Mus musculus

25 known processes

Trp53bp1

transformation related protein 53 binding protein 1

(Aliases: MGC100303,53BP1,Tp53bp1,m53BP1)

Trp53bp1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
protein modification by small protein conjugation or removal GO:0070647 207 0.642
protein catabolic process GO:0030163 221 0.630
immune effector process GO:0002252 321 0.417
protein modification by small protein conjugation GO:0032446 187 0.413
protein ubiquitination GO:0016567 171 0.295
telomere maintenance in response to dna damage GO:0043247 4 0.286
dna metabolic process GO:0006259 303 0.275
macromolecule catabolic process GO:0009057 281 0.261
adaptive immune response GO:0002250 155 0.244
protection from non homologous end joining at telomere GO:0031848 4 0.240
leukocyte mediated immunity GO:0002443 174 0.235
cellular response to dna damage stimulus GO:0006974 207 0.225
cellular amine metabolic process GO:0044106 44 0.212
protein polyubiquitination GO:0000209 33 0.207
positive regulation of organelle organization GO:0010638 128 0.206
cellular macromolecule catabolic process GO:0044265 206 0.205
regulation of cellular amino acid metabolic process GO:0006521 5 0.203
protein methylation GO:0006479 81 0.191
chromatin organization GO:0006325 206 0.186
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.180
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.178
telomere capping GO:0016233 4 0.174
regulation of cellular amine metabolic process GO:0033238 20 0.169
regulation of neuron differentiation GO:0045664 281 0.167
modification dependent macromolecule catabolic process GO:0043632 133 0.160
cellular protein catabolic process GO:0044257 155 0.153
positive regulation of cellular amine metabolic process GO:0033240 5 0.149
production of molecular mediator of immune response GO:0002440 103 0.139
ubiquitin dependent protein catabolic process via the multivesicular body sorting pathway GO:0043162 3 0.128
regulation of actin filament length GO:0030832 45 0.123
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.119
regulation of cellular component biogenesis GO:0044087 181 0.114
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.114
regulation of homeostatic process GO:0032844 182 0.111
negative regulation of lymphocyte proliferation GO:0050672 45 0.110
regulation of cell projection organization GO:0031344 206 0.107
cytoplasmic transport GO:0016482 234 0.101
regulation of neuron projection development GO:0010975 169 0.098
negative regulation of intracellular signal transduction GO:1902532 167 0.096
lymphocyte mediated immunity GO:0002449 139 0.095
protein localization to organelle GO:0033365 185 0.095
chromatin modification GO:0016568 187 0.093
regulation of cellular ketone metabolic process GO:0010565 66 0.092
immunoglobulin production GO:0002377 73 0.092
negative regulation of leukocyte proliferation GO:0070664 46 0.090
b cell activation involved in immune response GO:0002312 50 0.088
somatic diversification of immune receptors GO:0002200 53 0.088
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.087
male gamete generation GO:0048232 285 0.087
negative regulation of molecular function GO:0044092 258 0.087
regulation of organelle organization GO:0033043 289 0.086
multicellular organism growth GO:0035264 161 0.086
regulation of cell activation GO:0050865 289 0.085
transmembrane transport GO:0055085 412 0.083
regulation of protein catabolic process GO:0042176 108 0.083
dna recombination GO:0006310 92 0.082
modification dependent protein catabolic process GO:0019941 133 0.082
negative regulation of cellular protein metabolic process GO:0032269 247 0.081
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.078
regulation of multi organism process GO:0043900 111 0.077
regulation of histone methylation GO:0031060 30 0.077
amine metabolic process GO:0009308 45 0.077
olfactory learning GO:0008355 2 0.076
negative regulation of cell proliferation GO:0008285 296 0.075
cellular ketone metabolic process GO:0042180 84 0.073
negative regulation of multi organism process GO:0043901 68 0.071
negative regulation of phosphorylation GO:0042326 166 0.070
histone methylation GO:0016571 71 0.070
ubiquitin dependent protein catabolic process GO:0006511 129 0.070
negative regulation of cellular component organization GO:0051129 194 0.069
regulation of cytoskeleton organization GO:0051493 122 0.068
regulation of tight junction assembly GO:2000810 2 0.068
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.067
cell activation involved in immune response GO:0002263 126 0.067
sodium ion transport GO:0006814 73 0.067
somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 51 0.067
small gtpase mediated signal transduction GO:0007264 97 0.066
defense response to other organism GO:0098542 197 0.065
positive regulation of protein complex assembly GO:0031334 45 0.063
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.062
ion transmembrane transport GO:0034220 361 0.061
lymphocyte activation involved in immune response GO:0002285 93 0.060
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.059
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 40 0.058
bmp signaling pathway GO:0030509 93 0.057
regulation of lymphocyte activation GO:0051249 240 0.057
regulation of alpha beta t cell activation GO:0046634 53 0.056
dna repair GO:0006281 107 0.056
positive regulation of nervous system development GO:0051962 221 0.055
cellular amino acid metabolic process GO:0006520 103 0.055
positive regulation of chromosome organization GO:2001252 33 0.055
t cell proliferation GO:0042098 120 0.054
negative regulation of phosphate metabolic process GO:0045936 184 0.054
regulation of defense response GO:0031347 233 0.054
spermatogenesis GO:0007283 284 0.053
proteasomal protein catabolic process GO:0010498 98 0.053
organic cyclic compound catabolic process GO:1901361 295 0.051
negative regulation of protein modification process GO:0031400 163 0.051
regulation of histone modification GO:0031056 56 0.050
muscle tissue development GO:0060537 308 0.050
somatic diversification of immunoglobulins involved in immune response GO:0002208 36 0.050
cilium morphogenesis GO:0060271 102 0.049
positive regulation of protein modification process GO:0031401 299 0.049
regulation of protein complex assembly GO:0043254 83 0.048
membrane organization GO:0061024 245 0.048
t cell anergy GO:0002870 4 0.048
regulation of protein modification by small protein conjugation or removal GO:1903320 57 0.048
t cell activation GO:0042110 289 0.047
rna interference GO:0016246 2 0.047
microtubule based process GO:0007017 236 0.047
somatic diversification of immunoglobulins GO:0016445 43 0.047
germ cell development GO:0007281 185 0.047
regionalization GO:0003002 337 0.047
somatic cell dna recombination GO:0016444 51 0.047
skeletal muscle organ development GO:0060538 163 0.046
isotype switching GO:0045190 36 0.046
positive regulation of t cell anergy GO:0002669 4 0.045
leukocyte proliferation GO:0070661 172 0.045
negative regulation of t cell activation GO:0050868 65 0.045
negative regulation of t cell proliferation GO:0042130 38 0.045
protein polymerization GO:0051258 57 0.044
dendrite development GO:0016358 115 0.044
camera type eye development GO:0043010 266 0.044
b cell mediated immunity GO:0019724 71 0.044
negative regulation of organelle organization GO:0010639 90 0.043
negative regulation of protein metabolic process GO:0051248 282 0.043
digestive tract development GO:0048565 190 0.043
negative regulation of blood pressure GO:0045776 22 0.042
regulation of actin polymerization or depolymerization GO:0008064 45 0.042
negative regulation of homeostatic process GO:0032845 71 0.042
b cell activation GO:0042113 161 0.042
aromatic compound catabolic process GO:0019439 286 0.041
actin polymerization or depolymerization GO:0008154 54 0.041
heterocycle catabolic process GO:0046700 280 0.041
regulation of t cell proliferation GO:0042129 92 0.040
microtubule cytoskeleton organization GO:0000226 157 0.040
somatic recombination of immunoglobulin genes involved in immune response GO:0002204 36 0.039
microtubule based transport GO:0010970 50 0.039
regulation of lymphocyte proliferation GO:0050670 117 0.039
negative regulation of synapse assembly GO:0051964 3 0.039
regulation of lymphocyte anergy GO:0002911 4 0.038
intracellular protein transport GO:0006886 204 0.038
regulation of t cell anergy GO:0002667 4 0.038
protein targeting GO:0006605 143 0.038
positive regulation of ion transmembrane transporter activity GO:0032414 15 0.037
regulation of chromosome organization GO:0033044 83 0.037
regulation of metal ion transport GO:0010959 106 0.036
posttranscriptional regulation of gene expression GO:0010608 155 0.036
sensory perception GO:0007600 245 0.035
immunoglobulin production involved in immunoglobulin mediated immune response GO:0002381 43 0.035
negative regulation of nervous system development GO:0051961 156 0.035
cellular nitrogen compound catabolic process GO:0044270 280 0.035
positive regulation of cell projection organization GO:0031346 95 0.035
regulation of leukocyte proliferation GO:0070663 121 0.035
negative regulation of immune system process GO:0002683 209 0.034
gene silencing GO:0016458 38 0.034
protein processing GO:0016485 163 0.034
regulation of t cell activation GO:0050863 170 0.034
blood vessel morphogenesis GO:0048514 285 0.034
regulation of transferase activity GO:0051338 263 0.033
defense response to virus GO:0051607 68 0.033
regulation of ion transmembrane transporter activity GO:0032412 54 0.033
methylation GO:0032259 134 0.033
ras protein signal transduction GO:0007265 77 0.033
negative regulation of lymphocyte activation GO:0051250 91 0.033
protein maturation GO:0051604 176 0.033
regulation of actin filament based process GO:0032970 99 0.032
telomere maintenance GO:0000723 19 0.032
positive regulation of ion transport GO:0043270 65 0.032
macromolecule methylation GO:0043414 120 0.031
rhythmic process GO:0048511 174 0.031
lymphocyte anergy GO:0002249 4 0.031
regulation of mapk cascade GO:0043408 248 0.031
translation GO:0006412 93 0.031
establishment of tissue polarity GO:0007164 28 0.030
anatomical structure homeostasis GO:0060249 145 0.030
lymphocyte proliferation GO:0046651 164 0.030
cytokine production GO:0001816 319 0.030
ribonucleotide metabolic process GO:0009259 291 0.030
gene silencing by rna GO:0031047 19 0.030
dendritic spine organization GO:0097061 26 0.030
actin filament polymerization GO:0030041 44 0.029
positive regulation of neuron projection development GO:0010976 79 0.029
neuromuscular process GO:0050905 99 0.029
regulation of chromatin modification GO:1903308 57 0.029
somatic recombination of immunoglobulin gene segments GO:0016447 42 0.029
jnk cascade GO:0007254 72 0.029
regulation of anatomical structure size GO:0090066 178 0.029
immunoglobulin mediated immune response GO:0016064 69 0.028
digestive system development GO:0055123 200 0.028
regulation of establishment of protein localization GO:0070201 181 0.028
cellular response to growth factor stimulus GO:0071363 197 0.027
organonitrogen compound catabolic process GO:1901565 264 0.027
purine nucleoside metabolic process GO:0042278 241 0.027
regulation of cation channel activity GO:2001257 22 0.027
positive regulation of ion transmembrane transport GO:0034767 24 0.027
response to growth factor GO:0070848 198 0.026
organelle assembly GO:0070925 177 0.026
positive regulation of lymphocyte anergy GO:0002913 4 0.026
mapk cascade GO:0000165 281 0.026
compound eye development GO:0048749 1 0.026
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.025
skin development GO:0043588 220 0.025
regulation of neuron death GO:1901214 134 0.025
autophagy GO:0006914 45 0.025
negative regulation of phosphorus metabolic process GO:0010563 184 0.025
regulation of transporter activity GO:0032409 57 0.025
regulation of ossification GO:0030278 112 0.025
cell type specific apoptotic process GO:0097285 268 0.025
regulation of bmp signaling pathway GO:0030510 60 0.025
positive regulation of protein catabolic process GO:0045732 60 0.025
negative regulation of cell development GO:0010721 169 0.024
negative regulation of mapk cascade GO:0043409 65 0.024
morphogenesis of embryonic epithelium GO:0016331 159 0.024
alpha beta t cell activation GO:0046631 91 0.024
posttranscriptional gene silencing by rna GO:0035194 10 0.024
microtubule based movement GO:0007018 84 0.024
engulfment of apoptotic cell GO:0043652 3 0.024
protein alkylation GO:0008213 81 0.024
cation transport GO:0006812 399 0.024
cilium assembly GO:0042384 81 0.024
synapse organization GO:0050808 125 0.023
negative regulation of cell activation GO:0050866 111 0.023
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.023
nucleobase containing small molecule metabolic process GO:0055086 352 0.023
regulation of translation GO:0006417 71 0.023
regulation of cytokine production GO:0001817 266 0.023
positive regulation of neuron differentiation GO:0045666 141 0.023
peptidyl serine phosphorylation GO:0018105 74 0.023
negative regulation of immune effector process GO:0002698 55 0.023
segmentation GO:0035282 93 0.023
positive regulation of histone modification GO:0031058 28 0.023
peptidyl amino acid modification GO:0018193 336 0.023
regulation of response to biotic stimulus GO:0002831 38 0.022
actin filament organization GO:0007015 113 0.022
cellular homeostasis GO:0019725 240 0.022
nucleoside monophosphate metabolic process GO:0009123 85 0.022
organelle localization GO:0051640 179 0.022
neuron apoptotic process GO:0051402 142 0.022
purine containing compound metabolic process GO:0072521 311 0.022
mrna processing GO:0006397 63 0.022
negative regulation of vascular endothelial growth factor receptor signaling pathway GO:0030948 6 0.022
maternal determination of anterior posterior axis embryo GO:0008358 2 0.022
apoptotic signaling pathway GO:0097190 306 0.022
nucleoside triphosphate metabolic process GO:0009141 230 0.022
regulation of cellular component size GO:0032535 121 0.021
positive regulation of chromatin modification GO:1903310 28 0.021
intracellular mrna localization GO:0008298 4 0.021
positive regulation of cellular catabolic process GO:0031331 148 0.021
positive regulation of cell development GO:0010720 237 0.021
regulation of cellular response to stress GO:0080135 159 0.021
positive regulation of growth GO:0045927 104 0.021
telencephalon development GO:0021537 186 0.021
transforming growth factor beta receptor signaling pathway GO:0007179 71 0.021
central nervous system neuron differentiation GO:0021953 162 0.021
purine ribonucleotide metabolic process GO:0009150 290 0.021
regulation of actin filament polymerization GO:0030833 38 0.021
ribonucleoside triphosphate metabolic process GO:0009199 220 0.020
trna wobble base modification GO:0002097 2 0.020
purine ribonucleotide catabolic process GO:0009154 208 0.020
regulation of cellular catabolic process GO:0031329 242 0.020
cell junction maintenance GO:0034331 4 0.020
cellular protein complex assembly GO:0043623 116 0.020
immune response regulating signaling pathway GO:0002764 125 0.020
regulation of ion transport GO:0043269 215 0.020
cellular hyperosmotic salinity response GO:0071475 0 0.020
forebrain development GO:0030900 302 0.020
regulation of protein localization GO:0032880 231 0.020
regulation of transmembrane transport GO:0034762 128 0.020
regulation of protein transport GO:0051223 163 0.019
ubiquitin dependent smad protein catabolic process GO:0030579 2 0.019
neuron death GO:0070997 154 0.019
glycosyl compound metabolic process GO:1901657 246 0.019
dorsal ventral axon guidance GO:0033563 3 0.019
innate immune response GO:0045087 157 0.019
nucleoside phosphate catabolic process GO:1901292 222 0.019
response to transforming growth factor beta GO:0071559 88 0.019
ossification GO:0001503 216 0.019
cellular response to hormone stimulus GO:0032870 150 0.019
organonitrogen compound biosynthetic process GO:1901566 192 0.019
ribonucleoside metabolic process GO:0009119 245 0.019
positive regulation of immune effector process GO:0002699 107 0.019
regulation of synapse assembly GO:0051963 29 0.018
negative regulation of alpha beta t cell activation GO:0046636 18 0.018
nucleoside phosphate metabolic process GO:0006753 338 0.018
positive regulation of defense response GO:0031349 124 0.018
dendritic spine development GO:0060996 30 0.018
regulation of kinase activity GO:0043549 249 0.018
immune response activating signal transduction GO:0002757 116 0.018
covalent chromatin modification GO:0016569 163 0.018
sequestering of metal ion GO:0051238 19 0.018
positive regulation of histone h3 k4 methylation GO:0051571 5 0.018
positive regulation of actin filament polymerization GO:0030838 26 0.018
regulation of chromatin organization GO:1902275 57 0.018
cell junction organization GO:0034330 77 0.018
purine nucleotide metabolic process GO:0006163 302 0.018
negative regulation of systemic arterial blood pressure GO:0003085 15 0.017
cell growth GO:0016049 130 0.017
cellular ion homeostasis GO:0006873 165 0.017
purine nucleoside catabolic process GO:0006152 205 0.017
social behavior GO:0035176 21 0.017
double strand break repair GO:0006302 48 0.017
nucleoside catabolic process GO:0009164 206 0.017
leukocyte differentiation GO:0002521 342 0.017
regulation of apoptotic signaling pathway GO:2001233 197 0.017
embryonic organ morphogenesis GO:0048562 276 0.017
embryonic placenta development GO:0001892 98 0.017
respiratory system development GO:0060541 190 0.016
adult behavior GO:0030534 135 0.016
negative regulation of bmp signaling pathway GO:0030514 35 0.016
rna processing GO:0006396 105 0.016
negative regulation of chromosome organization GO:2001251 30 0.016
regulation of protein targeting GO:1903533 61 0.016
epithelial cell proliferation GO:0050673 174 0.016
digestive tract morphogenesis GO:0048546 147 0.016
sequestering of calcium ion GO:0051208 18 0.016
endocytosis GO:0006897 168 0.016
regulation of sodium ion transport GO:0002028 29 0.016
developmental growth involved in morphogenesis GO:0060560 138 0.016
rho protein signal transduction GO:0007266 32 0.016
protein ubiquitination involved in ubiquitin dependent protein catabolic process GO:0042787 25 0.016
reactive oxygen species metabolic process GO:0072593 84 0.016
positive regulation of proteolysis GO:0045862 85 0.016
epidermis development GO:0008544 187 0.016
cell maturation GO:0048469 127 0.016
establishment of protein localization to organelle GO:0072594 118 0.016
positive regulation of production of molecular mediator of immune response GO:0002702 45 0.016
single organism nuclear import GO:1902593 95 0.016
spinal cord development GO:0021510 81 0.016
nuclear transport GO:0051169 139 0.016
leukocyte activation involved in immune response GO:0002366 126 0.015
ribose phosphate metabolic process GO:0019693 291 0.015
regulation of membrane potential GO:0042391 192 0.015
positive regulation of actin nucleation GO:0051127 3 0.015
positive regulation of histone methylation GO:0031062 16 0.015
positive regulation of gtp catabolic process GO:0033126 85 0.015
regulation of jnk cascade GO:0046328 62 0.015
positive regulation of cation channel activity GO:2001259 8 0.015
regulation of actin nucleation GO:0051125 4 0.015
peptidyl lysine modification GO:0018205 77 0.015
conditioned taste aversion GO:0001661 4 0.015
negative regulation of defense response GO:0031348 77 0.015
regulation of defense response to virus GO:0050688 18 0.015
response to insulin GO:0032868 100 0.015
mrna metabolic process GO:0016071 84 0.015
positive regulation of nucleoside metabolic process GO:0045979 91 0.015
positive regulation of nucleotide catabolic process GO:0030813 88 0.015
ribonucleoside triphosphate catabolic process GO:0009203 199 0.015
nucleotide catabolic process GO:0009166 217 0.015
negative regulation of apoptotic signaling pathway GO:2001234 104 0.015
oocyte anterior posterior axis specification GO:0007314 2 0.015
organophosphate catabolic process GO:0046434 232 0.015
blood circulation GO:0008015 195 0.015
establishment or maintenance of microtubule cytoskeleton polarity GO:0030951 1 0.015
cell division GO:0051301 120 0.015
protein deubiquitination GO:0016579 19 0.014
positive regulation of hydrolase activity GO:0051345 148 0.014
synaptic transmission GO:0007268 329 0.014
cytoskeleton dependent intracellular transport GO:0030705 50 0.014
positive regulation of nucleotide metabolic process GO:0045981 114 0.014
oocyte construction GO:0007308 2 0.014
protein localization to nucleus GO:0034504 121 0.014
positive regulation of cytoskeleton organization GO:0051495 49 0.014
maintenance of location GO:0051235 89 0.014
Worm
heart morphogenesis GO:0003007 178 0.014
negative regulation of cell morphogenesis involved in differentiation GO:0010771 48 0.014
carbohydrate derivative biosynthetic process GO:1901137 183 0.014
nucleocytoplasmic transport GO:0006913 139 0.014
sensory organ morphogenesis GO:0090596 242 0.014
purine nucleoside monophosphate metabolic process GO:0009126 81 0.014
ribonucleoside catabolic process GO:0042454 206 0.014
cellular response to organonitrogen compound GO:0071417 145 0.014
response to starvation GO:0042594 65 0.014
establishment or maintenance of cytoskeleton polarity GO:0030952 2 0.014
neural tube development GO:0021915 160 0.014
negative regulation of cellular response to growth factor stimulus GO:0090288 46 0.014
cognition GO:0050890 149 0.014
positive regulation of lymphocyte activation GO:0051251 140 0.014
cellular response to lipid GO:0071396 145 0.014
response to osmotic stress GO:0006970 21 0.014
ribonucleoside monophosphate metabolic process GO:0009161 80 0.014
striated muscle tissue development GO:0014706 293 0.014
response to organonitrogen compound GO:0010243 246 0.013
negative regulation of growth GO:0045926 99 0.013
gene silencing by mirna GO:0035195 10 0.013
lateral inhibition GO:0046331 1 0.013
glucose homeostasis GO:0042593 128 0.013
tight junction assembly GO:0070830 9 0.013
cilium movement GO:0003341 28 0.013
synaptic growth at neuromuscular junction GO:0051124 6 0.013
response to peptide GO:1901652 136 0.013
single organism cell adhesion GO:0098602 156 0.013
regulation of organ morphogenesis GO:2000027 144 0.013
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.013
establishment of organelle localization GO:0051656 122 0.013
sensory perception of mechanical stimulus GO:0050954 107 0.013
establishment or maintenance of cell polarity GO:0007163 86 0.013
neuron migration GO:0001764 122 0.013
negative regulation of neuron death GO:1901215 98 0.013
spermatid differentiation GO:0048515 115 0.013
protein oligomerization GO:0051259 67 0.013
chemotaxis GO:0006935 247 0.013
regulation of cellular response to growth factor stimulus GO:0090287 82 0.013
associative learning GO:0008306 61 0.013
regulation of b cell mediated immunity GO:0002712 37 0.013
epithelium migration GO:0090132 63 0.013
action potential GO:0001508 78 0.013
positive regulation of synaptic growth at neuromuscular junction GO:0045887 1 0.013
negative regulation of nf kappab transcription factor activity GO:0032088 15 0.013
carbohydrate homeostasis GO:0033500 128 0.013
neuron projection guidance GO:0097485 141 0.013
response to extracellular stimulus GO:0009991 127 0.013
regulation of epithelial cell proliferation GO:0050678 141 0.013
positive regulation of cell morphogenesis involved in differentiation GO:0010770 72 0.013
development of primary sexual characteristics GO:0045137 143 0.013
Worm
protein localization to membrane GO:0072657 108 0.013
regulation of protein ubiquitination GO:0031396 52 0.013
molting cycle GO:0042303 90 0.013
purine nucleotide catabolic process GO:0006195 211 0.013
establishment of protein localization to membrane GO:0090150 54 0.013
nitrogen compound transport GO:0071705 271 0.013
cellular component assembly involved in morphogenesis GO:0010927 139 0.013
symbiosis encompassing mutualism through parasitism GO:0044403 83 0.013
learning GO:0007612 98 0.013
internal protein amino acid acetylation GO:0006475 42 0.013
antimicrobial peptide production GO:0002775 2 0.013
atp metabolic process GO:0046034 75 0.013
positive regulation of cell activation GO:0050867 158 0.013
stress activated protein kinase signaling cascade GO:0031098 81 0.012
regulation of hydrolase activity GO:0051336 246 0.012
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 61 0.012
regulation of production of molecular mediator of immune response GO:0002700 65 0.012
microtubule severing GO:0051013 5 0.012
nucleoside metabolic process GO:0009116 246 0.012
positive regulation of dendritic spine morphogenesis GO:0061003 8 0.012
positive regulation of leukocyte mediated immunity GO:0002705 70 0.012
positive regulation of sodium ion transport GO:0010765 13 0.012
developmental maturation GO:0021700 193 0.012
regulation of leukocyte mediated immunity GO:0002703 104 0.012
positive regulation of intracellular estrogen receptor signaling pathway GO:0033148 4 0.012
dendritic spine morphogenesis GO:0060997 22 0.012
cellular response to acid chemical GO:0071229 68 0.012
cell fate commitment GO:0045165 210 0.012
regulation of proteolysis GO:0030162 164 0.012
regulation of proteasomal protein catabolic process GO:0061136 46 0.012
divalent inorganic cation transport GO:0072511 178 0.012
purine nucleoside triphosphate metabolic process GO:0009144 226 0.012
regulation of histone h3 k4 methylation GO:0051569 12 0.012
regulation of protein processing GO:0070613 96 0.012
intracellular receptor signaling pathway GO:0030522 74 0.012
phospholipid metabolic process GO:0006644 87 0.012
response to lipopolysaccharide GO:0032496 128 0.012
regulation of cell substrate adhesion GO:0010810 73 0.012
neuromuscular process controlling balance GO:0050885 59 0.012
positive regulation of cytokine production GO:0001819 174 0.012
positive regulation of homeostatic process GO:0032846 64 0.012
canonical wnt signaling pathway GO:0060070 130 0.012
regulation of microtubule polymerization or depolymerization GO:0031110 20 0.012
response to nutrient levels GO:0031667 109 0.012
placenta development GO:0001890 140 0.012
rna localization GO:0006403 23 0.012
intraciliary transport GO:0042073 9 0.012
g protein coupled receptor signaling pathway GO:0007186 243 0.012
regulation of reactive oxygen species metabolic process GO:2000377 40 0.012
respiratory tube development GO:0030323 167 0.012
positive regulation of innate immune response GO:0045089 80 0.012
regulation of cellular protein catabolic process GO:1903362 61 0.012
appendage development GO:0048736 166 0.011
response to acid chemical GO:0001101 111 0.011
protein monoubiquitination GO:0006513 11 0.011
protein modification by small protein removal GO:0070646 21 0.011
positive regulation of leukocyte differentiation GO:1902107 86 0.011
regulation of lymphocyte mediated immunity GO:0002706 84 0.011
regulation of synaptic plasticity GO:0048167 87 0.011
skeletal system development GO:0001501 356 0.011
purine ribonucleoside metabolic process GO:0046128 241 0.011
cellular response to nutrient levels GO:0031669 64 0.011
intrinsic apoptotic signaling pathway GO:0097193 132 0.011
learning or memory GO:0007611 148 0.011
cation transmembrane transport GO:0098655 266 0.011
regulation of protein deubiquitination GO:0090085 1 0.011
ameboidal type cell migration GO:0001667 128 0.011
trna wobble uridine modification GO:0002098 2 0.011
muscle cell differentiation GO:0042692 261 0.011
negative regulation of neuron differentiation GO:0045665 101 0.011
regulation of cytoplasmic transport GO:1903649 112 0.011
regulation of protein serine threonine kinase activity GO:0071900 157 0.011
regulation of protein localization to nucleus GO:1900180 60 0.011
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.011
histone lysine methylation GO:0034968 50 0.011
homeostasis of number of cells GO:0048872 210 0.011

Trp53bp1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.038
nervous system disease DOID:863 0 0.038
central nervous system disease DOID:331 0 0.019
brain disease DOID:936 0 0.012