Mus musculus

118 known processes

Atf4

activating transcription factor 4

(Aliases: MGC96460,TAXREB67,C/ATF,Atf-4,CREB2)

Atf4 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
response to endoplasmic reticulum stress GO:0034976 53 0.998
positive regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032436 23 0.801
fatty acid biosynthetic process GO:0006633 41 0.796
cellular ketone metabolic process GO:0042180 84 0.786
regulation of fatty acid biosynthetic process GO:0042304 12 0.761
negative regulation of fatty acid metabolic process GO:0045922 10 0.741
carbohydrate metabolic process GO:0005975 230 0.686
negative regulation of fat cell differentiation GO:0045599 36 0.653
apoptotic signaling pathway GO:0097190 306 0.649
generation of precursor metabolites and energy GO:0006091 103 0.640
regulation of ligase activity GO:0051340 10 0.602
regulation of protein kinase activity GO:0045859 232 0.593
positive regulation of ubiquitin protein transferase activity GO:0051443 4 0.577
regulation of protein ubiquitination involved in ubiquitin dependent protein catabolic process GO:2000058 14 0.566
intrinsic apoptotic signaling pathway GO:0097193 132 0.565
protein modification by small protein conjugation GO:0032446 187 0.544
regulation of cellular ketone metabolic process GO:0010565 66 0.543
regulation of fatty acid metabolic process GO:0019217 28 0.540
carbohydrate transport GO:0008643 62 0.534
regulation of fat cell differentiation GO:0045598 81 0.529
ubiquitin dependent protein catabolic process GO:0006511 129 0.526
regulation of kinase activity GO:0043549 249 0.525
proteasomal protein catabolic process GO:0010498 98 0.486
positive regulation of protein ubiquitination involved in ubiquitin dependent protein catabolic process GO:2000060 8 0.483
positive regulation of protein modification process GO:0031401 299 0.482
mapk cascade GO:0000165 281 0.480
regulation of transferase activity GO:0051338 263 0.467
respiratory system development GO:0060541 190 0.459
organic acid biosynthetic process GO:0016053 86 0.459
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.452
multicellular organism growth GO:0035264 161 0.443
Mouse
negative regulation of phosphorylation GO:0042326 166 0.439
regulation of ubiquitin protein transferase activity GO:0051438 7 0.429
negative regulation of phosphorus metabolic process GO:0010563 184 0.426
carboxylic acid biosynthetic process GO:0046394 86 0.421
cellular macromolecule catabolic process GO:0044265 206 0.418
fat cell differentiation GO:0045444 160 0.416
positive regulation of transferase activity GO:0051347 167 0.410
cellular protein catabolic process GO:0044257 155 0.403
modification dependent protein catabolic process GO:0019941 133 0.395
regulation of mitotic cell cycle GO:0007346 126 0.395
protein modification by small protein conjugation or removal GO:0070647 207 0.391
negative regulation of molecular function GO:0044092 258 0.388
regulation of organelle organization GO:0033043 289 0.383
protein ubiquitination GO:0016567 171 0.382
cellular lipid metabolic process GO:0044255 323 0.381
response to organonitrogen compound GO:0010243 246 0.378
modification dependent macromolecule catabolic process GO:0043632 133 0.378
negative regulation of lipid metabolic process GO:0045833 30 0.374
positive regulation of cellular catabolic process GO:0031331 148 0.373
cellular carbohydrate metabolic process GO:0044262 119 0.370
cellular response to hormone stimulus GO:0032870 150 0.368
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.356
positive regulation of cellular protein catabolic process GO:1903364 34 0.352
fatty acid metabolic process GO:0006631 121 0.349
positive regulation of protein ubiquitination GO:0031398 27 0.347
regulation of protein serine threonine kinase activity GO:0071900 157 0.344
monocarboxylic acid metabolic process GO:0032787 191 0.344
positive regulation of proteolysis involved in cellular protein catabolic process GO:1903052 31 0.339
cellular response to peptide GO:1901653 92 0.334
energy reserve metabolic process GO:0006112 39 0.333
regulation of glucose transport GO:0010827 32 0.321
regulation of cell cycle GO:0051726 281 0.319
response to peptide GO:1901652 136 0.317
response to molecule of bacterial origin GO:0002237 143 0.316
regulation of binding GO:0051098 111 0.316
regulation of map kinase activity GO:0043405 120 0.313
hexose transport GO:0008645 56 0.312
cellular response to insulin stimulus GO:0032869 78 0.304
protein catabolic process GO:0030163 221 0.299
response to lipopolysaccharide GO:0032496 128 0.298
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 56 0.295
negative regulation of cellular component organization GO:0051129 194 0.292
negative regulation of phosphate metabolic process GO:0045936 184 0.290
monocarboxylic acid biosynthetic process GO:0072330 61 0.285
response to peptide hormone GO:0043434 127 0.283
lipid biosynthetic process GO:0008610 179 0.275
oxidation reduction process GO:0055114 342 0.272
respiratory gaseous exchange GO:0007585 43 0.271
small molecule biosynthetic process GO:0044283 132 0.265
lung development GO:0030324 164 0.264
glucose transport GO:0015758 56 0.262
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.255
glucan metabolic process GO:0044042 32 0.253
macromolecule catabolic process GO:0009057 281 0.253
negative regulation of transferase activity GO:0051348 85 0.253
cellular response to peptide hormone stimulus GO:0071375 92 0.252
energy derivation by oxidation of organic compounds GO:0015980 77 0.251
respiratory tube development GO:0030323 167 0.250
negative regulation of kinase activity GO:0033673 81 0.247
positive regulation of protein modification by small protein conjugation or removal GO:1903322 30 0.247
regulation of mapk cascade GO:0043408 248 0.245
regulation of cell division GO:0051302 76 0.237
negative regulation of nuclear division GO:0051784 19 0.230
negative regulation of protein phosphorylation GO:0001933 126 0.227
leukocyte differentiation GO:0002521 342 0.223
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 40 0.223
negative regulation of cellular protein metabolic process GO:0032269 247 0.221
mitotic cell cycle process GO:1903047 159 0.218
mitotic cell cycle GO:0000278 195 0.216
respiratory system process GO:0003016 25 0.213
regulation of protein binding GO:0043393 60 0.213
cellular response to organonitrogen compound GO:0071417 145 0.212
regulation of cellular catabolic process GO:0031329 242 0.211
negative regulation of protein metabolic process GO:0051248 282 0.210
regulation of protein modification by small protein conjugation or removal GO:1903320 57 0.200
response to insulin GO:0032868 100 0.199
cell division GO:0051301 120 0.199
regulation of cellular protein catabolic process GO:1903362 61 0.197
positive regulation of proteolysis GO:0045862 85 0.188
glycogen metabolic process GO:0005977 32 0.187
cellular glucan metabolic process GO:0006073 32 0.185
lung alveolus development GO:0048286 45 0.185
amine metabolic process GO:0009308 45 0.179
polysaccharide metabolic process GO:0005976 39 0.178
negative regulation of protein modification process GO:0031400 163 0.176
mitotic nuclear division GO:0007067 48 0.168
regulation of proteasomal protein catabolic process GO:0061136 46 0.161
cellular response to cytokine stimulus GO:0071345 189 0.160
negative regulation of cell cycle GO:0045786 123 0.158
regulation of nuclear division GO:0051783 56 0.156
cellular amine metabolic process GO:0044106 44 0.153
cellular polysaccharide metabolic process GO:0044264 38 0.152
myeloid leukocyte differentiation GO:0002573 119 0.147
monosaccharide transport GO:0015749 58 0.145
positive regulation of protein binding GO:0032092 29 0.144
regulation of cell cycle process GO:0010564 160 0.142
regulation of protein catabolic process GO:0042176 108 0.141
organelle fission GO:0048285 170 0.140
cellular amino acid metabolic process GO:0006520 103 0.139
regulation of protein ubiquitination GO:0031396 52 0.135
positive regulation of protein catabolic process GO:0045732 60 0.131
positive regulation of binding GO:0051099 49 0.130
negative regulation of organelle organization GO:0010639 90 0.128
regulation of lipid biosynthetic process GO:0046890 54 0.120
regulation of cellular amino acid metabolic process GO:0006521 5 0.120
cytokine production GO:0001816 319 0.119
peptidyl amino acid modification GO:0018193 336 0.118
neuron apoptotic process GO:0051402 142 0.113
innate immune response GO:0045087 157 0.110
protein ubiquitination involved in ubiquitin dependent protein catabolic process GO:0042787 25 0.108
myeloid cell differentiation GO:0030099 233 0.101
negative regulation of mitotic cell cycle GO:0045930 58 0.099
striated muscle tissue development GO:0014706 293 0.099
regulation of leukocyte differentiation GO:1902105 159 0.094
t cell activation GO:0042110 289 0.094
covalent chromatin modification GO:0016569 163 0.093
myosin filament organization GO:0031033 3 0.090
translation GO:0006412 93 0.089
regulation of cellular response to stress GO:0080135 159 0.086
Human
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.085
hexose metabolic process GO:0019318 98 0.084
regulation of cellular amine metabolic process GO:0033238 20 0.083
response to organic cyclic compound GO:0014070 198 0.082
glucose metabolic process GO:0006006 92 0.079
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.077
regulation of myeloid leukocyte differentiation GO:0002761 58 0.076
camera type eye development GO:0043010 266 0.075
lymphocyte differentiation GO:0030098 242 0.075
regulation of cytokine production GO:0001817 266 0.074
positive regulation of cellular amine metabolic process GO:0033240 5 0.072
cell type specific apoptotic process GO:0097285 268 0.072
er nucleus signaling pathway GO:0006984 27 0.071
muscle tissue development GO:0060537 308 0.071
positive regulation of protein phosphorylation GO:0001934 242 0.070
nuclear division GO:0000280 158 0.070
germ cell development GO:0007281 185 0.069
response to unfolded protein GO:0006986 21 0.068
regulation of neuron apoptotic process GO:0043523 122 0.068
regulation of mitosis GO:0007088 29 0.067
regulation of cell migration GO:0030334 219 0.067
negative regulation of fatty acid biosynthetic process GO:0045717 7 0.066
positive regulation of cell death GO:0010942 224 0.065
skeletal system development GO:0001501 356 0.065
chromatin modification GO:0016568 187 0.063
positive regulation of cytokine production GO:0001819 174 0.063
negative regulation of cell division GO:0051782 24 0.063
positive regulation of cell motility GO:2000147 116 0.060
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.059
neuron death GO:0070997 154 0.059
sensory organ morphogenesis GO:0090596 242 0.058
t cell differentiation GO:0030217 174 0.057
reactive oxygen species metabolic process GO:0072593 84 0.057
cytoplasmic transport GO:0016482 234 0.054
wound healing GO:0042060 157 0.053
regulation of neuron differentiation GO:0045664 281 0.053
nucleobase containing small molecule metabolic process GO:0055086 352 0.051
response to inorganic substance GO:0010035 96 0.051
cation transport GO:0006812 399 0.050
activation of mapkkk activity GO:0000185 1 0.050
axonogenesis GO:0007409 274 0.050
circadian rhythm GO:0007623 114 0.049
neuromuscular process GO:0050905 99 0.049
chromatin organization GO:0006325 206 0.048
cellular response to topologically incorrect protein GO:0035967 25 0.048
apoptotic mitochondrial changes GO:0008637 48 0.047
dna metabolic process GO:0006259 303 0.047
positive regulation of protein kinase activity GO:0045860 144 0.047
regulation of defense response GO:0031347 233 0.046
nitrogen compound transport GO:0071705 271 0.046
hexose biosynthetic process GO:0019319 39 0.045
cellular chemical homeostasis GO:0055082 215 0.045
response to extracellular stimulus GO:0009991 127 0.045
regulation of cell motility GO:2000145 236 0.044
canonical wnt signaling pathway GO:0060070 130 0.044
positive regulation of apoptotic process GO:0043065 217 0.043
skeletal muscle organ development GO:0060538 163 0.043
regulation of transcription from rna polymerase ii promoter in response to stress GO:0043618 8 0.043
regulation of protein localization GO:0032880 231 0.042
positive regulation of transcription from rna polymerase ii promoter in response to stress GO:0036003 3 0.042
regulation of membrane potential GO:0042391 192 0.042
response to nutrient levels GO:0031667 109 0.042
ion transmembrane transport GO:0034220 361 0.040
regulation of secretion by cell GO:1903530 249 0.040
cellular response to dna damage stimulus GO:0006974 207 0.040
regulation of cytoskeleton organization GO:0051493 122 0.040
histone modification GO:0016570 159 0.040
regulation of ossification GO:0030278 112 0.039
nucleocytoplasmic transport GO:0006913 139 0.039
skeletal muscle cell differentiation GO:0035914 66 0.039
protein targeting GO:0006605 143 0.039
cellular response to lipid GO:0071396 145 0.039
regulation of hormone levels GO:0010817 211 0.038
response to reactive oxygen species GO:0000302 56 0.038
purine nucleotide metabolic process GO:0006163 302 0.038
compound eye development GO:0048749 1 0.038
regulation of multi organism process GO:0043900 111 0.038
muscle cell differentiation GO:0042692 261 0.038
ossification GO:0001503 216 0.037
positive regulation of kinase activity GO:0033674 155 0.037
regulation of lymphocyte activation GO:0051249 240 0.037
regulation of hydrolase activity GO:0051336 246 0.036
purine nucleoside metabolic process GO:0042278 241 0.036
regulation of ion transport GO:0043269 215 0.036
organic anion transport GO:0015711 137 0.036
wnt signaling pathway GO:0016055 188 0.035
monosaccharide metabolic process GO:0005996 106 0.035
cellular homeostasis GO:0019725 240 0.035
myeloid leukocyte activation GO:0002274 83 0.034
microtubule based process GO:0007017 236 0.034
cell growth GO:0016049 130 0.034
ras protein signal transduction GO:0007265 77 0.034
developmental cell growth GO:0048588 84 0.034
transmembrane transport GO:0055085 412 0.034
membrane organization GO:0061024 245 0.034
negative regulation of neuron death GO:1901215 98 0.034
Human
negative regulation of neuron apoptotic process GO:0043524 92 0.033
epidermis development GO:0008544 187 0.033
glucose homeostasis GO:0042593 128 0.033
endoplasmic reticulum unfolded protein response GO:0030968 19 0.033
organonitrogen compound biosynthetic process GO:1901566 192 0.033
regulation of wnt signaling pathway GO:0030111 123 0.033
peptidyl serine phosphorylation GO:0018105 74 0.033
embryonic organ morphogenesis GO:0048562 276 0.033
regulation of apoptotic signaling pathway GO:2001233 197 0.033
kidney development GO:0001822 213 0.033
cellular response to gamma radiation GO:0071480 4 0.032
protein localization to organelle GO:0033365 185 0.032
renal system development GO:0072001 225 0.032
nucleotide metabolic process GO:0009117 332 0.032
regulation of myeloid cell differentiation GO:0045637 96 0.032
response to acid chemical GO:0001101 111 0.031
regulation of cell activation GO:0050865 289 0.031
regulation of neuron death GO:1901214 134 0.031
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.031
epithelial cell proliferation GO:0050673 174 0.031
divalent inorganic cation transport GO:0072511 178 0.031
g protein coupled receptor signaling pathway GO:0007186 243 0.031
jnk cascade GO:0007254 72 0.031
peptidyl serine modification GO:0018209 83 0.031
purine containing compound metabolic process GO:0072521 311 0.031
male gamete generation GO:0048232 285 0.031
amino acid activation GO:0043038 1 0.031
fibroblast proliferation GO:0048144 35 0.030
negative regulation of cellular amine metabolic process GO:0033239 1 0.030
nucleoside phosphate metabolic process GO:0006753 338 0.030
actin cytoskeleton organization GO:0030036 220 0.030
regulation of antimicrobial humoral response GO:0002759 3 0.029
negative regulation of transcription from rna polymerase ii promoter in response to stress GO:0097201 1 0.029
establishment of protein localization to organelle GO:0072594 118 0.029
protein hydroxylation GO:0018126 4 0.029
interspecies interaction between organisms GO:0044419 83 0.029
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.029
osteoclast differentiation GO:0030316 62 0.029
cellular response to antibiotic GO:0071236 4 0.029
hindbrain development GO:0030902 128 0.029
maintenance of location GO:0051235 89 0.029
purine ribonucleoside metabolic process GO:0046128 241 0.028
blood circulation GO:0008015 195 0.028
interleukin 8 production GO:0032637 4 0.028
aromatic compound catabolic process GO:0019439 286 0.028
stem cell development GO:0048864 219 0.028
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.028
regulation of interleukin 8 production GO:0032677 3 0.027
protein localization to nucleus GO:0034504 121 0.027
regulation of chromosome organization GO:0033044 83 0.027
intracellular protein transport GO:0006886 204 0.027
positive regulation of cell migration GO:0030335 109 0.027
ribose phosphate metabolic process GO:0019693 291 0.027
central nervous system neuron differentiation GO:0021953 162 0.027
Mouse
carbohydrate homeostasis GO:0033500 128 0.027
posttranscriptional regulation of gene expression GO:0010608 155 0.027
negative regulation of nervous system development GO:0051961 156 0.027
regulation of nucleotide metabolic process GO:0006140 169 0.027
inflammatory response GO:0006954 244 0.027
microtubule cytoskeleton organization GO:0000226 157 0.027
circulatory system process GO:0003013 197 0.027
response to growth factor GO:0070848 198 0.027
nuclear transport GO:0051169 139 0.027
regulation of cell growth GO:0001558 91 0.027
organonitrogen compound catabolic process GO:1901565 264 0.026
spermatogenesis GO:0007283 284 0.026
cellular response to oxidative stress GO:0034599 76 0.026
Human
rhythmic process GO:0048511 174 0.026
positive regulation of hydrolase activity GO:0051345 148 0.026
neuromuscular process controlling balance GO:0050885 59 0.026
positive regulation of myeloid leukocyte differentiation GO:0002763 26 0.026
gluconeogenesis GO:0006094 39 0.026
p38mapk cascade GO:0038066 4 0.026
cation transmembrane transport GO:0098655 266 0.025
peptidyl tyrosine modification GO:0018212 145 0.025
regulation of lymphocyte differentiation GO:0045619 107 0.025
positive regulation of leukocyte differentiation GO:1902107 86 0.025
regulation of dna templated transcription in response to stress GO:0043620 9 0.025
stress activated mapk cascade GO:0051403 80 0.025
gland development GO:0048732 330 0.025
ribonucleotide catabolic process GO:0009261 208 0.025
amino acid transmembrane transport GO:0003333 37 0.025
synaptic transmission GO:0007268 329 0.025
macromolecule methylation GO:0043414 120 0.025
urogenital system development GO:0001655 261 0.025
regulation of cell projection organization GO:0031344 206 0.025
regulation of inflammatory response GO:0050727 147 0.025
blood vessel morphogenesis GO:0048514 285 0.025
norepinephrine transport GO:0015874 2 0.024
regulation of cyclin dependent protein serine threonine kinase activity GO:0000079 16 0.024
cellular response to extracellular stimulus GO:0031668 81 0.024
regulation of reactive oxygen species metabolic process GO:2000377 40 0.024
metencephalon development GO:0022037 89 0.024
locomotory behavior GO:0007626 195 0.024
sequestering of calcium ion GO:0051208 18 0.024
response to starvation GO:0042594 65 0.024
sensory perception GO:0007600 245 0.024
regulation of nucleoside metabolic process GO:0009118 130 0.024
divalent metal ion transport GO:0070838 172 0.024
regulation of cell size GO:0008361 72 0.024
regulation of system process GO:0044057 200 0.024
cellular nitrogen compound catabolic process GO:0044270 280 0.024
negative regulation of immune system process GO:0002683 209 0.024
positive regulation of transcription from rna polymerase i promoter GO:0045943 3 0.024
transforming growth factor beta2 production GO:0032906 2 0.024
reactive nitrogen species metabolic process GO:2001057 0 0.024
forebrain development GO:0030900 302 0.023
Mouse
developmental growth involved in morphogenesis GO:0060560 138 0.023
rna processing GO:0006396 105 0.023
regulation of peptidase activity GO:0052547 96 0.023
skeletal system morphogenesis GO:0048705 203 0.023
small gtpase mediated signal transduction GO:0007264 97 0.023
positive regulation of nucleotide metabolic process GO:0045981 114 0.023
amino acid transport GO:0006865 61 0.022
ribonucleotide metabolic process GO:0009259 291 0.022
angiogenesis GO:0001525 201 0.022
peptidyl tyrosine phosphorylation GO:0018108 143 0.022
extrinsic apoptotic signaling pathway GO:0097191 126 0.022
regulation of osteoclast differentiation GO:0045670 36 0.022
eye photoreceptor cell development GO:0042462 31 0.022
microglial cell activation GO:0001774 3 0.022
regulation of secretion GO:0051046 274 0.022
regulation of lipid metabolic process GO:0019216 118 0.022
chemotaxis GO:0006935 247 0.022
adult behavior GO:0030534 135 0.022
regulation of proteolysis GO:0030162 164 0.022
hormone secretion GO:0046879 128 0.022
peptide transport GO:0015833 133 0.022
regulation of neuron projection development GO:0010975 169 0.022
cellular response to nutrient levels GO:0031669 64 0.022
t cell differentiation in thymus GO:0033077 77 0.022
negative regulation of growth GO:0045926 99 0.022
ribonucleoside catabolic process GO:0042454 206 0.022
organic cyclic compound catabolic process GO:1901361 295 0.022
carbohydrate derivative biosynthetic process GO:1901137 183 0.021
metal ion homeostasis GO:0055065 189 0.021
single organism nuclear import GO:1902593 95 0.021
carbohydrate derivative catabolic process GO:1901136 231 0.021
ear development GO:0043583 200 0.021
negative regulation of intracellular signal transduction GO:1902532 167 0.021
negative regulation of cell proliferation GO:0008285 296 0.021
purine ribonucleotide metabolic process GO:0009150 290 0.021
female gamete generation GO:0007292 74 0.021
protein import GO:0017038 101 0.021
labyrinthine layer development GO:0060711 49 0.021
cellular response to inorganic substance GO:0071241 37 0.021
connective tissue development GO:0061448 179 0.021
protein secretion GO:0009306 111 0.021
calcium ion transport GO:0006816 159 0.021
rho protein signal transduction GO:0007266 32 0.021
alpha beta t cell differentiation GO:0046632 69 0.021
cognition GO:0050890 149 0.021
purine nucleoside triphosphate metabolic process GO:0009144 226 0.020
digestive tract development GO:0048565 190 0.020
response to metal ion GO:0010038 47 0.020
development of primary sexual characteristics GO:0045137 143 0.020
telencephalon development GO:0021537 186 0.020
Mouse
retina development in camera type eye GO:0060041 119 0.020
regulation of cellular component size GO:0032535 121 0.020
trna metabolic process GO:0006399 11 0.020
regulation of cyclin dependent protein serine threonine kinase activity involved in g2 m transition of mitotic cell cycle GO:0031660 1 0.020
heart morphogenesis GO:0003007 178 0.020
circadian regulation of gene expression GO:0032922 48 0.020
placenta development GO:0001890 140 0.020
divalent inorganic cation homeostasis GO:0072507 138 0.020
glycosyl compound metabolic process GO:1901657 246 0.020
positive regulation of neuron differentiation GO:0045666 141 0.020
cellular calcium ion homeostasis GO:0006874 119 0.020
carbohydrate biosynthetic process GO:0016051 74 0.020
steroid metabolic process GO:0008202 119 0.019
leukocyte proliferation GO:0070661 172 0.019
blastocyst development GO:0001824 80 0.019
learning or memory GO:0007611 148 0.019
stress activated protein kinase signaling cascade GO:0031098 81 0.019
regulation of establishment of protein localization GO:0070201 181 0.019
purine containing compound catabolic process GO:0072523 213 0.019
response to amino acid GO:0043200 37 0.019
positive regulation of myeloid cell differentiation GO:0045639 43 0.019
response to topologically incorrect protein GO:0035966 25 0.019
phagocytosis GO:0006909 66 0.019
leukocyte mediated immunity GO:0002443 174 0.019
l amino acid transport GO:0015807 32 0.019
monosaccharide biosynthetic process GO:0046364 44 0.019
anion transmembrane transport GO:0098656 71 0.019
negative regulation of nik nf kappab signaling GO:1901223 2 0.019
b cell activation GO:0042113 161 0.019
homeostasis of number of cells GO:0048872 210 0.019
response to interferon gamma GO:0034341 34 0.019
regulation of response to wounding GO:1903034 189 0.019
cellular metal ion homeostasis GO:0006875 151 0.019
purine ribonucleotide catabolic process GO:0009154 208 0.019
cell adhesion GO:0007155 329 0.019
negative regulation of multi organism process GO:0043901 68 0.019
eye photoreceptor cell differentiation GO:0001754 41 0.018
lateral inhibition GO:0046331 1 0.018
photoreceptor cell differentiation GO:0046530 52 0.018
trna aminoacylation for protein translation GO:0006418 1 0.018
positive regulation of secretion GO:0051047 130 0.018
heterocycle catabolic process GO:0046700 280 0.018
protein import into nucleus GO:0006606 95 0.018
ribonucleoside metabolic process GO:0009119 245 0.018
response to oxygen levels GO:0070482 62 0.018
nuclear import GO:0051170 95 0.018
nucleoside triphosphate metabolic process GO:0009141 230 0.018
regulation of action potential GO:0098900 4 0.018
placenta blood vessel development GO:0060674 31 0.018
sequestering of metal ion GO:0051238 19 0.018
regulation of purine nucleotide metabolic process GO:1900542 169 0.018
positive regulation of nucleoside metabolic process GO:0045979 91 0.018
developmental maturation GO:0021700 193 0.018
regulation of homeostatic process GO:0032844 182 0.018
regulation of cysteine type endopeptidase activity GO:2000116 65 0.018
response to interleukin 1 GO:0070555 11 0.018
cytokine mediated signaling pathway GO:0019221 115 0.018
positive regulation of cell development GO:0010720 237 0.018
regionalization GO:0003002 337 0.018
reactive oxygen species biosynthetic process GO:1903409 8 0.018
regulation of body fluid levels GO:0050878 162 0.018
negative regulation of neuron differentiation GO:0045665 101 0.018
positive regulation of organelle organization GO:0010638 128 0.018
viral life cycle GO:0019058 36 0.018
regulation of muscle tissue development GO:1901861 97 0.017
response to radiation GO:0009314 165 0.017
protein processing GO:0016485 163 0.017
response to drug GO:0042493 75 0.017
glycoprotein metabolic process GO:0009100 116 0.017
ribonucleoside triphosphate metabolic process GO:0009199 220 0.017
i kappab kinase nf kappab signaling GO:0007249 85 0.017
intrinsic apoptotic signaling pathway in response to dna damage GO:0008630 57 0.017
molting cycle GO:0042303 90 0.017
regulation of fibroblast proliferation GO:0048145 34 0.017
positive regulation of mapk cascade GO:0043410 170 0.017
bmp signaling pathway GO:0030509 93 0.017
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.017
purine nucleoside catabolic process GO:0006152 205 0.017
response to steroid hormone GO:0048545 56 0.017
positive regulation of interleukin 8 production GO:0032757 2 0.017
norepinephrine secretion GO:0048243 2 0.017

Atf4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.127
nervous system disease DOID:863 0 0.127
neuropathy DOID:870 0 0.127
neuromuscular disease DOID:440 0 0.063
charcot marie tooth disease DOID:10595 0 0.063
cancer DOID:162 0 0.037
disease of cellular proliferation DOID:14566 0 0.037
organ system cancer DOID:0050686 0 0.037
musculoskeletal system disease DOID:17 0 0.023
immune system disease DOID:2914 0 0.022
muscular disease DOID:0080000 0 0.020
charcot marie tooth disease type 2 DOID:0050539 0 0.020
muscle tissue disease DOID:66 0 0.018
hematopoietic system disease DOID:74 0 0.017