Mus musculus

0 known processes

Insl5

insulin-like 5

(Aliases: RIF2)

Insl5 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
response to radiation GO:0009314 165 0.283
rhodopsin mediated signaling pathway GO:0016056 4 0.215
g protein coupled receptor signaling pathway GO:0007186 243 0.200
purine ribonucleotide metabolic process GO:0009150 290 0.190
transmembrane transport GO:0055085 412 0.148
ribose phosphate metabolic process GO:0019693 291 0.126
response to light stimulus GO:0009416 135 0.107
organic cyclic compound catabolic process GO:1901361 295 0.106
inorganic ion transmembrane transport GO:0098660 234 0.095
ribonucleotide metabolic process GO:0009259 291 0.092
macromolecule catabolic process GO:0009057 281 0.089
organonitrogen compound biosynthetic process GO:1901566 192 0.089
nucleotide metabolic process GO:0009117 332 0.089
ion transmembrane transport GO:0034220 361 0.084
nucleoside phosphate metabolic process GO:0006753 338 0.081
regulation of cell cycle GO:0051726 281 0.071
carbohydrate derivative biosynthetic process GO:1901137 183 0.069
detection of light stimulus GO:0009583 25 0.063
inorganic cation transmembrane transport GO:0098662 207 0.062
purine nucleotide metabolic process GO:0006163 302 0.062
purine containing compound metabolic process GO:0072521 311 0.060
regulation of response to wounding GO:1903034 189 0.059
fat soluble vitamin biosynthetic process GO:0042362 4 0.058
nucleobase containing small molecule metabolic process GO:0055086 352 0.056
divalent inorganic cation transport GO:0072511 178 0.055
regulation of cellular catabolic process GO:0031329 242 0.055
spermatid differentiation GO:0048515 115 0.055
regulation of purine nucleotide metabolic process GO:1900542 169 0.055
activation of immune response GO:0002253 138 0.055
learning or memory GO:0007611 148 0.054
oxidation reduction process GO:0055114 342 0.054
regulation of transmembrane transport GO:0034762 128 0.053
calcium ion transmembrane transport GO:0070588 85 0.053
detection of external stimulus GO:0009581 61 0.052
cellular nitrogen compound catabolic process GO:0044270 280 0.050
anatomical structure homeostasis GO:0060249 145 0.049
anion transport GO:0006820 177 0.049
cognition GO:0050890 149 0.048
detection of abiotic stimulus GO:0009582 60 0.045
regulation of thymocyte migration GO:2000410 2 0.045
multicellular organismal homeostasis GO:0048871 164 0.045
regulation of ion transport GO:0043269 215 0.043
cation transmembrane transport GO:0098655 266 0.043
organic acid transport GO:0015849 101 0.042
cellular component assembly involved in morphogenesis GO:0010927 139 0.041
camera type eye development GO:0043010 266 0.041
inflammatory response GO:0006954 244 0.040
learning GO:0007612 98 0.040
immune response regulating signaling pathway GO:0002764 125 0.040
cellular ketone metabolic process GO:0042180 84 0.040
sensory perception GO:0007600 245 0.040
cellular lipid metabolic process GO:0044255 323 0.040
regulation of ion transmembrane transport GO:0034765 119 0.039
regulation of membrane potential GO:0042391 192 0.039
regulation of nucleotide metabolic process GO:0006140 169 0.038
purine nucleotide catabolic process GO:0006195 211 0.038
detection of visible light GO:0009584 14 0.038
nucleoside triphosphate metabolic process GO:0009141 230 0.038
adult locomotory behavior GO:0008344 91 0.038
purine containing compound biosynthetic process GO:0072522 70 0.037
nitrogen compound transport GO:0071705 271 0.036
regulation of cellular amino acid metabolic process GO:0006521 5 0.036
peptidyl amino acid modification GO:0018193 336 0.035
protein catabolic process GO:0030163 221 0.035
fertilization GO:0009566 127 0.035
positive regulation of cellular catabolic process GO:0031331 148 0.035
muscle tissue development GO:0060537 308 0.034
cation transport GO:0006812 399 0.034
tissue homeostasis GO:0001894 115 0.033
blood circulation GO:0008015 195 0.033
regulation of neuron death GO:1901214 134 0.033
posttranscriptional regulation of gene expression GO:0010608 155 0.032
positive regulation of eosinophil migration GO:2000418 2 0.032
organ growth GO:0035265 117 0.032
Mouse
second messenger mediated signaling GO:0019932 73 0.032
Mouse
cell type specific apoptotic process GO:0097285 268 0.031
cellular amino acid metabolic process GO:0006520 103 0.031
purine containing compound catabolic process GO:0072523 213 0.031
cellular response to abiotic stimulus GO:0071214 56 0.030
circulatory system process GO:0003013 197 0.030
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.030
striated muscle contraction GO:0006941 45 0.030
apoptotic signaling pathway GO:0097190 306 0.029
cellular response to cytokine stimulus GO:0071345 189 0.029
digestive tract development GO:0048565 190 0.028
calcium ion homeostasis GO:0055074 127 0.028
ribonucleoside triphosphate metabolic process GO:0009199 220 0.028
purine nucleoside catabolic process GO:0006152 205 0.028
anion transmembrane transport GO:0098656 71 0.028
germ cell development GO:0007281 185 0.028
vitamin metabolic process GO:0006766 23 0.027
glycosyl compound catabolic process GO:1901658 206 0.027
purine ribonucleoside metabolic process GO:0046128 241 0.027
macromolecule methylation GO:0043414 120 0.027
cellular amine metabolic process GO:0044106 44 0.027
organonitrogen compound catabolic process GO:1901565 264 0.027
cyclic purine nucleotide metabolic process GO:0052652 43 0.027
sodium ion transmembrane transport GO:0035725 49 0.027
positive regulation of nucleotide metabolic process GO:0045981 114 0.027
regulation of system process GO:0044057 200 0.027
dna metabolic process GO:0006259 303 0.026
amine metabolic process GO:0009308 45 0.026
neuron apoptotic process GO:0051402 142 0.026
nucleoside metabolic process GO:0009116 246 0.026
purine nucleoside metabolic process GO:0042278 241 0.026
sodium ion transport GO:0006814 73 0.026
regulation of cellular ketone metabolic process GO:0010565 66 0.026
regulation of secretion by cell GO:1903530 249 0.026
phototransduction GO:0007602 17 0.026
skin development GO:0043588 220 0.026
male gamete generation GO:0048232 285 0.025
negative regulation of defense response GO:0031348 77 0.025
ribonucleoside catabolic process GO:0042454 206 0.025
wnt signaling pathway GO:0016055 188 0.025
synaptic transmission GO:0007268 329 0.025
positive regulation of innate immune response GO:0045089 80 0.025
cyclic nucleotide biosynthetic process GO:0009190 44 0.025
purine nucleoside triphosphate catabolic process GO:0009146 203 0.025
action potential GO:0001508 78 0.024
mapk cascade GO:0000165 281 0.024
positive regulation of defense response GO:0031349 124 0.024
nucleoside phosphate biosynthetic process GO:1901293 79 0.024
cellular calcium ion homeostasis GO:0006874 119 0.024
adult behavior GO:0030534 135 0.024
gland development GO:0048732 330 0.024
Mouse
small gtpase mediated signal transduction GO:0007264 97 0.024
response to growth factor GO:0070848 198 0.024
aromatic compound catabolic process GO:0019439 286 0.024
cellular metal ion homeostasis GO:0006875 151 0.024
protein modification by small protein conjugation or removal GO:0070647 207 0.024
multicellular organismal signaling GO:0035637 91 0.024
regulation of cell activation GO:0050865 289 0.024
purine ribonucleotide catabolic process GO:0009154 208 0.024
innate immune response GO:0045087 157 0.023
chloride transmembrane transport GO:1902476 24 0.023
positive regulation of programmed cell death GO:0043068 218 0.023
nucleoside catabolic process GO:0009164 206 0.023
muscle contraction GO:0006936 101 0.023
regulation of ion transmembrane transporter activity GO:0032412 54 0.023
regulation of t cell activation GO:0050863 170 0.022
spermatid development GO:0007286 108 0.022
neuron death GO:0070997 154 0.022
glutamate receptor signaling pathway GO:0007215 35 0.022
purine nucleotide biosynthetic process GO:0006164 65 0.022
locomotory behavior GO:0007626 195 0.022
purine nucleoside triphosphate metabolic process GO:0009144 226 0.022
organic anion transport GO:0015711 137 0.022
glycosyl compound metabolic process GO:1901657 246 0.022
organelle assembly GO:0070925 177 0.022
visual perception GO:0007601 52 0.021
cellular homeostasis GO:0019725 240 0.021
nucleoside triphosphate catabolic process GO:0009143 205 0.021
associative learning GO:0008306 61 0.021
negative regulation of protein complex disassembly GO:0043242 22 0.021
regulation of cellular amine metabolic process GO:0033238 20 0.021
sequestering of metal ion GO:0051238 19 0.021
regulation of erk1 and erk2 cascade GO:0070372 71 0.021
striated muscle tissue development GO:0014706 293 0.020
heterocycle catabolic process GO:0046700 280 0.020
negative regulation of cell proliferation GO:0008285 296 0.020
regulation of organelle organization GO:0033043 289 0.020
organophosphate biosynthetic process GO:0090407 122 0.020
erk1 and erk2 cascade GO:0070371 77 0.020
negative regulation of cell cycle GO:0045786 123 0.020
ribonucleotide biosynthetic process GO:0009260 59 0.020
sensory perception of light stimulus GO:0050953 54 0.020
negative regulation of multi organism process GO:0043901 68 0.020
cyclic nucleotide metabolic process GO:0009187 59 0.020
regulation of t cell differentiation GO:0045580 83 0.020
ensheathment of neurons GO:0007272 76 0.020
positive regulation of protein modification process GO:0031401 299 0.019
phototransduction visible light GO:0007603 6 0.019
peptidyl serine phosphorylation GO:0018105 74 0.019
response to organonitrogen compound GO:0010243 246 0.019
calcium ion transport GO:0006816 159 0.019
regulation of apoptotic signaling pathway GO:2001233 197 0.019
purine ribonucleotide biosynthetic process GO:0009152 59 0.019
protein modification by small protein removal GO:0070646 21 0.019
cellular macromolecule catabolic process GO:0044265 206 0.019
regulation of protein localization GO:0032880 231 0.019
microtubule cytoskeleton organization GO:0000226 157 0.019
nucleotide catabolic process GO:0009166 217 0.019
homeostasis of number of cells GO:0048872 210 0.019
regulation of anatomical structure size GO:0090066 178 0.019
regulation of protein kinase b signaling GO:0051896 56 0.018
spermatogenesis GO:0007283 284 0.018
inorganic anion transport GO:0015698 43 0.018
heart contraction GO:0060047 93 0.018
asymmetric stem cell division GO:0098722 3 0.018
skeletal muscle organ development GO:0060538 163 0.018
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.018
ribose phosphate biosynthetic process GO:0046390 59 0.018
rna processing GO:0006396 105 0.018
transmission of nerve impulse GO:0019226 76 0.018
nucleotide biosynthetic process GO:0009165 78 0.018
muscle system process GO:0003012 141 0.018
regulation of multi organism process GO:0043900 111 0.018
small molecule catabolic process GO:0044282 71 0.018
alcohol metabolic process GO:0006066 116 0.018
canonical wnt signaling pathway GO:0060070 130 0.018
cellular chemical homeostasis GO:0055082 215 0.017
cell chemotaxis GO:0060326 81 0.017
positive regulation of necrotic cell death GO:0010940 1 0.017
visual behavior GO:0007632 45 0.017
sensory perception of sound GO:0007605 97 0.017
organophosphate catabolic process GO:0046434 232 0.017
divalent metal ion transport GO:0070838 172 0.017
carbohydrate derivative catabolic process GO:1901136 231 0.017
positive regulation of cell death GO:0010942 224 0.017
cellular response to organonitrogen compound GO:0071417 145 0.017
multicellular organismal response to stress GO:0033555 62 0.017
ribonucleoside metabolic process GO:0009119 245 0.017
ras protein signal transduction GO:0007265 77 0.017
developmental maturation GO:0021700 193 0.017
regulation of leukocyte differentiation GO:1902105 159 0.017
regulation of neuron differentiation GO:0045664 281 0.017
regulation of establishment of protein localization GO:0070201 181 0.016
mitotic cell cycle process GO:1903047 159 0.016
t cell differentiation GO:0030217 174 0.016
negative regulation of immune system process GO:0002683 209 0.016
mitotic cell cycle GO:0000278 195 0.016
response to organic cyclic compound GO:0014070 198 0.016
oocyte maturation GO:0001556 18 0.016
regulation of cellular component biogenesis GO:0044087 181 0.016
maintenance of location GO:0051235 89 0.016
carbohydrate metabolic process GO:0005975 230 0.016
neural precursor cell proliferation GO:0061351 121 0.016
lipid biosynthetic process GO:0008610 179 0.016
axon guidance GO:0007411 141 0.016
regulation of lymphocyte activation GO:0051249 240 0.016
cation homeostasis GO:0055080 212 0.016
regulation of mapk cascade GO:0043408 248 0.016
intracellular mrna localization GO:0008298 4 0.016
nucleoside phosphate catabolic process GO:1901292 222 0.016
regulation of homeostatic process GO:0032844 182 0.016
regulation of cell cycle process GO:0010564 160 0.016
tumor necrosis factor ligand superfamily member 11 production GO:0072535 1 0.016
cellular ion homeostasis GO:0006873 165 0.016
cellular response to growth factor stimulus GO:0071363 197 0.016
regulation of kinase activity GO:0043549 249 0.016
positive regulation of membrane protein ectodomain proteolysis GO:0051044 3 0.016
heart process GO:0003015 94 0.016
protein kinase b signaling GO:0043491 74 0.016
epidermis development GO:0008544 187 0.015
regulation of defense response GO:0031347 233 0.015
immune response activating signal transduction GO:0002757 116 0.015
positive regulation of thymocyte migration GO:2000412 2 0.015
regulation of inflammatory response GO:0050727 147 0.015
negative regulation of cytokine production GO:0001818 84 0.015
positive regulation of protein catabolic process GO:0045732 60 0.015
inorganic anion transmembrane transport GO:0098661 29 0.015
retina development in camera type eye GO:0060041 119 0.015
stem cell development GO:0048864 219 0.015
protein localization to organelle GO:0033365 185 0.015
regulation of isoprenoid metabolic process GO:0019747 1 0.015
cellular response to light stimulus GO:0071482 19 0.015
prevention of polyspermy GO:0060468 4 0.015
ribonucleotide catabolic process GO:0009261 208 0.015
reactive oxygen species metabolic process GO:0072593 84 0.015
cytoplasmic transport GO:0016482 234 0.015
glycoprotein metabolic process GO:0009100 116 0.015
positive regulation of cell motility GO:2000147 116 0.015
detection of stimulus GO:0051606 84 0.015
regulation of reactive oxygen species metabolic process GO:2000377 40 0.015
regulation of nucleoside metabolic process GO:0009118 130 0.015
detection of chemical stimulus involved in sensory perception of taste GO:0050912 3 0.015
leukocyte differentiation GO:0002521 342 0.014
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.014
wound healing GO:0042060 157 0.014
glial cell differentiation GO:0010001 131 0.014
small molecule biosynthetic process GO:0044283 132 0.014
regulation of cytokine production GO:0001817 266 0.014
organic acid biosynthetic process GO:0016053 86 0.014
regulation of cell motility GO:2000145 236 0.014
metal ion homeostasis GO:0055065 189 0.014
neuronal action potential GO:0019228 54 0.014
cellular alcohol biosynthetic process GO:0044108 3 0.014
protein autophosphorylation GO:0046777 61 0.014
regulation of cell projection organization GO:0031344 206 0.014
cellular divalent inorganic cation homeostasis GO:0072503 127 0.014
heart morphogenesis GO:0003007 178 0.014
blood vessel morphogenesis GO:0048514 285 0.014
neuron migration GO:0001764 122 0.014
regulation of protein catabolic process GO:0042176 108 0.014
negative regulation of phosphate metabolic process GO:0045936 184 0.014
pigmentation GO:0043473 71 0.014
regulation of purine nucleotide catabolic process GO:0033121 122 0.014
regulation of innate immune response GO:0045088 91 0.014
regulation of eosinophil migration GO:2000416 2 0.014
positive regulation of protein kinase b signaling GO:0051897 32 0.014
cellular protein catabolic process GO:0044257 155 0.014
microtubule based process GO:0007017 236 0.014
lymphocyte differentiation GO:0030098 242 0.014
positive regulation of leukocyte differentiation GO:1902107 86 0.013
peptidyl serine modification GO:0018209 83 0.013
extrinsic apoptotic signaling pathway GO:0097191 126 0.013
carboxylic acid transport GO:0046942 100 0.013
muscle cell development GO:0055001 133 0.013
modification dependent macromolecule catabolic process GO:0043632 133 0.013
nuclear transport GO:0051169 139 0.013
negative regulation of phosphorus metabolic process GO:0010563 184 0.013
activation of mapk activity involved in innate immune response GO:0035419 2 0.013
visual learning GO:0008542 44 0.013
gtp catabolic process GO:0006184 143 0.013
sequestering of calcium ion GO:0051208 18 0.013
dendrite development GO:0016358 115 0.013
regulation of transferase activity GO:0051338 263 0.013
angiogenesis GO:0001525 201 0.013
adult walking behavior GO:0007628 41 0.013
regulation of blood pressure GO:0008217 93 0.013
b cell activation GO:0042113 161 0.013
methylation GO:0032259 134 0.013
sperm motility GO:0030317 47 0.013
regulation of hormone levels GO:0010817 211 0.013
membrane lipid biosynthetic process GO:0046467 32 0.013
response to acid chemical GO:0001101 111 0.013
peptide transport GO:0015833 133 0.013
negative regulation of organelle organization GO:0010639 90 0.013
regulation of lipid metabolic process GO:0019216 118 0.012
regulation of cell migration GO:0030334 219 0.012
regulation of transporter activity GO:0032409 57 0.012
negative regulation of intracellular signal transduction GO:1902532 167 0.012
intrinsic apoptotic signaling pathway GO:0097193 132 0.012
negative regulation of secretion by cell GO:1903531 54 0.012
satellite cell activation involved in skeletal muscle regeneration GO:0014901 3 0.012
response to amino acid GO:0043200 37 0.012
cardiac muscle contraction GO:0060048 32 0.012
cellular response to acid chemical GO:0071229 68 0.012
axonogenesis GO:0007409 274 0.012
sphingolipid biosynthetic process GO:0030148 26 0.012
regulation of proteolysis GO:0030162 164 0.012
regulation of phospholipid biosynthetic process GO:0071071 3 0.012
positive regulation of protein transport GO:0051222 93 0.012
regulation of hydrolase activity GO:0051336 246 0.012
chromatin modification GO:0016568 187 0.012
ceramide biosynthetic process GO:0046513 20 0.012
eosinophil migration GO:0072677 3 0.012
monocarboxylic acid transport GO:0015718 44 0.012
protein methylation GO:0006479 81 0.012
pallium development GO:0021543 120 0.012
positive regulation of transferase activity GO:0051347 167 0.012
embryonic organ morphogenesis GO:0048562 276 0.012
cytokine mediated signaling pathway GO:0019221 115 0.012
purine ribonucleoside catabolic process GO:0046130 205 0.012
regulation of cellular component size GO:0032535 121 0.012
single fertilization GO:0007338 82 0.012
asymmetric neuroblast division GO:0055059 1 0.012
rho protein signal transduction GO:0007266 32 0.012
myotube differentiation GO:0014902 105 0.012
positive regulation of hydrolase activity GO:0051345 148 0.012
cilium assembly GO:0042384 81 0.011
mrna metabolic process GO:0016071 84 0.011
regulation of gtp catabolic process GO:0033124 113 0.011
negative regulation of protein transport GO:0051224 46 0.011
regulation of protein transport GO:0051223 163 0.011
nuclear division GO:0000280 158 0.011
response to pain GO:0048265 26 0.011
cellular carbohydrate metabolic process GO:0044262 119 0.011
cellularization GO:0007349 1 0.011
regulation of lymphocyte differentiation GO:0045619 107 0.011
regulation of extrinsic apoptotic signaling pathway GO:2001236 77 0.011
cytokine production GO:0001816 319 0.011
regulation of blood circulation GO:1903522 93 0.011
regulation of cyclic nucleotide metabolic process GO:0030799 40 0.011
negative regulation of cellular protein metabolic process GO:0032269 247 0.011
negative regulation of cellular component organization GO:0051129 194 0.011
negative regulation of sterol transport GO:0032372 4 0.011
regulation of satellite cell activation involved in skeletal muscle regeneration GO:0014717 3 0.011
peptide hormone secretion GO:0030072 109 0.011
positive regulation of erk1 and erk2 cascade GO:0070374 47 0.011
regulation of cell division GO:0051302 76 0.011
transepithelial chloride transport GO:0030321 4 0.011
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.011
sensory organ morphogenesis GO:0090596 242 0.011
organic hydroxy compound metabolic process GO:1901615 203 0.011
cilium morphogenesis GO:0060271 102 0.011
gamma aminobutyric acid signaling pathway GO:0007214 8 0.011
sulfur compound metabolic process GO:0006790 100 0.011
positive regulation of nervous system development GO:0051962 221 0.011
negative regulation of protein metabolic process GO:0051248 282 0.011
epithelial tube morphogenesis GO:0060562 303 0.011
rna splicing GO:0008380 54 0.011
guanosine containing compound catabolic process GO:1901069 144 0.010
protein alkylation GO:0008213 81 0.010
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.010
vitamin a metabolic process GO:0006776 2 0.010
negative regulation of interleukin 5 production GO:0032714 4 0.010
regulation of body fluid levels GO:0050878 162 0.010
positive regulation of cellular amine metabolic process GO:0033240 5 0.010
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 55 0.010
nucleoside monophosphate metabolic process GO:0009123 85 0.010
response to inorganic substance GO:0010035 96 0.010
positive regulation of protein phosphorylation GO:0001934 242 0.010
regulation of ras gtpase activity GO:0032318 88 0.010
chromatin organization GO:0006325 206 0.010
memory GO:0007613 58 0.010
adaptation of rhodopsin mediated signaling GO:0016062 2 0.010
fibronectin dependent thymocyte migration GO:0072681 1 0.010
membrane organization GO:0061024 245 0.010
ribonucleoside monophosphate metabolic process GO:0009161 80 0.010
neuromuscular process GO:0050905 99 0.010
endocytosis GO:0006897 168 0.010
regulation of g protein coupled receptor protein signaling pathway GO:0008277 37 0.010
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.010
negative regulation of neuron death GO:1901215 98 0.010
regulation of protein binding GO:0043393 60 0.010

Insl5 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
sensory system disease DOID:0050155 0 0.052
disease of anatomical entity DOID:7 0 0.052
eye and adnexa disease DOID:1492 0 0.052
nervous system disease DOID:863 0 0.052
eye disease DOID:5614 0 0.052
retinal disease DOID:5679 0 0.040
retinal degeneration DOID:8466 0 0.040
retinitis pigmentosa DOID:10584 0 0.040
musculoskeletal system disease DOID:17 0 0.013