Mus musculus

363 known processes

Mecp2

methyl CpG binding protein 2

(Aliases: Mbd5,1500041B07Rik,D630021H01Rik,BB130002,WBP10)

Mecp2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
stem cell development GO:0048864 219 0.961
dna metabolic process GO:0006259 303 0.957
regulation of dna endoreduplication GO:0032875 3 0.903
male gamete generation GO:0048232 285 0.892
mitotic sister chromatid cohesion GO:0007064 1 0.889
synaptonemal complex assembly GO:0007130 13 0.869
stem cell differentiation GO:0048863 268 0.830
stem cell maintenance GO:0019827 130 0.760
negative regulation of dna dependent dna replication GO:2000104 1 0.753
regulation of dna dependent dna replication GO:0090329 8 0.735
forebrain development GO:0030900 302 0.729
cellular ketone metabolic process GO:0042180 84 0.683
regulation of cellular amine metabolic process GO:0033238 20 0.669
peptidyl amino acid modification GO:0018193 336 0.663
axonogenesis GO:0007409 274 0.635
amine metabolic process GO:0009308 45 0.634
dendrite development GO:0016358 115 0.584
dna dependent dna replication GO:0006261 24 0.561
dna endoreduplication GO:0042023 4 0.554
cellular amine metabolic process GO:0044106 44 0.549
double strand break repair GO:0006302 48 0.539
spermatogenesis GO:0007283 284 0.536
neuron projection guidance GO:0097485 141 0.529
regulation of cellular ketone metabolic process GO:0010565 66 0.522
cellular amino acid metabolic process GO:0006520 103 0.509
synapsis GO:0007129 34 0.509
dna replication GO:0006260 52 0.488
chemotaxis GO:0006935 247 0.483
nucleobase containing small molecule metabolic process GO:0055086 352 0.480
gonad development GO:0008406 141 0.477
dna replication independent nucleosome assembly GO:0006336 1 0.474
endocytosis GO:0006897 168 0.455
regulation of cell cycle process GO:0010564 160 0.455
muscle tissue development GO:0060537 308 0.453
apoptotic signaling pathway GO:0097190 306 0.450
purine nucleotide metabolic process GO:0006163 302 0.450
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.445
regulation of cellular amino acid metabolic process GO:0006521 5 0.444
stress activated mapk cascade GO:0051403 80 0.436
meiotic sister chromatid segregation GO:0045144 6 0.415
lung development GO:0030324 164 0.412
regulation of cell cycle GO:0051726 281 0.405
histone acetylation GO:0016573 41 0.402
dna repair GO:0006281 107 0.398
locomotory behavior GO:0007626 195 0.393
appendage development GO:0048736 166 0.385
negative regulation of cell proliferation GO:0008285 296 0.382
response to organic cyclic compound GO:0014070 198 0.376
positive regulation of transcription from rna polymerase ii promoter in response to stress GO:0036003 3 0.374
chromatin organization GO:0006325 206 0.368
dna recombination GO:0006310 92 0.363
cellular response to external stimulus GO:0071496 88 0.362
synaptonemal complex organization GO:0070193 15 0.353
regulation of mitotic cell cycle GO:0007346 126 0.349
cellular response to dna damage stimulus GO:0006974 207 0.347
wnt signaling pathway GO:0016055 188 0.347
protein acylation GO:0043543 64 0.344
regulation of nuclear cell cycle dna replication GO:0033262 2 0.343
axon guidance GO:0007411 141 0.339
microtubule based process GO:0007017 236 0.332
negative regulation of dna replication GO:0008156 4 0.329
cellular response to inorganic substance GO:0071241 37 0.325
regulation of neuron differentiation GO:0045664 281 0.322
negative regulation of gene expression epigenetic GO:0045814 15 0.310
regulation of binding GO:0051098 111 0.300
learning or memory GO:0007611 148 0.293
peptidyl lysine acetylation GO:0018394 45 0.291
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.288
purine containing compound metabolic process GO:0072521 311 0.288
chromatin modification GO:0016568 187 0.279
male sex differentiation GO:0046661 109 0.275
regulation of neuron projection development GO:0010975 169 0.270
regionalization GO:0003002 337 0.269
gliogenesis GO:0042063 141 0.264
negative regulation of cell cycle GO:0045786 123 0.260
cell maturation GO:0048469 127 0.259
cellular response to starvation GO:0009267 57 0.253
mapk cascade GO:0000165 281 0.252
circadian rhythm GO:0007623 114 0.245
histone methylation GO:0016571 71 0.243
epithelial cell development GO:0002064 159 0.239
dna packaging GO:0006323 30 0.238
dna conformation change GO:0071103 37 0.238
rhythmic process GO:0048511 174 0.232
anatomical structure homeostasis GO:0060249 145 0.229
regulation of jnk cascade GO:0046328 62 0.225
chromatin silencing GO:0006342 15 0.219
cognition GO:0050890 149 0.215
lymphocyte differentiation GO:0030098 242 0.214
meiotic sister chromatid cohesion GO:0051177 6 0.214
ribonucleoside triphosphate metabolic process GO:0009199 220 0.211
purine ribonucleotide metabolic process GO:0009150 290 0.208
respiratory tube development GO:0030323 167 0.208
ribonucleotide metabolic process GO:0009259 291 0.204
cell fate commitment GO:0045165 210 0.204
central nervous system neuron differentiation GO:0021953 162 0.202
nucleotide metabolic process GO:0009117 332 0.202
dna alkylation GO:0006305 43 0.201
negative regulation of cellular component organization GO:0051129 194 0.200
response to light stimulus GO:0009416 135 0.199
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.198
regulation of mapk cascade GO:0043408 248 0.197
cellular response to nutrient levels GO:0031669 64 0.193
intrinsic apoptotic signaling pathway GO:0097193 132 0.191
striated muscle tissue development GO:0014706 293 0.187
genitalia development GO:0048806 37 0.184
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.182
olfactory learning GO:0008355 2 0.182
cerebellum development GO:0021549 77 0.181
negative regulation of cell development GO:0010721 169 0.180
regulation of lymphocyte activation GO:0051249 240 0.180
negative regulation of neuron differentiation GO:0045665 101 0.180
meiotic nuclear division GO:0007126 115 0.175
dna dependent dna replication maintenance of fidelity GO:0045005 3 0.174
regulation of cellular catabolic process GO:0031329 242 0.172
associative learning GO:0008306 61 0.169
dna modification GO:0006304 50 0.168
protein localization to membrane GO:0072657 108 0.167
adult behavior GO:0030534 135 0.166
activation of immune response GO:0002253 138 0.166
jnk cascade GO:0007254 72 0.166
regulation of dna replication GO:0006275 17 0.165
neuron maturation GO:0042551 29 0.163
embryonic limb morphogenesis GO:0030326 126 0.160
sister chromatid cohesion GO:0007062 12 0.160
development of primary sexual characteristics GO:0045137 143 0.158
myeloid cell homeostasis GO:0002262 114 0.157
carbohydrate metabolic process GO:0005975 230 0.156
neural tube development GO:0021915 160 0.155
cellular response to extracellular stimulus GO:0031668 81 0.151
skeletal system development GO:0001501 356 0.150
positive regulation of nervous system development GO:0051962 221 0.145
glial cell differentiation GO:0010001 131 0.144
nitrogen compound transport GO:0071705 271 0.143
myeloid cell differentiation GO:0030099 233 0.141
internal peptidyl lysine acetylation GO:0018393 42 0.141
embryonic appendage morphogenesis GO:0035113 126 0.140
negative regulation of nervous system development GO:0051961 156 0.138
respiratory system development GO:0060541 190 0.138
chromatin assembly GO:0031497 13 0.136
negative regulation of cellular amine metabolic process GO:0033239 1 0.135
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.134
germ cell development GO:0007281 185 0.133
cellularization GO:0007349 1 0.132
cellular carbohydrate metabolic process GO:0044262 119 0.132
immune response activating signal transduction GO:0002757 116 0.132
neuron apoptotic process GO:0051402 142 0.127
homeostasis of number of cells GO:0048872 210 0.127
mitotic cell cycle GO:0000278 195 0.124
spermatid development GO:0007286 108 0.123
telencephalon development GO:0021537 186 0.123
neuron death GO:0070997 154 0.122
erythrocyte differentiation GO:0030218 88 0.122
lipid localization GO:0010876 126 0.121
limb morphogenesis GO:0035108 149 0.120
extrinsic apoptotic signaling pathway GO:0097191 126 0.120
purine ribonucleoside metabolic process GO:0046128 241 0.119
regulation of neural precursor cell proliferation GO:2000177 70 0.119
positive regulation of cellular amine metabolic process GO:0033240 5 0.118
cellular response to organonitrogen compound GO:0071417 145 0.117
regulation of secretion GO:0051046 274 0.116
stress activated protein kinase signaling cascade GO:0031098 81 0.114
histone lysine methylation GO:0034968 50 0.112
calcium mediated signaling GO:0019722 46 0.111
maintenance of location GO:0051235 89 0.110
signal transduction by p53 class mediator GO:0072331 51 0.109
organic hydroxy compound metabolic process GO:1901615 203 0.108
carbohydrate derivative biosynthetic process GO:1901137 183 0.107
regulation of cell migration GO:0030334 219 0.107
developmental maturation GO:0021700 193 0.105
mesenchyme development GO:0060485 152 0.104
negative regulation of cell growth GO:0030308 44 0.102
negative regulation of protein metabolic process GO:0051248 282 0.102
positive regulation of chromosome organization GO:2001252 33 0.099
seminiferous tubule development GO:0072520 14 0.098
chromatin remodeling GO:0006338 32 0.098
regulation of leukocyte differentiation GO:1902105 159 0.097
ribose phosphate metabolic process GO:0019693 291 0.097
blood vessel morphogenesis GO:0048514 285 0.096
positive regulation of protein phosphorylation GO:0001934 242 0.096
histone h3 acetylation GO:0043966 14 0.096
gland development GO:0048732 330 0.096
organic hydroxy compound transport GO:0015850 93 0.095
neuromuscular process GO:0050905 99 0.094
ribonucleoside catabolic process GO:0042454 206 0.094
methylation GO:0032259 134 0.094
response to inorganic substance GO:0010035 96 0.094
neurotransmitter secretion GO:0007269 62 0.093
endomembrane system organization GO:0010256 147 0.092
regulation of transcription by chromatin organization GO:0034401 0 0.092
positive regulation of homeostatic process GO:0032846 64 0.092
skeletal muscle organ development GO:0060538 163 0.091
posttranscriptional regulation of gene expression GO:0010608 155 0.091
regulation of protein kinase activity GO:0045859 232 0.089
regulation of neurotransmitter levels GO:0001505 87 0.089
embryonic organ morphogenesis GO:0048562 276 0.087
purine nucleoside triphosphate metabolic process GO:0009144 226 0.087
sertoli cell differentiation GO:0060008 18 0.086
spermatid differentiation GO:0048515 115 0.086
positive regulation of binding GO:0051099 49 0.086
lipid transport GO:0006869 98 0.086
regulation of autophagy GO:0010506 30 0.086
oxidation reduction process GO:0055114 342 0.086
cellular response to hormone stimulus GO:0032870 150 0.085
regulation of mitotic cell cycle phase transition GO:1901990 73 0.085
development of primary male sexual characteristics GO:0046546 88 0.083
neural precursor cell proliferation GO:0061351 121 0.081
exocytosis GO:0006887 121 0.081
negative regulation of cell morphogenesis involved in differentiation GO:0010771 48 0.081
regulation of insulin receptor signaling pathway GO:0046626 21 0.081
positive regulation of kinase activity GO:0033674 155 0.081
developmental cell growth GO:0048588 84 0.081
heart morphogenesis GO:0003007 178 0.080
cellular carbohydrate catabolic process GO:0044275 15 0.080
positive regulation of protein modification process GO:0031401 299 0.079
internal protein amino acid acetylation GO:0006475 42 0.079
organic cyclic compound catabolic process GO:1901361 295 0.078
dna damage response signal transduction by p53 class mediator GO:0030330 19 0.078
negative regulation of apoptotic signaling pathway GO:2001234 104 0.078
cellular response to organic cyclic compound GO:0071407 87 0.077
peptidyl tyrosine modification GO:0018212 145 0.077
response to organonitrogen compound GO:0010243 246 0.077
regulation of system process GO:0044057 200 0.077
ribonucleoside metabolic process GO:0009119 245 0.077
nuclear dna replication GO:0033260 3 0.076
macromolecule methylation GO:0043414 120 0.076
male courtship behavior GO:0008049 2 0.076
regulation of myeloid cell differentiation GO:0045637 96 0.074
leukocyte differentiation GO:0002521 342 0.074
negative regulation of cell cycle process GO:0010948 69 0.073
regulation of membrane potential GO:0042391 192 0.073
embryonic hemopoiesis GO:0035162 23 0.073
regulation of transcription from rna polymerase ii promoter in response to stress GO:0043618 8 0.073
dna methylation GO:0006306 43 0.073
purine nucleoside catabolic process GO:0006152 205 0.071
cardiac muscle tissue development GO:0048738 130 0.071
regulation of chromatin silencing GO:0031935 2 0.071
nucleoside phosphate biosynthetic process GO:1901293 79 0.070
regulation of cellular carbohydrate metabolic process GO:0010675 75 0.070
ribonucleoside monophosphate catabolic process GO:0009158 57 0.069
cellular lipid metabolic process GO:0044255 323 0.069
cyclic nucleotide metabolic process GO:0009187 59 0.069
energy reserve metabolic process GO:0006112 39 0.069
positive regulation of cell cycle GO:0045787 92 0.069
regulation of peptidyl serine phosphorylation GO:0033135 39 0.069
purine nucleoside metabolic process GO:0042278 241 0.068
limb development GO:0060173 166 0.068
cellular response to acid chemical GO:0071229 68 0.068
regulation of circadian rhythm GO:0042752 58 0.067
autophagy GO:0006914 45 0.067
purine nucleoside triphosphate catabolic process GO:0009146 203 0.066
urogenital system development GO:0001655 261 0.066
skin development GO:0043588 220 0.066
cytoskeleton dependent intracellular transport GO:0030705 50 0.066
regulation of cell cycle phase transition GO:1901987 77 0.066
monosaccharide metabolic process GO:0005996 106 0.066
regulation of protein localization GO:0032880 231 0.065
ribonucleoside triphosphate catabolic process GO:0009203 199 0.065
positive regulation of transcription elongation from rna polymerase ii promoter GO:0032968 2 0.065
glucose metabolic process GO:0006006 92 0.064
regulation of apoptotic signaling pathway GO:2001233 197 0.064
cell fate specification GO:0001708 72 0.064
epidermis development GO:0008544 187 0.064
regulation of neuron apoptotic process GO:0043523 122 0.064
heterocycle catabolic process GO:0046700 280 0.064
regulation of receptor activity GO:0010469 41 0.064
mesoderm development GO:0007498 100 0.064
positive regulation of dna templated transcription elongation GO:0032786 2 0.063
sister chromatid segregation GO:0000819 20 0.063
pallium development GO:0021543 120 0.063
cilium assembly GO:0042384 81 0.063
neurotransmitter transport GO:0006836 76 0.063
multicellular organism growth GO:0035264 161 0.063
protein localization to plasma membrane GO:0072659 57 0.062
kidney development GO:0001822 213 0.062
regulation of cell motility GO:2000145 236 0.062
hindbrain morphogenesis GO:0021575 46 0.062
myeloid leukocyte differentiation GO:0002573 119 0.062
translation GO:0006412 93 0.062
diencephalon development GO:0021536 63 0.061
phagocytosis GO:0006909 66 0.061
camera type eye development GO:0043010 266 0.061
synapse organization GO:0050808 125 0.061
circulatory system process GO:0003013 197 0.060
multi organism reproductive behavior GO:0044705 29 0.060
i kappab kinase nf kappab signaling GO:0007249 85 0.060
male gonad development GO:0008584 88 0.059
negative regulation of neuron projection development GO:0010977 50 0.059
purine nucleotide catabolic process GO:0006195 211 0.059
negative regulation of mitotic cell cycle phase transition GO:1901991 45 0.059
regulation of cell growth GO:0001558 91 0.058
negative regulation of defense response GO:0031348 77 0.058
double strand break repair via homologous recombination GO:0000724 21 0.058
negative regulation of phagocytosis GO:0050765 4 0.058
negative regulation of synapse assembly GO:0051964 3 0.057
axoneme assembly GO:0035082 15 0.057
regulation of translation GO:0006417 71 0.057
regulation of organ morphogenesis GO:2000027 144 0.057
gene silencing GO:0016458 38 0.057
regulation of carbohydrate metabolic process GO:0006109 75 0.056
positive regulation of transferase activity GO:0051347 167 0.056
aromatic compound catabolic process GO:0019439 286 0.056
regulation of protein targeting GO:1903533 61 0.056
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.055
sensory perception GO:0007600 245 0.055
regulation of lipid metabolic process GO:0019216 118 0.055
mitotic cell cycle process GO:1903047 159 0.055
protein localization to organelle GO:0033365 185 0.055
regulation of intracellular transport GO:0032386 159 0.055
cellular ion homeostasis GO:0006873 165 0.054
regulation of hydrolase activity GO:0051336 246 0.054
positive regulation of cellular catabolic process GO:0031331 148 0.054
somitogenesis GO:0001756 69 0.054
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 45 0.054
regulation of postsynaptic membrane potential GO:0060078 48 0.054
sterol homeostasis GO:0055092 45 0.053
chromosome segregation GO:0007059 48 0.053
regulation of erbb signaling pathway GO:1901184 16 0.053
regulation of synapse structural plasticity GO:0051823 4 0.053
purine ribonucleotide catabolic process GO:0009154 208 0.053
regulation of cellular component size GO:0032535 121 0.053
response to peptide hormone GO:0043434 127 0.053
multi multicellular organism process GO:0044706 109 0.053
glucose homeostasis GO:0042593 128 0.053
insulin receptor signaling pathway GO:0008286 49 0.053
hindbrain development GO:0030902 128 0.053
cellular response to growth factor stimulus GO:0071363 197 0.053
regulation of proteolysis GO:0030162 164 0.052
second messenger mediated signaling GO:0019932 73 0.052
protein kinase b signaling GO:0043491 74 0.052
signal transduction in response to dna damage GO:0042770 21 0.052
response to radiation GO:0009314 165 0.052
epithelial tube morphogenesis GO:0060562 303 0.052
ribonucleoside monophosphate metabolic process GO:0009161 80 0.052
nuclear division GO:0000280 158 0.052
multicellular organismal response to stress GO:0033555 62 0.052
glycosyl compound metabolic process GO:1901657 246 0.052
positive regulation of cell cycle process GO:0090068 61 0.051
positive regulation of cell development GO:0010720 237 0.051
activation of innate immune response GO:0002218 56 0.051
cellular response to peptide GO:1901653 92 0.051
regulation of ion transport GO:0043269 215 0.050
cytokine production GO:0001816 319 0.050
spinal cord development GO:0021510 81 0.050
nucleoside triphosphate catabolic process GO:0009143 205 0.050
response to growth factor GO:0070848 198 0.050
regulation of kinase activity GO:0043549 249 0.049
peptidyl tyrosine phosphorylation GO:0018108 143 0.049
regulation of gliogenesis GO:0014013 50 0.049
mesenchymal cell development GO:0014031 93 0.049
response to extracellular stimulus GO:0009991 127 0.049
neural tube patterning GO:0021532 43 0.049
positive regulation of protein kinase activity GO:0045860 144 0.049
peptidyl serine modification GO:0018209 83 0.049
regulation of cytokine production GO:0001817 266 0.049
organic anion transport GO:0015711 137 0.049
negative regulation of cell cycle phase transition GO:1901988 48 0.048
regulation of protein processing GO:0070613 96 0.048
positive regulation of neuron differentiation GO:0045666 141 0.048
regulation of feeding behavior GO:0060259 3 0.048
cellular response to drug GO:0035690 15 0.048
peptidyl lysine modification GO:0018205 77 0.048
regulation of cell projection organization GO:0031344 206 0.048
cellular component assembly involved in morphogenesis GO:0010927 139 0.048
hematopoietic progenitor cell differentiation GO:0002244 143 0.047
meiosis ii GO:0007135 7 0.047
renal system development GO:0072001 225 0.047
response to drug GO:0042493 75 0.047
organonitrogen compound catabolic process GO:1901565 264 0.047
regulation of defense response GO:0031347 233 0.047
response to nutrient levels GO:0031667 109 0.046
carbohydrate homeostasis GO:0033500 128 0.046
protein processing GO:0016485 163 0.046
regulation of cell activation GO:0050865 289 0.046
synaptic transmission GO:0007268 329 0.046
ribonucleotide catabolic process GO:0009261 208 0.046
peptidyl serine phosphorylation GO:0018105 74 0.046
mitotic sister chromatid segregation GO:0000070 14 0.046
carbohydrate catabolic process GO:0016052 32 0.045
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.045
positive regulation of defense response GO:0031349 124 0.045
negative regulation of immune system process GO:0002683 209 0.045
purine nucleotide biosynthetic process GO:0006164 65 0.045
negative regulation of phosphorylation GO:0042326 166 0.045
protein localization to nucleus GO:0034504 121 0.045
erbb signaling pathway GO:0038127 32 0.045
cation transport GO:0006812 399 0.044
embryonic skeletal system morphogenesis GO:0048704 91 0.044
branching morphogenesis of an epithelial tube GO:0048754 159 0.044
cellular chemical homeostasis GO:0055082 215 0.044
positive regulation of hydrolase activity GO:0051345 148 0.044
regulation of axon extension GO:0030516 43 0.044
negative regulation of growth GO:0045926 99 0.044
macroautophagy GO:0016236 21 0.044
covalent chromatin modification GO:0016569 163 0.043
sensory organ morphogenesis GO:0090596 242 0.043
glial cell migration GO:0008347 7 0.043
microtubule cytoskeleton organization GO:0000226 157 0.042
meiotic cell cycle GO:0051321 122 0.042
microtubule based movement GO:0007018 84 0.042
columnar cuboidal epithelial cell differentiation GO:0002065 82 0.042
genetic imprinting GO:0071514 27 0.042
molting cycle GO:0042303 90 0.041
gastrulation GO:0007369 116 0.041
extracellular matrix organization GO:0030198 147 0.041
nucleoside phosphate catabolic process GO:1901292 222 0.041
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.041
memory GO:0007613 58 0.041
segmentation GO:0035282 93 0.041
ossification GO:0001503 216 0.041
regulation of glucose metabolic process GO:0010906 60 0.041
regulation of endocytosis GO:0030100 69 0.041
synapse assembly GO:0007416 56 0.041
feeding behavior GO:0007631 62 0.041
regulation of secretion by cell GO:1903530 249 0.041
carbohydrate derivative catabolic process GO:1901136 231 0.040
negative regulation of lymphocyte activation GO:0051250 91 0.040
blood circulation GO:0008015 195 0.040
nucleotide biosynthetic process GO:0009165 78 0.040
neuron migration GO:0001764 122 0.040
digestive tract morphogenesis GO:0048546 147 0.040
lipid homeostasis GO:0055088 63 0.040
regulation of organ growth GO:0046620 61 0.040
organ growth GO:0035265 117 0.040
cellular homeostasis GO:0019725 240 0.040
regulation of establishment of protein localization GO:0070201 181 0.040
sperm individualization GO:0007291 1 0.040
cholesterol homeostasis GO:0042632 44 0.040
negative regulation of cell projection organization GO:0031345 56 0.039
mitotic nuclear division GO:0007067 48 0.039
regulation of homeostatic process GO:0032844 182 0.039
regulation of ras protein signal transduction GO:0046578 114 0.039
hexose metabolic process GO:0019318 98 0.039
epithelial cell proliferation GO:0050673 174 0.039
positive regulation of neuron projection development GO:0010976 79 0.039
regulation of protein binding GO:0043393 60 0.039
divalent inorganic cation transport GO:0072511 178 0.039
reproductive behavior GO:0019098 32 0.039
oocyte axis specification GO:0007309 2 0.038
regulation of cytoplasmic transport GO:1903649 112 0.038
neuron projection extension GO:1990138 64 0.038
regulation of extrinsic apoptotic signaling pathway GO:2001236 77 0.038
positive regulation of innate immune response GO:0045089 80 0.038
connective tissue development GO:0061448 179 0.038
regulation of protein transport GO:0051223 163 0.038
cerebellum morphogenesis GO:0021587 42 0.037
response to starvation GO:0042594 65 0.037
regulation of chromatin modification GO:1903308 57 0.037
morphogenesis of embryonic epithelium GO:0016331 159 0.037
cellular response to lipid GO:0071396 145 0.037
purine ribonucleotide biosynthetic process GO:0009152 59 0.037
establishment of protein localization to membrane GO:0090150 54 0.037
regulation of lymphocyte differentiation GO:0045619 107 0.037
cell recognition GO:0008037 83 0.037
regulation of hormone levels GO:0010817 211 0.037
negative regulation of neuron death GO:1901215 98 0.036
purine containing compound catabolic process GO:0072523 213 0.036
b cell activation GO:0042113 161 0.036
smoothened signaling pathway GO:0007224 105 0.036
cyclic nucleotide biosynthetic process GO:0009190 44 0.036
bmp signaling pathway GO:0030509 93 0.036
response to uv GO:0009411 44 0.036
negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 26 0.036
mesonephric epithelium development GO:0072163 94 0.036
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.036
lymphocyte homeostasis GO:0002260 64 0.036
membrane organization GO:0061024 245 0.036
negative regulation of phosphate metabolic process GO:0045936 184 0.036
oogenesis GO:0048477 56 0.036
energy derivation by oxidation of organic compounds GO:0015980 77 0.035
reciprocal meiotic recombination GO:0007131 16 0.035
developmental growth involved in morphogenesis GO:0060560 138 0.035
cartilage development GO:0051216 140 0.035
epidermal growth factor receptor signaling pathway GO:0007173 28 0.035
small gtpase mediated signal transduction GO:0007264 97 0.035
engulfment of apoptotic cell GO:0043652 3 0.035
generation of precursor metabolites and energy GO:0006091 103 0.035
adaptive immune response GO:0002250 155 0.035
regulation of dna templated transcription in response to stress GO:0043620 9 0.035
negative regulation of leukocyte differentiation GO:1902106 51 0.035
receptor mediated endocytosis GO:0006898 51 0.035
regulation of fat cell differentiation GO:0045598 81 0.035
negative regulation of protein maturation GO:1903318 79 0.035
regulation of protein catabolic process GO:0042176 108 0.035
nucleoside phosphate metabolic process GO:0006753 338 0.035
purine containing compound biosynthetic process GO:0072522 70 0.035

Mecp2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.131
disease of anatomical entity DOID:7 0 0.078
nervous system disease DOID:863 0 0.078
central nervous system disease DOID:331 0 0.076
neurodegenerative disease DOID:1289 0 0.076
cancer DOID:162 0 0.068
disease of cellular proliferation DOID:14566 0 0.068
organ system cancer DOID:0050686 0 0.068
cornelia de lange syndrome DOID:11725 0 0.060