Mus musculus

20 known processes

Ifit1

interferon-induced protein with tetratricopeptide repeats 1

(Aliases: ISG56,Ifi56)

Ifit1 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
cellular response to interferon beta GO:0035458 21 1.000
cellular response to interferon alpha GO:0035457 4 0.997
rig i signaling pathway GO:0039529 4 0.980
negative regulation of viral process GO:0048525 23 0.969
Human
positive regulation of rig i signaling pathway GO:1900246 1 0.961
negative regulation of defense response to virus by host GO:0050689 1 0.905
Human
regulation of viral genome replication GO:0045069 13 0.905
Human
negative regulation of viral genome replication GO:0045071 10 0.900
Human
regulation of multi organism process GO:0043900 111 0.892
Human
viral life cycle GO:0019058 36 0.888
Human
response to protozoan GO:0001562 28 0.885
regulation of rig i signaling pathway GO:0039535 2 0.839
defense response to bacterium GO:0042742 119 0.826
cytoplasmic pattern recognition receptor signaling pathway in response to virus GO:0039528 4 0.818
positive regulation of interferon alpha production GO:0032727 4 0.801
defense response to other organism GO:0098542 197 0.793
Human
response to interferon beta GO:0035456 22 0.788
interspecies interaction between organisms GO:0044419 83 0.784
Human
ribonucleoside catabolic process GO:0042454 206 0.771
viral process GO:0016032 41 0.760
Human
symbiosis encompassing mutualism through parasitism GO:0044403 83 0.749
Human
t helper 2 cell cytokine production GO:0035745 4 0.741
cellular response to cytokine stimulus GO:0071345 189 0.726
regulation of cytokine production GO:0001817 266 0.716
pattern recognition receptor signaling pathway GO:0002221 47 0.707
nucleoside triphosphate catabolic process GO:0009143 205 0.691
cellular nitrogen compound catabolic process GO:0044270 280 0.677
isg15 protein conjugation GO:0032020 4 0.662
innate immune response GO:0045087 157 0.661
Human
regulation of defense response to virus by host GO:0050691 8 0.655
Human
regulation of interferon alpha production GO:0032647 5 0.624
protein modification by small protein conjugation or removal GO:0070647 207 0.622
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 52 0.621
Human
ribose phosphate metabolic process GO:0019693 291 0.573
protein modification by small protein conjugation GO:0032446 187 0.572
glycosyl compound catabolic process GO:1901658 206 0.567
nucleotide catabolic process GO:0009166 217 0.545
negative regulation of multi organism process GO:0043901 68 0.527
Human
activation of innate immune response GO:0002218 56 0.522
response to phenylpropanoid GO:0080184 22 0.520
Mouse
negative regulation of cell proliferation GO:0008285 296 0.502
purine ribonucleotide metabolic process GO:0009150 290 0.487
mda 5 signaling pathway GO:0039530 1 0.481
positive regulation of interferon beta production GO:0032728 8 0.475
positive regulation of type i interferon production GO:0032481 14 0.472
defense response to virus GO:0051607 68 0.470
Human
interferon beta production GO:0032608 16 0.455
cd8 positive alpha beta t cell proliferation GO:0035740 1 0.454
heterocycle catabolic process GO:0046700 280 0.451
purine containing compound catabolic process GO:0072523 213 0.440
response to organic cyclic compound GO:0014070 198 0.435
Human Mouse
positive regulation of type i interferon mediated signaling pathway GO:0060340 4 0.435
response to interferon gamma GO:0034341 34 0.425
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.425
organophosphate catabolic process GO:0046434 232 0.420
negative regulation of cellular protein metabolic process GO:0032269 247 0.410
immune effector process GO:0002252 321 0.402
Human
purine ribonucleoside metabolic process GO:0046128 241 0.401
purine ribonucleotide catabolic process GO:0009154 208 0.397
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.378
nucleoside phosphate metabolic process GO:0006753 338 0.369
schwann cell proliferation GO:0014010 2 0.354
regulation of protein transport GO:0051223 163 0.341
purine containing compound metabolic process GO:0072521 311 0.334
negative regulation of defense response to virus GO:0050687 6 0.329
Human
type i interferon production GO:0032606 29 0.325
nucleotide metabolic process GO:0009117 332 0.324
glycosyl compound metabolic process GO:1901657 246 0.323
regulation of myd88 dependent toll like receptor signaling pathway GO:0034124 2 0.317
modification dependent macromolecule catabolic process GO:0043632 133 0.317
regulation of viral induced cytoplasmic pattern recognition receptor signaling pathway GO:0039531 2 0.302
pre mirna processing GO:0031054 3 0.301
viral gene expression GO:0019080 3 0.296
organic cyclic compound catabolic process GO:1901361 295 0.279
nucleoside metabolic process GO:0009116 246 0.274
cellular response to interferon gamma GO:0071346 25 0.273
regulation of neutrophil mediated killing of gram negative bacterium GO:0070951 1 0.269
regulation of defense response to bacterium GO:1900424 3 0.263
innate immune response activating signal transduction GO:0002758 50 0.262
negative regulation of interferon alpha production GO:0032687 1 0.260
nucleoside phosphate catabolic process GO:1901292 222 0.254
viral genome replication GO:0019079 17 0.248
Human
regulation of defense response GO:0031347 233 0.245
Human
positive regulation of immune effector process GO:0002699 107 0.242
negative regulation of cytokine production GO:0001818 84 0.240
aromatic compound catabolic process GO:0019439 286 0.228
regulation of schwann cell proliferation GO:0010624 2 0.223
ribonucleotide metabolic process GO:0009259 291 0.218
regulation of type i interferon production GO:0032479 22 0.214
organonitrogen compound catabolic process GO:1901565 264 0.212
response to type i interferon GO:0034340 12 0.211
Human
nucleobase containing small molecule metabolic process GO:0055086 352 0.209
purine ribonucleoside catabolic process GO:0046130 205 0.208
regulation of cellular component biogenesis GO:0044087 181 0.207
defense response to protozoan GO:0042832 25 0.207
nucleoside catabolic process GO:0009164 206 0.200
ribonucleoside triphosphate metabolic process GO:0009199 220 0.199
purine nucleoside metabolic process GO:0042278 241 0.192
regulation of response to biotic stimulus GO:0002831 38 0.188
Human
purine nucleoside triphosphate metabolic process GO:0009144 226 0.187
carbohydrate derivative catabolic process GO:1901136 231 0.186
purine nucleoside catabolic process GO:0006152 205 0.186
production of small rna involved in gene silencing by rna GO:0070918 6 0.185
regulation of regulatory t cell differentiation GO:0045589 7 0.182
viral transcription GO:0019083 3 0.177
toll like receptor 7 signaling pathway GO:0034154 4 0.177
regulation of t helper 2 cell cytokine production GO:2000551 3 0.175
cellular response to lipid GO:0071396 145 0.173
muscle tissue development GO:0060537 308 0.173
protein ubiquitination GO:0016567 171 0.169
ribonucleotide catabolic process GO:0009261 208 0.168
gene silencing by mirna GO:0035195 10 0.163
t helper 17 cell lineage commitment GO:0072540 4 0.163
regulation of toll like receptor signaling pathway GO:0034121 20 0.160
positive regulation of defense response GO:0031349 124 0.155
cytoplasmic transport GO:0016482 234 0.153
negative regulation of viral release from host cell GO:1902187 6 0.153
negative regulation of interferon beta production GO:0032688 3 0.152
nucleoside triphosphate metabolic process GO:0009141 230 0.151
defense response to gram positive bacterium GO:0050830 50 0.150
gtp catabolic process GO:0006184 143 0.149
purine nucleoside triphosphate catabolic process GO:0009146 203 0.149
ribonucleoside metabolic process GO:0009119 245 0.144
cytokine production GO:0001816 319 0.144
immune response regulating signaling pathway GO:0002764 125 0.140
myeloid leukocyte differentiation GO:0002573 119 0.139
positive regulation of t helper 2 cell cytokine production GO:2000553 3 0.137
histone h4 acetylation GO:0043967 10 0.134
myeloid cell homeostasis GO:0002262 114 0.133
purine nucleotide metabolic process GO:0006163 302 0.130
ribonucleoside triphosphate catabolic process GO:0009203 199 0.128
response to interferon alpha GO:0035455 7 0.124
positive regulation of viral entry into host cell GO:0046598 3 0.123
regulation of homeostatic process GO:0032844 182 0.120
purine nucleotide catabolic process GO:0006195 211 0.120
negative regulation of viral induced cytoplasmic pattern recognition receptor signaling pathway GO:0039532 2 0.118
negative regulation of rig i signaling pathway GO:0039536 2 0.116
histone acetylation GO:0016573 41 0.113
movement in host environment GO:0052126 15 0.107
regulation of intracellular transport GO:0032386 159 0.107
regulation of cd8 positive alpha beta t cell proliferation GO:2000564 1 0.106
internal protein amino acid acetylation GO:0006475 42 0.104
negative regulation of protein metabolic process GO:0051248 282 0.104
myeloid cell differentiation GO:0030099 233 0.102
epithelial tube morphogenesis GO:0060562 303 0.102
regulation of cellular catabolic process GO:0031329 242 0.102
autophagy GO:0006914 45 0.097
interferon alpha production GO:0032607 7 0.097
macromolecule catabolic process GO:0009057 281 0.095
skin development GO:0043588 220 0.095
protein acylation GO:0043543 64 0.094
t helper 17 cell differentiation GO:0072539 7 0.094
regulation of defense response to virus GO:0050688 18 0.093
Human
regulation of myd88 independent toll like receptor signaling pathway GO:0034127 1 0.093
guanosine containing compound metabolic process GO:1901068 144 0.084
regulation of type i interferon mediated signaling pathway GO:0060338 7 0.083
negative regulation of response to biotic stimulus GO:0002832 10 0.082
Human
adhesion of symbiont to host GO:0044406 8 0.081
cellular protein catabolic process GO:0044257 155 0.079
protein import GO:0017038 101 0.079
erythrocyte differentiation GO:0030218 88 0.076
cellular macromolecule catabolic process GO:0044265 206 0.076
negative regulation of glial cell proliferation GO:0060253 4 0.076
neutrophil mediated killing of gram negative bacterium GO:0070945 4 0.075
regulation of protein targeting GO:1903533 61 0.074
myoblast differentiation involved in skeletal muscle regeneration GO:0014835 3 0.074
response to dsrna GO:0043331 30 0.074
Human
hair follicle cell proliferation GO:0071335 3 0.073
cd4 positive alpha beta t cell cytokine production GO:0035743 4 0.072
spleen development GO:0048536 39 0.070
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.069
cellular response to molecule of bacterial origin GO:0071219 83 0.068
chromatin organization GO:0006325 206 0.068
regulation of cell motility GO:2000145 236 0.068
limb development GO:0060173 166 0.066
positive regulation of viral genome replication GO:0045070 2 0.066
Human
gtp metabolic process GO:0046039 144 0.065
cellular response to type i interferon GO:0071357 10 0.065
Human
positive regulation of mapk cascade GO:0043410 170 0.063
regulation of intracellular protein transport GO:0033157 82 0.062
immune response activating signal transduction GO:0002757 116 0.061
positive regulation of cytokine production GO:0001819 174 0.060
limb morphogenesis GO:0035108 149 0.060
organophosphate biosynthetic process GO:0090407 122 0.060
rna catabolic process GO:0006401 29 0.060
myelination in peripheral nervous system GO:0022011 19 0.059
guanosine containing compound catabolic process GO:1901069 144 0.058
protein import into nucleus GO:0006606 95 0.058
stem cell development GO:0048864 219 0.058
positive regulation of myelination GO:0031643 5 0.058
covalent chromatin modification GO:0016569 163 0.057
cardiac cell development GO:0055006 41 0.056
regulation of protein localization GO:0032880 231 0.056
hatching GO:0035188 4 0.054
entry into host cell GO:0030260 15 0.054
regulation of viral transcription GO:0046782 3 0.053
myotube differentiation GO:0014902 105 0.051
positive regulation of neutrophil mediated killing of symbiont cell GO:0070961 1 0.051
negative regulation of cytoplasmic transport GO:1903650 29 0.049
negative regulation of nervous system development GO:0051961 156 0.046
multicellular organismal signaling GO:0035637 91 0.046
regulation of cd8 positive alpha beta t cell activation GO:2001185 3 0.046
negative regulation of cell development GO:0010721 169 0.046
interferon beta biosynthetic process GO:0045350 4 0.045
alpha beta t cell differentiation GO:0046632 69 0.044
modification dependent protein catabolic process GO:0019941 133 0.044
muscle cell development GO:0055001 133 0.044
response to lipopolysaccharide GO:0032496 128 0.044
macromolecule methylation GO:0043414 120 0.044
homeostasis of number of cells GO:0048872 210 0.043
positive regulation of cellular component biogenesis GO:0044089 94 0.043
regulation of t helper 1 cell cytokine production GO:2000554 1 0.043
negative regulation of cellular component organization GO:0051129 194 0.042
entry into cell of other organism involved in symbiotic interaction GO:0051806 15 0.042
schwann cell differentiation GO:0014037 26 0.042
negative regulation of nlrp3 inflammasome complex assembly GO:1900226 2 0.042
cytoplasmic pattern recognition receptor signaling pathway GO:0002753 10 0.041
regulation of production of molecular mediator of immune response GO:0002700 65 0.041
spindle assembly GO:0051225 13 0.041
peptidyl lysine modification GO:0018205 77 0.041
leukocyte mediated immunity GO:0002443 174 0.041
regulation of nlrp3 inflammasome complex assembly GO:1900225 4 0.041
gland development GO:0048732 330 0.039
olfactory bulb interneuron differentiation GO:0021889 12 0.039
type 2 immune response GO:0042092 23 0.037
zygote asymmetric cell division GO:0010070 2 0.037
syncytium formation by plasma membrane fusion GO:0000768 42 0.036
striated muscle tissue development GO:0014706 293 0.035
regulation of protein modification by small protein conjugation or removal GO:1903320 57 0.035
nucleocytoplasmic transport GO:0006913 139 0.035
regulation of binding GO:0051098 111 0.035
Human
cellular response to biotic stimulus GO:0071216 92 0.035
branching morphogenesis of an epithelial tube GO:0048754 159 0.035
regulation of cell cycle GO:0051726 281 0.035
positive regulation of neutrophil mediated cytotoxicity GO:0070960 1 0.034
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.034
positive regulation of innate immune response GO:0045089 80 0.034
negative regulation of molecular function GO:0044092 258 0.033
Human
stem cell differentiation GO:0048863 268 0.033
negative regulation of intracellular signal transduction GO:1902532 167 0.033
negative regulation of immune effector process GO:0002698 55 0.033
Human
negative regulation of protein ubiquitination GO:0031397 19 0.033
sequestering of metal ion GO:0051238 19 0.033
regulation of protein ubiquitination GO:0031396 52 0.033
organelle assembly GO:0070925 177 0.032
regulation of interferon beta production GO:0032648 13 0.032
atp metabolic process GO:0046034 75 0.032
defense response to gram negative bacterium GO:0050829 28 0.032
regulation of biomineral tissue development GO:0070167 33 0.031
myotube cell development GO:0014904 60 0.031
skeletal muscle organ development GO:0060538 163 0.031
positive regulation of binding GO:0051099 49 0.030
production of mirnas involved in gene silencing by mirna GO:0035196 6 0.030
interferon gamma production GO:0032609 67 0.030
nucleotide biosynthetic process GO:0009165 78 0.030
transmission of nerve impulse GO:0019226 76 0.030
meiotic cell cycle process GO:1903046 77 0.030
regulation of toll like receptor 9 signaling pathway GO:0034163 3 0.030
regulation of leukocyte mediated immunity GO:0002703 104 0.029
inflammatory response GO:0006954 244 0.029
divalent inorganic cation homeostasis GO:0072507 138 0.029
positive regulation of production of molecular mediator of immune response GO:0002702 45 0.029
intracellular protein transport GO:0006886 204 0.029
Human
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.029
tooth mineralization GO:0034505 9 0.029
regulation of establishment of protein localization GO:0070201 181 0.029
organism emergence from protective structure GO:0071684 4 0.029
purine nucleoside monophosphate metabolic process GO:0009126 81 0.028
regulation of neutrophil mediated killing of symbiont cell GO:0070949 2 0.028
rna phosphodiester bond hydrolysis endonucleolytic GO:0090502 10 0.028
negative regulation of viral transcription GO:0032897 3 0.028
cellular response to lipopolysaccharide GO:0071222 77 0.028
regulation of cell migration GO:0030334 219 0.028
negative regulation of intracellular protein transport GO:0090317 27 0.028
neuronal action potential GO:0019228 54 0.028
protein catabolic process GO:0030163 221 0.028
syncytium formation GO:0006949 43 0.028
divalent metal ion transport GO:0070838 172 0.027
alpha beta t cell activation involved in immune response GO:0002287 31 0.027
nucleoside phosphate biosynthetic process GO:1901293 79 0.027
blood vessel morphogenesis GO:0048514 285 0.027
cellular metal ion homeostasis GO:0006875 151 0.027
cd4 positive alpha beta t cell activation GO:0035710 45 0.026
regulation of cytokine biosynthetic process GO:0042035 59 0.026
regulation of nucleocytoplasmic transport GO:0046822 73 0.026
lung development GO:0030324 164 0.026
regulation of autophagy GO:0010506 30 0.026
regulation of viral entry into host cell GO:0046596 12 0.025
ribonucleoside monophosphate metabolic process GO:0009161 80 0.025
cation transport GO:0006812 399 0.025
developmental maturation GO:0021700 193 0.025
appendage morphogenesis GO:0035107 149 0.025
ubiquitin dependent protein catabolic process GO:0006511 129 0.025
negative regulation of protein modification by small protein conjugation or removal GO:1903321 20 0.025
epidermis development GO:0008544 187 0.025
digestive system development GO:0055123 200 0.025
activation of immune response GO:0002253 138 0.025
negative regulation of leukocyte differentiation GO:1902106 51 0.025
protein oligomerization GO:0051259 67 0.025
dna metabolic process GO:0006259 303 0.025
skeletal system development GO:0001501 356 0.024
interaction with host GO:0051701 22 0.024
Human
cellular homeostasis GO:0019725 240 0.024
myd88 independent toll like receptor signaling pathway GO:0002756 3 0.024
peptidyl amino acid modification GO:0018193 336 0.024
negative regulation of protein transport GO:0051224 46 0.023
respiratory system development GO:0060541 190 0.023
response to molecule of bacterial origin GO:0002237 143 0.023
morphogenesis of a branching structure GO:0001763 203 0.023
toll like receptor signaling pathway GO:0002224 38 0.023
regulation of organelle organization GO:0033043 289 0.023
alpha beta t cell activation GO:0046631 91 0.023
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.023
regulation of mapk cascade GO:0043408 248 0.023
carbohydrate metabolic process GO:0005975 230 0.023
microtubule cytoskeleton organization GO:0000226 157 0.023
negative regulation of protein phosphorylation GO:0001933 126 0.023
cellular ketone metabolic process GO:0042180 84 0.023
striated muscle cell development GO:0055002 125 0.023
carbohydrate derivative biosynthetic process GO:1901137 183 0.023
regulation of lymphocyte activation GO:0051249 240 0.023
gene silencing GO:0016458 38 0.023
cellular amino acid metabolic process GO:0006520 103 0.023
single organism nuclear import GO:1902593 95 0.023
regulation of membrane potential GO:0042391 192 0.022
atp catabolic process GO:0006200 55 0.022
positive regulation of programmed cell death GO:0043068 218 0.022
action potential GO:0001508 78 0.022
central nervous system neuron differentiation GO:0021953 162 0.022
t cell lineage commitment GO:0002360 13 0.022
meiotic cell cycle GO:0051321 122 0.022
forebrain development GO:0030900 302 0.022
anion transport GO:0006820 177 0.022
connective tissue development GO:0061448 179 0.022
ensheathment of neurons GO:0007272 76 0.022
type i interferon biosynthetic process GO:0045351 9 0.022
cell type specific apoptotic process GO:0097285 268 0.021
negative regulation of protein modification process GO:0031400 163 0.021
regulation of system process GO:0044057 200 0.021
germ cell development GO:0007281 185 0.021
inner ear receptor cell development GO:0060119 39 0.021
cd4 positive alpha beta t cell differentiation involved in immune response GO:0002294 28 0.021
transmembrane transport GO:0055085 412 0.021
spinal cord development GO:0021510 81 0.021
protein polyubiquitination GO:0000209 33 0.021
maintenance of location GO:0051235 89 0.021
ossification GO:0001503 216 0.021
tumor necrosis factor superfamily cytokine production GO:0071706 51 0.021
cation homeostasis GO:0055080 212 0.021
microtubule based process GO:0007017 236 0.021
natural killer cell proliferation GO:0001787 3 0.021
negative regulation of phosphate metabolic process GO:0045936 184 0.021
peripheral nervous system development GO:0007422 53 0.021
leukocyte proliferation GO:0070661 172 0.021
positive regulation of interleukin 12 production GO:0032735 21 0.021
t cell differentiation GO:0030217 174 0.021
protein methylation GO:0006479 81 0.020
histone modification GO:0016570 159 0.020
regulation of gliogenesis GO:0014013 50 0.020
negative regulation of defense response GO:0031348 77 0.020
Human
regulation of neutrophil mediated killing of fungus GO:0070953 1 0.020
metal ion homeostasis GO:0055065 189 0.020
citrate metabolic process GO:0006101 3 0.020
regulation of cellular ketone metabolic process GO:0010565 66 0.020
respiratory tube development GO:0030323 167 0.020
endocytosis GO:0006897 168 0.020
sensory perception GO:0007600 245 0.020
methylation GO:0032259 134 0.020
multicellular organism growth GO:0035264 161 0.020
sequestering of calcium ion GO:0051208 18 0.020
protein sumoylation GO:0016925 14 0.020
organonitrogen compound biosynthetic process GO:1901566 192 0.019
cd4 positive or cd8 positive alpha beta t cell lineage commitment GO:0043369 8 0.019
regulation of dna binding GO:0051101 39 0.019
positive regulation of toll like receptor 9 signaling pathway GO:0034165 2 0.019
positive regulation of protein complex assembly GO:0031334 45 0.019
immunoglobulin mediated immune response GO:0016064 69 0.019
protein alkylation GO:0008213 81 0.019
appendage development GO:0048736 166 0.019
cellular lipid metabolic process GO:0044255 323 0.019
lipopolysaccharide mediated signaling pathway GO:0031663 25 0.019
positive regulation of actin nucleation GO:0051127 3 0.019
immunoglobulin production involved in immunoglobulin mediated immune response GO:0002381 43 0.019
adaptive immune response GO:0002250 155 0.019
regulation of muscle cell apoptotic process GO:0010660 17 0.019
positive regulation of neutrophil mediated killing of fungus GO:0070965 1 0.019
b cell mediated immunity GO:0019724 71 0.019
regulation of myelination GO:0031641 20 0.019
spermatogenesis GO:0007283 284 0.019
nerve development GO:0021675 67 0.019
positive regulation of myeloid cell differentiation GO:0045639 43 0.018
cardiocyte differentiation GO:0035051 87 0.018
glial cell differentiation GO:0010001 131 0.018
cell division GO:0051301 120 0.018
embryonic appendage morphogenesis GO:0035113 126 0.018
regulation of actin nucleation GO:0051125 4 0.018
regulation of response to wounding GO:1903034 189 0.018
positive regulation of thymocyte migration GO:2000412 2 0.018
regulation of syncytium formation by plasma membrane fusion GO:0060142 23 0.018
posttranscriptional gene silencing GO:0016441 10 0.018
cellular amine metabolic process GO:0044106 44 0.018
regulation of protein localization to nucleus GO:1900180 60 0.018
embryonic limb morphogenesis GO:0030326 126 0.017
nucleoside monophosphate metabolic process GO:0009123 85 0.017
regulation of neuron differentiation GO:0045664 281 0.017
purine nucleotide biosynthetic process GO:0006164 65 0.017
regulation of interleukin 12 production GO:0032655 30 0.017
oligodendrocyte differentiation GO:0048709 53 0.017
mrna stabilization GO:0048255 9 0.017
regulation of type 2 immune response GO:0002828 18 0.017
gliogenesis GO:0042063 141 0.017
negative regulation of interferon beta biosynthetic process GO:0045358 1 0.017
angiogenesis GO:0001525 201 0.017
negative regulation of schwann cell proliferation GO:0010626 1 0.017
regulation of adaptive immune response GO:0002819 90 0.017
posttranscriptional regulation of gene expression GO:0010608 155 0.017
production of molecular mediator of immune response GO:0002440 103 0.017
regulation of secretion by cell GO:1903530 249 0.017
cellular response to organic cyclic compound GO:0071407 87 0.017
Human
regulation of cellular amino acid metabolic process GO:0006521 5 0.016
signal transduction involved in dna integrity checkpoint GO:0072401 3 0.016
protein secretion GO:0009306 111 0.016
mechanoreceptor differentiation GO:0042490 67 0.016
mesenchyme development GO:0060485 152 0.016
regulation of vasculature development GO:1901342 88 0.016
regulation of cell activation GO:0050865 289 0.016
regulation of lymphocyte differentiation GO:0045619 107 0.016
regulation of innate immune response GO:0045088 91 0.016
regulation of tumor necrosis factor production GO:0032680 49 0.016
monocarboxylic acid metabolic process GO:0032787 191 0.016
regulation of epithelial cell proliferation GO:0050678 141 0.016
negative regulation of phosphorylation GO:0042326 166 0.016
regulation of myeloid cell differentiation GO:0045637 96 0.016
cellular chemical homeostasis GO:0055082 215 0.015
leukocyte migration GO:0050900 124 0.015
epidermis morphogenesis GO:0048730 33 0.015
cytokine mediated signaling pathway GO:0019221 115 0.015
telencephalon development GO:0021537 186 0.015
negative regulation of growth GO:0045926 99 0.015
renal tubule development GO:0061326 87 0.015
positive regulation of nervous system development GO:0051962 221 0.015
muscle cell apoptotic process GO:0010657 18 0.015
regulation of striated muscle cell differentiation GO:0051153 81 0.015
negative regulation of immune system process GO:0002683 209 0.015
Human
sensory organ morphogenesis GO:0090596 242 0.015
negative regulation of regulatory t cell differentiation GO:0045590 2 0.015
chemokine production GO:0032602 34 0.015
cerebral cortex development GO:0021987 86 0.015
regulation of protein binding GO:0043393 60 0.015
Human
regulation of ossification GO:0030278 112 0.015
hematopoietic progenitor cell differentiation GO:0002244 143 0.015
leukocyte activation involved in immune response GO:0002366 126 0.015
cd4 positive alpha beta t cell differentiation GO:0043367 41 0.015
pallium development GO:0021543 120 0.015
compound eye development GO:0048749 1 0.015
epithelial cell proliferation GO:0050673 174 0.015
positive regulation of eosinophil migration GO:2000418 2 0.015
neutrophil mediated killing of fungus GO:0070947 3 0.015
negative regulation of lymphocyte activation GO:0051250 91 0.015
small gtpase mediated signal transduction GO:0007264 97 0.015
cellular component assembly involved in morphogenesis GO:0010927 139 0.015
pyrimidine containing compound catabolic process GO:0072529 3 0.015
negative regulation of gliogenesis GO:0014014 23 0.014
regulation of leukocyte differentiation GO:1902105 159 0.014
hair follicle morphogenesis GO:0031069 29 0.014
rna interference GO:0016246 2 0.014
ribonucleoside monophosphate catabolic process GO:0009158 57 0.014
purine nucleoside monophosphate catabolic process GO:0009128 58 0.014
positive regulation of camp mediated signaling GO:0043950 3 0.014
cellular response to dsrna GO:0071359 12 0.014
Human
rna phosphodiester bond hydrolysis GO:0090501 19 0.014
actin cytoskeleton organization GO:0030036 220 0.014
positive regulation of ossification GO:0045778 47 0.014
heart morphogenesis GO:0003007 178 0.014
axon ensheathment GO:0008366 76 0.014
protein maturation GO:0051604 176 0.014
positive regulation of kinase activity GO:0033674 155 0.014
negative regulation of innate immune response GO:0045824 17 0.014
pyroptosis GO:0070269 8 0.014
viral release from host cell GO:0019076 6 0.014
regulation of secretion GO:0051046 274 0.013
regulation of protein import into nucleus GO:0042306 52 0.013
interferon gamma mediated signaling pathway GO:0060333 5 0.013
circadian rhythm GO:0007623 114 0.013
male gamete generation GO:0048232 285 0.013
regulation of neuron death GO:1901214 134 0.013
peptidyl lysine methylation GO:0018022 29 0.013
protein localization to organelle GO:0033365 185 0.013
second messenger mediated signaling GO:0019932 73 0.013
positive regulation of killing of cells of other organism GO:0051712 3 0.013
asymmetric cell division GO:0008356 8 0.013
regulation of protein complex assembly GO:0043254 83 0.013
mammary gland epithelium development GO:0061180 65 0.013
immunoglobulin production GO:0002377 73 0.013
keratinocyte proliferation GO:0043616 21 0.013

Ifit1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org