Mus musculus

79 known processes

Pik3r3

phosphatidylinositol 3 kinase, regulatory subunit, polypeptide 3 (p55)

(Aliases: p55pik,AA414954)

Pik3r3 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
phosphatidylinositol phosphorylation GO:0046854 23 0.637
regulation of zinc ion transport GO:0071579 2 0.417
lipid phosphorylation GO:0046834 25 0.406
regulation of zinc ion transmembrane transport GO:0071580 2 0.202
glycerophospholipid biosynthetic process GO:0046474 32 0.201
glycerolipid biosynthetic process GO:0045017 50 0.197
negative regulation of zinc ion transmembrane transport GO:0071583 2 0.166
phospholipid biosynthetic process GO:0008654 36 0.155
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.131
transmembrane transport GO:0055085 412 0.123
positive regulation of cellular amine metabolic process GO:0033240 5 0.098
negative regulation of fibroblast apoptotic process GO:2000270 6 0.097
glycerophospholipid metabolic process GO:0006650 71 0.093
organic cyclic compound catabolic process GO:1901361 295 0.087
nucleotide metabolic process GO:0009117 332 0.086
dna modification GO:0006304 50 0.085
regulation of cellular amino acid metabolic process GO:0006521 5 0.085
phosphatidylinositol 3 phosphate biosynthetic process GO:0036092 6 0.081
regulation of cellular amine metabolic process GO:0033238 20 0.075
dna metabolic process GO:0006259 303 0.073
nucleobase containing small molecule metabolic process GO:0055086 352 0.071
cellular amine metabolic process GO:0044106 44 0.069
carbohydrate derivative catabolic process GO:1901136 231 0.068
cellular ketone metabolic process GO:0042180 84 0.068
regulation of dna methylation GO:0044030 12 0.067
synaptic transmission GO:0007268 329 0.067
purine ribonucleoside metabolic process GO:0046128 241 0.067
amine metabolic process GO:0009308 45 0.067
cellular amino acid metabolic process GO:0006520 103 0.067
microtubule based process GO:0007017 236 0.066
cation transmembrane transport GO:0098655 266 0.066
aromatic compound catabolic process GO:0019439 286 0.065
phospholipid metabolic process GO:0006644 87 0.060
transition metal ion transport GO:0000041 38 0.060
regulation of genetic imprinting GO:2000653 5 0.060
inorganic ion transmembrane transport GO:0098660 234 0.059
purine nucleotide catabolic process GO:0006195 211 0.058
organonitrogen compound catabolic process GO:1901565 264 0.058
glycosyl compound metabolic process GO:1901657 246 0.057
regulation of cellular ketone metabolic process GO:0010565 66 0.054
cell substrate adhesion GO:0031589 130 0.052
Mouse
ribonucleoside triphosphate catabolic process GO:0009203 199 0.052
purine nucleoside triphosphate catabolic process GO:0009146 203 0.052
small gtpase mediated signal transduction GO:0007264 97 0.051
ribonucleotide catabolic process GO:0009261 208 0.050
positive regulation of protein modification process GO:0031401 299 0.049
glucose metabolic process GO:0006006 92 0.049
purine ribonucleotide metabolic process GO:0009150 290 0.049
ribonucleotide metabolic process GO:0009259 291 0.047
ribonucleoside catabolic process GO:0042454 206 0.046
glycerolipid metabolic process GO:0046486 122 0.046
regulation of transferase activity GO:0051338 263 0.046
methylation GO:0032259 134 0.044
inorganic cation transmembrane transport GO:0098662 207 0.044
cellular homeostasis GO:0019725 240 0.042
dna alkylation GO:0006305 43 0.042
ribose phosphate metabolic process GO:0019693 291 0.042
organophosphate biosynthetic process GO:0090407 122 0.041
carbohydrate metabolic process GO:0005975 230 0.041
macromolecule catabolic process GO:0009057 281 0.041
ion transmembrane transport GO:0034220 361 0.040
genetic imprinting GO:0071514 27 0.040
neuron death GO:0070997 154 0.040
cellular component assembly involved in morphogenesis GO:0010927 139 0.040
organophosphate catabolic process GO:0046434 232 0.040
lipid biosynthetic process GO:0008610 179 0.040
macromolecule methylation GO:0043414 120 0.039
actin cytoskeleton organization GO:0030036 220 0.039
ribonucleoside metabolic process GO:0009119 245 0.039
cell adhesion GO:0007155 329 0.039
Mouse
gtp catabolic process GO:0006184 143 0.039
negative regulation of zinc ion transport GO:0071582 2 0.038
positive regulation of protein phosphorylation GO:0001934 242 0.038
cognition GO:0050890 149 0.038
germ cell development GO:0007281 185 0.038
regulation of neuron projection development GO:0010975 169 0.038
regulation of translation GO:0006417 71 0.038
cation transport GO:0006812 399 0.038
regulation of organelle organization GO:0033043 289 0.037
ribonucleoside triphosphate metabolic process GO:0009199 220 0.037
regulation of cell projection organization GO:0031344 206 0.037
glycosyl compound catabolic process GO:1901658 206 0.037
cation homeostasis GO:0055080 212 0.037
response to light stimulus GO:0009416 135 0.036
Mouse
purine nucleoside triphosphate metabolic process GO:0009144 226 0.036
nucleoside phosphate metabolic process GO:0006753 338 0.035
muscle cell differentiation GO:0042692 261 0.035
dna methylation GO:0006306 43 0.035
positive regulation of transferase activity GO:0051347 167 0.035
negative regulation of cellular protein metabolic process GO:0032269 247 0.034
protein ubiquitination GO:0016567 171 0.034
cell division GO:0051301 120 0.033
positive regulation of neuron differentiation GO:0045666 141 0.033
homeostasis of number of cells GO:0048872 210 0.032
protein modification by small protein conjugation GO:0032446 187 0.032
purine ribonucleoside catabolic process GO:0046130 205 0.032
purine ribonucleotide catabolic process GO:0009154 208 0.032
response to radiation GO:0009314 165 0.032
Mouse
regulation of cell substrate adhesion GO:0010810 73 0.032
Mouse
modification dependent protein catabolic process GO:0019941 133 0.032
hexose metabolic process GO:0019318 98 0.032
cellular chemical homeostasis GO:0055082 215 0.031
zinc ion transmembrane transport GO:0071577 10 0.031
regulation of nucleoside metabolic process GO:0009118 130 0.031
dna hypomethylation GO:0044028 1 0.031
apoptotic signaling pathway GO:0097190 306 0.031
Mouse
regulation of hydrolase activity GO:0051336 246 0.031
homophilic cell adhesion via plasma membrane adhesion molecules GO:0007156 18 0.031
coagulation GO:0050817 78 0.030
organelle assembly GO:0070925 177 0.030
nucleoside phosphate catabolic process GO:1901292 222 0.030
negative regulation of protein metabolic process GO:0051248 282 0.030
wound healing GO:0042060 157 0.030
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.030
neuron apoptotic process GO:0051402 142 0.029
regulation of transmembrane transport GO:0034762 128 0.029
regulation of cell migration GO:0030334 219 0.029
Mouse
regulation of kinase activity GO:0043549 249 0.029
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.029
immune effector process GO:0002252 321 0.029
negative regulation of cell proliferation GO:0008285 296 0.029
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.029
regulation of cell adhesion GO:0030155 154 0.029
Mouse
peptidyl serine modification GO:0018209 83 0.028
phosphatidylinositol metabolic process GO:0046488 45 0.028
regulation of cell cycle GO:0051726 281 0.028
regulation of apoptotic signaling pathway GO:2001233 197 0.028
rho protein signal transduction GO:0007266 32 0.028
cellular lipid metabolic process GO:0044255 323 0.028
negative regulation of cellular component organization GO:0051129 194 0.028
positive regulation of cellular catabolic process GO:0031331 148 0.028
regulation of metal ion transport GO:0010959 106 0.027
divalent inorganic cation homeostasis GO:0072507 138 0.027
positive regulation of protein kinase activity GO:0045860 144 0.027
actin filament organization GO:0007015 113 0.027
muscle cell development GO:0055001 133 0.027
protein localization to organelle GO:0033365 185 0.027
Mouse
regulation of neuron death GO:1901214 134 0.027
translation GO:0006412 93 0.027
peptidyl amino acid modification GO:0018193 336 0.027
regulation of body fluid levels GO:0050878 162 0.026
response to insulin GO:0032868 100 0.026
cellular protein catabolic process GO:0044257 155 0.026
developmental maturation GO:0021700 193 0.026
guanosine containing compound catabolic process GO:1901069 144 0.026
monosaccharide metabolic process GO:0005996 106 0.026
regulation of ion transmembrane transport GO:0034765 119 0.026
metal ion homeostasis GO:0055065 189 0.026
blood coagulation GO:0007596 76 0.025
learning or memory GO:0007611 148 0.025
protein modification by small protein conjugation or removal GO:0070647 207 0.025
microtubule cytoskeleton organization GO:0000226 157 0.025
regulation of purine nucleotide catabolic process GO:0033121 122 0.025
cilium morphogenesis GO:0060271 102 0.024
purine nucleoside metabolic process GO:0042278 241 0.024
regulation of ras protein signal transduction GO:0046578 114 0.024
compound eye development GO:0048749 1 0.024
muscle tissue development GO:0060537 308 0.024
cell cell adhesion GO:0098609 41 0.024
purine containing compound metabolic process GO:0072521 311 0.024
cell cell adhesion via plasma membrane adhesion molecules GO:0098742 40 0.024
nucleoside metabolic process GO:0009116 246 0.024
regulation of purine nucleotide metabolic process GO:1900542 169 0.024
nucleoside triphosphate metabolic process GO:0009141 230 0.023
regulation of cell motility GO:2000145 236 0.023
Mouse
cellular metal ion homeostasis GO:0006875 151 0.023
regulation of neuron apoptotic process GO:0043523 122 0.023
regulation of protein kinase activity GO:0045859 232 0.023
endomembrane system organization GO:0010256 147 0.022
mitotic cell cycle GO:0000278 195 0.022
purine nucleotide metabolic process GO:0006163 302 0.022
g protein coupled receptor signaling pathway GO:0007186 243 0.022
multicellular organism growth GO:0035264 161 0.022
negative regulation of immune system process GO:0002683 209 0.022
Mouse
platelet activation GO:0030168 40 0.021
b cell activation GO:0042113 161 0.021
Mouse
spermatid differentiation GO:0048515 115 0.021
rac protein signal transduction GO:0016601 13 0.021
heterocycle catabolic process GO:0046700 280 0.021
cellular macromolecule catabolic process GO:0044265 206 0.021
protein complex disassembly GO:0043241 40 0.021
purine containing compound catabolic process GO:0072523 213 0.020
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.020
hypomethylation of cpg island GO:0044029 1 0.020
positive regulation of peptidyl serine phosphorylation GO:0033138 25 0.020
cytokine production GO:0001816 319 0.020
Mouse
ubiquitin dependent protein catabolic process GO:0006511 129 0.020
regulation of cellular catabolic process GO:0031329 242 0.020
positive regulation of cell development GO:0010720 237 0.020
cellular response to lipid GO:0071396 145 0.020
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.020
morphogenesis of embryonic epithelium GO:0016331 159 0.020
oocyte axis specification GO:0007309 2 0.020
spermatid development GO:0007286 108 0.020
exocytosis GO:0006887 121 0.020
lipid modification GO:0030258 65 0.020
regulation of synaptic plasticity GO:0048167 87 0.020
cell type specific apoptotic process GO:0097285 268 0.020
muscle system process GO:0003012 141 0.020
cellular nitrogen compound catabolic process GO:0044270 280 0.019
synapse organization GO:0050808 125 0.019
striated muscle cell development GO:0055002 125 0.019
negative regulation of organelle organization GO:0010639 90 0.019
protein depolymerization GO:0051261 34 0.019
nucleoside triphosphate catabolic process GO:0009143 205 0.019
regulation of cellular component size GO:0032535 121 0.019
Fly
t cell activation GO:0042110 289 0.019
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.019
response to growth factor GO:0070848 198 0.019
neural tube development GO:0021915 160 0.018
cellular ion homeostasis GO:0006873 165 0.018
neuronal action potential GO:0019228 54 0.018
positive regulation of cell death GO:0010942 224 0.018
positive regulation of purine nucleotide catabolic process GO:0033123 88 0.018
regulation of vesicle mediated transport GO:0060627 139 0.018
regulation of cytokine production GO:0001817 266 0.018
Mouse
axonogenesis GO:0007409 274 0.018
nucleotide catabolic process GO:0009166 217 0.018
protein catabolic process GO:0030163 221 0.018
positive regulation of cell projection organization GO:0031346 95 0.018
gland development GO:0048732 330 0.018
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.018
male gamete generation GO:0048232 285 0.018
myotube differentiation GO:0014902 105 0.018
regulation of actin filament based process GO:0032970 99 0.017
positive regulation of cell motility GO:2000147 116 0.017
Mouse
membrane organization GO:0061024 245 0.017
positive regulation of gtpase activity GO:0043547 85 0.017
negative regulation of neuron death GO:1901215 98 0.017
nucleoside catabolic process GO:0009164 206 0.017
negative regulation of cytoskeleton organization GO:0051494 36 0.017
peptidyl serine phosphorylation GO:0018105 74 0.017
positive regulation of kinase activity GO:0033674 155 0.017
lymphocyte differentiation GO:0030098 242 0.017
Mouse
embryonic epithelial tube formation GO:0001838 130 0.017
nitrogen compound transport GO:0071705 271 0.017
carbohydrate derivative biosynthetic process GO:1901137 183 0.017
calcium ion homeostasis GO:0055074 127 0.017
positive regulation of programmed cell death GO:0043068 218 0.017
digestive tract development GO:0048565 190 0.017
intracellular protein transport GO:0006886 204 0.016
Mouse
rap protein signal transduction GO:0032486 3 0.016
purine nucleoside catabolic process GO:0006152 205 0.016
retina development in camera type eye GO:0060041 119 0.016
protein targeting GO:0006605 143 0.016
Mouse
positive regulation of apoptotic process GO:0043065 217 0.016
fat cell differentiation GO:0045444 160 0.016
negative regulation of transmembrane transport GO:0034763 15 0.016
positive regulation of growth GO:0045927 104 0.016
positive regulation of nucleotide catabolic process GO:0030813 88 0.016
macromolecular complex disassembly GO:0032984 43 0.016
regulation of secretion GO:0051046 274 0.015
glucose homeostasis GO:0042593 128 0.015
regulation of proteolysis GO:0030162 164 0.015
cellular response to organonitrogen compound GO:0071417 145 0.015
negative regulation of apoptotic signaling pathway GO:2001234 104 0.015
positive regulation of gtp catabolic process GO:0033126 85 0.015
response to inorganic substance GO:0010035 96 0.015
transmission of nerve impulse GO:0019226 76 0.015
negative regulation of leukocyte differentiation GO:1902106 51 0.015
Mouse
cellular divalent inorganic cation homeostasis GO:0072503 127 0.015
photoreceptor cell morphogenesis GO:0008594 3 0.015
activation of adenylate cyclase activity GO:0007190 4 0.015
negative regulation of neuron apoptotic process GO:0043524 92 0.015
cellular protein complex assembly GO:0043623 116 0.015
pole plasm assembly GO:0007315 2 0.015
regulation of cell size GO:0008361 72 0.015
Fly
chromatin organization GO:0006325 206 0.015
response to peptide hormone GO:0043434 127 0.015
cellular response to hormone stimulus GO:0032870 150 0.015
regulation of peptidyl serine phosphorylation GO:0033135 39 0.015
cellular carbohydrate metabolic process GO:0044262 119 0.015
posttranscriptional regulation of gene expression GO:0010608 155 0.015
cellular protein complex disassembly GO:0043624 36 0.015
engulfment of apoptotic cell GO:0043652 3 0.014
positive regulation of ras gtpase activity GO:0032320 65 0.014
regulation of cytoskeleton organization GO:0051493 122 0.014
t cell differentiation GO:0030217 174 0.014
actin polymerization or depolymerization GO:0008154 54 0.014
protein maturation GO:0051604 176 0.014
regulation of nucleotide metabolic process GO:0006140 169 0.014
morphogenesis of a branching epithelium GO:0061138 193 0.014
neural tube formation GO:0001841 108 0.014
regulation of ion transport GO:0043269 215 0.014
smoothened signaling pathway GO:0007224 105 0.014
negative regulation of cell development GO:0010721 169 0.014
actin filament polymerization GO:0030041 44 0.014
leukocyte differentiation GO:0002521 342 0.014
Mouse
peptidyl tyrosine phosphorylation GO:0018108 143 0.014
organelle fission GO:0048285 170 0.013
regulation of anatomical structure size GO:0090066 178 0.013
Fly
regulation of leukocyte differentiation GO:1902105 159 0.013
Mouse
adult behavior GO:0030534 135 0.013
regulation of cellular component biogenesis GO:0044087 181 0.013
myeloid cell differentiation GO:0030099 233 0.013
Mouse
male genitalia morphogenesis GO:0048808 4 0.013
establishment or maintenance of cytoskeleton polarity GO:0030952 2 0.013
negative regulation of cellular catabolic process GO:0031330 47 0.013
chemotaxis GO:0006935 247 0.013
cellular response to growth factor stimulus GO:0071363 197 0.013
cilium assembly GO:0042384 81 0.013
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.013
epithelial cell proliferation GO:0050673 174 0.013
oocyte construction GO:0007308 2 0.013
positive regulation of nucleoside metabolic process GO:0045979 91 0.013
viral gene expression GO:0019080 3 0.013
negative regulation of protein complex disassembly GO:0043242 22 0.013
wnt signaling pathway GO:0016055 188 0.013
mrna metabolic process GO:0016071 84 0.013
forebrain development GO:0030900 302 0.013
cell growth GO:0016049 130 0.013
regulation of reactive oxygen species metabolic process GO:2000377 40 0.013
stem cell differentiation GO:0048863 268 0.012
negative regulation of synapse assembly GO:0051964 3 0.012
localization within membrane GO:0051668 4 0.012
oogenesis GO:0048477 56 0.012
gastrulation GO:0007369 116 0.012
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.012
epithelial tube formation GO:0072175 130 0.012
regulation of cell growth GO:0001558 91 0.012
myelination GO:0042552 74 0.012
inflammatory response GO:0006954 244 0.012
negative regulation of anoikis GO:2000811 2 0.012
axon ensheathment GO:0008366 76 0.012
learning GO:0007612 98 0.012
regulation of anoikis GO:2000209 2 0.012
purine nucleoside monophosphate metabolic process GO:0009126 81 0.012
regulation of protein complex disassembly GO:0043244 28 0.012
peptide transport GO:0015833 133 0.012
cellular calcium ion homeostasis GO:0006874 119 0.012
positive regulation of intracellular transport GO:0032388 70 0.012
retrograde transport endosome to golgi GO:0042147 2 0.012
transforming growth factor beta receptor signaling pathway GO:0007179 71 0.012
camera type eye development GO:0043010 266 0.012
glycoprotein metabolic process GO:0009100 116 0.012
symbiosis encompassing mutualism through parasitism GO:0044403 83 0.012
nucleocytoplasmic transport GO:0006913 139 0.012
Mouse
microtubule based movement GO:0007018 84 0.012
multicellular organismal signaling GO:0035637 91 0.011
gonad morphogenesis GO:0035262 1 0.011
tube formation GO:0035148 140 0.011
multi multicellular organism process GO:0044706 109 0.011
negative regulation of cell motility GO:2000146 61 0.011
reactive oxygen species metabolic process GO:0072593 84 0.011
cellular response to organic cyclic compound GO:0071407 87 0.011
regulation of multi organism process GO:0043900 111 0.011
regulation of neuronal synaptic plasticity GO:0048168 30 0.011
muscle fiber development GO:0048747 76 0.011
cytoplasmic transport GO:0016482 234 0.011
Mouse
carbohydrate homeostasis GO:0033500 128 0.011
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.011
spermatogenesis GO:0007283 284 0.011
lung development GO:0030324 164 0.011
negative regulation of molecular function GO:0044092 258 0.011
developmental growth involved in morphogenesis GO:0060560 138 0.011
regulation of mitotic cell cycle GO:0007346 126 0.011
tube closure GO:0060606 91 0.011
skeletal muscle organ development GO:0060538 163 0.011
leukocyte mediated immunity GO:0002443 174 0.011
regulation of lymphocyte activation GO:0051249 240 0.011
photoreceptor cell differentiation GO:0046530 52 0.011
pallium development GO:0021543 120 0.011
negative regulation of protein depolymerization GO:1901880 21 0.011
maternal determination of anterior posterior axis embryo GO:0008358 2 0.011
connective tissue development GO:0061448 179 0.011
proteasomal protein catabolic process GO:0010498 98 0.011
renal system development GO:0072001 225 0.011
regulation of protein depolymerization GO:1901879 26 0.011
regulation of t cell activation GO:0050863 170 0.011
regulation of microtubule based process GO:0032886 52 0.011
microtubule based transport GO:0010970 50 0.011
protein kinase b signaling GO:0043491 74 0.011
morphogenesis of a branching structure GO:0001763 203 0.011
dendritic spine organization GO:0097061 26 0.011
sensory perception GO:0007600 245 0.011
primary neural tube formation GO:0014020 95 0.011
blood circulation GO:0008015 195 0.011
skeletal system morphogenesis GO:0048705 203 0.011
positive regulation of cell migration GO:0030335 109 0.011
Mouse
myeloid leukocyte differentiation GO:0002573 119 0.011
Mouse
positive regulation of ubiquitin protein transferase activity GO:0051443 4 0.011
lateral inhibition GO:0046331 1 0.011
negative regulation of ion transport GO:0043271 28 0.011
regulation of fibroblast apoptotic process GO:2000269 8 0.010
male sex differentiation GO:0046661 109 0.010
cyclic nucleotide metabolic process GO:0009187 59 0.010
interspecies interaction between organisms GO:0044419 83 0.010
b cell homeostasis GO:0001782 34 0.010
regulation of striated muscle cell differentiation GO:0051153 81 0.010
regulation of nucleotide catabolic process GO:0030811 122 0.010
regulation of hormone levels GO:0010817 211 0.010
locomotory behavior GO:0007626 195 0.010
inclusion body assembly GO:0070841 3 0.010
respiratory tube development GO:0030323 167 0.010
myosin filament assembly GO:0031034 2 0.010
peptide secretion GO:0002790 114 0.010
fibroblast apoptotic process GO:0044346 9 0.010
ear development GO:0043583 200 0.010
regulation of viral transcription GO:0046782 3 0.010
male anatomical structure morphogenesis GO:0090598 4 0.010
viral transcription GO:0019083 3 0.010
response to nutrient levels GO:0031667 109 0.010
regulation of binding GO:0051098 111 0.010

Pik3r3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
thoracic cancer DOID:5093 0 0.032
cancer DOID:162 0 0.032
disease of cellular proliferation DOID:14566 0 0.032
organ system cancer DOID:0050686 0 0.032
disease of anatomical entity DOID:7 0 0.029
integumentary system disease DOID:16 0 0.029
breast cancer DOID:1612 0 0.021
large intestine cancer DOID:5672 0 0.018
colon cancer DOID:219 0 0.018
gastrointestinal system cancer DOID:3119 0 0.018
intestinal cancer DOID:10155 0 0.018
colorectal cancer DOID:9256 0 0.018
immune system disease DOID:2914 0 0.015
nervous system disease DOID:863 0 0.014
colon carcinoma DOID:1520 0 0.013
central nervous system disease DOID:331 0 0.011