Mus musculus

0 known processes

Klhl28

kelch-like 28 (Drosophila)

(Aliases: Btbd5,MGC47075,4931401E10Rik,2810440N09Rik,4122402F11Rik)

Klhl28 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of cellular ketone metabolic process GO:0010565 66 0.054
positive regulation of cellular amine metabolic process GO:0033240 5 0.049
modification dependent protein catabolic process GO:0019941 133 0.049
small gtpase mediated signal transduction GO:0007264 97 0.047
ras protein signal transduction GO:0007265 77 0.047
cellular amino acid metabolic process GO:0006520 103 0.044
protein modification by small protein conjugation or removal GO:0070647 207 0.044
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.040
carbohydrate metabolic process GO:0005975 230 0.039
covalent chromatin modification GO:0016569 163 0.037
cellular macromolecule catabolic process GO:0044265 206 0.036
male gamete generation GO:0048232 285 0.035
Mouse
protein modification by small protein conjugation GO:0032446 187 0.035
spermatogenesis GO:0007283 284 0.035
Mouse
methylation GO:0032259 134 0.032
regulation of cellular amine metabolic process GO:0033238 20 0.032
cellular ketone metabolic process GO:0042180 84 0.032
macromolecule catabolic process GO:0009057 281 0.031
regulation of cellular amino acid metabolic process GO:0006521 5 0.030
purine ribonucleotide metabolic process GO:0009150 290 0.030
heart morphogenesis GO:0003007 178 0.028
protein ubiquitination GO:0016567 171 0.028
forebrain development GO:0030900 302 0.028
cellular homeostasis GO:0019725 240 0.028
homeostasis of number of cells GO:0048872 210 0.028
Mouse
cellular protein catabolic process GO:0044257 155 0.027
regulation of cell motility GO:2000145 236 0.027
epithelial cell development GO:0002064 159 0.027
dna metabolic process GO:0006259 303 0.027
camera type eye development GO:0043010 266 0.027
ubiquitin dependent protein catabolic process GO:0006511 129 0.026
modification dependent macromolecule catabolic process GO:0043632 133 0.026
amine metabolic process GO:0009308 45 0.026
myeloid cell differentiation GO:0030099 233 0.025
aromatic compound catabolic process GO:0019439 286 0.025
cellular amine metabolic process GO:0044106 44 0.025
immune effector process GO:0002252 321 0.025
rho protein signal transduction GO:0007266 32 0.025
histone modification GO:0016570 159 0.024
peptidyl amino acid modification GO:0018193 336 0.024
nucleoside metabolic process GO:0009116 246 0.024
chromatin modification GO:0016568 187 0.023
microtubule based process GO:0007017 236 0.023
positive regulation of protein modification process GO:0031401 299 0.023
regulation of nucleotide metabolic process GO:0006140 169 0.023
cellular response to dna damage stimulus GO:0006974 207 0.022
cellular nitrogen compound catabolic process GO:0044270 280 0.022
ribose phosphate metabolic process GO:0019693 291 0.022
negative regulation of cellular component organization GO:0051129 194 0.022
oxidation reduction process GO:0055114 342 0.022
protein catabolic process GO:0030163 221 0.022
nucleoside phosphate metabolic process GO:0006753 338 0.022
transmembrane transport GO:0055085 412 0.022
organelle localization GO:0051640 179 0.022
sensory organ morphogenesis GO:0090596 242 0.021
cation transport GO:0006812 399 0.021
muscle system process GO:0003012 141 0.021
gland development GO:0048732 330 0.021
microtubule cytoskeleton organization GO:0000226 157 0.021
macromolecule methylation GO:0043414 120 0.021
organonitrogen compound catabolic process GO:1901565 264 0.021
response to acid chemical GO:0001101 111 0.021
dephosphorylation GO:0016311 129 0.021
cell type specific apoptotic process GO:0097285 268 0.021
response to organic cyclic compound GO:0014070 198 0.021
mapk cascade GO:0000165 281 0.020
negative regulation of molecular function GO:0044092 258 0.020
purine nucleotide metabolic process GO:0006163 302 0.020
cytoplasmic transport GO:0016482 234 0.020
heterocycle catabolic process GO:0046700 280 0.020
regulation of cell migration GO:0030334 219 0.019
negative regulation of protein metabolic process GO:0051248 282 0.019
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.019
regulation of organelle organization GO:0033043 289 0.019
negative regulation of cellular protein metabolic process GO:0032269 247 0.019
nucleotide metabolic process GO:0009117 332 0.019
regulation of cell projection organization GO:0031344 206 0.019
regulation of transferase activity GO:0051338 263 0.019
lateral line system development GO:0048925 1 0.018
metal ion homeostasis GO:0055065 189 0.018
organic cyclic compound catabolic process GO:1901361 295 0.018
regulation of body fluid levels GO:0050878 162 0.018
leukocyte differentiation GO:0002521 342 0.018
purine ribonucleotide catabolic process GO:0009154 208 0.018
regulation of hydrolase activity GO:0051336 246 0.018
endomembrane system organization GO:0010256 147 0.018
purine nucleotide catabolic process GO:0006195 211 0.017
ribonucleoside triphosphate metabolic process GO:0009199 220 0.017
cellular chemical homeostasis GO:0055082 215 0.017
angiogenesis GO:0001525 201 0.017
positive regulation of mapk cascade GO:0043410 170 0.017
nucleoside triphosphate metabolic process GO:0009141 230 0.017
wound healing GO:0042060 157 0.017
organelle fission GO:0048285 170 0.017
regulation of apoptotic signaling pathway GO:2001233 197 0.017
Mouse
response to radiation GO:0009314 165 0.017
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.017
regulation of cellular response to stress GO:0080135 159 0.017
cellular response to hormone stimulus GO:0032870 150 0.017
regulation of anatomical structure size GO:0090066 178 0.017
purine containing compound metabolic process GO:0072521 311 0.017
regulation of cell adhesion GO:0030155 154 0.017
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.017
response to growth factor GO:0070848 198 0.017
nucleoside triphosphate catabolic process GO:0009143 205 0.016
nucleoside phosphate catabolic process GO:1901292 222 0.016
divalent inorganic cation transport GO:0072511 178 0.016
purine nucleoside metabolic process GO:0042278 241 0.016
cation homeostasis GO:0055080 212 0.016
germ cell development GO:0007281 185 0.016
Mouse
maintenance of location GO:0051235 89 0.016
purine nucleoside triphosphate metabolic process GO:0009144 226 0.016
carbohydrate derivative biosynthetic process GO:1901137 183 0.016
ribonucleoside metabolic process GO:0009119 245 0.016
divalent inorganic cation homeostasis GO:0072507 138 0.016
glycosyl compound metabolic process GO:1901657 246 0.016
actin filament organization GO:0007015 113 0.016
hematopoietic progenitor cell differentiation GO:0002244 143 0.016
g protein coupled receptor signaling pathway GO:0007186 243 0.016
locomotory behavior GO:0007626 195 0.016
Mouse
negative regulation of phosphorylation GO:0042326 166 0.016
ribonucleotide metabolic process GO:0009259 291 0.016
establishment or maintenance of cytoskeleton polarity GO:0030952 2 0.016
nucleotide catabolic process GO:0009166 217 0.016
actin cytoskeleton organization GO:0030036 220 0.016
regulation of ion transport GO:0043269 215 0.016
negative regulation of intracellular signal transduction GO:1902532 167 0.016
Mouse
epithelial tube morphogenesis GO:0060562 303 0.015
renal system development GO:0072001 225 0.015
calcium ion homeostasis GO:0055074 127 0.015
endocytosis GO:0006897 168 0.015
developmental maturation GO:0021700 193 0.015
nucleobase containing small molecule metabolic process GO:0055086 352 0.015
nuclear division GO:0000280 158 0.015
synaptic transmission GO:0007268 329 0.015
cellular response to organonitrogen compound GO:0071417 145 0.015
organonitrogen compound biosynthetic process GO:1901566 192 0.015
chromatin organization GO:0006325 206 0.015
apoptotic signaling pathway GO:0097190 306 0.015
Mouse
purine ribonucleoside metabolic process GO:0046128 241 0.015
sensory system development GO:0048880 3 0.015
nitrogen compound transport GO:0071705 271 0.015
ribonucleoside catabolic process GO:0042454 206 0.015
negative regulation of organelle organization GO:0010639 90 0.015
cellular ion homeostasis GO:0006873 165 0.015
positive regulation of nervous system development GO:0051962 221 0.015
developmental growth involved in morphogenesis GO:0060560 138 0.015
circulatory system process GO:0003013 197 0.015
regulation of cellular catabolic process GO:0031329 242 0.015
neuron death GO:0070997 154 0.015
regulation of ras protein signal transduction GO:0046578 114 0.015
guanosine containing compound catabolic process GO:1901069 144 0.014
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.014
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.014
divalent metal ion transport GO:0070838 172 0.014
ameboidal type cell migration GO:0001667 128 0.014
multicellular organism growth GO:0035264 161 0.014
regulation of lymphocyte activation GO:0051249 240 0.014
regulation of mapk cascade GO:0043408 248 0.014
cell substrate adhesion GO:0031589 130 0.014
dna modification GO:0006304 50 0.014
regulation of cellular component size GO:0032535 121 0.014
retrograde transport endosome to golgi GO:0042147 2 0.014
telencephalon development GO:0021537 186 0.014
cellular protein complex assembly GO:0043623 116 0.014
organophosphate catabolic process GO:0046434 232 0.014
regulation of cell activation GO:0050865 289 0.014
regulation of neuron differentiation GO:0045664 281 0.014
response to light stimulus GO:0009416 135 0.014
retina development in camera type eye GO:0060041 119 0.014
cellular lipid metabolic process GO:0044255 323 0.014
skeletal system development GO:0001501 356 0.014
negative regulation of apoptotic signaling pathway GO:2001234 104 0.013
Mouse
cellular calcium ion homeostasis GO:0006874 119 0.013
muscle tissue development GO:0060537 308 0.013
blood vessel morphogenesis GO:0048514 285 0.013
respiratory tube development GO:0030323 167 0.013
protein methylation GO:0006479 81 0.013
carbohydrate derivative catabolic process GO:1901136 231 0.013
apical constriction GO:0003383 4 0.013
gtp catabolic process GO:0006184 143 0.013
organic hydroxy compound metabolic process GO:1901615 203 0.013
cellular carbohydrate metabolic process GO:0044262 119 0.013
neural tube development GO:0021915 160 0.013
hepaticobiliary system development GO:0061008 67 0.013
ion transmembrane transport GO:0034220 361 0.013
mitotic cell cycle process GO:1903047 159 0.013
respiratory system development GO:0060541 190 0.013
embryonic organ morphogenesis GO:0048562 276 0.013
cell adhesion GO:0007155 329 0.013
cellular metal ion homeostasis GO:0006875 151 0.013
smoothened signaling pathway GO:0007224 105 0.013
purine nucleoside catabolic process GO:0006152 205 0.013
organophosphate biosynthetic process GO:0090407 122 0.013
regulation of purine nucleotide catabolic process GO:0033121 122 0.013
regulation of system process GO:0044057 200 0.013
muscle cell differentiation GO:0042692 261 0.013
meiotic cell cycle GO:0051321 122 0.013
regulation of vesicle mediated transport GO:0060627 139 0.013
fat cell differentiation GO:0045444 160 0.013
inorganic cation transmembrane transport GO:0098662 207 0.012
regulation of muscle system process GO:0090257 80 0.012
positive regulation of protein kinase activity GO:0045860 144 0.012
genetic imprinting GO:0071514 27 0.012
establishment of organelle localization GO:0051656 122 0.012
blood circulation GO:0008015 195 0.012
cyclic nucleotide metabolic process GO:0009187 59 0.012
regulation of protein kinase activity GO:0045859 232 0.012
sensory perception GO:0007600 245 0.012
regulation of metal ion transport GO:0010959 106 0.012
purine nucleoside triphosphate catabolic process GO:0009146 203 0.012
negative regulation of phosphorus metabolic process GO:0010563 184 0.012
regulation of establishment of protein localization GO:0070201 181 0.012
cation transmembrane transport GO:0098655 266 0.012
regulation of endocytosis GO:0030100 69 0.012
urogenital system development GO:0001655 261 0.012
striated muscle tissue development GO:0014706 293 0.012
negative regulation of immune system process GO:0002683 209 0.012
leukocyte mediated immunity GO:0002443 174 0.012
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.012
skeletal muscle organ development GO:0060538 163 0.012
protein processing GO:0016485 163 0.012
protein maturation GO:0051604 176 0.012
purine containing compound catabolic process GO:0072523 213 0.012
cellular response to organic cyclic compound GO:0071407 87 0.012
negative regulation of cell development GO:0010721 169 0.012
protein glycosylation GO:0006486 55 0.012
membrane organization GO:0061024 245 0.012
positive regulation of cellular catabolic process GO:0031331 148 0.012
regulation of chromatin modification GO:1903308 57 0.012
negative regulation of phosphate metabolic process GO:0045936 184 0.012
regulation of kinase activity GO:0043549 249 0.012
negative regulation of protein modification process GO:0031400 163 0.012
negative regulation of lymphocyte activation GO:0051250 91 0.012
transforming growth factor beta receptor signaling pathway GO:0007179 71 0.012
synaptic vesicle transport GO:0048489 57 0.012
lung development GO:0030324 164 0.012
glycosylation GO:0070085 62 0.012
ossification GO:0001503 216 0.012
positive regulation of protein phosphorylation GO:0001934 242 0.012
regionalization GO:0003002 337 0.012
regulation of nucleoside metabolic process GO:0009118 130 0.012
peptidyl lysine methylation GO:0018022 29 0.012
cellular response to transforming growth factor beta stimulus GO:0071560 88 0.012
b cell activation GO:0042113 161 0.012
response to organonitrogen compound GO:0010243 246 0.011
histone h4 k20 methylation GO:0034770 8 0.011
histone h3 k9 trimethylation GO:0036124 6 0.011
mitotic cell cycle GO:0000278 195 0.011
t cell activation GO:0042110 289 0.011
establishment of vesicle localization GO:0051650 81 0.011
negative regulation of cell proliferation GO:0008285 296 0.011
inorganic ion transmembrane transport GO:0098660 234 0.011
neuron apoptotic process GO:0051402 142 0.011
regulation of proteolysis GO:0030162 164 0.011
morphogenesis of embryonic epithelium GO:0016331 159 0.011
glycoprotein metabolic process GO:0009100 116 0.011
biomineral tissue development GO:0031214 64 0.011
cell activation involved in immune response GO:0002263 126 0.011
regulation of transmembrane transport GO:0034762 128 0.011
regulation of binding GO:0051098 111 0.011
nucleoside catabolic process GO:0009164 206 0.011
cellular divalent inorganic cation homeostasis GO:0072503 127 0.011
mrna metabolic process GO:0016071 84 0.011
regulation of neuron projection development GO:0010975 169 0.011
oocyte construction GO:0007308 2 0.011
leukocyte activation involved in immune response GO:0002366 126 0.011
compound eye development GO:0048749 1 0.011
response to peptide GO:1901652 136 0.011
response to inorganic substance GO:0010035 96 0.011
cellular response to growth factor stimulus GO:0071363 197 0.011
ribonucleoside triphosphate catabolic process GO:0009203 199 0.011
stem cell development GO:0048864 219 0.011
mitotic cytokinesis GO:0000281 4 0.011
regulation of vasculature development GO:1901342 88 0.011
regulation of voltage gated calcium channel activity GO:1901385 4 0.011
regulation of protein complex assembly GO:0043254 83 0.010
regulation of protein localization GO:0032880 231 0.010
protein alkylation GO:0008213 81 0.010
heart contraction GO:0060047 93 0.010
cellular response to lipid GO:0071396 145 0.010
neural precursor cell proliferation GO:0061351 121 0.010
blood coagulation GO:0007596 76 0.010
regulation of neuron death GO:1901214 134 0.010
negative regulation of neuron death GO:1901215 98 0.010
asymmetric stem cell division GO:0098722 3 0.010
negative regulation of cell activation GO:0050866 111 0.010
regulation of gtp catabolic process GO:0033124 113 0.010
regulation of ion transmembrane transport GO:0034765 119 0.010
response to transforming growth factor beta GO:0071559 88 0.010
myeloid leukocyte differentiation GO:0002573 119 0.010
myotube differentiation GO:0014902 105 0.010

Klhl28 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.016
disease of cellular proliferation DOID:14566 0 0.016
organ system cancer DOID:0050686 0 0.016
disease of anatomical entity DOID:7 0 0.015
nervous system disease DOID:863 0 0.015
musculoskeletal system disease DOID:17 0 0.014
connective tissue disease DOID:65 0 0.013
bone disease DOID:0080001 0 0.012