Mus musculus

235 known processes

Whsc1

Wolf-Hirschhorn syndrome candidate 1 (human)

(Aliases: 5830445G22Rik,C130020C13Rik,Whsc1l,D930023B08Rik,9430010A17Rik,D030027O06Rik,mKIAA1090,AW555663)

Whsc1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
microtubule based process GO:0007017 236 0.384
organelle fission GO:0048285 170 0.326
protein dna complex disassembly GO:0032986 1 0.324
nucleosome disassembly GO:0006337 1 0.317
chromatin disassembly GO:0031498 1 0.293
nuclear division GO:0000280 158 0.275
germ cell development GO:0007281 185 0.249
meiotic cell cycle GO:0051321 122 0.227
chromatin organization GO:0006325 206 0.205
regulation of cell cycle process GO:0010564 160 0.163
cellular amino acid metabolic process GO:0006520 103 0.160
regulation of cell cycle GO:0051726 281 0.144
regulation of organelle organization GO:0033043 289 0.141
methylation GO:0032259 134 0.140
regionalization GO:0003002 337 0.138
male gamete generation GO:0048232 285 0.132
meiotic nuclear division GO:0007126 115 0.119
spermatid differentiation GO:0048515 115 0.118
cell division GO:0051301 120 0.115
organelle assembly GO:0070925 177 0.110
positive regulation of cellular amine metabolic process GO:0033240 5 0.106
peptidyl amino acid modification GO:0018193 336 0.101
regulation of cell cycle g2 m phase transition GO:1902749 10 0.099
mitotic cell cycle process GO:1903047 159 0.098
microtubule cytoskeleton organization GO:0000226 157 0.093
protein methylation GO:0006479 81 0.091
macromolecule methylation GO:0043414 120 0.085
spermatogenesis GO:0007283 284 0.083
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.082
protein alkylation GO:0008213 81 0.077
dna metabolic process GO:0006259 303 0.076
cellular amine metabolic process GO:0044106 44 0.075
regulation of cellular amino acid metabolic process GO:0006521 5 0.071
regulation of cellular amine metabolic process GO:0033238 20 0.068
peptidyl lysine modification GO:0018205 77 0.065
negative regulation of protein metabolic process GO:0051248 282 0.064
cellular response to dna damage stimulus GO:0006974 207 0.063
cilium morphogenesis GO:0060271 102 0.054
amine metabolic process GO:0009308 45 0.053
regulation of cellular ketone metabolic process GO:0010565 66 0.049
protein complex disassembly GO:0043241 40 0.047
pole plasm assembly GO:0007315 2 0.047
protein maturation GO:0051604 176 0.046
maintenance of location GO:0051235 89 0.045
regulation of nuclear division GO:0051783 56 0.045
positive regulation of organelle organization GO:0010638 128 0.042
regulation of meiotic cell cycle GO:0051445 34 0.042
chromatin modification GO:0016568 187 0.041
cellular nitrogen compound catabolic process GO:0044270 280 0.041
spermatid development GO:0007286 108 0.041
protein dna complex subunit organization GO:0071824 28 0.041
heterocycle catabolic process GO:0046700 280 0.041
meiotic cell cycle process GO:1903046 77 0.041
mitotic cell cycle GO:0000278 195 0.040
histone modification GO:0016570 159 0.040
organic cyclic compound catabolic process GO:1901361 295 0.039
lipid biosynthetic process GO:0008610 179 0.039
nitrogen compound transport GO:0071705 271 0.039
nucleobase containing small molecule metabolic process GO:0055086 352 0.038
regulation of cell cycle phase transition GO:1901987 77 0.037
translation GO:0006412 93 0.037
macromolecular complex disassembly GO:0032984 43 0.037
apoptotic signaling pathway GO:0097190 306 0.037
skin development GO:0043588 220 0.036
protein acylation GO:0043543 64 0.036
small gtpase mediated signal transduction GO:0007264 97 0.036
blastocyst development GO:0001824 80 0.036
intracellular protein transport GO:0006886 204 0.035
regulation of mitotic cell cycle phase transition GO:1901990 73 0.034
macromolecule catabolic process GO:0009057 281 0.034
protein catabolic process GO:0030163 221 0.033
receptor mediated endocytosis GO:0006898 51 0.032
epidermis development GO:0008544 187 0.032
protein modification by small protein conjugation or removal GO:0070647 207 0.032
g1 s transition of mitotic cell cycle GO:0000082 57 0.031
cellular ketone metabolic process GO:0042180 84 0.031
negative regulation of cell cycle GO:0045786 123 0.031
positive regulation of lymphocyte activation GO:0051251 140 0.030
protein import into nucleus GO:0006606 95 0.030
cellular lipid metabolic process GO:0044255 323 0.029
muscle cell differentiation GO:0042692 261 0.029
negative regulation of cellular component organization GO:0051129 194 0.028
retina development in camera type eye GO:0060041 119 0.028
regulation of cellular component biogenesis GO:0044087 181 0.027
internal peptidyl lysine acetylation GO:0018393 42 0.027
regulation of mitotic cell cycle GO:0007346 126 0.027
nucleoside triphosphate catabolic process GO:0009143 205 0.027
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.027
regulation of cell division GO:0051302 76 0.027
endocytosis GO:0006897 168 0.027
regulation of multi organism process GO:0043900 111 0.027
negative regulation of gene expression epigenetic GO:0045814 15 0.027
ribonucleoside triphosphate catabolic process GO:0009203 199 0.027
meiosis i GO:0007127 60 0.026
genitalia development GO:0048806 37 0.026
negative regulation of cellular protein metabolic process GO:0032269 247 0.026
negative regulation of cell cycle phase transition GO:1901988 48 0.026
cilium assembly GO:0042384 81 0.026
purine nucleotide catabolic process GO:0006195 211 0.026
forebrain development GO:0030900 302 0.025
gonad development GO:0008406 141 0.025
regulation of protein complex assembly GO:0043254 83 0.025
hatching GO:0035188 4 0.025
regulation of microtubule based process GO:0032886 52 0.025
regulation of cell activation GO:0050865 289 0.025
protein ubiquitination GO:0016567 171 0.025
protein modification by small protein conjugation GO:0032446 187 0.025
male meiosis GO:0007140 37 0.025
ribonucleotide catabolic process GO:0009261 208 0.024
female gamete generation GO:0007292 74 0.024
nuclear transport GO:0051169 139 0.024
posttranscriptional regulation of gene expression GO:0010608 155 0.024
positive regulation of cell cycle GO:0045787 92 0.024
positive regulation of mitotic cell cycle GO:0045931 41 0.024
glycosyl compound catabolic process GO:1901658 206 0.024
organophosphate catabolic process GO:0046434 232 0.024
histone acetylation GO:0016573 41 0.023
ribose phosphate metabolic process GO:0019693 291 0.023
oocyte construction GO:0007308 2 0.023
protein import GO:0017038 101 0.023
b cell activation GO:0042113 161 0.023
response to lipopolysaccharide GO:0032496 128 0.023
purine nucleoside triphosphate catabolic process GO:0009146 203 0.023
purine nucleoside catabolic process GO:0006152 205 0.023
purine nucleoside metabolic process GO:0042278 241 0.023
mitotic sister chromatid segregation GO:0000070 14 0.022
lateral inhibition GO:0046331 1 0.022
nucleocytoplasmic transport GO:0006913 139 0.022
epithelial cell development GO:0002064 159 0.022
sister chromatid segregation GO:0000819 20 0.022
cellular component assembly involved in morphogenesis GO:0010927 139 0.022
ossification GO:0001503 216 0.022
cell type specific apoptotic process GO:0097285 268 0.021
development of primary sexual characteristics GO:0045137 143 0.021
rna interference GO:0016246 2 0.021
cellular macromolecule catabolic process GO:0044265 206 0.021
purine nucleotide metabolic process GO:0006163 302 0.021
cellular response to organonitrogen compound GO:0071417 145 0.021
organonitrogen compound catabolic process GO:1901565 264 0.021
oxidation reduction process GO:0055114 342 0.021
nucleoside metabolic process GO:0009116 246 0.021
nucleoside catabolic process GO:0009164 206 0.021
aromatic compound catabolic process GO:0019439 286 0.020
compound eye development GO:0048749 1 0.020
cell adhesion GO:0007155 329 0.020
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.020
protein palmitoylation GO:0018345 14 0.020
regulation of chromosome organization GO:0033044 83 0.020
inflammatory response GO:0006954 244 0.020
neuron apoptotic process GO:0051402 142 0.020
purine containing compound catabolic process GO:0072523 213 0.020
lipid localization GO:0010876 126 0.019
response to oxidative stress GO:0006979 123 0.019
chromosome segregation GO:0007059 48 0.019
cellular response to hormone stimulus GO:0032870 150 0.019
ion transmembrane transport GO:0034220 361 0.019
rna processing GO:0006396 105 0.019
negative regulation of cell proliferation GO:0008285 296 0.019
cytoplasmic transport GO:0016482 234 0.019
peptidyl lysine acetylation GO:0018394 45 0.019
organelle localization GO:0051640 179 0.019
protein polymerization GO:0051258 57 0.019
nucleoside triphosphate metabolic process GO:0009141 230 0.019
ribonucleoside triphosphate metabolic process GO:0009199 220 0.019
sensory organ morphogenesis GO:0090596 242 0.018
glycosyl compound metabolic process GO:1901657 246 0.018
regulation of chromatin modification GO:1903308 57 0.018
double strand break repair GO:0006302 48 0.018
ras protein signal transduction GO:0007265 77 0.018
organic hydroxy compound metabolic process GO:1901615 203 0.018
regulation of secretion GO:0051046 274 0.018
regulation of cellular catabolic process GO:0031329 242 0.018
gene silencing GO:0016458 38 0.018
histone methylation GO:0016571 71 0.018
microtubule organizing center organization GO:0031023 28 0.018
protein targeting GO:0006605 143 0.018
purine ribonucleotide catabolic process GO:0009154 208 0.018
response to insulin GO:0032868 100 0.018
regulation of response to wounding GO:1903034 189 0.018
transmembrane transport GO:0055085 412 0.018
establishment of organelle localization GO:0051656 122 0.018
body morphogenesis GO:0010171 45 0.017
regulation of fat cell differentiation GO:0045598 81 0.017
regulation of lymphocyte activation GO:0051249 240 0.017
regulation of nucleoside metabolic process GO:0009118 130 0.017
purine containing compound metabolic process GO:0072521 311 0.017
positive regulation of mitotic cell cycle phase transition GO:1901992 17 0.017
positive regulation of protein modification process GO:0031401 299 0.017
regulation of hormone levels GO:0010817 211 0.017
multicellular organismal signaling GO:0035637 91 0.017
single organism nuclear import GO:1902593 95 0.017
purine nucleoside triphosphate metabolic process GO:0009144 226 0.017
nucleoside phosphate metabolic process GO:0006753 338 0.017
regulation of histone h3 k36 methylation GO:0000414 1 0.017
regulation of mrna processing GO:0050684 41 0.017
regulation of rna splicing GO:0043484 37 0.017
lymphocyte proliferation GO:0046651 164 0.017
oogenesis GO:0048477 56 0.017
nucleotide metabolic process GO:0009117 332 0.017
regulation of lymphocyte proliferation GO:0050670 117 0.017
nucleoside phosphate catabolic process GO:1901292 222 0.017
ubiquitin dependent protein catabolic process GO:0006511 129 0.016
membrane organization GO:0061024 245 0.016
carbohydrate derivative catabolic process GO:1901136 231 0.016
response to peptide hormone GO:0043434 127 0.016
positive regulation of cell cycle phase transition GO:1901989 17 0.016
purine ribonucleoside metabolic process GO:0046128 241 0.016
negative regulation of organelle organization GO:0010639 90 0.016
negative regulation of cell cycle process GO:0010948 69 0.016
developmental maturation GO:0021700 193 0.016
nucleotide catabolic process GO:0009166 217 0.016
regulation of transferase activity GO:0051338 263 0.016
positive regulation of cell activation GO:0050867 158 0.016
negative regulation of protein modification process GO:0031400 163 0.016
chromatin assembly or disassembly GO:0006333 16 0.016
maternal determination of anterior posterior axis embryo GO:0008358 2 0.015
negative regulation of cellular amine metabolic process GO:0033239 1 0.015
covalent chromatin modification GO:0016569 163 0.015
regulation of apoptotic signaling pathway GO:2001233 197 0.015
response to peptide GO:1901652 136 0.015
carbohydrate derivative biosynthetic process GO:1901137 183 0.015
regulation of cytoskeleton organization GO:0051493 122 0.015
oocyte axis specification GO:0007309 2 0.015
cellular protein catabolic process GO:0044257 155 0.015
rna stabilization GO:0043489 9 0.015
interspecies interaction between organisms GO:0044419 83 0.015
response to radiation GO:0009314 165 0.015
dna templated transcriptional preinitiation complex assembly GO:0070897 4 0.015
mitotic nuclear division GO:0007067 48 0.015
lipoprotein metabolic process GO:0042157 43 0.015
organonitrogen compound biosynthetic process GO:1901566 192 0.015
regulation of protein maturation GO:1903317 96 0.015
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.015
regulation of intracellular transport GO:0032386 159 0.015
cation transport GO:0006812 399 0.015
spindle assembly involved in female meiosis GO:0007056 3 0.015
spindle assembly involved in meiosis GO:0090306 4 0.014
ribonucleotide metabolic process GO:0009259 291 0.014
establishment of protein localization to organelle GO:0072594 118 0.014
regulation of secretion by cell GO:1903530 249 0.014
amide transport GO:0042886 138 0.014
response to molecule of bacterial origin GO:0002237 143 0.014
regulation of establishment of protein localization GO:0070201 181 0.014
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.014
dna recombination GO:0006310 92 0.014
regulation of leukocyte proliferation GO:0070663 121 0.014
regulation of mrna stability GO:0043488 23 0.013
interaction with symbiont GO:0051702 14 0.013
regulation of cellular response to stress GO:0080135 159 0.013
positive regulation of chromosome organization GO:2001252 33 0.013
rna polymerase ii transcriptional preinitiation complex assembly GO:0051123 3 0.013
positive regulation of cell cycle process GO:0090068 61 0.013
intracellular mrna localization GO:0008298 4 0.013
cytokine production GO:0001816 319 0.013
dendrite development GO:0016358 115 0.013
antimicrobial peptide production GO:0002775 2 0.013
lymphocyte mediated immunity GO:0002449 139 0.013
response to organonitrogen compound GO:0010243 246 0.013
respiratory system development GO:0060541 190 0.013
telencephalon development GO:0021537 186 0.013
neural retina development GO:0003407 41 0.013
neural tube development GO:0021915 160 0.013
regulation of ras protein signal transduction GO:0046578 114 0.013
cell cycle g2 m phase transition GO:0044839 20 0.013
response to inorganic substance GO:0010035 96 0.013
actin cytoskeleton organization GO:0030036 220 0.013
positive regulation of apoptotic process GO:0043065 217 0.013
regulation of protein transport GO:0051223 163 0.013
microtubule polymerization or depolymerization GO:0031109 26 0.013
regulation of inflammatory response GO:0050727 147 0.012
regulation of membrane potential GO:0042391 192 0.012
regulation of cytoplasmic transport GO:1903649 112 0.012
single fertilization GO:0007338 82 0.012
synaptic transmission GO:0007268 329 0.012
organism emergence from protective structure GO:0071684 4 0.012
camera type eye development GO:0043010 266 0.012
positive regulation of transcription elongation from rna polymerase ii promoter GO:0032968 2 0.012
regulation of cell motility GO:2000145 236 0.012
negative regulation of apoptotic signaling pathway GO:2001234 104 0.012
cellular response to transforming growth factor beta stimulus GO:0071560 88 0.012
neuroblast differentiation GO:0014016 2 0.012
inner cell mass cell proliferation GO:0001833 15 0.012
mitotic cytokinesis GO:0000281 4 0.012
neuroblast fate commitment GO:0014017 1 0.012
negative regulation of proteolysis GO:0045861 74 0.012
neuron death GO:0070997 154 0.012
leukocyte mediated immunity GO:0002443 174 0.012
negative regulation of mitotic cell cycle GO:0045930 58 0.012
leukocyte proliferation GO:0070661 172 0.012
chromatin remodeling GO:0006338 32 0.012
regulation of protein catabolic process GO:0042176 108 0.012
positive regulation of programmed cell death GO:0043068 218 0.011
sensory perception GO:0007600 245 0.011
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 68 0.011
guanosine containing compound catabolic process GO:1901069 144 0.011
spindle organization GO:0007051 28 0.011
immune effector process GO:0002252 321 0.011
response to growth factor GO:0070848 198 0.011
leukocyte differentiation GO:0002521 342 0.011
negative regulation of growth GO:0045926 99 0.011
cellular response to cytokine stimulus GO:0071345 189 0.011
positive regulation of cell development GO:0010720 237 0.011
regulation of purine nucleotide metabolic process GO:1900542 169 0.011
negative regulation of cell development GO:0010721 169 0.011
cell fate commitment GO:0045165 210 0.011
cell maturation GO:0048469 127 0.011
negative regulation of protein processing GO:0010955 79 0.011
dna hypermethylation GO:0044026 3 0.011
alcohol metabolic process GO:0006066 116 0.011
regulation of neuron differentiation GO:0045664 281 0.011
skeletal system development GO:0001501 356 0.011
peptide hormone secretion GO:0030072 109 0.011
axonogenesis GO:0007409 274 0.011
regulation of cytokine production GO:0001817 266 0.011
regulation of t cell activation GO:0050863 170 0.011
regulation of cell migration GO:0030334 219 0.011
g2 m transition of mitotic cell cycle GO:0000086 20 0.011
response to extracellular stimulus GO:0009991 127 0.011
blastocyst growth GO:0001832 23 0.011
negative regulation of intracellular signal transduction GO:1902532 167 0.011
intrinsic apoptotic signaling pathway GO:0097193 132 0.011
modification dependent macromolecule catabolic process GO:0043632 133 0.011
small molecule catabolic process GO:0044282 71 0.011
regulation of cell projection organization GO:0031344 206 0.010
posttranscriptional gene silencing GO:0016441 10 0.010
somatic recombination of immunoglobulin gene segments GO:0016447 42 0.010
digestive tract morphogenesis GO:0048546 147 0.010
Mouse
gland development GO:0048732 330 0.010
symbiosis encompassing mutualism through parasitism GO:0044403 83 0.010
regulation of defense response GO:0031347 233 0.010
nuclear import GO:0051170 95 0.010
carbohydrate metabolic process GO:0005975 230 0.010
cellular response to acid chemical GO:0071229 68 0.010
cellular protein complex assembly GO:0043623 116 0.010
response to light stimulus GO:0009416 135 0.010
mrna metabolic process GO:0016071 84 0.010
action potential GO:0001508 78 0.010
regulation of chromatin organization GO:1902275 57 0.010
modification dependent protein catabolic process GO:0019941 133 0.010
regulation of histone methylation GO:0031060 30 0.010
negative regulation of chromosome organization GO:2001251 30 0.010
mrna catabolic process GO:0006402 22 0.010
protein localization to membrane GO:0072657 108 0.010
locomotory behavior GO:0007626 195 0.010
negative regulation of nervous system development GO:0051961 156 0.010
regulation of gtp catabolic process GO:0033124 113 0.010
stem cell proliferation GO:0072089 117 0.010
purine ribonucleotide metabolic process GO:0009150 290 0.010
cell activation involved in immune response GO:0002263 126 0.010
stem cell fate specification GO:0048866 3 0.010

Whsc1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.039
nervous system disease DOID:863 0 0.039
central nervous system disease DOID:331 0 0.026
disease of cellular proliferation DOID:14566 0 0.012
cancer DOID:162 0 0.012
organ system cancer DOID:0050686 0 0.012
neurodegenerative disease DOID:1289 0 0.012
immune system cancer DOID:0060083 0 0.011
hematologic cancer DOID:2531 0 0.011