Mus musculus

98 known processes

Atf3

activating transcription factor 3

(Aliases: LRG-21)

Atf3 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
regulation of cyclin dependent protein serine threonine kinase activity involved in g2 m transition of mitotic cell cycle GO:0031660 1 0.803
Fly
cytokine production GO:0001816 319 0.714
response to molecule of bacterial origin GO:0002237 143 0.628
regulation of cytokine production GO:0001817 266 0.574
placenta blood vessel development GO:0060674 31 0.514
Mouse
leukocyte differentiation GO:0002521 342 0.511
Mouse
positive regulation of t helper 1 cell differentiation GO:0045627 4 0.507
positive regulation of transforming growth factor beta2 production GO:0032915 2 0.505
negative regulation of transcription from rna polymerase ii promoter in response to stress GO:0097201 1 0.483
response to lipopolysaccharide GO:0032496 128 0.470
regulation of transferase activity GO:0051338 263 0.467
Fly
regulation of transcription from rna polymerase ii promoter in response to stress GO:0043618 8 0.424
positive regulation of nuclear transcribed mrna poly a tail shortening GO:0060213 4 0.424
negative regulation of cellular protein metabolic process GO:0032269 247 0.421
positive regulation of fibroblast proliferation GO:0048146 20 0.408
Mouse
positive regulation of apoptotic process GO:0043065 217 0.398
placenta development GO:0001890 140 0.396
Mouse
negative regulation of multi organism process GO:0043901 68 0.381
conditioned taste aversion GO:0001661 4 0.369
positive regulation of cell death GO:0010942 224 0.358
mitochondrion organization GO:0007005 134 0.346
regulation of cyclin dependent protein serine threonine kinase activity GO:0000079 16 0.345
Fly
interspecies interaction between organisms GO:0044419 83 0.338
transforming growth factor beta2 production GO:0032906 2 0.325
striated muscle tissue development GO:0014706 293 0.324
skeletal muscle organ development GO:0060538 163 0.319
positive regulation of mrna 3 end processing GO:0031442 5 0.304
regulation of protein kinase activity GO:0045859 232 0.296
Fly
response to metal ion GO:0010038 47 0.276
Mouse
regulation of neuron apoptotic process GO:0043523 122 0.275
t cell differentiation GO:0030217 174 0.274
cell type specific apoptotic process GO:0097285 268 0.273
positive regulation of neutrophil mediated killing of symbiont cell GO:0070961 1 0.273
jnk cascade GO:0007254 72 0.270
positive regulation of cytokine production GO:0001819 174 0.266
ras protein signal transduction GO:0007265 77 0.265
positive regulation of neuron apoptotic process GO:0043525 25 0.259
immune effector process GO:0002252 321 0.258
regulation of defense response GO:0031347 233 0.253
regulation of antimicrobial humoral response GO:0002759 3 0.253
response to radiation GO:0009314 165 0.253
regulation of brown fat cell differentiation GO:0090335 5 0.251
brain segmentation GO:0035284 3 0.250
blood vessel morphogenesis GO:0048514 285 0.248
response to endoplasmic reticulum stress GO:0034976 53 0.241
negative regulation of protein metabolic process GO:0051248 282 0.241
microglial cell activation GO:0001774 3 0.241
stress activated protein kinase signaling cascade GO:0031098 81 0.241
regulation of cell cycle GO:0051726 281 0.238
Fly
positive regulation of programmed cell death GO:0043068 218 0.234
negative regulation of response to wounding GO:1903035 77 0.229
fat cell differentiation GO:0045444 160 0.227
Mouse
nucleobase containing small molecule metabolic process GO:0055086 352 0.223
negative regulation of phosphorylation GO:0042326 166 0.221
regulation of cellular amino acid metabolic process GO:0006521 5 0.220
regulation of kinase activity GO:0043549 249 0.218
Fly
positive regulation of protein modification process GO:0031401 299 0.212
Mouse
osteoclast differentiation GO:0030316 62 0.203
Mouse
cellular response to gamma radiation GO:0071480 4 0.202
response to organic cyclic compound GO:0014070 198 0.201
regulation of neutrophil mediated killing of gram negative bacterium GO:0070951 1 0.200
myeloid cell differentiation GO:0030099 233 0.200
Mouse
cation transport GO:0006812 399 0.199
regulation of leukocyte differentiation GO:1902105 159 0.196
Mouse
cellular response to inorganic substance GO:0071241 37 0.193
Mouse
cellular ketone metabolic process GO:0042180 84 0.190
t cell differentiation in thymus GO:0033077 77 0.185
covalent chromatin modification GO:0016569 163 0.181
Mouse
symbiosis encompassing mutualism through parasitism GO:0044403 83 0.180
regulation of nucleotide metabolic process GO:0006140 169 0.175
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.172
positive regulation of leukocyte differentiation GO:1902107 86 0.172
Mouse
regulation of multi organism process GO:0043900 111 0.171
regulation of inflammatory response GO:0050727 147 0.171
positive regulation of rhodopsin gene expression GO:0045872 2 0.169
muscle tissue development GO:0060537 308 0.169
wound healing GO:0042060 157 0.167
Fly
chromatin organization GO:0006325 206 0.165
Mouse
nucleoside phosphate metabolic process GO:0006753 338 0.161
fibroblast proliferation GO:0048144 35 0.160
Mouse
regulation of fibroblast proliferation GO:0048145 34 0.159
Mouse
small gtpase mediated signal transduction GO:0007264 97 0.158
negative regulation of protein modification process GO:0031400 163 0.158
heterocycle catabolic process GO:0046700 280 0.157
regulation of cellular catabolic process GO:0031329 242 0.154
negative regulation of protein kinase activity by regulation of protein phosphorylation GO:0044387 2 0.153
positive regulation of nuclear transcribed mrna catabolic process deadenylation dependent decay GO:1900153 5 0.153
neutrophil mediated killing of gram negative bacterium GO:0070945 4 0.152
response to transforming growth factor beta GO:0071559 88 0.152
positive regulation of myeloid leukocyte differentiation GO:0002763 26 0.149
Mouse
purine ribonucleotide metabolic process GO:0009150 290 0.149
regeneration GO:0031099 38 0.148
Fly
myeloid leukocyte activation GO:0002274 83 0.148
purine nucleotide metabolic process GO:0006163 302 0.147
positive regulation of ras gtpase activity GO:0032320 65 0.147
glycosyl compound metabolic process GO:1901657 246 0.145
interaction with symbiont GO:0051702 14 0.144
cellular response to biotic stimulus GO:0071216 92 0.143
negative regulation of molecular function GO:0044092 258 0.143
negative regulation of viral transcription GO:0032897 3 0.142
negative regulation of phosphorus metabolic process GO:0010563 184 0.142
apoptotic mitochondrial changes GO:0008637 48 0.141
regulation of myeloid leukocyte differentiation GO:0002761 58 0.140
Mouse
positive regulation of neutrophil mediated cytotoxicity GO:0070960 1 0.140
regulation of response to biotic stimulus GO:0002831 38 0.138
cytoplasmic transport GO:0016482 234 0.137
regulation of osteoclast differentiation GO:0045670 36 0.134
Mouse
rhythmic process GO:0048511 174 0.133
Fly
endocytosis GO:0006897 168 0.132
release of cytochrome c from mitochondria GO:0001836 23 0.132
mapk cascade GO:0000165 281 0.132
negative regulation of phosphate metabolic process GO:0045936 184 0.131
thymocyte migration GO:0072679 2 0.130
vitellogenesis GO:0007296 2 0.130
Mouse
t cell activation GO:0042110 289 0.128
circadian rhythm GO:0007623 114 0.126
Fly
cd4 positive alpha beta t cell cytokine production GO:0035743 4 0.126
regulation of plasminogen activation GO:0010755 4 0.124
regulation of transforming growth factor beta2 production GO:0032909 2 0.124
regulation of organelle organization GO:0033043 289 0.123
Mouse
positive regulation of monocyte chemotaxis GO:0090026 2 0.123
ribose phosphate metabolic process GO:0019693 291 0.123
skeletal muscle cell differentiation GO:0035914 66 0.122
cation homeostasis GO:0055080 212 0.122
compound eye development GO:0048749 1 0.122
Fly
viral gene expression GO:0019080 3 0.122
cellular response to transforming growth factor beta stimulus GO:0071560 88 0.121
embryonic process involved in female pregnancy GO:0060136 7 0.121
aromatic compound catabolic process GO:0019439 286 0.121
regulation of neuron death GO:1901214 134 0.120
regulation of neutrophil mediated killing of symbiont cell GO:0070949 2 0.120
positive regulation of organelle organization GO:0010638 128 0.119
Mouse
histone deacetylation GO:0016575 26 0.119
Mouse
positive regulation of rho gtpase activity GO:0032321 41 0.118
regulation of protein autophosphorylation GO:0031952 8 0.118
central nervous system segmentation GO:0035283 3 0.118
neuron apoptotic process GO:0051402 142 0.117
response to drug GO:0042493 75 0.116
Mouse
organic cyclic compound catabolic process GO:1901361 295 0.116
modification of morphology or physiology of other organism involved in symbiotic interaction GO:0051817 16 0.116
nucleoside metabolic process GO:0009116 246 0.115
interleukin 8 production GO:0032637 4 0.115
cellular nitrogen compound catabolic process GO:0044270 280 0.115
response to inorganic substance GO:0010035 96 0.114
Mouse
positive regulation of gtp catabolic process GO:0033126 85 0.114
neuron projection regeneration GO:0031102 14 0.114
Fly
positive regulation of reactive oxygen species metabolic process GO:2000379 11 0.114
positive regulation of epithelial cell proliferation GO:0050679 68 0.113
purine containing compound metabolic process GO:0072521 311 0.112
nucleotide metabolic process GO:0009117 332 0.111
negative regulation of fat cell differentiation GO:0045599 36 0.111
Mouse
regulation of response to wounding GO:1903034 189 0.111
regulation of membrane potential GO:0042391 192 0.110
phagocytosis GO:0006909 66 0.108
axon regeneration GO:0031103 12 0.107
Fly
regulation of angiogenesis GO:0045765 81 0.107
apoptotic signaling pathway GO:0097190 306 0.107
lymphocyte differentiation GO:0030098 242 0.107
monosaccharide biosynthetic process GO:0046364 44 0.107
cellular response to lipopolysaccharide GO:0071222 77 0.106
regulation of interleukin 8 production GO:0032677 3 0.106
response to mineralocorticoid GO:0051385 1 0.106
reactive oxygen species metabolic process GO:0072593 84 0.106
labyrinthine layer blood vessel development GO:0060716 21 0.106
regulation of chromatin modification GO:1903308 57 0.106
Mouse
mitotic cell cycle GO:0000278 195 0.106
Fly
positive regulation of cellular catabolic process GO:0031331 148 0.105
neuron death GO:0070997 154 0.105
striated muscle cell development GO:0055002 125 0.103
camera type eye development GO:0043010 266 0.103
positive regulation of histone modification GO:0031058 28 0.103
Mouse
regulation of protein deacetylation GO:0090311 17 0.103
Mouse
negative regulation of neuron death GO:1901215 98 0.102
learning GO:0007612 98 0.102
leukocyte homeostasis GO:0001776 79 0.102
regulation of leukocyte apoptotic process GO:2000106 56 0.101
myeloid leukocyte differentiation GO:0002573 119 0.101
Mouse
embryonic placenta development GO:0001892 98 0.101
regulation of mapk cascade GO:0043408 248 0.100
rhombomere 5 development GO:0021571 4 0.099
regulation of gtp catabolic process GO:0033124 113 0.097
forebrain development GO:0030900 302 0.097
glycosyl compound catabolic process GO:1901658 206 0.096
macromolecule deacylation GO:0098732 37 0.095
Mouse
negative regulation of metanephric glomerular mesangial cell proliferation GO:0072302 1 0.093
purine nucleotide catabolic process GO:0006195 211 0.092
labyrinthine layer development GO:0060711 49 0.092
developmental maturation GO:0021700 193 0.092
regulation of nucleoside metabolic process GO:0009118 130 0.091
positive regulation of protein kinase activity GO:0045860 144 0.091
activation of mapkkk activity GO:0000185 1 0.091
regulation of ossification GO:0030278 112 0.091
regulation of rho gtpase activity GO:0032319 58 0.090
regulation of ras gtpase activity GO:0032318 88 0.090
positive regulation of nucleotide catabolic process GO:0030813 88 0.090
positive regulation of neuron death GO:1901216 28 0.090
negative regulation of respiratory burst involved in inflammatory response GO:0060266 1 0.089
regulation of protein serine threonine kinase activity GO:0071900 157 0.088
Fly
chromatin modification GO:0016568 187 0.086
Mouse
regulation of cellular response to stress GO:0080135 159 0.085
guanosine containing compound catabolic process GO:1901069 144 0.085
positive regulation of nucleoside metabolic process GO:0045979 91 0.085
glucose metabolic process GO:0006006 92 0.085
positive regulation of nucleotide metabolic process GO:0045981 114 0.083
positive regulation of protein phosphorylation GO:0001934 242 0.083
gland development GO:0048732 330 0.083
mitotic cell cycle process GO:1903047 159 0.083
Fly
dna metabolic process GO:0006259 303 0.083
cellular response to follicle stimulating hormone stimulus GO:0071372 1 0.083
modification of morphology or physiology of other organism GO:0035821 18 0.082
response to oxidative stress GO:0006979 123 0.082
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.082
guanosine containing compound metabolic process GO:1901068 144 0.081
regulation of hydrolase activity GO:0051336 246 0.081
response to calcium ion GO:0051592 20 0.081
Mouse
regulation of reactive oxygen species metabolic process GO:2000377 40 0.081
response to organonitrogen compound GO:0010243 246 0.081
cellular response to growth factor stimulus GO:0071363 197 0.081
regulation of respiratory burst involved in inflammatory response GO:0060264 2 0.081
regulation of chromosome organization GO:0033044 83 0.080
Mouse
nucleoside triphosphate catabolic process GO:0009143 205 0.080
response to extracellular stimulus GO:0009991 127 0.079
Mouse
regulation of ovulation GO:0060278 3 0.079
regulation of dna templated transcription in response to stress GO:0043620 9 0.079
regulation of chromatin organization GO:1902275 57 0.079
Mouse
purine containing compound catabolic process GO:0072523 213 0.078
histone modification GO:0016570 159 0.078
Mouse
regulation of histone modification GO:0031056 56 0.078
Mouse
modification by host of symbiont morphology or physiology GO:0051851 12 0.078
positive regulation of chromatin modification GO:1903310 28 0.078
Mouse
cellular response to external stimulus GO:0071496 88 0.077
Mouse
regulation of rho protein signal transduction GO:0035023 71 0.077
positive regulation of hematopoietic stem cell proliferation GO:1902035 2 0.077
amine metabolic process GO:0009308 45 0.077
adaptive immune response GO:0002250 155 0.076
positive regulation of blood circulation GO:1903524 22 0.076
cellular response to oxidative stress GO:0034599 76 0.075
cellular response to metal ion GO:0071248 31 0.074
Mouse
response to camp GO:0051591 14 0.074
positive regulation of osteoclast differentiation GO:0045672 15 0.073
Mouse
inflammatory response GO:0006954 244 0.073
ribonucleoside triphosphate catabolic process GO:0009203 199 0.073
ceramide biosynthetic process GO:0046513 20 0.072
heart contraction GO:0060047 93 0.072
germ cell development GO:0007281 185 0.071
Fly
negative regulation of inflammatory response GO:0050728 61 0.071
synapse organization GO:0050808 125 0.071
Fly
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.071
decidualization GO:0046697 10 0.070
membrane lipid biosynthetic process GO:0046467 32 0.070
rho protein signal transduction GO:0007266 32 0.070
viral process GO:0016032 41 0.070
positive regulation of leukocyte mediated cytotoxicity GO:0001912 31 0.070
circulatory system process GO:0003013 197 0.070
regulation of lymphocyte activation GO:0051249 240 0.069
negative regulation of ovulation GO:0060280 1 0.068
cellular response to molecule of bacterial origin GO:0071219 83 0.068
macrophage activation GO:0042116 27 0.068
cellular response to calcium ion GO:0071277 14 0.068
Mouse
general adaptation syndrome GO:0051866 2 0.067
muscle cell development GO:0055001 133 0.067
cellular response to dna damage stimulus GO:0006974 207 0.067
purine nucleoside catabolic process GO:0006152 205 0.067
humoral immune response GO:0006959 57 0.067
Fly
mrna 3 end processing GO:0031124 16 0.066
central nervous system neuron development GO:0021954 67 0.066
response to reactive oxygen species GO:0000302 56 0.066
cellular response to organic cyclic compound GO:0071407 87 0.066
connective tissue development GO:0061448 179 0.066
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.065
t helper 2 cell cytokine production GO:0035745 4 0.065
regulation of rhodopsin gene expression GO:0007468 3 0.065
metanephric glomerular mesangium development GO:0072223 3 0.065
regulation of eosinophil migration GO:2000416 2 0.065
regulation of ras protein signal transduction GO:0046578 114 0.065
purine ribonucleoside catabolic process GO:0046130 205 0.064
regulation of ion transport GO:0043269 215 0.064
epithelial cell proliferation GO:0050673 174 0.064
blood circulation GO:0008015 195 0.064
positive regulation of purine nucleotide catabolic process GO:0033123 88 0.063
negative regulation of protein phosphorylation GO:0001933 126 0.063
regulation of adaptive immune response GO:0002819 90 0.063
cellular response to lipid GO:0071396 145 0.063
transmembrane transport GO:0055085 412 0.063
negative regulation of defense response GO:0031348 77 0.062
ribonucleoside catabolic process GO:0042454 206 0.062
ribonucleoside metabolic process GO:0009119 245 0.062
circadian behavior GO:0048512 13 0.062
Fly
organophosphate catabolic process GO:0046434 232 0.062
regulation of defense response to fungus GO:1900150 1 0.061
ribonucleoside triphosphate metabolic process GO:0009199 220 0.061
cell cycle g2 m phase transition GO:0044839 20 0.060
Fly
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.060
fibrinolysis GO:0042730 3 0.059
regulation of purine nucleotide catabolic process GO:0033121 122 0.059
intracellular protein transport GO:0006886 204 0.059
regulation of protein maturation GO:1903317 96 0.059
glial cell differentiation GO:0010001 131 0.059
transforming growth factor beta receptor signaling pathway GO:0007179 71 0.058
viral life cycle GO:0019058 36 0.058
purine ribonucleotide catabolic process GO:0009154 208 0.057
macromolecule methylation GO:0043414 120 0.057
axonogenesis GO:0007409 274 0.057
Fly
adrenal cortex development GO:0035801 2 0.057
response to nutrient levels GO:0031667 109 0.057
regulation of neutrophil mediated cytotoxicity GO:0070948 2 0.057
regulation of fibrinolysis GO:0051917 1 0.057
positive regulation of kinase activity GO:0033674 155 0.056
chemotaxis GO:0006935 247 0.056
negative regulation of immune system process GO:0002683 209 0.056
purine nucleoside metabolic process GO:0042278 241 0.055
ribonucleotide metabolic process GO:0009259 291 0.054
tumor necrosis factor production GO:0032640 50 0.054
regulation of myeloid cell differentiation GO:0045637 96 0.054
Mouse
cd4 positive alpha beta t cell differentiation GO:0043367 41 0.053
gtp metabolic process GO:0046039 144 0.053
blastocyst development GO:0001824 80 0.053
muscle cell differentiation GO:0042692 261 0.053
skeletal system development GO:0001501 356 0.053
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.052
fertilization GO:0009566 127 0.052
regulation of viral transcription GO:0046782 3 0.052
cell growth GO:0016049 130 0.052
Fly
purine ribonucleoside metabolic process GO:0046128 241 0.052
regulation of fat cell differentiation GO:0045598 81 0.052
Mouse
positive regulation of eosinophil migration GO:2000418 2 0.052
regulation of respiratory burst GO:0060263 2 0.052
negative regulation of viral process GO:0048525 23 0.052
regulation of mitotic cell cycle phase transition GO:1901990 73 0.052
negative regulation of jun kinase activity GO:0043508 9 0.051
response to steroid hormone GO:0048545 56 0.051
protein localization to organelle GO:0033365 185 0.051
learning or memory GO:0007611 148 0.051
homeostasis of number of cells GO:0048872 210 0.051
regulation of heart contraction GO:0008016 77 0.051
synapse assembly GO:0007416 56 0.050
Fly
sensory system development GO:0048880 3 0.050
regulation of protein localization GO:0032880 231 0.050
cognition GO:0050890 149 0.050
ossification GO:0001503 216 0.049
adipose tissue development GO:0060612 25 0.049
male gamete generation GO:0048232 285 0.049
regulation of cell motility GO:2000145 236 0.049
ribonucleotide catabolic process GO:0009261 208 0.048
gtp catabolic process GO:0006184 143 0.048
membrane depolarization GO:0051899 64 0.048
negative regulation of protein serine threonine kinase activity GO:0071901 49 0.048
negative regulation of intracellular signal transduction GO:1902532 167 0.048
regulation of hematopoietic stem cell proliferation GO:1902033 3 0.048
regulation of thymocyte migration GO:2000410 2 0.048
positive regulation of b cell chemotaxis GO:2000538 2 0.048
positive regulation of chromosome organization GO:2001252 33 0.048
Mouse
cell adhesion GO:0007155 329 0.047
establishment of protein localization to organelle GO:0072594 118 0.047
regulation of cell activation GO:0050865 289 0.046
gene silencing by mirna GO:0035195 10 0.046
positive regulation of myeloid cell differentiation GO:0045639 43 0.046
Mouse
carbohydrate derivative catabolic process GO:1901136 231 0.046
regulation of neutrophil mediated killing of fungus GO:0070953 1 0.046
positive regulation of hydrolase activity GO:0051345 148 0.046
protein autophosphorylation GO:0046777 61 0.046
cellular response to cytokine stimulus GO:0071345 189 0.046
cellular response to extracellular stimulus GO:0031668 81 0.046
Mouse
nucleotide catabolic process GO:0009166 217 0.045
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 52 0.045
regulation of apoptotic signaling pathway GO:2001233 197 0.045
calcium ion transport GO:0006816 159 0.045
positive regulation of sphingolipid biosynthetic process GO:0090154 1 0.045
angiogenesis GO:0001525 201 0.045
regulation of t cell activation GO:0050863 170 0.045
maternal process involved in female pregnancy GO:0060135 32 0.045
rhombomere 5 formation GO:0021666 1 0.045
positive regulation of transcription from rna polymerase ii promoter in response to stress GO:0036003 3 0.045
regulation of myotube differentiation GO:0010830 62 0.044
maternal placenta development GO:0001893 20 0.044
nuclear transcribed mrna poly a tail shortening GO:0000289 7 0.044
organonitrogen compound catabolic process GO:1901565 264 0.044
skeletal muscle fiber development GO:0048741 58 0.043
response to growth factor GO:0070848 198 0.043
negative regulation of neuron apoptotic process GO:0043524 92 0.043
gliogenesis GO:0042063 141 0.043
defense response to bacterium GO:0042742 119 0.043
negative regulation of proteolysis GO:0045861 74 0.043
nucleoside triphosphate metabolic process GO:0009141 230 0.042
negative regulation of cell cycle GO:0045786 123 0.042
regulation of defense response to bacterium GO:1900424 3 0.042
cellular amine metabolic process GO:0044106 44 0.042
multicellular organismal homeostasis GO:0048871 164 0.042
protein modification by small protein conjugation GO:0032446 187 0.042
negative regulation of endopeptidase activity GO:0010951 44 0.041
negative regulation of cyclin dependent protein serine threonine kinase activity GO:0045736 9 0.041
purine nucleoside triphosphate metabolic process GO:0009144 226 0.041
regulation of map kinase activity GO:0043405 120 0.040
nucleoside phosphate catabolic process GO:1901292 222 0.040
nucleoside catabolic process GO:0009164 206 0.040
alpha beta t cell activation GO:0046631 91 0.040
arachidonic acid metabolite production involved in inflammatory response GO:0002538 2 0.039
developmental growth involved in morphogenesis GO:0060560 138 0.039
Fly
carbohydrate metabolic process GO:0005975 230 0.039
positive regulation of mitochondrial membrane permeability involved in apoptotic process GO:1902110 11 0.039
leukocyte activation involved in immune response GO:0002366 126 0.039
response to light stimulus GO:0009416 135 0.039
rna processing GO:0006396 105 0.038
positive regulation of osteoblast differentiation GO:0045669 34 0.038
viral transcription GO:0019083 3 0.038
response to corticosterone GO:0051412 1 0.038
regulation of cellular component biogenesis GO:0044087 181 0.038
positive regulation of gtpase activity GO:0043547 85 0.038
liver development GO:0001889 66 0.038
regulation of osteoblast differentiation GO:0045667 67 0.037
cellular divalent inorganic cation homeostasis GO:0072503 127 0.037
cellular amino acid metabolic process GO:0006520 103 0.037
heart morphogenesis GO:0003007 178 0.037
response to catecholamine GO:0071869 4 0.037
innate immune response GO:0045087 157 0.037
blastocyst formation GO:0001825 33 0.037
nuclear transcribed mrna catabolic process GO:0000956 16 0.036
alpha beta t cell differentiation involved in immune response GO:0002293 30 0.036
canonical wnt signaling pathway GO:0060070 130 0.036
smad protein signal transduction GO:0060395 21 0.036
response to starvation GO:0042594 65 0.036
negative regulation of innate immune response GO:0045824 17 0.036
response to purine containing compound GO:0014074 28 0.036
regulation of muscle tissue development GO:1901861 97 0.035
monosaccharide metabolic process GO:0005996 106 0.035
hexose metabolic process GO:0019318 98 0.035
cellular calcium ion homeostasis GO:0006874 119 0.035
positive regulation of syncytium formation by plasma membrane fusion GO:0060143 17 0.035
negative regulation of cellular component organization GO:0051129 194 0.035
regulation of stress activated mapk cascade GO:0032872 69 0.035
regulation of neuron projection development GO:0010975 169 0.034
negative regulation of protein autophosphorylation GO:0031953 2 0.034
rhombomere morphogenesis GO:0021593 2 0.034
stress activated mapk cascade GO:0051403 80 0.034
muscle cell proliferation GO:0033002 52 0.033
positive regulation of cell motility GO:2000147 116 0.033
neural tube development GO:0021915 160 0.033
positive regulation of cell killing GO:0031343 33 0.033
protein import into nucleus GO:0006606 95 0.033
regulation of killing of cells of other organism GO:0051709 4 0.033
response to organophosphorus GO:0046683 22 0.033
negative regulation of cellular amine metabolic process GO:0033239 1 0.033
protein deacetylation GO:0006476 32 0.033
Mouse
negative regulation of cell proliferation GO:0008285 296 0.033
metal ion homeostasis GO:0055065 189 0.033
divalent inorganic cation transport GO:0072511 178 0.033
extrinsic apoptotic signaling pathway GO:0097191 126 0.032
positive regulation of transcription from rna polymerase i promoter GO:0045943 3 0.032
g2 m transition of mitotic cell cycle GO:0000086 20 0.032
Fly
mrna processing GO:0006397 63 0.032
cell maturation GO:0048469 127 0.032
regulation of striated muscle cell differentiation GO:0051153 81 0.032
alpha beta t cell differentiation GO:0046632 69 0.032
regulation of skeletal muscle fiber development GO:0048742 36 0.032
regulation of ion transmembrane transport GO:0034765 119 0.031
negative regulation of metanephric glomerulus development GO:0072299 1 0.031
t cell activation involved in immune response GO:0002286 43 0.031
positive regulation of mapk cascade GO:0043410 170 0.031
regulation of alpha beta t cell differentiation GO:0046637 35 0.031
rna stabilization GO:0043489 9 0.031
positive regulation of defense response GO:0031349 124 0.031
adrenal cortex formation GO:0035802 2 0.031
regulation of system process GO:0044057 200 0.031
positive regulation of cell activation GO:0050867 158 0.031
female gamete generation GO:0007292 74 0.031
Mouse Fly
positive regulation of neutrophil mediated killing of fungus GO:0070965 1 0.031
organelle assembly GO:0070925 177 0.030
negative regulation of t helper 2 cell differentiation GO:0045629 4 0.030
regulation of monocyte chemotaxis GO:0090025 3 0.030
sperm motility GO:0030317 47 0.030
carbohydrate biosynthetic process GO:0016051 74 0.030
cellular ion homeostasis GO:0006873 165 0.030
protein ubiquitination GO:0016567 171 0.030
rna 3 end processing GO:0031123 20 0.030
nucleocytoplasmic transport GO:0006913 139 0.029
cellular chemical homeostasis GO:0055082 215 0.029
chondrocyte differentiation GO:0002062 72 0.029
negative regulation of muscle cell differentiation GO:0051148 33 0.029
cellular response to nutrient levels GO:0031669 64 0.029
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.029
glomerular mesangial cell proliferation GO:0072110 3 0.029
negative regulation of cell activation GO:0050866 111 0.029
skin development GO:0043588 220 0.029
positive regulation of t helper 2 cell cytokine production GO:2000553 3 0.029
regulation of cell migration involved in sprouting angiogenesis GO:0090049 4 0.029
response to hydrogen peroxide GO:0042542 32 0.029
macromolecule catabolic process GO:0009057 281 0.029
membrane organization GO:0061024 245 0.029
regulation of ceramide biosynthetic process GO:2000303 1 0.029
chorio allantoic fusion GO:0060710 8 0.029
myotube cell development GO:0014904 60 0.029

Atf3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.072
nervous system disease DOID:863 0 0.072
neuropathy DOID:870 0 0.072
neuromuscular disease DOID:440 0 0.059
cancer DOID:162 0 0.037
disease of cellular proliferation DOID:14566 0 0.037
organ system cancer DOID:0050686 0 0.034
charcot marie tooth disease DOID:10595 0 0.033