Mus musculus

0 known processes

H2-Ob

histocompatibility 2, O region beta locus

(Aliases: A-beta-2,H2-IAb2,H-2I,A-beta2,H2-Ab,H-2Ab,H2-Ab2,Ob,H-2Ob)

H2-Ob biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
antigen processing and presentation GO:0019882 47 0.482
Mouse
innate immune response GO:0045087 157 0.458
Mouse
negative regulation of eosinophil degranulation GO:0043310 1 0.374
regulation of lymphocyte activation GO:0051249 240 0.357
eosinophil activation involved in immune response GO:0002278 1 0.345
positive regulation of t cell costimulation GO:2000525 2 0.326
regulation of cell activation GO:0050865 289 0.321
monocyte extravasation GO:0035696 2 0.317
lymphocyte proliferation GO:0046651 164 0.317
positive regulation of hematopoietic stem cell migration GO:2000473 1 0.310
positive regulation of dendritic cell chemotaxis GO:2000510 1 0.306
t cell activation GO:0042110 289 0.300
eosinophil activation GO:0043307 1 0.293
cytokine production GO:0001816 319 0.291
positive regulation of t cell receptor signaling pathway GO:0050862 4 0.280
cytokine biosynthetic process GO:0042089 68 0.270
positive regulation of immunological synapse formation GO:2000522 1 0.259
regulation of eosinophil degranulation GO:0043309 1 0.257
helper t cell chemotaxis GO:0035704 1 0.254
regulation of immunological synapse formation GO:2000520 2 0.244
regulation of t cell costimulation GO:2000523 2 0.237
immune effector process GO:0002252 321 0.230
t cell extravasation GO:0072683 4 0.230
leukocyte proliferation GO:0070661 172 0.227
regulation of lymphocyte proliferation GO:0050670 117 0.223
positive regulation of cd8 positive alpha beta t cell extravasation GO:2000451 2 0.211
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 87 0.202
regulation of adaptive immune response GO:0002819 90 0.194
regulation of leukocyte proliferation GO:0070663 121 0.183
inflammatory response GO:0006954 244 0.181
myeloid leukocyte activation GO:0002274 83 0.178
negative regulation of immune system process GO:0002683 209 0.177
microglial cell activation involved in immune response GO:0002282 1 0.174
cation transport GO:0006812 399 0.162
positive regulation of cytokine production GO:0001819 174 0.159
adaptive immune response GO:0002250 155 0.150
hematopoietic stem cell migration GO:0035701 1 0.145
tumor necrosis factor superfamily cytokine production GO:0071706 51 0.144
cd8 positive alpha beta t cell extravasation GO:0035697 3 0.142
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.142
multicellular organismal signaling GO:0035637 91 0.139
regulation of immune complex clearance by monocytes and macrophages GO:0090264 2 0.137
regulation of cd8 positive alpha beta t cell extravasation GO:2000449 3 0.137
alpha beta t cell activation GO:0046631 91 0.135
antigen processing and presentation of peptide antigen GO:0048002 29 0.132
Mouse
t cell differentiation GO:0030217 174 0.132
antigen processing and presentation of peptide antigen via mhc class ii GO:0002495 17 0.130
Mouse
immune response activating signal transduction GO:0002757 116 0.130
regulation of monocyte extravasation GO:2000437 2 0.126
leukocyte differentiation GO:0002521 342 0.123
immune complex clearance GO:0002434 2 0.122
antigen processing and presentation of exogenous peptide antigen GO:0002478 21 0.119
Mouse
positive regulation of monocyte extravasation GO:2000439 1 0.117
positive regulation of tumor necrosis factor superfamily cytokine production GO:1903557 31 0.115
lymphocyte differentiation GO:0030098 242 0.114
b cell mediated immunity GO:0019724 71 0.114
regulation of t cell extravasation GO:2000407 3 0.114
cellular homeostasis GO:0019725 240 0.113
immune complex clearance by monocytes and macrophages GO:0002436 2 0.113
immune response activating cell surface receptor signaling pathway GO:0002429 72 0.113
humoral immune response GO:0006959 57 0.112
eosinophil degranulation GO:0043308 1 0.110
positive regulation of cytokine biosynthetic process GO:0042108 40 0.109
eosinophil mediated immunity GO:0002447 1 0.105
positive regulation of lymphocyte activation GO:0051251 140 0.103
cellular chemical homeostasis GO:0055082 215 0.103
cell recognition GO:0008037 83 0.103
regulation of antigen processing and presentation GO:0002577 10 0.101
positive regulation of t cell extravasation GO:2000409 2 0.101
regulation of cytokine production GO:0001817 266 0.099
negative regulation of vasculature development GO:1901343 26 0.099
regulation of defense response GO:0031347 233 0.095
divalent inorganic cation transport GO:0072511 178 0.095
regulation of tumor necrosis factor superfamily cytokine production GO:1903555 50 0.095
regulation of t cell activation GO:0050863 170 0.094
chemokine mediated signaling pathway GO:0070098 17 0.094
blood vessel morphogenesis GO:0048514 285 0.094
antigen processing and presentation of exogenous antigen GO:0019884 26 0.094
Mouse
sequestering of calcium ion GO:0051208 18 0.093
carbohydrate derivative biosynthetic process GO:1901137 183 0.093
positive regulation of t cell activation GO:0050870 101 0.090
immune response regulating cell surface receptor signaling pathway GO:0002768 80 0.090
positive regulation of glycoprotein biosynthetic process involved in immunological synapse formation GO:2000526 1 0.090
g protein coupled receptor signaling pathway GO:0007186 243 0.089
negative regulation of cell activation GO:0050866 111 0.088
antigen receptor mediated signaling pathway GO:0050851 64 0.087
positive regulation of cell activation GO:0050867 158 0.086
interleukin 2 production GO:0032623 33 0.086
positive regulation of adaptive immune response GO:0002821 61 0.083
negative regulation of defense response GO:0031348 77 0.083
negative regulation of blood vessel morphogenesis GO:2000181 25 0.083
interleukin 12 secretion GO:0072610 3 0.083
regulation of dendritic cell chemotaxis GO:2000508 1 0.083
maintenance of location GO:0051235 89 0.081
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 61 0.080
cell killing GO:0001906 67 0.079
negative regulation of homeostatic process GO:0032845 71 0.075
t cell differentiation in thymus GO:0033077 77 0.074
cation homeostasis GO:0055080 212 0.072
negative regulation of macrophage apoptotic process GO:2000110 3 0.072
regulation of homeostatic process GO:0032844 182 0.071
regulation of cytokine biosynthetic process GO:0042035 59 0.070
negative regulation of immune effector process GO:0002698 55 0.069
regulation of tumor necrosis factor biosynthetic process GO:0042534 10 0.069
regulation of leukocyte mediated immunity GO:0002703 104 0.068
lymphocyte mediated immunity GO:0002449 139 0.067
tumor necrosis factor biosynthetic process GO:0042533 10 0.067
t cell proliferation GO:0042098 120 0.066
tumor necrosis factor production GO:0032640 50 0.066
positive regulation of lymphocyte proliferation GO:0050671 70 0.065
macrophage activation GO:0042116 27 0.064
activation of immune response GO:0002253 138 0.064
glycoprotein biosynthetic process GO:0009101 89 0.063
regulation of tumor necrosis factor production GO:0032680 49 0.063
positive regulation of inflammatory response GO:0050729 47 0.062
regulation of apoptotic signaling pathway GO:2001233 197 0.061
negative thymic t cell selection GO:0045060 12 0.060
cell adhesion GO:0007155 329 0.060
cellular calcium ion homeostasis GO:0006874 119 0.059
regulation of leukocyte differentiation GO:1902105 159 0.057
cellular lipid metabolic process GO:0044255 323 0.056
sequestering of metal ion GO:0051238 19 0.056
muscle tissue development GO:0060537 308 0.055
response to interferon gamma GO:0034341 34 0.055
Mouse
positive regulation of cell development GO:0010720 237 0.055
rho protein signal transduction GO:0007266 32 0.054
immunoglobulin mediated immune response GO:0016064 69 0.054
membrane organization GO:0061024 245 0.054
metal ion homeostasis GO:0055065 189 0.053
negative regulation of angiogenesis GO:0016525 25 0.053
regulation of inflammatory response GO:0050727 147 0.053
acute inflammatory response GO:0002526 41 0.052
neuron migration GO:0001764 122 0.052
regulation of hematopoietic stem cell migration GO:2000471 1 0.052
regulation of monocyte chemotaxis GO:0090025 3 0.052
thymic t cell selection GO:0045061 22 0.052
immune response regulating signaling pathway GO:0002764 125 0.051
regulation of interleukin 2 production GO:0032663 28 0.050
myeloid cell differentiation GO:0030099 233 0.050
cellular amino acid metabolic process GO:0006520 103 0.050
leukocyte chemotaxis GO:0030595 69 0.050
response to molecule of bacterial origin GO:0002237 143 0.049
cytoplasmic transport GO:0016482 234 0.049
regulation of ion homeostasis GO:2000021 64 0.049
regulation of phospholipase c activity GO:1900274 3 0.048
cell activation involved in immune response GO:0002263 126 0.048
cellular metal ion homeostasis GO:0006875 151 0.048
cellular divalent inorganic cation homeostasis GO:0072503 127 0.048
positive regulation of immune effector process GO:0002699 107 0.047
cell cell recognition GO:0009988 44 0.047
regulation of angiogenesis GO:0045765 81 0.047
t helper 1 type immune response GO:0042088 25 0.046
divalent inorganic cation homeostasis GO:0072507 138 0.046
regulation of membrane potential GO:0042391 192 0.046
calcium ion homeostasis GO:0055074 127 0.046
cytokine metabolic process GO:0042107 71 0.046
glycoprotein metabolic process GO:0009100 116 0.046
regulation of protein localization GO:0032880 231 0.046
regulation of cell adhesion GO:0030155 154 0.045
b cell proliferation GO:0042100 53 0.045
negative regulation of cell proliferation GO:0008285 296 0.044
epithelial tube morphogenesis GO:0060562 303 0.044
microglial cell activation GO:0001774 3 0.044
t helper 17 cell chemotaxis GO:0035705 1 0.043
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.043
ensheathment of neurons GO:0007272 76 0.042
leukocyte migration GO:0050900 124 0.042
branching morphogenesis of an epithelial tube GO:0048754 159 0.042
regulation of establishment of protein localization GO:0070201 181 0.042
cellular response to biotic stimulus GO:0071216 92 0.042
sensory perception of pain GO:0019233 47 0.042
leukocyte activation involved in immune response GO:0002366 126 0.042
mapk cascade GO:0000165 281 0.041
apoptotic signaling pathway GO:0097190 306 0.041
myeloid cell activation involved in immune response GO:0002275 34 0.041
granulocyte chemotaxis GO:0071621 39 0.041
regulation of secretion by cell GO:1903530 249 0.041
angiogenesis GO:0001525 201 0.040
leukocyte apoptotic process GO:0071887 71 0.040
negative regulation of protein metabolic process GO:0051248 282 0.039
positive regulation of mapk cascade GO:0043410 170 0.039
positive regulation of immune complex clearance by monocytes and macrophages GO:0090265 2 0.039
positive regulation of protein modification process GO:0031401 299 0.039
oligodendrocyte differentiation GO:0048709 53 0.039
regulation of lymphocyte mediated immunity GO:0002706 84 0.039
myeloid cell apoptotic process GO:0033028 22 0.039
positive regulation of protein phosphorylation GO:0001934 242 0.039
natural killer cell mediated immunity GO:0002228 29 0.039
negative regulation of exocytosis GO:0045920 12 0.038
regulation of endocytosis GO:0030100 69 0.038
positive regulation of cell migration GO:0030335 109 0.038
regulation of cellular component size GO:0032535 121 0.038
regulation of alpha beta t cell activation GO:0046634 53 0.038
transmission of nerve impulse GO:0019226 76 0.037
carbohydrate homeostasis GO:0033500 128 0.037
regulation of vesicle mediated transport GO:0060627 139 0.037
stimulatory c type lectin receptor signaling pathway GO:0002223 2 0.037
cytokine secretion GO:0050663 72 0.037
negative regulation of apoptotic signaling pathway GO:2001234 104 0.037
mature dendritic cell differentiation GO:0097029 3 0.037
response to organonitrogen compound GO:0010243 246 0.036
negative regulation of leukocyte mediated immunity GO:0002704 29 0.036
cellular ketone metabolic process GO:0042180 84 0.036
inflammatory response to antigenic stimulus GO:0002437 30 0.036
positive regulation of lymphocyte differentiation GO:0045621 61 0.036
microglia development GO:0014005 2 0.035
sphingosine 1 phosphate signaling pathway GO:0003376 3 0.035
regulation of cell killing GO:0031341 40 0.035
regulation of interferon gamma production GO:0032649 57 0.034
positive regulation of innate immune response GO:0045089 80 0.034
production of molecular mediator of immune response GO:0002440 103 0.034
homeostasis of number of cells GO:0048872 210 0.034
regulation of acute inflammatory response to antigenic stimulus GO:0002864 10 0.034
forebrain development GO:0030900 302 0.034
positive regulation of tumor necrosis factor production GO:0032760 30 0.034
cellular response to lipid GO:0071396 145 0.034
regulation of stress activated mapk cascade GO:0032872 69 0.033
granulocyte migration GO:0097530 43 0.033
regulation of cellular response to stress GO:0080135 159 0.033
nitrogen compound transport GO:0071705 271 0.033
microglia differentiation GO:0014004 2 0.032
response to organic cyclic compound GO:0014070 198 0.032
organelle localization GO:0051640 179 0.032
regulation of ion transport GO:0043269 215 0.032
extrinsic apoptotic signaling pathway GO:0097191 126 0.032
regulation of mapk cascade GO:0043408 248 0.032
positive regulation of interferon alpha production GO:0032727 4 0.032
regulation of intracellular transport GO:0032386 159 0.032
negative regulation of intracellular signal transduction GO:1902532 167 0.032
response to lipopolysaccharide GO:0032496 128 0.031
ossification GO:0001503 216 0.031
positive regulation of phospholipase c activity GO:0010863 2 0.031
multicellular organismal homeostasis GO:0048871 164 0.031
interleukin 6 production GO:0032635 58 0.031
cerebral cortex development GO:0021987 86 0.031
regulation of extrinsic apoptotic signaling pathway GO:2001236 77 0.030
cellular ion homeostasis GO:0006873 165 0.030
cardiac muscle tissue growth involved in heart morphogenesis GO:0003245 1 0.030
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.030
myeloid leukocyte differentiation GO:0002573 119 0.030
transmembrane transport GO:0055085 412 0.030
positive regulation of leukocyte mediated cytotoxicity GO:0001912 31 0.030
positive regulation of defense response GO:0031349 124 0.030
nucleotide metabolic process GO:0009117 332 0.030
axonogenesis GO:0007409 274 0.030
positive regulation of glial cell differentiation GO:0045687 21 0.029
positive regulation of leukocyte mediated immunity GO:0002705 70 0.029
regulation of cellular amine metabolic process GO:0033238 20 0.029
alpha beta t cell proliferation GO:0046633 21 0.029
leukocyte mediated immunity GO:0002443 174 0.028
signal transduction in absence of ligand GO:0038034 55 0.028
regulation of innate immune response GO:0045088 91 0.028
cell chemotaxis GO:0060326 81 0.028
cognition GO:0050890 149 0.028
regulation of hypersensitivity GO:0002883 10 0.028
regulation of cell motility GO:2000145 236 0.028
neuronal action potential GO:0019228 54 0.028
detection of fungus GO:0016046 2 0.028
interferon gamma production GO:0032609 67 0.028
endomembrane system organization GO:0010256 147 0.028
exocytosis GO:0006887 121 0.027
negative regulation of lymphocyte activation GO:0051250 91 0.027
chemotaxis GO:0006935 247 0.027
calcium ion transport into cytosol GO:0060402 48 0.027
tolerance induction to self antigen GO:0002513 4 0.027
positive regulation of response to wounding GO:1903036 66 0.027
granulocyte activation GO:0036230 10 0.027
single organismal cell cell adhesion GO:0016337 131 0.027
cellular response to hormone stimulus GO:0032870 150 0.026
nucleobase containing small molecule metabolic process GO:0055086 352 0.026
antigen processing and presentation of peptide or polysaccharide antigen via mhc class ii GO:0002504 17 0.026
Mouse
sensory perception GO:0007600 245 0.026
positive regulation of kinase activity GO:0033674 155 0.026
regulation of multi organism process GO:0043900 111 0.026
glucose homeostasis GO:0042593 128 0.026
regulation of inflammatory response to antigenic stimulus GO:0002861 21 0.026
positive regulation of camp mediated signaling GO:0043950 3 0.025
cellular response to cytokine stimulus GO:0071345 189 0.025
positive regulation of interferon gamma production GO:0032729 39 0.025
positive regulation of t cell proliferation GO:0042102 52 0.025
regulation of cellular ketone metabolic process GO:0010565 66 0.025
morphogenesis of a branching epithelium GO:0061138 193 0.025
ras protein signal transduction GO:0007265 77 0.025
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 55 0.025
amine metabolic process GO:0009308 45 0.025
hypersensitivity GO:0002524 10 0.025
actin cytoskeleton organization GO:0030036 220 0.025
leukocyte mediated cytotoxicity GO:0001909 62 0.025
positive regulation of leukocyte proliferation GO:0070665 73 0.025
actin filament polymerization GO:0030041 44 0.025
action potential GO:0001508 78 0.024
regulation of t cell proliferation GO:0042129 92 0.024
positive regulation of transferase activity GO:0051347 167 0.024
antigen processing and presentation of exogenous peptide antigen via mhc class ii GO:0019886 14 0.024
Mouse
regulation of immunoglobulin mediated immune response GO:0002889 37 0.024
acute inflammatory response to antigenic stimulus GO:0002438 12 0.024
bone resorption GO:0045453 38 0.024
positive regulation of leukocyte differentiation GO:1902107 86 0.024
glycosyl compound catabolic process GO:1901658 206 0.024
plasma membrane organization GO:0007009 90 0.024
leukocyte degranulation GO:0043299 27 0.024
oxidation reduction process GO:0055114 342 0.024
positive regulation of acute inflammatory response to antigenic stimulus GO:0002866 7 0.024
cellular response to molecule of bacterial origin GO:0071219 83 0.024
telencephalon development GO:0021537 186 0.023
canonical wnt signaling pathway GO:0060070 130 0.023
glial cell differentiation GO:0010001 131 0.023
monocarboxylic acid metabolic process GO:0032787 191 0.023
ameboidal type cell migration GO:0001667 128 0.023
regulation of acute inflammatory response GO:0002673 27 0.023
b cell differentiation GO:0030183 78 0.023
regulation of cellular amino acid metabolic process GO:0006521 5 0.023
forebrain cell migration GO:0021885 58 0.023
lipid biosynthetic process GO:0008610 179 0.023
cytosolic calcium ion transport GO:0060401 48 0.023
activation of mapk activity GO:0000187 59 0.023
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.023
regulation of canonical wnt signaling pathway GO:0060828 82 0.023
regulation of cell cycle GO:0051726 281 0.023
regulation of gliogenesis GO:0014013 50 0.023
positive regulation of behavior GO:0048520 40 0.023
response to transforming growth factor beta GO:0071559 88 0.022
regulation of leukocyte degranulation GO:0043300 20 0.022
regulation of organelle organization GO:0033043 289 0.022
positive regulation of granulocyte chemotaxis GO:0071624 12 0.022
positive regulation of cell killing GO:0031343 33 0.022
innate immune response activating signal transduction GO:0002758 50 0.022
regulation of antigen receptor mediated signaling pathway GO:0050854 29 0.022
positive regulation of lymphocyte mediated immunity GO:0002708 62 0.022
regulation of protein secretion GO:0050708 82 0.022
cell type specific apoptotic process GO:0097285 268 0.022
cell growth GO:0016049 130 0.022
cytokine mediated signaling pathway GO:0019221 115 0.022
bone remodeling GO:0046849 53 0.022
regulation of calcium mediated signaling GO:0050848 19 0.022
neuron projection guidance GO:0097485 141 0.022
neural precursor cell proliferation GO:0061351 121 0.022
positive regulation of interleukin 2 production GO:0032743 19 0.021
regulation of interleukin 8 production GO:0032677 3 0.021
positive regulation of monocyte chemotaxis GO:0090026 2 0.021
morphogenesis of a branching structure GO:0001763 203 0.021
regulation of actin filament based process GO:0032970 99 0.021
immunoglobulin production GO:0002377 73 0.021
b cell receptor signaling pathway GO:0050853 20 0.021
peptidyl amino acid modification GO:0018193 336 0.021
innate immune response activating cell surface receptor signaling pathway GO:0002220 4 0.021
small gtpase mediated signal transduction GO:0007264 97 0.021
regulation of hydrolase activity GO:0051336 246 0.021
regulation of cell migration GO:0030334 219 0.021
positive regulation of cell death GO:0010942 224 0.021
germ cell development GO:0007281 185 0.021
regulation of kinase activity GO:0043549 249 0.021
protein secretion GO:0009306 111 0.020
negative regulation of regulated secretory pathway GO:1903306 7 0.020
regulation of cytokine secretion GO:0050707 61 0.020
cation transmembrane transport GO:0098655 266 0.020
regulation of ossification GO:0030278 112 0.020
negative regulation of lymphocyte proliferation GO:0050672 45 0.020
regulation of cell projection organization GO:0031344 206 0.020
regulation of metal ion transport GO:0010959 106 0.020
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.020
wnt signaling pathway GO:0016055 188 0.020
positive regulation of stress activated mapk cascade GO:0032874 48 0.020
organophosphate catabolic process GO:0046434 232 0.020
carbohydrate derivative catabolic process GO:1901136 231 0.020
nucleotide catabolic process GO:0009166 217 0.020
negative regulation of t cell activation GO:0050868 65 0.020
positive regulation of alpha beta t cell activation GO:0046635 39 0.020
lymphocyte migration GO:0072676 26 0.020
regulation of natural killer cell mediated cytotoxicity GO:0042269 19 0.020
regulation of leukocyte apoptotic process GO:2000106 56 0.019
defense response to bacterium GO:0042742 119 0.019
regulation of protein kinase activity GO:0045859 232 0.019
positive regulation of humoral immune response GO:0002922 11 0.019
positive regulation of cellular component biogenesis GO:0044089 94 0.019
carboxylic acid biosynthetic process GO:0046394 86 0.019
protein maturation GO:0051604 176 0.019
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger GO:0007187 55 0.019
kit signaling pathway GO:0038109 3 0.019
ribose phosphate metabolic process GO:0019693 291 0.019
interleukin 8 production GO:0032637 4 0.019
response to peptide hormone GO:0043434 127 0.019
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.019
regulation of myeloid cell apoptotic process GO:0033032 19 0.019
growth involved in heart morphogenesis GO:0003241 4 0.019
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 61 0.018
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 45 0.018
adenylate cyclase modulating g protein coupled receptor signaling pathway GO:0007188 54 0.018
negative regulation of molecular function GO:0044092 258 0.018
interleukin 1 production GO:0032612 31 0.018
regulation of natural killer cell mediated immunity GO:0002715 19 0.018
positive regulation of transcription from rna polymerase ii promoter involved in smooth muscle cell differentiation GO:2000721 2 0.018
cellular amine metabolic process GO:0044106 44 0.018
positive regulation of secretion GO:0051047 130 0.018
response to growth factor GO:0070848 198 0.018
b cell activation GO:0042113 161 0.018
endocytosis GO:0006897 168 0.018
natural killer cell activation GO:0030101 44 0.018
tissue remodeling GO:0048771 102 0.018
regulation of binding GO:0051098 111 0.018
positive regulation of oligodendrocyte differentiation GO:0048714 9 0.018
telencephalon cell migration GO:0022029 55 0.018
interleukin 1 beta production GO:0032611 30 0.018
macromolecule glycosylation GO:0043413 55 0.017
detection of yeast GO:0001879 2 0.017
nucleoside phosphate metabolic process GO:0006753 338 0.017
transforming growth factor beta receptor signaling pathway GO:0007179 71 0.017
myeloid leukocyte mediated immunity GO:0002444 42 0.017
i kappab kinase nf kappab signaling GO:0007249 85 0.017
organic acid biosynthetic process GO:0016053 86 0.017
positive regulation of chemotaxis GO:0050921 38 0.017
gliogenesis GO:0042063 141 0.017
stem cell development GO:0048864 219 0.017
purine ribonucleoside metabolic process GO:0046128 241 0.017
regulation of interleukin 1 beta production GO:0032651 25 0.017
regulation of myeloid cell differentiation GO:0045637 96 0.016
regulation of b cell activation GO:0050864 81 0.016
negative regulation of synapse assembly GO:0051964 3 0.016
reactive nitrogen species metabolic process GO:2001057 0 0.016
positive t cell selection GO:0043368 23 0.016
positive regulation of t helper 1 type immune response GO:0002827 12 0.016
positive regulation of nervous system development GO:0051962 221 0.016
regulation of peptide transport GO:0090087 91 0.016
epithelial cell proliferation GO:0050673 174 0.016
calcium ion transport GO:0006816 159 0.016
regulation of cellular component biogenesis GO:0044087 181 0.016
positive regulation of cell motility GO:2000147 116 0.016
regulation of response to wounding GO:1903034 189 0.016
purine containing compound metabolic process GO:0072521 311 0.016
positive regulation of antigen receptor mediated signaling pathway GO:0050857 9 0.016
intestinal epithelial structure maintenance GO:0060729 4 0.016
regulation of exocytosis GO:0017157 61 0.016
protein catabolic process GO:0030163 221 0.016
mast cell activation GO:0045576 27 0.016
mast cell proliferation GO:0070662 4 0.016
monosaccharide metabolic process GO:0005996 106 0.016
negative regulation of signal transduction in absence of ligand GO:1901099 16 0.016
protein folding GO:0006457 28 0.016
positive regulation of apoptotic process GO:0043065 217 0.016
positive regulation of dendritic cell antigen processing and presentation GO:0002606 7 0.016
nucleoside catabolic process GO:0009164 206 0.016
t cell receptor signaling pathway GO:0050852 46 0.016
muscle system process GO:0003012 141 0.016
cerebral cortex cell migration GO:0021795 44 0.016
tissue homeostasis GO:0001894 115 0.016
negative regulation of phagocytosis GO:0050765 4 0.016
cellular nitrogen compound catabolic process GO:0044270 280 0.016
meiotic cell cycle GO:0051321 122 0.016
regulation of anatomical structure size GO:0090066 178 0.015
nucleoside triphosphate metabolic process GO:0009141 230 0.015
activation of phospholipase c activity GO:0007202 2 0.015
adult behavior GO:0030534 135 0.015
protein processing GO:0016485 163 0.015
jnk cascade GO:0007254 72 0.015
reactive oxygen species metabolic process GO:0072593 84 0.015
response to extracellular stimulus GO:0009991 127 0.015
cellular extravasation GO:0045123 17 0.015
cytosolic calcium ion homeostasis GO:0051480 70 0.015
divalent metal ion transport GO:0070838 172 0.015
regulation of b cell proliferation GO:0030888 39 0.015
actin filament organization GO:0007015 113 0.015
aromatic compound catabolic process GO:0019439 286 0.015
natural killer cell mediated cytotoxicity GO:0042267 29 0.015
regulation of protein catabolic process GO:0042176 108 0.015
cellular response to growth factor stimulus GO:0071363 197 0.015
negative regulation of membrane potential GO:0045837 4 0.015
regulated secretory pathway GO:0045055 32 0.015
axon guidance GO:0007411 141 0.015
t cell mediated immunity GO:0002456 50 0.015
actin polymerization or depolymerization GO:0008154 54 0.015
regulation of cellular response to growth factor stimulus GO:0090287 82 0.015
cardiac muscle tissue development GO:0048738 130 0.015
positive regulation of endothelial cell proliferation GO:0001938 17 0.015
membrane lipid metabolic process GO:0006643 53 0.015
regulation of rho protein signal transduction GO:0035023 71 0.014
regulation of jnk cascade GO:0046328 62 0.014
positive regulation of inflammatory response to antigenic stimulus GO:0002863 11 0.014
neutrophil migration GO:1990266 37 0.014
response to host defenses GO:0052200 3 0.014
cellular response to lipopolysaccharide GO:0071222 77 0.014
single organism cell adhesion GO:0098602 156 0.014
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.014
positive regulation of protein kinase activity GO:0045860 144 0.014
regulation of glial cell differentiation GO:0045685 41 0.014
purine nucleoside catabolic process GO:0006152 205 0.014
protein localization to nucleus GO:0034504 121 0.014
lymphocyte apoptotic process GO:0070227 54 0.014
regulation of t cell differentiation GO:0045580 83 0.014
fc receptor mediated inhibitory signaling pathway GO:0002774 1 0.014
positive regulation of map kinase activity GO:0043406 84 0.014

H2-Ob disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
primary immunodeficiency disease DOID:612 0 0.066
immune system disease DOID:2914 0 0.066
disease of anatomical entity DOID:7 0 0.066
hematopoietic system disease DOID:74 0 0.032
blood protein disease DOID:620 0 0.024
agammaglobulinemia DOID:2583 0 0.022
common variable immunodeficiency DOID:12177 0 0.022
b cell deficiency DOID:2115 0 0.022
nervous system disease DOID:863 0 0.017