Mus musculus

0 known processes

Itm2a

integral membrane protein 2A

(Aliases: AW108051,Itm2,E25)

Itm2a biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular response to growth factor stimulus GO:0071363 197 0.090
negative regulation of molecular function GO:0044092 258 0.088
amine metabolic process GO:0009308 45 0.085
negative regulation of protein metabolic process GO:0051248 282 0.076
protein processing GO:0016485 163 0.066
extracellular structure organization GO:0043062 148 0.066
nitrogen compound transport GO:0071705 271 0.056
response to transforming growth factor beta GO:0071559 88 0.053
cellular amino acid metabolic process GO:0006520 103 0.052
synaptic transmission GO:0007268 329 0.046
regulation of cellular ketone metabolic process GO:0010565 66 0.044
regulation of cellular amino acid metabolic process GO:0006521 5 0.043
protein maturation GO:0051604 176 0.043
cellular ketone metabolic process GO:0042180 84 0.041
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.039
positive regulation of cell death GO:0010942 224 0.039
monocarboxylic acid metabolic process GO:0032787 191 0.038
action potential GO:0001508 78 0.038
extracellular matrix organization GO:0030198 147 0.037
negative regulation of cellular protein metabolic process GO:0032269 247 0.037
positive regulation of cellular amine metabolic process GO:0033240 5 0.037
macromolecule catabolic process GO:0009057 281 0.037
transmembrane transport GO:0055085 412 0.036
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.035
glycoprotein metabolic process GO:0009100 116 0.035
ras protein signal transduction GO:0007265 77 0.034
response to organic cyclic compound GO:0014070 198 0.034
cation transport GO:0006812 399 0.033
multicellular organism growth GO:0035264 161 0.033
mitochondrion organization GO:0007005 134 0.033
cellular response to hormone stimulus GO:0032870 150 0.033
positive regulation of programmed cell death GO:0043068 218 0.032
transmission of nerve impulse GO:0019226 76 0.032
cellular chemical homeostasis GO:0055082 215 0.031
dna metabolic process GO:0006259 303 0.031
neural tube development GO:0021915 160 0.031
regulation of response to wounding GO:1903034 189 0.031
nucleoside catabolic process GO:0009164 206 0.031
developmental maturation GO:0021700 193 0.030
regulation of cell adhesion GO:0030155 154 0.030
response to growth factor GO:0070848 198 0.030
camera type eye development GO:0043010 266 0.030
cell adhesion GO:0007155 329 0.030
regulation of cellular amine metabolic process GO:0033238 20 0.030
organonitrogen compound catabolic process GO:1901565 264 0.029
negative regulation of phosphorus metabolic process GO:0010563 184 0.029
organonitrogen compound biosynthetic process GO:1901566 192 0.029
cellular response to organonitrogen compound GO:0071417 145 0.029
positive regulation of apoptotic process GO:0043065 217 0.028
inflammatory response GO:0006954 244 0.028
neuronal action potential GO:0019228 54 0.028
positive regulation of cell development GO:0010720 237 0.028
small gtpase mediated signal transduction GO:0007264 97 0.027
negative regulation of phosphorylation GO:0042326 166 0.027
regulation of protein localization GO:0032880 231 0.027
regulation of hydrolase activity GO:0051336 246 0.027
cellular amine metabolic process GO:0044106 44 0.026
anion transport GO:0006820 177 0.026
immune effector process GO:0002252 321 0.025
metal ion homeostasis GO:0055065 189 0.025
regulation of defense response GO:0031347 233 0.025
positive regulation of cell projection organization GO:0031346 95 0.025
regulation of secretion GO:0051046 274 0.025
cellular nitrogen compound catabolic process GO:0044270 280 0.024
myelination GO:0042552 74 0.024
regulation of cytoskeleton organization GO:0051493 122 0.024
cellular homeostasis GO:0019725 240 0.023
negative regulation of cell development GO:0010721 169 0.023
regulation of cell projection organization GO:0031344 206 0.023
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.023
regulation of secretion by cell GO:1903530 249 0.023
positive regulation of neuron projection development GO:0010976 79 0.023
regulation of protein maturation GO:1903317 96 0.023
organophosphate catabolic process GO:0046434 232 0.022
ribonucleoside metabolic process GO:0009119 245 0.022
regulation of membrane potential GO:0042391 192 0.022
cellular response to transforming growth factor beta stimulus GO:0071560 88 0.021
i kappab kinase nf kappab signaling GO:0007249 85 0.021
cell growth GO:0016049 130 0.021
negative regulation of camp mediated signaling GO:0043951 3 0.021
carbohydrate derivative catabolic process GO:1901136 231 0.021
circulatory system process GO:0003013 197 0.021
positive regulation of neuron differentiation GO:0045666 141 0.021
heart morphogenesis GO:0003007 178 0.021
regulation of cell growth GO:0001558 91 0.020
transforming growth factor beta receptor signaling pathway GO:0007179 71 0.020
actin cytoskeleton organization GO:0030036 220 0.020
ossification GO:0001503 216 0.020
negative regulation of hydrolase activity GO:0051346 71 0.020
protein modification by small protein conjugation or removal GO:0070647 207 0.020
purine ribonucleotide catabolic process GO:0009154 208 0.019
purine ribonucleotide metabolic process GO:0009150 290 0.019
regulation of kinase activity GO:0043549 249 0.019
blood circulation GO:0008015 195 0.019
establishment of organelle localization GO:0051656 122 0.019
negative regulation of immune effector process GO:0002698 55 0.019
purine nucleotide metabolic process GO:0006163 302 0.019
cation homeostasis GO:0055080 212 0.019
response to extracellular stimulus GO:0009991 127 0.019
response to peptide hormone GO:0043434 127 0.019
defense response to other organism GO:0098542 197 0.019
regulation of apoptotic signaling pathway GO:2001233 197 0.019
negative regulation of protein maturation GO:1903318 79 0.019
regulation of cell activation GO:0050865 289 0.019
negative regulation of nik nf kappab signaling GO:1901223 2 0.019
anatomical structure maturation GO:0071695 49 0.019
negative regulation of protein processing GO:0010955 79 0.018
ribose phosphate metabolic process GO:0019693 291 0.018
skeletal system development GO:0001501 356 0.018
organelle localization GO:0051640 179 0.018
carboxylic acid transport GO:0046942 100 0.018
telencephalon development GO:0021537 186 0.018
peptidyl amino acid modification GO:0018193 336 0.018
negative regulation of intracellular signal transduction GO:1902532 167 0.018
nucleoside phosphate catabolic process GO:1901292 222 0.018
regulation of binding GO:0051098 111 0.018
cellular ion homeostasis GO:0006873 165 0.018
regulation of cellular catabolic process GO:0031329 242 0.018
protein catabolic process GO:0030163 221 0.018
negative regulation of protein modification process GO:0031400 163 0.018
stem cell development GO:0048864 219 0.018
multicellular organismal signaling GO:0035637 91 0.017
cytokine production GO:0001816 319 0.017
negative regulation of cellular component organization GO:0051129 194 0.017
aromatic compound catabolic process GO:0019439 286 0.017
glycosyl compound metabolic process GO:1901657 246 0.017
cellular lipid metabolic process GO:0044255 323 0.017
negative regulation of immune system process GO:0002683 209 0.017
negative regulation of transferase activity GO:0051348 85 0.017
axon ensheathment GO:0008366 76 0.017
gland development GO:0048732 330 0.016
cellular macromolecule catabolic process GO:0044265 206 0.016
negative regulation of phosphate metabolic process GO:0045936 184 0.016
organic hydroxy compound transport GO:0015850 93 0.016
ribonucleotide metabolic process GO:0009259 291 0.016
organic acid transport GO:0015849 101 0.016
multi multicellular organism process GO:0044706 109 0.016
negative regulation of cell activation GO:0050866 111 0.016
protein modification by small protein conjugation GO:0032446 187 0.016
organic anion transport GO:0015711 137 0.016
regulation of protein binding GO:0043393 60 0.016
response to acid chemical GO:0001101 111 0.016
ribonucleoside catabolic process GO:0042454 206 0.016
lipid biosynthetic process GO:0008610 179 0.015
sterol homeostasis GO:0055092 45 0.015
regulation of purine nucleotide metabolic process GO:1900542 169 0.015
positive regulation of hydrolase activity GO:0051345 148 0.015
cell type specific apoptotic process GO:0097285 268 0.015
fat cell differentiation GO:0045444 160 0.015
cytoplasmic transport GO:0016482 234 0.015
regulation of neurotransmitter levels GO:0001505 87 0.015
ribonucleoside triphosphate catabolic process GO:0009203 199 0.015
nucleoside triphosphate metabolic process GO:0009141 230 0.015
positive regulation of secretion GO:0051047 130 0.015
muscle tissue development GO:0060537 308 0.015
nucleoside triphosphate catabolic process GO:0009143 205 0.015
regulation of establishment of protein localization GO:0070201 181 0.015
carbohydrate homeostasis GO:0033500 128 0.015
regulation of ion transport GO:0043269 215 0.015
positive regulation of defense response GO:0031349 124 0.015
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.015
regulation of neuron differentiation GO:0045664 281 0.015
divalent inorganic cation homeostasis GO:0072507 138 0.014
cellular component assembly involved in morphogenesis GO:0010927 139 0.014
neuron neuron synaptic transmission GO:0007270 69 0.014
pallium development GO:0021543 120 0.014
negative regulation of phospholipase activity GO:0010519 4 0.014
purine nucleotide catabolic process GO:0006195 211 0.014
regulation of proteolysis GO:0030162 164 0.014
gliogenesis GO:0042063 141 0.014
nucleoside phosphate metabolic process GO:0006753 338 0.014
retina development in camera type eye GO:0060041 119 0.014
cellular response to lipid GO:0071396 145 0.014
wnt signaling pathway GO:0016055 188 0.014
response to organonitrogen compound GO:0010243 246 0.014
response to lipopolysaccharide GO:0032496 128 0.014
negative regulation of cell proliferation GO:0008285 296 0.014
response to peptide GO:1901652 136 0.013
meiotic nuclear division GO:0007126 115 0.013
cellular response to insulin stimulus GO:0032869 78 0.013
small molecule biosynthetic process GO:0044283 132 0.013
regulation of organelle organization GO:0033043 289 0.013
carboxylic acid biosynthetic process GO:0046394 86 0.013
peptidyl tyrosine modification GO:0018212 145 0.013
regulation of cellular component biogenesis GO:0044087 181 0.013
learning or memory GO:0007611 148 0.013
regulation of canonical wnt signaling pathway GO:0060828 82 0.013
neurotransmitter transport GO:0006836 76 0.013
positive regulation of protein modification process GO:0031401 299 0.013
heterocycle catabolic process GO:0046700 280 0.013
regulation of multi organism process GO:0043900 111 0.013
regulation of protein processing GO:0070613 96 0.013
chromatin organization GO:0006325 206 0.013
proteoglycan metabolic process GO:0006029 38 0.013
meiotic cell cycle GO:0051321 122 0.013
defense response to virus GO:0051607 68 0.013
peptide hormone secretion GO:0030072 109 0.013
l amino acid transport GO:0015807 32 0.013
chemotaxis GO:0006935 247 0.012
regulation of transferase activity GO:0051338 263 0.012
regulation of homeostatic process GO:0032844 182 0.012
cardiac ventricle morphogenesis GO:0003208 50 0.012
nucleoside metabolic process GO:0009116 246 0.012
regulation of myeloid cell differentiation GO:0045637 96 0.012
glucose homeostasis GO:0042593 128 0.012
negative regulation of apoptotic signaling pathway GO:2001234 104 0.012
carbohydrate transport GO:0008643 62 0.012
calcium ion homeostasis GO:0055074 127 0.012
sensory perception GO:0007600 245 0.012
ion transmembrane transport GO:0034220 361 0.012
purine containing compound metabolic process GO:0072521 311 0.012
organic cyclic compound catabolic process GO:1901361 295 0.012
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.012
astrocyte differentiation GO:0048708 43 0.012
chondrocyte differentiation GO:0002062 72 0.012
establishment of tissue polarity GO:0007164 28 0.012
membrane organization GO:0061024 245 0.012
positive regulation of secretion by cell GO:1903532 114 0.012
purine nucleoside metabolic process GO:0042278 241 0.012
positive regulation of nervous system development GO:0051962 221 0.012
cellular calcium ion homeostasis GO:0006874 119 0.012
purine nucleoside triphosphate metabolic process GO:0009144 226 0.012
sequestering of calcium ion GO:0051208 18 0.012
negative regulation of proteolysis GO:0045861 74 0.012
cartilage development GO:0051216 140 0.012
regulation of phosphatidylcholine biosynthetic process GO:2001245 2 0.012
carbohydrate metabolic process GO:0005975 230 0.012
organic acid biosynthetic process GO:0016053 86 0.012
skeletal system morphogenesis GO:0048705 203 0.012
peptidyl serine modification GO:0018209 83 0.012
carbohydrate derivative biosynthetic process GO:1901137 183 0.012
leukocyte proliferation GO:0070661 172 0.012
positive regulation of cellular catabolic process GO:0031331 148 0.012
regulation of wnt signaling pathway GO:0030111 123 0.011
maintenance of location GO:0051235 89 0.011
cognition GO:0050890 149 0.011
sulfur compound metabolic process GO:0006790 100 0.011
blood vessel morphogenesis GO:0048514 285 0.011
organelle assembly GO:0070925 177 0.011
cellular metal ion homeostasis GO:0006875 151 0.011
defense response to bacterium GO:0042742 119 0.011
response to insulin GO:0032868 100 0.011
regulation of anatomical structure size GO:0090066 178 0.011
ribonucleotide catabolic process GO:0009261 208 0.011
regulation of body fluid levels GO:0050878 162 0.011
regulation of lymphocyte activation GO:0051249 240 0.011
regulation of neuron projection development GO:0010975 169 0.011
g protein coupled receptor signaling pathway GO:0007186 243 0.011
lateral inhibition GO:0046331 1 0.011
neuron migration GO:0001764 122 0.011
metaphase plate congression GO:0051310 2 0.011
epithelial cell proliferation GO:0050673 174 0.011
regulation of organ morphogenesis GO:2000027 144 0.011
cellular response to peptide GO:1901653 92 0.011
lipid localization GO:0010876 126 0.011
regulation of map kinase activity GO:0043405 120 0.011
glycosyl compound catabolic process GO:1901658 206 0.011
posttranscriptional regulation of gene expression GO:0010608 155 0.011
spermatogenesis GO:0007283 284 0.011
response to molecule of bacterial origin GO:0002237 143 0.011
protein secretion GO:0009306 111 0.011
heart process GO:0003015 94 0.011
peptide secretion GO:0002790 114 0.011
odontogenesis GO:0042476 78 0.010
nucleotide catabolic process GO:0009166 217 0.010
regulation of cell migration GO:0030334 219 0.010
monosaccharide transport GO:0015749 58 0.010
sulfur compound biosynthetic process GO:0044272 37 0.010
negative regulation of kinase activity GO:0033673 81 0.010
hexose transport GO:0008645 56 0.010
brown fat cell differentiation GO:0050873 36 0.010
regulation of protein serine threonine kinase activity GO:0071900 157 0.010
positive regulation of protein phosphorylation GO:0001934 242 0.010
regulation of inflammatory response GO:0050727 147 0.010
positive regulation of growth GO:0045927 104 0.010
regulation of tooth mineralization GO:0070170 2 0.010
cellular response to dna damage stimulus GO:0006974 207 0.010
positive regulation of protein export from nucleus GO:0046827 4 0.010
regulation of nucleotide metabolic process GO:0006140 169 0.010
regulation of cell size GO:0008361 72 0.010

Itm2a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
myopathy DOID:423 0 0.024
muscular disease DOID:0080000 0 0.024
disease of anatomical entity DOID:7 0 0.024
musculoskeletal system disease DOID:17 0 0.024
muscle tissue disease DOID:66 0 0.024
nervous system disease DOID:863 0 0.023
connective tissue disease DOID:65 0 0.011