Mus musculus

0 known processes

Spef1

sperm flagellar 1

(Aliases: Clamp,4931426K16Rik)

Spef1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of neuron differentiation GO:0045664 281 0.203
negative regulation of immune system process GO:0002683 209 0.154
homeostasis of number of cells GO:0048872 210 0.110
transmembrane transport GO:0055085 412 0.109
regionalization GO:0003002 337 0.099
lymphocyte differentiation GO:0030098 242 0.098
cation transport GO:0006812 399 0.089
cilium morphogenesis GO:0060271 102 0.078
negative regulation of nervous system development GO:0051961 156 0.074
embryonic organ morphogenesis GO:0048562 276 0.074
skin development GO:0043588 220 0.073
wound healing GO:0042060 157 0.070
cilium assembly GO:0042384 81 0.069
divalent metal ion transport GO:0070838 172 0.066
lateral inhibition GO:0046331 1 0.063
dendrite development GO:0016358 115 0.063
leukocyte differentiation GO:0002521 342 0.062
spinal cord development GO:0021510 81 0.057
organelle assembly GO:0070925 177 0.055
regulation of cell activation GO:0050865 289 0.054
regulation of leukocyte differentiation GO:1902105 159 0.051
t cell activation GO:0042110 289 0.049
cellular amino acid metabolic process GO:0006520 103 0.048
cell type specific apoptotic process GO:0097285 268 0.048
skeletal system morphogenesis GO:0048705 203 0.046
sensory perception GO:0007600 245 0.046
multicellular organismal homeostasis GO:0048871 164 0.045
cell adhesion GO:0007155 329 0.044
embryonic skeletal system development GO:0048706 120 0.044
ion transmembrane transport GO:0034220 361 0.044
small gtpase mediated signal transduction GO:0007264 97 0.043
developmental growth involved in morphogenesis GO:0060560 138 0.040
axonogenesis GO:0007409 274 0.038
g protein coupled receptor signaling pathway GO:0007186 243 0.038
regulation of cell migration GO:0030334 219 0.038
divalent inorganic cation transport GO:0072511 178 0.038
regulation of cellular ketone metabolic process GO:0010565 66 0.037
positive regulation of cell death GO:0010942 224 0.036
calcium ion transport GO:0006816 159 0.036
negative regulation of cell proliferation GO:0008285 296 0.036
positive regulation of neuron differentiation GO:0045666 141 0.036
extracellular structure organization GO:0043062 148 0.035
response to organic cyclic compound GO:0014070 198 0.035
regulation of cell motility GO:2000145 236 0.035
leukocyte homeostasis GO:0001776 79 0.034
rho protein signal transduction GO:0007266 32 0.034
synaptic transmission GO:0007268 329 0.034
male gamete generation GO:0048232 285 0.033
negative regulation of cell development GO:0010721 169 0.033
response to organonitrogen compound GO:0010243 246 0.033
epidermis development GO:0008544 187 0.032
regulation of lymphocyte activation GO:0051249 240 0.032
protein maturation GO:0051604 176 0.032
response to acid chemical GO:0001101 111 0.032
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.032
b cell activation GO:0042113 161 0.032
regulation of auditory receptor cell differentiation GO:0045607 4 0.032
inorganic ion transmembrane transport GO:0098660 234 0.031
microtubule based process GO:0007017 236 0.031
cation transmembrane transport GO:0098655 266 0.031
protein catabolic process GO:0030163 221 0.031
bmp signaling pathway GO:0030509 93 0.030
developmental maturation GO:0021700 193 0.029
positive regulation of homeostatic process GO:0032846 64 0.029
skeletal system development GO:0001501 356 0.029
regulation of neuron projection development GO:0010975 169 0.029
limb morphogenesis GO:0035108 149 0.028
negative regulation of protein metabolic process GO:0051248 282 0.028
spermatogenesis GO:0007283 284 0.028
epithelial cell development GO:0002064 159 0.028
negative regulation of cellular protein metabolic process GO:0032269 247 0.028
neural tube closure GO:0001843 90 0.028
forebrain development GO:0030900 302 0.028
renal system development GO:0072001 225 0.028
neuron migration GO:0001764 122 0.027
regulation of neural retina development GO:0061074 3 0.027
digestive tract development GO:0048565 190 0.027
gland development GO:0048732 330 0.027
central nervous system neuron differentiation GO:0021953 162 0.027
histone modification GO:0016570 159 0.026
regulation of organelle organization GO:0033043 289 0.026
macromolecule catabolic process GO:0009057 281 0.026
ear development GO:0043583 200 0.026
cellular ketone metabolic process GO:0042180 84 0.026
erythrocyte differentiation GO:0030218 88 0.026
blood circulation GO:0008015 195 0.026
connective tissue development GO:0061448 179 0.026
chemotaxis GO:0006935 247 0.026
regulation of retina development in camera type eye GO:1902866 3 0.025
regulation of cell cycle process GO:0010564 160 0.025
amine metabolic process GO:0009308 45 0.025
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.025
vagus nerve development GO:0021564 3 0.025
cellular amine metabolic process GO:0044106 44 0.025
regulation of cellular amino acid metabolic process GO:0006521 5 0.025
positive regulation of hydrolase activity GO:0051345 148 0.025
adaptive immune response GO:0002250 155 0.024
negative regulation of neuron differentiation GO:0045665 101 0.024
ras protein signal transduction GO:0007265 77 0.024
regulation of homeostatic process GO:0032844 182 0.023
hematopoietic progenitor cell differentiation GO:0002244 143 0.023
endochondral bone morphogenesis GO:0060350 50 0.023
limb development GO:0060173 166 0.023
cytokine production GO:0001816 319 0.023
negative regulation of molecular function GO:0044092 258 0.023
tissue homeostasis GO:0001894 115 0.023
mesodermal cell migration GO:0008078 4 0.023
protein oligomerization GO:0051259 67 0.023
sequestering of metal ion GO:0051238 19 0.022
digestive system development GO:0055123 200 0.022
regulation of striated muscle cell differentiation GO:0051153 81 0.022
negative regulation of intracellular signal transduction GO:1902532 167 0.022
myotube differentiation GO:0014902 105 0.022
determination of left right symmetry GO:0007368 80 0.022
regulation of ossification GO:0030278 112 0.022
microtubule cytoskeleton organization GO:0000226 157 0.021
regulation of lymphocyte differentiation GO:0045619 107 0.021
endocytosis GO:0006897 168 0.021
inorganic cation transmembrane transport GO:0098662 207 0.021
adult behavior GO:0030534 135 0.021
lymphocyte homeostasis GO:0002260 64 0.021
protein processing GO:0016485 163 0.021
positive regulation of organelle organization GO:0010638 128 0.021
calcium ion homeostasis GO:0055074 127 0.021
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.021
organic cyclic compound catabolic process GO:1901361 295 0.021
cell differentiation in spinal cord GO:0021515 53 0.020
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.020
circulatory system process GO:0003013 197 0.020
regulation of cellular amine metabolic process GO:0033238 20 0.020
dna metabolic process GO:0006259 303 0.020
regulation of myeloid cell differentiation GO:0045637 96 0.020
regulation of membrane potential GO:0042391 192 0.020
leukocyte migration GO:0050900 124 0.020
telencephalon development GO:0021537 186 0.020
mitochondrion organization GO:0007005 134 0.020
nucleotide metabolic process GO:0009117 332 0.020
positive regulation of nervous system development GO:0051962 221 0.020
hair cell differentiation GO:0035315 40 0.020
regulation of blood pressure GO:0008217 93 0.019
bundle of his development GO:0003166 4 0.019
muscle cell differentiation GO:0042692 261 0.019
regulation of myotube differentiation GO:0010830 62 0.019
microtubule based movement GO:0007018 84 0.019
sensory perception of mechanical stimulus GO:0050954 107 0.019
morphogenesis of embryonic epithelium GO:0016331 159 0.019
ribonucleoside triphosphate metabolic process GO:0009199 220 0.019
positive regulation of semaphorin plexin signaling pathway involved in outflow tract morphogenesis GO:2000764 1 0.019
single organism cell adhesion GO:0098602 156 0.019
myeloid cell homeostasis GO:0002262 114 0.019
single organismal cell cell adhesion GO:0016337 131 0.019
cell substrate adhesion GO:0031589 130 0.019
positive regulation of programmed cell death GO:0043068 218 0.019
sensory perception of sound GO:0007605 97 0.019
regulation of defense response GO:0031347 233 0.019
response to inorganic substance GO:0010035 96 0.019
response to oxygen levels GO:0070482 62 0.018
respiratory gaseous exchange GO:0007585 43 0.018
embryonic skeletal system morphogenesis GO:0048704 91 0.018
cellular response to acid chemical GO:0071229 68 0.018
regulation of binding GO:0051098 111 0.018
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 68 0.018
cellular response to organonitrogen compound GO:0071417 145 0.018
negative regulation of phosphate metabolic process GO:0045936 184 0.018
heart morphogenesis GO:0003007 178 0.018
actin cytoskeleton organization GO:0030036 220 0.018
negative regulation of cell activation GO:0050866 111 0.018
appendage morphogenesis GO:0035107 149 0.018
cardiocyte differentiation GO:0035051 87 0.018
covalent chromatin modification GO:0016569 163 0.018
skeletal muscle organ development GO:0060538 163 0.018
cell fate commitment GO:0045165 210 0.017
regulation of t cell activation GO:0050863 170 0.017
regulation of secretion by cell GO:1903530 249 0.017
sensory organ morphogenesis GO:0090596 242 0.017
t cell differentiation GO:0030217 174 0.017
neural retina development GO:0003407 41 0.017
cell maturation GO:0048469 127 0.017
intestinal epithelial structure maintenance GO:0060729 4 0.017
regulation of ras protein signal transduction GO:0046578 114 0.016
regulation of transferase activity GO:0051338 263 0.016
positive regulation of cell development GO:0010720 237 0.016
regulation of mapk cascade GO:0043408 248 0.016
intrinsic apoptotic signaling pathway GO:0097193 132 0.016
regulation of cell cycle GO:0051726 281 0.016
carbohydrate transport GO:0008643 62 0.016
myeloid leukocyte differentiation GO:0002573 119 0.016
tendon cell differentiation GO:0035990 4 0.016
sequestering of calcium ion GO:0051208 18 0.016
alpha beta t cell activation GO:0046631 91 0.016
organonitrogen compound biosynthetic process GO:1901566 192 0.016
regulation of protein catabolic process GO:0042176 108 0.016
muscle tissue development GO:0060537 308 0.016
positive regulation of immune effector process GO:0002699 107 0.016
protein acylation GO:0043543 64 0.016
cartilage development GO:0051216 140 0.016
chromatin modification GO:0016568 187 0.016
positive regulation of secondary heart field cardioblast proliferation GO:0072513 4 0.016
neuron maturation GO:0042551 29 0.016
mechanoreceptor differentiation GO:0042490 67 0.016
reactive oxygen species metabolic process GO:0072593 84 0.016
regulation of myeloid leukocyte differentiation GO:0002761 58 0.015
positive regulation of cellular amine metabolic process GO:0033240 5 0.015
skeletal muscle cell differentiation GO:0035914 66 0.015
forebrain generation of neurons GO:0021872 63 0.015
response to hypoxia GO:0001666 58 0.015
tumor necrosis factor superfamily cytokine production GO:0071706 51 0.015
positive regulation of myeloid cell differentiation GO:0045639 43 0.015
cellular response to hormone stimulus GO:0032870 150 0.015
protein modification by small protein conjugation or removal GO:0070647 207 0.015
compartment pattern specification GO:0007386 4 0.015
regulation of cellular component size GO:0032535 121 0.015
compound eye development GO:0048749 1 0.015
regulation of calcium ion transport GO:0051924 69 0.015
protein modification by small protein conjugation GO:0032446 187 0.015
face development GO:0060324 38 0.015
purine nucleoside triphosphate catabolic process GO:0009146 203 0.015
nucleobase containing small molecule metabolic process GO:0055086 352 0.015
divalent inorganic cation homeostasis GO:0072507 138 0.015
appendage development GO:0048736 166 0.015
cardiac right ventricle formation GO:0003219 3 0.015
circadian rhythm GO:0007623 114 0.015
epithelial tube formation GO:0072175 130 0.015
carbohydrate homeostasis GO:0033500 128 0.015
regulation of cell projection organization GO:0031344 206 0.015
innate immune response GO:0045087 157 0.014
regulation of ion transport GO:0043269 215 0.014
regulation of protein complex assembly GO:0043254 83 0.014
carbohydrate derivative biosynthetic process GO:1901137 183 0.014
organelle fission GO:0048285 170 0.014
respiratory system process GO:0003016 25 0.014
negative regulation of lymphocyte activation GO:0051250 91 0.014
auditory receptor cell differentiation GO:0042491 37 0.014
embryonic appendage morphogenesis GO:0035113 126 0.014
positive regulation of protein modification process GO:0031401 299 0.014
embryonic heart tube morphogenesis GO:0003143 51 0.014
regulation of proteolysis GO:0030162 164 0.014
cellular component assembly involved in morphogenesis GO:0010927 139 0.014
bone development GO:0060348 120 0.014
glossopharyngeal nerve morphogenesis GO:0021615 4 0.014
renal tubule development GO:0061326 87 0.014
immune effector process GO:0002252 321 0.014
rhythmic process GO:0048511 174 0.014
muscle system process GO:0003012 141 0.014
ribose phosphate metabolic process GO:0019693 291 0.014
positive regulation of cell morphogenesis involved in differentiation GO:0010770 72 0.014
negative regulation of phosphorus metabolic process GO:0010563 184 0.014
nuclear division GO:0000280 158 0.014
wnt signaling pathway GO:0016055 188 0.013
negative regulation of cellular amine metabolic process GO:0033239 1 0.013
bone morphogenesis GO:0060349 78 0.013
pallium development GO:0021543 120 0.013
autonomic nervous system development GO:0048483 43 0.013
protein alkylation GO:0008213 81 0.013
replacement ossification GO:0036075 26 0.013
regulation of epidermis development GO:0045682 33 0.013
b cell proliferation GO:0042100 53 0.013
positive regulation of endopeptidase activity GO:0010950 43 0.013
vagus nerve morphogenesis GO:0021644 2 0.013
alpha beta t cell differentiation GO:0046632 69 0.013
aortic valve morphogenesis GO:0003180 4 0.013
regulation of cytokine production GO:0001817 266 0.013
positive regulation of cell activation GO:0050867 158 0.013
regulation of neural precursor cell proliferation GO:2000177 70 0.013
striated muscle tissue development GO:0014706 293 0.013
left right pattern formation GO:0060972 23 0.013
columnar cuboidal epithelial cell differentiation GO:0002065 82 0.013
notch signaling pathway GO:0007219 71 0.013
peptide secretion GO:0002790 114 0.013
regulation of system process GO:0044057 200 0.013
cellular homeostasis GO:0019725 240 0.013
leukocyte proliferation GO:0070661 172 0.013
positive regulation of cell cycle process GO:0090068 61 0.013
membrane depolarization GO:0051899 64 0.013
syncytium formation GO:0006949 43 0.013
myeloid cell differentiation GO:0030099 233 0.013
ossification GO:0001503 216 0.013
negative regulation of protein modification process GO:0031400 163 0.013
cytoplasmic transport GO:0016482 234 0.013
regulation of nuclear division GO:0051783 56 0.013
pharynx development GO:0060465 1 0.013
lung development GO:0030324 164 0.012
positive regulation of lymphocyte mediated immunity GO:0002708 62 0.012
embryonic epithelial tube formation GO:0001838 130 0.012
determination of heart left right asymmetry GO:0061371 48 0.012
coagulation GO:0050817 78 0.012
neuron apoptotic process GO:0051402 142 0.012
negative regulation of neuron death GO:1901215 98 0.012
forebrain neuron differentiation GO:0021879 52 0.012
posttranscriptional regulation of gene expression GO:0010608 155 0.012
epithelial cell morphogenesis GO:0003382 41 0.012
multi organism behavior GO:0051705 62 0.012
interleukin 6 production GO:0032635 58 0.012
maintenance of location GO:0051235 89 0.012
regulation of chromosome organization GO:0033044 83 0.012
peripheral nervous system development GO:0007422 53 0.012
regulation of t cell differentiation GO:0045580 83 0.012
thymus development GO:0048538 41 0.012
positive regulation of transcription from rna polymerase ii promoter involved in myocardial precursor cell differentiation GO:0003257 3 0.012
positive regulation of leukocyte mediated immunity GO:0002705 70 0.012
macromolecule methylation GO:0043414 120 0.012
defense response to bacterium GO:0042742 119 0.012
response to oxidative stress GO:0006979 123 0.012
ribonucleoside metabolic process GO:0009119 245 0.012
organelle localization GO:0051640 179 0.012
purine containing compound metabolic process GO:0072521 311 0.012
regulation of metal ion transport GO:0010959 106 0.012
positive regulation of apoptotic process GO:0043065 217 0.012
endocardial cushion to mesenchymal transition involved in heart valve formation GO:0003199 4 0.012
mitochondrion distribution GO:0048311 4 0.012
leukocyte mediated immunity GO:0002443 174 0.012
rna processing GO:0006396 105 0.012
positive regulation of neuron projection development GO:0010976 79 0.012
organic hydroxy compound metabolic process GO:1901615 203 0.012
lymphocyte proliferation GO:0046651 164 0.012
regulation of chromatin modification GO:1903308 57 0.012
mitral valve development GO:0003174 4 0.012
glomerular mesangial cell development GO:0072144 3 0.012
reactive oxygen species biosynthetic process GO:1903409 8 0.012
activation of immune response GO:0002253 138 0.012
chromatin organization GO:0006325 206 0.012
neural precursor cell proliferation GO:0061351 121 0.012
cilium movement GO:0003341 28 0.011
spermatid development GO:0007286 108 0.011
cellular response to growth factor stimulus GO:0071363 197 0.011
positive regulation of lymphocyte activation GO:0051251 140 0.011
regulation of exit from mitosis GO:0007096 1 0.011
primary neural tube formation GO:0014020 95 0.011
spermatid differentiation GO:0048515 115 0.011
central nervous system neuron development GO:0021954 67 0.011
gliogenesis GO:0042063 141 0.011
positive regulation of ion transport GO:0043270 65 0.011
positive regulation of purine nucleotide catabolic process GO:0033123 88 0.011
aromatic compound catabolic process GO:0019439 286 0.011
nucleoside phosphate metabolic process GO:0006753 338 0.011
cardiac chamber morphogenesis GO:0003206 93 0.011
regulation of cell adhesion GO:0030155 154 0.011
regulation of reactive oxygen species metabolic process GO:2000377 40 0.011
mitotic cell cycle GO:0000278 195 0.011
monocarboxylic acid metabolic process GO:0032787 191 0.011
regulation of leukocyte proliferation GO:0070663 121 0.011
neural tube formation GO:0001841 108 0.011
inner ear morphogenesis GO:0042472 101 0.011
regulation of body fluid levels GO:0050878 162 0.011
positive regulation of t cell activation GO:0050870 101 0.011
regulation of actin filament based process GO:0032970 99 0.011
organophosphate catabolic process GO:0046434 232 0.011
regulation of vesicle mediated transport GO:0060627 139 0.011
midgut development GO:0007494 4 0.011
camera type eye development GO:0043010 266 0.011
positive regulation of gliogenesis GO:0014015 27 0.011
mitochondrial transport GO:0006839 36 0.011
extracellular matrix organization GO:0030198 147 0.011
nephron epithelium development GO:0072009 92 0.011
respiratory tube development GO:0030323 167 0.011
regulation of transmembrane transport GO:0034762 128 0.011
positive regulation of secretion GO:0051047 130 0.011
positive regulation of transcription from rna polymerase ii promoter involved in heart development GO:1901228 4 0.011
g1 s transition of mitotic cell cycle GO:0000082 57 0.011
cellular protein complex assembly GO:0043623 116 0.011
membrane organization GO:0061024 245 0.011
segmentation GO:0035282 93 0.011
mesenchyme development GO:0060485 152 0.011
ventral spinal cord development GO:0021517 48 0.011
regulation of neuron death GO:1901214 134 0.010
response to growth factor GO:0070848 198 0.010
immunoglobulin production GO:0002377 73 0.010
purine nucleoside catabolic process GO:0006152 205 0.010
regulation of cell division GO:0051302 76 0.010
ear morphogenesis GO:0042471 118 0.010
oxidation reduction process GO:0055114 342 0.010
protein secretion GO:0009306 111 0.010
artery development GO:0060840 53 0.010
regulation of erythrocyte differentiation GO:0045646 23 0.010
regulation of cysteine type endopeptidase activity GO:2000116 65 0.010
regulation of rho protein signal transduction GO:0035023 71 0.010
cellular nitrogen compound catabolic process GO:0044270 280 0.010
cell proliferation involved in outflow tract morphogenesis GO:0061325 4 0.010
positive regulation of cell cycle GO:0045787 92 0.010
regulation of kinase activity GO:0043549 249 0.010
cellular response to amino acid stimulus GO:0071230 29 0.010
neuron death GO:0070997 154 0.010
protein ubiquitination GO:0016567 171 0.010
glycoprotein metabolic process GO:0009100 116 0.010

Spef1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.029
disease of cellular proliferation DOID:14566 0 0.029
organ system cancer DOID:0050686 0 0.029
disease of anatomical entity DOID:7 0 0.021
musculoskeletal system disease DOID:17 0 0.021
nervous system disease DOID:863 0 0.016
sensory system disease DOID:0050155 0 0.012
eye and adnexa disease DOID:1492 0 0.010