Mus musculus

28 known processes

Srd5a1

steroid 5 alpha-reductase 1

(Aliases: S5AR 1,4930435F02Rik,0610031P22Rik,Srd5a-1)

Srd5a1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular amino acid metabolic process GO:0006520 103 0.080
amine metabolic process GO:0009308 45 0.067
cellular amine metabolic process GO:0044106 44 0.063
regulation of cellular amino acid metabolic process GO:0006521 5 0.062
cellular lipid metabolic process GO:0044255 323 0.052
Rat
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.049
regulation of cellular ketone metabolic process GO:0010565 66 0.045
nucleoside phosphate metabolic process GO:0006753 338 0.043
nucleoside metabolic process GO:0009116 246 0.042
cellular ketone metabolic process GO:0042180 84 0.040
Rat
cell adhesion GO:0007155 329 0.040
nucleobase containing small molecule metabolic process GO:0055086 352 0.039
purine ribonucleotide metabolic process GO:0009150 290 0.039
transmembrane transport GO:0055085 412 0.038
regulation of cellular amine metabolic process GO:0033238 20 0.038
nucleotide metabolic process GO:0009117 332 0.038
ras protein signal transduction GO:0007265 77 0.037
purine containing compound metabolic process GO:0072521 311 0.035
glycosyl compound metabolic process GO:1901657 246 0.034
ribonucleotide metabolic process GO:0009259 291 0.034
purine ribonucleoside metabolic process GO:0046128 241 0.034
ribose phosphate metabolic process GO:0019693 291 0.034
aromatic compound catabolic process GO:0019439 286 0.033
purine nucleoside metabolic process GO:0042278 241 0.033
organic cyclic compound catabolic process GO:1901361 295 0.031
oxidation reduction process GO:0055114 342 0.031
ion transmembrane transport GO:0034220 361 0.031
gland development GO:0048732 330 0.030
Rat
cellular nitrogen compound catabolic process GO:0044270 280 0.030
ribonucleoside metabolic process GO:0009119 245 0.029
positive regulation of cellular amine metabolic process GO:0033240 5 0.029
regulation of organelle organization GO:0033043 289 0.029
heterocycle catabolic process GO:0046700 280 0.029
purine nucleotide metabolic process GO:0006163 302 0.029
nitrogen compound transport GO:0071705 271 0.028
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.028
nucleoside triphosphate metabolic process GO:0009141 230 0.027
protein modification by small protein conjugation GO:0032446 187 0.026
small gtpase mediated signal transduction GO:0007264 97 0.026
negative regulation of cell proliferation GO:0008285 296 0.026
carbohydrate derivative biosynthetic process GO:1901137 183 0.026
peptidyl amino acid modification GO:0018193 336 0.026
carbohydrate derivative catabolic process GO:1901136 231 0.026
regulation of hormone levels GO:0010817 211 0.025
regulation of cellular catabolic process GO:0031329 242 0.025
macromolecule catabolic process GO:0009057 281 0.025
spermatogenesis GO:0007283 284 0.025
lipid biosynthetic process GO:0008610 179 0.024
organonitrogen compound catabolic process GO:1901565 264 0.024
cation transport GO:0006812 399 0.024
glycosyl compound catabolic process GO:1901658 206 0.024
urogenital system development GO:0001655 261 0.024
Rat
ribonucleoside triphosphate metabolic process GO:0009199 220 0.024
purine ribonucleotide catabolic process GO:0009154 208 0.024
nucleotide catabolic process GO:0009166 217 0.023
negative regulation of cellular protein metabolic process GO:0032269 247 0.023
purine nucleoside catabolic process GO:0006152 205 0.023
purine ribonucleoside catabolic process GO:0046130 205 0.023
organonitrogen compound biosynthetic process GO:1901566 192 0.023
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.023
negative regulation of molecular function GO:0044092 258 0.023
organic hydroxy compound metabolic process GO:1901615 203 0.023
Rat
protein modification by small protein conjugation or removal GO:0070647 207 0.023
positive regulation of protein modification process GO:0031401 299 0.023
positive regulation of protein phosphorylation GO:0001934 242 0.022
alcohol metabolic process GO:0006066 116 0.022
synaptic transmission GO:0007268 329 0.022
regulation of cell activation GO:0050865 289 0.022
forebrain development GO:0030900 302 0.022
Rat
cellular alcohol biosynthetic process GO:0044108 3 0.022
nucleoside triphosphate catabolic process GO:0009143 205 0.022
epithelial tube morphogenesis GO:0060562 303 0.022
apoptotic signaling pathway GO:0097190 306 0.022
male gamete generation GO:0048232 285 0.022
negative regulation of protein metabolic process GO:0051248 282 0.021
protein ubiquitination GO:0016567 171 0.021
purine nucleotide catabolic process GO:0006195 211 0.021
purine nucleoside triphosphate metabolic process GO:0009144 226 0.021
posttranscriptional regulation of gene expression GO:0010608 155 0.021
ribonucleoside triphosphate catabolic process GO:0009203 199 0.021
purine nucleoside triphosphate catabolic process GO:0009146 203 0.021
rho protein signal transduction GO:0007266 32 0.021
nucleoside phosphate catabolic process GO:1901292 222 0.020
mapk cascade GO:0000165 281 0.020
regulation of transferase activity GO:0051338 263 0.020
ribonucleotide catabolic process GO:0009261 208 0.020
ribonucleoside catabolic process GO:0042454 206 0.020
purine containing compound catabolic process GO:0072523 213 0.020
inorganic ion transmembrane transport GO:0098660 234 0.019
cellular homeostasis GO:0019725 240 0.019
single organism cell adhesion GO:0098602 156 0.019
small molecule biosynthetic process GO:0044283 132 0.019
embryonic epithelial tube formation GO:0001838 130 0.018
microtubule based process GO:0007017 236 0.018
regulation of kinase activity GO:0043549 249 0.018
cellular chemical homeostasis GO:0055082 215 0.018
neuron death GO:0070997 154 0.018
skin development GO:0043588 220 0.018
nucleoside catabolic process GO:0009164 206 0.018
negative regulation of cellular component organization GO:0051129 194 0.018
inorganic cation transmembrane transport GO:0098662 207 0.018
regulation of neuron differentiation GO:0045664 281 0.018
regulation of cytokine production GO:0001817 266 0.018
cell type specific apoptotic process GO:0097285 268 0.018
regulation of cell cycle GO:0051726 281 0.017
positive regulation of cell development GO:0010720 237 0.017
organophosphate catabolic process GO:0046434 232 0.017
positive regulation of cell death GO:0010942 224 0.017
regulation of membrane potential GO:0042391 192 0.017
cellular response to hormone stimulus GO:0032870 150 0.017
Rat
carbohydrate metabolic process GO:0005975 230 0.017
positive regulation of apoptotic process GO:0043065 217 0.017
cellular response to organonitrogen compound GO:0071417 145 0.017
Rat
negative regulation of phosphate metabolic process GO:0045936 184 0.017
response to organonitrogen compound GO:0010243 246 0.017
Rat
membrane organization GO:0061024 245 0.017
regulation of protein kinase activity GO:0045859 232 0.017
g protein coupled receptor signaling pathway GO:0007186 243 0.017
regulation of cell adhesion GO:0030155 154 0.017
cytokine production GO:0001816 319 0.017
sensory perception GO:0007600 245 0.017
regulation of mapk cascade GO:0043408 248 0.017
carboxylic acid biosynthetic process GO:0046394 86 0.017
cation transmembrane transport GO:0098655 266 0.017
camera type eye development GO:0043010 266 0.016
regulation of hydrolase activity GO:0051336 246 0.016
protein catabolic process GO:0030163 221 0.016
protein maturation GO:0051604 176 0.016
anion transport GO:0006820 177 0.016
sulfur compound metabolic process GO:0006790 100 0.016
negative regulation of cellular amine metabolic process GO:0033239 1 0.016
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.016
blood vessel morphogenesis GO:0048514 285 0.016
wound healing GO:0042060 157 0.016
t cell activation GO:0042110 289 0.016
regulation of purine nucleotide metabolic process GO:1900542 169 0.016
regulation of cellular component biogenesis GO:0044087 181 0.016
steroid metabolic process GO:0008202 119 0.016
dna metabolic process GO:0006259 303 0.015
ossification GO:0001503 216 0.015
regulation of purine nucleotide catabolic process GO:0033121 122 0.015
response to radiation GO:0009314 165 0.015
cellular response to dna damage stimulus GO:0006974 207 0.015
regulation of anatomical structure size GO:0090066 178 0.015
compound eye development GO:0048749 1 0.015
negative regulation of phosphorus metabolic process GO:0010563 184 0.015
cytoplasmic transport GO:0016482 234 0.015
organelle fission GO:0048285 170 0.015
epidermis development GO:0008544 187 0.015
cellular alcohol metabolic process GO:0044107 3 0.015
organic acid biosynthetic process GO:0016053 86 0.015
positive regulation of hydrolase activity GO:0051345 148 0.015
cation homeostasis GO:0055080 212 0.015
monocarboxylic acid metabolic process GO:0032787 191 0.015
reactive oxygen species metabolic process GO:0072593 84 0.014
locomotory behavior GO:0007626 195 0.014
intracellular protein transport GO:0006886 204 0.014
hormone secretion GO:0046879 128 0.014
negative regulation of intracellular signal transduction GO:1902532 167 0.014
adult behavior GO:0030534 135 0.014
amide transport GO:0042886 138 0.014
striated muscle tissue development GO:0014706 293 0.014
chemotaxis GO:0006935 247 0.014
cellular macromolecule catabolic process GO:0044265 206 0.014
developmental maturation GO:0021700 193 0.014
glycerolipid metabolic process GO:0046486 122 0.014
epithelial cell proliferation GO:0050673 174 0.014
metal ion homeostasis GO:0055065 189 0.014
positive regulation of programmed cell death GO:0043068 218 0.014
response to organic cyclic compound GO:0014070 198 0.014
Rat
neural tube development GO:0021915 160 0.014
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.014
positive regulation of transferase activity GO:0051347 167 0.014
regulation of homeostatic process GO:0032844 182 0.014
cognition GO:0050890 149 0.014
organophosphate biosynthetic process GO:0090407 122 0.014
placenta development GO:0001890 140 0.014
regulation of cell projection organization GO:0031344 206 0.014
regulation of lymphocyte activation GO:0051249 240 0.014
b cell activation GO:0042113 161 0.014
regulation of ion transport GO:0043269 215 0.014
regulation of cellular response to stress GO:0080135 159 0.014
gtp metabolic process GO:0046039 144 0.014
spermatid development GO:0007286 108 0.014
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.014
transmission of nerve impulse GO:0019226 76 0.014
morphogenesis of embryonic epithelium GO:0016331 159 0.014
positive regulation of cellular catabolic process GO:0031331 148 0.013
renal system development GO:0072001 225 0.013
divalent inorganic cation transport GO:0072511 178 0.013
extracellular matrix organization GO:0030198 147 0.013
kidney development GO:0001822 213 0.013
glycoprotein metabolic process GO:0009100 116 0.013
regulation of transmembrane transport GO:0034762 128 0.013
cell substrate adhesion GO:0031589 130 0.013
leukocyte proliferation GO:0070661 172 0.013
cellular ion homeostasis GO:0006873 165 0.013
microtubule cytoskeleton organization GO:0000226 157 0.013
negative regulation of cell development GO:0010721 169 0.013
respiratory tube development GO:0030323 167 0.013
multicellular organism growth GO:0035264 161 0.013
regulation of cellular component size GO:0032535 121 0.013
divalent metal ion transport GO:0070838 172 0.013
regulation of ion transmembrane transport GO:0034765 119 0.013
endomembrane system organization GO:0010256 147 0.013
nuclear division GO:0000280 158 0.013
methylation GO:0032259 134 0.013
organelle localization GO:0051640 179 0.013
organelle assembly GO:0070925 177 0.013
lateral inhibition GO:0046331 1 0.013
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.013
respiratory system development GO:0060541 190 0.013
fatty acid metabolic process GO:0006631 121 0.013
peptide transport GO:0015833 133 0.013
neuron apoptotic process GO:0051402 142 0.013
regulation of secretion GO:0051046 274 0.013
retrograde transport endosome to golgi GO:0042147 2 0.013
circulatory system process GO:0003013 197 0.013
nucleoside monophosphate metabolic process GO:0009123 85 0.013
multicellular organismal homeostasis GO:0048871 164 0.013
guanosine containing compound catabolic process GO:1901069 144 0.013
embryonic organ morphogenesis GO:0048562 276 0.013
cellular response to lipid GO:0071396 145 0.013
Rat
angiogenesis GO:0001525 201 0.013
cellular protein complex assembly GO:0043623 116 0.012
maintenance of location GO:0051235 89 0.012
actin cytoskeleton organization GO:0030036 220 0.012
regulation of nucleotide catabolic process GO:0030811 122 0.012
epithelial cell development GO:0002064 159 0.012
regulation of nucleotide metabolic process GO:0006140 169 0.012
regulation of cytoskeleton organization GO:0051493 122 0.012
telencephalon development GO:0021537 186 0.012
Rat
regulation of apoptotic signaling pathway GO:2001233 197 0.012
stem cell differentiation GO:0048863 268 0.012
peptide secretion GO:0002790 114 0.012
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.012
lymphocyte proliferation GO:0046651 164 0.012
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.012
cell cell junction organization GO:0045216 72 0.012
digestive system development GO:0055123 200 0.012
regulation of neuron apoptotic process GO:0043523 122 0.012
regulation of mitotic cell cycle GO:0007346 126 0.012
wnt signaling pathway GO:0016055 188 0.012
response to growth factor GO:0070848 198 0.012
Rat
insulin secretion GO:0030073 89 0.012
purine nucleoside monophosphate metabolic process GO:0009126 81 0.012
hematopoietic progenitor cell differentiation GO:0002244 143 0.012
axonogenesis GO:0007409 274 0.012
protein localization to organelle GO:0033365 185 0.012
regulation of reactive oxygen species metabolic process GO:2000377 40 0.012
organic anion transport GO:0015711 137 0.012
positive regulation of nervous system development GO:0051962 221 0.012
negative regulation of apoptotic signaling pathway GO:2001234 104 0.012
protein targeting GO:0006605 143 0.012
regulation of feeding behavior GO:0060259 3 0.012
immune effector process GO:0002252 321 0.012
regulation of ras protein signal transduction GO:0046578 114 0.012
innate immune response GO:0045087 157 0.012
regionalization GO:0003002 337 0.012
regulation of neuron death GO:1901214 134 0.012
glucose homeostasis GO:0042593 128 0.012
regulation of cell migration GO:0030334 219 0.012
lymphocyte differentiation GO:0030098 242 0.012
gonad development GO:0008406 141 0.012
Rat
mitochondrion organization GO:0007005 134 0.012
cellular response to growth factor stimulus GO:0071363 197 0.012
Rat
positive regulation of protein kinase activity GO:0045860 144 0.012
rna interference GO:0016246 2 0.012
response to inorganic substance GO:0010035 96 0.012
midgut development GO:0007494 4 0.012
negative regulation of phosphorylation GO:0042326 166 0.012
response to peptide GO:1901652 136 0.011
Rat
leukocyte differentiation GO:0002521 342 0.011
negative regulation of immune system process GO:0002683 209 0.011
ribonucleoside monophosphate metabolic process GO:0009161 80 0.011
negative regulation of cell cycle GO:0045786 123 0.011
muscle tissue development GO:0060537 308 0.011
reactive nitrogen species metabolic process GO:2001057 0 0.011
gtp catabolic process GO:0006184 143 0.011
response to acid chemical GO:0001101 111 0.011
peptidyl tyrosine modification GO:0018212 145 0.011
regulation of proteolysis GO:0030162 164 0.011
regulation of secretion by cell GO:1903530 249 0.011
germ cell development GO:0007281 185 0.011
skeletal system development GO:0001501 356 0.011
Rat
positive regulation of mapk cascade GO:0043410 170 0.011
nuclear transport GO:0051169 139 0.011
positive regulation of gtp catabolic process GO:0033126 85 0.011
spermatid differentiation GO:0048515 115 0.011
tube formation GO:0035148 140 0.011
ear development GO:0043583 200 0.011
morphogenesis of a branching structure GO:0001763 203 0.011
regulation of cell size GO:0008361 72 0.011
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.011
skeletal system morphogenesis GO:0048705 203 0.011
connective tissue development GO:0061448 179 0.011
cellular protein catabolic process GO:0044257 155 0.011
extracellular structure organization GO:0043062 148 0.011
cholesterol metabolic process GO:0008203 56 0.011
modification dependent macromolecule catabolic process GO:0043632 133 0.011
cellular metal ion homeostasis GO:0006875 151 0.011
fat cell differentiation GO:0045444 160 0.011
cellular response to cytokine stimulus GO:0071345 189 0.011
oocyte construction GO:0007308 2 0.011
protein localization to membrane GO:0072657 108 0.011
regulation of nucleoside metabolic process GO:0009118 130 0.011
monosaccharide metabolic process GO:0005996 106 0.011
regulation of cell motility GO:2000145 236 0.011
regulation of epithelial cell proliferation GO:0050678 141 0.011
stem cell development GO:0048864 219 0.011
tissue homeostasis GO:0001894 115 0.011
regulation of protein serine threonine kinase activity GO:0071900 157 0.011
negative regulation of protein modification process GO:0031400 163 0.011
lipoprotein metabolic process GO:0042157 43 0.011
myosin filament assembly GO:0031034 2 0.011
single organismal cell cell adhesion GO:0016337 131 0.011
glycoprotein biosynthetic process GO:0009101 89 0.011
lung development GO:0030324 164 0.011
peptide hormone secretion GO:0030072 109 0.011
epithelial tube formation GO:0072175 130 0.011
learning or memory GO:0007611 148 0.011
monocarboxylic acid biosynthetic process GO:0072330 61 0.011
negative regulation of nervous system development GO:0051961 156 0.011
action potential GO:0001508 78 0.011
regulation of t cell activation GO:0050863 170 0.011
mrna metabolic process GO:0016071 84 0.011
guanosine containing compound metabolic process GO:1901068 144 0.010
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.010
sensory organ morphogenesis GO:0090596 242 0.010
regulation of gtp catabolic process GO:0033124 113 0.010
regulation of cell substrate adhesion GO:0010810 73 0.010
atp metabolic process GO:0046034 75 0.010
mitotic cell cycle GO:0000278 195 0.010
extrinsic apoptotic signaling pathway GO:0097191 126 0.010
multicellular organismal signaling GO:0035637 91 0.010
peptidyl tyrosine phosphorylation GO:0018108 143 0.010
dephosphorylation GO:0016311 129 0.010
carbohydrate homeostasis GO:0033500 128 0.010
skeletal muscle organ development GO:0060538 163 0.010
striated muscle myosin thick filament assembly GO:0071688 1 0.010
inflammatory response GO:0006954 244 0.010
organic hydroxy compound biosynthetic process GO:1901617 77 0.010
protein processing GO:0016485 163 0.010
cell growth GO:0016049 130 0.010

Srd5a1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
immune system disease DOID:2914 0 0.020
disease of anatomical entity DOID:7 0 0.020
disease of metabolism DOID:0014667 0 0.019
inherited metabolic disorder DOID:655 0 0.019
nervous system disease DOID:863 0 0.019
musculoskeletal system disease DOID:17 0 0.017
disease of cellular proliferation DOID:14566 0 0.015
organ system cancer DOID:0050686 0 0.014
cancer DOID:162 0 0.014
hematopoietic system disease DOID:74 0 0.013
connective tissue disease DOID:65 0 0.013
sensory system disease DOID:0050155 0 0.013
cardiovascular system disease DOID:1287 0 0.012