Mus musculus

0 known processes

Ldoc1

leucine zipper, down-regulated in cancer 1

(Aliases: Mar7,Mart7,Gm366)

Ldoc1 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
transmembrane transport GO:0055085 412 0.248
cellular amino acid metabolic process GO:0006520 103 0.091
regulation of cellular amino acid metabolic process GO:0006521 5 0.083
amine metabolic process GO:0009308 45 0.082
ion transmembrane transport GO:0034220 361 0.081
cellular ketone metabolic process GO:0042180 84 0.079
cation transmembrane transport GO:0098655 266 0.075
sensory organ morphogenesis GO:0090596 242 0.064
forebrain development GO:0030900 302 0.062
regulation of transmembrane transport GO:0034762 128 0.055
nucleobase containing small molecule metabolic process GO:0055086 352 0.055
embryonic organ morphogenesis GO:0048562 276 0.054
cellular amine metabolic process GO:0044106 44 0.052
regulation of cellular amine metabolic process GO:0033238 20 0.051
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.047
inorganic cation transmembrane transport GO:0098662 207 0.047
purine nucleotide metabolic process GO:0006163 302 0.046
g protein coupled receptor signaling pathway GO:0007186 243 0.045
urogenital system development GO:0001655 261 0.044
epithelial tube morphogenesis GO:0060562 303 0.043
negative regulation of cell proliferation GO:0008285 296 0.043
positive regulation of nervous system development GO:0051962 221 0.040
anion transport GO:0006820 177 0.040
organic anion transport GO:0015711 137 0.039
regulation of neuron differentiation GO:0045664 281 0.039
heart process GO:0003015 94 0.038
ribonucleotide metabolic process GO:0009259 291 0.038
organonitrogen compound biosynthetic process GO:1901566 192 0.038
macromolecule catabolic process GO:0009057 281 0.037
blood vessel morphogenesis GO:0048514 285 0.037
purine containing compound metabolic process GO:0072521 311 0.037
camera type eye development GO:0043010 266 0.036
spermatogenesis GO:0007283 284 0.036
cation transport GO:0006812 399 0.035
ribose phosphate metabolic process GO:0019693 291 0.035
inorganic ion transmembrane transport GO:0098660 234 0.035
stem cell differentiation GO:0048863 268 0.035
regulation of cellular ketone metabolic process GO:0010565 66 0.034
circulatory system process GO:0003013 197 0.034
positive regulation of cell development GO:0010720 237 0.034
carbohydrate derivative biosynthetic process GO:1901137 183 0.034
striated muscle tissue development GO:0014706 293 0.034
regulation of membrane potential GO:0042391 192 0.033
negative regulation of cellular amine metabolic process GO:0033239 1 0.033
blood circulation GO:0008015 195 0.033
axonogenesis GO:0007409 274 0.032
telencephalon development GO:0021537 186 0.032
peptidyl amino acid modification GO:0018193 336 0.032
purine ribonucleotide metabolic process GO:0009150 290 0.032
mesodermal cell migration GO:0008078 4 0.032
metal ion homeostasis GO:0055065 189 0.032
nucleotide metabolic process GO:0009117 332 0.031
gland development GO:0048732 330 0.031
neural precursor cell proliferation GO:0061351 121 0.031
negative regulation of phosphorus metabolic process GO:0010563 184 0.031
cellular macromolecule catabolic process GO:0044265 206 0.030
renal system development GO:0072001 225 0.030
regulation of system process GO:0044057 200 0.030
cation homeostasis GO:0055080 212 0.030
ras protein signal transduction GO:0007265 77 0.029
glycosyl compound metabolic process GO:1901657 246 0.029
regulation of cell migration GO:0030334 219 0.029
regulation of ion transmembrane transport GO:0034765 119 0.029
response to organonitrogen compound GO:0010243 246 0.029
skeletal system development GO:0001501 356 0.029
cognition GO:0050890 149 0.028
regulation of muscle tissue development GO:1901861 97 0.028
protein modification by small protein conjugation GO:0032446 187 0.028
male gamete generation GO:0048232 285 0.027
protein modification by small protein conjugation or removal GO:0070647 207 0.027
carbohydrate derivative catabolic process GO:1901136 231 0.027
wnt signaling pathway GO:0016055 188 0.027
positive regulation of neuron differentiation GO:0045666 141 0.027
regulation of organelle organization GO:0033043 289 0.027
microtubule based process GO:0007017 236 0.027
learning or memory GO:0007611 148 0.027
ameboidal type cell migration GO:0001667 128 0.026
organic cyclic compound catabolic process GO:1901361 295 0.026
regulation of hormone levels GO:0010817 211 0.026
regulation of nucleotide metabolic process GO:0006140 169 0.026
cellular response to hormone stimulus GO:0032870 150 0.026
regulation of mapk cascade GO:0043408 248 0.026
regulation of ion transport GO:0043269 215 0.025
myeloid leukocyte differentiation GO:0002573 119 0.025
ossification GO:0001503 216 0.025
stem cell development GO:0048864 219 0.025
skin development GO:0043588 220 0.025
heart contraction GO:0060047 93 0.025
cell adhesion GO:0007155 329 0.025
rhythmic process GO:0048511 174 0.025
nitrogen compound transport GO:0071705 271 0.024
heterocycle catabolic process GO:0046700 280 0.024
negative regulation of phosphate metabolic process GO:0045936 184 0.024
locomotory behavior GO:0007626 195 0.024
angiogenesis GO:0001525 201 0.024
regulation of transferase activity GO:0051338 263 0.024
carboxylic acid transport GO:0046942 100 0.024
response to molecule of bacterial origin GO:0002237 143 0.024
purine nucleotide catabolic process GO:0006195 211 0.023
developmental maturation GO:0021700 193 0.023
branching morphogenesis of an epithelial tube GO:0048754 159 0.023
positive regulation of nucleotide metabolic process GO:0045981 114 0.023
tube formation GO:0035148 140 0.023
regulation of cell motility GO:2000145 236 0.023
negative regulation of cell development GO:0010721 169 0.023
cellular lipid metabolic process GO:0044255 323 0.023
negative regulation of cellular component organization GO:0051129 194 0.023
carbohydrate metabolic process GO:0005975 230 0.022
heart morphogenesis GO:0003007 178 0.022
positive regulation of cellular amine metabolic process GO:0033240 5 0.022
response to organic cyclic compound GO:0014070 198 0.022
muscle cell differentiation GO:0042692 261 0.022
generation of precursor metabolites and energy GO:0006091 103 0.022
ear development GO:0043583 200 0.022
regulation of cell cycle GO:0051726 281 0.022
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.022
endomembrane system organization GO:0010256 147 0.022
fat cell differentiation GO:0045444 160 0.022
pallium development GO:0021543 120 0.021
small gtpase mediated signal transduction GO:0007264 97 0.021
mitochondrion organization GO:0007005 134 0.021
regulation of heart contraction GO:0008016 77 0.021
conditioned taste aversion GO:0001661 4 0.021
adenylate cyclase modulating g protein coupled receptor signaling pathway GO:0007188 54 0.021
cell maturation GO:0048469 127 0.021
positive regulation of protein modification process GO:0031401 299 0.021
organophosphate biosynthetic process GO:0090407 122 0.021
nucleoside phosphate metabolic process GO:0006753 338 0.021
muscle fiber development GO:0048747 76 0.021
regulation of synaptic plasticity GO:0048167 87 0.021
cell division GO:0051301 120 0.021
sodium ion transport GO:0006814 73 0.021
amino acid transport GO:0006865 61 0.021
cellular chemical homeostasis GO:0055082 215 0.021
regulation of cell activation GO:0050865 289 0.021
morphogenesis of a branching epithelium GO:0061138 193 0.021
homeostasis of number of cells GO:0048872 210 0.021
placenta development GO:0001890 140 0.021
muscle tissue development GO:0060537 308 0.021
central nervous system neuron differentiation GO:0021953 162 0.021
dna metabolic process GO:0006259 303 0.020
limbic system development GO:0021761 72 0.020
sensory perception GO:0007600 245 0.020
regulation of cellular catabolic process GO:0031329 242 0.020
appendage morphogenesis GO:0035107 149 0.020
negative regulation of nervous system development GO:0051961 156 0.020
synaptic transmission GO:0007268 329 0.020
cellular homeostasis GO:0019725 240 0.020
oxidation reduction process GO:0055114 342 0.020
regulation of purine nucleotide metabolic process GO:1900542 169 0.020
multicellular organism growth GO:0035264 161 0.020
stem cell maintenance GO:0019827 130 0.020
muscle cell development GO:0055001 133 0.020
regulation of apoptotic signaling pathway GO:2001233 197 0.020
transmission of nerve impulse GO:0019226 76 0.020
cellular component assembly involved in morphogenesis GO:0010927 139 0.020
purine ribonucleotide catabolic process GO:0009154 208 0.019
hexose metabolic process GO:0019318 98 0.019
epithelial cell migration GO:0010631 63 0.019
regulation of cytokine production GO:0001817 266 0.019
positive regulation of growth GO:0045927 104 0.019
multicellular organismal signaling GO:0035637 91 0.019
tissue remodeling GO:0048771 102 0.019
covalent chromatin modification GO:0016569 163 0.019
glucose homeostasis GO:0042593 128 0.019
positive regulation of mapk cascade GO:0043410 170 0.019
appendage development GO:0048736 166 0.019
positive regulation of cytokine production GO:0001819 174 0.019
microtubule cytoskeleton organization GO:0000226 157 0.018
response to peptide hormone GO:0043434 127 0.018
amide transport GO:0042886 138 0.018
organonitrogen compound catabolic process GO:1901565 264 0.018
regulation of hydrolase activity GO:0051336 246 0.018
sperm motility GO:0030317 47 0.018
epithelial tube formation GO:0072175 130 0.018
protein ubiquitination GO:0016567 171 0.018
neuromuscular process GO:0050905 99 0.018
regulation of blood pressure GO:0008217 93 0.018
macromolecule methylation GO:0043414 120 0.018
cardiac chamber development GO:0003205 108 0.017
acid secretion GO:0046717 33 0.017
leukocyte differentiation GO:0002521 342 0.017
regulation of protein kinase activity GO:0045859 232 0.017
development of primary sexual characteristics GO:0045137 143 0.017
developmental growth involved in morphogenesis GO:0060560 138 0.017
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger GO:0007187 55 0.017
methylation GO:0032259 134 0.017
nucleotide biosynthetic process GO:0009165 78 0.017
chromatin organization GO:0006325 206 0.017
regulation of heart rate GO:0002027 36 0.017
mesenchyme development GO:0060485 152 0.017
mitotic cell cycle GO:0000278 195 0.017
glucose metabolic process GO:0006006 92 0.017
lung development GO:0030324 164 0.017
regulation of protein catabolic process GO:0042176 108 0.017
mitochondrion distribution GO:0048311 4 0.017
cellular carbohydrate metabolic process GO:0044262 119 0.017
nucleoside phosphate biosynthetic process GO:1901293 79 0.017
chromatin modification GO:0016568 187 0.017
histone modification GO:0016570 159 0.017
semaphorin plexin signaling pathway involved in outflow tract morphogenesis GO:0071527 1 0.017
striated muscle cell development GO:0055002 125 0.017
cyclic nucleotide metabolic process GO:0009187 59 0.016
negative regulation of cell cycle GO:0045786 123 0.016
myeloid cell differentiation GO:0030099 233 0.016
ribonucleotide catabolic process GO:0009261 208 0.016
cellular protein catabolic process GO:0044257 155 0.016
monosaccharide metabolic process GO:0005996 106 0.016
hormone secretion GO:0046879 128 0.016
organelle localization GO:0051640 179 0.016
positive regulation of organelle organization GO:0010638 128 0.016
response to peptide GO:1901652 136 0.016
cellular response to growth factor stimulus GO:0071363 197 0.016
nuclear division GO:0000280 158 0.016
gliogenesis GO:0042063 141 0.016
reactive oxygen species metabolic process GO:0072593 84 0.016
female sex differentiation GO:0046660 84 0.016
cytokine production GO:0001816 319 0.016
ear morphogenesis GO:0042471 118 0.016
nucleoside metabolic process GO:0009116 246 0.015
neural tube development GO:0021915 160 0.015
purine nucleotide biosynthetic process GO:0006164 65 0.015
glial cell differentiation GO:0010001 131 0.015
regulation of mitotic cell cycle GO:0007346 126 0.015
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.015
camp biosynthetic process GO:0006171 31 0.015
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.015
positive regulation of cell motility GO:2000147 116 0.015
skeletal muscle organ development GO:0060538 163 0.015
purine nucleoside metabolic process GO:0042278 241 0.015
purine nucleoside triphosphate metabolic process GO:0009144 226 0.015
canonical wnt signaling pathway GO:0060070 130 0.015
cell growth GO:0016049 130 0.015
engulfment of apoptotic cell GO:0043652 3 0.015
carbohydrate homeostasis GO:0033500 128 0.015
response to light stimulus GO:0009416 135 0.015
organelle assembly GO:0070925 177 0.015
cellular nitrogen compound catabolic process GO:0044270 280 0.015
purine containing compound biosynthetic process GO:0072522 70 0.015
cardiac chamber morphogenesis GO:0003206 93 0.015
cellular response to dna damage stimulus GO:0006974 207 0.015
negative regulation of molecular function GO:0044092 258 0.015
nucleoside phosphate catabolic process GO:1901292 222 0.015
organelle fission GO:0048285 170 0.015
sensory system development GO:0048880 3 0.015
respiratory system development GO:0060541 190 0.014
ribonucleoside triphosphate metabolic process GO:0009199 220 0.014
regulation of protein localization GO:0032880 231 0.014
protein catabolic process GO:0030163 221 0.014
dephosphorylation GO:0016311 129 0.014
endocytosis GO:0006897 168 0.014
response to oxygen levels GO:0070482 62 0.014
ribose phosphate biosynthetic process GO:0046390 59 0.014
regulation of carbohydrate metabolic process GO:0006109 75 0.014
purine ribonucleotide biosynthetic process GO:0009152 59 0.014
retina morphogenesis in camera type eye GO:0060042 45 0.014
epithelium migration GO:0090132 63 0.014
proteoglycan biosynthetic process GO:0030166 20 0.014
negative regulation of synapse maturation GO:2000297 2 0.014
regulation of blood circulation GO:1903522 93 0.014
positive regulation of protein phosphorylation GO:0001934 242 0.014
negative regulation of protein metabolic process GO:0051248 282 0.014
response to radiation GO:0009314 165 0.014
protein kinase b signaling GO:0043491 74 0.014
purine nucleoside catabolic process GO:0006152 205 0.014
regulation of cell cycle process GO:0010564 160 0.014
action potential GO:0001508 78 0.014
detection of stimulus GO:0051606 84 0.014
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.014
spermatid development GO:0007286 108 0.014
lipid localization GO:0010876 126 0.014
membrane organization GO:0061024 245 0.014
protein processing GO:0016485 163 0.013
aromatic compound catabolic process GO:0019439 286 0.013
negative regulation of phosphorylation GO:0042326 166 0.013
regulation of stem cell proliferation GO:0072091 78 0.013
cilium morphogenesis GO:0060271 102 0.013
positive regulation of secretion GO:0051047 130 0.013
diencephalon development GO:0021536 63 0.013
regulation of cell projection organization GO:0031344 206 0.013
organophosphate catabolic process GO:0046434 232 0.013
erk1 and erk2 cascade GO:0070371 77 0.013
ribonucleoside metabolic process GO:0009119 245 0.013
rho protein signal transduction GO:0007266 32 0.013
cellular response to lipid GO:0071396 145 0.013
regulation of homeostatic process GO:0032844 182 0.013
organic acid transport GO:0015849 101 0.013
multicellular organismal response to stress GO:0033555 62 0.013
regulation of cellular carbohydrate metabolic process GO:0010675 75 0.013
myeloid leukocyte activation GO:0002274 83 0.013
purine containing compound catabolic process GO:0072523 213 0.013
regulation of cell adhesion GO:0030155 154 0.013
positive regulation of cell death GO:0010942 224 0.013
neuronal action potential GO:0019228 54 0.013
response to steroid hormone GO:0048545 56 0.013
morphogenesis of a branching structure GO:0001763 203 0.013
monocarboxylic acid metabolic process GO:0032787 191 0.013
nucleoside triphosphate catabolic process GO:0009143 205 0.013
regulation of cell division GO:0051302 76 0.013
cell type specific apoptotic process GO:0097285 268 0.013
single organismal cell cell adhesion GO:0016337 131 0.013
feeding behavior GO:0007631 62 0.013
epithelial cell development GO:0002064 159 0.013
mesoderm development GO:0007498 100 0.013
ribonucleoside catabolic process GO:0042454 206 0.013
lipid transport GO:0006869 98 0.013
inner ear morphogenesis GO:0042472 101 0.013
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.013
mapk cascade GO:0000165 281 0.013
negative regulation of cellular protein metabolic process GO:0032269 247 0.013
regulation of peptide hormone secretion GO:0090276 75 0.013
regionalization GO:0003002 337 0.013
retina development in camera type eye GO:0060041 119 0.013
protein secretion GO:0009306 111 0.012
regulation of ossification GO:0030278 112 0.012
negative regulation of organelle organization GO:0010639 90 0.012
multi multicellular organism process GO:0044706 109 0.012
neurotransmitter transport GO:0006836 76 0.012
neuron projection guidance GO:0097485 141 0.012
myotube differentiation GO:0014902 105 0.012
oocyte construction GO:0007308 2 0.012
ribonucleoside triphosphate catabolic process GO:0009203 199 0.012
regulation of ion transmembrane transporter activity GO:0032412 54 0.012
glycoprotein metabolic process GO:0009100 116 0.012
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.012
cellular response to peptide hormone stimulus GO:0071375 92 0.012
maintenance of location GO:0051235 89 0.012
protein localization to membrane GO:0072657 108 0.012
meiotic cell cycle GO:0051321 122 0.012
anatomical structure maturation GO:0071695 49 0.012
metencephalon development GO:0022037 89 0.012
cellular ion homeostasis GO:0006873 165 0.012
regulation of establishment of protein localization GO:0070201 181 0.012
lipid homeostasis GO:0055088 63 0.012
organic hydroxy compound metabolic process GO:1901615 203 0.012
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.012
digestive system development GO:0055123 200 0.012
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.012
response to nutrient levels GO:0031667 109 0.012
regulation of transporter activity GO:0032409 57 0.012
extracellular structure organization GO:0043062 148 0.012
purine ribonucleoside metabolic process GO:0046128 241 0.012
multicellular organismal homeostasis GO:0048871 164 0.012
cellular protein complex assembly GO:0043623 116 0.012
morphogenesis of embryonic epithelium GO:0016331 159 0.012
nucleotide catabolic process GO:0009166 217 0.012
posttranscriptional regulation of gene expression GO:0010608 155 0.012
sulfur compound biosynthetic process GO:0044272 37 0.012
neuromuscular process controlling balance GO:0050885 59 0.012
response to extracellular stimulus GO:0009991 127 0.012
peripheral nervous system development GO:0007422 53 0.012
modification dependent protein catabolic process GO:0019941 133 0.012
ovulation cycle GO:0042698 59 0.012
associative learning GO:0008306 61 0.012
regulation of epithelial cell migration GO:0010632 35 0.012
divalent metal ion transport GO:0070838 172 0.012
digestion GO:0007586 40 0.012
bmp signaling pathway GO:0030509 93 0.012
kidney development GO:0001822 213 0.012
regulation of angiogenesis GO:0045765 81 0.012
sulfur compound metabolic process GO:0006790 100 0.012
cholesterol homeostasis GO:0042632 44 0.012
developmental cell growth GO:0048588 84 0.011
glycosyl compound catabolic process GO:1901658 206 0.011
chondrocyte differentiation GO:0002062 72 0.011
protein maturation GO:0051604 176 0.011
divalent inorganic cation transport GO:0072511 178 0.011
hormone metabolic process GO:0042445 86 0.011
female gonad development GO:0008585 71 0.011
memory GO:0007613 58 0.011
positive regulation of hydrolase activity GO:0051345 148 0.011
regulation of secretion GO:0051046 274 0.011
regulation of ras gtpase activity GO:0032318 88 0.011
positive regulation of cell projection organization GO:0031346 95 0.011
negative regulation of intracellular signal transduction GO:1902532 167 0.011
neural tube formation GO:0001841 108 0.011
purine nucleoside triphosphate catabolic process GO:0009146 203 0.011
tissue migration GO:0090130 68 0.011
hindbrain development GO:0030902 128 0.011
peptidyl tyrosine phosphorylation GO:0018108 143 0.011
compound eye development GO:0048749 1 0.011
small molecule biosynthetic process GO:0044283 132 0.011
germ cell development GO:0007281 185 0.011
learning GO:0007612 98 0.011
fertilization GO:0009566 127 0.011
ribonucleotide biosynthetic process GO:0009260 59 0.011
regulation of nucleoside metabolic process GO:0009118 130 0.011
regulation of neuron death GO:1901214 134 0.011
ubiquitin dependent protein catabolic process GO:0006511 129 0.011
mitotic cell cycle process GO:1903047 159 0.011
multi organism behavior GO:0051705 62 0.011
peptide secretion GO:0002790 114 0.011
positive regulation of programmed cell death GO:0043068 218 0.011
amino acid transmembrane transport GO:0003333 37 0.011
cardiocyte differentiation GO:0035051 87 0.011
cyclic nucleotide biosynthetic process GO:0009190 44 0.011
cellular metal ion homeostasis GO:0006875 151 0.011
visual learning GO:0008542 44 0.011
embryonic placenta development GO:0001892 98 0.011
hippocampus development GO:0021766 52 0.011
tube closure GO:0060606 91 0.011
gonad development GO:0008406 141 0.011
lateral line system development GO:0048925 1 0.010
neuron neuron synaptic transmission GO:0007270 69 0.010
purine ribonucleoside catabolic process GO:0046130 205 0.010
endothelial cell migration GO:0043542 44 0.010
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.010
extracellular matrix organization GO:0030198 147 0.010
negative regulation of endothelial cell migration GO:0010596 4 0.010
skeletal system morphogenesis GO:0048705 203 0.010
modification dependent macromolecule catabolic process GO:0043632 133 0.010
muscle system process GO:0003012 141 0.010
cellular calcium ion homeostasis GO:0006874 119 0.010
calcium ion transmembrane transport GO:0070588 85 0.010
regulation of proteolysis GO:0030162 164 0.010
cellular potassium ion transport GO:0071804 43 0.010
positive regulation of stem cell proliferation GO:2000648 59 0.010
neuron migration GO:0001764 122 0.010
energy derivation by oxidation of organic compounds GO:0015980 77 0.010
cyclic purine nucleotide metabolic process GO:0052652 43 0.010
divalent inorganic cation homeostasis GO:0072507 138 0.010
response to insulin GO:0032868 100 0.010
intracellular receptor signaling pathway GO:0030522 74 0.010
positive regulation of apoptotic process GO:0043065 217 0.010
meiotic nuclear division GO:0007126 115 0.010
synapse organization GO:0050808 125 0.010
protein autophosphorylation GO:0046777 61 0.010
regulation of bmp signaling pathway GO:0030510 60 0.010
nucleoside catabolic process GO:0009164 206 0.010
spinal cord development GO:0021510 81 0.010
negative regulation of mitotic cell cycle GO:0045930 58 0.010

Ldoc1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.013
disease of cellular proliferation DOID:14566 0 0.013
disease of anatomical entity DOID:7 0 0.011
cardiovascular system disease DOID:1287 0 0.011