024
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 55 0.024
alpha beta t cell differentiation involved in immune response GO:0002293 30 0.024
negative regulation of muscle cell differentiation GO:0051148 33 0.024
regulation of organelle organization GO:0033043 289 0.024
tissue homeostasis GO:0001894 115 0.024
positive regulation of eosinophil migration GO:2000418 2 0.024
glucose transport GO:0015758 56 0.024
regulation of vitamin d biosynthetic process GO:0060556 1 0.024
maintenance of location GO:0051235 89 0.024
positive regulation of membrane protein ectodomain proteolysis GO:0051044 3 0.024
regulation of chemokine biosynthetic process GO:0045073 8 0.024
calcium mediated signaling GO:0019722 46 0.024
extracellular matrix organization GO:0030198 147 0.024
small gtpase mediated signal transduction GO:0007264 97 0.024
regulation of syncytium formation by plasma membrane fusion GO:0060142 23 0.023
protein localization to organelle GO:0033365 185 0.023
cell adhesion GO:0007155 329 0.023
response to transforming growth factor beta GO:0071559 88 0.023
regulation of monocyte chemotaxis GO:0090025 3 0.023
protein targeting GO:0006605 143 0.023
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.023
negative regulation of t cell activation GO:0050868 65 0.023
lymphocyte differentiation GO:0030098 242 0.023
response to peptide hormone GO:0043434 127 0.023
regulation of neutrophil mediated cytotoxicity GO:0070948 2 0.023
detection of bacterium GO:0016045 7 0.023
regulation of blood coagulation GO:0030193 28 0.023
leukotriene production involved in inflammatory response GO:0002540 2 0.023
bone resorption GO:0045453 38 0.023
positive regulation of acute inflammatory response to non antigenic stimulus GO:0002879 2 0.022
cd4 positive alpha beta t cell activation GO:0035710 45 0.022
regulation of hematopoietic stem cell proliferation GO:1902033 3 0.022
cell surface pattern recognition receptor signaling pathway GO:0002752 2 0.022
response to tumor necrosis factor GO:0034612 26 0.022
unsaturated fatty acid metabolic process GO:0033559 31 0.022
negative regulation of macrophage apoptotic process GO:2000110 3 0.022
leukocyte aggregation GO:0070486 1 0.022
single organismal cell cell adhesion GO:0016337 131 0.022
regulation of peptide transport GO:0090087 91 0.022
regulation of neutrophil mediated killing of fungus GO:0070953 1 0.022
negative regulation of intracellular signal transduction GO:1902532 167 0.022
protein maturation GO:0051604 176 0.021
cd4 positive alpha beta t cell differentiation GO:0043367 41 0.021
cellular macromolecule catabolic process GO:0044265 206 0.021
hemostasis GO:0007599 78 0.021
response to radiation GO:0009314 165 0.021
interleukin 12 production GO:0032615 32 0.021
regulation of striated muscle cell differentiation GO:0051153 81 0.021
lipoprotein metabolic process GO:0042157 43 0.021
negative regulation of apoptotic signaling pathway GO:2001234 104 0.021
keratinocyte migration GO:0051546 3 0.021
regulation of thymocyte migration GO:2000410 2 0.021
macrophage differentiation GO:0030225 20 0.021
sequestering of calcium ion GO:0051208 18 0.021
response to purine containing compound GO:0014074 28 0.021
acute phase response GO:0006953 10 0.021
cdc42 protein signal transduction GO:0032488 0 0.021
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 61 0.021
positive regulation of interferon gamma production GO:0032729 39 0.021
positive regulation of leukocyte proliferation GO:0070665 73 0.021
action potential GO:0001508 78 0.021
carbohydrate transport GO:0008643 62 0.021
regulation of granulocyte macrophage colony stimulating factor production GO:0032645 3 0.021
negative regulation of cellular protein metabolic process GO:0032269 247 0.021
positive regulation of interleukin 12 production GO:0032735 21 0.020
extracellular structure organization GO:0043062 148 0.020
regulation of cytoplasmic transport GO:1903649 112 0.020
platelet activation GO:0030168 40 0.020
antibacterial peptide production GO:0002778 2 0.020
phosphatidylethanolamine biosynthetic process GO:0006646 2 0.020
modification by host of symbiont morphology or physiology GO:0051851 12 0.020
negative regulation of growth of symbiont in host GO:0044130 19 0.020
alcohol metabolic process GO:0006066 116 0.020
response to atp GO:0033198 8 0.020
regulation of toll like receptor 9 signaling pathway GO:0034163 3 0.020
regulation of protein catabolic process GO:0042176 108 0.020
regulation of serotonin secretion GO:0014062 3 0.020
regulation of toll like receptor 2 signaling pathway GO:0034135 3 0.020
interleukin 33 mediated signaling pathway GO:0038172 1 0.020
regulation of hydrolase activity GO:0051336 246 0.020

Slpi disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.039
disease of cellular proliferation DOID:14566 0 0.039
organ system cancer DOID:0050686 0 0.039
gastrointestinal system cancer DOID:3119 0 0.027