Mus musculus

50 known processes

Trpm7

transient receptor potential cation channel, subfamily M, member 7

(Aliases: 4833414K03Rik,Ltpr7,CHAK,TRPPLIK,Ltrpc7,CHAK1,2310022G15Rik,LTrpC-7,5033407O22Rik)

Trpm7 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of cell cycle GO:0051726 281 0.288
Zebrafish
modification dependent protein catabolic process GO:0019941 133 0.208
organic cyclic compound catabolic process GO:1901361 295 0.203
cation homeostasis GO:0055080 212 0.155
Zebrafish Mouse Rat Fly
cellular nitrogen compound catabolic process GO:0044270 280 0.148
hematopoietic progenitor cell differentiation GO:0002244 143 0.133
cellular chemical homeostasis GO:0055082 215 0.131
Mouse Rat
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.127
ion transmembrane transport GO:0034220 361 0.123
modification dependent macromolecule catabolic process GO:0043632 133 0.116
protein catabolic process GO:0030163 221 0.114
cellular metal ion homeostasis GO:0006875 151 0.110
Mouse Rat
protein modification by small protein conjugation GO:0032446 187 0.108
atp catabolic process GO:0006200 55 0.105
embryonic epithelial tube formation GO:0001838 130 0.101
nucleoside monophosphate metabolic process GO:0009123 85 0.100
cell division GO:0051301 120 0.099
neural tube formation GO:0001841 108 0.094
purine nucleotide metabolic process GO:0006163 302 0.087
cellular homeostasis GO:0019725 240 0.085
Mouse Rat
gonad development GO:0008406 141 0.084
Worm
macromolecule catabolic process GO:0009057 281 0.084
mitotic cell cycle GO:0000278 195 0.075
Zebrafish Worm
inorganic ion transmembrane transport GO:0098660 234 0.075
inorganic cation transmembrane transport GO:0098662 207 0.074
metencephalon development GO:0022037 89 0.072
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.071
chromatin organization GO:0006325 206 0.070
regulation of cellular ketone metabolic process GO:0010565 66 0.069
ubiquitin dependent protein catabolic process GO:0006511 129 0.069
histone modification GO:0016570 159 0.062
regulation of ion transport GO:0043269 215 0.062
cellular ketone metabolic process GO:0042180 84 0.062
purine ribonucleoside metabolic process GO:0046128 241 0.062
cellular amino acid metabolic process GO:0006520 103 0.062
regulation of organelle organization GO:0033043 289 0.061
calcium ion homeostasis GO:0055074 127 0.059
Mouse
cation transport GO:0006812 399 0.059
actin filament based movement GO:0030048 23 0.059
regulation of cell cycle process GO:0010564 160 0.059
atp metabolic process GO:0046034 75 0.058
aromatic compound catabolic process GO:0019439 286 0.056
cation transmembrane transport GO:0098655 266 0.055
glycosyl compound metabolic process GO:1901657 246 0.055
cellular response to dna damage stimulus GO:0006974 207 0.055
glycoprotein metabolic process GO:0009100 116 0.055
chromatin modification GO:0016568 187 0.053
ribonucleoside monophosphate metabolic process GO:0009161 80 0.053
divalent inorganic cation homeostasis GO:0072507 138 0.052
Zebrafish Mouse Rat Fly
angiogenesis GO:0001525 201 0.051
purine ribonucleotide metabolic process GO:0009150 290 0.050
calcium ion transport GO:0006816 159 0.050
multicellular organism growth GO:0035264 161 0.050
amine metabolic process GO:0009308 45 0.049
cellular protein catabolic process GO:0044257 155 0.049
organophosphate catabolic process GO:0046434 232 0.047
cellular amine metabolic process GO:0044106 44 0.045
nucleoside catabolic process GO:0009164 206 0.045
regulation of mitotic cell cycle GO:0007346 126 0.042
Zebrafish
covalent chromatin modification GO:0016569 163 0.042
primary neural tube formation GO:0014020 95 0.041
blood circulation GO:0008015 195 0.041
Zebrafish
oxidation reduction process GO:0055114 342 0.041
forebrain development GO:0030900 302 0.041
positive regulation of cellular catabolic process GO:0031331 148 0.041
purine nucleoside monophosphate catabolic process GO:0009128 58 0.040
maintenance of location GO:0051235 89 0.039
nucleoside monophosphate catabolic process GO:0009125 59 0.039
purine ribonucleoside monophosphate catabolic process GO:0009169 57 0.039
wound healing GO:0042060 157 0.039
regulation of mesenchymal cell proliferation involved in lung development GO:2000790 2 0.039
cellular macromolecule catabolic process GO:0044265 206 0.039
purine nucleoside monophosphate metabolic process GO:0009126 81 0.038
response to lipopolysaccharide GO:0032496 128 0.038
hindbrain development GO:0030902 128 0.036
metal ion homeostasis GO:0055065 189 0.036
Mouse Rat Fly
myeloid cell differentiation GO:0030099 233 0.034
purine nucleoside catabolic process GO:0006152 205 0.034
response to inorganic substance GO:0010035 96 0.034
tube formation GO:0035148 140 0.034
meiotic cell cycle GO:0051321 122 0.034
striated muscle tissue development GO:0014706 293 0.033
heterocycle catabolic process GO:0046700 280 0.033
negative regulation of mitotic cell cycle phase transition GO:1901991 45 0.033
organic anion transport GO:0015711 137 0.032
purine nucleotide catabolic process GO:0006195 211 0.032
rna processing GO:0006396 105 0.032
organelle localization GO:0051640 179 0.032
epithelial tube formation GO:0072175 130 0.031
organelle fission GO:0048285 170 0.030
Worm
regulation of chromatin silencing GO:0031935 2 0.030
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 40 0.030
negative regulation of cell cycle GO:0045786 123 0.029
nuclear division GO:0000280 158 0.029
Worm
carbohydrate derivative biosynthetic process GO:1901137 183 0.029
purine containing compound metabolic process GO:0072521 311 0.029
organic hydroxy compound metabolic process GO:1901615 203 0.029
Zebrafish
compound eye development GO:0048749 1 0.029
nucleoside triphosphate catabolic process GO:0009143 205 0.028
posttranscriptional regulation of gene expression GO:0010608 155 0.028
regulation of embryonic development GO:0045995 71 0.028
purine nucleoside metabolic process GO:0042278 241 0.028
ribonucleotide catabolic process GO:0009261 208 0.028
tube closure GO:0060606 91 0.028
negative regulation of cell cycle phase transition GO:1901988 48 0.027
cellular response to lipid GO:0071396 145 0.026
purine containing compound catabolic process GO:0072523 213 0.026
regulation of ion transmembrane transport GO:0034765 119 0.026
ribonucleoside monophosphate catabolic process GO:0009158 57 0.026
cell cycle g1 s phase transition GO:0044843 57 0.026
ribonucleotide metabolic process GO:0009259 291 0.026
protein modification by small protein conjugation or removal GO:0070647 207 0.026
intracellular protein transport GO:0006886 204 0.026
regulation of cell cycle phase transition GO:1901987 77 0.026
carbohydrate derivative catabolic process GO:1901136 231 0.026
lateral inhibition GO:0046331 1 0.025
myotube differentiation GO:0014902 105 0.025
neural tube closure GO:0001843 90 0.025
negative regulation of protein metabolic process GO:0051248 282 0.025
gland development GO:0048732 330 0.025
positive regulation of endocytosis GO:0045807 42 0.025
nucleoside phosphate catabolic process GO:1901292 222 0.025
retina development in camera type eye GO:0060041 119 0.025
transmembrane transport GO:0055085 412 0.024
mitotic nuclear division GO:0007067 48 0.024
Worm
ribonucleoside metabolic process GO:0009119 245 0.024
nucleoside phosphate metabolic process GO:0006753 338 0.024
regulation of cell activation GO:0050865 289 0.024
epidermis development GO:0008544 187 0.024
positive regulation of hydrolase activity GO:0051345 148 0.024
positive regulation of proteolysis GO:0045862 85 0.024
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.024
camera type eye development GO:0043010 266 0.023
nucleotide catabolic process GO:0009166 217 0.023
regulation of cellular catabolic process GO:0031329 242 0.023
multi multicellular organism process GO:0044706 109 0.023
protein maturation GO:0051604 176 0.023
ribonucleoside triphosphate metabolic process GO:0009199 220 0.023
response to radiation GO:0009314 165 0.023
Mouse Rat
nucleoside triphosphate metabolic process GO:0009141 230 0.022
sensory organ morphogenesis GO:0090596 242 0.022
Mouse
gene silencing GO:0016458 38 0.022
muscle contraction GO:0006936 101 0.022
positive regulation of organelle organization GO:0010638 128 0.022
cell type specific apoptotic process GO:0097285 268 0.022
oocyte axis specification GO:0007309 2 0.022
regulation of homeostatic process GO:0032844 182 0.022
regulation of metal ion transport GO:0010959 106 0.022
regulation of cellular amino acid metabolic process GO:0006521 5 0.022
spermatogenesis GO:0007283 284 0.022
microtubule cytoskeleton organization GO:0000226 157 0.022
negative regulation of protein modification process GO:0031400 163 0.021
response to arsenic containing substance GO:0046685 5 0.021
regulation of translation GO:0006417 71 0.021
purine ribonucleotide catabolic process GO:0009154 208 0.021
regulation of neuron differentiation GO:0045664 281 0.021
genitalia development GO:0048806 37 0.021
Worm
regionalization GO:0003002 337 0.021
homeostasis of number of cells GO:0048872 210 0.021
nucleobase containing small molecule metabolic process GO:0055086 352 0.021
negative regulation of cellular protein metabolic process GO:0032269 247 0.021
regulation of intracellular transport GO:0032386 159 0.021
myeloid leukocyte differentiation GO:0002573 119 0.021
negative regulation of phosphorus metabolic process GO:0010563 184 0.021
axonogenesis GO:0007409 274 0.021
organelle assembly GO:0070925 177 0.020
purine ribonucleoside catabolic process GO:0046130 205 0.020
neurotransmitter secretion GO:0007269 62 0.020
Zebrafish
proteasomal protein catabolic process GO:0010498 98 0.020
actin mediated cell contraction GO:0070252 15 0.020
nucleotide metabolic process GO:0009117 332 0.020
muscle cell differentiation GO:0042692 261 0.020
positive regulation of myeloid cell apoptotic process GO:0033034 4 0.020
negative regulation of molecular function GO:0044092 258 0.020
peptidyl amino acid modification GO:0018193 336 0.020
cellular response to hormone stimulus GO:0032870 150 0.020
stem cell maintenance GO:0019827 130 0.019
muscle system process GO:0003012 141 0.019
cochlear nucleus development GO:0021747 4 0.019
positive regulation of cell cycle process GO:0090068 61 0.019
regulation of transmembrane transport GO:0034762 128 0.019
inner ear receptor cell differentiation GO:0060113 61 0.019
cellular response to insulin stimulus GO:0032869 78 0.019
sodium ion transport GO:0006814 73 0.019
Mouse
divalent inorganic cation transport GO:0072511 178 0.019
neural tube development GO:0021915 160 0.019
regulation of proteolysis GO:0030162 164 0.019
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.019
purine nucleoside triphosphate metabolic process GO:0009144 226 0.019
protein processing GO:0016485 163 0.018
negative regulation of cellular amine metabolic process GO:0033239 1 0.018
microtubule anchoring at microtubule organizing center GO:0072393 5 0.018
response to testosterone GO:0033574 3 0.018
small gtpase mediated signal transduction GO:0007264 97 0.018
cellular ion homeostasis GO:0006873 165 0.018
Mouse Rat
ear development GO:0043583 200 0.018
protein localization to organelle GO:0033365 185 0.018
regulation of protein localization GO:0032880 231 0.018
t cell activation GO:0042110 289 0.018
phagocytosis GO:0006909 66 0.018
leukocyte proliferation GO:0070661 172 0.018
organonitrogen compound catabolic process GO:1901565 264 0.018
regulation of membrane potential GO:0042391 192 0.018
cardiocyte differentiation GO:0035051 87 0.018
protein polymerization GO:0051258 57 0.018
regulation of mitotic cell cycle phase transition GO:1901990 73 0.017
translation GO:0006412 93 0.017
muscle tissue development GO:0060537 308 0.017
development of primary sexual characteristics GO:0045137 143 0.017
Worm
protein oligomerization GO:0051259 67 0.017
Mouse
apoptotic signaling pathway GO:0097190 306 0.017
negative regulation of cell proliferation GO:0008285 296 0.017
positive regulation of cellular amine metabolic process GO:0033240 5 0.017
cellular divalent inorganic cation homeostasis GO:0072503 127 0.017
Mouse Rat
blastocyst development GO:0001824 80 0.017
interkinetic nuclear migration GO:0022027 8 0.017
neural nucleus development GO:0048857 22 0.017
female gamete generation GO:0007292 74 0.017
potassium ion transport GO:0006813 52 0.016
Mouse
negative regulation of protein processing GO:0010955 79 0.016
response to uv GO:0009411 44 0.016
meiotic nuclear division GO:0007126 115 0.016
establishment of organelle localization GO:0051656 122 0.016
ribonucleoside triphosphate catabolic process GO:0009203 199 0.016
cell aging GO:0007569 35 0.016
ribose phosphate metabolic process GO:0019693 291 0.016
synaptic transmission GO:0007268 329 0.015
Zebrafish
lipid localization GO:0010876 126 0.015
response to molecule of bacterial origin GO:0002237 143 0.015
negative regulation of mesenchymal cell proliferation GO:0072201 3 0.015
lymphocyte differentiation GO:0030098 242 0.015
germ cell development GO:0007281 185 0.015
regulation of cytokine production GO:0001817 266 0.015
bone development GO:0060348 120 0.015
regulation of apoptotic signaling pathway GO:2001233 197 0.014
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.014
chemotaxis GO:0006935 247 0.014
Mouse
action potential GO:0001508 78 0.014
monovalent inorganic cation homeostasis GO:0055067 33 0.014
regulation of calcium ion transport into cytosol GO:0010522 31 0.014
morphogenesis of embryonic epithelium GO:0016331 159 0.014
regulation of protein maturation GO:1903317 96 0.014
regulation of protein transport GO:0051223 163 0.014
auditory receptor cell differentiation GO:0042491 37 0.014
response to light stimulus GO:0009416 135 0.014
Mouse
ribonucleoside catabolic process GO:0042454 206 0.014
negative regulation of protein maturation GO:1903318 79 0.014
neuronal action potential GO:0019228 54 0.014
cellular response to organonitrogen compound GO:0071417 145 0.014
cytokine production GO:0001816 319 0.014
nitrogen compound transport GO:0071705 271 0.013
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.013
ossification GO:0001503 216 0.013
Zebrafish
negative regulation of mitotic cell cycle GO:0045930 58 0.013
regulation of ketone biosynthetic process GO:0010566 2 0.013
monocyte differentiation GO:0030224 9 0.013
anion transport GO:0006820 177 0.013
megakaryocyte differentiation GO:0030219 26 0.013
peptidyl serine phosphorylation GO:0018105 74 0.013
neuron migration GO:0001764 122 0.013
adaptive immune response GO:0002250 155 0.013
circulatory system process GO:0003013 197 0.013
Zebrafish
purine nucleoside triphosphate catabolic process GO:0009146 203 0.013
positive regulation of protein phosphorylation GO:0001934 242 0.013
protein ubiquitination GO:0016567 171 0.013
developmental growth involved in morphogenesis GO:0060560 138 0.013
steroid metabolic process GO:0008202 119 0.013
regulation of cytoplasmic transport GO:1903649 112 0.013
leukocyte differentiation GO:0002521 342 0.013
negative regulation of phosphate metabolic process GO:0045936 184 0.012
cardiac muscle tissue development GO:0048738 130 0.012
cellular response to steroid hormone stimulus GO:0071383 33 0.012
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.012
negative regulation of protein phosphorylation GO:0001933 126 0.012
skin development GO:0043588 220 0.012
regulation of protein processing GO:0070613 96 0.012
nucleus localization GO:0051647 20 0.012
skeletal system development GO:0001501 356 0.012
Zebrafish
regulation of stem cell proliferation GO:0072091 78 0.012
cellular response to abiotic stimulus GO:0071214 56 0.012
Mouse
dna metabolic process GO:0006259 303 0.012
pharynx development GO:0060465 1 0.012
cellular response to lipopolysaccharide GO:0071222 77 0.012
vacuole organization GO:0007033 38 0.012
meiotic cell cycle process GO:1903046 77 0.012
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.012
nucleoside metabolic process GO:0009116 246 0.012
central nervous system neuron differentiation GO:0021953 162 0.012
retina morphogenesis in camera type eye GO:0060042 45 0.012
learning or memory GO:0007611 148 0.012
Rat
extrinsic apoptotic signaling pathway GO:0097191 126 0.012
negative regulation of translation GO:0017148 22 0.012
response to growth factor GO:0070848 198 0.012
rna interference GO:0016246 2 0.011
cytoplasmic transport GO:0016482 234 0.011
defense response to other organism GO:0098542 197 0.011
regulation of protein ubiquitination GO:0031396 52 0.011
regulation of cellular response to stress GO:0080135 159 0.011
oocyte construction GO:0007308 2 0.011
signal transduction by p53 class mediator GO:0072331 51 0.011
cellular protein complex assembly GO:0043623 116 0.011
regulation of establishment of protein localization GO:0070201 181 0.011
endocytosis GO:0006897 168 0.011
mitotic cell cycle process GO:1903047 159 0.011
Worm
positive regulation of protein modification process GO:0031401 299 0.011
cellularization GO:0007349 1 0.011
ras protein signal transduction GO:0007265 77 0.011
mrna metabolic process GO:0016071 84 0.011
respiratory system development GO:0060541 190 0.011
granulocyte differentiation GO:0030851 17 0.011
intrinsic apoptotic signaling pathway GO:0097193 132 0.011
hydrogen ion transmembrane transport GO:1902600 25 0.011
glycoprotein biosynthetic process GO:0009101 89 0.011
cell adhesion GO:0007155 329 0.011
endoderm development GO:0007492 45 0.011
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.011
nuclear import GO:0051170 95 0.011
regulation of intracellular protein transport GO:0033157 82 0.011
glycosyl compound catabolic process GO:1901658 206 0.011
bone morphogenesis GO:0060349 78 0.011
cell proliferation in forebrain GO:0021846 30 0.010
establishment of rna localization GO:0051236 18 0.010
regulation of isoprenoid metabolic process GO:0019747 1 0.010
carboxylic acid biosynthetic process GO:0046394 86 0.010
nucleocytoplasmic transport GO:0006913 139 0.010
regulation of protein catabolic process GO:0042176 108 0.010
positive regulation of ion transport GO:0043270 65 0.010
skeletal system morphogenesis GO:0048705 203 0.010
regulation of neurotransmitter levels GO:0001505 87 0.010
Zebrafish
positive regulation of homeostatic process GO:0032846 64 0.010
blood vessel morphogenesis GO:0048514 285 0.010
regulation of lymphocyte activation GO:0051249 240 0.010
negative regulation of cell cycle process GO:0010948 69 0.010
histone lysine demethylation GO:0070076 13 0.010
positive regulation of fatty acid biosynthetic process GO:0045723 3 0.010

Trpm7 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
nephritis DOID:10952 0 0.101
glomerulonephritis DOID:2921 0 0.101
focal segmental glomerulosclerosis DOID:1312 0 0.101
kidney disease DOID:557 0 0.101
disease of anatomical entity DOID:7 0 0.101
urinary system disease DOID:18 0 0.101
glomerulosclerosis DOID:0050851 0 0.101
nervous system disease DOID:863 0 0.066
sensory system disease DOID:0050155 0 0.040
cancer DOID:162 0 0.032
disease of cellular proliferation DOID:14566 0 0.032
organ system cancer DOID:0050686 0 0.032
endocrine gland cancer DOID:170 0 0.017