Mus musculus

64 known processes

Trpm8

transient receptor potential cation channel, subfamily M, member 8

(Aliases: TRPP8,CMR1,MGC2849,Trp-p8,LTRPC6,LTrpC-6)

Trpm8 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of membrane potential GO:0042391 192 0.135
regulation of cellular ketone metabolic process GO:0010565 66 0.080
muscle system process GO:0003012 141 0.067
macromolecule catabolic process GO:0009057 281 0.063
negative regulation of cellular component organization GO:0051129 194 0.063
monocarboxylic acid metabolic process GO:0032787 191 0.060
amine metabolic process GO:0009308 45 0.056
axonogenesis GO:0007409 274 0.055
carbohydrate metabolic process GO:0005975 230 0.048
regulation of anatomical structure size GO:0090066 178 0.045
regionalization GO:0003002 337 0.044
membrane organization GO:0061024 245 0.042
regulation of system process GO:0044057 200 0.041
inorganic ion transmembrane transport GO:0098660 234 0.040
cellular amino acid metabolic process GO:0006520 103 0.039
peptidyl serine modification GO:0018209 83 0.039
protein maturation GO:0051604 176 0.039
negative regulation of cell development GO:0010721 169 0.036
regulation of epithelial cell proliferation GO:0050678 141 0.036
urogenital system development GO:0001655 261 0.036
cellular amine metabolic process GO:0044106 44 0.036
regulation of cellular amino acid metabolic process GO:0006521 5 0.034
circulatory system process GO:0003013 197 0.033
regulation of secretion GO:0051046 274 0.032
cellular lipid metabolic process GO:0044255 323 0.032
skin development GO:0043588 220 0.032
response to peptide GO:1901652 136 0.032
muscle contraction GO:0006936 101 0.030
sensory organ morphogenesis GO:0090596 242 0.030
Mouse
blood circulation GO:0008015 195 0.030
cellular response to insulin stimulus GO:0032869 78 0.029
regulation of kinase activity GO:0043549 249 0.028
gland development GO:0048732 330 0.028
protein processing GO:0016485 163 0.028
regulation of cellular amine metabolic process GO:0033238 20 0.027
cellular response to hormone stimulus GO:0032870 150 0.027
multicellular organism growth GO:0035264 161 0.027
mapk cascade GO:0000165 281 0.027
regulation of cell projection organization GO:0031344 206 0.027
action potential GO:0001508 78 0.027
peptidyl amino acid modification GO:0018193 336 0.026
regulation of neuron differentiation GO:0045664 281 0.026
regulation of neuron projection development GO:0010975 169 0.026
positive regulation of cell development GO:0010720 237 0.026
chemotaxis GO:0006935 247 0.026
Mouse
cell fate commitment GO:0045165 210 0.025
regulation of cellular component size GO:0032535 121 0.025
hematopoietic progenitor cell differentiation GO:0002244 143 0.024
learning or memory GO:0007611 148 0.024
small gtpase mediated signal transduction GO:0007264 97 0.024
transmission of nerve impulse GO:0019226 76 0.024
transmembrane transport GO:0055085 412 0.024
digestive system development GO:0055123 200 0.024
male gamete generation GO:0048232 285 0.024
inflammatory response GO:0006954 244 0.024
response to organonitrogen compound GO:0010243 246 0.024
telencephalon development GO:0021537 186 0.023
cognition GO:0050890 149 0.023
kidney development GO:0001822 213 0.023
fertilization GO:0009566 127 0.023
multicellular organismal signaling GO:0035637 91 0.023
cellular response to organonitrogen compound GO:0071417 145 0.023
oxidation reduction process GO:0055114 342 0.022
extracellular matrix organization GO:0030198 147 0.022
cellular ketone metabolic process GO:0042180 84 0.022
asymmetric stem cell division GO:0098722 3 0.022
carbohydrate derivative catabolic process GO:1901136 231 0.022
multi multicellular organism process GO:0044706 109 0.022
extracellular structure organization GO:0043062 148 0.022
aromatic compound catabolic process GO:0019439 286 0.022
response to peptide hormone GO:0043434 127 0.021
negative regulation of nervous system development GO:0051961 156 0.021
regulation of cellular response to stress GO:0080135 159 0.021
steroid metabolic process GO:0008202 119 0.021
microtubule based process GO:0007017 236 0.021
nitrogen compound transport GO:0071705 271 0.021
organonitrogen compound catabolic process GO:1901565 264 0.021
central nervous system neuron differentiation GO:0021953 162 0.021
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.021
nucleobase containing small molecule metabolic process GO:0055086 352 0.021
synapse organization GO:0050808 125 0.021
cell growth involved in cardiac muscle cell development GO:0061049 3 0.021
ossification GO:0001503 216 0.021
pallium development GO:0021543 120 0.020
physiological cardiac muscle hypertrophy GO:0003301 3 0.020
endomembrane system organization GO:0010256 147 0.020
regulation of response to wounding GO:1903034 189 0.020
forebrain development GO:0030900 302 0.020
response to radiation GO:0009314 165 0.020
Mouse
dna metabolic process GO:0006259 303 0.020
spermatogenesis GO:0007283 284 0.020
positive regulation of vasoconstriction GO:0045907 4 0.020
sensory perception GO:0007600 245 0.020
actin filament organization GO:0007015 113 0.019
regulation of cell cycle GO:0051726 281 0.019
heterocycle catabolic process GO:0046700 280 0.019
positive regulation of cellular amine metabolic process GO:0033240 5 0.019
regulation of transferase activity GO:0051338 263 0.019
cation transport GO:0006812 399 0.019
morphogenesis of embryonic epithelium GO:0016331 159 0.019
response to nutrient levels GO:0031667 109 0.019
positive regulation of kinase activity GO:0033674 155 0.019
cell adhesion GO:0007155 329 0.019
Mouse
regulation of organelle organization GO:0033043 289 0.019
cellular ion homeostasis GO:0006873 165 0.018
leukocyte differentiation GO:0002521 342 0.018
organic cyclic compound catabolic process GO:1901361 295 0.018
cellular response to peptide GO:1901653 92 0.018
regulation of cellular component biogenesis GO:0044087 181 0.018
negative regulation of cell cycle GO:0045786 123 0.018
cation transmembrane transport GO:0098655 266 0.018
regulation of binding GO:0051098 111 0.018
regulation of blood circulation GO:1903522 93 0.017
single fertilization GO:0007338 82 0.017
germ cell development GO:0007281 185 0.017
response to fibroblast growth factor GO:0071774 47 0.017
metal ion homeostasis GO:0055065 189 0.017
respiratory tube development GO:0030323 167 0.017
regulation of ossification GO:0030278 112 0.017
synaptic transmission GO:0007268 329 0.017
apoptotic signaling pathway GO:0097190 306 0.017
epidermis development GO:0008544 187 0.017
response to testosterone GO:0033574 3 0.017
regulation of transporter activity GO:0032409 57 0.017
negative regulation of neuron projection regeneration GO:0070571 3 0.017
positive regulation of cell death GO:0010942 224 0.017
nuclear division GO:0000280 158 0.017
rhythmic process GO:0048511 174 0.017
purine nucleotide metabolic process GO:0006163 302 0.016
regulation of ion transport GO:0043269 215 0.016
purine containing compound metabolic process GO:0072521 311 0.016
photoreceptor cell development GO:0042461 40 0.016
Mouse
cellular response to peptide hormone stimulus GO:0071375 92 0.016
homeostasis of number of cells GO:0048872 210 0.016
organic acid catabolic process GO:0016054 51 0.016
response to extracellular stimulus GO:0009991 127 0.016
negative regulation of cellular amine metabolic process GO:0033239 1 0.016
wnt signaling pathway GO:0016055 188 0.016
reactive oxygen species metabolic process GO:0072593 84 0.016
protein ubiquitination GO:0016567 171 0.016
developmental maturation GO:0021700 193 0.016
regulation of mapk cascade GO:0043408 248 0.016
insulin receptor signaling pathway GO:0008286 49 0.016
ribonucleotide metabolic process GO:0009259 291 0.016
reactive nitrogen species metabolic process GO:2001057 0 0.016
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.016
mesodermal cell migration GO:0008078 4 0.015
glycosylation GO:0070085 62 0.015
purine nucleoside metabolic process GO:0042278 241 0.015
cellular response to lipid GO:0071396 145 0.015
small molecule biosynthetic process GO:0044283 132 0.015
neuronal action potential GO:0019228 54 0.015
inorganic cation transmembrane transport GO:0098662 207 0.015
nucleotide metabolic process GO:0009117 332 0.015
regulation of action potential GO:0098900 4 0.015
endothelial cell differentiation GO:0045446 41 0.015
negative regulation of phosphorylation GO:0042326 166 0.015
posttranscriptional regulation of gene expression GO:0010608 155 0.015
protein localization to organelle GO:0033365 185 0.015
negative regulation of cell growth involved in cardiac muscle cell development GO:0061052 2 0.015
regulation of angiotensin levels in blood GO:0002002 4 0.015
cell type specific apoptotic process GO:0097285 268 0.015
organelle fission GO:0048285 170 0.015
negative regulation of protein metabolic process GO:0051248 282 0.015
response to insulin GO:0032868 100 0.015
regulation of ion transmembrane transport GO:0034765 119 0.015
g protein coupled receptor signaling pathway GO:0007186 243 0.015
sulfur compound metabolic process GO:0006790 100 0.015
positive regulation of secretion by cell GO:1903532 114 0.015
protein modification by small protein conjugation or removal GO:0070647 207 0.014
somitogenesis GO:0001756 69 0.014
renal system development GO:0072001 225 0.014
protein localization to membrane GO:0072657 108 0.014
cellular nitrogen compound catabolic process GO:0044270 280 0.014
lipid biosynthetic process GO:0008610 179 0.014
ribose phosphate metabolic process GO:0019693 291 0.014
phospholipid metabolic process GO:0006644 87 0.014
cellular response to external stimulus GO:0071496 88 0.014
divalent inorganic cation homeostasis GO:0072507 138 0.014
learning GO:0007612 98 0.014
regulation of lymphocyte mediated immunity GO:0002706 84 0.014
regulation of feeding behavior GO:0060259 3 0.014
organonitrogen compound biosynthetic process GO:1901566 192 0.014
heart process GO:0003015 94 0.014
macromolecule glycosylation GO:0043413 55 0.014
epithelial cell proliferation GO:0050673 174 0.014
small molecule catabolic process GO:0044282 71 0.014
positive regulation of secretion GO:0051047 130 0.014
response to lipopolysaccharide GO:0032496 128 0.014
development of primary male sexual characteristics GO:0046546 88 0.014
carbohydrate derivative biosynthetic process GO:1901137 183 0.014
neuron projection guidance GO:0097485 141 0.014
physiological muscle hypertrophy GO:0003298 3 0.014
positive regulation of growth GO:0045927 104 0.014
cellular response to extracellular stimulus GO:0031668 81 0.014
positive regulation of protein modification process GO:0031401 299 0.014
monosaccharide metabolic process GO:0005996 106 0.014
cytokine production GO:0001816 319 0.014
purine ribonucleoside metabolic process GO:0046128 241 0.014
response to acid chemical GO:0001101 111 0.014
respiratory system development GO:0060541 190 0.014
nucleotide catabolic process GO:0009166 217 0.014
mesonephric epithelium development GO:0072163 94 0.014
regulation of secretion by cell GO:1903530 249 0.014
cell maturation GO:0048469 127 0.013
glycoprotein metabolic process GO:0009100 116 0.013
negative regulation of phosphate metabolic process GO:0045936 184 0.013
tube formation GO:0035148 140 0.013
protein glycosylation GO:0006486 55 0.013
vasodilation GO:0042311 28 0.013
cellular metal ion homeostasis GO:0006875 151 0.013
embryonic placenta development GO:0001892 98 0.013
regulation of vesicle mediated transport GO:0060627 139 0.013
negative regulation of cellular protein metabolic process GO:0032269 247 0.013
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.013
negative regulation of neuron projection development GO:0010977 50 0.013
epithelial tube morphogenesis GO:0060562 303 0.013
positive regulation of organelle organization GO:0010638 128 0.013
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.013
positive regulation of nervous system development GO:0051962 221 0.013
glycoprotein biosynthetic process GO:0009101 89 0.013
nucleoside triphosphate metabolic process GO:0009141 230 0.013
oocyte construction GO:0007308 2 0.012
protein oligomerization GO:0051259 67 0.012
nucleocytoplasmic transport GO:0006913 139 0.012
regulation of cell growth GO:0001558 91 0.012
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.012
purine ribonucleotide metabolic process GO:0009150 290 0.012
nucleoside phosphate metabolic process GO:0006753 338 0.012
nucleoside metabolic process GO:0009116 246 0.012
cellular homeostasis GO:0019725 240 0.012
stem cell maintenance GO:0019827 130 0.012
positive regulation of ion transport GO:0043270 65 0.012
regulation of hormone levels GO:0010817 211 0.012
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.012
ribonucleotide catabolic process GO:0009261 208 0.012
regulation of cell growth involved in cardiac muscle cell development GO:0061050 3 0.012
positive regulation of transferase activity GO:0051347 167 0.012
regulation of cell cycle process GO:0010564 160 0.012
stem cell proliferation GO:0072089 117 0.012
glycosyl compound metabolic process GO:1901657 246 0.012
cellular macromolecule catabolic process GO:0044265 206 0.012
ear development GO:0043583 200 0.012
organic hydroxy compound metabolic process GO:1901615 203 0.012
limb morphogenesis GO:0035108 149 0.012
neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 18 0.012
negative regulation of organelle organization GO:0010639 90 0.012
positive regulation of apoptotic process GO:0043065 217 0.012
negative regulation of molecular function GO:0044092 258 0.012
meiotic nuclear division GO:0007126 115 0.012
protein catabolic process GO:0030163 221 0.012
glycerolipid metabolic process GO:0046486 122 0.012
interleukin 8 production GO:0032637 4 0.012
regulation of protein kinase activity GO:0045859 232 0.012
regulation of protein processing GO:0070613 96 0.012
circadian rhythm GO:0007623 114 0.011
amide transport GO:0042886 138 0.011
mitotic cell cycle GO:0000278 195 0.011
response to monosaccharide GO:0034284 67 0.011
cytoplasmic transport GO:0016482 234 0.011
appendage morphogenesis GO:0035107 149 0.011
zymogen activation GO:0031638 41 0.011
anatomical structure homeostasis GO:0060249 145 0.011
regulation of systemic arterial blood pressure GO:0003073 61 0.011
purine nucleoside triphosphate metabolic process GO:0009144 226 0.011
negative regulation of protein modification process GO:0031400 163 0.011
response to molecule of bacterial origin GO:0002237 143 0.011
protein modification by small protein conjugation GO:0032446 187 0.011
retina development in camera type eye GO:0060041 119 0.011
organelle assembly GO:0070925 177 0.011
regulation of body fluid levels GO:0050878 162 0.011
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.011
response to inorganic substance GO:0010035 96 0.011
dna recombination GO:0006310 92 0.011
positive regulation of protein phosphorylation GO:0001934 242 0.011
t cell differentiation GO:0030217 174 0.011
potassium ion transmembrane transport GO:0071805 43 0.011
Mouse
memory GO:0007613 58 0.011
regulation of protein localization GO:0032880 231 0.011
positive regulation of binding GO:0051099 49 0.011
axon guidance GO:0007411 141 0.011
ion transmembrane transport GO:0034220 361 0.011
cilium assembly GO:0042384 81 0.011
organophosphate catabolic process GO:0046434 232 0.011
sensory perception of sound GO:0007605 97 0.011
negative regulation of response to wounding GO:1903035 77 0.011
epithelial cell development GO:0002064 159 0.011
regulation of neurotransmitter levels GO:0001505 87 0.011
ribonucleoside metabolic process GO:0009119 245 0.011
detection of stimulus GO:0051606 84 0.011
leukocyte mediated immunity GO:0002443 174 0.011
regulation of cytokine production GO:0001817 266 0.011
oocyte axis specification GO:0007309 2 0.011
glucose homeostasis GO:0042593 128 0.011
sperm egg recognition GO:0035036 37 0.010
male sex differentiation GO:0046661 109 0.010
heart morphogenesis GO:0003007 178 0.010
regulation of lipid metabolic process GO:0019216 118 0.010
protein targeting GO:0006605 143 0.010
cellular protein complex assembly GO:0043623 116 0.010
binding of sperm to zona pellucida GO:0007339 34 0.010
kidney mesenchyme morphogenesis GO:0072131 4 0.010
regulation of metal ion transport GO:0010959 106 0.010
carboxylic acid biosynthetic process GO:0046394 86 0.010
negative regulation of phosphorus metabolic process GO:0010563 184 0.010
single organism cell adhesion GO:0098602 156 0.010
regulation of blood pressure GO:0008217 93 0.010
negative regulation of cytokine production GO:0001818 84 0.010
potassium ion transport GO:0006813 52 0.010
Mouse
regulation of cell size GO:0008361 72 0.010
organic acid biosynthetic process GO:0016053 86 0.010
carbohydrate biosynthetic process GO:0016051 74 0.010
negative regulation of multi organism process GO:0043901 68 0.010

Trpm8 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
nervous system disease DOID:863 0 0.016
disease of anatomical entity DOID:7 0 0.016
disease of metabolism DOID:0014667 0 0.014
disease of cellular proliferation DOID:14566 0 0.011
musculoskeletal system disease DOID:17 0 0.010