Mus musculus

15 known processes

Tifa

TRAF-interacting protein with forkhead-associated domain

(Aliases: T2bp)

Tifa biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
immune response regulating signaling pathway GO:0002764 125 0.529
response to molecule of bacterial origin GO:0002237 143 0.508
toll like receptor signaling pathway GO:0002224 38 0.493
cellular response to lipopolysaccharide GO:0071222 77 0.479
response to lipopolysaccharide GO:0032496 128 0.400
cellular response to biotic stimulus GO:0071216 92 0.399
regulation of toll like receptor signaling pathway GO:0034121 20 0.394
immune response activating signal transduction GO:0002757 116 0.354
lipopolysaccharide mediated signaling pathway GO:0031663 25 0.314
regulation of innate immune response GO:0045088 91 0.309
cellular response to molecule of bacterial origin GO:0071219 83 0.305
interleukin 1 mediated signaling pathway GO:0070498 4 0.299
positive regulation of innate immune response GO:0045089 80 0.291
activation of immune response GO:0002253 138 0.261
activation of nf kappab inducing kinase activity GO:0007250 4 0.253
activation of innate immune response GO:0002218 56 0.243
regulation of cytokine production GO:0001817 266 0.231
negative regulation of immune system process GO:0002683 209 0.228
leukocyte mediated immunity GO:0002443 174 0.214
adaptive immune response GO:0002250 155 0.209
regulation of cell activation GO:0050865 289 0.207
cytokine production involved in immune response GO:0002367 34 0.170
cellular response to lipid GO:0071396 145 0.163
immune effector process GO:0002252 321 0.156
regulation of defense response GO:0031347 233 0.152
lymphocyte mediated immunity GO:0002449 139 0.149
negative regulation of toll like receptor signaling pathway GO:0034122 14 0.149
innate immune response activating signal transduction GO:0002758 50 0.149
positive regulation of defense response GO:0031349 124 0.143
innate immune response GO:0045087 157 0.125
cytokine production GO:0001816 319 0.123
positive regulation of cell activation GO:0050867 158 0.121
mapk cascade GO:0000165 281 0.120
regulation of leukocyte mediated immunity GO:0002703 104 0.113
production of molecular mediator of immune response GO:0002440 103 0.108
regulation of lymphocyte activation GO:0051249 240 0.108
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.097
positive regulation of cellular amine metabolic process GO:0033240 5 0.095
regulation of transferase activity GO:0051338 263 0.094
t cell activation GO:0042110 289 0.094
b cell activation GO:0042113 161 0.089
stress activated protein kinase signaling cascade GO:0031098 81 0.089
regulation of mapk cascade GO:0043408 248 0.088
negative regulation of immune effector process GO:0002698 55 0.088
cell activation involved in immune response GO:0002263 126 0.086
positive regulation of jnk cascade GO:0046330 46 0.084
positive regulation of mapk cascade GO:0043410 170 0.083
regulation of cellular ketone metabolic process GO:0010565 66 0.082
regulation of protein serine threonine kinase activity GO:0071900 157 0.079
negative regulation of cytokine production GO:0001818 84 0.077
regulation of protein kinase activity GO:0045859 232 0.076
defense response to other organism GO:0098542 197 0.076
pattern recognition receptor signaling pathway GO:0002221 47 0.072
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.071
antigen processing and presentation GO:0019882 47 0.071
leukocyte activation involved in immune response GO:0002366 126 0.070
regulation of cellular amino acid metabolic process GO:0006521 5 0.069
cellular amine metabolic process GO:0044106 44 0.067
regulation of cytokine production involved in immune response GO:0002718 26 0.066
protein modification by small protein conjugation or removal GO:0070647 207 0.064
positive regulation of transferase activity GO:0051347 167 0.064
amine metabolic process GO:0009308 45 0.064
cellular response to cytokine stimulus GO:0071345 189 0.064
negative regulation of defense response GO:0031348 77 0.063
cellular amino acid metabolic process GO:0006520 103 0.062
toll like receptor 4 signaling pathway GO:0034142 9 0.062
positive regulation of interferon alpha production GO:0032727 4 0.062
positive regulation of stress activated mapk cascade GO:0032874 48 0.062
organic hydroxy compound transport GO:0015850 93 0.062
regulation of cellular response to stress GO:0080135 159 0.061
regulation of interleukin 6 production GO:0032675 55 0.059
leukocyte differentiation GO:0002521 342 0.058
macromolecule catabolic process GO:0009057 281 0.058
immune response activating cell surface receptor signaling pathway GO:0002429 72 0.057
multicellular organismal homeostasis GO:0048871 164 0.057
negative regulation of protein modification process GO:0031400 163 0.056
positive regulation of map kinase activity GO:0043406 84 0.055
regulation of kinase activity GO:0043549 249 0.055
positive regulation of immune effector process GO:0002699 107 0.054
organic cyclic compound catabolic process GO:1901361 295 0.052
immune response regulating cell surface receptor signaling pathway GO:0002768 80 0.052
negative regulation of intracellular signal transduction GO:1902532 167 0.052
regulation of reactive oxygen species metabolic process GO:2000377 40 0.051
negative regulation of lymphocyte activation GO:0051250 91 0.051
regulation of t cell proliferation GO:0042129 92 0.050
stress activated mapk cascade GO:0051403 80 0.050
t cell proliferation GO:0042098 120 0.050
heterocycle catabolic process GO:0046700 280 0.050
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.050
regulation of jnk cascade GO:0046328 62 0.049
positive regulation of jun kinase activity GO:0043507 30 0.049
myeloid cell differentiation GO:0030099 233 0.049
regulation of stress activated mapk cascade GO:0032872 69 0.049
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.049
regulation of map kinase activity GO:0043405 120 0.048
homeostasis of number of cells GO:0048872 210 0.048
regulation of lymphocyte proliferation GO:0050670 117 0.047
positive regulation of lymphocyte activation GO:0051251 140 0.047
myeloid leukocyte activation GO:0002274 83 0.047
regulation of cellular amine metabolic process GO:0033238 20 0.047
negative regulation of cell activation GO:0050866 111 0.047
interleukin 6 production GO:0032635 58 0.047
antigen receptor mediated signaling pathway GO:0050851 64 0.046
positive regulation of protein modification process GO:0031401 299 0.046
inflammatory response GO:0006954 244 0.046
protein catabolic process GO:0030163 221 0.046
t cell mediated immunity GO:0002456 50 0.046
purinergic nucleotide receptor signaling pathway GO:0035590 3 0.046
negative regulation of transferase activity GO:0051348 85 0.045
cellular nitrogen compound catabolic process GO:0044270 280 0.045
i kappab kinase nf kappab signaling GO:0007249 85 0.044
protein ubiquitination GO:0016567 171 0.044
nucleoside catabolic process GO:0009164 206 0.043
positive regulation of lipopolysaccharide mediated signaling pathway GO:0031666 5 0.043
leukocyte mediated cytotoxicity GO:0001909 62 0.042
reactive oxygen species metabolic process GO:0072593 84 0.042
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 87 0.042
apoptotic signaling pathway GO:0097190 306 0.041
t cell differentiation GO:0030217 174 0.041
aromatic compound catabolic process GO:0019439 286 0.041
purine ribonucleoside metabolic process GO:0046128 241 0.040
jnk cascade GO:0007254 72 0.039
glycosyl compound catabolic process GO:1901658 206 0.039
cellular lipid metabolic process GO:0044255 323 0.039
cation transport GO:0006812 399 0.039
positive regulation of protein kinase activity GO:0045860 144 0.038
regulation of production of molecular mediator of immune response GO:0002700 65 0.038
regulation of interleukin 12 production GO:0032655 30 0.038
positive regulation of cytokine production GO:0001819 174 0.037
negative regulation of b cell activation GO:0050869 27 0.037
defense response to bacterium GO:0042742 119 0.037
nitrogen compound transport GO:0071705 271 0.037
negative regulation of interleukin 6 production GO:0032715 17 0.037
negative regulation of protein serine threonine kinase activity GO:0071901 49 0.037
cytokine mediated signaling pathway GO:0019221 115 0.036
regulation of lymphocyte differentiation GO:0045619 107 0.036
nucleoside metabolic process GO:0009116 246 0.036
negative regulation of molecular function GO:0044092 258 0.036
regulation of protein catabolic process GO:0042176 108 0.036
membrane organization GO:0061024 245 0.036
lymphocyte proliferation GO:0046651 164 0.036
tumor necrosis factor superfamily cytokine production GO:0071706 51 0.035
leukocyte proliferation GO:0070661 172 0.035
regulation of leukocyte proliferation GO:0070663 121 0.035
organonitrogen compound catabolic process GO:1901565 264 0.035
regulation of protein complex assembly GO:0043254 83 0.035
ribonucleoside triphosphate metabolic process GO:0009199 220 0.035
response to organonitrogen compound GO:0010243 246 0.035
regulation of leukocyte differentiation GO:1902105 159 0.035
cellular ketone metabolic process GO:0042180 84 0.035
response to organic cyclic compound GO:0014070 198 0.035
regulation of jun kinase activity GO:0043506 40 0.034
regulation of t cell activation GO:0050863 170 0.034
ribonucleoside catabolic process GO:0042454 206 0.034
regulation of secretion by cell GO:1903530 249 0.033
nik nf kappab signaling GO:0038061 14 0.033
gtp metabolic process GO:0046039 144 0.033
regulation of cellular catabolic process GO:0031329 242 0.033
positive regulation of protein phosphorylation GO:0001934 242 0.033
positive regulation of cytokine biosynthetic process GO:0042108 40 0.033
immunoglobulin mediated immune response GO:0016064 69 0.033
negative regulation of cellular component organization GO:0051129 194 0.033
t cell activation involved in immune response GO:0002286 43 0.033
nucleobase containing small molecule metabolic process GO:0055086 352 0.033
negative regulation of phosphate metabolic process GO:0045936 184 0.032
negative regulation of cell proliferation GO:0008285 296 0.032
regulation of protein localization GO:0032880 231 0.032
response to dsrna GO:0043331 30 0.032
response to growth factor GO:0070848 198 0.032
glycosyl compound metabolic process GO:1901657 246 0.032
gtp catabolic process GO:0006184 143 0.032
positive regulation of kinase activity GO:0033674 155 0.032
positive regulation of interleukin 12 production GO:0032735 21 0.032
positive regulation of leukocyte proliferation GO:0070665 73 0.031
cytoplasmic transport GO:0016482 234 0.031
cellular response to organonitrogen compound GO:0071417 145 0.031
peptidyl amino acid modification GO:0018193 336 0.031
protein modification by small protein conjugation GO:0032446 187 0.031
posttranscriptional regulation of gene expression GO:0010608 155 0.031
cellular chemical homeostasis GO:0055082 215 0.031
type i interferon production GO:0032606 29 0.031
cellular response to peptidoglycan GO:0071224 4 0.030
erythrocyte differentiation GO:0030218 88 0.030
tissue homeostasis GO:0001894 115 0.030
negative regulation of protein phosphorylation GO:0001933 126 0.030
negative regulation of mapk cascade GO:0043409 65 0.030
peptidyl tyrosine phosphorylation GO:0018108 143 0.030
positive regulation of leukocyte mediated immunity GO:0002705 70 0.030
transmembrane transport GO:0055085 412 0.030
positive regulation of apoptotic process GO:0043065 217 0.030
wound healing GO:0042060 157 0.030
lymphocyte activation involved in immune response GO:0002285 93 0.029
metal ion homeostasis GO:0055065 189 0.029
carbohydrate derivative catabolic process GO:1901136 231 0.029
alpha beta t cell activation GO:0046631 91 0.029
regulation of organelle organization GO:0033043 289 0.029
positive regulation of reactive oxygen species metabolic process GO:2000379 11 0.029
organophosphate catabolic process GO:0046434 232 0.029
regulation of tumor necrosis factor superfamily cytokine production GO:1903555 50 0.028
ribonucleoside metabolic process GO:0009119 245 0.028
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.028
interleukin 12 production GO:0032615 32 0.028
maintenance of location GO:0051235 89 0.028
cell adhesion GO:0007155 329 0.028
purine nucleotide metabolic process GO:0006163 302 0.028
regulation of b cell activation GO:0050864 81 0.027
rho protein signal transduction GO:0007266 32 0.027
positive regulation of programmed cell death GO:0043068 218 0.027
skin development GO:0043588 220 0.027
protein polyubiquitination GO:0000209 33 0.027
regulation of response to biotic stimulus GO:0002831 38 0.026
positive regulation of lymphocyte mediated immunity GO:0002708 62 0.026
toll like receptor 2 signaling pathway GO:0034134 6 0.026
ribose phosphate metabolic process GO:0019693 291 0.026
regulation of defense response to bacterium GO:1900424 3 0.026
regulation of cell cycle GO:0051726 281 0.026
negative regulation of innate immune response GO:0045824 17 0.026
purine containing compound catabolic process GO:0072523 213 0.026
cytokine metabolic process GO:0042107 71 0.026
positive regulation of cell death GO:0010942 224 0.025
regulation of tumor necrosis factor production GO:0032680 49 0.025
lysosome localization GO:0032418 20 0.025
anatomical structure homeostasis GO:0060249 145 0.025
regulation of cell motility GO:2000145 236 0.025
nucleoside phosphate metabolic process GO:0006753 338 0.025
purine nucleoside triphosphate metabolic process GO:0009144 226 0.025
small molecule biosynthetic process GO:0044283 132 0.025
gland development GO:0048732 330 0.025
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 61 0.024
small gtpase mediated signal transduction GO:0007264 97 0.024
b cell mediated immunity GO:0019724 71 0.024
epithelial cell proliferation GO:0050673 174 0.024
positive regulation of adaptive immune response GO:0002821 61 0.024
sequestering of metal ion GO:0051238 19 0.024
ion transmembrane transport GO:0034220 361 0.024
regulation of ion transport GO:0043269 215 0.024
hematopoietic progenitor cell differentiation GO:0002244 143 0.024
regulation of membrane potential GO:0042391 192 0.024
regulation of secretion GO:0051046 274 0.024
nucleoside triphosphate metabolic process GO:0009141 230 0.024
cellular protein catabolic process GO:0044257 155 0.023
regulation of wnt signaling pathway GO:0030111 123 0.023
male gamete generation GO:0048232 285 0.023
regulation of protein secretion GO:0050708 82 0.023
hemostasis GO:0007599 78 0.023
regulation of protein transport GO:0051223 163 0.023
purine ribonucleotide metabolic process GO:0009150 290 0.023
regulation of cellular component biogenesis GO:0044087 181 0.023
regulation of t cell differentiation GO:0045580 83 0.023
purine ribonucleoside catabolic process GO:0046130 205 0.023
autophagy GO:0006914 45 0.023
ribonucleotide catabolic process GO:0009261 208 0.022
dna metabolic process GO:0006259 303 0.022
nucleoside phosphate catabolic process GO:1901292 222 0.022
cellular homeostasis GO:0019725 240 0.022
immunoglobulin production GO:0002377 73 0.022
lipid biosynthetic process GO:0008610 179 0.022
regulation of mast cell activation involved in immune response GO:0033006 17 0.022
endocytosis GO:0006897 168 0.022
regulation of apoptotic signaling pathway GO:2001233 197 0.022
toll like receptor 7 signaling pathway GO:0034154 4 0.022
leukocyte apoptotic process GO:0071887 71 0.022
glycerolipid metabolic process GO:0046486 122 0.022
cellular metal ion homeostasis GO:0006875 151 0.022
regulation of establishment of protein localization GO:0070201 181 0.022
cytokine biosynthetic process GO:0042089 68 0.022
negative regulation of lymphocyte proliferation GO:0050672 45 0.022
ribonucleoside triphosphate catabolic process GO:0009203 199 0.022
tumor necrosis factor production GO:0032640 50 0.022
angiogenesis GO:0001525 201 0.022
regulation of adaptive immune response GO:0002819 90 0.022
purine nucleotide catabolic process GO:0006195 211 0.021
positive regulation of t cell activation GO:0050870 101 0.021
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 68 0.021
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.021
positive regulation of cytokine production involved in immune response GO:0002720 19 0.021
negative regulation of map kinase activity GO:0043407 34 0.021
cellular response to dna damage stimulus GO:0006974 207 0.021
positive regulation of secretion by cell GO:1903532 114 0.021
positive regulation of organelle organization GO:0010638 128 0.021
mitochondrion organization GO:0007005 134 0.021
organonitrogen compound biosynthetic process GO:1901566 192 0.021
regulation of cell adhesion GO:0030155 154 0.020
cellular macromolecule catabolic process GO:0044265 206 0.020
nucleotide metabolic process GO:0009117 332 0.020
regulation of myeloid leukocyte differentiation GO:0002761 58 0.020
regulation of alpha beta t cell activation GO:0046634 53 0.020
negative regulation of sterol transport GO:0032372 4 0.020
regulation of homeostatic process GO:0032844 182 0.020
cell substrate adhesion GO:0031589 130 0.020
organic anion transport GO:0015711 137 0.020
regulation of vesicle mediated transport GO:0060627 139 0.020
regulation of hormone levels GO:0010817 211 0.020
regulation of myeloid cell differentiation GO:0045637 96 0.020
leukocyte migration GO:0050900 124 0.020
lymphocyte differentiation GO:0030098 242 0.020
negative regulation of phosphorus metabolic process GO:0010563 184 0.020
negative regulation of cholesterol transport GO:0032375 4 0.020
morphogenesis of embryonic epithelium GO:0016331 159 0.020
epidermis development GO:0008544 187 0.020
wnt signaling pathway GO:0016055 188 0.019
cation transmembrane transport GO:0098655 266 0.019
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.019
hormone secretion GO:0046879 128 0.019
purine nucleoside metabolic process GO:0042278 241 0.019
purine nucleoside catabolic process GO:0006152 205 0.019
protein localization to organelle GO:0033365 185 0.019
action potential GO:0001508 78 0.019
regulation of t cell mediated immunity GO:0002709 34 0.019
regulation of lymphocyte mediated immunity GO:0002706 84 0.019
extrinsic apoptotic signaling pathway GO:0097191 126 0.019
purine containing compound metabolic process GO:0072521 311 0.019
carbohydrate derivative biosynthetic process GO:1901137 183 0.019
lymphocyte apoptotic process GO:0070227 54 0.019
lymphocyte homeostasis GO:0002260 64 0.019
regulation of leukocyte apoptotic process GO:2000106 56 0.019
divalent inorganic cation transport GO:0072511 178 0.019
interspecies interaction between organisms GO:0044419 83 0.019
erk1 and erk2 cascade GO:0070371 77 0.019
tube formation GO:0035148 140 0.019
negative regulation of t cell proliferation GO:0042130 38 0.018
skeletal system development GO:0001501 356 0.018
antigen processing and presentation of peptide or polysaccharide antigen via mhc class ii GO:0002504 17 0.018
cellular response to growth factor stimulus GO:0071363 197 0.018
protein complex disassembly GO:0043241 40 0.018
calcium ion transport GO:0006816 159 0.018
negative regulation of nervous system development GO:0051961 156 0.018
positive regulation of t cell mediated immunity GO:0002711 24 0.018
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.018
neuronal action potential GO:0019228 54 0.018
rhythmic process GO:0048511 174 0.018
phospholipid metabolic process GO:0006644 87 0.018
spermatogenesis GO:0007283 284 0.018
transmission of nerve impulse GO:0019226 76 0.018
defense response to virus GO:0051607 68 0.018
regulation of lipid transport GO:0032368 36 0.018
myeloid cell homeostasis GO:0002262 114 0.018
positive regulation of cellular component biogenesis GO:0044089 94 0.018
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 40 0.018
cellular ion homeostasis GO:0006873 165 0.017
lateral inhibition GO:0046331 1 0.017
monocarboxylic acid metabolic process GO:0032787 191 0.017
leukocyte chemotaxis GO:0030595 69 0.017
actin filament organization GO:0007015 113 0.017
negative regulation of nf kappab transcription factor activity GO:0032088 15 0.017
regulation of nik nf kappab signaling GO:1901222 10 0.017
cellular response to hormone stimulus GO:0032870 150 0.017
peptidyl tyrosine modification GO:0018212 145 0.017
regulation of cell migration GO:0030334 219 0.017
cellularization GO:0007349 1 0.017
amide transport GO:0042886 138 0.017
regulation of binding GO:0051098 111 0.017
negative regulation of phosphorylation GO:0042326 166 0.017
sequestering of calcium ion GO:0051208 18 0.017
interferon beta production GO:0032608 16 0.017
positive regulation of production of molecular mediator of immune response GO:0002702 45 0.017
neuron death GO:0070997 154 0.017
actin cytoskeleton organization GO:0030036 220 0.017
cellular calcium ion homeostasis GO:0006874 119 0.017
inorganic cation transmembrane transport GO:0098662 207 0.017
ras protein signal transduction GO:0007265 77 0.017
intrinsic apoptotic signaling pathway GO:0097193 132 0.017
cellular divalent inorganic cation homeostasis GO:0072503 127 0.016
regulation of intracellular transport GO:0032386 159 0.016
negative regulation of cellular amine metabolic process GO:0033239 1 0.016
embryonic epithelial tube formation GO:0001838 130 0.016
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.016
response to peptidoglycan GO:0032494 9 0.016
covalent chromatin modification GO:0016569 163 0.016
g protein coupled receptor signaling pathway GO:0007186 243 0.016
regulation of type i interferon production GO:0032479 22 0.016
regulation of antimicrobial humoral response GO:0002759 3 0.016
regulation of antimicrobial peptide biosynthetic process GO:0002805 1 0.016
positive regulation of cell adhesion GO:0045785 80 0.016
canonical wnt signaling pathway GO:0060070 130 0.016
guanosine containing compound metabolic process GO:1901068 144 0.016
cellular protein complex assembly GO:0043623 116 0.016
negative regulation of cellular protein metabolic process GO:0032269 247 0.016
positive regulation of b cell activation GO:0050871 49 0.016
regulation of lipid metabolic process GO:0019216 118 0.016
negative regulation of multi organism process GO:0043901 68 0.016
neural tube formation GO:0001841 108 0.016
positive regulation of antimicrobial humoral response GO:0002760 2 0.016
organophosphate biosynthetic process GO:0090407 122 0.016
organic acid transport GO:0015849 101 0.016
regulation of interleukin 10 secretion GO:2001179 4 0.016
regulation of endocytosis GO:0030100 69 0.016
histone modification GO:0016570 159 0.016
alcohol metabolic process GO:0006066 116 0.016
positive regulation of hydrolase activity GO:0051345 148 0.016
monocarboxylic acid biosynthetic process GO:0072330 61 0.015
anion transport GO:0006820 177 0.015
response to oxidative stress GO:0006979 123 0.015
protein secretion GO:0009306 111 0.015
purine ribonucleotide catabolic process GO:0009154 208 0.015
reactive oxygen species biosynthetic process GO:1903409 8 0.015
b cell proliferation GO:0042100 53 0.015
chemotaxis GO:0006935 247 0.015
protein autophosphorylation GO:0046777 61 0.015
protein oligomerization GO:0051259 67 0.015
learning or memory GO:0007611 148 0.015
extracellular structure organization GO:0043062 148 0.015
purine nucleoside triphosphate catabolic process GO:0009146 203 0.015
olfactory learning GO:0008355 2 0.015
positive regulation of protein complex assembly GO:0031334 45 0.015
b cell activation involved in immune response GO:0002312 50 0.015
positive regulation of leukocyte differentiation GO:1902107 86 0.015
negative regulation of t cell activation GO:0050868 65 0.015
fatty acid metabolic process GO:0006631 121 0.015
methylation GO:0032259 134 0.015
guanosine containing compound catabolic process GO:1901069 144 0.015
myeloid leukocyte differentiation GO:0002573 119 0.015
negative regulation of growth GO:0045926 99 0.015
response to interferon gamma GO:0034341 34 0.015
organelle localization GO:0051640 179 0.015
regulation of leukocyte mediated cytotoxicity GO:0001910 38 0.015
ribonucleotide metabolic process GO:0009259 291 0.015
negative regulation of ripoptosome assembly involved in necroptotic process GO:1902443 3 0.015
divalent metal ion transport GO:0070838 172 0.014
ossification GO:0001503 216 0.014
exocytosis GO:0006887 121 0.014
respiratory tube development GO:0030323 167 0.014
nucleotide catabolic process GO:0009166 217 0.014
urogenital system development GO:0001655 261 0.014
regulation of body fluid levels GO:0050878 162 0.014
cellular response to oxidative stress GO:0034599 76 0.014
cell killing GO:0001906 67 0.014
positive regulation of nucleotide catabolic process GO:0030813 88 0.014
organic hydroxy compound metabolic process GO:1901615 203 0.014
phagocytosis GO:0006909 66 0.014
cognition GO:0050890 149 0.014
positive regulation of nf kappab transcription factor activity GO:0051092 30 0.014
regulation of response to wounding GO:1903034 189 0.014
regulation of neuron differentiation GO:0045664 281 0.014
negative regulation of b cell proliferation GO:0030889 13 0.014
fat cell differentiation GO:0045444 160 0.014
epithelial tube formation GO:0072175 130 0.014
compound eye development GO:0048749 1 0.014
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.014
reactive nitrogen species metabolic process GO:2001057 0 0.014
intracellular receptor signaling pathway GO:0030522 74 0.014
regulation of multi organism process GO:0043900 111 0.014
organic acid biosynthetic process GO:0016053 86 0.014
regulation of immunoglobulin production GO:0002637 42 0.014
organelle assembly GO:0070925 177 0.014
regulation of actin cytoskeleton organization GO:0032956 84 0.014
positive regulation of response to wounding GO:1903036 66 0.014
chromatin organization GO:0006325 206 0.014
leukocyte homeostasis GO:0001776 79 0.014
regulation of interferon beta biosynthetic process GO:0045357 4 0.013
sensory perception GO:0007600 245 0.013
amino acid transport GO:0006865 61 0.013
positive regulation of cell motility GO:2000147 116 0.013
regulation of transmembrane transport GO:0034762 128 0.013
mast cell mediated immunity GO:0002448 20 0.013
positive regulation of secretion GO:0051047 130 0.013
regulation of actin polymerization or depolymerization GO:0008064 45 0.013
regulation of cellular component size GO:0032535 121 0.013
divalent inorganic cation homeostasis GO:0072507 138 0.013
positive regulation of interleukin 1 alpha production GO:0032730 4 0.013
protein localization to nucleus GO:0034504 121 0.013
alpha beta t cell differentiation GO:0046632 69 0.013
regulation of blood coagulation GO:0030193 28 0.013
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.013
midgut development GO:0007494 4 0.013
ubiquitin dependent protein catabolic process GO:0006511 129 0.013
regulation of cytokine biosynthetic process GO:0042035 59 0.013
negative regulation of tumor necrosis factor superfamily cytokine production GO:1903556 17 0.013
lung development GO:0030324 164 0.013
antimicrobial peptide production GO:0002775 2 0.013
myeloid leukocyte mediated immunity GO:0002444 42 0.013
muscle tissue development GO:0060537 308 0.013
alcohol biosynthetic process GO:0046165 43 0.013
negative regulation of tumor necrosis factor production GO:0032720 17 0.013
defense response to gram positive bacterium GO:0050830 50 0.012
regulation of dna binding GO:0051101 39 0.012
myd88 independent toll like receptor signaling pathway GO:0002756 3 0.012
regulation of chemokine production GO:0032642 30 0.012
myeloid leukocyte cytokine production GO:0061082 12 0.012
response to radiation GO:0009314 165 0.012
peptidyl lysine modification GO:0018205 77 0.012
digestive system development GO:0055123 200 0.012
t cell receptor signaling pathway GO:0050852 46 0.012
glycoprotein metabolic process GO:0009100 116 0.012
tolerance induction to self antigen GO:0002513 4 0.012
antimicrobial peptide biosynthetic process GO:0002777 2 0.012
antigen processing and presentation of peptide antigen GO:0048002 29 0.012
positive regulation of homeostatic process GO:0032846 64 0.012

Tifa disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.050
musculoskeletal system disease DOID:17 0 0.050
connective tissue disease DOID:65 0 0.050
nervous system disease DOID:863 0 0.026
disease of metabolism DOID:0014667 0 0.019
cancer DOID:162 0 0.016
disease of cellular proliferation DOID:14566 0 0.016
organ system cancer DOID:0050686 0 0.016