Mus musculus

36 known processes

Mtr

5-methyltetrahydrofolate-homocysteine methyltransferase

(Aliases: D830038K18Rik,MS,AI894170)

Mtr biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of cell cycle GO:0051726 281 0.085
male gamete generation GO:0048232 285 0.066
cellular amine metabolic process GO:0044106 44 0.063
cellular amino acid metabolic process GO:0006520 103 0.057
cellular ketone metabolic process GO:0042180 84 0.056
chromatin modification GO:0016568 187 0.055
dna metabolic process GO:0006259 303 0.053
microtubule based process GO:0007017 236 0.052
spermatogenesis GO:0007283 284 0.051
chromatin organization GO:0006325 206 0.048
peptidyl amino acid modification GO:0018193 336 0.047
regulation of cellular ketone metabolic process GO:0010565 66 0.046
response to organonitrogen compound GO:0010243 246 0.045
nuclear division GO:0000280 158 0.045
organelle fission GO:0048285 170 0.044
germ cell development GO:0007281 185 0.040
transmembrane transport GO:0055085 412 0.039
heterocycle catabolic process GO:0046700 280 0.038
purine containing compound metabolic process GO:0072521 311 0.036
regulation of cellular amino acid metabolic process GO:0006521 5 0.035
cellular nitrogen compound catabolic process GO:0044270 280 0.035
meiotic nuclear division GO:0007126 115 0.034
organonitrogen compound catabolic process GO:1901565 264 0.034
covalent chromatin modification GO:0016569 163 0.034
nucleobase containing small molecule metabolic process GO:0055086 352 0.034
apoptotic signaling pathway GO:0097190 306 0.034
camera type eye development GO:0043010 266 0.033
skeletal system development GO:0001501 356 0.032
leukocyte differentiation GO:0002521 342 0.032
intracellular protein transport GO:0006886 204 0.032
ribonucleoside metabolic process GO:0009119 245 0.032
aromatic compound catabolic process GO:0019439 286 0.032
muscle tissue development GO:0060537 308 0.031
carbohydrate derivative catabolic process GO:1901136 231 0.031
purine ribonucleotide metabolic process GO:0009150 290 0.030
ribonucleotide metabolic process GO:0009259 291 0.030
nucleotide metabolic process GO:0009117 332 0.030
ossification GO:0001503 216 0.030
regulation of organelle organization GO:0033043 289 0.029
positive regulation of protein phosphorylation GO:0001934 242 0.029
glycosyl compound metabolic process GO:1901657 246 0.029
positive regulation of protein modification process GO:0031401 299 0.029
purine nucleotide metabolic process GO:0006163 302 0.029
dna repair GO:0006281 107 0.029
microtubule cytoskeleton organization GO:0000226 157 0.028
regulation of cellular amine metabolic process GO:0033238 20 0.028
small gtpase mediated signal transduction GO:0007264 97 0.028
nucleoside phosphate metabolic process GO:0006753 338 0.028
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.027
meiotic cell cycle GO:0051321 122 0.027
ion transmembrane transport GO:0034220 361 0.027
cell adhesion GO:0007155 329 0.026
mitotic cell cycle process GO:1903047 159 0.026
negative regulation of cellular component organization GO:0051129 194 0.025
cytoplasmic transport GO:0016482 234 0.025
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.025
regionalization GO:0003002 337 0.024
cellular lipid metabolic process GO:0044255 323 0.024
nucleoside triphosphate catabolic process GO:0009143 205 0.024
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.024
lymphocyte differentiation GO:0030098 242 0.024
organic cyclic compound catabolic process GO:1901361 295 0.023
regulation of cell cycle process GO:0010564 160 0.023
sensory organ morphogenesis GO:0090596 242 0.023
circulatory system process GO:0003013 197 0.023
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.023
cation transmembrane transport GO:0098655 266 0.023
nucleoside catabolic process GO:0009164 206 0.023
negative regulation of protein metabolic process GO:0051248 282 0.022
nucleoside triphosphate metabolic process GO:0009141 230 0.022
purine nucleoside triphosphate metabolic process GO:0009144 226 0.022
purine ribonucleoside metabolic process GO:0046128 241 0.022
nucleoside phosphate catabolic process GO:1901292 222 0.022
response to lipopolysaccharide GO:0032496 128 0.022
regulation of mapk cascade GO:0043408 248 0.022
placenta development GO:0001890 140 0.022
striated muscle tissue development GO:0014706 293 0.022
wnt signaling pathway GO:0016055 188 0.022
organophosphate catabolic process GO:0046434 232 0.022
respiratory system development GO:0060541 190 0.021
amine metabolic process GO:0009308 45 0.021
organelle assembly GO:0070925 177 0.021
single organismal cell cell adhesion GO:0016337 131 0.021
histone modification GO:0016570 159 0.021
regulation of cytokine production GO:0001817 266 0.021
oxidation reduction process GO:0055114 342 0.021
macromolecule methylation GO:0043414 120 0.021
bone development GO:0060348 120 0.021
positive regulation of cellular amine metabolic process GO:0033240 5 0.021
methylation GO:0032259 134 0.021
blood circulation GO:0008015 195 0.021
nucleotide catabolic process GO:0009166 217 0.021
stem cell differentiation GO:0048863 268 0.021
glycosyl compound catabolic process GO:1901658 206 0.021
cellular response to dna damage stimulus GO:0006974 207 0.021
regulation of apoptotic signaling pathway GO:2001233 197 0.020
oocyte construction GO:0007308 2 0.020
ribonucleoside triphosphate catabolic process GO:0009203 199 0.020
dna recombination GO:0006310 92 0.020
organelle localization GO:0051640 179 0.020
response to molecule of bacterial origin GO:0002237 143 0.020
gonad development GO:0008406 141 0.020
multi multicellular organism process GO:0044706 109 0.020
mapk cascade GO:0000165 281 0.020
protein localization to organelle GO:0033365 185 0.020
single organism cell adhesion GO:0098602 156 0.020
positive regulation of apoptotic process GO:0043065 217 0.020
macromolecule catabolic process GO:0009057 281 0.019
purine ribonucleotide catabolic process GO:0009154 208 0.019
positive regulation of cell death GO:0010942 224 0.019
cellular homeostasis GO:0019725 240 0.019
ribose phosphate metabolic process GO:0019693 291 0.019
skin development GO:0043588 220 0.019
purine nucleotide catabolic process GO:0006195 211 0.019
regulation of cell adhesion GO:0030155 154 0.019
protein modification by small protein conjugation or removal GO:0070647 207 0.019
purine nucleoside triphosphate catabolic process GO:0009146 203 0.019
purine containing compound catabolic process GO:0072523 213 0.019
response to growth factor GO:0070848 198 0.019
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.019
negative regulation of cellular protein metabolic process GO:0032269 247 0.018
blood vessel morphogenesis GO:0048514 285 0.018
embryonic organ morphogenesis GO:0048562 276 0.018
stem cell development GO:0048864 219 0.018
anatomical structure homeostasis GO:0060249 145 0.018
spermatid development GO:0007286 108 0.018
cytokine production GO:0001816 319 0.018
regulation of neuron differentiation GO:0045664 281 0.018
regulation of cell activation GO:0050865 289 0.018
fertilization GO:0009566 127 0.018
neural tube development GO:0021915 160 0.018
positive regulation of programmed cell death GO:0043068 218 0.018
protein maturation GO:0051604 176 0.018
cellular response to growth factor stimulus GO:0071363 197 0.018
negative regulation of cellular amine metabolic process GO:0033239 1 0.018
innate immune response GO:0045087 157 0.018
cilium morphogenesis GO:0060271 102 0.018
compound eye development GO:0048749 1 0.018
blastocyst development GO:0001824 80 0.018
ribonucleoside triphosphate metabolic process GO:0009199 220 0.018
respiratory tube development GO:0030323 167 0.018
heart morphogenesis GO:0003007 178 0.017
rna processing GO:0006396 105 0.017
mitotic cell cycle GO:0000278 195 0.017
retina development in camera type eye GO:0060041 119 0.017
regulation of body fluid levels GO:0050878 162 0.017
regulation of cell projection organization GO:0031344 206 0.017
intrinsic apoptotic signaling pathway GO:0097193 132 0.017
urogenital system development GO:0001655 261 0.017
regulation of anatomical structure size GO:0090066 178 0.017
cellular response to molecule of bacterial origin GO:0071219 83 0.017
muscle cell differentiation GO:0042692 261 0.017
lung development GO:0030324 164 0.017
purine ribonucleoside catabolic process GO:0046130 205 0.017
ear development GO:0043583 200 0.017
cellular response to lipopolysaccharide GO:0071222 77 0.016
skeletal system morphogenesis GO:0048705 203 0.016
nitrogen compound transport GO:0071705 271 0.016
regulation of kinase activity GO:0043549 249 0.016
cell activation involved in immune response GO:0002263 126 0.016
maintenance of location GO:0051235 89 0.016
b cell activation GO:0042113 161 0.016
monocarboxylic acid metabolic process GO:0032787 191 0.016
response to radiation GO:0009314 165 0.016
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.016
negative regulation of cell proliferation GO:0008285 296 0.016
multicellular organismal signaling GO:0035637 91 0.016
ribonucleoside catabolic process GO:0042454 206 0.016
negative regulation of organelle organization GO:0010639 90 0.016
carbohydrate metabolic process GO:0005975 230 0.016
regulation of cell migration GO:0030334 219 0.016
protein modification by small protein conjugation GO:0032446 187 0.016
nucleoside monophosphate metabolic process GO:0009123 85 0.015
reactive oxygen species metabolic process GO:0072593 84 0.015
epithelial tube morphogenesis GO:0060562 303 0.015
cellular response to organonitrogen compound GO:0071417 145 0.015
response to oxidative stress GO:0006979 123 0.015
cellular chemical homeostasis GO:0055082 215 0.015
smoothened signaling pathway GO:0007224 105 0.015
chemotaxis GO:0006935 247 0.015
response to light stimulus GO:0009416 135 0.015
nucleoside metabolic process GO:0009116 246 0.015
cellular response to lipid GO:0071396 145 0.015
cellular response to hormone stimulus GO:0032870 150 0.015
response to inorganic substance GO:0010035 96 0.015
regulation of hydrolase activity GO:0051336 246 0.015
cognition GO:0050890 149 0.015
immune effector process GO:0002252 321 0.015
b cell differentiation GO:0030183 78 0.015
regulation of membrane potential GO:0042391 192 0.015
membrane organization GO:0061024 245 0.015
organic anion transport GO:0015711 137 0.015
oocyte axis specification GO:0007309 2 0.014
purine nucleoside catabolic process GO:0006152 205 0.014
glycoprotein metabolic process GO:0009100 116 0.014
multicellular organism growth GO:0035264 161 0.014
digestive tract development GO:0048565 190 0.014
fat cell differentiation GO:0045444 160 0.014
leukocyte activation involved in immune response GO:0002366 126 0.014
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.014
response to oxygen levels GO:0070482 62 0.014
negative regulation of cell development GO:0010721 169 0.014
cell type specific apoptotic process GO:0097285 268 0.014
development of primary sexual characteristics GO:0045137 143 0.014
wound healing GO:0042060 157 0.014
protein alkylation GO:0008213 81 0.014
ribonucleotide catabolic process GO:0009261 208 0.014
spermatid differentiation GO:0048515 115 0.014
forebrain development GO:0030900 302 0.014
purine nucleoside monophosphate metabolic process GO:0009126 81 0.014
nuclear transport GO:0051169 139 0.014
morphogenesis of a branching structure GO:0001763 203 0.014
posttranscriptional regulation of gene expression GO:0010608 155 0.014
response to peptide hormone GO:0043434 127 0.014
nucleocytoplasmic transport GO:0006913 139 0.014
cation transport GO:0006812 399 0.014
organonitrogen compound biosynthetic process GO:1901566 192 0.014
action potential GO:0001508 78 0.014
negative regulation of molecular function GO:0044092 258 0.014
stem cell maintenance GO:0019827 130 0.014
t cell activation GO:0042110 289 0.014
ribonucleoside monophosphate metabolic process GO:0009161 80 0.013
morphogenesis of embryonic epithelium GO:0016331 159 0.013
regulation of cell motility GO:2000145 236 0.013
regulation of cellular response to stress GO:0080135 159 0.013
establishment of protein localization to organelle GO:0072594 118 0.013
stem cell proliferation GO:0072089 117 0.013
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.013
gland development GO:0048732 330 0.013
tube formation GO:0035148 140 0.013
response to organic cyclic compound GO:0014070 198 0.013
purine nucleoside metabolic process GO:0042278 241 0.013
inorganic ion transmembrane transport GO:0098660 234 0.013
protein methylation GO:0006479 81 0.013
developmental maturation GO:0021700 193 0.013
endocytosis GO:0006897 168 0.013
ameboidal type cell migration GO:0001667 128 0.013
peptidyl lysine modification GO:0018205 77 0.013
regulation of binding GO:0051098 111 0.013
ras protein signal transduction GO:0007265 77 0.013
skeletal muscle organ development GO:0060538 163 0.013
protein targeting GO:0006605 143 0.013
dephosphorylation GO:0016311 129 0.013
mitochondrion organization GO:0007005 134 0.013
appendage development GO:0048736 166 0.013
cartilage development GO:0051216 140 0.013
inorganic cation transmembrane transport GO:0098662 207 0.013
tissue homeostasis GO:0001894 115 0.012
morphogenesis of a branching epithelium GO:0061138 193 0.012
negative regulation of cell fate specification GO:0009996 4 0.012
organic hydroxy compound metabolic process GO:1901615 203 0.012
protein processing GO:0016485 163 0.012
establishment or maintenance of cell polarity GO:0007163 86 0.012
regulation of neuron apoptotic process GO:0043523 122 0.012
regulation of adaptive immune response GO:0002819 90 0.012
cellular response to biotic stimulus GO:0071216 92 0.012
negative regulation of protein modification process GO:0031400 163 0.012
epidermis development GO:0008544 187 0.012
heart process GO:0003015 94 0.012
rhythmic process GO:0048511 174 0.012
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.012
connective tissue development GO:0061448 179 0.012
regulation of transferase activity GO:0051338 263 0.012
atp metabolic process GO:0046034 75 0.012
leukocyte mediated immunity GO:0002443 174 0.012
nuclear import GO:0051170 95 0.012
positive regulation of kinase activity GO:0033674 155 0.012
homeostasis of number of cells GO:0048872 210 0.012
interleukin 8 production GO:0032637 4 0.012
regulation of lymphocyte activation GO:0051249 240 0.012
carbohydrate derivative biosynthetic process GO:1901137 183 0.012
eye photoreceptor cell differentiation GO:0001754 41 0.012
histone lysine methylation GO:0034968 50 0.012
regulation of wnt signaling pathway GO:0030111 123 0.012
gliogenesis GO:0042063 141 0.012
lymphocyte activation involved in immune response GO:0002285 93 0.012
regulation of multi organism process GO:0043900 111 0.011
lateral inhibition GO:0046331 1 0.011
muscle system process GO:0003012 141 0.011
protein ubiquitination GO:0016567 171 0.011
regulation of cytoplasmic transport GO:1903649 112 0.011
regulation of meiotic cell cycle GO:0051445 34 0.011
female gamete generation GO:0007292 74 0.011
appendage morphogenesis GO:0035107 149 0.011
multicellular organismal homeostasis GO:0048871 164 0.011
t cell differentiation GO:0030217 174 0.011
meiotic cell cycle process GO:1903046 77 0.011
regulation of cysteine type endopeptidase activity GO:2000116 65 0.011
positive regulation of growth GO:0045927 104 0.011
negative regulation of apoptotic signaling pathway GO:2001234 104 0.011
protein localization to nucleus GO:0034504 121 0.011
response to peptide GO:1901652 136 0.011
kidney development GO:0001822 213 0.011
transmission of nerve impulse GO:0019226 76 0.011
anion transport GO:0006820 177 0.011
cell maturation GO:0048469 127 0.011
regulation of protein kinase activity GO:0045859 232 0.011
regulation of leukocyte differentiation GO:1902105 159 0.011
protein polymerization GO:0051258 57 0.011
negative regulation of intracellular signal transduction GO:1902532 167 0.011
regulation of mitotic cell cycle GO:0007346 126 0.011
histone methylation GO:0016571 71 0.011
regulation of cellular component biogenesis GO:0044087 181 0.011
renal system development GO:0072001 225 0.011
adaptive immune response GO:0002250 155 0.011
negative regulation of neuron apoptotic process GO:0043524 92 0.011
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.011
digestive system development GO:0055123 200 0.011
male meiosis GO:0007140 37 0.011
protein import into nucleus GO:0006606 95 0.011
positive regulation of protein kinase activity GO:0045860 144 0.011
regulation of protein localization GO:0032880 231 0.011
cilium assembly GO:0042384 81 0.011
reactive oxygen species biosynthetic process GO:1903409 8 0.011
response to acid chemical GO:0001101 111 0.011
positive regulation of cell activation GO:0050867 158 0.011
b cell activation involved in immune response GO:0002312 50 0.011
divalent metal ion transport GO:0070838 172 0.011
regulation of cellular catabolic process GO:0031329 242 0.011
cell division GO:0051301 120 0.011
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.011
cell cycle switching mitotic to meiotic cell cycle GO:0051728 1 0.011
sensory perception GO:0007600 245 0.011
regulation of homeostatic process GO:0032844 182 0.011
response to insulin GO:0032868 100 0.011
regulation of mitotic cell cycle phase transition GO:1901990 73 0.011
purine nucleoside monophosphate catabolic process GO:0009128 58 0.010
positive regulation of hydrolase activity GO:0051345 148 0.010
cell recognition GO:0008037 83 0.010
defense response to bacterium GO:0042742 119 0.010
endomembrane system organization GO:0010256 147 0.010
carboxylic acid transport GO:0046942 100 0.010
positive regulation of nervous system development GO:0051962 221 0.010
glycoprotein biosynthetic process GO:0009101 89 0.010
regulation of reactive oxygen species metabolic process GO:2000377 40 0.010
cellular response to nutrient levels GO:0031669 64 0.010
antimicrobial peptide biosynthetic process GO:0002777 2 0.010
negative regulation of phosphate metabolic process GO:0045936 184 0.010
cell substrate adhesion GO:0031589 130 0.010
regulation of secretion GO:0051046 274 0.010
regulation of protein complex assembly GO:0043254 83 0.010
carboxylic acid biosynthetic process GO:0046394 86 0.010
organic acid biosynthetic process GO:0016053 86 0.010
prevention of polyspermy GO:0060468 4 0.010
branching morphogenesis of an epithelial tube GO:0048754 159 0.010
epithelial tube formation GO:0072175 130 0.010
regulation of intrinsic apoptotic signaling pathway GO:2001242 61 0.010
reactive nitrogen species metabolic process GO:2001057 0 0.010
positive regulation of cellular component biogenesis GO:0044089 94 0.010
translation GO:0006412 93 0.010
peptidyl serine modification GO:0018209 83 0.010

Mtr disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.029
nervous system disease DOID:863 0 0.029
immune system disease DOID:2914 0 0.023
disease of metabolism DOID:0014667 0 0.018
musculoskeletal system disease DOID:17 0 0.017
sensory system disease DOID:0050155 0 0.015
eye and adnexa disease DOID:1492 0 0.015
disease of cellular proliferation DOID:14566 0 0.014
cancer DOID:162 0 0.014
hematopoietic system disease DOID:74 0 0.014
inherited metabolic disorder DOID:655 0 0.014
eye disease DOID:5614 0 0.014
central nervous system disease DOID:331 0 0.013
organ system cancer DOID:0050686 0 0.012
connective tissue disease DOID:65 0 0.011