Mus musculus

62 known processes

Tlr1

toll-like receptor 1

Tlr1 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
defense response to other organism GO:0098542 197 0.551
Mouse
immune effector process GO:0002252 321 0.399
Mouse
cellular response to lipopolysaccharide GO:0071222 77 0.146
Mouse
immune response regulating signaling pathway GO:0002764 125 0.140
Mouse
activation of immune response GO:0002253 138 0.132
Mouse
regulation of cell activation GO:0050865 289 0.129
Mouse
regulation of innate immune response GO:0045088 91 0.121
Mouse
regulation of hydrolase activity GO:0051336 246 0.119
reactive oxygen species biosynthetic process GO:1903409 8 0.118
immune response regulating cell surface receptor signaling pathway GO:0002768 80 0.110
Mouse
immune response activating cell surface receptor signaling pathway GO:0002429 72 0.103
Mouse
cellular response to lipid GO:0071396 145 0.102
Mouse
regulation of defense response GO:0031347 233 0.096
Mouse
immune response activating signal transduction GO:0002757 116 0.093
Mouse
positive regulation of innate immune response GO:0045089 80 0.090
Mouse
membrane organization GO:0061024 245 0.084
cellular response to biotic stimulus GO:0071216 92 0.080
Human Mouse
positive regulation of cytokine production GO:0001819 174 0.079
purine containing compound metabolic process GO:0072521 311 0.077
leukocyte activation involved in immune response GO:0002366 126 0.076
Mouse
regulation of secretion GO:0051046 274 0.073
Mouse
lymphocyte mediated immunity GO:0002449 139 0.071
negative regulation of cellular protein metabolic process GO:0032269 247 0.070
purine nucleoside metabolic process GO:0042278 241 0.068
nucleobase containing small molecule metabolic process GO:0055086 352 0.068
response to molecule of bacterial origin GO:0002237 143 0.067
Human Mouse
activation of innate immune response GO:0002218 56 0.065
Mouse
response to molecule of fungal origin GO:0002238 4 0.064
Mouse
lymphocyte proliferation GO:0046651 164 0.063
Mouse
cellular amino acid metabolic process GO:0006520 103 0.062
regulation of cellular ketone metabolic process GO:0010565 66 0.060
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.060
regulation of secretion by cell GO:1903530 249 0.058
Mouse
t cell activation GO:0042110 289 0.058
cation transport GO:0006812 399 0.057
mapk cascade GO:0000165 281 0.055
Mouse
cellular amine metabolic process GO:0044106 44 0.055
multicellular organismal homeostasis GO:0048871 164 0.055
Mouse
leukocyte mediated immunity GO:0002443 174 0.054
cellular nitrogen compound catabolic process GO:0044270 280 0.054
purine ribonucleoside catabolic process GO:0046130 205 0.053
positive regulation of interferon alpha production GO:0032727 4 0.053
Mouse
ribonucleoside metabolic process GO:0009119 245 0.052
regulation of protein transport GO:0051223 163 0.052
Mouse
glycosyl compound catabolic process GO:1901658 206 0.052
aromatic compound catabolic process GO:0019439 286 0.052
regulation of cellular catabolic process GO:0031329 242 0.051
cellular chemical homeostasis GO:0055082 215 0.051
guanosine containing compound catabolic process GO:1901069 144 0.050
cellular homeostasis GO:0019725 240 0.050
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.050
b cell activation GO:0042113 161 0.049
Mouse
cellular divalent inorganic cation homeostasis GO:0072503 127 0.049
positive regulation of secretion by cell GO:1903532 114 0.049
Mouse
pattern recognition receptor signaling pathway GO:0002221 47 0.049
Mouse
cellular response to cytokine stimulus GO:0071345 189 0.048
regulation of leukocyte proliferation GO:0070663 121 0.048
Mouse
regulation of mapk cascade GO:0043408 248 0.048
Mouse
cell activation involved in immune response GO:0002263 126 0.047
Mouse
negative regulation of cellular amine metabolic process GO:0033239 1 0.047
adaptive immune response GO:0002250 155 0.047
glycosyl compound metabolic process GO:1901657 246 0.046
defense response to virus GO:0051607 68 0.046
cell surface pattern recognition receptor signaling pathway GO:0002752 2 0.046
Mouse
leukocyte differentiation GO:0002521 342 0.046
regulation of cell migration GO:0030334 219 0.046
Mouse
nucleoside phosphate metabolic process GO:0006753 338 0.046
carbohydrate derivative catabolic process GO:1901136 231 0.046
cellular response to peptidoglycan GO:0071224 4 0.046
Mouse
sequestering of calcium ion GO:0051208 18 0.045
ribonucleoside catabolic process GO:0042454 206 0.045
cellular metal ion homeostasis GO:0006875 151 0.045
cytokine production GO:0001816 319 0.045
lymphocyte activation involved in immune response GO:0002285 93 0.045
Mouse
nucleoside metabolic process GO:0009116 246 0.045
regulation of establishment of protein localization GO:0070201 181 0.044
Mouse
heterocycle catabolic process GO:0046700 280 0.044
organic cyclic compound catabolic process GO:1901361 295 0.044
purine ribonucleotide metabolic process GO:0009150 290 0.043
hematopoietic progenitor cell differentiation GO:0002244 143 0.043
negative regulation of phosphorus metabolic process GO:0010563 184 0.043
Mouse
organonitrogen compound catabolic process GO:1901565 264 0.043
defense response to bacterium GO:0042742 119 0.042
Mouse
negative regulation of molecular function GO:0044092 258 0.042
ribonucleotide catabolic process GO:0009261 208 0.042
negative regulation of protein metabolic process GO:0051248 282 0.041
positive regulation of programmed cell death GO:0043068 218 0.041
amine metabolic process GO:0009308 45 0.041
rho protein signal transduction GO:0007266 32 0.040
b cell proliferation GO:0042100 53 0.040
Mouse
cellular response to molecule of bacterial origin GO:0071219 83 0.040
Human Mouse
leukocyte proliferation GO:0070661 172 0.039
Mouse
intestinal epithelial structure maintenance GO:0060729 4 0.039
Mouse
nucleotide metabolic process GO:0009117 332 0.038
nucleoside triphosphate metabolic process GO:0009141 230 0.037
nucleoside catabolic process GO:0009164 206 0.037
regulation of interferon beta biosynthetic process GO:0045357 4 0.037
Mouse
response to lipopolysaccharide GO:0032496 128 0.037
Mouse
negative regulation of immune system process GO:0002683 209 0.037
purine nucleotide metabolic process GO:0006163 302 0.037
purine ribonucleoside metabolic process GO:0046128 241 0.036
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.036
nucleotide catabolic process GO:0009166 217 0.036
purine ribonucleotide catabolic process GO:0009154 208 0.036
regulation of protein secretion GO:0050708 82 0.036
Mouse
negative regulation of phosphorylation GO:0042326 166 0.036
Mouse
regulation of body fluid levels GO:0050878 162 0.036
Mouse
nucleoside phosphate catabolic process GO:1901292 222 0.036
cytoplasmic transport GO:0016482 234 0.035
positive regulation of secretion GO:0051047 130 0.035
Mouse
sequestering of metal ion GO:0051238 19 0.035
response to organic cyclic compound GO:0014070 198 0.035
detection of bacterium GO:0016045 7 0.035
Human
regulation of inflammatory response GO:0050727 147 0.035
Mouse
cellular ion homeostasis GO:0006873 165 0.035
regulation of cellular component biogenesis GO:0044087 181 0.034
regulation of protein localization GO:0032880 231 0.034
Mouse
b cell activation involved in immune response GO:0002312 50 0.034
Mouse
gtp catabolic process GO:0006184 143 0.034
regulation of lymphocyte activation GO:0051249 240 0.033
Mouse
regulation of cytokine production GO:0001817 266 0.033
protein maturation GO:0051604 176 0.033
purine nucleoside catabolic process GO:0006152 205 0.033
regulation of organelle organization GO:0033043 289 0.032
cellular ketone metabolic process GO:0042180 84 0.032
innate immune response GO:0045087 157 0.032
Mouse
reactive nitrogen species metabolic process GO:2001057 0 0.032
protein processing GO:0016485 163 0.032
regulation of ion transport GO:0043269 215 0.032
ribonucleoside triphosphate metabolic process GO:0009199 220 0.032
regulation of lymphocyte proliferation GO:0050670 117 0.032
Mouse
detection of stimulus GO:0051606 84 0.032
Human
positive regulation of defense response GO:0031349 124 0.032
Mouse
tumor necrosis factor superfamily cytokine production GO:0071706 51 0.031
regulation of leukocyte mediated immunity GO:0002703 104 0.031
positive regulation of immune effector process GO:0002699 107 0.031
Mouse
positive regulation of gtp catabolic process GO:0033126 85 0.031
myeloid cell differentiation GO:0030099 233 0.031
cellular calcium ion homeostasis GO:0006874 119 0.030
cytokine secretion GO:0050663 72 0.030
Mouse
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.030
negative regulation of hydrolase activity GO:0051346 71 0.030
ribonucleotide metabolic process GO:0009259 291 0.030
erk1 and erk2 cascade GO:0070371 77 0.030
Mouse
g protein coupled receptor signaling pathway GO:0007186 243 0.029
regulation of proteolysis GO:0030162 164 0.029
positive regulation of reactive oxygen species metabolic process GO:2000379 11 0.029
reactive oxygen species metabolic process GO:0072593 84 0.029
organophosphate catabolic process GO:0046434 232 0.028
anatomical structure homeostasis GO:0060249 145 0.028
Mouse
ribose phosphate metabolic process GO:0019693 291 0.028
regulation of cellular amino acid metabolic process GO:0006521 5 0.028
regulation of nucleotide metabolic process GO:0006140 169 0.028
divalent inorganic cation transport GO:0072511 178 0.028
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.027
t cell proliferation GO:0042098 120 0.027
purine containing compound catabolic process GO:0072523 213 0.027
response to organonitrogen compound GO:0010243 246 0.027
Mouse
metal ion homeostasis GO:0055065 189 0.027
calcium ion transport GO:0006816 159 0.027
regulation of b cell activation GO:0050864 81 0.027
Mouse
regulation of cellular amine metabolic process GO:0033238 20 0.027
purine nucleoside triphosphate catabolic process GO:0009146 203 0.026
gtp metabolic process GO:0046039 144 0.026
cell type specific apoptotic process GO:0097285 268 0.026
ribonucleoside triphosphate catabolic process GO:0009203 199 0.026
regulation of protein complex assembly GO:0043254 83 0.026
positive regulation of hydrolase activity GO:0051345 148 0.026
positive regulation of cellular amine metabolic process GO:0033240 5 0.026
maintenance of location GO:0051235 89 0.025
positive regulation of cell motility GO:2000147 116 0.025
Mouse
myeloid leukocyte differentiation GO:0002573 119 0.025
cytosolic calcium ion homeostasis GO:0051480 70 0.025
calcium ion homeostasis GO:0055074 127 0.025
regulation of protein serine threonine kinase activity GO:0071900 157 0.025
Mouse
detection of biotic stimulus GO:0009595 10 0.025
Human
regulation of ion homeostasis GO:2000021 64 0.024
homeostasis of number of cells GO:0048872 210 0.024
sensory perception GO:0007600 245 0.024
purine nucleoside triphosphate metabolic process GO:0009144 226 0.024
inflammatory response GO:0006954 244 0.024
Mouse
negative regulation of protein modification process GO:0031400 163 0.024
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.024
negative regulation of phosphate metabolic process GO:0045936 184 0.024
Mouse
ras protein signal transduction GO:0007265 77 0.024
cell adhesion GO:0007155 329 0.024
guanosine containing compound metabolic process GO:1901068 144 0.024
divalent metal ion transport GO:0070838 172 0.023
cation homeostasis GO:0055080 212 0.023
transmembrane transport GO:0055085 412 0.023
cation transmembrane transport GO:0098655 266 0.023
ossification GO:0001503 216 0.022
regulation of cell adhesion GO:0030155 154 0.022
positive regulation of gtpase activity GO:0043547 85 0.022
organonitrogen compound biosynthetic process GO:1901566 192 0.022
carbohydrate derivative biosynthetic process GO:1901137 183 0.022
regulation of cellular response to stress GO:0080135 159 0.022
Mouse
regulation of peptidase activity GO:0052547 96 0.022
protein modification by small protein conjugation or removal GO:0070647 207 0.022
muscle cell differentiation GO:0042692 261 0.022
posttranscriptional regulation of gene expression GO:0010608 155 0.022
membrane fusion GO:0061025 38 0.022
pyroptosis GO:0070269 8 0.021
divalent inorganic cation homeostasis GO:0072507 138 0.021
inorganic ion transmembrane transport GO:0098660 234 0.021
regulation of multi organism process GO:0043900 111 0.021
Mouse
regulation of t cell activation GO:0050863 170 0.021
positive regulation of protein secretion GO:0050714 52 0.021
Mouse
regulation of membrane potential GO:0042391 192 0.021
regulation of nucleotide catabolic process GO:0030811 122 0.020
regulation of purine nucleotide metabolic process GO:1900542 169 0.020
leukocyte migration GO:0050900 124 0.020
Mouse
regulation of response to biotic stimulus GO:0002831 38 0.020
Mouse
regulation of anatomical structure size GO:0090066 178 0.020
negative regulation of protein processing GO:0010955 79 0.020
apoptotic signaling pathway GO:0097190 306 0.020
positive regulation of erk1 and erk2 cascade GO:0070374 47 0.020
Mouse
regulation of nucleoside metabolic process GO:0009118 130 0.020
protein ubiquitination GO:0016567 171 0.020
cellular response to growth factor stimulus GO:0071363 197 0.020
positive regulation of protein transport GO:0051222 93 0.020
Mouse
purinergic nucleotide receptor signaling pathway GO:0035590 3 0.020
positive regulation of cytokine secretion GO:0050715 41 0.020
Mouse
nucleoside triphosphate catabolic process GO:0009143 205 0.020
protein modification by small protein conjugation GO:0032446 187 0.019
ion transmembrane transport GO:0034220 361 0.019
i kappab kinase nf kappab signaling GO:0007249 85 0.019
Mouse
regulation of erk1 and erk2 cascade GO:0070372 71 0.019
Mouse
negative regulation of cell proliferation GO:0008285 296 0.019
stem cell differentiation GO:0048863 268 0.019
defense response to gram positive bacterium GO:0050830 50 0.019
Mouse
endocytosis GO:0006897 168 0.019
purine nucleotide catabolic process GO:0006195 211 0.019
positive regulation of mapk cascade GO:0043410 170 0.019
Mouse
protein catabolic process GO:0030163 221 0.019
positive regulation of nucleotide catabolic process GO:0030813 88 0.019
neuron apoptotic process GO:0051402 142 0.019
actin cytoskeleton organization GO:0030036 220 0.019
transmission of nerve impulse GO:0019226 76 0.019
negative regulation of cellular component organization GO:0051129 194 0.019
regulation of reactive oxygen species metabolic process GO:2000377 40 0.018
spermatogenesis GO:0007283 284 0.018
oxidation reduction process GO:0055114 342 0.018
intracellular receptor signaling pathway GO:0030522 74 0.018
Mouse
inorganic cation transmembrane transport GO:0098662 207 0.018
positive regulation of cytosolic calcium ion concentration GO:0007204 65 0.018
regulation of lymphocyte mediated immunity GO:0002706 84 0.018
interferon gamma production GO:0032609 67 0.018
Mouse
regulation of actin filament based process GO:0032970 99 0.018
gland development GO:0048732 330 0.018
regulation of endopeptidase activity GO:0052548 89 0.018
regulation of interleukin 18 production GO:0032661 3 0.018
Mouse
regulation of ossification GO:0030278 112 0.018
positive regulation of protein modification process GO:0031401 299 0.018
Mouse
macromolecule catabolic process GO:0009057 281 0.018
dna metabolic process GO:0006259 303 0.018
positive regulation of cell development GO:0010720 237 0.018
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.018
tissue homeostasis GO:0001894 115 0.018
Mouse
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.018
regulation of neuron differentiation GO:0045664 281 0.018
regulation of neuron death GO:1901214 134 0.018
response to radiation GO:0009314 165 0.017
response to growth factor GO:0070848 198 0.017
regulation of vesicle mediated transport GO:0060627 139 0.017
release of sequestered calcium ion into cytosol GO:0051209 42 0.017
epithelial tube morphogenesis GO:0060562 303 0.017
protein secretion GO:0009306 111 0.017
Mouse
positive regulation of cell activation GO:0050867 158 0.017
Mouse
negative regulation of cytokine production GO:0001818 84 0.017
Mouse
cell killing GO:0001906 67 0.017
action potential GO:0001508 78 0.017
t cell differentiation GO:0030217 174 0.017
regulation of protein processing GO:0070613 96 0.017
regulation of system process GO:0044057 200 0.017
negative regulation of protein maturation GO:1903318 79 0.017
vesicle organization GO:0016050 60 0.017
digestive system development GO:0055123 200 0.017
small gtpase mediated signal transduction GO:0007264 97 0.017
endomembrane system organization GO:0010256 147 0.017
regulation of cell projection organization GO:0031344 206 0.017
antimicrobial peptide biosynthetic process GO:0002777 2 0.017
regulation of antimicrobial peptide biosynthetic process GO:0002805 1 0.017
digestion GO:0007586 40 0.016
Mouse
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.016
peptide transport GO:0015833 133 0.016
negative regulation of multi organism process GO:0043901 68 0.016
Mouse
organic hydroxy compound metabolic process GO:1901615 203 0.016
multicellular organismal signaling GO:0035637 91 0.016
morphogenesis of embryonic epithelium GO:0016331 159 0.016
innate immune response activating cell surface receptor signaling pathway GO:0002220 4 0.016
Mouse
toll like receptor signaling pathway GO:0002224 38 0.016
Mouse
positive regulation of purine nucleotide catabolic process GO:0033123 88 0.016
stress activated protein kinase signaling cascade GO:0031098 81 0.016
Mouse
regulation of protein maturation GO:1903317 96 0.016
regulation of cell motility GO:2000145 236 0.016
Mouse
regulation of intracellular transport GO:0032386 159 0.016
positive regulation of nucleotide metabolic process GO:0045981 114 0.016
regulation of purine nucleotide catabolic process GO:0033121 122 0.016
intrinsic apoptotic signaling pathway GO:0097193 132 0.016
regulation of b cell proliferation GO:0030888 39 0.016
Mouse
neuronal action potential GO:0019228 54 0.016
regulation of cytokine biosynthetic process GO:0042035 59 0.016
regulation of jnk cascade GO:0046328 62 0.016
Mouse
neuron death GO:0070997 154 0.016
regulation of metal ion transport GO:0010959 106 0.016
positive regulation of cellular catabolic process GO:0031331 148 0.016
positive regulation of antimicrobial peptide production GO:0002225 1 0.016
detection of other organism GO:0098543 8 0.015
Human
nitrogen compound transport GO:0071705 271 0.015
antigen receptor mediated signaling pathway GO:0050851 64 0.015
transepithelial chloride transport GO:0030321 4 0.015
glycoprotein metabolic process GO:0009100 116 0.015
cellular response to abiotic stimulus GO:0071214 56 0.015
toll like receptor 7 signaling pathway GO:0034154 4 0.015
regulation of interferon beta production GO:0032648 13 0.015
Mouse
organophosphate biosynthetic process GO:0090407 122 0.015
regulation of ras protein signal transduction GO:0046578 114 0.015
skin development GO:0043588 220 0.015
positive regulation of cell death GO:0010942 224 0.015
carbohydrate homeostasis GO:0033500 128 0.015
response to drug GO:0042493 75 0.015
Mouse
regulation of cysteine type endopeptidase activity GO:2000116 65 0.015
regulation of transferase activity GO:0051338 263 0.015
Mouse
leukocyte homeostasis GO:0001776 79 0.015
cellular lipid metabolic process GO:0044255 323 0.015
positive regulation of cellular component biogenesis GO:0044089 94 0.015
alpha beta t cell activation GO:0046631 91 0.015
axonogenesis GO:0007409 274 0.015
peptidyl amino acid modification GO:0018193 336 0.015
regulation of leukocyte differentiation GO:1902105 159 0.015
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.015
regulation of cytoskeleton organization GO:0051493 122 0.015
negative regulation of cell activation GO:0050866 111 0.015
cellular response to interferon beta GO:0035458 21 0.014
regulation of cell cycle process GO:0010564 160 0.014
skeletal system development GO:0001501 356 0.014
negative regulation of ripoptosome assembly involved in necroptotic process GO:1902443 3 0.014
interferon beta biosynthetic process GO:0045350 4 0.014
Mouse
regulation of cell cycle GO:0051726 281 0.014
protein localization to membrane GO:0072657 108 0.014
regulation of interleukin 1 alpha production GO:0032650 4 0.014
glucose homeostasis GO:0042593 128 0.014
regulation of osteoblast differentiation GO:0045667 67 0.014
calcium ion transport into cytosol GO:0060402 48 0.014
negative regulation of proteolysis GO:0045861 74 0.014
modification by symbiont of host morphology or physiology GO:0044003 4 0.014
Mouse
tube formation GO:0035148 140 0.014
cellular response to dna damage stimulus GO:0006974 207 0.014
positive regulation by symbiont of defense related host nitric oxide production GO:0052347 1 0.014
Mouse
cellular response to hormone stimulus GO:0032870 150 0.014
positive regulation by symbiont of host defense response GO:0052509 1 0.014
Mouse
microtubule based process GO:0007017 236 0.014
actin filament polymerization GO:0030041 44 0.014
positive regulation of apoptotic process GO:0043065 217 0.014
regulation of tumor necrosis factor production GO:0032680 49 0.014
dephosphorylation GO:0016311 129 0.014
chemotaxis GO:0006935 247 0.014
cellular response to organonitrogen compound GO:0071417 145 0.014
Mouse
regulation of map kinase activity GO:0043405 120 0.014
Mouse
innate immune response activating signal transduction GO:0002758 50 0.014
Mouse
response to bacterial lipopeptide GO:0070339 3 0.014
Human Mouse
nitric oxide biosynthetic process GO:0006809 25 0.014
Mouse
regulation of actin cytoskeleton organization GO:0032956 84 0.014
compound eye development GO:0048749 1 0.014
positive regulation of leukocyte proliferation GO:0070665 73 0.014
Mouse
nucleocytoplasmic transport GO:0006913 139 0.014
thrombin receptor signaling pathway GO:0070493 2 0.014
regulation of homeostatic process GO:0032844 182 0.013
regulation of t cell proliferation GO:0042129 92 0.013
regulation of cytoplasmic transport GO:1903649 112 0.013
actin polymerization or depolymerization GO:0008154 54 0.013
cytokine metabolic process GO:0042107 71 0.013
negative regulation of intracellular signal transduction GO:1902532 167 0.013
Mouse
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.013
positive regulation of kinase activity GO:0033674 155 0.013
Mouse
digestive tract development GO:0048565 190 0.013
negative regulation of t cell activation GO:0050868 65 0.013
regulation of protein catabolic process GO:0042176 108 0.013
regulation of cytokine secretion GO:0050707 61 0.013
Mouse
alpha beta t cell differentiation GO:0046632 69 0.013
antimicrobial peptide production GO:0002775 2 0.013
anion transport GO:0006820 177 0.013
regulation of intracellular protein transport GO:0033157 82 0.013
negative regulation of protein phosphorylation GO:0001933 126 0.013
regulation of natural killer cell activation GO:0032814 22 0.013
organic hydroxy compound transport GO:0015850 93 0.013
forebrain development GO:0030900 302 0.013
positive regulation of lymphocyte activation GO:0051251 140 0.013
Mouse
negative regulation of chromatin silencing GO:0031936 1 0.013
blood circulation GO:0008015 195 0.013
jnk cascade GO:0007254 72 0.013
Mouse
interleukin 18 production GO:0032621 4 0.013
Mouse
negative regulation of growth GO:0045926 99 0.013
Mouse
regulation of interleukin 1 beta production GO:0032651 25 0.013
carbohydrate metabolic process GO:0005975 230 0.012
negative regulation of mapk cascade GO:0043409 65 0.012
Mouse
ear development GO:0043583 200 0.012
negative regulation of b cell receptor signaling pathway GO:0050859 4 0.012
inorganic anion transport GO:0015698 43 0.012
vesicle fusion GO:0006906 16 0.012
neural tube formation GO:0001841 108 0.012
positive regulation of interferon gamma production GO:0032729 39 0.012
Mouse
positive regulation of stress activated mapk cascade GO:0032874 48 0.012
Mouse
response to host defenses GO:0052200 3 0.012
Mouse
male gamete generation GO:0048232 285 0.012
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 62 0.012
regulation of gtp catabolic process GO:0033124 113 0.012
positive regulation of cell migration GO:0030335 109 0.012
Mouse
intracellular protein transport GO:0006886 204 0.012
positive regulation of antimicrobial peptide biosynthetic process GO:0002807 1 0.012
glycoprotein biosynthetic process GO:0009101 89 0.012
negative regulation of lymphocyte activation GO:0051250 91 0.012
modulation by symbiont of host immune response GO:0052553 1 0.012
Mouse
production of molecular mediator of immune response GO:0002440 103 0.012
Mouse
type i interferon production GO:0032606 29 0.012
Mouse
interferon beta production GO:0032608 16 0.012
Mouse
mitotic cell cycle GO:0000278 195 0.012
negative regulation of gene silencing GO:0060969 2 0.012
regulation of type i interferon production GO:0032479 22 0.012
Mouse
regulation of hormone levels GO:0010817 211 0.012
regulation of antimicrobial peptide production GO:0002784 1 0.012
interspecies interaction between organisms GO:0044419 83 0.012
Mouse
leukocyte mediated cytotoxicity GO:0001909 62 0.012
negative regulation of peptidase activity GO:0010466 46 0.012
organelle assembly GO:0070925 177 0.012
epithelial structure maintenance GO:0010669 9 0.012
Mouse
positive regulation of protein kinase activity GO:0045860 144 0.011
Mouse
regulation of tumor necrosis factor superfamily cytokine production GO:1903555 50 0.011
cd4 positive alpha beta t cell activation GO:0035710 45 0.011
dna modification GO:0006304 50 0.011
blood coagulation GO:0007596 76 0.011
Mouse
retrograde transport endosome to golgi GO:0042147 2 0.011
renal system development GO:0072001 225 0.011
kidney development GO:0001822 213 0.011
monocarboxylic acid metabolic process GO:0032787 191 0.011
muscle system process GO:0003012 141 0.011
positive regulation of cytokine biosynthetic process GO:0042108 40 0.011
dna recombination GO:0006310 92 0.011
response to acid chemical GO:0001101 111 0.011
positive regulation of production of molecular mediator of immune response GO:0002702 45 0.011
Mouse
protein localization to organelle GO:0033365 185 0.011
regulation of cell killing GO:0031341 40 0.011
induction by organism of immune response of other organism involved in symbiotic interaction GO:0052558 1 0.011
Mouse
regulation of blood circulation GO:1903522 93 0.011
regulation of antimicrobial humoral response GO:0002759 3 0.011
negative regulation of myeloid cell differentiation GO:0045638 38 0.011
positive regulation of nucleoside metabolic process GO:0045979 91 0.011
morphogenesis of a branching structure GO:0001763 203 0.011
immunoglobulin production GO:0002377 73 0.011
regulation of stress activated mapk cascade GO:0032872 69 0.011
Mouse
peptide metabolic process GO:0006518 46 0.011
negative regulation of organelle organization GO:0010639 90 0.011
positive regulation of t cell extravasation GO:2000409 2 0.011
nucleotide biosynthetic process GO:0009165 78 0.011
regulation of renin secretion into blood stream GO:1900133 4 0.011
developmental maturation GO:0021700 193 0.011
stem cell development GO:0048864 219 0.011
regulation of response to wounding GO:1903034 189 0.011
Mouse
regulation of interleukin 10 production GO:0032653 21 0.011
Mouse
positive regulation of nervous system development GO:0051962 221 0.011
regulation of apoptotic signaling pathway GO:2001233 197 0.011
cognition GO:0050890 149 0.011
interleukin 8 production GO:0032637 4 0.011
positive regulation of coagulation GO:0050820 13 0.011
Mouse
respiratory tube development GO:0030323 167 0.010
cellular protein complex assembly GO:0043623 116 0.010
epithelial tube formation GO:0072175 130 0.010
circulatory system process GO:0003013 197 0.010
positive regulation of leukocyte mediated immunity GO:0002705 70 0.010
peptide hormone secretion GO:0030072 109 0.010
lipid biosynthetic process GO:0008610 179 0.010
cytokine biosynthetic process GO:0042089 68 0.010
positive regulation of endocytosis GO:0045807 42 0.010
cytosolic calcium ion transport GO:0060401 48 0.010
organelle localization GO:0051640 179 0.010
regulation of extrinsic apoptotic signaling pathway GO:2001236 77 0.010
placenta development GO:0001890 140 0.010
cellular macromolecule catabolic process GO:0044265 206 0.010
positive regulation of organelle organization GO:0010638 128 0.010
morphogenesis of a branching epithelium GO:0061138 193 0.010
alcohol metabolic process GO:0006066 116 0.010
plasma membrane organization GO:0007009 90 0.010
detection of external biotic stimulus GO:0098581 9 0.010
Human
spermatid differentiation GO:0048515 115 0.010
lateral inhibition GO:0046331 1 0.010
chloride transport GO:0006821 32 0.010
chromatin modification GO:0016568 187 0.010
cell fate commitment GO:0045165 210 0.010
second messenger mediated signaling GO:0019932 73 0.010
organelle fusion GO:0048284 28 0.010

Tlr1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.018
disease of anatomical entity DOID:7 0 0.015
musculoskeletal system disease DOID:17 0 0.015
connective tissue disease DOID:65 0 0.015
nervous system disease DOID:863 0 0.014