Mus musculus

234 known processes

Atp8a2

ATPase, aminophospholipid transporter-like, class I, type 8A, member 2

(Aliases: AI415030,Atpc1b,Ib)

Atp8a2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of cellular amino acid metabolic process GO:0006521 5 0.318
cellular amine metabolic process GO:0044106 44 0.259
transmembrane transport GO:0055085 412 0.192
nucleoside phosphate metabolic process GO:0006753 338 0.179
regulation of cellular ketone metabolic process GO:0010565 66 0.179
cation transport GO:0006812 399 0.176
cation transmembrane transport GO:0098655 266 0.169
regulation of cellular amine metabolic process GO:0033238 20 0.159
amine metabolic process GO:0009308 45 0.157
synaptic transmission GO:0007268 329 0.153
divalent inorganic cation transport GO:0072511 178 0.130
divalent inorganic cation homeostasis GO:0072507 138 0.122
cellular chemical homeostasis GO:0055082 215 0.110
detection of abiotic stimulus GO:0009582 60 0.102
inorganic cation transmembrane transport GO:0098662 207 0.097
cellular ketone metabolic process GO:0042180 84 0.091
ribonucleotide metabolic process GO:0009259 291 0.086
cellular ion homeostasis GO:0006873 165 0.078
calcium ion transport GO:0006816 159 0.073
detection of external stimulus GO:0009581 61 0.069
ion transmembrane transport GO:0034220 361 0.069
calcium ion homeostasis GO:0055074 127 0.066
apoptotic signaling pathway GO:0097190 306 0.065
cation homeostasis GO:0055080 212 0.064
response to organonitrogen compound GO:0010243 246 0.064
nucleobase containing small molecule metabolic process GO:0055086 352 0.063
cellular metal ion homeostasis GO:0006875 151 0.062
gland development GO:0048732 330 0.059
ribose phosphate metabolic process GO:0019693 291 0.059
protein localization to organelle GO:0033365 185 0.057
sodium ion transmembrane transport GO:0035725 49 0.057
g protein coupled receptor signaling pathway GO:0007186 243 0.057
sensory perception GO:0007600 245 0.056
regulation of cellular component biogenesis GO:0044087 181 0.056
cellular divalent inorganic cation homeostasis GO:0072503 127 0.054
oxidation reduction process GO:0055114 342 0.054
cellular amino acid metabolic process GO:0006520 103 0.054
detection of light stimulus GO:0009583 25 0.052
membrane organization GO:0061024 245 0.052
dendrite development GO:0016358 115 0.052
negative regulation of cellular component organization GO:0051129 194 0.051
organonitrogen compound biosynthetic process GO:1901566 192 0.050
sensory organ morphogenesis GO:0090596 242 0.049
calcium ion transmembrane transport GO:0070588 85 0.049
response to radiation GO:0009314 165 0.049
inorganic ion transmembrane transport GO:0098660 234 0.049
spermatid differentiation GO:0048515 115 0.047
cyclic nucleotide metabolic process GO:0009187 59 0.047
peptidyl amino acid modification GO:0018193 336 0.047
actin cytoskeleton organization GO:0030036 220 0.047
divalent metal ion transport GO:0070838 172 0.046
blood vessel morphogenesis GO:0048514 285 0.045
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.045
rhodopsin mediated signaling pathway GO:0016056 4 0.045
metal ion homeostasis GO:0055065 189 0.045
maintenance of location GO:0051235 89 0.044
negative regulation of cellular protein metabolic process GO:0032269 247 0.043
cytoplasmic transport GO:0016482 234 0.041
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.041
axonogenesis GO:0007409 274 0.041
sequestering of metal ion GO:0051238 19 0.041
heterocycle catabolic process GO:0046700 280 0.040
lateral inhibition GO:0046331 1 0.040
regulation of organelle organization GO:0033043 289 0.040
spermatid development GO:0007286 108 0.040
positive regulation of cellular amine metabolic process GO:0033240 5 0.039
cellular calcium ion homeostasis GO:0006874 119 0.039
protein targeting GO:0006605 143 0.038
regulation of ion transport GO:0043269 215 0.038
positive regulation of protein modification process GO:0031401 299 0.038
cognition GO:0050890 149 0.038
Mouse
peptidyl tyrosine phosphorylation GO:0018108 143 0.038
microtubule based process GO:0007017 236 0.037
response to growth factor GO:0070848 198 0.037
negative regulation of cellular amine metabolic process GO:0033239 1 0.035
regulation of cellular component size GO:0032535 121 0.035
myeloid leukocyte differentiation GO:0002573 119 0.035
response to organic cyclic compound GO:0014070 198 0.035
skin development GO:0043588 220 0.034
positive regulation of protein phosphorylation GO:0001934 242 0.034
cell type specific apoptotic process GO:0097285 268 0.033
regulation of metal ion transport GO:0010959 106 0.033
cell adhesion GO:0007155 329 0.033
purine ribonucleotide metabolic process GO:0009150 290 0.032
synapse organization GO:0050808 125 0.032
cellular response to growth factor stimulus GO:0071363 197 0.031
stem cell differentiation GO:0048863 268 0.031
nitrogen compound transport GO:0071705 271 0.030
response to light stimulus GO:0009416 135 0.030
renal system development GO:0072001 225 0.030
sequestering of calcium ion GO:0051208 18 0.029
regulation of feeding behavior GO:0060259 3 0.029
detection of stimulus GO:0051606 84 0.029
macromolecule catabolic process GO:0009057 281 0.029
extrinsic apoptotic signaling pathway GO:0097191 126 0.029
regulation of anatomical structure size GO:0090066 178 0.029
regulation of cytoskeleton organization GO:0051493 122 0.028
ameboidal type cell migration GO:0001667 128 0.028
protein polymerization GO:0051258 57 0.028
regulation of voltage gated calcium channel activity GO:1901385 4 0.027
learning or memory GO:0007611 148 0.027
Mouse
negative regulation of protein metabolic process GO:0051248 282 0.027
muscle tissue development GO:0060537 308 0.027
aromatic compound catabolic process GO:0019439 286 0.026
carbohydrate transport GO:0008643 62 0.026
locomotory behavior GO:0007626 195 0.026
organic hydroxy compound metabolic process GO:1901615 203 0.026
Mouse
negative regulation of protein phosphorylation GO:0001933 126 0.025
stem cell development GO:0048864 219 0.025
carboxylic acid transport GO:0046942 100 0.025
blood circulation GO:0008015 195 0.025
cellular lipid metabolic process GO:0044255 323 0.025
reactive oxygen species metabolic process GO:0072593 84 0.025
multicellular organism growth GO:0035264 161 0.025
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.025
camera type eye development GO:0043010 266 0.024
microtubule cytoskeleton organization GO:0000226 157 0.024
cellular homeostasis GO:0019725 240 0.024
negative regulation of protein modification process GO:0031400 163 0.024
skeletal system development GO:0001501 356 0.024
cellular nitrogen compound catabolic process GO:0044270 280 0.024
regulation of cell migration GO:0030334 219 0.024
Mouse
carbohydrate derivative biosynthetic process GO:1901137 183 0.024
generation of precursor metabolites and energy GO:0006091 103 0.024
protein localization to membrane GO:0072657 108 0.024
inflammatory response GO:0006954 244 0.024
sodium ion import GO:0097369 1 0.023
positive regulation of growth GO:0045927 104 0.023
cell recognition GO:0008037 83 0.023
Mouse
cellular response to organonitrogen compound GO:0071417 145 0.023
purine nucleotide metabolic process GO:0006163 302 0.023
learning GO:0007612 98 0.023
Mouse
regulation of cell projection organization GO:0031344 206 0.023
neuron apoptotic process GO:0051402 142 0.023
protein catabolic process GO:0030163 221 0.023
regulation of response to wounding GO:1903034 189 0.023
regulation of system process GO:0044057 200 0.023
ras protein signal transduction GO:0007265 77 0.023
establishment of protein localization to organelle GO:0072594 118 0.023
anatomical structure homeostasis GO:0060249 145 0.023
angiogenesis GO:0001525 201 0.023
regulation of mapk cascade GO:0043408 248 0.022
negative regulation of nervous system development GO:0051961 156 0.022
cellular response to abiotic stimulus GO:0071214 56 0.021
myeloid cell differentiation GO:0030099 233 0.021
muscle system process GO:0003012 141 0.021
regulation of homeostatic process GO:0032844 182 0.021
regulation of protein kinase activity GO:0045859 232 0.021
purine containing compound metabolic process GO:0072521 311 0.021
germ cell development GO:0007281 185 0.021
organic anion transport GO:0015711 137 0.021
carbohydrate metabolic process GO:0005975 230 0.021
immune response regulating cell surface receptor signaling pathway GO:0002768 80 0.021
regulation of muscle system process GO:0090257 80 0.020
leukocyte differentiation GO:0002521 342 0.020
glucose transport GO:0015758 56 0.020
response to extracellular stimulus GO:0009991 127 0.020
regulation of cell motility GO:2000145 236 0.020
Mouse
cellular protein complex assembly GO:0043623 116 0.020
response to inorganic substance GO:0010035 96 0.020
organophosphate biosynthetic process GO:0090407 122 0.020
regulation of purine nucleotide metabolic process GO:1900542 169 0.020
mapk cascade GO:0000165 281 0.020
regulation of cell size GO:0008361 72 0.020
carbohydrate derivative catabolic process GO:1901136 231 0.020
regulation of neuron differentiation GO:0045664 281 0.019
regulation of neuron projection development GO:0010975 169 0.019
muscle cell differentiation GO:0042692 261 0.019
striated muscle tissue development GO:0014706 293 0.019
camp metabolic process GO:0046058 40 0.019
protein import into nucleus GO:0006606 95 0.019
purine ribonucleotide biosynthetic process GO:0009152 59 0.019
negative regulation of immune system process GO:0002683 209 0.019
establishment or maintenance of cell polarity GO:0007163 86 0.019
rhythmic process GO:0048511 174 0.019
exocytosis GO:0006887 121 0.019
meiotic cell cycle process GO:1903046 77 0.019
sensory perception of mechanical stimulus GO:0050954 107 0.019
Mouse
regulation of hormone levels GO:0010817 211 0.018
peptidyl tyrosine modification GO:0018212 145 0.018
negative regulation of cell proliferation GO:0008285 296 0.018
developmental maturation GO:0021700 193 0.018
regulation of cellular catabolic process GO:0031329 242 0.018
circadian sleep wake cycle rem sleep GO:0042747 1 0.018
positive regulation of secretion by cell GO:1903532 114 0.018
protein import GO:0017038 101 0.018
nucleotide biosynthetic process GO:0009165 78 0.018
skeletal muscle organ development GO:0060538 163 0.018
second messenger mediated signaling GO:0019932 73 0.018
intracellular protein transport GO:0006886 204 0.018
Yeast
acetylcholine transport GO:0015870 2 0.017
monosaccharide transport GO:0015749 58 0.017
ossification GO:0001503 216 0.017
regulation of cell growth GO:0001558 91 0.017
regulation of leukocyte differentiation GO:1902105 159 0.017
anion transport GO:0006820 177 0.017
phototransduction GO:0007602 17 0.017
nuclear import GO:0051170 95 0.016
homeostasis of number of cells GO:0048872 210 0.016
spermatogenesis GO:0007283 284 0.016
inter male aggressive behavior GO:0002121 3 0.016
regulation of transferase activity GO:0051338 263 0.016
regulation of secretion by cell GO:1903530 249 0.016
single organismal cell cell adhesion GO:0016337 131 0.016
carbohydrate homeostasis GO:0033500 128 0.016
nucleocytoplasmic transport GO:0006913 139 0.016
striated muscle contraction GO:0006941 45 0.016
protein autophosphorylation GO:0046777 61 0.016
ribonucleotide catabolic process GO:0009261 208 0.016
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.016
protein processing GO:0016485 163 0.016
embryonic organ morphogenesis GO:0048562 276 0.016
digestive tract development GO:0048565 190 0.016
circadian rhythm GO:0007623 114 0.016
cellularization GO:0007349 1 0.016
adult walking behavior GO:0007628 41 0.016
sodium ion transport GO:0006814 73 0.016
regulation of ion homeostasis GO:2000021 64 0.016
development of primary sexual characteristics GO:0045137 143 0.016
protein maturation GO:0051604 176 0.016
osteoclast differentiation GO:0030316 62 0.016
regulation of calcium ion transport GO:0051924 69 0.016
response to acid chemical GO:0001101 111 0.016
regulation of protein complex assembly GO:0043254 83 0.015
nucleotide metabolic process GO:0009117 332 0.015
response to pain GO:0048265 26 0.015
single organism cell adhesion GO:0098602 156 0.015
positive regulation of cytosolic calcium ion concentration GO:0007204 65 0.015
peptide transport GO:0015833 133 0.015
detection of visible light GO:0009584 14 0.015
regulation of ion transmembrane transport GO:0034765 119 0.015
nucleoside metabolic process GO:0009116 246 0.015
immune response regulating signaling pathway GO:0002764 125 0.015
memory GO:0007613 58 0.015
detection of stimulus involved in sensory perception GO:0050906 44 0.015
cyclic nucleotide biosynthetic process GO:0009190 44 0.015
regulation of protein complex disassembly GO:0043244 28 0.015
negative regulation of organelle organization GO:0010639 90 0.015
mitotic cell cycle process GO:1903047 159 0.015
regionalization GO:0003002 337 0.015
norepinephrine secretion GO:0048243 2 0.015
compound eye development GO:0048749 1 0.015
fat cell differentiation GO:0045444 160 0.015
protein localization to nucleus GO:0034504 121 0.014
neuron death GO:0070997 154 0.014
hematopoietic progenitor cell differentiation GO:0002244 143 0.014
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.014
cellular response to transforming growth factor beta stimulus GO:0071560 88 0.014
adult behavior GO:0030534 135 0.014
positive regulation of secretion GO:0051047 130 0.014
cellular component assembly involved in morphogenesis GO:0010927 139 0.014
male gamete generation GO:0048232 285 0.014
nuclear transport GO:0051169 139 0.014
posttranscriptional regulation of gene expression GO:0010608 155 0.014
connective tissue development GO:0061448 179 0.014
regulation of apoptotic signaling pathway GO:2001233 197 0.014
transition metal ion transport GO:0000041 38 0.014
negative regulation of camp mediated signaling GO:0043951 3 0.014
lipid localization GO:0010876 126 0.014
intrinsic apoptotic signaling pathway GO:0097193 132 0.014
developmental growth involved in morphogenesis GO:0060560 138 0.014
peptide secretion GO:0002790 114 0.014
membrane lipid metabolic process GO:0006643 53 0.013
meiotic cell cycle GO:0051321 122 0.013
cellular carbohydrate metabolic process GO:0044262 119 0.013
response to peptide GO:1901652 136 0.013
cellular response to lipid GO:0071396 145 0.013
response to insulin GO:0032868 100 0.013
positive regulation of cellular component biogenesis GO:0044089 94 0.013
cell fate commitment GO:0045165 210 0.013
regulation of myeloid leukocyte differentiation GO:0002761 58 0.013
purine ribonucleotide catabolic process GO:0009154 208 0.013
ribose phosphate biosynthetic process GO:0046390 59 0.013
regulation of proteolysis GO:0030162 164 0.013
actin polymerization or depolymerization GO:0008154 54 0.013
lipid biosynthetic process GO:0008610 179 0.013
regulation of extrinsic apoptotic signaling pathway GO:2001236 77 0.013
protein modification by small protein conjugation or removal GO:0070647 207 0.013
ribonucleotide biosynthetic process GO:0009260 59 0.013
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.013
inclusion body assembly GO:0070841 3 0.013
defecation GO:0030421 1 0.013
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.013
circulatory system process GO:0003013 197 0.013
mitochondrion organization GO:0007005 134 0.013
deltoid tuberosity development GO:0035993 3 0.013
organelle localization GO:0051640 179 0.013
developmental cell growth GO:0048588 84 0.013
purine containing compound catabolic process GO:0072523 213 0.013
regulation of reactive oxygen species metabolic process GO:2000377 40 0.013
regulation of nucleotide metabolic process GO:0006140 169 0.013
vesicle organization GO:0016050 60 0.013
cellular protein catabolic process GO:0044257 155 0.013
acid secretion GO:0046717 33 0.013
regulation of neurotransmitter secretion GO:0046928 29 0.013
protein modification by small protein conjugation GO:0032446 187 0.013
protein complex disassembly GO:0043241 40 0.013
forebrain development GO:0030900 302 0.013
cellular response to peptide hormone stimulus GO:0071375 92 0.012
dicarboxylic acid transport GO:0006835 29 0.012
regulation of cell adhesion GO:0030155 154 0.012
meiotic nuclear division GO:0007126 115 0.012
regulation of muscle contraction GO:0006937 49 0.012
negative regulation of molecular function GO:0044092 258 0.012
regulation of actin polymerization or depolymerization GO:0008064 45 0.012
glycosyl compound metabolic process GO:1901657 246 0.012
intracellular mrna localization GO:0008298 4 0.012
positive regulation of vasoconstriction GO:0045907 4 0.012
establishment of organelle localization GO:0051656 122 0.012
asymmetric stem cell division GO:0098722 3 0.012
regulation of calcium ion transmembrane transporter activity GO:1901019 20 0.012
regulation of intracellular transport GO:0032386 159 0.012
response to peptide hormone GO:0043434 127 0.012
purine nucleotide biosynthetic process GO:0006164 65 0.012
nucleoside phosphate biosynthetic process GO:1901293 79 0.012
cellular macromolecule catabolic process GO:0044265 206 0.012
regulation of muscle tissue development GO:1901861 97 0.012
cell division GO:0051301 120 0.012
immune response activating cell surface receptor signaling pathway GO:0002429 72 0.012
cytosolic calcium ion homeostasis GO:0051480 70 0.012
detection of mechanical stimulus involved in sensory perception of pain GO:0050966 4 0.012
peptidyl lysine modification GO:0018205 77 0.012
negative regulation of homeostatic process GO:0032845 71 0.012
regulation of establishment of protein localization GO:0070201 181 0.012
amide transport GO:0042886 138 0.012
organelle fission GO:0048285 170 0.012
regulation of peptidyl tyrosine phosphorylation GO:0050730 93 0.012
response to oxidative stress GO:0006979 123 0.012
small gtpase mediated signal transduction GO:0007264 97 0.012
immune effector process GO:0002252 321 0.012
regulation of cytokine production GO:0001817 266 0.012
asymmetric neuroblast division GO:0055059 1 0.012
positive regulation of necrotic cell death GO:0010940 1 0.012
response to mineralocorticoid GO:0051385 1 0.012
protein depolymerization GO:0051261 34 0.012
mating GO:0007618 27 0.012
dna metabolic process GO:0006259 303 0.011
tissue homeostasis GO:0001894 115 0.011
negative regulation of phosphate metabolic process GO:0045936 184 0.011
organelle assembly GO:0070925 177 0.011
Yeast
positive regulation of cell development GO:0010720 237 0.011
reactive oxygen species biosynthetic process GO:1903409 8 0.011
adenylate cyclase modulating g protein coupled receptor signaling pathway GO:0007188 54 0.011
cytokine production GO:0001816 319 0.011
endocytosis GO:0006897 168 0.011
Yeast
cellular response to hormone stimulus GO:0032870 150 0.011
lipid transport GO:0006869 98 0.011
calcium ion transport into cytosol GO:0060402 48 0.011
negative regulation of cell development GO:0010721 169 0.011
fatty acid metabolic process GO:0006631 121 0.011
endomembrane system organization GO:0010256 147 0.011
Mouse
respiratory tube development GO:0030323 167 0.011
multi multicellular organism process GO:0044706 109 0.011
regulation of cyclic nucleotide metabolic process GO:0030799 40 0.011
mesodermal cell migration GO:0008078 4 0.011
response to temperature stimulus GO:0009266 55 0.011
axoneme assembly GO:0035082 15 0.011
mitotic cytokinesis GO:0000281 4 0.011
regulation of circadian sleep wake cycle GO:0042749 3 0.011
axon guidance GO:0007411 141 0.011
activation of immune response GO:0002253 138 0.011
regulation of multi organism process GO:0043900 111 0.011
regulation of vasculature development GO:1901342 88 0.011
diterpenoid metabolic process GO:0016101 24 0.011
regulation of ras protein signal transduction GO:0046578 114 0.011
epithelial cell proliferation GO:0050673 174 0.011
positive regulation of protein transport GO:0051222 93 0.011
positive regulation of transferase activity GO:0051347 167 0.011
heart contraction GO:0060047 93 0.011
positive regulation of organelle organization GO:0010638 128 0.011
organophosphate catabolic process GO:0046434 232 0.011
negative regulation of phosphorylation GO:0042326 166 0.011
cholesterol metabolic process GO:0008203 56 0.010
epithelial cell migration GO:0010631 63 0.010
peptidyl serine modification GO:0018209 83 0.010
organic hydroxy compound biosynthetic process GO:1901617 77 0.010
skeletal system morphogenesis GO:0048705 203 0.010
engulfment of apoptotic cell GO:0043652 3 0.010
embryonic genitalia morphogenesis GO:0030538 4 0.010
negative regulation of protein complex disassembly GO:0043242 22 0.010
regulation of blood circulation GO:1903522 93 0.010
b cell activation GO:0042113 161 0.010
nucleoside phosphate catabolic process GO:1901292 222 0.010
regulation of norepinephrine secretion GO:0014061 2 0.010
response to corticosterone GO:0051412 1 0.010
purine nucleoside catabolic process GO:0006152 205 0.010
epithelial tube morphogenesis GO:0060562 303 0.010
cellular amide metabolic process GO:0043603 58 0.010
hexose transport GO:0008645 56 0.010
protein ubiquitination GO:0016567 171 0.010
regulation of nucleotide biosynthetic process GO:0030808 34 0.010
regulation of protein targeting GO:1903533 61 0.010
gliogenesis GO:0042063 141 0.010
cell cell adhesion GO:0098609 41 0.010

Atp8a2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.045
nervous system disease DOID:863 0 0.045
sensory system disease DOID:0050155 0 0.021
eye and adnexa disease DOID:1492 0 0.019
eye disease DOID:5614 0 0.019
cancer DOID:162 0 0.013
disease of cellular proliferation DOID:14566 0 0.013
organ system cancer DOID:0050686 0 0.011
retinal disease DOID:5679 0 0.011
retinal degeneration DOID:8466 0 0.011
musculoskeletal system disease DOID:17 0 0.011