Mus musculus

0 known processes

Itm2a

integral membrane protein 2A

(Aliases: AW108051,Itm2,E25)

Itm2a biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular response to growth factor stimulus GO:0071363 197 0.090
negative regulation of molecular function GO:0044092 258 0.088
amine metabolic process GO:0009308 45 0.085
negative regulation of protein metabolic process GO:0051248 282 0.076
protein processing GO:0016485 163 0.066
extracellular structure organization GO:0043062 148 0.066
nitrogen compound transport GO:0071705 271 0.056
response to transforming growth factor beta GO:0071559 88 0.053
cellular amino acid metabolic process GO:0006520 103 0.052
synaptic transmission GO:0007268 329 0.046
regulation of cellular ketone metabolic process GO:0010565 66 0.044
regulation of cellular amino acid metabolic process GO:0006521 5 0.043
protein maturation GO:0051604 176 0.043
cellular ketone metabolic process GO:0042180 84 0.041
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.039
positive regulation of cell death GO:0010942 224 0.039
monocarboxylic acid metabolic process GO:0032787 191 0.038
action potential GO:0001508 78 0.038
extracellular matrix organization GO:0030198 147 0.037
negative regulation of cellular protein metabolic process GO:0032269 247 0.037
positive regulation of cellular amine metabolic process GO:0033240 5 0.037
macromolecule catabolic process GO:0009057 281 0.037
transmembrane transport GO:0055085 412 0.036
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.035
glycoprotein metabolic process GO:0009100 116 0.035
ras protein signal transduction GO:0007265 77 0.034
response to organic cyclic compound GO:0014070 198 0.034
cation transport GO:0006812 399 0.033
multicellular organism growth GO:0035264 161 0.033
mitochondrion organization GO:0007005 134 0.033
cellular response to hormone stimulus GO:0032870 150 0.033
positive regulation of programmed cell death GO:0043068 218 0.032
transmission of nerve impulse GO:0019226 76 0.032
cellular chemical homeostasis GO:0055082 215 0.031
dna metabolic process GO:0006259 303 0.031
neural tube development GO:0021915 160 0.031
regulation of response to wounding GO:1903034 189 0.031
nucleoside catabolic process GO:0009164 206 0.031
developmental maturation GO:0021700 193 0.030
regulation of cell adhesion GO:0030155 154 0.030
response to growth factor GO:0070848 198 0.030
camera type eye development GO:0043010 266 0.030
cell adhesion GO:0007155 329 0.030
regulation of cellular amine metabolic process GO:0033238 20 0.030
organonitrogen compound catabolic process GO:1901565 264 0.029
negative regulation of phosphorus metabolic process GO:0010563 184 0.029
organonitrogen compound biosynthetic process GO:1901566 192 0.029
cellular response to organonitrogen compound GO:0071417 145 0.029
positive regulation of apoptotic process GO:0043065 217 0.028
inflammatory response GO:0006954 244 0.028
neuronal action potential GO:0019228 54 0.028
positive regulation of cell development GO:0010720 237 0.028
small gtpase mediated signal transduction GO:0007264 97 0.027
negative regulation of phosphorylation GO:0042326 166 0.027
regulation of protein localization GO:0032880 231 0.027
regulation of hydrolase activity GO:0051336 246 0.027
cellular amine metabolic process GO:0044106 44 0.026
anion transport GO:0006820 177 0.026
immune effector process GO:0002252 321 0.025
metal ion homeostasis GO:0055065 189 0.025
regulation of defense response GO:0031347 233 0.025
positive regulation of cell projection organization GO:0031346 95 0.025
regulation of secretion GO:0051046 274 0.025
cellular nitrogen compound catabolic process GO:0044270 280 0.024
myelination GO:0042552 74 0.024
regulation of cytoskeleton organization GO:0051493 122 0.024
cellular homeostasis GO:0019725 240 0.023
negative regulation of cell development GO:0010721 169 0.023
regulation of cell projection organization GO:0031344 206 0.023
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.023
regulation of secretion by cell GO:1903530 249 0.023
positive regulation of neuron projection development GO:0010976 79 0.023
regulation of protein maturation GO:1903317 96 0.023
organophosphate catabolic process GO:0046434 232 0.022
ribonucleoside metabolic process GO:0009119 245 0.022
regulation of membrane potential GO:0042391 192 0.022
cellular response to transforming growth factor beta stimulus GO:0071560 88 0.021
i kappab kinase nf kappab signaling GO:0007249 85 0.021
cell growth GO:0016049 130 0.021
negative regulation of camp mediated signaling GO:0043951 3 0.021
carbohydrate derivative catabolic process GO:1901136 231 0.021
circulatory system process GO:0003013 197 0.021
positive regulation of neuron differentiation GO:0045666 141 0.021
heart morphogenesis GO:0003007 178 0.021
regulation of cell growth GO:0001558 91 0.020
transforming growth factor beta receptor signaling pathway GO:0007179 71 0.020
actin cytoskeleton organization GO:0030036 220 0.020
ossification GO:0001503 216 0.020
negative regulation of hydrolase activity GO:0051346 71 0.020
protein modification by small protein conjugation or removal GO:0070647 207 0.020
purine ribonucleotide catabolic process GO:0009154 208 0.019
purine ribonucleotide metabolic process GO:0009150 290 0.019
regulation of kinase activity GO:0043549 249 0.019
blood circulation GO:0008015 195 0.019
establishment of organelle localization GO:0051656 122 0.019
negative regulation of immune effector process GO:0002698 55 0.019
purine nucleotide metabolic process GO:0006163 302 0.019
cation homeostasis GO:0055080 212 0.019
response to extracellular stimulus GO:0009991 127 0.019
response to peptide hormone GO:0043434 127 0.019
defense response to other organism GO:0098542 197 0.019
regulation of apoptotic signaling pathway GO:2001233 197 0.019
negative regulation of protein maturation GO:1903318 79 0.019
regulation of cell activation GO:0050865 289 0.019
negative regulation of nik nf kappab signaling GO:1901223 2 0.019
anatomical structure maturation GO:0071695 49 0.019
negative regulation of protein processing GO:0010955 79 0.018
ribose phosphate metabolic process GO:0019693 291 0.018
skeletal system development GO:0001501 356 0.018
organelle localization GO:0051640 179 0.018
carboxylic acid transport GO:0046942 100 0.018
telencephalon development GO:0021537 186 0.018
peptidyl amino acid modification GO:0018193 336 0.018
negative regulation of intracellular signal transduction GO:1902532 167 0.018
nucleoside phosphate catabolic process GO:1901292 222 0.018
regulation of binding GO:0051098 111 0.018
cellular ion homeostasis GO:0006873 165 0.018
regulation of cellular catabolic process GO:0031329 242 0.018
protein catabolic process GO:0030163 221 0.018
negative regulation of protein modification process GO:0031400 163 0.018
stem cell development GO:0048864 219 0.018
multicellular organismal signaling GO:0035637 91 0.017
cytokine production GO:0001816 319 0.017
negative regulation of cellular component organization GO:0051129 194 0.017
aromatic compound catabolic process GO:0019439 286 0.017
glycosyl compound metabolic process GO:1901657 246 0.017
cellular lipid metabolic process GO:0044255 323 0.017
negative regulation of immune system process GO:0002683 209 0.017
negative regulation of transferase activity GO:0051348 85 0.017
axon ensheathment GO:0008366 76 0.017
gland development GO:0048732 330 0.016
cellular macromolecule catabolic process GO:0044265 206 0.016
negative regulation of phosphate metabolic process GO:0045936 184 0.016
organic hydroxy compound transport GO:0015850 93 0.016
ribonucleotide metabolic process GO:0009259 291 0.016
organic acid transport GO:0015849 101 0.016
multi multicellular organism process GO:0044706 109 0.016
negative regulation of cell activation GO:0050866 111 0.016
protein modification by small protein conjugation GO:0032446 187 0.016
organic anion transport GO:0015711 137 0.016
regulation of protein binding GO:0043393 60 0.016
response to acid chemical GO:0001101 111 0.016
ribonucleoside catabolic process GO:0042454 206 0.016
lipid biosynthetic process GO:0008610 179 0.015
sterol homeostasis GO:0055092 45 0.015
regulation of purine nucleotide metabolic process GO:1900542 169 0.015
positive regulation of hydrolase activity GO:0051345 148 0.015
cell type specific apoptotic process GO:0097285 268 0.015
fat cell differentiation GO:0045444 160 0.015
cytoplasmic transport GO:0016482 234 0.015
regulation of neurotransmitter levels GO:0001505 87 0.015
ribonucleoside triphosphate catabolic process GO:0009203 199 0.015
nucleoside triphosphate metabolic process GO:0009141 230 0.015
positive regulation of secretion GO:0051047 130 0.015
muscle tissue development GO:0060537 308 0.015
nucleoside triphosphate catabolic process GO:0009143 205 0.015
regulation of establishment of protein localization GO:0070201 181 0.015
carbohydrate homeostasis GO:0033500 128 0.015
regulation of ion transport GO:0043269 215 0.015
positive regulation of defense response GO:0031349 124 0.015
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.015
regulation of neuron differentiation GO:0045664 281 0.015
divalent inorganic cation homeostasis GO:0072507 138 0.014
cellular component assembly involved in morphogenesis GO:0010927 139 0.014
neuron neuron synaptic transmission GO:0007270 69 0.014
pallium development GO:0021543 120 0.014
negative regulation of phospholipase activity GO:0010519 4 0.014
purine nucleotide catabolic process GO:0006195 211 0.014
regulation of proteolysis GO:0030162 164 0.014
gliogenesis GO:0042063 141 0.014
nucleoside phosphate metabolic process GO:0006753 338 0.014
retina development in camera type eye GO:0060041 119 0.014
cellular response to lipid GO:0071396 145 0.014
wnt signaling pathway GO:0016055 188 0.014
response to organonitrogen compound GO:0010243 246 0.014
response to lipopolysaccharide GO:0032496 128 0.014
negative regulation of cell proliferation GO:0008285 296 0.014
response to peptide GO:1901652 136 0.013
meiotic nuclear division GO:0007126 115 0.013
cellular response to insulin stimulus GO:0032869 78 0.013
small molecule biosynthetic process GO:0044283 132 0.013
regulation of organelle organization GO:0033043 289 0.013
carboxylic acid biosynthetic process GO:0046394 86 0.013
peptidyl tyrosine modification GO:0018212 145 0.013
regulation of cellular component biogenesis GO:0044087 181 0.013
learning or memory GO:0007611 148 0.013
regulation of canonical wnt signaling pathway GO:0060828 82 0.013
neurotransmitter transport GO:0006836 76 0.013
positive regulation of protein modification process GO:0031401 299 0.013
heterocycle catabolic process GO:0046700 280 0.013
regulation of multi organism process GO:0043900 111 0.013
regulation of protein processing GO:0070613 96 0.013
chromatin organization GO:0006325 206 0.013
proteoglycan metabolic process GO:0006029 38 0.013
meiotic cell cycle GO:0051321 122 0.013
defense response to virus GO:0051607 68 0.013
peptide hormone secretion GO:0030072 109 0.013
l amino acid transport GO:0015807 32 0.013
chemotaxis GO:0006935 247 0.012
regulation of transferase activity GO:0051338 263 0.012
regulation of homeostatic process GO:0032844 182 0.012
cardiac ventricle morphogenesis GO:0003208 50 0.012
nucleoside metabolic process GO:0009116 246 0.012
regulation of myeloid cell differentiation GO:0045637 96 0.012
glucose homeostasis GO:0042593 128 0.012
negative regulation of apoptotic signaling pathway GO:2001234 104 0.012
carbohydrate transport GO:0008643 62 0.012
calcium ion homeostasis GO:0055074 127 0.012
sensory perception GO:0007600 245 0.012
ion transmembrane transport GO:0034220 361 0.012
purine containing compound metabolic process GO:0072521 311 0.012
organic cyclic compound catabolic process GO:1901361 295 0.012
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.012
astrocyte differentiation GO:0048708 43 0.012
chondrocyte differentiation GO:0002062 72 0.012
establishment of tissue polarity GO:0007164 28 0.012
membrane organization GO:0061024 245 0.012
positive regulation of secretion by cell GO:1903532 114 0.012
purine nucleoside metabolic process GO:0042278 241 0.012
positive regulation of nervous system development GO:0051962 221 0.012
cellular calcium ion homeostasis GO:0006874 119 0.012
purine nucleoside triphosphate metabolic process GO:0009144 226 0.012
sequestering of calcium ion GO:0051208 18 0.012
negative regulation of proteolysis GO:0045861 74 0.012
cartilage development GO:0051216 140 0.012
regulation of phosphatidylcholine biosynthetic process GO:2001245 2 0.012
carbohydrate metabolic process GO:0005975 230 0.012
organic acid biosynthetic process GO:0016053 86 0.012
skeletal system morphogenesis GO:0048705 203 0.012
peptidyl serine modification GO:0018209 83 0.012
carbohydrate derivative biosynthetic process GO:1901137 183 0.012
leukocyte proliferation GO:0070661 172 0.012
positive regulation of cellular catabolic process GO:0031331 148 0.012
regulation of wnt signaling pathway GO:0030111 123 0.011
maintenance of location GO:0051235 89 0.011
cognition GO:0050890 149 0.011
sulfur compound metabolic process GO:0006790 100 0.011
blood vessel morphogenesis GO:0048514 285 0.011
organelle assembly GO:0070925 177 0.011
cellular metal ion homeostasis GO:0006875 151 0.011
defense response to bacterium GO:0042742 119 0.011
response to insulin GO:0032868 100 0.011
regulation of anatomical structure size GO:0090066 178 0.011
ribonucleotide catabolic process GO:0009261 208 0.011
regulation of body fluid levels GO:0050878 162 0.011
regulation of lymphocyte activation GO:0051249 240 0.011
regulation of neuron projection development GO:0010975 169 0.011
g protein coupled receptor signaling pathway GO:0007186 243 0.011
lateral inhibition GO:0046331 1 0.011
neuron migration GO:0001764 122 0.011
metaphase plate congression GO:0051310 2 0.011
epithelial cell proliferation GO:0050673 174 0.011
regulation of organ morphogenesis GO:2000027 144 0.011
cellular response to peptide GO:1901653 92 0.011
lipid localization GO:0010876 126 0.011
regulation of map kinase activity GO:0043405 120 0.011
glycosyl compound catabolic process GO:1901658 206 0.011
posttranscriptional regulation of gene expression GO:0010608 155 0.011
spermatogenesis GO:0007283 284 0.011
response to molecule of bacterial origin GO:0002237 143 0.011
protein secretion GO:0009306 111 0.011
heart process GO:0003015 94 0.011
peptide secretion GO:0002790 114 0.011
odontogenesis GO:0042476 78 0.010
nucleotide catabolic process GO:0009166 217 0.010
regulation of cell migration GO:0030334 219 0.010
monosaccharide transport GO:0015749 58 0.010
sulfur compound biosynthetic process GO:0044272 37 0.010
negative regulation of kinase activity GO:0033673 81 0.010
hexose transport GO:0008645 56 0.010
brown fat cell differentiation GO:0050873 36 0.010
regulation of protein serine threonine kinase activity GO:0071900 157 0.010
positive regulation of protein phosphorylation GO:0001934 242 0.010
regulation of inflammatory response GO:0050727 147 0.010
positive regulation of growth GO:0045927 104 0.010
regulation of tooth mineralization GO:0070170 2 0.010
cellular response to dna damage stimulus GO:0006974 207 0.010
positive regulation of protein export from nucleus GO:0046827 4 0.010
regulation of nucleotide metabolic process GO:0006140 169 0.010
regulation of cell size GO:0008361 72 0.010

Itm2a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
muscle tissue disease DOID:66 0 0.024
myopathy DOID:423 0 0.024
muscular disease DOID:0080000 0 0.024
disease of anatomical entity DOID:7 0 0.024
musculoskeletal system disease DOID:17 0 0.024
nervous system disease DOID:863 0 0.023
connective tissue disease DOID:65 0 0.011