Mus musculus

12 known processes

Pyhin1

pyrin and HIN domain family, member 1

(Aliases: 4930422C14,Ifix,Ifi209,AI447904,MGC130358,MGC130359)

Pyhin1 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
regulation of innate immune response GO:0045088 91 0.920
activation of innate immune response GO:0002218 56 0.919
leukocyte activation involved in immune response GO:0002366 126 0.869
defense response to other organism GO:0098542 197 0.862
activation of immune response GO:0002253 138 0.844
cell surface pattern recognition receptor signaling pathway GO:0002752 2 0.838
immune effector process GO:0002252 321 0.818
immune response activating signal transduction GO:0002757 116 0.793
positive regulation of defense response GO:0031349 124 0.785
immune response regulating signaling pathway GO:0002764 125 0.772
pattern recognition receptor signaling pathway GO:0002221 47 0.772
regulation of defense response GO:0031347 233 0.757
innate immune response activating signal transduction GO:0002758 50 0.729
immune response regulating cell surface receptor signaling pathway GO:0002768 80 0.698
positive regulation of innate immune response GO:0045089 80 0.682
cellular response to biotic stimulus GO:0071216 92 0.638
innate immune response GO:0045087 157 0.633
cytokine production GO:0001816 319 0.573
t cell activation GO:0042110 289 0.571
cellular response to lipopolysaccharide GO:0071222 77 0.526
immune response activating cell surface receptor signaling pathway GO:0002429 72 0.510
innate immune response activating cell surface receptor signaling pathway GO:0002220 4 0.493
response to molecule of fungal origin GO:0002238 4 0.492
response to molecule of bacterial origin GO:0002237 143 0.469
defense response to virus GO:0051607 68 0.462
detection of other organism GO:0098543 8 0.424
regulation of interferon beta production GO:0032648 13 0.423
regulation of lymphocyte proliferation GO:0050670 117 0.395
stimulatory c type lectin receptor signaling pathway GO:0002223 2 0.373
detection of fungus GO:0016046 2 0.369
regulation of multi organism process GO:0043900 111 0.368
reactive oxygen species metabolic process GO:0072593 84 0.352
regulation of cytokine production GO:0001817 266 0.351
toll like receptor 7 signaling pathway GO:0034154 4 0.328
cellular response to interferon alpha GO:0035457 4 0.313
Mouse
regulation of defense response to virus GO:0050688 18 0.295
leukocyte proliferation GO:0070661 172 0.286
symbiosis encompassing mutualism through parasitism GO:0044403 83 0.285
reactive oxygen species biosynthetic process GO:1903409 8 0.282
positive regulation of interferon alpha production GO:0032727 4 0.271
positive regulation of cytokine production GO:0001819 174 0.258
negative regulation of molecular function GO:0044092 258 0.254
Mouse
regulation of tumor necrosis factor production GO:0032680 49 0.248
cellular response to lipid GO:0071396 145 0.247
lymphocyte proliferation GO:0046651 164 0.243
negative regulation of immune system process GO:0002683 209 0.240
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.236
regulation of cell activation GO:0050865 289 0.234
interferon beta production GO:0032608 16 0.233
cellular response to cytokine stimulus GO:0071345 189 0.221
antigen receptor mediated signaling pathway GO:0050851 64 0.215
tumor necrosis factor superfamily cytokine production GO:0071706 51 0.213
regulation of interferon gamma production GO:0032649 57 0.208
viral process GO:0016032 41 0.206
ear development GO:0043583 200 0.206
Mouse
regulation of lymphocyte activation GO:0051249 240 0.205
regulation of tumor necrosis factor superfamily cytokine production GO:1903555 50 0.202
negative regulation of protein metabolic process GO:0051248 282 0.201
Mouse
tumor necrosis factor production GO:0032640 50 0.196
regulation of nlrp3 inflammasome complex assembly GO:1900225 4 0.195
t cell proliferation GO:0042098 120 0.195
t cell extravasation GO:0072683 4 0.191
mapk cascade GO:0000165 281 0.191
cell activation involved in immune response GO:0002263 126 0.191
positive regulation of interferon gamma production GO:0032729 39 0.182
type i interferon production GO:0032606 29 0.173
positive regulation of t cell receptor signaling pathway GO:0050862 4 0.173
natural killer cell mediated cytotoxicity GO:0042267 29 0.170
interferon gamma production GO:0032609 67 0.168
lipopolysaccharide mediated signaling pathway GO:0031663 25 0.165
negative regulation of multi organism process GO:0043901 68 0.163
regulation of hydrolase activity GO:0051336 246 0.163
Mouse
regulation of leukocyte proliferation GO:0070663 121 0.154
regulation of protein complex assembly GO:0043254 83 0.154
myeloid cell differentiation GO:0030099 233 0.154
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.151
positive regulation of immune effector process GO:0002699 107 0.149
cellular response to molecule of bacterial origin GO:0071219 83 0.148
positive regulation of immunological synapse formation GO:2000522 1 0.147
detection of biotic stimulus GO:0009595 10 0.147
reactive nitrogen species metabolic process GO:2001057 0 0.143
extrinsic apoptotic signaling pathway GO:0097191 126 0.138
regulation of natural killer cell mediated cytotoxicity GO:0042269 19 0.135
positive regulation of lymphocyte activation GO:0051251 140 0.134
natural killer cell activation GO:0030101 44 0.134
regulation of reactive oxygen species metabolic process GO:2000377 40 0.134
regulation of eosinophil degranulation GO:0043309 1 0.125
cellular response to molecule of fungal origin GO:0071226 2 0.125
regulation of leukocyte mediated immunity GO:0002703 104 0.124
cell killing GO:0001906 67 0.123
regulation of dendritic cell chemotaxis GO:2000508 1 0.122
negative regulation of toll like receptor signaling pathway GO:0034122 14 0.121
regulation of natural killer cell activation GO:0032814 22 0.116
toll like receptor signaling pathway GO:0002224 38 0.115
viral gene expression GO:0019080 3 0.115
regulation of protein localization GO:0032880 231 0.114
positive regulation of cd8 positive alpha beta t cell extravasation GO:2000451 2 0.113
small gtpase mediated signal transduction GO:0007264 97 0.109
organophosphate catabolic process GO:0046434 232 0.107
positive regulation of viral genome replication GO:0045070 2 0.105
negative regulation of cytokine production GO:0001818 84 0.104
jnk cascade GO:0007254 72 0.103
myeloid leukocyte differentiation GO:0002573 119 0.103
positive regulation of t cell extravasation GO:2000409 2 0.103
cellular response to interferon beta GO:0035458 21 0.102
cellular nitrogen compound catabolic process GO:0044270 280 0.101
positive regulation of leukocyte mediated cytotoxicity GO:0001912 31 0.101
regulation of cytokine biosynthetic process GO:0042035 59 0.101
negative regulation of viral genome replication GO:0045071 10 0.100
rho protein signal transduction GO:0007266 32 0.095
viral transcription GO:0019083 3 0.094
regulation of mapk cascade GO:0043408 248 0.093
interferon beta biosynthetic process GO:0045350 4 0.091
t cell receptor signaling pathway GO:0050852 46 0.090
purine containing compound catabolic process GO:0072523 213 0.089
apoptotic signaling pathway GO:0097190 306 0.089
positive regulation of mapk cascade GO:0043410 170 0.087
nitric oxide metabolic process GO:0046209 25 0.086
regulation of response to biotic stimulus GO:0002831 38 0.083
regulation of antigen receptor mediated signaling pathway GO:0050854 29 0.082
interleukin 1 production GO:0032612 31 0.080
response to lipopolysaccharide GO:0032496 128 0.080
regulation of t cell proliferation GO:0042129 92 0.080
regulation of t cell activation GO:0050863 170 0.079
negative regulation of protein processing GO:0010955 79 0.079
Mouse
ras protein signal transduction GO:0007265 77 0.079
membrane fusion GO:0061025 38 0.079
cytokine metabolic process GO:0042107 71 0.078
regulation of lymphocyte mediated immunity GO:0002706 84 0.077
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 52 0.075
negative regulation of hydrolase activity GO:0051346 71 0.075
Mouse
purine nucleoside triphosphate catabolic process GO:0009146 203 0.075
regulation of t cell costimulation GO:2000523 2 0.074
regulation of natural killer cell mediated immunity GO:0002715 19 0.074
positive regulation of tumor necrosis factor superfamily cytokine production GO:1903557 31 0.073
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.073
positive regulation of reactive oxygen species metabolic process GO:2000379 11 0.073
cd8 positive alpha beta t cell extravasation GO:0035697 3 0.072
regulation of establishment of protein localization GO:0070201 181 0.072
regulation of cysteine type endopeptidase activity GO:2000116 65 0.071
Mouse
regulation of cell killing GO:0031341 40 0.071
negative regulation of cysteine type endopeptidase activity GO:2000117 22 0.071
Mouse
positive regulation of osteoblast differentiation GO:0045669 34 0.070
Mouse
glycosyl compound catabolic process GO:1901658 206 0.068
lymphocyte mediated immunity GO:0002449 139 0.068
membrane organization GO:0061024 245 0.068
detection of external biotic stimulus GO:0098581 9 0.067
cytokine mediated signaling pathway GO:0019221 115 0.066
lymphocyte differentiation GO:0030098 242 0.066
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 62 0.065
Mouse
regulation of b cell activation GO:0050864 81 0.064
sequestering of calcium ion GO:0051208 18 0.063
production of molecular mediator of immune response GO:0002440 103 0.063
defense response to bacterium GO:0042742 119 0.063
regulation of t cell extravasation GO:2000407 3 0.062
negative regulation of proteolysis GO:0045861 74 0.062
Mouse
regulation of extrinsic apoptotic signaling pathway GO:2001236 77 0.060
positive regulation of stress activated mapk cascade GO:0032874 48 0.060
regulation of viral transcription GO:0046782 3 0.059
purine ribonucleoside metabolic process GO:0046128 241 0.059
regulation of immunological synapse formation GO:2000520 2 0.059
leukocyte mediated immunity GO:0002443 174 0.059
positive regulation of lymphocyte mediated immunity GO:0002708 62 0.059
cytokine biosynthetic process GO:0042089 68 0.059
natural killer cell mediated immunity GO:0002228 29 0.059
eosinophil activation GO:0043307 1 0.058
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 87 0.058
positive regulation by symbiont of host defense response GO:0052509 1 0.058
alpha beta t cell activation GO:0046631 91 0.058
heterocycle catabolic process GO:0046700 280 0.058
endocytosis GO:0006897 168 0.057
positive regulation of cytokine biosynthetic process GO:0042108 40 0.057
interspecies interaction between organisms GO:0044419 83 0.057
stress activated protein kinase signaling cascade GO:0031098 81 0.056
nitric oxide biosynthetic process GO:0006809 25 0.056
myeloid dendritic cell activation GO:0001773 25 0.056
regulation of nitric oxide biosynthetic process GO:0045428 18 0.054
viral life cycle GO:0019058 36 0.054
regulation of cd8 positive alpha beta t cell extravasation GO:2000449 3 0.054
t helper 17 cell chemotaxis GO:0035705 1 0.053
sequestering of metal ion GO:0051238 19 0.053
stress activated mapk cascade GO:0051403 80 0.052
positive regulation of hematopoietic stem cell migration GO:2000473 1 0.052
negative regulation of defense response GO:0031348 77 0.052
regulation of interleukin 2 production GO:0032663 28 0.051
regulation of cell motility GO:2000145 236 0.051
detection of bacterium GO:0016045 7 0.050
purine ribonucleotide catabolic process GO:0009154 208 0.049
regulation of cytoplasmic transport GO:1903649 112 0.048
positive regulation of secretion by cell GO:1903532 114 0.048
positive regulation of viral entry into host cell GO:0046598 3 0.048
regulation of actin nucleation GO:0051125 4 0.048
regulation of lipopolysaccharide mediated signaling pathway GO:0031664 9 0.047
t cell differentiation GO:0030217 174 0.047
cd4 positive alpha beta t cell differentiation involved in immune response GO:0002294 28 0.046
regulation of secretion GO:0051046 274 0.046
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.046
nucleotide metabolic process GO:0009117 332 0.046
microglial cell activation involved in immune response GO:0002282 1 0.045
positive regulation of cell activation GO:0050867 158 0.045
ribonucleoside triphosphate metabolic process GO:0009199 220 0.044
aromatic compound catabolic process GO:0019439 286 0.044
purine nucleoside catabolic process GO:0006152 205 0.043
glycosyl compound metabolic process GO:1901657 246 0.043
negative regulation of viral transcription GO:0032897 3 0.043
negative regulation of protein maturation GO:1903318 79 0.043
Mouse
eosinophil mediated immunity GO:0002447 1 0.042
regulation of purine nucleotide metabolic process GO:1900542 169 0.042
protein processing GO:0016485 163 0.042
Mouse
positive regulation of t cell costimulation GO:2000525 2 0.041
negative regulation of endopeptidase activity GO:0010951 44 0.041
Mouse
b cell activation involved in immune response GO:0002312 50 0.041
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.040
microglial cell activation GO:0001774 3 0.040
positive regulation of interleukin 18 production GO:0032741 2 0.040
nucleobase containing small molecule metabolic process GO:0055086 352 0.040
positive regulation of natural killer cell mediated cytotoxicity GO:0045954 16 0.040
positive regulation of lymphocyte proliferation GO:0050671 70 0.039
nucleoside triphosphate metabolic process GO:0009141 230 0.039
purine nucleoside metabolic process GO:0042278 241 0.039
nucleoside phosphate metabolic process GO:0006753 338 0.039
regulation of rho protein signal transduction GO:0035023 71 0.039
adaptive immune response GO:0002250 155 0.039
protein modification by small protein conjugation GO:0032446 187 0.039
purine ribonucleotide metabolic process GO:0009150 290 0.039
leukocyte differentiation GO:0002521 342 0.038
glial cell differentiation GO:0010001 131 0.038
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.038
chemokine production GO:0032602 34 0.038
neuronal action potential GO:0019228 54 0.038
carbohydrate derivative catabolic process GO:1901136 231 0.038
multicellular organismal signaling GO:0035637 91 0.038
cytoplasmic transport GO:0016482 234 0.038
g protein coupled receptor signaling pathway GO:0007186 243 0.038
glycoprotein biosynthetic process GO:0009101 89 0.037
positive regulation of glycoprotein biosynthetic process involved in immunological synapse formation GO:2000526 1 0.037
positive regulation of jnk cascade GO:0046330 46 0.037
regulation of cell migration GO:0030334 219 0.036
detection of bacterial lipoprotein GO:0042494 1 0.036
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 68 0.036
positive regulation of cellular amine metabolic process GO:0033240 5 0.036
regulation of secretion by cell GO:1903530 249 0.036
b cell activation GO:0042113 161 0.036
muscle cell differentiation GO:0042692 261 0.035
interleukin 6 production GO:0032635 58 0.035
signal transduction in absence of ligand GO:0038034 55 0.034
negative regulation of cellular amine metabolic process GO:0033239 1 0.034
organic cyclic compound catabolic process GO:1901361 295 0.034
calcium ion homeostasis GO:0055074 127 0.034
regulation of hematopoietic stem cell migration GO:2000471 1 0.034
chemokine mediated signaling pathway GO:0070098 17 0.033
cd8 positive alpha beta t cell proliferation GO:0035740 1 0.033
negative regulation of cellular component organization GO:0051129 194 0.033
regulation of ion homeostasis GO:2000021 64 0.033
interaction with host GO:0051701 22 0.032
positive regulation of interferon beta biosynthetic process GO:0045359 3 0.032
regulation of ras protein signal transduction GO:0046578 114 0.032
organonitrogen compound catabolic process GO:1901565 264 0.032
interleukin 1 beta production GO:0032611 30 0.031
negative regulation of cell proliferation GO:0008285 296 0.031
regulation of leukocyte mediated cytotoxicity GO:0001910 38 0.031
purine nucleoside triphosphate metabolic process GO:0009144 226 0.031
tumor necrosis factor biosynthetic process GO:0042533 10 0.031
detection of yeast GO:0001879 2 0.031
leukocyte mediated cytotoxicity GO:0001909 62 0.031
helper t cell chemotaxis GO:0035704 1 0.031
interleukin 12 secretion GO:0072610 3 0.030
viral genome replication GO:0019079 17 0.030
regulation of jnk cascade GO:0046328 62 0.030
regulation of defense response to virus by host GO:0050691 8 0.030
nucleoside phosphate catabolic process GO:1901292 222 0.030
eosinophil degranulation GO:0043308 1 0.030
ossification GO:0001503 216 0.030
Mouse
regulation of alpha beta t cell activation GO:0046634 53 0.030
cell recognition GO:0008037 83 0.030
cell adhesion GO:0007155 329 0.030
regulation of vesicle mediated transport GO:0060627 139 0.030
transmission of nerve impulse GO:0019226 76 0.030
positive regulation of multi organism process GO:0043902 26 0.030
regulation of proteolysis GO:0030162 164 0.030
Mouse
regulation of interferon beta biosynthetic process GO:0045357 4 0.029
nucleoside triphosphate catabolic process GO:0009143 205 0.029
positive regulation of dendritic cell chemotaxis GO:2000510 1 0.029
response to growth factor GO:0070848 198 0.029
immune complex clearance GO:0002434 2 0.029
response to type i interferon GO:0034340 12 0.029
nucleotide catabolic process GO:0009166 217 0.029
defense response to gram positive bacterium GO:0050830 50 0.029
negative regulation of peptidase activity GO:0010466 46 0.029
Mouse
hematopoietic stem cell migration GO:0035701 1 0.029
negative regulation of interleukin 6 production GO:0032715 17 0.029
regulation of cellular component biogenesis GO:0044087 181 0.029
purine containing compound metabolic process GO:0072521 311 0.028
nucleoside catabolic process GO:0009164 206 0.028
monocyte extravasation GO:0035696 2 0.028
regulation of homeostatic process GO:0032844 182 0.028
regulation of stress activated mapk cascade GO:0032872 69 0.028
negative regulation of cellular protein metabolic process GO:0032269 247 0.028
Mouse
i kappab kinase nf kappab signaling GO:0007249 85 0.028
purine nucleotide metabolic process GO:0006163 302 0.028
hematopoietic progenitor cell differentiation GO:0002244 143 0.028
epithelial tube morphogenesis GO:0060562 303 0.028
negative regulation of eosinophil degranulation GO:0043310 1 0.028
nucleocytoplasmic transport GO:0006913 139 0.027
regulation of interleukin 1 beta production GO:0032651 25 0.027
positive regulation of production of molecular mediator of immune response GO:0002702 45 0.027
positive regulation of tumor necrosis factor production GO:0032760 30 0.027
regulation of kinase activity GO:0043549 249 0.027
detection of molecule of bacterial origin GO:0032490 2 0.027
ribonucleoside catabolic process GO:0042454 206 0.027
negative regulation of nlrp3 inflammasome complex assembly GO:1900226 2 0.027
actin filament polymerization GO:0030041 44 0.027
purine nucleotide catabolic process GO:0006195 211 0.026
positive regulation of nucleotide binding oligomerization domain containing 2 signaling pathway GO:0070434 2 0.026
positive regulation of actin nucleation GO:0051127 3 0.026
negative regulation of immune effector process GO:0002698 55 0.026
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 55 0.026
positive regulation of t cell proliferation GO:0042102 52 0.026
positive regulation of hydrolase activity GO:0051345 148 0.026
positive regulation of kinase activity GO:0033674 155 0.026
cellular response to growth factor stimulus GO:0071363 197 0.026
positive regulation of t cell activation GO:0050870 101 0.026
negative regulation of leukocyte mediated immunity GO:0002704 29 0.026
exocytosis GO:0006887 121 0.026
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.026
anatomical structure homeostasis GO:0060249 145 0.026
alpha beta t cell proliferation GO:0046633 21 0.025
myd88 dependent toll like receptor signaling pathway GO:0002755 7 0.025
second messenger mediated signaling GO:0019932 73 0.025
single organismal cell cell adhesion GO:0016337 131 0.025
b cell proliferation GO:0042100 53 0.025
ribonucleoside triphosphate catabolic process GO:0009203 199 0.025
actin polymerization or depolymerization GO:0008154 54 0.025
positive regulation of cell migration GO:0030335 109 0.025
positive regulation of secretion GO:0051047 130 0.024
cytokine secretion GO:0050663 72 0.024
positive regulation of monocyte extravasation GO:2000439 1 0.024
negative regulation of ripoptosome assembly involved in necroptotic process GO:1902443 3 0.024
positive regulation of rac gtpase activity GO:0032855 14 0.024
negative regulation of intracellular signal transduction GO:1902532 167 0.023
germ cell development GO:0007281 185 0.023
cd4 positive alpha beta t cell differentiation GO:0043367 41 0.023
regulation of type 2 immune response GO:0002828 18 0.023
purine ribonucleoside catabolic process GO:0046130 205 0.023
ribonucleotide metabolic process GO:0009259 291 0.023
vesicle organization GO:0016050 60 0.023
positive regulation of nucleotide catabolic process GO:0030813 88 0.023
regulation of protein processing GO:0070613 96 0.023
Mouse
peptidyl amino acid modification GO:0018193 336 0.023
regulation of interleukin 12 production GO:0032655 30 0.023
ensheathment of neurons GO:0007272 76 0.023
cellular divalent inorganic cation homeostasis GO:0072503 127 0.023
regulation of monocyte extravasation GO:2000437 2 0.022
interleukin 18 production GO:0032621 4 0.022
positive regulation of platelet activation GO:0010572 5 0.022
ameboidal type cell migration GO:0001667 128 0.022
carbohydrate derivative biosynthetic process GO:1901137 183 0.022
regulation of production of molecular mediator of immune response GO:0002700 65 0.022
positive regulation of apoptotic process GO:0043065 217 0.022
regulation of apoptotic signaling pathway GO:2001233 197 0.022
morphogenesis of a branching structure GO:0001763 203 0.022
negative regulation of cell development GO:0010721 169 0.022
positive regulation of natural killer cell mediated immunity GO:0002717 16 0.022
eosinophil activation involved in immune response GO:0002278 1 0.022
protein kinase b signaling GO:0043491 74 0.022
cation transport GO:0006812 399 0.022
positive regulation of leukocyte proliferation GO:0070665 73 0.022
cellular amine metabolic process GO:0044106 44 0.022
positive regulation of nitric oxide biosynthetic process GO:0045429 14 0.021
protein maturation GO:0051604 176 0.021
Mouse
regulation of gtp catabolic process GO:0033124 113 0.021
regulation of cellular ketone metabolic process GO:0010565 66 0.021
forebrain development GO:0030900 302 0.021
regulation of cell cycle process GO:0010564 160 0.021
regulation of vesicle fusion GO:0031338 6 0.021
regulation of cellular catabolic process GO:0031329 242 0.021
plasma membrane organization GO:0007009 90 0.021
regulation of organelle organization GO:0033043 289 0.021
negative regulation of reactive oxygen species metabolic process GO:2000378 10 0.021
stem cell differentiation GO:0048863 268 0.021
regulation of ossification GO:0030278 112 0.021
Mouse
negative regulation of synapse assembly GO:0051964 3 0.021
protein localization to membrane GO:0072657 108 0.021
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.021
positive regulation of cellular catabolic process GO:0031331 148 0.021
t cell differentiation involved in immune response GO:0002292 30 0.020
positive regulation of inflammatory response to antigenic stimulus GO:0002863 11 0.020
positive regulation of regulatory t cell differentiation GO:0045591 4 0.020
intracellular protein transport GO:0006886 204 0.020
platelet morphogenesis GO:0036344 13 0.020
regulation of nucleoside metabolic process GO:0009118 130 0.020
defense response to protozoan GO:0042832 25 0.020
regulation of nucleotide catabolic process GO:0030811 122 0.020
negative regulation of nervous system development GO:0051961 156 0.020
regulation of peptidase activity GO:0052547 96 0.020
Mouse
negative regulation of phosphate metabolic process GO:0045936 184 0.020
positive regulation of type i interferon mediated signaling pathway GO:0060340 4 0.020
regulation of protein maturation GO:1903317 96 0.020
Mouse
positive regulation of cell killing GO:0031343 33 0.020
protein secretion GO:0009306 111 0.019
positive regulation of leukocyte mediated immunity GO:0002705 70 0.019
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.019
negative regulation of viral entry into host cell GO:0046597 10 0.019
wound healing GO:0042060 157 0.019
regulation of toll like receptor signaling pathway GO:0034121 20 0.019
regulation of cd8 positive alpha beta t cell proliferation GO:2000564 1 0.019
carbohydrate metabolic process GO:0005975 230 0.019
cellular protein complex assembly GO:0043623 116 0.019
negative regulation of macrophage apoptotic process GO:2000110 3 0.019
myeloid leukocyte activation GO:0002274 83 0.019
immune complex clearance by monocytes and macrophages GO:0002436 2 0.019
cytoplasmic pattern recognition receptor signaling pathway GO:0002753 10 0.019
cd4 positive alpha beta t cell activation GO:0035710 45 0.019
negative regulation of cell cycle GO:0045786 123 0.019
phagocytosis GO:0006909 66 0.018
positive t cell selection GO:0043368 23 0.018
positive regulation of chemokine production GO:0032722 22 0.018
positive regulation of ras gtpase activity GO:0032320 65 0.018
regulation of binding GO:0051098 111 0.018
peptide transport GO:0015833 133 0.018
guanosine containing compound catabolic process GO:1901069 144 0.018
regulation of rho gtpase activity GO:0032319 58 0.018
cellular amino acid metabolic process GO:0006520 103 0.018
negative regulation of phosphorus metabolic process GO:0010563 184 0.018
positive regulation of alpha beta t cell activation GO:0046635 39 0.018
neuron migration GO:0001764 122 0.017
negative regulation of binding GO:0051100 39 0.017
regulation of protein secretion GO:0050708 82 0.017
maintenance of location GO:0051235 89 0.017
modification by symbiont of host morphology or physiology GO:0044003 4 0.017
protein localization to organelle GO:0033365 185 0.017
negative regulation of homeostatic process GO:0032845 71 0.017
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.017
neutrophil migration GO:1990266 37 0.017
positive regulation of gtpase activity GO:0043547 85 0.017
nuclear import GO:0051170 95 0.017
erk1 and erk2 cascade GO:0070371 77 0.017
organelle fusion GO:0048284 28 0.017
regulation of interleukin 1 production GO:0032652 26 0.017
regulation of interleukin 6 production GO:0032675 55 0.017
detection of chemical stimulus involved in sensory perception of smell GO:0050911 4 0.017
regulation of actin filament polymerization GO:0030833 38 0.017
negative regulation of viral process GO:0048525 23 0.017
response to hyperoxia GO:0055093 2 0.017
induction by organism of immune response of other organism involved in symbiotic interaction GO:0052558 1 0.016
interleukin 2 production GO:0032623 33 0.016
positive regulation of interleukin 12 production GO:0032735 21 0.016
microglia development GO:0014005 2 0.016
divalent metal ion transport GO:0070838 172 0.016
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 40 0.016
posttranscriptional regulation of gene expression GO:0010608 155 0.016
myeloid cell homeostasis GO:0002262 114 0.016
positive regulation of protein secretion GO:0050714 52 0.016
antimicrobial peptide biosynthetic process GO:0002777 2 0.016
endomembrane system organization GO:0010256 147 0.016
positive regulation of apoptotic signaling pathway GO:2001235 95 0.016
modulation by organism of defense response of other organism involved in symbiotic interaction GO:0052255 1 0.016
natural killer cell proliferation GO:0001787 3 0.016
regulation of immune complex clearance by monocytes and macrophages GO:0090264 2 0.016
response to defense related host nitric oxide production GO:0052565 2 0.016
regulation of cell cycle GO:0051726 281 0.016
regulation of exocytosis GO:0017157 61 0.016
ribonucleotide catabolic process GO:0009261 208 0.016
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 45 0.016
homeostasis of number of cells GO:0048872 210 0.016
cellular ketone metabolic process GO:0042180 84 0.016
response to interferon gamma GO:0034341 34 0.016
t cell activation involved in immune response GO:0002286 43 0.016
positive regulation of leukocyte differentiation GO:1902107 86 0.016
positive regulation of monocyte chemotaxis GO:0090026 2 0.016
cellular protein catabolic process GO:0044257 155 0.015
cerebral cortex development GO:0021987 86 0.015
protein targeting GO:0006605 143 0.015
cellular response to organic cyclic compound GO:0071407 87 0.015
cellular homeostasis GO:0019725 240 0.015
oligodendrocyte differentiation GO:0048709 53 0.015
dna damage response signal transduction by p53 class mediator resulting in transcription of p21 class mediator GO:0006978 2 0.015
regulation of antimicrobial humoral response GO:0002759 3 0.015
ribose phosphate metabolic process GO:0019693 291 0.015
response to host immune response GO:0052572 3 0.015
positive regulation of ossification GO:0045778 47 0.015
Mouse
positive regulation of endocytosis GO:0045807 42 0.015
regulation of nucleotide metabolic process GO:0006140 169 0.015
negative regulation of innate immune response GO:0045824 17 0.015
negative regulation of lymphocyte activation GO:0051250 91 0.015
positive regulation of purine nucleotide catabolic process GO:0033123 88 0.015
blood vessel morphogenesis GO:0048514 285 0.015
regulation of myeloid cell differentiation GO:0045637 96 0.015
positive regulation of lipopolysaccharide mediated signaling pathway GO:0031666 5 0.015
protein polyubiquitination GO:0000209 33 0.015
amine metabolic process GO:0009308 45 0.015
positive regulation of nf kappab transcription factor activity GO:0051092 30 0.015
regulation of type i interferon production GO:0032479 22 0.015
mitotic cell cycle process GO:1903047 159 0.015
positive regulation of response to wounding GO:1903036 66 0.014
positive regulation of interferon alpha biosynthetic process GO:0045356 1 0.014
nitrogen compound transport GO:0071705 271 0.014
regulation of cytokine production involved in immune response GO:0002718 26 0.014

Pyhin1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org