Mus musculus

43 known processes

Dner

delta/notch-like EGF-related receptor

(Aliases: Bret,A930026D19Rik,BET,MGC39059)

Dner biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of neuron differentiation GO:0045664 281 0.142
synaptic transmission GO:0007268 329 0.111
regulation of membrane potential GO:0042391 192 0.103
cell adhesion GO:0007155 329 0.076
regulation of neuron projection development GO:0010975 169 0.074
axonogenesis GO:0007409 274 0.067
cellular lipid metabolic process GO:0044255 323 0.057
regulation of anatomical structure size GO:0090066 178 0.055
vesicle localization GO:0051648 86 0.054
cellular ketone metabolic process GO:0042180 84 0.053
multicellular organismal signaling GO:0035637 91 0.049
positive regulation of nervous system development GO:0051962 221 0.048
positive regulation of neuron differentiation GO:0045666 141 0.046
establishment of vesicle localization GO:0051650 81 0.046
developmental growth involved in morphogenesis GO:0060560 138 0.046
regulation of cellular ketone metabolic process GO:0010565 66 0.045
transmembrane transport GO:0055085 412 0.045
regulation of secretion by cell GO:1903530 249 0.043
positive regulation of neuron projection development GO:0010976 79 0.041
response to organonitrogen compound GO:0010243 246 0.041
regulation of neurotransmitter levels GO:0001505 87 0.040
positive regulation of protein modification process GO:0031401 299 0.040
striated muscle tissue development GO:0014706 293 0.039
cell type specific apoptotic process GO:0097285 268 0.038
ensheathment of neurons GO:0007272 76 0.038
neuron migration GO:0001764 122 0.038
action potential GO:0001508 78 0.038
positive regulation of cell development GO:0010720 237 0.038
regulation of cellular component biogenesis GO:0044087 181 0.037
negative regulation of cell development GO:0010721 169 0.036
cellular protein complex assembly GO:0043623 116 0.036
regulation of secretion GO:0051046 274 0.036
regulation of system process GO:0044057 200 0.035
negative regulation of nervous system development GO:0051961 156 0.035
cellular amino acid metabolic process GO:0006520 103 0.035
spermatogenesis GO:0007283 284 0.034
cellular amine metabolic process GO:0044106 44 0.034
neuronal action potential GO:0019228 54 0.033
establishment of organelle localization GO:0051656 122 0.033
male gamete generation GO:0048232 285 0.033
regulation of cellular amine metabolic process GO:0033238 20 0.033
regulation of cellular amino acid metabolic process GO:0006521 5 0.032
membrane organization GO:0061024 245 0.031
regulation of cell projection organization GO:0031344 206 0.031
rna processing GO:0006396 105 0.031
positive regulation of cell projection organization GO:0031346 95 0.031
developmental maturation GO:0021700 193 0.031
learning or memory GO:0007611 148 0.031
dendrite development GO:0016358 115 0.031
negative regulation of cell proliferation GO:0008285 296 0.030
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.030
sensory organ morphogenesis GO:0090596 242 0.029
neuron projection extension GO:1990138 64 0.028
cytokine production GO:0001816 319 0.028
exocytosis GO:0006887 121 0.028
g protein coupled receptor signaling pathway GO:0007186 243 0.027
microtubule based process GO:0007017 236 0.027
nitrogen compound transport GO:0071705 271 0.027
regulation of actin nucleation GO:0051125 4 0.027
regulation of neuron death GO:1901214 134 0.027
telencephalon development GO:0021537 186 0.026
neuron neuron synaptic transmission GO:0007270 69 0.026
locomotory behavior GO:0007626 195 0.026
negative regulation of intracellular signal transduction GO:1902532 167 0.026
positive regulation of cellular amine metabolic process GO:0033240 5 0.025
organelle localization GO:0051640 179 0.025
learning GO:0007612 98 0.025
regulation of neuron apoptotic process GO:0043523 122 0.025
positive regulation of cellular component biogenesis GO:0044089 94 0.025
regulation of protein complex assembly GO:0043254 83 0.025
establishment of synaptic vesicle localization GO:0097480 57 0.025
skeletal system development GO:0001501 356 0.025
cellular response to dna damage stimulus GO:0006974 207 0.024
calcium ion dependent exocytosis GO:0017156 35 0.024
gliogenesis GO:0042063 141 0.024
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 43 0.024
neurotransmitter secretion GO:0007269 62 0.024
synaptic vesicle transport GO:0048489 57 0.024
fertilization GO:0009566 127 0.024
amine metabolic process GO:0009308 45 0.024
apoptotic signaling pathway GO:0097190 306 0.023
negative regulation of cellular component organization GO:0051129 194 0.023
peptidyl amino acid modification GO:0018193 336 0.023
mrna metabolic process GO:0016071 84 0.023
myelination GO:0042552 74 0.023
posttranscriptional regulation of gene expression GO:0010608 155 0.023
cation transmembrane transport GO:0098655 266 0.023
compound eye development GO:0048749 1 0.023
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.022
central nervous system neuron differentiation GO:0021953 162 0.022
regulation of organelle organization GO:0033043 289 0.022
embryonic epithelial tube formation GO:0001838 130 0.022
epithelial cell development GO:0002064 159 0.022
spermatid differentiation GO:0048515 115 0.021
germ cell development GO:0007281 185 0.021
rna splicing GO:0008380 54 0.021
negative regulation of molecular function GO:0044092 258 0.021
regulation of cellular component size GO:0032535 121 0.021
microtubule cytoskeleton organization GO:0000226 157 0.020
positive regulation of actin nucleation GO:0051127 3 0.020
muscle tissue development GO:0060537 308 0.020
cellular response to organonitrogen compound GO:0071417 145 0.020
extracellular matrix organization GO:0030198 147 0.020
ras protein signal transduction GO:0007265 77 0.020
single organism cell adhesion GO:0098602 156 0.020
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.020
regionalization GO:0003002 337 0.020
fat cell differentiation GO:0045444 160 0.019
developmental cell growth GO:0048588 84 0.019
chemotaxis GO:0006935 247 0.019
protein polymerization GO:0051258 57 0.019
carbohydrate metabolic process GO:0005975 230 0.019
blood vessel morphogenesis GO:0048514 285 0.019
mrna processing GO:0006397 63 0.019
mrna splicing via spliceosome GO:0000398 43 0.019
regulation of cytoskeleton organization GO:0051493 122 0.019
morphogenesis of a branching structure GO:0001763 203 0.019
regulation of hormone levels GO:0010817 211 0.019
neurotransmitter transport GO:0006836 76 0.019
axon ensheathment GO:0008366 76 0.019
digestive system development GO:0055123 200 0.019
negative regulation of protein metabolic process GO:0051248 282 0.019
negative regulation of neuron differentiation GO:0045665 101 0.019
organonitrogen compound biosynthetic process GO:1901566 192 0.019
vesicle organization GO:0016050 60 0.019
rna splicing via transesterification reactions GO:0000375 43 0.019
intrinsic apoptotic signaling pathway GO:0097193 132 0.018
positive regulation of secretion by cell GO:1903532 114 0.018
camera type eye development GO:0043010 266 0.018
skeletal muscle organ development GO:0060538 163 0.018
respiratory gaseous exchange GO:0007585 43 0.018
extracellular structure organization GO:0043062 148 0.018
phospholipid metabolic process GO:0006644 87 0.018
microtubule based movement GO:0007018 84 0.018
regulation of protein localization GO:0032880 231 0.018
regulation of cell motility GO:2000145 236 0.018
male courtship behavior GO:0008049 2 0.018
cation transport GO:0006812 399 0.018
chromatin organization GO:0006325 206 0.018
regulation of cytokine production GO:0001817 266 0.018
spermatid development GO:0007286 108 0.018
organophosphate biosynthetic process GO:0090407 122 0.017
regulation of cell adhesion GO:0030155 154 0.017
nucleotide metabolic process GO:0009117 332 0.017
synaptic vesicle priming GO:0016082 8 0.017
morphogenesis of embryonic epithelium GO:0016331 159 0.017
single organismal cell cell adhesion GO:0016337 131 0.017
digestive tract morphogenesis GO:0048546 147 0.017
membrane depolarization GO:0051899 64 0.017
protein localization to organelle GO:0033365 185 0.017
synaptic vesicle localization GO:0097479 59 0.017
regulation of response to wounding GO:1903034 189 0.017
forebrain development GO:0030900 302 0.017
lipid biosynthetic process GO:0008610 179 0.017
purine ribonucleotide metabolic process GO:0009150 290 0.016
small gtpase mediated signal transduction GO:0007264 97 0.016
ribose phosphate metabolic process GO:0019693 291 0.016
digestive tract development GO:0048565 190 0.016
fatty acid metabolic process GO:0006631 121 0.016
regulation of cell cycle GO:0051726 281 0.016
immune effector process GO:0002252 321 0.016
transmission of nerve impulse GO:0019226 76 0.016
carbohydrate derivative biosynthetic process GO:1901137 183 0.016
response to extracellular stimulus GO:0009991 127 0.016
actin filament polymerization GO:0030041 44 0.016
wound healing GO:0042060 157 0.016
regulation of feeding behavior GO:0060259 3 0.016
ossification GO:0001503 216 0.016
cardiac chamber development GO:0003205 108 0.016
multicellular organismal homeostasis GO:0048871 164 0.016
ribonucleotide metabolic process GO:0009259 291 0.016
sensory perception GO:0007600 245 0.016
neural tube development GO:0021915 160 0.016
blood circulation GO:0008015 195 0.016
response to nutrient levels GO:0031667 109 0.016
cell fate commitment GO:0045165 210 0.016
actin polymerization or depolymerization GO:0008154 54 0.016
regulation of mrna metabolic process GO:1903311 43 0.016
dephosphorylation GO:0016311 129 0.016
positive regulation of protein phosphorylation GO:0001934 242 0.016
negative regulation of cellular protein metabolic process GO:0032269 247 0.016
neuron apoptotic process GO:0051402 142 0.016
oxidation reduction process GO:0055114 342 0.015
intracellular protein transport GO:0006886 204 0.015
inflammatory response GO:0006954 244 0.015
regulation of exocytosis GO:0017157 61 0.015
cell maturation GO:0048469 127 0.015
regulation of lipid metabolic process GO:0019216 118 0.015
neuron death GO:0070997 154 0.015
adult behavior GO:0030534 135 0.015
regulation of mrna splicing via spliceosome GO:0048024 32 0.015
tube formation GO:0035148 140 0.015
nucleobase containing small molecule metabolic process GO:0055086 352 0.015
inorganic cation transmembrane transport GO:0098662 207 0.015
negative regulation of organelle organization GO:0010639 90 0.015
lymphocyte differentiation GO:0030098 242 0.015
synapse organization GO:0050808 125 0.015
regulation of hydrolase activity GO:0051336 246 0.015
epithelial tube morphogenesis GO:0060562 303 0.015
carbohydrate homeostasis GO:0033500 128 0.015
inorganic ion transmembrane transport GO:0098660 234 0.015
purine containing compound metabolic process GO:0072521 311 0.015
organelle assembly GO:0070925 177 0.015
respiratory system development GO:0060541 190 0.015
peptide hormone secretion GO:0030072 109 0.015
axon guidance GO:0007411 141 0.015
regulation of transferase activity GO:0051338 263 0.015
actin cytoskeleton organization GO:0030036 220 0.015
ribonucleoside metabolic process GO:0009119 245 0.014
respiratory tube development GO:0030323 167 0.014
hormone secretion GO:0046879 128 0.014
embryonic organ morphogenesis GO:0048562 276 0.014
sequestering of calcium ion GO:0051208 18 0.014
regulation of rna splicing GO:0043484 37 0.014
generation of precursor metabolites and energy GO:0006091 103 0.014
regulation of neuronal synaptic plasticity GO:0048168 30 0.014
multi multicellular organism process GO:0044706 109 0.014
regulation of cell activation GO:0050865 289 0.014
neural precursor cell proliferation GO:0061351 121 0.014
olfactory learning GO:0008355 2 0.014
chromatin modification GO:0016568 187 0.014
response to organic cyclic compound GO:0014070 198 0.014
positive regulation of secretion GO:0051047 130 0.014
negative regulation of neuron projection development GO:0010977 50 0.014
cell recognition GO:0008037 83 0.014
peripheral nervous system neuron axonogenesis GO:0048936 3 0.014
bmp signaling pathway GO:0030509 93 0.014
regulation of ion transport GO:0043269 215 0.014
cellular response to peptide GO:1901653 92 0.014
cell cell adhesion via plasma membrane adhesion molecules GO:0098742 40 0.014
covalent chromatin modification GO:0016569 163 0.014
pole plasm assembly GO:0007315 2 0.014
regulation of synaptic plasticity GO:0048167 87 0.014
regulation of cellular catabolic process GO:0031329 242 0.014
positive regulation of organelle organization GO:0010638 128 0.014
gland development GO:0048732 330 0.014
regulation of vesicle mediated transport GO:0060627 139 0.014
regulation of homeostatic process GO:0032844 182 0.014
negative regulation of neuron death GO:1901215 98 0.014
regulation of proteolysis GO:0030162 164 0.014
cellular response to lipid GO:0071396 145 0.014
reactive oxygen species metabolic process GO:0072593 84 0.014
glycoprotein metabolic process GO:0009100 116 0.013
regulation of blood circulation GO:1903522 93 0.013
regulation of actin filament based process GO:0032970 99 0.013
regulation of action potential GO:0098900 4 0.013
photoreceptor cell differentiation GO:0046530 52 0.013
cytoplasmic transport GO:0016482 234 0.013
regulation of intracellular transport GO:0032386 159 0.013
regulation of establishment of protein localization GO:0070201 181 0.013
ear development GO:0043583 200 0.013
protein ubiquitination GO:0016567 171 0.013
oocyte construction GO:0007308 2 0.013
glycerolipid metabolic process GO:0046486 122 0.013
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.013
protein modification by small protein conjugation or removal GO:0070647 207 0.013
regulation of mrna processing GO:0050684 41 0.013
histone modification GO:0016570 159 0.013
protein modification by small protein conjugation GO:0032446 187 0.013
t cell activation GO:0042110 289 0.013
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.013
cellular homeostasis GO:0019725 240 0.013
regulation of protein kinase activity GO:0045859 232 0.013
hindbrain development GO:0030902 128 0.013
regulation of postsynaptic membrane potential GO:0060078 48 0.012
peptide transport GO:0015833 133 0.012
positive regulation of apoptotic process GO:0043065 217 0.012
cell cell adhesion GO:0098609 41 0.012
response to radiation GO:0009314 165 0.012
midgut development GO:0007494 4 0.012
single fertilization GO:0007338 82 0.012
stem cell maintenance GO:0019827 130 0.012
pharynx development GO:0060465 1 0.012
maintenance of location GO:0051235 89 0.012
tube closure GO:0060606 91 0.012
response to light stimulus GO:0009416 135 0.012
sperm motility GO:0030317 47 0.012
regulation of mapk cascade GO:0043408 248 0.012
oocyte axis specification GO:0007309 2 0.012
muscle cell differentiation GO:0042692 261 0.012
cerebellum development GO:0021549 77 0.012
divalent inorganic cation transport GO:0072511 178 0.012
endomembrane system organization GO:0010256 147 0.012
regulation of defense response GO:0031347 233 0.012
methylation GO:0032259 134 0.012
circulatory system process GO:0003013 197 0.012
regulation of actin cytoskeleton organization GO:0032956 84 0.012
synaptic vesicle exocytosis GO:0016079 26 0.012
central nervous system neuron development GO:0021954 67 0.012
circadian rhythm GO:0007623 114 0.012
rho protein signal transduction GO:0007266 32 0.012
lung development GO:0030324 164 0.012
cellular carbohydrate metabolic process GO:0044262 119 0.012
stem cell differentiation GO:0048863 268 0.012
glial cell development GO:0021782 54 0.012
ion transmembrane transport GO:0034220 361 0.011
cell junction assembly GO:0034329 52 0.011
regulation of apoptotic signaling pathway GO:2001233 197 0.011
cellular protein catabolic process GO:0044257 155 0.011
purine nucleotide metabolic process GO:0006163 302 0.011
ameboidal type cell migration GO:0001667 128 0.011
multi organism behavior GO:0051705 62 0.011
nucleoside metabolic process GO:0009116 246 0.011
primary neural tube formation GO:0014020 95 0.011
stem cell development GO:0048864 219 0.011
organonitrogen compound catabolic process GO:1901565 264 0.011
hematopoietic progenitor cell differentiation GO:0002244 143 0.011
membrane lipid metabolic process GO:0006643 53 0.011
lipid modification GO:0030258 65 0.011
peptidyl tyrosine modification GO:0018212 145 0.011
muscle system process GO:0003012 141 0.011
regulation of ossification GO:0030278 112 0.011
epithelial cell proliferation GO:0050673 174 0.011
mapk cascade GO:0000165 281 0.011
epithelial tube formation GO:0072175 130 0.011
regulation of cell size GO:0008361 72 0.011
bone development GO:0060348 120 0.011
sensory perception of sound GO:0007605 97 0.011
establishment or maintenance of cell polarity GO:0007163 86 0.011
morphogenesis of a branching epithelium GO:0061138 193 0.011
gastrulation GO:0007369 116 0.011
modification dependent protein catabolic process GO:0019941 133 0.011
cognition GO:0050890 149 0.011
positive regulation of kinase activity GO:0033674 155 0.011
sa node cell action potential GO:0086015 4 0.011
regulation of cell growth GO:0001558 91 0.011
detection of stimulus GO:0051606 84 0.011
lateral inhibition GO:0046331 1 0.011
heart morphogenesis GO:0003007 178 0.011
cardiac ventricle development GO:0003231 83 0.011
peptide secretion GO:0002790 114 0.011
monocarboxylic acid metabolic process GO:0032787 191 0.011
urogenital system development GO:0001655 261 0.011
anion transport GO:0006820 177 0.011
endocytosis GO:0006897 168 0.011
cellular component assembly involved in morphogenesis GO:0010927 139 0.011
cellular response to carbohydrate stimulus GO:0071322 50 0.011
wnt signaling pathway GO:0016055 188 0.011
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.011
regulation of intrinsic apoptotic signaling pathway GO:2001242 61 0.011
skeletal system morphogenesis GO:0048705 203 0.011
amide transport GO:0042886 138 0.011
divalent metal ion transport GO:0070838 172 0.011
regulation of metal ion transport GO:0010959 106 0.010
cellular response to peptide hormone stimulus GO:0071375 92 0.010
leukocyte mediated immunity GO:0002443 174 0.010
engulfment of apoptotic cell GO:0043652 3 0.010
intracellular mrna localization GO:0008298 4 0.010
nucleoside phosphate metabolic process GO:0006753 338 0.010
canonical wnt signaling pathway GO:0060070 130 0.010
segmentation GO:0035282 93 0.010
establishment of glial blood brain barrier GO:0060857 2 0.010
sensory perception of mechanical stimulus GO:0050954 107 0.010
ubiquitin dependent protein catabolic process GO:0006511 129 0.010
positive regulation of programmed cell death GO:0043068 218 0.010
cellular response to ammonium ion GO:0071242 2 0.010
establishment of protein localization to organelle GO:0072594 118 0.010
regulation of organ morphogenesis GO:2000027 144 0.010
response to growth factor GO:0070848 198 0.010
metencephalon development GO:0022037 89 0.010
protein catabolic process GO:0030163 221 0.010
positive regulation of cell death GO:0010942 224 0.010
regulation of neurotransmitter secretion GO:0046928 29 0.010
glycerolipid biosynthetic process GO:0045017 50 0.010
neural tube formation GO:0001841 108 0.010
regulation of cellular response to stress GO:0080135 159 0.010
regulation of kinase activity GO:0043549 249 0.010
neuromuscular process controlling balance GO:0050885 59 0.010
gonad morphogenesis GO:0035262 1 0.010
glial cell differentiation GO:0010001 131 0.010

Dner disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
nervous system disease DOID:863 0 0.031
disease of anatomical entity DOID:7 0 0.031
sensory system disease DOID:0050155 0 0.014
central nervous system disease DOID:331 0 0.011
eye and adnexa disease DOID:1492 0 0.011
eye disease DOID:5614 0 0.011
retinal degeneration DOID:8466 0 0.011
retinal disease DOID:5679 0 0.011
organ system cancer DOID:0050686 0 0.010
disease of cellular proliferation DOID:14566 0 0.010
cancer DOID:162 0 0.010