Mus musculus

96 known processes

Iqgap1

IQ motif containing GTPase activating protein 1

(Aliases: mKIAA0051,D7Ertd237e,AA682088,D7Ertd257e)

Iqgap1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
actin cytoskeleton organization GO:0030036 220 0.839
actin filament organization GO:0007015 113 0.639
apical constriction GO:0003383 4 0.627
actin cytoskeleton reorganization GO:0031532 21 0.548
actin filament polymerization GO:0030041 44 0.490
ras protein signal transduction GO:0007265 77 0.474
Mouse
actin filament based movement GO:0030048 23 0.452
regulation of actin filament polymerization GO:0030833 38 0.432
regulation of actin filament length GO:0030832 45 0.414
small gtpase mediated signal transduction GO:0007264 97 0.403
Mouse
regulation of actin cytoskeleton organization GO:0032956 84 0.361
immune effector process GO:0002252 321 0.356
cell adhesion GO:0007155 329 0.347
chemotaxis GO:0006935 247 0.345
regulation of cellular component biogenesis GO:0044087 181 0.339
axonogenesis GO:0007409 274 0.335
microtubule cytoskeleton organization GO:0000226 157 0.333
leukocyte differentiation GO:0002521 342 0.329
wound healing GO:0042060 157 0.318
digestive system development GO:0055123 200 0.304
myeloid leukocyte differentiation GO:0002573 119 0.302
axon guidance GO:0007411 141 0.288
regulation of cell motility GO:2000145 236 0.276
positive regulation of actin filament polymerization GO:0030838 26 0.257
regulation of cell projection assembly GO:0060491 38 0.257
divalent inorganic cation transport GO:0072511 178 0.255
calcium ion transport GO:0006816 159 0.244
cation transport GO:0006812 399 0.243
t cell activation GO:0042110 289 0.239
establishment of organelle localization GO:0051656 122 0.234
negative regulation of molecular function GO:0044092 258 0.229
divalent metal ion transport GO:0070838 172 0.228
regulation of cytoskeleton organization GO:0051493 122 0.218
membrane organization GO:0061024 245 0.217
cellular component assembly involved in morphogenesis GO:0010927 139 0.217
regulation of cell projection organization GO:0031344 206 0.214
amine metabolic process GO:0009308 45 0.214
filopodium assembly GO:0046847 19 0.213
actin polymerization or depolymerization GO:0008154 54 0.213
cellular divalent inorganic cation homeostasis GO:0072503 127 0.212
epithelial cell morphogenesis GO:0003382 41 0.207
myeloid cell differentiation GO:0030099 233 0.205
organelle assembly GO:0070925 177 0.205
cellular protein complex assembly GO:0043623 116 0.203
regulation of t cell activation GO:0050863 170 0.199
organonitrogen compound catabolic process GO:1901565 264 0.198
regulation of cellular amine metabolic process GO:0033238 20 0.196
regulation of anatomical structure size GO:0090066 178 0.194
Mouse
angiogenesis GO:0001525 201 0.192
macromolecule catabolic process GO:0009057 281 0.189
rho protein signal transduction GO:0007266 32 0.188
regulation of actin filament based process GO:0032970 99 0.188
cellular ketone metabolic process GO:0042180 84 0.185
cellular amine metabolic process GO:0044106 44 0.182
osteoclast differentiation GO:0030316 62 0.180
regulation of cell migration GO:0030334 219 0.174
regulation of cell adhesion GO:0030155 154 0.173
ribonucleotide catabolic process GO:0009261 208 0.171
nuclear division GO:0000280 158 0.170
Worm
muscle system process GO:0003012 141 0.167
multicellular organismal homeostasis GO:0048871 164 0.164
purine containing compound catabolic process GO:0072523 213 0.161
negative regulation of protein metabolic process GO:0051248 282 0.154
b cell differentiation GO:0030183 78 0.154
positive regulation of organelle organization GO:0010638 128 0.151
atp catabolic process GO:0006200 55 0.150
plasma membrane organization GO:0007009 90 0.149
negative regulation of cell proliferation GO:0008285 296 0.145
organelle localization GO:0051640 179 0.144
cytokinetic process GO:0032506 2 0.144
purine ribonucleotide metabolic process GO:0009150 290 0.144
regulation of cell shape GO:0008360 39 0.143
regulation of cell cycle process GO:0010564 160 0.142
myeloid leukocyte activation GO:0002274 83 0.141
regulation of organelle organization GO:0033043 289 0.141
leukocyte proliferation GO:0070661 172 0.140
regulation of intracellular transport GO:0032386 159 0.139
digestive tract development GO:0048565 190 0.139
dna metabolic process GO:0006259 303 0.139
positive regulation of protein phosphorylation GO:0001934 242 0.138
regulation of leukocyte differentiation GO:1902105 159 0.137
ion transmembrane transport GO:0034220 361 0.134
single organism cell adhesion GO:0098602 156 0.134
response to endoplasmic reticulum stress GO:0034976 53 0.133
muscle cell development GO:0055001 133 0.128
regulation of calcium ion transport GO:0051924 69 0.125
positive regulation of cell motility GO:2000147 116 0.123
regulation of protein complex assembly GO:0043254 83 0.123
nucleotide metabolic process GO:0009117 332 0.123
blood vessel morphogenesis GO:0048514 285 0.122
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.120
regulation of rho gtpase activity GO:0032319 58 0.117
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.117
regulation of protein localization GO:0032880 231 0.117
regulation of t cell proliferation GO:0042129 92 0.116
gonad development GO:0008406 141 0.116
actomyosin structure organization GO:0031032 56 0.115
cytosolic calcium ion transport GO:0060401 48 0.114
mitotic cell cycle GO:0000278 195 0.113
Mouse
positive regulation of kinase activity GO:0033674 155 0.112
t cell proliferation GO:0042098 120 0.112
regulation of vesicle mediated transport GO:0060627 139 0.112
positive regulation of cytoskeleton organization GO:0051495 49 0.109
epithelial cell development GO:0002064 159 0.108
regulation of metal ion transport GO:0010959 106 0.107
cation homeostasis GO:0055080 212 0.106
cellularization GO:0007349 1 0.106
maintenance of location GO:0051235 89 0.105
Worm
transmembrane transport GO:0055085 412 0.104
regulation of ion transport GO:0043269 215 0.104
neuron migration GO:0001764 122 0.102
organophosphate catabolic process GO:0046434 232 0.102
regulation of protein kinase activity GO:0045859 232 0.101
coagulation GO:0050817 78 0.101
regulation of lymphocyte activation GO:0051249 240 0.100
regulation of cellular ketone metabolic process GO:0010565 66 0.100
neuron projection guidance GO:0097485 141 0.100
ribonucleoside monophosphate metabolic process GO:0009161 80 0.100
urogenital system development GO:0001655 261 0.100
cytokine mediated signaling pathway GO:0019221 115 0.100
regulation of system process GO:0044057 200 0.099
response to acid chemical GO:0001101 111 0.098
regulation of body fluid levels GO:0050878 162 0.097
germ cell development GO:0007281 185 0.097
nucleoside metabolic process GO:0009116 246 0.096
divalent inorganic cation homeostasis GO:0072507 138 0.095
modification dependent protein catabolic process GO:0019941 133 0.094
mapk cascade GO:0000165 281 0.094
Mouse
microtubule based process GO:0007017 236 0.093
cellular ion homeostasis GO:0006873 165 0.093
cellular amino acid metabolic process GO:0006520 103 0.092
spindle localization GO:0051653 22 0.091
nucleotide catabolic process GO:0009166 217 0.091
muscle cell differentiation GO:0042692 261 0.091
organic anion transport GO:0015711 137 0.091
development of primary sexual characteristics GO:0045137 143 0.090
cellular homeostasis GO:0019725 240 0.090
single organismal cell cell adhesion GO:0016337 131 0.090
carbohydrate derivative catabolic process GO:1901136 231 0.089
leukocyte cell cell adhesion GO:0007159 14 0.089
anion transport GO:0006820 177 0.089
mitotic cell cycle process GO:1903047 159 0.088
Mouse
positive regulation of cell migration GO:0030335 109 0.088
regulation of cell cycle GO:0051726 281 0.088
ribonucleoside metabolic process GO:0009119 245 0.087
organic hydroxy compound metabolic process GO:1901615 203 0.087
multi multicellular organism process GO:0044706 109 0.086
positive regulation of rho gtpase activity GO:0032321 41 0.086
blood coagulation GO:0007596 76 0.085
negative regulation of phosphate metabolic process GO:0045936 184 0.085
epidermis development GO:0008544 187 0.085
regulation of homeostatic process GO:0032844 182 0.084
ribonucleoside triphosphate metabolic process GO:0009199 220 0.084
regulation of kinase activity GO:0043549 249 0.084
regulation of mitotic cell cycle GO:0007346 126 0.084
ameboidal type cell migration GO:0001667 128 0.083
cellular nitrogen compound catabolic process GO:0044270 280 0.083
negative regulation of protein phosphorylation GO:0001933 126 0.083
response to inorganic substance GO:0010035 96 0.082
Human
glycosyl compound metabolic process GO:1901657 246 0.082
organic cyclic compound catabolic process GO:1901361 295 0.082
regulation of cellular component size GO:0032535 121 0.082
Mouse
regulation of ras protein signal transduction GO:0046578 114 0.082
endomembrane system organization GO:0010256 147 0.082
apoptotic signaling pathway GO:0097190 306 0.082
negative regulation of homeostatic process GO:0032845 71 0.081
fertilization GO:0009566 127 0.081
positive regulation of gtpase activity GO:0043547 85 0.081
camera type eye development GO:0043010 266 0.080
purine nucleotide catabolic process GO:0006195 211 0.079
negative regulation of cellular amine metabolic process GO:0033239 1 0.079
nucleoside phosphate catabolic process GO:1901292 222 0.079
regulation of cell activation GO:0050865 289 0.078
establishment or maintenance of cell polarity GO:0007163 86 0.078
alpha beta t cell activation GO:0046631 91 0.078
cell cell junction organization GO:0045216 72 0.078
purine nucleoside metabolic process GO:0042278 241 0.078
negative regulation of apoptotic signaling pathway GO:2001234 104 0.077
regulation of response to wounding GO:1903034 189 0.077
purine nucleoside triphosphate catabolic process GO:0009146 203 0.077
nucleobase containing small molecule metabolic process GO:0055086 352 0.077
cellular response to organonitrogen compound GO:0071417 145 0.077
exocytosis GO:0006887 121 0.077
response to organonitrogen compound GO:0010243 246 0.076
nucleus localization GO:0051647 20 0.076
protein localization to organelle GO:0033365 185 0.076
regulation of protein transport GO:0051223 163 0.076
extracellular structure organization GO:0043062 148 0.076
gastrulation GO:0007369 116 0.075
regulation of embryonic development GO:0045995 71 0.075
oocyte construction GO:0007308 2 0.075
leukocyte migration GO:0050900 124 0.075
positive regulation of protein modification process GO:0031401 299 0.074
protein catabolic process GO:0030163 221 0.074
inorganic ion transmembrane transport GO:0098660 234 0.074
calcium ion homeostasis GO:0055074 127 0.074
regulation of membrane potential GO:0042391 192 0.074
purine ribonucleoside metabolic process GO:0046128 241 0.073
fibrinolysis GO:0042730 3 0.073
regulation of leukocyte proliferation GO:0070663 121 0.073
retina development in camera type eye GO:0060041 119 0.073
t cell differentiation GO:0030217 174 0.072
kidney development GO:0001822 213 0.072
purine nucleotide metabolic process GO:0006163 302 0.072
cellular chemical homeostasis GO:0055082 215 0.072
positive regulation of cellular component biogenesis GO:0044089 94 0.072
myosin filament assembly GO:0031034 2 0.072
cellular calcium ion homeostasis GO:0006874 119 0.072
regulation of transferase activity GO:0051338 263 0.071
positive regulation of cell activation GO:0050867 158 0.071
developmental maturation GO:0021700 193 0.071
purine containing compound metabolic process GO:0072521 311 0.071
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.070
purine nucleoside triphosphate metabolic process GO:0009144 226 0.070
purine nucleoside monophosphate catabolic process GO:0009128 58 0.070
regulation of actin polymerization or depolymerization GO:0008064 45 0.070
positive regulation of leukocyte differentiation GO:1902107 86 0.070
lymphocyte differentiation GO:0030098 242 0.070
regulation of neuron differentiation GO:0045664 281 0.070
positive regulation of homeostatic process GO:0032846 64 0.069
regulation of lymphocyte differentiation GO:0045619 107 0.068
ribonucleotide metabolic process GO:0009259 291 0.068
tissue remodeling GO:0048771 102 0.068
cellular protein catabolic process GO:0044257 155 0.068
regulation of hydrolase activity GO:0051336 246 0.067
regulation of endocytosis GO:0030100 69 0.067
myeloid cell homeostasis GO:0002262 114 0.067
ribose phosphate metabolic process GO:0019693 291 0.067
microglia differentiation GO:0014004 2 0.067
glial cell differentiation GO:0010001 131 0.066
positive regulation of protein kinase activity GO:0045860 144 0.066
mitotic nuclear division GO:0007067 48 0.066
response to organic cyclic compound GO:0014070 198 0.066
nucleoside monophosphate metabolic process GO:0009123 85 0.065
calcium ion transport into cytosol GO:0060402 48 0.065
regulation of purine nucleotide catabolic process GO:0033121 122 0.065
engulfment of apoptotic cell GO:0043652 3 0.065
regulation of mapk cascade GO:0043408 248 0.064
Mouse
response to oxidative stress GO:0006979 123 0.063
regionalization GO:0003002 337 0.063
cell substrate adhesion GO:0031589 130 0.062
protein polymerization GO:0051258 57 0.061
ribonucleoside triphosphate catabolic process GO:0009203 199 0.061
negative regulation of cellular component organization GO:0051129 194 0.060
regulation of cellular amino acid metabolic process GO:0006521 5 0.060
regulation of lymphocyte proliferation GO:0050670 117 0.060
modification dependent macromolecule catabolic process GO:0043632 133 0.060
synaptic transmission GO:0007268 329 0.059
positive regulation of programmed cell death GO:0043068 218 0.059
purine ribonucleoside monophosphate catabolic process GO:0009169 57 0.059
purine nucleoside catabolic process GO:0006152 205 0.059
actin mediated cell contraction GO:0070252 15 0.059
homeostasis of number of cells GO:0048872 210 0.058
endocytosis GO:0006897 168 0.058
striated muscle cell development GO:0055002 125 0.058
renal system development GO:0072001 225 0.058
blood circulation GO:0008015 195 0.057
inflammatory response GO:0006954 244 0.057
regulation of microvillus organization GO:0032530 3 0.057
leukocyte mediated immunity GO:0002443 174 0.056
regulation of calcium ion transport into cytosol GO:0010522 31 0.056
positive regulation of t cell activation GO:0050870 101 0.056
nucleoside triphosphate metabolic process GO:0009141 230 0.055
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.055
Human Mouse
skin development GO:0043588 220 0.055
gtp metabolic process GO:0046039 144 0.055
tissue homeostasis GO:0001894 115 0.055
positive regulation of cell development GO:0010720 237 0.054
spermatid development GO:0007286 108 0.054
positive regulation of protein complex assembly GO:0031334 45 0.054
protein secretion GO:0009306 111 0.054
ossification GO:0001503 216 0.053
circulatory system process GO:0003013 197 0.053
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.053
spermatid differentiation GO:0048515 115 0.053
regulation of cellular catabolic process GO:0031329 242 0.052
guanosine containing compound catabolic process GO:1901069 144 0.052
positive regulation of transferase activity GO:0051347 167 0.051
regulation of nucleotide metabolic process GO:0006140 169 0.051
mitotic cytokinesis GO:0000281 4 0.051
positive regulation of lymphocyte activation GO:0051251 140 0.050
regulation of ras gtpase activity GO:0032318 88 0.050
peptidyl amino acid modification GO:0018193 336 0.050
regulation of neuron projection development GO:0010975 169 0.050
cognition GO:0050890 149 0.050
positive regulation of ras gtpase activity GO:0032320 65 0.050
spermatogenesis GO:0007283 284 0.050
sequestering of metal ion GO:0051238 19 0.049
aromatic compound catabolic process GO:0019439 286 0.049
platelet derived growth factor receptor signaling pathway GO:0048008 32 0.049
genitalia development GO:0048806 37 0.049
forebrain development GO:0030900 302 0.049
cell junction organization GO:0034330 77 0.049
cell division GO:0051301 120 0.049
cellular metal ion homeostasis GO:0006875 151 0.048
atp metabolic process GO:0046034 75 0.048
odontogenesis of dentin containing tooth GO:0042475 66 0.047
regulation of apoptotic signaling pathway GO:2001233 197 0.047
glycosyl compound catabolic process GO:1901658 206 0.047
anatomical structure homeostasis GO:0060249 145 0.047
metal ion homeostasis GO:0055065 189 0.047
nucleoside catabolic process GO:0009164 206 0.047
actin filament bundle assembly GO:0051017 40 0.047
sensory perception of mechanical stimulus GO:0050954 107 0.046
substrate dependent cell migration cell extension GO:0006930 4 0.046
dendrite development GO:0016358 115 0.046
extrinsic apoptotic signaling pathway GO:0097191 126 0.046
regulation of actin nucleation GO:0051125 4 0.046
regulation of neural precursor cell proliferation GO:2000177 70 0.045
leukocyte activation involved in immune response GO:0002366 126 0.045
neural precursor cell proliferation GO:0061351 121 0.045
learning or memory GO:0007611 148 0.045
negative regulation of phosphorylation GO:0042326 166 0.045
membrane tubulation GO:0097320 4 0.045
establishment of protein localization to membrane GO:0090150 54 0.045
organ regeneration GO:0031100 2 0.045
stem cell differentiation GO:0048863 268 0.044
regulation of secretion by cell GO:1903530 249 0.044
skeletal muscle organ development GO:0060538 163 0.044
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.044
regulation of rho protein signal transduction GO:0035023 71 0.044
response to growth factor GO:0070848 198 0.043
intracellular protein transport GO:0006886 204 0.043
oocyte anterior posterior axis specification GO:0007314 2 0.043
ubiquitin dependent protein catabolic process GO:0006511 129 0.043
cell growth GO:0016049 130 0.043
Human
ribonucleoside monophosphate catabolic process GO:0009158 57 0.043
digestive tract morphogenesis GO:0048546 147 0.043
cellular response to growth factor stimulus GO:0071363 197 0.043
positive regulation of gtp catabolic process GO:0033126 85 0.043
male gamete generation GO:0048232 285 0.043
regulation of nucleotide catabolic process GO:0030811 122 0.043
cytoplasmic transport GO:0016482 234 0.042
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.042
multi organism reproductive behavior GO:0044705 29 0.042
neuron projection extension GO:1990138 64 0.042
Human
stem cell development GO:0048864 219 0.042
myeloid leukocyte migration GO:0097529 57 0.042
regulation of microtubule based process GO:0032886 52 0.042
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.041
embryonic placenta development GO:0001892 98 0.041
alpha beta t cell differentiation GO:0046632 69 0.041
myofibril assembly GO:0030239 34 0.041
transforming growth factor beta receptor signaling pathway GO:0007179 71 0.041
cellular response to hormone stimulus GO:0032870 150 0.041
sensory organ morphogenesis GO:0090596 242 0.041
bone resorption GO:0045453 38 0.041
regulation of ossification GO:0030278 112 0.041
cellular response to acid chemical GO:0071229 68 0.041
purine ribonucleoside catabolic process GO:0046130 205 0.041
cation transmembrane transport GO:0098655 266 0.041
establishment of spindle localization GO:0051293 19 0.041
phenol containing compound metabolic process GO:0018958 60 0.040
ribonucleoside catabolic process GO:0042454 206 0.040
cytokinesis GO:0000910 17 0.040
mitotic sister chromatid segregation GO:0000070 14 0.040
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.040
negative regulation of cell development GO:0010721 169 0.040
neuron recognition GO:0008038 25 0.040
regulation of establishment of protein localization GO:0070201 181 0.040
developmental growth involved in morphogenesis GO:0060560 138 0.040
Human
negative regulation of blood vessel endothelial cell migration GO:0043537 3 0.040
regulation of cell cycle phase transition GO:1901987 77 0.040
receptor mediated endocytosis GO:0006898 51 0.039
regulation of purine nucleotide metabolic process GO:1900542 169 0.039
positive regulation of vesicle fusion GO:0031340 2 0.039
regulation of cytoplasmic transport GO:1903649 112 0.039
positive regulation of cell death GO:0010942 224 0.039
gland development GO:0048732 330 0.039
Mouse
muscle tissue development GO:0060537 308 0.038
regulation of filopodium assembly GO:0051489 13 0.038
multicellular organism growth GO:0035264 161 0.038
sequestering of calcium ion GO:0051208 18 0.038
nucleoside phosphate metabolic process GO:0006753 338 0.038
myosin filament organization GO:0031033 3 0.038
locomotory behavior GO:0007626 195 0.038
posttranscriptional regulation of gene expression GO:0010608 155 0.038
inorganic cation transmembrane transport GO:0098662 207 0.038
organic acid transport GO:0015849 101 0.038
lipid transport GO:0006869 98 0.037
positive regulation of cell cycle GO:0045787 92 0.037
proteasomal protein catabolic process GO:0010498 98 0.037
lamellipodium organization GO:0097581 29 0.037
jnk cascade GO:0007254 72 0.037
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 45 0.037
regulation of stress activated mapk cascade GO:0032872 69 0.037
cell activation involved in immune response GO:0002263 126 0.037
positive regulation of map kinase activity GO:0043406 84 0.037
Mouse
positive regulation of t cell proliferation GO:0042102 52 0.036
regulation of wound healing GO:0061041 40 0.036
protein processing GO:0016485 163 0.036
activation of immune response GO:0002253 138 0.036
striated muscle myosin thick filament assembly GO:0071688 1 0.036
regulation of mitotic cell cycle phase transition GO:1901990 73 0.036
leukocyte apoptotic process GO:0071887 71 0.036
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.036
nucleoside triphosphate catabolic process GO:0009143 205 0.036
muscle contraction GO:0006936 101 0.036
cell migration involved in gastrulation GO:0042074 13 0.035
meiotic cell cycle process GO:1903046 77 0.035
hemostasis GO:0007599 78 0.035
negative regulation of intracellular signal transduction GO:1902532 167 0.035
sensory perception of sound GO:0007605 97 0.035
cell junction assembly GO:0034329 52 0.035
regulation of neutrophil apoptotic process GO:0033029 1 0.035
epithelial tube morphogenesis GO:0060562 303 0.035
immunoglobulin mediated immune response GO:0016064 69 0.035
response to oxygen levels GO:0070482 62 0.034
leukocyte chemotaxis GO:0030595 69 0.034
sphingolipid biosynthetic process GO:0030148 26 0.034
regulation of proteolysis GO:0030162 164 0.034
response to metal ion GO:0010038 47 0.034
Human
purine ribonucleotide catabolic process GO:0009154 208 0.034
positive regulation of calcium ion transport GO:0051928 27 0.034
cell matrix adhesion GO:0007160 68 0.034
positive regulation of leukocyte proliferation GO:0070665 73 0.034
endoderm development GO:0007492 45 0.034
t cell receptor signaling pathway GO:0050852 46 0.034
negative regulation of protein modification process GO:0031400 163 0.034
positive regulation of cell morphogenesis involved in differentiation GO:0010770 72 0.034
cellular response to organic cyclic compound GO:0071407 87 0.034
regulation of muscle system process GO:0090257 80 0.034
body morphogenesis GO:0010171 45 0.034
regulation of substrate adhesion dependent cell spreading GO:1900024 12 0.033
positive regulation of ion transport GO:0043270 65 0.033
lipid localization GO:0010876 126 0.033
Worm
respiratory tube development GO:0030323 167 0.033
regulation of extrinsic apoptotic signaling pathway GO:2001236 77 0.033
regulation of map kinase activity GO:0043405 120 0.032
Mouse
response to transforming growth factor beta GO:0071559 88 0.032
positive regulation of cell cycle process GO:0090068 61 0.032
sarcomere organization GO:0045214 24 0.032
ovarian follicle development GO:0001541 40 0.032
striated muscle tissue development GO:0014706 293 0.032
negative regulation of nervous system development GO:0051961 156 0.032
positive regulation of purine nucleotide catabolic process GO:0033123 88 0.032
axon ensheathment GO:0008366 76 0.032
sensory perception GO:0007600 245 0.032
positive regulation of apoptotic process GO:0043065 217 0.031
cellular response to inorganic substance GO:0071241 37 0.031
Human
terminal button organization GO:0072553 3 0.031
heterocycle catabolic process GO:0046700 280 0.031
asymmetric stem cell division GO:0098722 3 0.031
cell recognition GO:0008037 83 0.031
meiotic cell cycle GO:0051321 122 0.031
Worm
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.031
regulation of interleukin 8 production GO:0032677 3 0.031
regulation of cell division GO:0051302 76 0.031
skeletal system development GO:0001501 356 0.030
release of sequestered calcium ion into cytosol GO:0051209 42 0.030
nucleoside monophosphate catabolic process GO:0009125 59 0.030
lateral line system development GO:0048925 1 0.030
interleukin 8 production GO:0032637 4 0.030
cellular response to cytokine stimulus GO:0071345 189 0.030
regulation of microvillus assembly GO:0032534 3 0.030
positive regulation of lymphocyte proliferation GO:0050671 70 0.030
positive regulation of cytosolic calcium ion concentration GO:0007204 65 0.030
regulation of osteoclast differentiation GO:0045670 36 0.030
regulation of osteoblast differentiation GO:0045667 67 0.030
carboxylic acid transport GO:0046942 100 0.029
regulation of nucleoside metabolic process GO:0009118 130 0.029
protein modification by small protein conjugation GO:0032446 187 0.029
negative regulation of phosphorus metabolic process GO:0010563 184 0.029
immune response regulating cell surface receptor signaling pathway GO:0002768 80 0.029
multicellular organismal reproductive behavior GO:0033057 23 0.029
establishment of lymphocyte polarity GO:0001767 2 0.029
negative regulation of cellular protein metabolic process GO:0032269 247 0.029
branching morphogenesis of an epithelial tube GO:0048754 159 0.028
regulation of protein processing GO:0070613 96 0.028
negative regulation of organelle organization GO:0010639 90 0.028
single fertilization GO:0007338 82 0.028
protein localization to membrane GO:0072657 108 0.028
positive regulation of cellular catabolic process GO:0031331 148 0.028
transmission of nerve impulse GO:0019226 76 0.028
lymphocyte proliferation GO:0046651 164 0.028
purine nucleoside monophosphate metabolic process GO:0009126 81 0.028
positive regulation of vasoconstriction GO:0045907 4 0.027
guanosine containing compound metabolic process GO:1901068 144 0.027
regulation of antigen receptor mediated signaling pathway GO:0050854 29 0.027
regulation of blood coagulation GO:0030193 28 0.027
photoreceptor cell development GO:0042461 40 0.027
organonitrogen compound biosynthetic process GO:1901566 192 0.027
positive regulation of nucleotide metabolic process GO:0045981 114 0.027
regulation of clathrin mediated endocytosis GO:2000369 4 0.027
positive regulation of hydrolase activity GO:0051345 148 0.027
male sex differentiation GO:0046661 109 0.027
sphingolipid metabolic process GO:0006665 45 0.027
hepaticobiliary system development GO:0061008 67 0.027
positive regulation of glial cell proliferation GO:0060252 4 0.027
regulation of leukocyte apoptotic process GO:2000106 56 0.027
regulation of secretion GO:0051046 274 0.026

Iqgap1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.089
nervous system disease DOID:863 0 0.089
sensory system disease DOID:0050155 0 0.068
auditory system disease DOID:2742 0 0.051
nonsyndromic deafness DOID:0050563 0 0.051
cancer DOID:162 0 0.031
disease of cellular proliferation DOID:14566 0 0.031
organ system cancer DOID:0050686 0 0.031