Mus musculus

23 known processes

Adam24

a disintegrin and metallopeptidase domain 24 (testase 1)

(Aliases: Dtgn5)

Adam24 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular homeostasis GO:0019725 240 0.091
cation transport GO:0006812 399 0.079
spermatogenesis GO:0007283 284 0.073
regulation of membrane potential GO:0042391 192 0.063
Mouse
fertilization GO:0009566 127 0.057
male gamete generation GO:0048232 285 0.052
cellular chemical homeostasis GO:0055082 215 0.051
spermatid differentiation GO:0048515 115 0.049
regulation of cellular ketone metabolic process GO:0010565 66 0.049
leukocyte differentiation GO:0002521 342 0.049
Mouse
positive regulation of thymocyte migration GO:2000412 2 0.046
Mouse
cellular ketone metabolic process GO:0042180 84 0.043
regulation of hormone levels GO:0010817 211 0.037
ion transmembrane transport GO:0034220 361 0.034
regulation of cellular amino acid metabolic process GO:0006521 5 0.033
protein catabolic process GO:0030163 221 0.033
Mouse
cellular amine metabolic process GO:0044106 44 0.032
cation transmembrane transport GO:0098655 266 0.031
small gtpase mediated signal transduction GO:0007264 97 0.031
regulation of t cell activation GO:0050863 170 0.031
Mouse
glucose homeostasis GO:0042593 128 0.031
muscle tissue development GO:0060537 308 0.031
regulation of lymphocyte activation GO:0051249 240 0.031
Mouse
transmembrane transport GO:0055085 412 0.029
neuronal action potential GO:0019228 54 0.029
Mouse
cellular amino acid metabolic process GO:0006520 103 0.028
germ cell development GO:0007281 185 0.028
cellular ion homeostasis GO:0006873 165 0.027
hematopoietic progenitor cell differentiation GO:0002244 143 0.027
single fertilization GO:0007338 82 0.026
regulation of cell cycle GO:0051726 281 0.026
regulation of transferase activity GO:0051338 263 0.026
Mouse
regulation of response to wounding GO:1903034 189 0.026
Mouse
response to radiation GO:0009314 165 0.026
Mouse
striated muscle tissue development GO:0014706 293 0.025
action potential GO:0001508 78 0.025
Mouse
t cell activation GO:0042110 289 0.025
Mouse
mitochondrion organization GO:0007005 134 0.025
leukocyte mediated immunity GO:0002443 174 0.024
muscle system process GO:0003012 141 0.024
inflammatory response GO:0006954 244 0.024
Mouse
carbohydrate homeostasis GO:0033500 128 0.024
cellular response to hexose stimulus GO:0071331 47 0.024
nitrogen compound transport GO:0071705 271 0.024
inorganic cation transmembrane transport GO:0098662 207 0.023
positive regulation of protein modification process GO:0031401 299 0.023
Mouse
epithelial cell proliferation GO:0050673 174 0.023
physiological cardiac muscle hypertrophy GO:0003301 3 0.022
regulation of cellular amine metabolic process GO:0033238 20 0.022
peptidyl amino acid modification GO:0018193 336 0.022
exocytosis GO:0006887 121 0.022
protein maturation GO:0051604 176 0.022
striated muscle cell development GO:0055002 125 0.021
aromatic compound catabolic process GO:0019439 286 0.021
cellular response to carbohydrate stimulus GO:0071322 50 0.020
spermatid development GO:0007286 108 0.020
activation of mapk activity involved in innate immune response GO:0035419 2 0.020
Mouse
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.020
Mouse
regulation of protein kinase activity GO:0045859 232 0.020
Mouse
carbohydrate metabolic process GO:0005975 230 0.020
heterocycle catabolic process GO:0046700 280 0.020
regulation of epithelial cell proliferation GO:0050678 141 0.020
carbohydrate derivative catabolic process GO:1901136 231 0.020
rho protein signal transduction GO:0007266 32 0.020
anion transport GO:0006820 177 0.020
response to organonitrogen compound GO:0010243 246 0.020
regulation of lymphocyte differentiation GO:0045619 107 0.020
Mouse
blood vessel morphogenesis GO:0048514 285 0.019
Mouse
eosinophil migration GO:0072677 3 0.019
Mouse
cellular nitrogen compound catabolic process GO:0044270 280 0.019
cation homeostasis GO:0055080 212 0.019
cell growth involved in cardiac muscle cell development GO:0061049 3 0.019
mapk cascade GO:0000165 281 0.018
Mouse
positive regulation of kinase activity GO:0033674 155 0.018
Mouse
regulation of eosinophil migration GO:2000416 2 0.018
Mouse
apoptotic signaling pathway GO:0097190 306 0.018
regulation of binding GO:0051098 111 0.018
macromolecule catabolic process GO:0009057 281 0.018
Mouse
anatomical structure homeostasis GO:0060249 145 0.017
Mouse
cytoplasmic transport GO:0016482 234 0.017
regulation of cell growth involved in cardiac muscle cell development GO:0061050 3 0.017
phospholipid metabolic process GO:0006644 87 0.017
negative regulation of molecular function GO:0044092 258 0.017
regulation of hydrolase activity GO:0051336 246 0.017
regulation of cellular component biogenesis GO:0044087 181 0.017
regulation of cellular catabolic process GO:0031329 242 0.017
Mouse
regulation of intracellular transport GO:0032386 159 0.017
regulation of cell activation GO:0050865 289 0.017
Mouse
positive regulation of cellular amine metabolic process GO:0033240 5 0.017
muscle cell development GO:0055001 133 0.017
lymphocyte mediated immunity GO:0002449 139 0.017
kidney development GO:0001822 213 0.017
glycoprotein metabolic process GO:0009100 116 0.016
cellular response to peptide hormone stimulus GO:0071375 92 0.016
regulation of neuron differentiation GO:0045664 281 0.016
negative regulation of phosphorylation GO:0042326 166 0.016
carbohydrate derivative biosynthetic process GO:1901137 183 0.016
regulation of kinase activity GO:0043549 249 0.016
Mouse
divalent inorganic cation homeostasis GO:0072507 138 0.016
connective tissue development GO:0061448 179 0.016
cellular calcium ion homeostasis GO:0006874 119 0.016
sensory perception GO:0007600 245 0.016
embryonic organ morphogenesis GO:0048562 276 0.016
positive regulation of protein phosphorylation GO:0001934 242 0.016
Mouse
circadian rhythm GO:0007623 114 0.016
cellular response to lipid GO:0071396 145 0.016
posttranscriptional regulation of gene expression GO:0010608 155 0.016
organic cyclic compound catabolic process GO:1901361 295 0.016
protein processing GO:0016485 163 0.015
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.015
Mouse
multi multicellular organism process GO:0044706 109 0.015
regulation of secretion by cell GO:1903530 249 0.015
metal ion homeostasis GO:0055065 189 0.015
regulation of cell motility GO:2000145 236 0.015
Mouse
positive regulation of transferase activity GO:0051347 167 0.015
Mouse
negative regulation of cell growth involved in cardiac muscle cell development GO:0061052 2 0.015
response to nutrient levels GO:0031667 109 0.015
regulation of proteolysis GO:0030162 164 0.015
Mouse
lymphocyte differentiation GO:0030098 242 0.015
Mouse
response to peptide GO:1901652 136 0.015
olfactory learning GO:0008355 2 0.015
cellular lipid metabolic process GO:0044255 323 0.015
renal system development GO:0072001 225 0.015
response to light stimulus GO:0009416 135 0.015
Mouse
organelle fission GO:0048285 170 0.015
regulation of circadian sleep wake cycle GO:0042749 3 0.014
meiotic nuclear division GO:0007126 115 0.014
myelination GO:0042552 74 0.014
Mouse
cellular response to testosterone stimulus GO:0071394 1 0.014
oxidation reduction process GO:0055114 342 0.014
positive regulation of lymphocyte activation GO:0051251 140 0.014
Mouse
negative regulation of cellular protein metabolic process GO:0032269 247 0.014
urogenital system development GO:0001655 261 0.014
cellular response to organonitrogen compound GO:0071417 145 0.014
cellular response to peptide GO:1901653 92 0.014
cellular response to cytokine stimulus GO:0071345 189 0.014
regulation of secretion GO:0051046 274 0.014
fat cell differentiation GO:0045444 160 0.014
response to extracellular stimulus GO:0009991 127 0.014
cellular divalent inorganic cation homeostasis GO:0072503 127 0.014
muscle cell differentiation GO:0042692 261 0.014
regulation of neuron death GO:1901214 134 0.014
Mouse
insulin receptor signaling pathway GO:0008286 49 0.014
organonitrogen compound catabolic process GO:1901565 264 0.014
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 87 0.014
cognition GO:0050890 149 0.013
Mouse
protein modification by small protein conjugation GO:0032446 187 0.013
myotube differentiation GO:0014902 105 0.013
nucleocytoplasmic transport GO:0006913 139 0.013
nuclear division GO:0000280 158 0.013
cellular glucose homeostasis GO:0001678 52 0.013
sequestering of metal ion GO:0051238 19 0.013
physiological muscle hypertrophy GO:0003298 3 0.013
defense response to bacterium GO:0042742 119 0.013
leukocyte proliferation GO:0070661 172 0.013
ras protein signal transduction GO:0007265 77 0.013
endocytosis GO:0006897 168 0.013
immune effector process GO:0002252 321 0.013
methylation GO:0032259 134 0.013
regulation of protein catabolic process GO:0042176 108 0.013
Mouse
negative regulation of protein phosphorylation GO:0001933 126 0.013
purine nucleotide metabolic process GO:0006163 302 0.013
nucleoside phosphate catabolic process GO:1901292 222 0.013
extracellular structure organization GO:0043062 148 0.013
sperm egg recognition GO:0035036 37 0.013
Mouse
response to monosaccharide GO:0034284 67 0.013
cellular macromolecule catabolic process GO:0044265 206 0.013
actin cytoskeleton organization GO:0030036 220 0.013
insulin secretion GO:0030073 89 0.013
camera type eye development GO:0043010 266 0.013
negative regulation of protein metabolic process GO:0051248 282 0.013
positive regulation of eosinophil migration GO:2000418 2 0.013
Mouse
dna metabolic process GO:0006259 303 0.013
response to peptide hormone GO:0043434 127 0.012
regulation of organelle organization GO:0033043 289 0.012
glycoprotein biosynthetic process GO:0009101 89 0.012
skeletal system morphogenesis GO:0048705 203 0.012
tube formation GO:0035148 140 0.012
gland development GO:0048732 330 0.012
regulation of protein serine threonine kinase activity GO:0071900 157 0.012
Mouse
regulation of protein processing GO:0070613 96 0.012
macromolecule methylation GO:0043414 120 0.012
cellular response to transforming growth factor beta stimulus GO:0071560 88 0.012
Mouse
cellular response to glucose stimulus GO:0071333 45 0.012
sequestering of calcium ion GO:0051208 18 0.012
negative regulation of blood vessel endothelial cell migration GO:0043537 3 0.012
cellular response to organic cyclic compound GO:0071407 87 0.012
nucleobase containing small molecule metabolic process GO:0055086 352 0.012
positive regulation of map kinase activity GO:0043406 84 0.012
Mouse
hormone secretion GO:0046879 128 0.012
peptide secretion GO:0002790 114 0.012
response to testosterone GO:0033574 3 0.012
purine ribonucleoside metabolic process GO:0046128 241 0.012
multicellular organism growth GO:0035264 161 0.011
rhythmic process GO:0048511 174 0.011
protein modification by small protein conjugation or removal GO:0070647 207 0.011
regulation of multi organism process GO:0043900 111 0.011
chemotaxis GO:0006935 247 0.011
Mouse
regulation of cell projection organization GO:0031344 206 0.011
respiratory system development GO:0060541 190 0.011
nucleotide catabolic process GO:0009166 217 0.011
protein kinase b signaling GO:0043491 74 0.011
Mouse
regulation of insulin secretion involved in cellular response to glucose stimulus GO:0061178 31 0.011
divalent metal ion transport GO:0070838 172 0.011
learning or memory GO:0007611 148 0.011
Mouse
transition metal ion homeostasis GO:0055076 54 0.011
negative regulation of cell development GO:0010721 169 0.011
nucleoside triphosphate metabolic process GO:0009141 230 0.011
stem cell development GO:0048864 219 0.011
Mouse
regulation of establishment of protein localization GO:0070201 181 0.011
cellular response to hormone stimulus GO:0032870 150 0.011
compound eye development GO:0048749 1 0.011
wnt signaling pathway GO:0016055 188 0.011
protein ubiquitination GO:0016567 171 0.011
blastocyst development GO:0001824 80 0.011
maintenance of location GO:0051235 89 0.011
regulation of t cell proliferation GO:0042129 92 0.011
peptide transport GO:0015833 133 0.011
regulation of striated muscle cell differentiation GO:0051153 81 0.011
response to organic cyclic compound GO:0014070 198 0.011
Mouse
negative regulation of response to wounding GO:1903035 77 0.011
ribonucleotide catabolic process GO:0009261 208 0.011
cellular metal ion homeostasis GO:0006875 151 0.011
regulation of defense response GO:0031347 233 0.011
Mouse
response to transforming growth factor beta GO:0071559 88 0.011
Mouse
negative regulation of cellular component organization GO:0051129 194 0.010
positive regulation of membrane protein ectodomain proteolysis GO:0051044 3 0.010
Mouse
tissue homeostasis GO:0001894 115 0.010
Mouse
single organism cell adhesion GO:0098602 156 0.010
Mouse
regulation of muscle tissue development GO:1901861 97 0.010
positive regulation of defense response GO:0031349 124 0.010
Mouse
calcium ion homeostasis GO:0055074 127 0.010
endomembrane system organization GO:0010256 147 0.010
ribonucleoside metabolic process GO:0009119 245 0.010
purine containing compound metabolic process GO:0072521 311 0.010
amide transport GO:0042886 138 0.010
b cell mediated immunity GO:0019724 71 0.010
intracellular protein transport GO:0006886 204 0.010
cellular carbohydrate metabolic process GO:0044262 119 0.010
purine nucleoside triphosphate catabolic process GO:0009146 203 0.010
response to insulin GO:0032868 100 0.010
cellular response to monosaccharide stimulus GO:0071326 47 0.010
purine ribonucleotide catabolic process GO:0009154 208 0.010
purine containing compound catabolic process GO:0072523 213 0.010
ribose phosphate metabolic process GO:0019693 291 0.010
negative regulation of endothelial cell migration GO:0010596 4 0.010
organophosphate catabolic process GO:0046434 232 0.010
negative regulation of oxidative stress induced intrinsic apoptotic signaling pathway GO:1902176 4 0.010
organic hydroxy compound transport GO:0015850 93 0.010
ribonucleotide metabolic process GO:0009259 291 0.010
extracellular matrix organization GO:0030198 147 0.010
epithelial cell development GO:0002064 159 0.010

Adam24 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.033
nervous system disease DOID:863 0 0.033
disease of metabolism DOID:0014667 0 0.016
cancer DOID:162 0 0.012
disease of cellular proliferation DOID:14566 0 0.012
sensory system disease DOID:0050155 0 0.011