Mus musculus

15 known processes

Trpm6

transient receptor potential cation channel, subfamily M, member 6

(Aliases: CHAK2,TRPM6/CHAK2)

Trpm6 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
ion transmembrane transport GO:0034220 361 0.389
urogenital system development GO:0001655 261 0.190
steroid metabolic process GO:0008202 119 0.141
stem cell development GO:0048864 219 0.130
transmembrane transport GO:0055085 412 0.126
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.124
respiratory system development GO:0060541 190 0.121
regionalization GO:0003002 337 0.113
regulation of cellular amine metabolic process GO:0033238 20 0.111
dna metabolic process GO:0006259 303 0.104
organic hydroxy compound metabolic process GO:1901615 203 0.100
regulation of cell motility GO:2000145 236 0.088
cation transport GO:0006812 399 0.084
positive regulation of cell development GO:0010720 237 0.084
purine nucleotide metabolic process GO:0006163 302 0.083
regulation of cell cycle GO:0051726 281 0.083
regulation of cellular catabolic process GO:0031329 242 0.081
negative regulation of cellular protein metabolic process GO:0032269 247 0.081
protein processing GO:0016485 163 0.080
muscle cell differentiation GO:0042692 261 0.076
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.075
macromolecule catabolic process GO:0009057 281 0.075
cation transmembrane transport GO:0098655 266 0.071
cellular ketone metabolic process GO:0042180 84 0.070
cellular amine metabolic process GO:0044106 44 0.070
stem cell differentiation GO:0048863 268 0.069
amine metabolic process GO:0009308 45 0.069
positive regulation of apoptotic process GO:0043065 217 0.067
cell adhesion GO:0007155 329 0.066
Mouse
response to organonitrogen compound GO:0010243 246 0.065
kidney development GO:0001822 213 0.065
chemotaxis GO:0006935 247 0.062
Mouse
mitotic cell cycle GO:0000278 195 0.061
Worm
regulation of cellular amino acid metabolic process GO:0006521 5 0.060
renal system development GO:0072001 225 0.059
organic cyclic compound catabolic process GO:1901361 295 0.059
positive regulation of cellular amine metabolic process GO:0033240 5 0.059
male gamete generation GO:0048232 285 0.058
nucleobase containing small molecule metabolic process GO:0055086 352 0.056
response to transforming growth factor beta GO:0071559 88 0.056
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.056
gland development GO:0048732 330 0.054
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.053
inorganic cation transmembrane transport GO:0098662 207 0.053
Mouse
cellular amino acid metabolic process GO:0006520 103 0.053
regulation of hydrolase activity GO:0051336 246 0.053
regulation of ion transport GO:0043269 215 0.052
aromatic compound catabolic process GO:0019439 286 0.052
gonad development GO:0008406 141 0.052
Worm
homeostasis of number of cells GO:0048872 210 0.052
locomotory behavior GO:0007626 195 0.051
organonitrogen compound catabolic process GO:1901565 264 0.051
protein maturation GO:0051604 176 0.051
spermatogenesis GO:0007283 284 0.050
ribose phosphate metabolic process GO:0019693 291 0.049
neuron projection guidance GO:0097485 141 0.049
lung development GO:0030324 164 0.049
regulation of cell migration GO:0030334 219 0.049
embryonic organ morphogenesis GO:0048562 276 0.049
myeloid cell differentiation GO:0030099 233 0.049
ribonucleoside metabolic process GO:0009119 245 0.047
protein catabolic process GO:0030163 221 0.047
positive regulation of protein modification process GO:0031401 299 0.047
membrane organization GO:0061024 245 0.047
glycosyl compound metabolic process GO:1901657 246 0.046
glycosyl compound catabolic process GO:1901658 206 0.046
negative regulation of cell proliferation GO:0008285 296 0.046
cellular nitrogen compound catabolic process GO:0044270 280 0.045
positive regulation of programmed cell death GO:0043068 218 0.044
nucleotide metabolic process GO:0009117 332 0.044
nucleoside phosphate metabolic process GO:0006753 338 0.044
purine containing compound metabolic process GO:0072521 311 0.043
purine ribonucleoside metabolic process GO:0046128 241 0.043
nucleoside metabolic process GO:0009116 246 0.043
hindbrain development GO:0030902 128 0.042
regulation of mitotic cell cycle GO:0007346 126 0.042
negative regulation of molecular function GO:0044092 258 0.042
negative regulation of protein metabolic process GO:0051248 282 0.042
blood vessel morphogenesis GO:0048514 285 0.042
ossification GO:0001503 216 0.042
regulation of cell cycle process GO:0010564 160 0.041
negative regulation of immune system process GO:0002683 209 0.041
negative regulation of growth GO:0045926 99 0.041
regulation of lipid metabolic process GO:0019216 118 0.041
inorganic ion transmembrane transport GO:0098660 234 0.040
Mouse
alcohol metabolic process GO:0006066 116 0.040
heterocycle catabolic process GO:0046700 280 0.040
negative regulation of phosphorylation GO:0042326 166 0.040
nucleoside phosphate catabolic process GO:1901292 222 0.039
camera type eye development GO:0043010 266 0.039
purine nucleotide catabolic process GO:0006195 211 0.039
carbohydrate derivative catabolic process GO:1901136 231 0.039
connective tissue development GO:0061448 179 0.039
organophosphate catabolic process GO:0046434 232 0.038
negative regulation of cell cycle GO:0045786 123 0.038
multicellular organismal signaling GO:0035637 91 0.038
positive regulation of neuron differentiation GO:0045666 141 0.038
cellular response to growth factor stimulus GO:0071363 197 0.038
purine ribonucleoside catabolic process GO:0046130 205 0.037
cellular response to oxidative stress GO:0034599 76 0.037
morphogenesis of embryonic epithelium GO:0016331 159 0.037
developmental growth involved in morphogenesis GO:0060560 138 0.037
purine nucleoside catabolic process GO:0006152 205 0.037
respiratory tube development GO:0030323 167 0.037
cellular lipid metabolic process GO:0044255 323 0.037
extracellular structure organization GO:0043062 148 0.036
response to extracellular stimulus GO:0009991 127 0.036
regulation of proteolysis GO:0030162 164 0.035
ribonucleoside triphosphate metabolic process GO:0009199 220 0.035
regulation of membrane potential GO:0042391 192 0.035
sensory perception GO:0007600 245 0.035
Mouse
positive regulation of cell cycle GO:0045787 92 0.035
angiogenesis GO:0001525 201 0.035
muscle tissue development GO:0060537 308 0.035
meiotic cell cycle GO:0051321 122 0.035
positive regulation of protein phosphorylation GO:0001934 242 0.035
ribonucleotide catabolic process GO:0009261 208 0.035
ribonucleotide metabolic process GO:0009259 291 0.035
inflammatory response GO:0006954 244 0.035
liver development GO:0001889 66 0.035
striated muscle tissue development GO:0014706 293 0.034
multicellular organism growth GO:0035264 161 0.034
regulation of neuron differentiation GO:0045664 281 0.034
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.034
negative regulation of cellular component organization GO:0051129 194 0.034
purine nucleoside triphosphate catabolic process GO:0009146 203 0.034
leukocyte differentiation GO:0002521 342 0.034
nucleoside catabolic process GO:0009164 206 0.034
digestive tract morphogenesis GO:0048546 147 0.033
positive regulation of cell death GO:0010942 224 0.033
action potential GO:0001508 78 0.033
regulation of cell adhesion GO:0030155 154 0.033
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.032
extracellular matrix organization GO:0030198 147 0.032
ameboidal type cell migration GO:0001667 128 0.032
positive regulation of cellular catabolic process GO:0031331 148 0.032
regulation of cellular ketone metabolic process GO:0010565 66 0.032
stem cell proliferation GO:0072089 117 0.032
purine ribonucleotide metabolic process GO:0009150 290 0.032
positive regulation of nervous system development GO:0051962 221 0.032
monocarboxylic acid metabolic process GO:0032787 191 0.032
regulation of multi organism process GO:0043900 111 0.032
forebrain development GO:0030900 302 0.031
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.031
ribonucleoside triphosphate catabolic process GO:0009203 199 0.031
cellular potassium ion transport GO:0071804 43 0.031
Mouse
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.031
regulation of cellular response to stress GO:0080135 159 0.031
anion transport GO:0006820 177 0.031
epithelial tube morphogenesis GO:0060562 303 0.031
organelle fission GO:0048285 170 0.031
Worm
development of primary sexual characteristics GO:0045137 143 0.031
Worm
response to lipopolysaccharide GO:0032496 128 0.030
negative regulation of cellular amine metabolic process GO:0033239 1 0.030
purine ribonucleotide catabolic process GO:0009154 208 0.030
ras protein signal transduction GO:0007265 77 0.030
nucleotide catabolic process GO:0009166 217 0.030
inner ear morphogenesis GO:0042472 101 0.030
positive regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090100 43 0.030
fat cell differentiation GO:0045444 160 0.030
innate immune response GO:0045087 157 0.029
muscle cell development GO:0055001 133 0.029
regulation of cellular component biogenesis GO:0044087 181 0.029
sensory organ morphogenesis GO:0090596 242 0.029
Mouse
regulation of t cell activation GO:0050863 170 0.029
regulation of protein processing GO:0070613 96 0.028
response to acid chemical GO:0001101 111 0.028
positive regulation of hydrolase activity GO:0051345 148 0.028
response to oxidative stress GO:0006979 123 0.028
Mouse
positive regulation of cell motility GO:2000147 116 0.028
single organism cell adhesion GO:0098602 156 0.028
cellular homeostasis GO:0019725 240 0.028
Mouse
cellular chemical homeostasis GO:0055082 215 0.028
Mouse
somatic stem cell maintenance GO:0035019 47 0.027
cellular response to hormone stimulus GO:0032870 150 0.027
female gamete generation GO:0007292 74 0.027
response to amino acid GO:0043200 37 0.027
mesoderm development GO:0007498 100 0.027
nucleoside triphosphate catabolic process GO:0009143 205 0.027
skeletal system development GO:0001501 356 0.027
regulation of intracellular transport GO:0032386 159 0.027
ribonucleoside catabolic process GO:0042454 206 0.027
epithelial cell development GO:0002064 159 0.027
regulation of protein serine threonine kinase activity GO:0071900 157 0.026
regulation of protein maturation GO:1903317 96 0.026
nephron development GO:0072006 109 0.026
regulation of protein transport GO:0051223 163 0.026
transforming growth factor beta receptor signaling pathway GO:0007179 71 0.026
tissue migration GO:0090130 68 0.026
germ cell development GO:0007281 185 0.026
regulation of purine nucleotide metabolic process GO:1900542 169 0.026
cellular response to transforming growth factor beta stimulus GO:0071560 88 0.026
metal ion homeostasis GO:0055065 189 0.026
Mouse Fly
heart morphogenesis GO:0003007 178 0.026
divalent inorganic cation transport GO:0072511 178 0.026
Mouse Fly
neural tube development GO:0021915 160 0.025
response to growth factor GO:0070848 198 0.025
striated muscle cell development GO:0055002 125 0.025
neural tube formation GO:0001841 108 0.025
placenta development GO:0001890 140 0.025
cell fate commitment GO:0045165 210 0.025
regulation of transferase activity GO:0051338 263 0.025
positive regulation of proteolysis GO:0045862 85 0.025
telencephalon development GO:0021537 186 0.025
regulation of organelle organization GO:0033043 289 0.024
response to drug GO:0042493 75 0.024
regulation of map kinase activity GO:0043405 120 0.024
purine nucleoside metabolic process GO:0042278 241 0.024
mesenchyme development GO:0060485 152 0.024
ureteric bud development GO:0001657 94 0.024
mapk cascade GO:0000165 281 0.024
small gtpase mediated signal transduction GO:0007264 97 0.024
immune effector process GO:0002252 321 0.024
regulation of cellular response to growth factor stimulus GO:0090287 82 0.024
t cell activation GO:0042110 289 0.024
positive regulation of defense response GO:0031349 124 0.024
kidney epithelium development GO:0072073 121 0.024
compound eye development GO:0048749 1 0.024
response to molecule of bacterial origin GO:0002237 143 0.023
negative regulation of synapse assembly GO:0051964 3 0.023
regulation of mapk cascade GO:0043408 248 0.023
modification dependent protein catabolic process GO:0019941 133 0.023
modification dependent macromolecule catabolic process GO:0043632 133 0.023
endomembrane system organization GO:0010256 147 0.023
regulation of establishment of protein localization GO:0070201 181 0.023
regulation of cell activation GO:0050865 289 0.023
purine containing compound catabolic process GO:0072523 213 0.023
regulation of leukocyte differentiation GO:1902105 159 0.023
positive regulation of synaptic growth at neuromuscular junction GO:0045887 1 0.023
digestive system development GO:0055123 200 0.022
maintenance of location GO:0051235 89 0.022
cellular macromolecule catabolic process GO:0044265 206 0.022
dna endoreduplication GO:0042023 4 0.022
neural precursor cell proliferation GO:0061351 121 0.022
tube formation GO:0035148 140 0.022
lymphocyte differentiation GO:0030098 242 0.022
adult locomotory behavior GO:0008344 91 0.022
cellular protein catabolic process GO:0044257 155 0.022
apoptotic signaling pathway GO:0097190 306 0.022
cellularization GO:0007349 1 0.022
regulation of homeostatic process GO:0032844 182 0.022
myeloid leukocyte differentiation GO:0002573 119 0.022
positive regulation of neuron projection development GO:0010976 79 0.022
negative regulation of proteolysis GO:0045861 74 0.021
bmp signaling pathway GO:0030509 93 0.021
gtp metabolic process GO:0046039 144 0.021
columnar cuboidal epithelial cell differentiation GO:0002065 82 0.021
negative regulation of phosphorus metabolic process GO:0010563 184 0.021
glial cell development GO:0021782 54 0.021
muscle system process GO:0003012 141 0.021
regulation of nucleoside metabolic process GO:0009118 130 0.021
negative regulation of protein maturation GO:1903318 79 0.021
regulation of secretion GO:0051046 274 0.021
regulation of kinase activity GO:0043549 249 0.021
regulation of protein catabolic process GO:0042176 108 0.021
regulation of neuron death GO:1901214 134 0.021
protein modification by small protein conjugation or removal GO:0070647 207 0.021
mesenchymal cell development GO:0014031 93 0.021
negative regulation of phosphate metabolic process GO:0045936 184 0.020
dephosphorylation GO:0016311 129 0.020
lipid biosynthetic process GO:0008610 179 0.020
reactive oxygen species metabolic process GO:0072593 84 0.020
canonical wnt signaling pathway GO:0060070 130 0.020
organonitrogen compound biosynthetic process GO:1901566 192 0.020
regulation of metal ion transport GO:0010959 106 0.020
negative regulation of cell cycle process GO:0010948 69 0.020
actin cytoskeleton organization GO:0030036 220 0.020
Mouse
smoothened signaling pathway GO:0007224 105 0.020
regulation of endopeptidase activity GO:0052548 89 0.020
response to nutrient levels GO:0031667 109 0.020
purine nucleoside triphosphate metabolic process GO:0009144 226 0.020
cardiac chamber morphogenesis GO:0003206 93 0.020
epithelium migration GO:0090132 63 0.020
hepaticobiliary system development GO:0061008 67 0.020
blastocyst development GO:0001824 80 0.019
cellular response to external stimulus GO:0071496 88 0.019
g protein coupled receptor signaling pathway GO:0007186 243 0.019
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.019
peptidyl serine modification GO:0018209 83 0.019
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.019
engulfment of apoptotic cell GO:0043652 3 0.019
rho protein signal transduction GO:0007266 32 0.019
cellular ion homeostasis GO:0006873 165 0.019
Mouse
morphogenesis of a branching epithelium GO:0061138 193 0.019
adult behavior GO:0030534 135 0.019
peptidyl amino acid modification GO:0018193 336 0.019
transmission of nerve impulse GO:0019226 76 0.019
cytoplasmic transport GO:0016482 234 0.019
single organismal cell cell adhesion GO:0016337 131 0.019
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.019
nucleoside triphosphate metabolic process GO:0009141 230 0.019
wound healing GO:0042060 157 0.019
cell maturation GO:0048469 127 0.019
microtubule cytoskeleton organization GO:0000226 157 0.019
regulation of nucleotide metabolic process GO:0006140 169 0.019
regulation of protein kinase activity GO:0045859 232 0.019
regulation of reproductive process GO:2000241 66 0.018
regulation of cytoskeleton organization GO:0051493 122 0.018
intracellular mrna localization GO:0008298 4 0.018
gliogenesis GO:0042063 141 0.018
potassium ion transport GO:0006813 52 0.018
Mouse
axonogenesis GO:0007409 274 0.018
leukocyte migration GO:0050900 124 0.018
Mouse
lateral inhibition GO:0046331 1 0.018
cytokine production GO:0001816 319 0.018
notch signaling pathway GO:0007219 71 0.018
negative regulation of peptidase activity GO:0010466 46 0.018
mesenchymal cell differentiation GO:0048762 107 0.018
regulation of myeloid cell differentiation GO:0045637 96 0.018
regulation of apoptotic signaling pathway GO:2001233 197 0.018
cellular response to organonitrogen compound GO:0071417 145 0.018
interspecies interaction between organisms GO:0044419 83 0.018
positive regulation of innate immune response GO:0045089 80 0.018
skin development GO:0043588 220 0.017
negative regulation of protein modification process GO:0031400 163 0.017
intracellular protein transport GO:0006886 204 0.017
posttranscriptional regulation of gene expression GO:0010608 155 0.017
guanosine containing compound catabolic process GO:1901069 144 0.017
negative regulation of osteoblast proliferation GO:0033689 4 0.017
pallium development GO:0021543 120 0.017
cell substrate adhesion GO:0031589 130 0.017
Mouse
regulation of body fluid levels GO:0050878 162 0.017
glycoprotein metabolic process GO:0009100 116 0.017
axon guidance GO:0007411 141 0.017
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.017
positive regulation of cell migration GO:0030335 109 0.017
response to organic cyclic compound GO:0014070 198 0.017
organelle assembly GO:0070925 177 0.017
phagocytosis GO:0006909 66 0.017
cell growth GO:0016049 130 0.017
Fly
regulation of inflammatory response GO:0050727 147 0.017
synaptic transmission GO:0007268 329 0.017
protein modification by small protein conjugation GO:0032446 187 0.017
cellular response to lipid GO:0071396 145 0.017
exocrine system development GO:0035272 45 0.017
mammary gland epithelium development GO:0061180 65 0.016
regulation of organ morphogenesis GO:2000027 144 0.016
regulation of hormone levels GO:0010817 211 0.016
nuclear division GO:0000280 158 0.016
Worm
inorganic anion transmembrane transport GO:0098661 29 0.016
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 62 0.016
mesodermal cell migration GO:0008078 4 0.016
epithelial tube formation GO:0072175 130 0.016
ubiquitin dependent protein catabolic process GO:0006511 129 0.016
positive regulation of transferase activity GO:0051347 167 0.016
negative regulation of reproductive process GO:2000242 31 0.016
organelle localization GO:0051640 179 0.016
fertilization GO:0009566 127 0.016
carbohydrate metabolic process GO:0005975 230 0.016
development of primary male sexual characteristics GO:0046546 88 0.016
branching morphogenesis of an epithelial tube GO:0048754 159 0.016
oligopeptide transmembrane transport GO:0035672 4 0.016
positive regulation of protein transport GO:0051222 93 0.016
wnt signaling pathway GO:0016055 188 0.016
regulation of lymphocyte activation GO:0051249 240 0.016
metanephros development GO:0001656 79 0.016
mitotic cell cycle process GO:1903047 159 0.015
Worm
regulation of purine nucleotide catabolic process GO:0033121 122 0.015
negative regulation of intracellular signal transduction GO:1902532 167 0.015
tissue remodeling GO:0048771 102 0.015
regulation of cell division GO:0051302 76 0.015
regulation of organ growth GO:0046620 61 0.015
trabecula morphogenesis GO:0061383 40 0.015
negative regulation of protein processing GO:0010955 79 0.015
intrinsic apoptotic signaling pathway GO:0097193 132 0.015
digestive tract development GO:0048565 190 0.015
regulation of cytokine production GO:0001817 266 0.015
myotube differentiation GO:0014902 105 0.015
regulation of epithelial cell migration GO:0010632 35 0.015
regulation of ion transmembrane transport GO:0034765 119 0.015
regulation of neuron projection development GO:0010975 169 0.015
cellular response to biotic stimulus GO:0071216 92 0.015
cellular response to lipopolysaccharide GO:0071222 77 0.015
regulation of embryonic development GO:0045995 71 0.015
negative regulation of organelle organization GO:0010639 90 0.015
epidermis development GO:0008544 187 0.015
negative regulation of protein phosphorylation GO:0001933 126 0.015
epithelial cell migration GO:0010631 63 0.015
sensory perception of chemical stimulus GO:0007606 51 0.015
negative regulation of nervous system development GO:0051961 156 0.015
positive regulation of kinase activity GO:0033674 155 0.015
cell chemotaxis GO:0060326 81 0.015
Mouse
regulation of reactive oxygen species metabolic process GO:2000377 40 0.015
small molecule biosynthetic process GO:0044283 132 0.015
regulation of transforming growth factor beta receptor signaling pathway GO:0017015 43 0.015
embryonic epithelial tube formation GO:0001838 130 0.015
carbohydrate derivative biosynthetic process GO:1901137 183 0.015
morphogenesis of an epithelial sheet GO:0002011 27 0.014
plasma membrane organization GO:0007009 90 0.014
ear development GO:0043583 200 0.014
cellular response to dna damage stimulus GO:0006974 207 0.014
mesoderm formation GO:0001707 62 0.014
bone development GO:0060348 120 0.014
cation homeostasis GO:0055080 212 0.014
Mouse Fly
potassium ion transmembrane transport GO:0071805 43 0.014
Mouse
epithelial cell proliferation GO:0050673 174 0.014
male sex differentiation GO:0046661 109 0.014
developmental maturation GO:0021700 193 0.014
nephrogenic mesenchyme development GO:0072076 3 0.014
muscle contraction GO:0006936 101 0.014
regulation of cell projection organization GO:0031344 206 0.014
positive regulation of cell morphogenesis involved in differentiation GO:0010770 72 0.014
neuron apoptotic process GO:0051402 142 0.014
regulation of nucleotide catabolic process GO:0030811 122 0.014
regulation of peptidyl tyrosine phosphorylation GO:0050730 93 0.014
anion transmembrane transport GO:0098656 71 0.014
stem cell maintenance GO:0019827 130 0.014
regulation of cytoplasmic transport GO:1903649 112 0.014
negative regulation of cell development GO:0010721 169 0.013
lung alveolus development GO:0048286 45 0.013
myelination GO:0042552 74 0.013
salivary gland development GO:0007431 37 0.013
nucleoside monophosphate metabolic process GO:0009123 85 0.013
glial cell differentiation GO:0010001 131 0.013
regulation of vesicle mediated transport GO:0060627 139 0.013
positive regulation of cell projection organization GO:0031346 95 0.013
sequestering of calcium ion GO:0051208 18 0.013
positive regulation of leukocyte differentiation GO:1902107 86 0.013
regulation of anatomical structure size GO:0090066 178 0.013
endothelial cell migration GO:0043542 44 0.013
positive regulation of response to wounding GO:1903036 66 0.013
negative regulation of cell migration GO:0030336 59 0.013
neuronal action potential GO:0019228 54 0.013
sterol homeostasis GO:0055092 45 0.013
regulation of secretion by cell GO:1903530 249 0.013
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.013
regulation of steroid metabolic process GO:0019218 39 0.013
prostate gland development GO:0030850 48 0.013
positive regulation of secretion GO:0051047 130 0.013
chromatin organization GO:0006325 206 0.013
positive regulation of gtpase activity GO:0043547 85 0.013
lung morphogenesis GO:0060425 50 0.013
leukocyte homeostasis GO:0001776 79 0.013
ear morphogenesis GO:0042471 118 0.013
positive regulation of nucleotide metabolic process GO:0045981 114 0.013
defense response to bacterium GO:0042742 119 0.013
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.013
negative regulation of transferase activity GO:0051348 85 0.013
positive regulation of purine nucleotide catabolic process GO:0033123 88 0.013
cell cycle switching GO:0060184 1 0.013
multicellular organismal homeostasis GO:0048871 164 0.013
metencephalon development GO:0022037 89 0.013
positive regulation of mapk cascade GO:0043410 170 0.013
oogenesis GO:0048477 56 0.013
negative regulation of neuron differentiation GO:0045665 101 0.013
hematopoietic progenitor cell differentiation GO:0002244 143 0.012
positive regulation of wnt signaling pathway GO:0030177 45 0.012
multi multicellular organism process GO:0044706 109 0.012
ribonucleoside monophosphate metabolic process GO:0009161 80 0.012
positive regulation of nucleoside metabolic process GO:0045979 91 0.012
cartilage development GO:0051216 140 0.012
purine nucleoside monophosphate metabolic process GO:0009126 81 0.012
positive regulation of gtp catabolic process GO:0033126 85 0.012
regulation of cysteine type endopeptidase activity GO:2000116 65 0.012
positive regulation of map kinase activity GO:0043406 84 0.012
exocytosis GO:0006887 121 0.012
negative regulation of cell fate specification GO:0009996 4 0.012
actin filament organization GO:0007015 113 0.012
cardiac chamber development GO:0003205 108 0.012
cardiac muscle tissue development GO:0048738 130 0.012
protein targeting GO:0006605 143 0.012
regulation of ras protein signal transduction GO:0046578 114 0.012
establishment or maintenance of cell polarity GO:0007163 86 0.012
cell cell adhesion via plasma membrane adhesion molecules GO:0098742 40 0.012
regulation of canonical wnt signaling pathway GO:0060828 82 0.012
response to inorganic substance GO:0010035 96 0.012
symbiosis encompassing mutualism through parasitism GO:0044403 83 0.012
development of primary female sexual characteristics GO:0046545 73 0.012
leukocyte activation involved in immune response GO:0002366 126 0.012
positive regulation of t cell activation GO:0050870 101 0.012
carboxylic acid biosynthetic process GO:0046394 86 0.012
embryonic appendage morphogenesis GO:0035113 126 0.012
male gonad development GO:0008584 88 0.012
positive regulation of protein catabolic process GO:0045732 60 0.012
muscle fiber development GO:0048747 76 0.012
nucleoside monophosphate catabolic process GO:0009125 59 0.012
negative regulation of mitotic cell cycle GO:0045930 58 0.012
regulation of striated muscle cell differentiation GO:0051153 81 0.012
microtubule based process GO:0007017 236 0.012
protein ubiquitination GO:0016567 171 0.012
regulation of protein localization GO:0032880 231 0.012
cardiocyte differentiation GO:0035051 87 0.012
primary neural tube formation GO:0014020 95 0.012
regulation of cardioblast differentiation GO:0051890 3 0.012
positive regulation of intracellular transport GO:0032388 70 0.012
negative regulation of cell motility GO:2000146 61 0.012
alpha beta t cell activation GO:0046631 91 0.012
organic hydroxy compound transport GO:0015850 93 0.011
cell type specific apoptotic process GO:0097285 268 0.011
protein localization to membrane GO:0072657 108 0.011
natural killer cell activation GO:0030101 44 0.011
sterol metabolic process GO:0016125 58 0.011
regulation of establishment of planar polarity GO:0090175 28 0.011
endocytosis GO:0006897 168 0.011

Trpm6 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.024
disease of cellular proliferation DOID:14566 0 0.024
organ system cancer DOID:0050686 0 0.024
disease of anatomical entity DOID:7 0 0.015
musculoskeletal system disease DOID:17 0 0.015