Mus musculus

34 known processes

Spock3

sparc/osteonectin, cwcv and kazal-like domains proteoglycan 3

(Aliases: mKIAA4039,KIAA4039,AI428471,2900045C01Rik)

Spock3 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cell adhesion GO:0007155 329 0.082
Mouse
cellular amino acid metabolic process GO:0006520 103 0.074
ion transmembrane transport GO:0034220 361 0.064
cellular ketone metabolic process GO:0042180 84 0.060
regulation of cellular amino acid metabolic process GO:0006521 5 0.058
amine metabolic process GO:0009308 45 0.057
transmembrane transport GO:0055085 412 0.054
regulation of membrane potential GO:0042391 192 0.052
cellular lipid metabolic process GO:0044255 323 0.050
synaptic transmission GO:0007268 329 0.048
cellular amine metabolic process GO:0044106 44 0.048
regulation of cellular amine metabolic process GO:0033238 20 0.048
regulation of cellular ketone metabolic process GO:0010565 66 0.045
cation transmembrane transport GO:0098655 266 0.044
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.042
apoptotic signaling pathway GO:0097190 306 0.040
regulation of proteolysis GO:0030162 164 0.039
Human
positive regulation of protein modification process GO:0031401 299 0.038
locomotory behavior GO:0007626 195 0.037
muscle cell differentiation GO:0042692 261 0.036
mapk cascade GO:0000165 281 0.036
oxidation reduction process GO:0055114 342 0.036
g protein coupled receptor signaling pathway GO:0007186 243 0.035
anion transport GO:0006820 177 0.034
cation transport GO:0006812 399 0.033
positive regulation of protein phosphorylation GO:0001934 242 0.033
positive regulation of cellular amine metabolic process GO:0033240 5 0.033
membrane organization GO:0061024 245 0.032
regulation of hormone levels GO:0010817 211 0.032
gland development GO:0048732 330 0.032
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.030
regulation of hydrolase activity GO:0051336 246 0.029
Human
response to organonitrogen compound GO:0010243 246 0.029
urogenital system development GO:0001655 261 0.028
small gtpase mediated signal transduction GO:0007264 97 0.028
nitrogen compound transport GO:0071705 271 0.028
action potential GO:0001508 78 0.028
ras protein signal transduction GO:0007265 77 0.028
regulation of cellular component biogenesis GO:0044087 181 0.027
regulation of protein kinase activity GO:0045859 232 0.027
male gamete generation GO:0048232 285 0.026
forebrain development GO:0030900 302 0.026
response to organic cyclic compound GO:0014070 198 0.025
spermatogenesis GO:0007283 284 0.025
regulation of cytokine production GO:0001817 266 0.025
anatomical structure homeostasis GO:0060249 145 0.025
organic hydroxy compound metabolic process GO:1901615 203 0.024
positive regulation of transferase activity GO:0051347 167 0.024
striated muscle tissue development GO:0014706 293 0.023
neuron neuron synaptic transmission GO:0007270 69 0.023
lipid biosynthetic process GO:0008610 179 0.023
regulation of secretion GO:0051046 274 0.023
fatty acid metabolic process GO:0006631 121 0.023
positive regulation of programmed cell death GO:0043068 218 0.023
negative regulation of intracellular signal transduction GO:1902532 167 0.023
cell type specific apoptotic process GO:0097285 268 0.023
cytokine production GO:0001816 319 0.023
organic anion transport GO:0015711 137 0.023
multicellular organismal homeostasis GO:0048871 164 0.023
monocarboxylic acid metabolic process GO:0032787 191 0.023
regulation of mapk cascade GO:0043408 248 0.023
regulation of transferase activity GO:0051338 263 0.022
nucleobase containing small molecule metabolic process GO:0055086 352 0.022
muscle tissue development GO:0060537 308 0.022
cellular protein complex assembly GO:0043623 116 0.022
nucleoside phosphate metabolic process GO:0006753 338 0.022
positive regulation of nervous system development GO:0051962 221 0.022
anion transmembrane transport GO:0098656 71 0.022
macromolecule catabolic process GO:0009057 281 0.022
protein modification by small protein conjugation or removal GO:0070647 207 0.022
organonitrogen compound catabolic process GO:1901565 264 0.021
renal system development GO:0072001 225 0.021
protein localization to organelle GO:0033365 185 0.021
learning or memory GO:0007611 148 0.021
response to radiation GO:0009314 165 0.021
multicellular organismal signaling GO:0035637 91 0.021
carbohydrate metabolic process GO:0005975 230 0.021
regulation of organelle organization GO:0033043 289 0.021
cellular response to lipid GO:0071396 145 0.021
nucleotide metabolic process GO:0009117 332 0.021
hematopoietic progenitor cell differentiation GO:0002244 143 0.021
protein catabolic process GO:0030163 221 0.020
regulation of peptidase activity GO:0052547 96 0.020
Human
cognition GO:0050890 149 0.020
purine nucleotide metabolic process GO:0006163 302 0.020
positive regulation of cell death GO:0010942 224 0.020
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.020
regulation of cellular response to stress GO:0080135 159 0.020
aromatic compound catabolic process GO:0019439 286 0.020
regulation of cell adhesion GO:0030155 154 0.020
Mouse
negative regulation of protein metabolic process GO:0051248 282 0.020
Human
camera type eye development GO:0043010 266 0.019
negative regulation of molecular function GO:0044092 258 0.019
Human
leukocyte differentiation GO:0002521 342 0.019
regulation of cell projection organization GO:0031344 206 0.019
transmission of nerve impulse GO:0019226 76 0.019
negative regulation of cellular component organization GO:0051129 194 0.019
regulation of system process GO:0044057 200 0.019
regulation of lymphocyte activation GO:0051249 240 0.019
protein modification by small protein conjugation GO:0032446 187 0.019
regulation of cellular catabolic process GO:0031329 242 0.019
inorganic ion transmembrane transport GO:0098660 234 0.019
cellular response to organonitrogen compound GO:0071417 145 0.019
negative regulation of phosphorus metabolic process GO:0010563 184 0.019
intracellular protein transport GO:0006886 204 0.019
multicellular organism growth GO:0035264 161 0.018
t cell activation GO:0042110 289 0.018
response to molecule of bacterial origin GO:0002237 143 0.018
positive regulation of cell development GO:0010720 237 0.018
regulation of cell activation GO:0050865 289 0.018
purine ribonucleotide metabolic process GO:0009150 290 0.018
negative regulation of phosphate metabolic process GO:0045936 184 0.018
regulation of protein serine threonine kinase activity GO:0071900 157 0.018
protein processing GO:0016485 163 0.018
Human
positive regulation of secretion by cell GO:1903532 114 0.018
kidney development GO:0001822 213 0.018
regulation of feeding behavior GO:0060259 3 0.018
regulation of secretion by cell GO:1903530 249 0.018
ear development GO:0043583 200 0.018
cytoplasmic transport GO:0016482 234 0.018
immune effector process GO:0002252 321 0.017
peptidyl amino acid modification GO:0018193 336 0.017
response to peptide hormone GO:0043434 127 0.017
ribonucleotide metabolic process GO:0009259 291 0.017
posttranscriptional regulation of gene expression GO:0010608 155 0.017
carbohydrate derivative biosynthetic process GO:1901137 183 0.017
extracellular matrix organization GO:0030198 147 0.017
Mouse
regulation of nucleotide metabolic process GO:0006140 169 0.017
cellular homeostasis GO:0019725 240 0.017
positive regulation of secretion GO:0051047 130 0.017
positive regulation of cell projection organization GO:0031346 95 0.017
regulation of neuron differentiation GO:0045664 281 0.017
adult behavior GO:0030534 135 0.017
dna metabolic process GO:0006259 303 0.017
response to growth factor GO:0070848 198 0.017
negative regulation of phosphorylation GO:0042326 166 0.017
sensory perception GO:0007600 245 0.017
cellular response to hormone stimulus GO:0032870 150 0.017
circulatory system process GO:0003013 197 0.017
angiogenesis GO:0001525 201 0.017
inorganic cation transmembrane transport GO:0098662 207 0.017
regulation of kinase activity GO:0043549 249 0.017
single organism cell adhesion GO:0098602 156 0.017
respiratory system development GO:0060541 190 0.017
negative regulation of cell proliferation GO:0008285 296 0.017
reactive oxygen species metabolic process GO:0072593 84 0.016
ribonucleoside metabolic process GO:0009119 245 0.016
tissue homeostasis GO:0001894 115 0.016
regulation of defense response GO:0031347 233 0.016
maintenance of location GO:0051235 89 0.016
response to acid chemical GO:0001101 111 0.016
myotube differentiation GO:0014902 105 0.016
positive regulation of neuron differentiation GO:0045666 141 0.016
regulation of cell motility GO:2000145 236 0.016
glycoprotein metabolic process GO:0009100 116 0.016
regulation of apoptotic signaling pathway GO:2001233 197 0.016
positive regulation of cell activation GO:0050867 158 0.016
negative regulation of cellular protein metabolic process GO:0032269 247 0.016
Human
extracellular structure organization GO:0043062 148 0.016
Mouse
innate immune response GO:0045087 157 0.016
endocytosis GO:0006897 168 0.016
negative regulation of cell development GO:0010721 169 0.016
rho protein signal transduction GO:0007266 32 0.016
response to nutrient levels GO:0031667 109 0.016
positive regulation of mapk cascade GO:0043410 170 0.016
chemotaxis GO:0006935 247 0.016
response to lipopolysaccharide GO:0032496 128 0.015
regulation of neuron apoptotic process GO:0043523 122 0.015
lymphocyte differentiation GO:0030098 242 0.015
cation homeostasis GO:0055080 212 0.015
neuron death GO:0070997 154 0.015
organic cyclic compound catabolic process GO:1901361 295 0.015
protein localization to membrane GO:0072657 108 0.015
epithelial tube morphogenesis GO:0060562 303 0.015
protein ubiquitination GO:0016567 171 0.015
cellular nitrogen compound catabolic process GO:0044270 280 0.015
microtubule based process GO:0007017 236 0.015
negative regulation of cellular amine metabolic process GO:0033239 1 0.015
single organismal cell cell adhesion GO:0016337 131 0.015
regulation of purine nucleotide metabolic process GO:1900542 169 0.015
regulation of cell cycle GO:0051726 281 0.015
cellular response to growth factor stimulus GO:0071363 197 0.015
regulation of anatomical structure size GO:0090066 178 0.015
ribose phosphate metabolic process GO:0019693 291 0.015
generation of precursor metabolites and energy GO:0006091 103 0.015
negative regulation of protein modification process GO:0031400 163 0.015
muscle cell development GO:0055001 133 0.015
regulation of reactive oxygen species metabolic process GO:2000377 40 0.015
nucleoside triphosphate metabolic process GO:0009141 230 0.015
purine nucleotide catabolic process GO:0006195 211 0.015
regulation of cell migration GO:0030334 219 0.015
cellular chemical homeostasis GO:0055082 215 0.015
regulation of protein maturation GO:1903317 96 0.015
Human
glycosyl compound metabolic process GO:1901657 246 0.015
organonitrogen compound biosynthetic process GO:1901566 192 0.014
organic hydroxy compound transport GO:0015850 93 0.014
cellular response to organic cyclic compound GO:0071407 87 0.014
regulation of protein transport GO:0051223 163 0.014
protein maturation GO:0051604 176 0.014
Human
telencephalon development GO:0021537 186 0.014
cell substrate adhesion GO:0031589 130 0.014
Mouse
nucleoside metabolic process GO:0009116 246 0.014
small molecule biosynthetic process GO:0044283 132 0.014
positive regulation of kinase activity GO:0033674 155 0.014
sulfur compound metabolic process GO:0006790 100 0.014
nucleotide catabolic process GO:0009166 217 0.014
positive regulation of cytokine production GO:0001819 174 0.014
regulation of protein catabolic process GO:0042176 108 0.014
cellular response to dna damage stimulus GO:0006974 207 0.014
leukocyte migration GO:0050900 124 0.014
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.014
morphogenesis of a branching structure GO:0001763 203 0.014
heterocycle catabolic process GO:0046700 280 0.014
cell growth GO:0016049 130 0.014
synapse organization GO:0050808 125 0.014
regulation of establishment of protein localization GO:0070201 181 0.014
carbohydrate derivative catabolic process GO:1901136 231 0.014
ribonucleoside triphosphate metabolic process GO:0009199 220 0.014
positive regulation of cell adhesion GO:0045785 80 0.014
Mouse
placenta development GO:0001890 140 0.014
purine nucleoside metabolic process GO:0042278 241 0.014
negative regulation of protein processing GO:0010955 79 0.014
Human
regulation of neuron projection development GO:0010975 169 0.014
blood vessel morphogenesis GO:0048514 285 0.014
lung development GO:0030324 164 0.014
carboxylic acid transport GO:0046942 100 0.014
purine ribonucleotide catabolic process GO:0009154 208 0.014
multi multicellular organism process GO:0044706 109 0.014
positive regulation of apoptotic process GO:0043065 217 0.014
regulation of protein processing GO:0070613 96 0.014
Human
regulation of response to wounding GO:1903034 189 0.014
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.014
regulation of endopeptidase activity GO:0052548 89 0.014
Human
axonogenesis GO:0007409 274 0.014
positive regulation of lymphocyte activation GO:0051251 140 0.014
protein targeting GO:0006605 143 0.014
developmental growth involved in morphogenesis GO:0060560 138 0.014
purine ribonucleoside metabolic process GO:0046128 241 0.013
purine containing compound metabolic process GO:0072521 311 0.013
positive regulation of cellular component biogenesis GO:0044089 94 0.013
embryonic organ morphogenesis GO:0048562 276 0.013
cellular ion homeostasis GO:0006873 165 0.013
organophosphate biosynthetic process GO:0090407 122 0.013
regulation of protein localization GO:0032880 231 0.013
carbohydrate homeostasis GO:0033500 128 0.013
regulation of cellular component size GO:0032535 121 0.013
positive regulation of protein kinase activity GO:0045860 144 0.013
response to extracellular stimulus GO:0009991 127 0.013
learning GO:0007612 98 0.013
norepinephrine transport GO:0015874 2 0.013
response to peptide GO:1901652 136 0.013
cellular response to biotic stimulus GO:0071216 92 0.013
skin development GO:0043588 220 0.013
steroid metabolic process GO:0008202 119 0.013
organelle localization GO:0051640 179 0.013
inflammatory response GO:0006954 244 0.013
heart process GO:0003015 94 0.013
cellular macromolecule catabolic process GO:0044265 206 0.013
muscle system process GO:0003012 141 0.013
energy derivation by oxidation of organic compounds GO:0015980 77 0.013
myeloid cell differentiation GO:0030099 233 0.013
actin filament organization GO:0007015 113 0.013
protein secretion GO:0009306 111 0.013
sensory organ morphogenesis GO:0090596 242 0.013
hormone metabolic process GO:0042445 86 0.012
bone development GO:0060348 120 0.012
reactive nitrogen species metabolic process GO:2001057 0 0.012
skeletal muscle organ development GO:0060538 163 0.012
metal ion homeostasis GO:0055065 189 0.012
reactive oxygen species biosynthetic process GO:1903409 8 0.012
purine nucleoside catabolic process GO:0006152 205 0.012
peptidyl tyrosine phosphorylation GO:0018108 143 0.012
branching morphogenesis of an epithelial tube GO:0048754 159 0.012
alcohol metabolic process GO:0006066 116 0.012
blood circulation GO:0008015 195 0.012
rhythmic process GO:0048511 174 0.012
striated muscle cell development GO:0055002 125 0.012
regulation of map kinase activity GO:0043405 120 0.012
skeletal system development GO:0001501 356 0.012
spermatid differentiation GO:0048515 115 0.012
organic acid transport GO:0015849 101 0.012
regulation of protein complex assembly GO:0043254 83 0.012
endomembrane system organization GO:0010256 147 0.012
regulation of homeostatic process GO:0032844 182 0.012
morphogenesis of a branching epithelium GO:0061138 193 0.012
lipid localization GO:0010876 126 0.012
cellular response to cytokine stimulus GO:0071345 189 0.012
ribonucleotide catabolic process GO:0009261 208 0.012
protein localization to nucleus GO:0034504 121 0.012
connective tissue development GO:0061448 179 0.012
positive regulation of proteolysis GO:0045862 85 0.012
cellular carbohydrate metabolic process GO:0044262 119 0.012
exocytosis GO:0006887 121 0.012
fat cell differentiation GO:0045444 160 0.012
lipid catabolic process GO:0016042 69 0.012
ribonucleoside catabolic process GO:0042454 206 0.012
glycoprotein biosynthetic process GO:0009101 89 0.012
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.012
protein polymerization GO:0051258 57 0.012
peptidyl tyrosine modification GO:0018212 145 0.012
organophosphate catabolic process GO:0046434 232 0.012
respiratory tube development GO:0030323 167 0.012
negative regulation of immune system process GO:0002683 209 0.012
negative regulation of neuron death GO:1901215 98 0.011
purine ribonucleoside catabolic process GO:0046130 205 0.011
mitotic cytokinesis GO:0000281 4 0.011
regionalization GO:0003002 337 0.011
neuron apoptotic process GO:0051402 142 0.011
nucleoside catabolic process GO:0009164 206 0.011
negative regulation of growth GO:0045926 99 0.011
leukocyte proliferation GO:0070661 172 0.011
purine containing compound catabolic process GO:0072523 213 0.011
digestive tract development GO:0048565 190 0.011
digestive system development GO:0055123 200 0.011
muscle fiber development GO:0048747 76 0.011
negative regulation of nervous system development GO:0051961 156 0.011
regulation of vasculature development GO:1901342 88 0.011
b cell activation GO:0042113 161 0.011
regulation of purine nucleotide catabolic process GO:0033121 122 0.011
skeletal system morphogenesis GO:0048705 203 0.011
inter male aggressive behavior GO:0002121 3 0.011
epithelial cell development GO:0002064 159 0.011
methylation GO:0032259 134 0.011
regulation of cell growth GO:0001558 91 0.011
leukocyte mediated immunity GO:0002443 174 0.011
lipid transport GO:0006869 98 0.011
mitotic cell cycle GO:0000278 195 0.011
spermatid development GO:0007286 108 0.011
erk1 and erk2 cascade GO:0070371 77 0.011
cellular protein catabolic process GO:0044257 155 0.011
lymphocyte proliferation GO:0046651 164 0.011
protein oligomerization GO:0051259 67 0.011
intrinsic apoptotic signaling pathway GO:0097193 132 0.011
nucleoside phosphate catabolic process GO:1901292 222 0.011
positive regulation of growth GO:0045927 104 0.011
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 61 0.011
peptide secretion GO:0002790 114 0.011
positive regulation of cell migration GO:0030335 109 0.011
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.011
negative regulation of protein phosphorylation GO:0001933 126 0.011
microtubule cytoskeleton organization GO:0000226 157 0.011
organic acid biosynthetic process GO:0016053 86 0.011
response to transforming growth factor beta GO:0071559 88 0.011
cell maturation GO:0048469 127 0.011
response to inorganic substance GO:0010035 96 0.011
divalent inorganic cation transport GO:0072511 178 0.011
purine nucleoside triphosphate catabolic process GO:0009146 203 0.011
regulation of leukocyte differentiation GO:1902105 159 0.011
mesodermal cell migration GO:0008078 4 0.010
purine nucleoside triphosphate metabolic process GO:0009144 226 0.010
palate development GO:0060021 76 0.010
cytokine secretion GO:0050663 72 0.010
sodium ion transmembrane transport GO:0035725 49 0.010
chloride transmembrane transport GO:1902476 24 0.010
plasma membrane organization GO:0007009 90 0.010
negative regulation of neuron apoptotic process GO:0043524 92 0.010
negative regulation of cell motility GO:2000146 61 0.010
compound eye development GO:0048749 1 0.010
regulation of interleukin 10 secretion GO:2001179 4 0.010
glycosylation GO:0070085 62 0.010
homeostasis of number of cells GO:0048872 210 0.010
epidermis development GO:0008544 187 0.010
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.010
regulation of body fluid levels GO:0050878 162 0.010
regulation of response to drug GO:2001023 2 0.010
amide transport GO:0042886 138 0.010
development of primary sexual characteristics GO:0045137 143 0.010
peptidyl serine modification GO:0018209 83 0.010
nucleocytoplasmic transport GO:0006913 139 0.010
regulation of cytoskeleton organization GO:0051493 122 0.010
chloride transport GO:0006821 32 0.010
cellular calcium ion homeostasis GO:0006874 119 0.010
fertilization GO:0009566 127 0.010
protein import GO:0017038 101 0.010

Spock3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.032
nervous system disease DOID:863 0 0.032
musculoskeletal system disease DOID:17 0 0.013
sensory system disease DOID:0050155 0 0.012
central nervous system disease DOID:331 0 0.011
disease of mental health DOID:150 0 0.011
connective tissue disease DOID:65 0 0.011