Mus musculus

17 known processes

Defa24

defensin, alpha, 24

(Aliases: Defcr24)

Defa24 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
defense response to bacterium GO:0042742 119 0.102
antibacterial humoral response GO:0019731 8 0.101
transmembrane transport GO:0055085 412 0.096
cellular amine metabolic process GO:0044106 44 0.092
cation transport GO:0006812 399 0.086
defense response to other organism GO:0098542 197 0.085
cellular response to lipopolysaccharide GO:0071222 77 0.081
Mouse
ion transmembrane transport GO:0034220 361 0.076
response to lipopolysaccharide GO:0032496 128 0.074
Mouse
cellular amino acid metabolic process GO:0006520 103 0.074
defense response to gram negative bacterium GO:0050829 28 0.071
Mouse
response to molecule of bacterial origin GO:0002237 143 0.070
Mouse
regulation of cellular amine metabolic process GO:0033238 20 0.066
cation transmembrane transport GO:0098655 266 0.063
innate immune response GO:0045087 157 0.059
Human
oxidation reduction process GO:0055114 342 0.056
amine metabolic process GO:0009308 45 0.052
regulation of cellular ketone metabolic process GO:0010565 66 0.051
positive regulation of cellular amine metabolic process GO:0033240 5 0.047
humoral immune response GO:0006959 57 0.047
regulation of feeding behavior GO:0060259 3 0.046
cellular alcohol biosynthetic process GO:0044108 3 0.044
short chain fatty acid catabolic process GO:0019626 2 0.041
calcitriol biosynthetic process from calciol GO:0036378 3 0.041
carbohydrate metabolic process GO:0005975 230 0.039
cellular response to biotic stimulus GO:0071216 92 0.039
Mouse
male gamete generation GO:0048232 285 0.039
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.038
small molecule biosynthetic process GO:0044283 132 0.038
regulation of cellular amino acid metabolic process GO:0006521 5 0.038
nitrogen compound transport GO:0071705 271 0.037
peptidyl amino acid modification GO:0018193 336 0.036
fat soluble vitamin biosynthetic process GO:0042362 4 0.035
cellular response to molecule of bacterial origin GO:0071219 83 0.035
Mouse
immune effector process GO:0002252 321 0.034
cellular alcohol metabolic process GO:0044107 3 0.034
macromolecule catabolic process GO:0009057 281 0.034
cellular response to lipid GO:0071396 145 0.033
Mouse
inorganic ion transmembrane transport GO:0098660 234 0.033
spermatogenesis GO:0007283 284 0.032
vitamin d3 metabolic process GO:0070640 3 0.032
regulation of defense response GO:0031347 233 0.032
cytokine production GO:0001816 319 0.032
sulfur compound metabolic process GO:0006790 100 0.032
cellular ketone metabolic process GO:0042180 84 0.031
cellular response to organonitrogen compound GO:0071417 145 0.031
cellular lipid metabolic process GO:0044255 323 0.031
organonitrogen compound catabolic process GO:1901565 264 0.030
inorganic cation transmembrane transport GO:0098662 207 0.030
protein catabolic process GO:0030163 221 0.030
response to organonitrogen compound GO:0010243 246 0.029
apoptotic signaling pathway GO:0097190 306 0.029
vitamin d biosynthetic process GO:0042368 3 0.028
negative regulation of immune system process GO:0002683 209 0.027
regulation of hydrolase activity GO:0051336 246 0.027
secondary alcohol metabolic process GO:1902652 3 0.027
wnt signaling pathway GO:0016055 188 0.027
fatty acid metabolic process GO:0006631 121 0.027
posttranscriptional regulation of gene expression GO:0010608 155 0.026
regulation of membrane potential GO:0042391 192 0.026
regulation of peptidase activity GO:0052547 96 0.026
cellular response to dna damage stimulus GO:0006974 207 0.026
cell type specific apoptotic process GO:0097285 268 0.026
alcohol metabolic process GO:0006066 116 0.026
negative regulation of protein metabolic process GO:0051248 282 0.026
lipid biosynthetic process GO:0008610 179 0.025
protein maturation GO:0051604 176 0.025
locomotory behavior GO:0007626 195 0.025
organonitrogen compound biosynthetic process GO:1901566 192 0.024
small gtpase mediated signal transduction GO:0007264 97 0.024
regulation of protein localization GO:0032880 231 0.024
hematopoietic progenitor cell differentiation GO:0002244 143 0.024
nucleobase containing small molecule metabolic process GO:0055086 352 0.024
carbohydrate derivative biosynthetic process GO:1901137 183 0.024
negative regulation of cellular protein metabolic process GO:0032269 247 0.024
cellular nitrogen compound catabolic process GO:0044270 280 0.023
protein processing GO:0016485 163 0.023
regulation of cellular component biogenesis GO:0044087 181 0.023
defense response to gram positive bacterium GO:0050830 50 0.023
Mouse
regulation of lymphocyte activation GO:0051249 240 0.023
glycoprotein metabolic process GO:0009100 116 0.022
cellular homeostasis GO:0019725 240 0.022
monocarboxylic acid metabolic process GO:0032787 191 0.022
muscle cell differentiation GO:0042692 261 0.022
anion transport GO:0006820 177 0.022
ras protein signal transduction GO:0007265 77 0.021
glycoprotein biosynthetic process GO:0009101 89 0.021
regulation of cell cycle GO:0051726 281 0.021
negative regulation of cell proliferation GO:0008285 296 0.020
response to organic cyclic compound GO:0014070 198 0.020
skin development GO:0043588 220 0.020
regulation of cell activation GO:0050865 289 0.020
epithelial cell development GO:0002064 159 0.020
organic anion transport GO:0015711 137 0.020
regulation of angiotensin metabolic process GO:0060177 4 0.019
regulation of protein transport GO:0051223 163 0.019
purine nucleotide metabolic process GO:0006163 302 0.019
mitotic cell cycle GO:0000278 195 0.019
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.019
cell adhesion GO:0007155 329 0.019
regulation of establishment of protein localization GO:0070201 181 0.019
negative regulation of molecular function GO:0044092 258 0.019
divalent inorganic cation transport GO:0072511 178 0.019
organic hydroxy compound metabolic process GO:1901615 203 0.019
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.019
cellular protein complex assembly GO:0043623 116 0.019
t cell activation GO:0042110 289 0.018
regulation of anatomical structure size GO:0090066 178 0.018
regulation of cellular catabolic process GO:0031329 242 0.018
negative regulation of cellular amine metabolic process GO:0033239 1 0.018
nucleoside triphosphate metabolic process GO:0009141 230 0.018
regulation of cytokine production GO:0001817 266 0.018
maintenance of location GO:0051235 89 0.018
negative regulation of hydrolase activity GO:0051346 71 0.018
heterocycle catabolic process GO:0046700 280 0.018
response to growth factor GO:0070848 198 0.018
regulation of proteolysis GO:0030162 164 0.018
membrane organization GO:0061024 245 0.017
regulation of blood pressure GO:0008217 93 0.017
nucleotide metabolic process GO:0009117 332 0.017
cellular response to hormone stimulus GO:0032870 150 0.017
cellular response to cytokine stimulus GO:0071345 189 0.017
ribonucleoside metabolic process GO:0009119 245 0.017
mesodermal cell migration GO:0008078 4 0.017
regulation of cell cycle process GO:0010564 160 0.017
regulation of protein kinase activity GO:0045859 232 0.017
regulation of hormone levels GO:0010817 211 0.017
cellular ion homeostasis GO:0006873 165 0.017
cell activation involved in immune response GO:0002263 126 0.017
camera type eye development GO:0043010 266 0.016
epithelial cell proliferation GO:0050673 174 0.016
regulation of angiotensin levels in blood GO:0002002 4 0.016
organelle fission GO:0048285 170 0.016
multicellular organismal signaling GO:0035637 91 0.016
purine containing compound metabolic process GO:0072521 311 0.016
sequestering of calcium ion GO:0051208 18 0.016
regulation of transferase activity GO:0051338 263 0.016
regulation of transmembrane transport GO:0034762 128 0.016
aromatic compound catabolic process GO:0019439 286 0.016
positive regulation of protein modification process GO:0031401 299 0.016
muscle tissue development GO:0060537 308 0.016
fat cell differentiation GO:0045444 160 0.016
response to oxygen levels GO:0070482 62 0.016
response to drug GO:0042493 75 0.016
Mouse
mapk cascade GO:0000165 281 0.016
regulation of response to wounding GO:1903034 189 0.016
regulation of wnt signaling pathway GO:0030111 123 0.016
activation of immune response GO:0002253 138 0.015
multicellular organism growth GO:0035264 161 0.015
muscle adaptation GO:0043500 39 0.015
organic cyclic compound catabolic process GO:1901361 295 0.015
carboxylic acid biosynthetic process GO:0046394 86 0.015
glycosylation GO:0070085 62 0.015
nucleoside metabolic process GO:0009116 246 0.015
regulation of ion transport GO:0043269 215 0.015
protein modification by small protein conjugation or removal GO:0070647 207 0.015
regulation of secretion by cell GO:1903530 249 0.015
calcium ion transport GO:0006816 159 0.015
regulation of circadian sleep wake cycle GO:0042749 3 0.015
organic hydroxy compound biosynthetic process GO:1901617 77 0.015
myotube differentiation GO:0014902 105 0.015
macromolecule glycosylation GO:0043413 55 0.015
germ cell development GO:0007281 185 0.015
purine ribonucleotide metabolic process GO:0009150 290 0.015
circulatory system process GO:0003013 197 0.015
regulation of mapk cascade GO:0043408 248 0.015
regulation of kinase activity GO:0043549 249 0.015
glycosyl compound metabolic process GO:1901657 246 0.015
positive regulation of protein phosphorylation GO:0001934 242 0.015
sensory perception GO:0007600 245 0.015
lipid localization GO:0010876 126 0.014
skeletal muscle organ development GO:0060538 163 0.014
response to nutrient levels GO:0031667 109 0.014
protein glycosylation GO:0006486 55 0.014
purine nucleoside catabolic process GO:0006152 205 0.014
regulation of defense response to bacterium GO:1900424 3 0.014
nucleotide catabolic process GO:0009166 217 0.014
bone development GO:0060348 120 0.014
steroid metabolic process GO:0008202 119 0.014
lymphocyte proliferation GO:0046651 164 0.014
compound eye development GO:0048749 1 0.014
multi multicellular organism process GO:0044706 109 0.014
epidermis development GO:0008544 187 0.014
adaptive immune response GO:0002250 155 0.014
protein modification by small protein conjugation GO:0032446 187 0.014
naphthalene metabolic process GO:0018931 1 0.014
inorganic anion transport GO:0015698 43 0.014
ribonucleotide metabolic process GO:0009259 291 0.014
reactive oxygen species metabolic process GO:0072593 84 0.014
sodium ion transport GO:0006814 73 0.014
ribonucleotide catabolic process GO:0009261 208 0.014
regulation of mitotic cell cycle GO:0007346 126 0.014
gland development GO:0048732 330 0.014
spermatid differentiation GO:0048515 115 0.014
cellular chemical homeostasis GO:0055082 215 0.014
peptide transport GO:0015833 133 0.014
regulation of inflammatory response GO:0050727 147 0.014
blood circulation GO:0008015 195 0.014
establishment of blood nerve barrier GO:0008065 3 0.014
naphthalene containing compound metabolic process GO:0090420 1 0.014
purine nucleoside metabolic process GO:0042278 241 0.014
leukocyte differentiation GO:0002521 342 0.014
regulation of organelle organization GO:0033043 289 0.014
modification dependent macromolecule catabolic process GO:0043632 133 0.014
regulation of protein catabolic process GO:0042176 108 0.014
regulation of protein secretion GO:0050708 82 0.013
leukocyte activation involved in immune response GO:0002366 126 0.013
organic acid biosynthetic process GO:0016053 86 0.013
nucleoside phosphate metabolic process GO:0006753 338 0.013
response to decreased oxygen levels GO:0036293 59 0.013
positive regulation of cytokine production GO:0001819 174 0.013
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.013
organophosphate catabolic process GO:0046434 232 0.013
ubiquitin dependent protein catabolic process GO:0006511 129 0.013
purine ribonucleoside metabolic process GO:0046128 241 0.013
positive regulation of lymphocyte activation GO:0051251 140 0.013
rho protein signal transduction GO:0007266 32 0.013
regulation of endopeptidase activity GO:0052548 89 0.013
negative regulation of protein phosphorylation GO:0001933 126 0.013
negative regulation of phosphate metabolic process GO:0045936 184 0.013
response to peptide hormone GO:0043434 127 0.013
negative regulation of intracellular signal transduction GO:1902532 167 0.013
negative regulation of proteolysis GO:0045861 74 0.013
response to inorganic substance GO:0010035 96 0.013
negative regulation of phosphorus metabolic process GO:0010563 184 0.013
response to radiation GO:0009314 165 0.013
regulation of protein stability GO:0031647 52 0.013
negative regulation of protein processing GO:0010955 79 0.013
purine nucleoside triphosphate metabolic process GO:0009144 226 0.013
positive regulation of kinase activity GO:0033674 155 0.013
antibacterial peptide biosynthetic process GO:0002780 2 0.013
cellular divalent inorganic cation homeostasis GO:0072503 127 0.013
nuclear division GO:0000280 158 0.012
transmission of nerve impulse GO:0019226 76 0.012
female meiosis chromosome segregation GO:0016321 1 0.012
positive regulation of transferase activity GO:0051347 167 0.012
lipid catabolic process GO:0016042 69 0.012
nucleoside phosphate catabolic process GO:1901292 222 0.012
purine nucleotide catabolic process GO:0006195 211 0.012
regulation of circadian sleep wake cycle sleep GO:0045187 3 0.012
ossification GO:0001503 216 0.012
actin filament organization GO:0007015 113 0.012
purine ribonucleoside catabolic process GO:0046130 205 0.012
regulation of secretion GO:0051046 274 0.012
myosin filament organization GO:0031033 3 0.012
regulation of cell projection organization GO:0031344 206 0.012
monocarboxylic acid biosynthetic process GO:0072330 61 0.012
negative regulation of protein maturation GO:1903318 79 0.012
ribonucleoside catabolic process GO:0042454 206 0.012
myosin filament assembly GO:0031034 2 0.012
action potential GO:0001508 78 0.012
antimicrobial peptide biosynthetic process GO:0002777 2 0.012
negative regulation of endopeptidase activity GO:0010951 44 0.012
regulation of epithelial cell proliferation GO:0050678 141 0.012
ribose phosphate metabolic process GO:0019693 291 0.012
negative regulation of cellular component organization GO:0051129 194 0.012
alcohol biosynthetic process GO:0046165 43 0.012
negative regulation of serine type endopeptidase activity GO:1900004 2 0.012
embryonic placenta development GO:0001892 98 0.012
sulfur compound biosynthetic process GO:0044272 37 0.012
cellular carbohydrate metabolic process GO:0044262 119 0.012
regulation of protein serine threonine kinase activity GO:0071900 157 0.012
leukocyte migration GO:0050900 124 0.012
striated muscle myosin thick filament assembly GO:0071688 1 0.012
regulation of cellular component size GO:0032535 121 0.012
lymphocyte differentiation GO:0030098 242 0.012
regulation of purine nucleotide metabolic process GO:1900542 169 0.012
regulation of protein maturation GO:1903317 96 0.012
organelle localization GO:0051640 179 0.012
liver development GO:0001889 66 0.012
oxidative demethylation GO:0070989 1 0.012
purine nucleoside triphosphate catabolic process GO:0009146 203 0.011
oligopeptide transmembrane transport GO:0035672 4 0.011
purine containing compound catabolic process GO:0072523 213 0.011
carbohydrate derivative catabolic process GO:1901136 231 0.011
sterol metabolic process GO:0016125 58 0.011
regulation of leukocyte mediated immunity GO:0002703 104 0.011
peptidyl tyrosine phosphorylation GO:0018108 143 0.011
neuron neuron synaptic transmission GO:0007270 69 0.011
cation homeostasis GO:0055080 212 0.011
leukocyte mediated immunity GO:0002443 174 0.011
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.011
lipid transport GO:0006869 98 0.011
regulation of striated muscle cell differentiation GO:0051153 81 0.011
synaptic transmission GO:0007268 329 0.011
positive regulation of secretion by cell GO:1903532 114 0.011
endocytosis GO:0006897 168 0.011
organ growth GO:0035265 117 0.011
positive regulation of growth GO:0045927 104 0.011
ribonucleoside triphosphate metabolic process GO:0009199 220 0.011
striated muscle tissue development GO:0014706 293 0.011
extracellular matrix organization GO:0030198 147 0.011
heart morphogenesis GO:0003007 178 0.011
mitotic cell cycle process GO:1903047 159 0.011
blood vessel morphogenesis GO:0048514 285 0.011
connective tissue development GO:0061448 179 0.011
response to extracellular stimulus GO:0009991 127 0.011
negative regulation of protein modification process GO:0031400 163 0.011
carboxylic acid transport GO:0046942 100 0.011
negative regulation of phosphorylation GO:0042326 166 0.011
cholesterol metabolic process GO:0008203 56 0.011
regulation of intracellular transport GO:0032386 159 0.011
cofactor metabolic process GO:0051186 80 0.011
multicellular organismal homeostasis GO:0048871 164 0.011
carboxylic acid catabolic process GO:0046395 51 0.011
sulfate assimilation GO:0000103 3 0.011
regulation of ras protein signal transduction GO:0046578 114 0.011
protein localization to membrane GO:0072657 108 0.011
divalent metal ion transport GO:0070838 172 0.011
positive regulation of proteolysis GO:0045862 85 0.011
response to acid chemical GO:0001101 111 0.011
organophosphate biosynthetic process GO:0090407 122 0.011
response to peptide GO:1901652 136 0.011
regulation of apoptotic signaling pathway GO:2001233 197 0.011
regulation of nucleoside metabolic process GO:0009118 130 0.011
neuronal action potential GO:0019228 54 0.011
transepithelial chloride transport GO:0030321 4 0.011
regulation of cysteine type endopeptidase activity GO:2000116 65 0.011
positive regulation of immune effector process GO:0002699 107 0.011
urogenital system development GO:0001655 261 0.011
drug catabolic process GO:0042737 2 0.011
cellular protein catabolic process GO:0044257 155 0.011
amide transport GO:0042886 138 0.010
cytoplasmic transport GO:0016482 234 0.010
positive regulation of hydrolase activity GO:0051345 148 0.010
epithelial tube formation GO:0072175 130 0.010
inflammatory response GO:0006954 244 0.010
positive regulation of secretion GO:0051047 130 0.010
regulation of cellular response to stress GO:0080135 159 0.010
regulation of innate immune response GO:0045088 91 0.010
glucose homeostasis GO:0042593 128 0.010
gonad development GO:0008406 141 0.010
meiotic cell cycle GO:0051321 122 0.010
homeostasis of number of cells GO:0048872 210 0.010
response to light stimulus GO:0009416 135 0.010
antimicrobial peptide production GO:0002775 2 0.010
response to uv GO:0009411 44 0.010
positive regulation of protein kinase activity GO:0045860 144 0.010
cellular macromolecule catabolic process GO:0044265 206 0.010
negative regulation of defense response GO:0031348 77 0.010
myotube cell development GO:0014904 60 0.010
g protein coupled receptor signaling pathway GO:0007186 243 0.010
cellular response to acid chemical GO:0071229 68 0.010
developmental growth involved in morphogenesis GO:0060560 138 0.010
protein refolding GO:0042026 1 0.010
positive regulation of cellular catabolic process GO:0031331 148 0.010
glucose metabolic process GO:0006006 92 0.010
positive regulation of programmed cell death GO:0043068 218 0.010
protein ubiquitination GO:0016567 171 0.010
defecation GO:0030421 1 0.010
nucleoside monophosphate metabolic process GO:0009123 85 0.010

Defa24 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.023
inherited metabolic disorder DOID:655 0 0.021
disease of anatomical entity DOID:7 0 0.015
nervous system disease DOID:863 0 0.015
musculoskeletal system disease DOID:17 0 0.015
bone disease DOID:0080001 0 0.012
connective tissue disease DOID:65 0 0.012
immune system disease DOID:2914 0 0.010