Mus musculus

170 known processes

Lrp4

low density lipoprotein receptor-related protein 4

(Aliases: D230026E03,Megf7,6430526J12Rik,mdig)

Lrp4 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
appendage morphogenesis GO:0035107 149 0.422
regionalization GO:0003002 337 0.396
nitrogen compound transport GO:0071705 271 0.387
Mouse
mapk cascade GO:0000165 281 0.371
Mouse
limb development GO:0060173 166 0.323
urogenital system development GO:0001655 261 0.320
appendage development GO:0048736 166 0.309
skeletal system morphogenesis GO:0048705 203 0.291
Mouse
limb morphogenesis GO:0035108 149 0.284
epithelial tube morphogenesis GO:0060562 303 0.282
Mouse
skeletal system development GO:0001501 356 0.275
Mouse
embryonic limb morphogenesis GO:0030326 126 0.274
branching morphogenesis of an epithelial tube GO:0048754 159 0.254
Mouse
wnt signaling pathway GO:0016055 188 0.246
embryonic appendage morphogenesis GO:0035113 126 0.232
embryonic organ morphogenesis GO:0048562 276 0.231
Mouse
neural tube formation GO:0001841 108 0.222
Mouse
morphogenesis of embryonic epithelium GO:0016331 159 0.221
Mouse
telencephalon development GO:0021537 186 0.217
Mouse
forebrain development GO:0030900 302 0.216
Mouse
formation of radial glial scaffolds GO:0021943 4 0.216
Mouse
kidney development GO:0001822 213 0.214
axonogenesis GO:0007409 274 0.211
regulation of kinase activity GO:0043549 249 0.205
Mouse
renal system development GO:0072001 225 0.204
regulation of protein kinase activity GO:0045859 232 0.201
Mouse
positive regulation of programmed cell death GO:0043068 218 0.190
Mouse
positive regulation of apoptotic process GO:0043065 217 0.188
Mouse
peptide transport GO:0015833 133 0.182
Mouse
muscle tissue development GO:0060537 308 0.181
Mouse
sensory organ morphogenesis GO:0090596 242 0.175
Mouse
ear development GO:0043583 200 0.165
morphogenesis of a branching epithelium GO:0061138 193 0.162
Mouse
cellular ketone metabolic process GO:0042180 84 0.162
regulation of cellular component size GO:0032535 121 0.157
camera type eye development GO:0043010 266 0.156
Mouse
sensory perception GO:0007600 245 0.156
canonical wnt signaling pathway GO:0060070 130 0.150
Human Mouse
regulation of organ morphogenesis GO:2000027 144 0.145
Mouse
digestive tract morphogenesis GO:0048546 147 0.145
Mouse
morphogenesis of a branching structure GO:0001763 203 0.143
Mouse
regulation of canonical wnt signaling pathway GO:0060828 82 0.141
Human
ras protein signal transduction GO:0007265 77 0.141
blood vessel morphogenesis GO:0048514 285 0.139
Mouse
wnt signaling pathway involved in somitogenesis GO:0090244 4 0.137
Mouse
pallium development GO:0021543 120 0.136
Mouse
amine metabolic process GO:0009308 45 0.133
regulation of cellular catabolic process GO:0031329 242 0.132
Mouse
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.130
Mouse
organonitrogen compound catabolic process GO:1901565 264 0.130
digestive tract development GO:0048565 190 0.130
Mouse
leukocyte differentiation GO:0002521 342 0.128
respiratory system development GO:0060541 190 0.128
Mouse
lipid biosynthetic process GO:0008610 179 0.127
response to nutrient levels GO:0031667 109 0.124
Mouse
glial cell differentiation GO:0010001 131 0.124
Mouse
intracellular protein transport GO:0006886 204 0.122
Mouse
digestive system development GO:0055123 200 0.121
Mouse
positive regulation of kinase activity GO:0033674 155 0.121
Mouse
regulation of mapk cascade GO:0043408 248 0.120
Mouse
establishment of vesicle localization GO:0051650 81 0.120
odontogenesis GO:0042476 78 0.118
muscle cell differentiation GO:0042692 261 0.116
apoptotic signaling pathway GO:0097190 306 0.115
vesicle localization GO:0051648 86 0.114
tube formation GO:0035148 140 0.113
Mouse
neural tube development GO:0021915 160 0.111
Mouse
central nervous system neuron differentiation GO:0021953 162 0.110
organic hydroxy compound metabolic process GO:1901615 203 0.109
Mouse
mammary placode formation GO:0060596 4 0.108
Mouse
membrane organization GO:0061024 245 0.108
regulation of apoptotic signaling pathway GO:2001233 197 0.108
negative regulation of neuron differentiation GO:0045665 101 0.107
nucleoside catabolic process GO:0009164 206 0.107
odontogenesis of dentin containing tooth GO:0042475 66 0.107
regulation of cellular amino acid metabolic process GO:0006521 5 0.106
cell fate commitment GO:0045165 210 0.106
connective tissue development GO:0061448 179 0.106
Mouse
bone morphogenesis GO:0060349 78 0.105
Mouse
positive regulation of cell death GO:0010942 224 0.105
Mouse
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.105
embryonic skeletal system development GO:0048706 120 0.105
cell adhesion GO:0007155 329 0.104
regulation of wnt signaling pathway GO:0030111 123 0.103
cartilage development GO:0051216 140 0.103
Mouse
ear morphogenesis GO:0042471 118 0.102
cellular amine metabolic process GO:0044106 44 0.100
cerebral cortex development GO:0021987 86 0.098
Mouse
genitalia morphogenesis GO:0035112 11 0.098
Mouse
purine nucleoside metabolic process GO:0042278 241 0.096
actin cytoskeleton organization GO:0030036 220 0.096
Mouse
palate development GO:0060021 76 0.095
Mouse
planar cell polarity pathway involved in pericardium morphogenesis GO:0061354 2 0.094
Mouse
inner ear morphogenesis GO:0042472 101 0.094
regulation of cellular component biogenesis GO:0044087 181 0.094
wnt signaling pathway involved in forebrain neuroblast division GO:0021874 2 0.093
Mouse
cellular amino acid metabolic process GO:0006520 103 0.093
regulation of hydrolase activity GO:0051336 246 0.092
Mouse
axis elongation involved in somitogenesis GO:0090245 4 0.092
Mouse
negative regulation of cellular component organization GO:0051129 194 0.092
negative regulation of wnt signaling pathway involved in heart development GO:0003308 4 0.091
Mouse
striated muscle tissue development GO:0014706 293 0.091
Mouse
primary neural tube formation GO:0014020 95 0.090
Mouse
positive regulation of mapk cascade GO:0043410 170 0.089
Mouse
protein localization to organelle GO:0033365 185 0.089
Mouse
myeloid cell differentiation GO:0030099 233 0.088
cardiac right atrium morphogenesis GO:0003213 3 0.088
Mouse
embryonic epithelial tube formation GO:0001838 130 0.087
Mouse
negative regulation of planar cell polarity pathway involved in heart morphogenesis GO:2000160 1 0.087
Mouse
wnt signaling pathway planar cell polarity pathway GO:0060071 27 0.086
Mouse
rho protein signal transduction GO:0007266 32 0.086
negative regulation of molecular function GO:0044092 258 0.086
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.086
glycosyl compound catabolic process GO:1901658 206 0.085
endodermal cell fate specification GO:0001714 4 0.085
synaptic transmission GO:0007268 329 0.084
negative regulation of planar cell polarity pathway involved in pericardium morphogenesis GO:2000166 1 0.084
Mouse
nucleotide metabolic process GO:0009117 332 0.084
negative regulation of cell morphogenesis involved in differentiation GO:0010771 48 0.084
positive regulation of protein phosphorylation GO:0001934 242 0.083
Mouse
stem cell differentiation GO:0048863 268 0.083
Mouse
positive regulation of protein modification process GO:0031401 299 0.083
Mouse
purine nucleoside triphosphate metabolic process GO:0009144 226 0.081
ribonucleotide metabolic process GO:0009259 291 0.081
regulation of transferase activity GO:0051338 263 0.080
Mouse
nucleoside triphosphate metabolic process GO:0009141 230 0.078
establishment of organelle localization GO:0051656 122 0.078
regulation of cellular ketone metabolic process GO:0010565 66 0.078
ossification GO:0001503 216 0.077
Human Mouse
ribose phosphate metabolic process GO:0019693 291 0.077
organic cyclic compound catabolic process GO:1901361 295 0.077
insulin secretion GO:0030073 89 0.076
Mouse
regulation of planar cell polarity pathway involved in ventricular septum morphogenesis GO:2000148 1 0.076
Mouse
organic acid biosynthetic process GO:0016053 86 0.075
gland development GO:0048732 330 0.075
Mouse
response to organonitrogen compound GO:0010243 246 0.075
Mouse
regulation of stem cell proliferation GO:0072091 78 0.073
Mouse
positive regulation of protein kinase activity GO:0045860 144 0.072
Mouse
gastrulation GO:0007369 116 0.072
Mouse
cellular chemical homeostasis GO:0055082 215 0.072
Mouse
embryonic digit morphogenesis GO:0042733 56 0.071
positive regulation of cellular amine metabolic process GO:0033240 5 0.071
endocytosis GO:0006897 168 0.071
Mouse
purine ribonucleoside catabolic process GO:0046130 205 0.070
cellular homeostasis GO:0019725 240 0.070
Mouse
epidermis development GO:0008544 187 0.070
regulation of membrane potential GO:0042391 192 0.068
epithelial cell proliferation GO:0050673 174 0.068
Mouse
jnk cascade GO:0007254 72 0.068
purine containing compound catabolic process GO:0072523 213 0.067
cellular nitrogen compound catabolic process GO:0044270 280 0.067
non canonical wnt signaling pathway GO:0035567 33 0.067
Mouse
purine ribonucleoside metabolic process GO:0046128 241 0.067
stem cell development GO:0048864 219 0.067
Mouse
dendrite development GO:0016358 115 0.066
Rat
heterocycle catabolic process GO:0046700 280 0.066
regulation of hormone levels GO:0010817 211 0.066
Mouse
cell type specific apoptotic process GO:0097285 268 0.066
purine nucleotide catabolic process GO:0006195 211 0.066
planar cell polarity pathway involved in cardiac muscle tissue morphogenesis GO:0061350 2 0.065
Mouse
aromatic compound catabolic process GO:0019439 286 0.065
neuronal action potential GO:0019228 54 0.064
regulation of protein serine threonine kinase activity GO:0071900 157 0.064
Mouse
gliogenesis GO:0042063 141 0.063
Mouse
regulation of planar cell polarity pathway involved in outflow tract morphogenesis GO:2000163 1 0.063
Mouse
dna metabolic process GO:0006259 303 0.063
cellular response to growth factor stimulus GO:0071363 197 0.063
nuclear import GO:0051170 95 0.063
Mouse
neuron apoptotic process GO:0051402 142 0.063
fat cell differentiation GO:0045444 160 0.063
Mouse
skeletal muscle organ development GO:0060538 163 0.063
ribonucleoside catabolic process GO:0042454 206 0.062
skin development GO:0043588 220 0.061
ribonucleoside triphosphate catabolic process GO:0009203 199 0.061
morphogenesis of a polarized epithelium GO:0001738 37 0.061
stress activated mapk cascade GO:0051403 80 0.061
peptide hormone secretion GO:0030072 109 0.061
Mouse
small molecule biosynthetic process GO:0044283 132 0.061
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.061
nucleoside triphosphate catabolic process GO:0009143 205 0.060
regulation of neuron differentiation GO:0045664 281 0.060
axon guidance GO:0007411 141 0.060
small gtpase mediated signal transduction GO:0007264 97 0.060
embryonic skeletal system morphogenesis GO:0048704 91 0.059
forebrain radial glial cell differentiation GO:0021861 4 0.059
Mouse
telencephalon cell migration GO:0022029 55 0.059
Mouse
chemotaxis GO:0006935 247 0.058
organophosphate catabolic process GO:0046434 232 0.057
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.057
purine containing compound metabolic process GO:0072521 311 0.056
negative regulation of protein metabolic process GO:0051248 282 0.056
cellular response to lipid GO:0071396 145 0.056
neural tube closure GO:0001843 90 0.056
Mouse
purine nucleoside triphosphate catabolic process GO:0009146 203 0.056
negative regulation of cell development GO:0010721 169 0.056
organelle localization GO:0051640 179 0.056
regulation of cell adhesion GO:0030155 154 0.055
planar cell polarity pathway involved in ventricular septum morphogenesis GO:0061348 2 0.055
Mouse
macromolecule catabolic process GO:0009057 281 0.055
Mouse
purine ribonucleotide metabolic process GO:0009150 290 0.055
cell migration involved in gastrulation GO:0042074 13 0.054
Mouse
defense response to other organism GO:0098542 197 0.054
neuron projection guidance GO:0097485 141 0.054
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.054
peptidyl tyrosine modification GO:0018212 145 0.054
Mouse
positive regulation of cellular component biogenesis GO:0044089 94 0.054
negative regulation of bmp signaling pathway GO:0030514 35 0.054
cytoplasmic transport GO:0016482 234 0.053
Mouse
mammary gland epithelium development GO:0061180 65 0.053
Mouse
monocarboxylic acid biosynthetic process GO:0072330 61 0.053
ribonucleotide catabolic process GO:0009261 208 0.053
stress activated protein kinase signaling cascade GO:0031098 81 0.053
segmentation GO:0035282 93 0.053
Mouse
g protein coupled receptor signaling pathway GO:0007186 243 0.053
nucleoside phosphate metabolic process GO:0006753 338 0.052
somite development GO:0061053 81 0.052
Mouse
intraspecies interaction between organisms GO:0051703 21 0.052
regulation of cell migration GO:0030334 219 0.051
Mouse
protein localization to nucleus GO:0034504 121 0.051
Mouse
planar cell polarity pathway involved in heart morphogenesis GO:0061346 3 0.051
Mouse
regulation of purine nucleotide catabolic process GO:0033121 122 0.051
nucleoside metabolic process GO:0009116 246 0.051
positive regulation of nervous system development GO:0051962 221 0.051
Mouse
negative regulation of nervous system development GO:0051961 156 0.051
anatomical structure homeostasis GO:0060249 145 0.051
Mouse
protein localization to membrane GO:0072657 108 0.051
non canonical wnt signaling pathway involved in heart development GO:0061341 3 0.050
Mouse
carbohydrate derivative catabolic process GO:1901136 231 0.049
positive regulation of cell development GO:0010720 237 0.049
regulation of peptide secretion GO:0002791 77 0.049
Mouse
positive regulation of neuron apoptotic process GO:0043525 25 0.049
regulation of nucleoside metabolic process GO:0009118 130 0.049
cardiac chamber development GO:0003205 108 0.049
Mouse
regulation of actin cytoskeleton organization GO:0032956 84 0.048
Mouse
mammary gland duct morphogenesis GO:0060603 38 0.048
Mouse
lung development GO:0030324 164 0.048
determination of left right symmetry GO:0007368 80 0.048
Mouse
embryonic genitalia morphogenesis GO:0030538 4 0.048
myotube differentiation GO:0014902 105 0.048
t cell activation GO:0042110 289 0.048
glucose homeostasis GO:0042593 128 0.048
Mouse
eye photoreceptor cell differentiation GO:0001754 41 0.048
ribonucleoside metabolic process GO:0009119 245 0.047
regulation of lymphocyte activation GO:0051249 240 0.047
purine nucleoside catabolic process GO:0006152 205 0.047
regulation of cell cycle GO:0051726 281 0.047
protein targeting GO:0006605 143 0.047
Mouse
regulation of ras protein signal transduction GO:0046578 114 0.047
nucleobase containing small molecule metabolic process GO:0055086 352 0.047
amide transport GO:0042886 138 0.047
Mouse
cellular lipid metabolic process GO:0044255 323 0.046
muscle system process GO:0003012 141 0.046
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.046
anion transport GO:0006820 177 0.046
negative regulation of cell projection organization GO:0031345 56 0.046
somatic stem cell maintenance GO:0035019 47 0.046
Mouse
response to growth factor GO:0070848 198 0.045
learning or memory GO:0007611 148 0.045
cell growth GO:0016049 130 0.045
regulation of striated muscle cell differentiation GO:0051153 81 0.045
transmembrane transport GO:0055085 412 0.045
single organism nuclear import GO:1902593 95 0.045
Mouse
purine ribonucleotide catabolic process GO:0009154 208 0.045
synapse organization GO:0050808 125 0.045
response to organic cyclic compound GO:0014070 198 0.045
Mouse
regulation of cellular response to stress GO:0080135 159 0.045
negative regulation of apoptotic signaling pathway GO:2001234 104 0.045
regulation of binding GO:0051098 111 0.044
Mouse
establishment of synaptic vesicle localization GO:0097480 57 0.044
alcohol metabolic process GO:0006066 116 0.044
Mouse
mesenchyme development GO:0060485 152 0.044
Mouse
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.044
stem cell proliferation GO:0072089 117 0.044
Mouse
photoreceptor cell differentiation GO:0046530 52 0.044
renal tubule development GO:0061326 87 0.044
regulation of defense response GO:0031347 233 0.044
bmp signaling pathway GO:0030509 93 0.043
regulation of endocytosis GO:0030100 69 0.043
protein import into nucleus GO:0006606 95 0.043
Mouse
embryonic camera type eye development GO:0031076 36 0.043
Mouse
male gamete generation GO:0048232 285 0.043
regulation of neuron projection development GO:0010975 169 0.042
innate immune response GO:0045087 157 0.042
lymphocyte differentiation GO:0030098 242 0.042
negative regulation of sterol transport GO:0032372 4 0.042
Mouse
nucleotide catabolic process GO:0009166 217 0.042
sulfur compound metabolic process GO:0006790 100 0.042
somitogenesis GO:0001756 69 0.042
Mouse
negative regulation of cardiac chamber morphogenesis GO:1901220 2 0.042
Mouse
regulation of establishment of planar polarity GO:0090175 28 0.042
Mouse
metanephros development GO:0001656 79 0.042
negative regulation of cell proliferation GO:0008285 296 0.042
Mouse
microtubule based process GO:0007017 236 0.042
response to oxygen levels GO:0070482 62 0.042
purine nucleotide metabolic process GO:0006163 302 0.041
glycosyl compound metabolic process GO:1901657 246 0.041
synaptic vesicle transport GO:0048489 57 0.041
negative regulation of planar cell polarity pathway involved in ventricular septum morphogenesis GO:2000149 1 0.041
Mouse
asymmetric stem cell division GO:0098722 3 0.041
response to extracellular stimulus GO:0009991 127 0.040
Mouse
neuron migration GO:0001764 122 0.040
bone development GO:0060348 120 0.040
Mouse
negative regulation of planar cell polarity pathway involved in cardiac right atrium morphogenesis GO:2000162 1 0.040
Mouse
kidney morphogenesis GO:0060993 83 0.040
mesonephric tubule development GO:0072164 94 0.040
ribonucleoside triphosphate metabolic process GO:0009199 220 0.040
regulation of cellular amine metabolic process GO:0033238 20 0.040
carboxylic acid biosynthetic process GO:0046394 86 0.040
cell proliferation in hindbrain GO:0021534 10 0.040
Mouse
regulation of mesenchymal cell proliferation GO:0010464 37 0.040
Mouse
negative regulation of protein modification process GO:0031400 163 0.040
establishment of planar polarity GO:0001736 28 0.040
regulation of cell projection organization GO:0031344 206 0.040
epithelial cell morphogenesis GO:0003382 41 0.040
spinal cord development GO:0021510 81 0.039
regulation of anatomical structure size GO:0090066 178 0.039
leukocyte proliferation GO:0070661 172 0.039
cell chemotaxis GO:0060326 81 0.039
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.039
Mouse
forelimb morphogenesis GO:0035136 40 0.039
Mouse
retina development in camera type eye GO:0060041 119 0.039
Mouse
developmental growth involved in morphogenesis GO:0060560 138 0.039
Mouse
cellular protein complex assembly GO:0043623 116 0.039
leukocyte migration GO:0050900 124 0.039
face morphogenesis GO:0060325 29 0.039
Mouse
carbohydrate homeostasis GO:0033500 128 0.038
Mouse
spermatogenesis GO:0007283 284 0.038
positive regulation of cellular catabolic process GO:0031331 148 0.038
Mouse
canonical wnt signaling pathway involved in regulation of cell proliferation GO:0044340 3 0.038
Mouse
positive regulation of hydrolase activity GO:0051345 148 0.038
monocarboxylic acid metabolic process GO:0032787 191 0.038
regulation of organelle organization GO:0033043 289 0.037
Mouse
cardiac muscle tissue morphogenesis GO:0055008 44 0.037
Mouse
hormone secretion GO:0046879 128 0.037
Mouse
myeloid leukocyte differentiation GO:0002573 119 0.037
respiratory tube development GO:0030323 167 0.037
positive regulation of endocytosis GO:0045807 42 0.037
negative regulation of platelet derived growth factor receptor beta signaling pathway GO:2000587 2 0.037
Mouse
posttranscriptional regulation of gene expression GO:0010608 155 0.037
protein catabolic process GO:0030163 221 0.037
Mouse
cell junction assembly GO:0034329 52 0.037
regulation of fat cell differentiation GO:0045598 81 0.036
Mouse
regulation of secretion GO:0051046 274 0.036
Mouse
cardiac septum morphogenesis GO:0060411 46 0.036
Mouse
positive regulation of wnt signaling pathway GO:0030177 45 0.036
intrinsic apoptotic signaling pathway GO:0097193 132 0.036
kidney epithelium development GO:0072073 121 0.036
asymmetric neuroblast division GO:0055059 1 0.036
epithelial to mesenchymal transition GO:0001837 47 0.036
transmission of nerve impulse GO:0019226 76 0.036
regulation of cardiac chamber morphogenesis GO:1901219 2 0.036
Mouse
neuron death GO:0070997 154 0.035
diencephalon development GO:0021536 63 0.035
Mouse
photoreceptor cell development GO:0042461 40 0.035
lipid homeostasis GO:0055088 63 0.035
ureteric bud development GO:0001657 94 0.035
rac protein signal transduction GO:0016601 13 0.035
cardiac septum development GO:0003279 59 0.035
Mouse
intracellular cholesterol transport GO:0032367 3 0.035
Mouse
cognition GO:0050890 149 0.035
regulation of actin filament based process GO:0032970 99 0.035
Mouse
planar cell polarity pathway involved in cardiac right atrium morphogenesis GO:0061349 2 0.035
Mouse
peptide secretion GO:0002790 114 0.035
Mouse
neuroblast division GO:0055057 10 0.034
Mouse
positive regulation of innate immune response GO:0045089 80 0.034
gtp catabolic process GO:0006184 143 0.034
regulation of peptide hormone secretion GO:0090276 75 0.034
Mouse
mesenchymal cell differentiation GO:0048762 107 0.034
Mouse
mesonephros development GO:0001823 97 0.034
regulation of neuron death GO:1901214 134 0.034
oxidation reduction process GO:0055114 342 0.034
regulation of neuron apoptotic process GO:0043523 122 0.033
regulation of response to wounding GO:1903034 189 0.033
extrinsic apoptotic signaling pathway GO:0097191 126 0.033
regulation of vesicle mediated transport GO:0060627 139 0.033
dendritic spine maintenance GO:0097062 4 0.033
positive regulation of synaptic growth at neuromuscular junction GO:0045887 1 0.033
regulation of peptide transport GO:0090087 91 0.033
Mouse
somatic stem cell division GO:0048103 19 0.032
Mouse
limbic system development GO:0021761 72 0.032
regulation of system process GO:0044057 200 0.032
protein import GO:0017038 101 0.032
Mouse
oligodendrocyte differentiation GO:0048709 53 0.032
peptidyl tyrosine phosphorylation GO:0018108 143 0.032
Mouse
negative regulation of immune system process GO:0002683 209 0.032
forebrain cell migration GO:0021885 58 0.032
Mouse
regulation of intracellular protein transport GO:0033157 82 0.032
regulation of phospholipase a2 activity GO:0032429 3 0.032
Mouse
polarity specification of proximal distal axis GO:0010085 2 0.032
developmental cell growth GO:0048588 84 0.031
social behavior GO:0035176 21 0.031
protein modification by small protein conjugation GO:0032446 187 0.031
Mouse
regulation of protein catabolic process GO:0042176 108 0.031
Mouse
guanosine containing compound catabolic process GO:1901069 144 0.031
negative regulation of phosphorus metabolic process GO:0010563 184 0.031
axon ensheathment GO:0008366 76 0.031
homeostasis of number of cells GO:0048872 210 0.031
glial cell development GO:0021782 54 0.031
t cell differentiation GO:0030217 174 0.031
positive regulation of protein modification by small protein conjugation or removal GO:1903322 30 0.031
Mouse
b cell activation GO:0042113 161 0.031
determination of heart left right asymmetry GO:0061371 48 0.031
Mouse
negative regulation of epithelial cell proliferation GO:0050680 64 0.031
Mouse
establishment of tissue polarity GO:0007164 28 0.031
nephron development GO:0072006 109 0.031
nucleoside phosphate catabolic process GO:1901292 222 0.030
establishment of protein localization to organelle GO:0072594 118 0.030
Mouse
metencephalon development GO:0022037 89 0.030
Mouse
defense response to bacterium GO:0042742 119 0.030
protein kinase c activating g protein coupled receptor signaling pathway GO:0007205 4 0.030
regulation of ras gtpase activity GO:0032318 88 0.030
regulation of nucleotide catabolic process GO:0030811 122 0.030
receptor mediated endocytosis of low density lipoprotein particle involved in cholesterol transport GO:0090118 1 0.030
Mouse
nuclear division GO:0000280 158 0.030
positive regulation of neuron differentiation GO:0045666 141 0.030
regulation of stress activated mapk cascade GO:0032872 69 0.030
regulation of neural precursor cell proliferation GO:2000177 70 0.030
Mouse
regulation of epithelial cell proliferation GO:0050678 141 0.030
Mouse
lateral line system development GO:0048925 1 0.030
positive regulation of map kinase activity GO:0043406 84 0.030
Mouse
trachea cartilage morphogenesis GO:0060535 4 0.030
Mouse
cell division GO:0051301 120 0.030
Mouse
receptor mediated endocytosis GO:0006898 51 0.029
Mouse
neuron neuron synaptic transmission GO:0007270 69 0.029
negative regulation of planar cell polarity pathway involved in cardiac muscle tissue morphogenesis GO:2000151 1 0.029
Mouse
positive regulation of muscle cell differentiation GO:0051149 39 0.029
cerebellum morphogenesis GO:0021587 42 0.029
Mouse
planar cell polarity pathway involved in outflow tract morphogenesis GO:0061347 2 0.029
Mouse
negative regulation of cellular protein metabolic process GO:0032269 247 0.029
organonitrogen compound biosynthetic process GO:1901566 192 0.029
multi multicellular organism process GO:0044706 109 0.029
protein polymerization GO:0051258 57 0.029
regulation of bmp signaling pathway GO:0030510 60 0.029
regulation of cytoskeleton organization GO:0051493 122 0.029
Mouse
cellular response to extracellular stimulus GO:0031668 81 0.029
substrate dependent cerebral cortex tangential migration GO:0021825 3 0.029
engulfment of apoptotic cell GO:0043652 3 0.029
regulation of jnk cascade GO:0046328 62 0.029
tissue remodeling GO:0048771 102 0.029
Mouse
negative regulation of growth GO:0045926 99 0.029
tube closure GO:0060606 91 0.029
Mouse
hindbrain morphogenesis GO:0021575 46 0.029
Mouse
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 61 0.028
reactive oxygen species metabolic process GO:0072593 84 0.028
mammary gland morphogenesis GO:0060443 54 0.028
Mouse
cardiac chamber morphogenesis GO:0003206 93 0.028
Mouse
regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis GO:0072039 4 0.028
defecation GO:0030421 1 0.028
lipid localization GO:0010876 126 0.028
Mouse
cellular response to monosaccharide stimulus GO:0071326 47 0.028
Mouse
angiogenesis GO:0001525 201 0.028
Mouse
gonad development GO:0008406 141 0.028
negative regulation of fat cell differentiation GO:0045599 36 0.028
Mouse
muscle tissue morphogenesis GO:0060415 53 0.028
Mouse
mesenchymal cell development GO:0014031 93 0.028
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.028
Mouse
regulation of protein ubiquitination GO:0031396 52 0.028
Mouse
sensory system development GO:0048880 3 0.028
negative regulation of canonical wnt signaling pathway GO:0090090 51 0.027
Human
regulation of leukocyte differentiation GO:1902105 159 0.027
regulation of cytoplasmic transport GO:1903649 112 0.027
heart morphogenesis GO:0003007 178 0.027
Mouse
amino acid transport GO:0006865 61 0.027
canonical wnt signaling pathway involved in cardiac neural crest cell differentiation involved in heart development GO:0061310 1 0.027
Mouse
regulation of planar cell polarity pathway involved in cardiac muscle tissue morphogenesis GO:2000150 1 0.027
Mouse
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 61 0.027
formation of primary germ layer GO:0001704 77 0.027
regulation of peptidyl tyrosine phosphorylation GO:0050730 93 0.027
Mouse
mitotic cell cycle process GO:1903047 159 0.027
gtp metabolic process GO:0046039 144 0.027
positive regulation of cell activation GO:0050867 158 0.026
sensory perception of mechanical stimulus GO:0050954 107 0.026
negative regulation of phosphate metabolic process GO:0045936 184 0.026
positive regulation of epithelial cell proliferation involved in lung morphogenesis GO:0060501 3 0.026
regulation of circadian sleep wake cycle GO:0042749 3 0.026
regulation of intrinsic apoptotic signaling pathway GO:2001242 61 0.026
regulation of protein localization GO:0032880 231 0.026
lateral inhibition GO:0046331 1 0.026
learning GO:0007612 98 0.026
positive regulation of apoptotic signaling pathway GO:2001235 95 0.026
neuron projection extension GO:1990138 64 0.026
regulation of cell cycle process GO:0010564 160 0.026
immune effector process GO:0002252 321 0.026
alpha beta t cell activation GO:0046631 91 0.026

Lrp4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.100
musculoskeletal system disease DOID:17 0 0.100
connective tissue disease DOID:65 0 0.100
bone disease DOID:0080001 0 0.075
disease of metabolism DOID:0014667 0 0.075
nervous system disease DOID:863 0 0.035
diabetes mellitus DOID:9351 0 0.031
type 2 diabetes mellitus DOID:9352 0 0.031
carbohydrate metabolism disease DOID:0050013 0 0.031
glucose metabolism disease DOID:4194 0 0.031
acquired metabolic disease DOID:0060158 0 0.031