Mus musculus

0 known processes

Tlr5

toll-like receptor 5

Tlr5 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
g protein coupled receptor signaling pathway GO:0007186 243 0.557
defense response to other organism GO:0098542 197 0.311
Mouse
response to molecule of bacterial origin GO:0002237 143 0.265
Mouse
toll like receptor signaling pathway GO:0002224 38 0.264
Human Mouse
regulation of secretion by cell GO:1903530 249 0.214
Mouse
immune response regulating signaling pathway GO:0002764 125 0.212
Human Mouse
regulation of defense response GO:0031347 233 0.206
Human Mouse
adenylate cyclase modulating g protein coupled receptor signaling pathway GO:0007188 54 0.195
cellular metal ion homeostasis GO:0006875 151 0.194
regulation of cellular amine metabolic process GO:0033238 20 0.194
regulation of inflammatory response GO:0050727 147 0.190
Mouse
innate immune response GO:0045087 157 0.182
Mouse
calcium ion homeostasis GO:0055074 127 0.170
ion transmembrane transport GO:0034220 361 0.169
positive regulation of innate immune response GO:0045089 80 0.167
Human Mouse
organic hydroxy compound transport GO:0015850 93 0.165
metal ion homeostasis GO:0055065 189 0.163
activation of immune response GO:0002253 138 0.153
Human Mouse
positive regulation of secretion GO:0051047 130 0.138
Mouse
nucleoside phosphate metabolic process GO:0006753 338 0.134
i kappab kinase nf kappab signaling GO:0007249 85 0.129
Mouse
protein secretion GO:0009306 111 0.129
Mouse
positive regulation of defense response GO:0031349 124 0.127
Human Mouse
regulation of lymphocyte activation GO:0051249 240 0.126
Mouse
response to organonitrogen compound GO:0010243 246 0.124
Mouse
regulation of protein localization GO:0032880 231 0.123
Mouse
myeloid cell differentiation GO:0030099 233 0.123
positive regulation of cellular amine metabolic process GO:0033240 5 0.121
ribose phosphate metabolic process GO:0019693 291 0.121
positive regulation of cytokine production GO:0001819 174 0.119
Human Mouse
mapk cascade GO:0000165 281 0.119
Mouse
positive regulation of mapk cascade GO:0043410 170 0.117
Mouse
regulation of body fluid levels GO:0050878 162 0.112
Mouse
immune effector process GO:0002252 321 0.110
Mouse
cellular chemical homeostasis GO:0055082 215 0.110
cellular calcium ion homeostasis GO:0006874 119 0.110
positive regulation of secretion by cell GO:1903532 114 0.110
Mouse
regulation of leukocyte proliferation GO:0070663 121 0.109
Mouse
cytokine secretion GO:0050663 72 0.108
Mouse
cellular ion homeostasis GO:0006873 165 0.107
regulation of cell activation GO:0050865 289 0.104
Mouse
cation transport GO:0006812 399 0.103
cellular amine metabolic process GO:0044106 44 0.103
cation homeostasis GO:0055080 212 0.101
positive regulation of tumor necrosis factor production GO:0032760 30 0.099
Mouse
defense response to bacterium GO:0042742 119 0.099
Mouse
negative regulation of intracellular signal transduction GO:1902532 167 0.098
Mouse
regulation of lymphocyte proliferation GO:0050670 117 0.097
Mouse
cytokine production GO:0001816 319 0.097
Human Mouse
cytokine biosynthetic process GO:0042089 68 0.097
Mouse
regulation of establishment of protein localization GO:0070201 181 0.096
Mouse
cytokine production involved in immune response GO:0002367 34 0.095
Mouse
regulation of secretion GO:0051046 274 0.093
Mouse
reactive nitrogen species metabolic process GO:2001057 0 0.093
interleukin 12 production GO:0032615 32 0.093
Mouse
transmembrane transport GO:0055085 412 0.093
t cell activation GO:0042110 289 0.091
cellular response to lipid GO:0071396 145 0.090
Mouse
regulation of interleukin 1 production GO:0032652 26 0.090
Mouse
hemostasis GO:0007599 78 0.089
Mouse
regulation of cell migration GO:0030334 219 0.086
Mouse
purine ribonucleotide metabolic process GO:0009150 290 0.085
regulation of interferon gamma production GO:0032649 57 0.085
Mouse
lipid localization GO:0010876 126 0.083
leukocyte differentiation GO:0002521 342 0.081
regulation of cytokine secretion GO:0050707 61 0.080
Mouse
cellular ketone metabolic process GO:0042180 84 0.078
regulation of cytokine production GO:0001817 266 0.078
Human Mouse
pattern recognition receptor signaling pathway GO:0002221 47 0.078
Human Mouse
germ cell development GO:0007281 185 0.076
cellular response to lipopolysaccharide GO:0071222 77 0.075
Mouse
maintenance of location GO:0051235 89 0.074
amine metabolic process GO:0009308 45 0.073
positive regulation of cytokine biosynthetic process GO:0042108 40 0.073
Mouse
regulation of membrane potential GO:0042391 192 0.071
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.071
regulation of interleukin 12 production GO:0032655 30 0.070
Mouse
synaptic transmission GO:0007268 329 0.068
cell type specific apoptotic process GO:0097285 268 0.067
regulation of ion transport GO:0043269 215 0.067
hematopoietic progenitor cell differentiation GO:0002244 143 0.067
regulation of cellular ketone metabolic process GO:0010565 66 0.066
regulation of protein serine threonine kinase activity GO:0071900 157 0.066
Mouse
positive regulation of cell activation GO:0050867 158 0.065
Mouse
positive regulation of interferon alpha production GO:0032727 4 0.065
Mouse
regulation of cellular component biogenesis GO:0044087 181 0.064
divalent inorganic cation transport GO:0072511 178 0.064
regulation of protein transport GO:0051223 163 0.064
Mouse
regulation of metal ion transport GO:0010959 106 0.063
immune response activating signal transduction GO:0002757 116 0.063
Human Mouse
lymphocyte proliferation GO:0046651 164 0.063
Mouse
intracellular receptor signaling pathway GO:0030522 74 0.063
Mouse
divalent inorganic cation homeostasis GO:0072507 138 0.062
purine containing compound biosynthetic process GO:0072522 70 0.062
negative regulation of defense response GO:0031348 77 0.061
blood circulation GO:0008015 195 0.061
positive regulation of camp mediated signaling GO:0043950 3 0.061
transepithelial chloride transport GO:0030321 4 0.060
purine nucleotide metabolic process GO:0006163 302 0.059
actin cytoskeleton organization GO:0030036 220 0.059
regulation of cytokine biosynthetic process GO:0042035 59 0.059
Mouse
lipid transport GO:0006869 98 0.059
positive regulation of protein modification process GO:0031401 299 0.059
Mouse
tissue homeostasis GO:0001894 115 0.059
Mouse
carbohydrate derivative biosynthetic process GO:1901137 183 0.059
positive regulation of homeostatic process GO:0032846 64 0.058
positive regulation of map kinase activity GO:0043406 84 0.058
Mouse
regulation of tumor necrosis factor biosynthetic process GO:0042534 10 0.058
Mouse
regulation of nucleotide metabolic process GO:0006140 169 0.057
regulation of purine nucleotide biosynthetic process GO:1900371 34 0.056
leukocyte activation involved in immune response GO:0002366 126 0.056
Mouse
interleukin 18 production GO:0032621 4 0.056
Mouse
response to extracellular stimulus GO:0009991 127 0.055
purine containing compound metabolic process GO:0072521 311 0.055
negative regulation of immune system process GO:0002683 209 0.054
phospholipase c activating g protein coupled receptor signaling pathway GO:0007200 26 0.054
regulation of protein kinase activity GO:0045859 232 0.054
Mouse
positive regulation of tumor necrosis factor superfamily cytokine production GO:1903557 31 0.054
Mouse
reactive oxygen species biosynthetic process GO:1903409 8 0.053
nucleotide metabolic process GO:0009117 332 0.053
ribonucleotide metabolic process GO:0009259 291 0.053
response to defense related nitric oxide production by other organism involved in symbiotic interaction GO:0052551 2 0.053
Mouse
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger GO:0007187 55 0.052
positive regulation of protein phosphorylation GO:0001934 242 0.052
Mouse
blood vessel morphogenesis GO:0048514 285 0.051
nucleobase containing small molecule metabolic process GO:0055086 352 0.051
organophosphate biosynthetic process GO:0090407 122 0.051
negative regulation of phosphorus metabolic process GO:0010563 184 0.051
Mouse
positive regulation of cytosolic calcium ion concentration GO:0007204 65 0.050
purine nucleotide biosynthetic process GO:0006164 65 0.050
t cell proliferation GO:0042098 120 0.050
regulation of ion homeostasis GO:2000021 64 0.049
positive regulation of cell death GO:0010942 224 0.049
ribonucleotide biosynthetic process GO:0009260 59 0.049
endocytosis GO:0006897 168 0.048
leukocyte mediated immunity GO:0002443 174 0.048
anatomical structure homeostasis GO:0060249 145 0.048
Mouse
activation of mapk activity GO:0000187 59 0.048
Mouse
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.048
Mouse
alpha beta t cell activation GO:0046631 91 0.048
regulation of mapk cascade GO:0043408 248 0.047
Mouse
regulation of purine nucleotide metabolic process GO:1900542 169 0.046
forebrain development GO:0030900 302 0.046
cellular homeostasis GO:0019725 240 0.046
regulation of b cell activation GO:0050864 81 0.046
Mouse
ras protein signal transduction GO:0007265 77 0.046
cellular response to organonitrogen compound GO:0071417 145 0.045
Mouse
regulation of blood pressure GO:0008217 93 0.044
divalent metal ion transport GO:0070838 172 0.044
small gtpase mediated signal transduction GO:0007264 97 0.044
positive regulation of protein transport GO:0051222 93 0.044
Mouse
cellular response to extracellular stimulus GO:0031668 81 0.044
negative regulation of inflammatory response GO:0050728 61 0.043
response to defenses of other organism involved in symbiotic interaction GO:0052173 3 0.043
Mouse
interleukin 1 production GO:0032612 31 0.043
Mouse
regulation of system process GO:0044057 200 0.043
regulation of response to wounding GO:1903034 189 0.042
Mouse
response to radiation GO:0009314 165 0.042
negative regulation of homeostatic process GO:0032845 71 0.042
innate immune response activating signal transduction GO:0002758 50 0.041
Human Mouse
response to peptide GO:1901652 136 0.041
regulation of kinase activity GO:0043549 249 0.041
Mouse
regulation of leukocyte mediated immunity GO:0002703 104 0.041
coagulation GO:0050817 78 0.041
Mouse
nucleotide biosynthetic process GO:0009165 78 0.041
regulation of interferon beta biosynthetic process GO:0045357 4 0.040
Mouse
rho protein signal transduction GO:0007266 32 0.040
negative regulation of phosphate metabolic process GO:0045936 184 0.039
Mouse
oxidation reduction process GO:0055114 342 0.039
sequestering of metal ion GO:0051238 19 0.039
immune response activating cell surface receptor signaling pathway GO:0002429 72 0.039
Mouse
production of molecular mediator of immune response GO:0002440 103 0.039
Mouse
cellular amino acid metabolic process GO:0006520 103 0.039
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.039
cellular lipid metabolic process GO:0044255 323 0.039
myeloid leukocyte activation GO:0002274 83 0.039
somatotropin secreting cell differentiation GO:0060126 4 0.039
membrane organization GO:0061024 245 0.038
positive regulation of lymphocyte activation GO:0051251 140 0.038
Mouse
sequestering of calcium ion GO:0051208 18 0.038
actin filament organization GO:0007015 113 0.038
regulation of vesicle mediated transport GO:0060627 139 0.038
positive regulation of hydrolase activity GO:0051345 148 0.038
myeloid leukocyte differentiation GO:0002573 119 0.038
purine ribonucleotide biosynthetic process GO:0009152 59 0.038
regulation of feeding behavior GO:0060259 3 0.037
carbohydrate transport GO:0008643 62 0.037
regulation of lymphocyte mediated immunity GO:0002706 84 0.037
negative regulation of secretion GO:0051048 61 0.037
immune response regulating cell surface receptor signaling pathway GO:0002768 80 0.037
Mouse
regulation of cell motility GO:2000145 236 0.037
Mouse
positive regulation of protein secretion GO:0050714 52 0.037
Mouse
wound healing GO:0042060 157 0.037
Mouse
cellular response to cytokine stimulus GO:0071345 189 0.037
cytosolic calcium ion homeostasis GO:0051480 70 0.037
aromatic compound catabolic process GO:0019439 286 0.036
response to lipopolysaccharide GO:0032496 128 0.036
Mouse
digestion GO:0007586 40 0.036
Mouse
dendritic cell differentiation GO:0097028 26 0.036
regulation of adaptive immune response GO:0002819 90 0.036
t cell differentiation GO:0030217 174 0.036
leukocyte proliferation GO:0070661 172 0.036
Mouse
carbohydrate metabolic process GO:0005975 230 0.036
regulation of hemostasis GO:1900046 28 0.035
Mouse
multicellular organismal homeostasis GO:0048871 164 0.035
Mouse
cytokine metabolic process GO:0042107 71 0.035
Mouse
positive regulation of cytokine secretion GO:0050715 41 0.035
Mouse
action potential GO:0001508 78 0.035
modulation by symbiont of host immune response GO:0052553 1 0.035
Mouse
nitrogen compound transport GO:0071705 271 0.034
lymphocyte differentiation GO:0030098 242 0.034
response to peptide hormone GO:0043434 127 0.034
positive regulation of nucleotide metabolic process GO:0045981 114 0.034
macromolecule catabolic process GO:0009057 281 0.034
cytokine mediated signaling pathway GO:0019221 115 0.034
regulation of b cell proliferation GO:0030888 39 0.034
Mouse
negative regulation of cellular protein metabolic process GO:0032269 247 0.033
organic cyclic compound catabolic process GO:1901361 295 0.033
regulation of innate immune response GO:0045088 91 0.033
Human Mouse
cytoplasmic transport GO:0016482 234 0.032
inorganic cation transmembrane transport GO:0098662 207 0.032
peptide secretion GO:0002790 114 0.032
regulation of endocytosis GO:0030100 69 0.032
cellular divalent inorganic cation homeostasis GO:0072503 127 0.032
heterocycle catabolic process GO:0046700 280 0.032
regulation of interleukin 8 production GO:0032677 3 0.031
Human
regulation of organelle organization GO:0033043 289 0.031
inorganic ion transmembrane transport GO:0098660 234 0.031
glycoprotein metabolic process GO:0009100 116 0.031
regulation of nucleotide binding oligomerization domain containing 1 signaling pathway GO:0070428 3 0.031
Mouse
b cell proliferation GO:0042100 53 0.031
Mouse
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.031
blood coagulation GO:0007596 76 0.031
Mouse
cell activation involved in immune response GO:0002263 126 0.031
Mouse
striated muscle cell development GO:0055002 125 0.031
organic anion transport GO:0015711 137 0.031
positive regulation of interleukin 12 production GO:0032735 21 0.031
Mouse
positive regulation of stress activated mapk cascade GO:0032874 48 0.031
Mouse
sulfur compound metabolic process GO:0006790 100 0.031
sensory perception GO:0007600 245 0.030
cellular macromolecule catabolic process GO:0044265 206 0.030
anion transport GO:0006820 177 0.030
positive regulation of cell migration GO:0030335 109 0.030
Mouse
activation of innate immune response GO:0002218 56 0.030
Human Mouse
monocarboxylic acid metabolic process GO:0032787 191 0.030
heart process GO:0003015 94 0.030
circulatory system process GO:0003013 197 0.030
negative regulation of protein metabolic process GO:0051248 282 0.030
b cell activation GO:0042113 161 0.030
Mouse
regulation of protein secretion GO:0050708 82 0.029
Mouse
positive regulation of cd8 positive alpha beta t cell extravasation GO:2000451 2 0.028
positive regulation of leukocyte proliferation GO:0070665 73 0.028
Mouse
regulation of homeostatic process GO:0032844 182 0.028
negative regulation of interferon gamma production GO:0032689 18 0.028
Mouse
gland development GO:0048732 330 0.028
negative regulation of cytokine production GO:0001818 84 0.028
Mouse
regulation of t cell activation GO:0050863 170 0.028
reactive oxygen species metabolic process GO:0072593 84 0.028
ameboidal type cell migration GO:0001667 128 0.028
extrinsic apoptotic signaling pathway GO:0097191 126 0.027
cellular response to biotic stimulus GO:0071216 92 0.027
Mouse
modification by symbiont of host morphology or physiology GO:0044003 4 0.027
Mouse
cyclic nucleotide metabolic process GO:0009187 59 0.027
male gamete generation GO:0048232 285 0.027
positive regulation of protein kinase activity GO:0045860 144 0.026
Mouse
regulation of t cell proliferation GO:0042129 92 0.026
camp biosynthetic process GO:0006171 31 0.026
cellular response to molecule of bacterial origin GO:0071219 83 0.026
Mouse
regulation of cellular amino acid metabolic process GO:0006521 5 0.026
positive regulation of production of molecular mediator of immune response GO:0002702 45 0.026
Mouse
positive regulation of interleukin 8 production GO:0032757 2 0.026
Human
apoptotic signaling pathway GO:0097190 306 0.026
cation transmembrane transport GO:0098655 266 0.026
dna metabolic process GO:0006259 303 0.025
organic hydroxy compound biosynthetic process GO:1901617 77 0.025
amide transport GO:0042886 138 0.025
regulation of intracellular transport GO:0032386 159 0.025
t cell extravasation GO:0072683 4 0.025
purine nucleoside triphosphate catabolic process GO:0009146 203 0.025
spermatogenesis GO:0007283 284 0.025
response to insulin GO:0032868 100 0.025
regulation of lipid transport GO:0032368 36 0.025
muscle cell development GO:0055001 133 0.025
regulation of cytokine production involved in immune response GO:0002718 26 0.024
Mouse
cd8 positive alpha beta t cell extravasation GO:0035697 3 0.024
response to drug GO:0042493 75 0.024
Mouse
acetate ester transport GO:1901374 2 0.024
angiogenesis GO:0001525 201 0.024
regulation of heart contraction GO:0008016 77 0.024
organonitrogen compound biosynthetic process GO:1901566 192 0.024
regulation of cellular response to stress GO:0080135 159 0.024
Mouse
calcium ion transport GO:0006816 159 0.024
positive regulation of macrophage cytokine production GO:0060907 7 0.024
Mouse
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.024
tumor necrosis factor superfamily cytokine production GO:0071706 51 0.024
Mouse
vascular process in circulatory system GO:0003018 62 0.024
interleukin 8 production GO:0032637 4 0.024
Human
somatotropin secreting cell development GO:0060133 2 0.024
regulation of myeloid cell differentiation GO:0045637 96 0.024
cyclic purine nucleotide metabolic process GO:0052652 43 0.024
negative regulation of cell activation GO:0050866 111 0.024
lipid biosynthetic process GO:0008610 179 0.024
digestive tract development GO:0048565 190 0.023
muscle tissue development GO:0060537 308 0.023
positive regulation of immune effector process GO:0002699 107 0.023
Mouse
positive regulation of jnk cascade GO:0046330 46 0.023
Mouse
regulation of stress activated mapk cascade GO:0032872 69 0.023
Mouse
ribose phosphate biosynthetic process GO:0046390 59 0.023
negative regulation of erk1 and erk2 cascade GO:0070373 21 0.023
Mouse
positive regulation of transferase activity GO:0051347 167 0.023
Mouse
regulation of hormone secretion GO:0046883 88 0.023
regulation of tumor necrosis factor superfamily cytokine production GO:1903555 50 0.023
Mouse
adaptive immune response GO:0002250 155 0.023
embryonic placenta development GO:0001892 98 0.023
regulation of blood circulation GO:1903522 93 0.023
negative regulation of camp mediated signaling GO:0043951 3 0.023
protein localization to organelle GO:0033365 185 0.023
cellular protein complex assembly GO:0043623 116 0.023
positive regulation of interleukin 18 production GO:0032741 2 0.023
Mouse
regulation of transferase activity GO:0051338 263 0.023
Mouse
positive regulation of leukocyte mediated immunity GO:0002705 70 0.022
adenylate cyclase inhibiting g protein coupled receptor signaling pathway GO:0007193 20 0.022
tissue remodeling GO:0048771 102 0.022
positive regulation of ion transport GO:0043270 65 0.022
lymphocyte activation involved in immune response GO:0002285 93 0.022
Mouse
response to nutrient levels GO:0031667 109 0.022
regulation of leukocyte differentiation GO:1902105 159 0.022
interleukin 6 production GO:0032635 58 0.022
Mouse
positive regulation of apoptotic process GO:0043065 217 0.022
keratinocyte migration GO:0051546 3 0.022
leukocyte apoptotic process GO:0071887 71 0.022
phagocytosis GO:0006909 66 0.022
defense response to gram positive bacterium GO:0050830 50 0.022
Mouse
striated muscle tissue development GO:0014706 293 0.022
response to host defenses GO:0052200 3 0.022
Mouse
response to organic cyclic compound GO:0014070 198 0.022
antigen receptor mediated signaling pathway GO:0050851 64 0.022
lymphocyte mediated immunity GO:0002449 139 0.022
leukocyte migration GO:0050900 124 0.021
Mouse
purine ribonucleoside catabolic process GO:0046130 205 0.021
acid secretion GO:0046717 33 0.021
neural precursor cell proliferation GO:0061351 121 0.021
regulation of angiogenesis GO:0045765 81 0.021
homeostasis of number of cells GO:0048872 210 0.021
positive regulation of cell motility GO:2000147 116 0.021
Mouse
potassium ion transmembrane transport GO:0071805 43 0.021
inflammatory response GO:0006954 244 0.021
Mouse
positive regulation of programmed cell death GO:0043068 218 0.021
regulation of production of molecular mediator of immune response GO:0002700 65 0.021
Mouse
peptide transport GO:0015833 133 0.020
nuclear division GO:0000280 158 0.020
placenta development GO:0001890 140 0.020
cellular response to hormone stimulus GO:0032870 150 0.020
regulation of cytoplasmic transport GO:1903649 112 0.020
ribonucleoside catabolic process GO:0042454 206 0.020
organic acid transport GO:0015849 101 0.020
positive regulation of gtp catabolic process GO:0033126 85 0.020
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 87 0.020
meiotic nuclear division GO:0007126 115 0.020
glycerolipid metabolic process GO:0046486 122 0.020
positive regulation of lymphocyte proliferation GO:0050671 70 0.020
Mouse
regulation of neurotransmitter levels GO:0001505 87 0.020
organic hydroxy compound metabolic process GO:1901615 203 0.020
regulation of purine nucleotide catabolic process GO:0033121 122 0.019
regulation of cellular catabolic process GO:0031329 242 0.019
positive regulation by symbiont of host immune response GO:0052556 1 0.019
Mouse
regulation of ras protein signal transduction GO:0046578 114 0.019
positive regulation of endopeptidase activity GO:0010950 43 0.019
ribonucleoside triphosphate metabolic process GO:0009199 220 0.019
hormone secretion GO:0046879 128 0.019
glycoprotein biosynthetic process GO:0009101 89 0.019
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.019
regulation of neuron differentiation GO:0045664 281 0.019
positive regulation of cellular catabolic process GO:0031331 148 0.019
modulation by organism of defense related nitric oxide production in other organism involved in symbiotic interaction GO:0052302 1 0.019
Mouse
regulation of hormone levels GO:0010817 211 0.019
negative regulation of lymphocyte proliferation GO:0050672 45 0.019
humoral immune response GO:0006959 57 0.019
positive regulation of intracellular estrogen receptor signaling pathway GO:0033148 4 0.019
cell adhesion GO:0007155 329 0.019
positive regulation of reactive oxygen species metabolic process GO:2000379 11 0.019
negative regulation of phosphorylation GO:0042326 166 0.019
Mouse
regulation of ossification GO:0030278 112 0.019
nucleotide catabolic process GO:0009166 217 0.019
t cell differentiation in thymus GO:0033077 77 0.019
multicellular organismal signaling GO:0035637 91 0.018
jnk cascade GO:0007254 72 0.018
Mouse
myeloid cell apoptotic process GO:0033028 22 0.018
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.018
multi multicellular organism process GO:0044706 109 0.018
endocrine hormone secretion GO:0060986 15 0.018
regulation of ion transmembrane transport GO:0034765 119 0.018
regulation of multi organism process GO:0043900 111 0.018
Mouse
cell surface pattern recognition receptor signaling pathway GO:0002752 2 0.018
Mouse
regulation of fat cell differentiation GO:0045598 81 0.018
chemokine production GO:0032602 34 0.018
Mouse
general adaptation syndrome GO:0051866 2 0.018
nucleoside catabolic process GO:0009164 206 0.018
chemotaxis GO:0006935 247 0.018
positive regulation of phospholipase activity GO:0010518 3 0.018
cyclic nucleotide biosynthetic process GO:0009190 44 0.018
regulation of reactive oxygen species metabolic process GO:2000377 40 0.018
negative regulation of secretion by cell GO:1903531 54 0.018
heart contraction GO:0060047 93 0.018
negative regulation of response to wounding GO:1903035 77 0.017
interferon gamma production GO:0032609 67 0.017
Mouse
positive regulation of cyclic nucleotide biosynthetic process GO:0030804 24 0.017
myeloid dendritic cell activation GO:0001773 25 0.017
organelle fission GO:0048285 170 0.017
regulation of tube size GO:0035150 57 0.017
tissue migration GO:0090130 68 0.017
glycosyl compound catabolic process GO:1901658 206 0.017
purine nucleoside metabolic process GO:0042278 241 0.017
regulation of cytoskeleton organization GO:0051493 122 0.017
organelle assembly GO:0070925 177 0.017
ribonucleoside metabolic process GO:0009119 245 0.017
regulation of cell projection organization GO:0031344 206 0.017
positive regulation of growth GO:0045927 104 0.017
regulation of transmembrane transport GO:0034762 128 0.017
positive regulation of lymphocyte mediated immunity GO:0002708 62 0.017
regulation of blood vessel size GO:0050880 56 0.017
cellular response to insulin stimulus GO:0032869 78 0.017
camp metabolic process GO:0046058 40 0.017
positive regulation of proteolysis GO:0045862 85 0.017
release of sequestered calcium ion into cytosol GO:0051209 42 0.017
developmental maturation GO:0021700 193 0.017
interleukin 17 production GO:0032620 11 0.017
Mouse
nucleoside phosphate biosynthetic process GO:1901293 79 0.017
response to light stimulus GO:0009416 135 0.017
cellular nitrogen compound catabolic process GO:0044270 280 0.017
spermatid development GO:0007286 108 0.017
dipeptide transport GO:0042938 2 0.017
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.017
regulation of hydrolase activity GO:0051336 246 0.016
sperm ejaculation GO:0042713 1 0.016
cellular response to bacterial lipoprotein GO:0071220 3 0.016
Mouse
positive regulation of interferon gamma production GO:0032729 39 0.016
Mouse
regulation of macrophage cytokine production GO:0010935 8 0.016
Mouse
regulation of coagulation GO:0050818 31 0.016
Mouse
platelet activation GO:0030168 40 0.016
Mouse
negative regulation of lymphocyte activation GO:0051250 91 0.016
negative regulation of protein transport GO:0051224 46 0.016
nucleoside triphosphate catabolic process GO:0009143 205 0.016
regulation of antigen receptor mediated signaling pathway GO:0050854 29 0.016
negative regulation of cellular component organization GO:0051129 194 0.016
negative regulation of immune effector process GO:0002698 55 0.016
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.016
hindbrain formation GO:0021576 1 0.016
negative regulation of hormone biosynthetic process GO:0032353 4 0.016
integrin mediated signaling pathway GO:0007229 27 0.016
nucleoside triphosphate metabolic process GO:0009141 230 0.016
regulation of cysteine type endopeptidase activity GO:2000116 65 0.016
regulation of nucleoside metabolic process GO:0009118 130 0.016
locomotory behavior GO:0007626 195 0.016
regulation of t cell differentiation GO:0045580 83 0.016
regulation of vasculature development GO:1901342 88 0.016
digestive system development GO:0055123 200 0.016
nucleoside phosphate catabolic process GO:1901292 222 0.016
regulation of blood coagulation GO:0030193 28 0.016
Mouse
rhythmic process GO:0048511 174 0.016
positive regulation of ras gtpase activity GO:0032320 65 0.016
regulation of acute inflammatory response GO:0002673 27 0.015
wnt signaling pathway GO:0016055 188 0.015
cell substrate adhesion GO:0031589 130 0.015
regulation of lipid metabolic process GO:0019216 118 0.015
circadian rhythm GO:0007623 114 0.015
purine ribonucleoside metabolic process GO:0046128 241 0.015
cellular response to peptide GO:1901653 92 0.015
axonogenesis GO:0007409 274 0.015
bone resorption GO:0045453 38 0.015
positive regulation of organelle organization GO:0010638 128 0.015
regulation of nucleotide catabolic process GO:0030811 122 0.015
regulation of reproductive process GO:2000241 66 0.015
organophosphate catabolic process GO:0046434 232 0.015
lymphocyte apoptotic process GO:0070227 54 0.015
nitric oxide biosynthetic process GO:0006809 25 0.015
Mouse
negative regulation of cell proliferation GO:0008285 296 0.015
regulation of myeloid leukocyte differentiation GO:0002761 58 0.015
learning or memory GO:0007611 148 0.015
peptidyl tyrosine modification GO:0018212 145 0.015
cardiac chamber morphogenesis GO:0003206 93 0.015
response to acid chemical GO:0001101 111 0.015
positive regulation of t cell activation GO:0050870 101 0.015
cardiac muscle tissue development GO:0048738 130 0.015
positive regulation by symbiont of host defense response GO:0052509 1 0.015
Mouse
synapse organization GO:0050808 125 0.015
regulation of cellular carbohydrate metabolic process GO:0010675 75 0.015
cellular response to acid chemical GO:0071229 68 0.015
neuronal action potential GO:0019228 54 0.015
regulation of cd8 positive alpha beta t cell extravasation GO:2000449 3 0.015

Tlr5 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.026
Human
nervous system disease DOID:863 0 0.026
musculoskeletal system disease DOID:17 0 0.019
Human
sensory system disease DOID:0050155 0 0.017
eye and adnexa disease DOID:1492 0 0.017