Mus musculus

118 known processes

Pdgfa

platelet derived growth factor, alpha

Pdgfa biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
response to growth factor GO:0070848 198 0.443
Mouse
peptidyl amino acid modification GO:0018193 336 0.436
cellular amine metabolic process GO:0044106 44 0.396
negative regulation of cell proliferation GO:0008285 296 0.298
Mouse
epithelial tube morphogenesis GO:0060562 303 0.275
Mouse Fly
cellular amino acid metabolic process GO:0006520 103 0.275
regulation of cell motility GO:2000145 236 0.264
Human Mouse
activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 3 0.252
positive regulation of protein kinase activity GO:0045860 144 0.249
Human
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.247
positive regulation of cell migration GO:0030335 109 0.247
Human Mouse
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.233
Human Mouse
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.228
Mouse
response to radiation GO:0009314 165 0.226
Fly
cellular response to amino acid stimulus GO:0071230 29 0.225
blood vessel morphogenesis GO:0048514 285 0.218
skeletal system development GO:0001501 356 0.216
embryonic organ morphogenesis GO:0048562 276 0.213
regulation of bmp signaling pathway GO:0030510 60 0.213
striated muscle tissue development GO:0014706 293 0.211
Mouse
cellular response to growth factor stimulus GO:0071363 197 0.211
Mouse
regulation of apoptotic signaling pathway GO:2001233 197 0.211
Mouse
negative regulation of protein metabolic process GO:0051248 282 0.211
muscle tissue development GO:0060537 308 0.207
Mouse
regulation of cell migration GO:0030334 219 0.205
Human Mouse
peptidyl tyrosine phosphorylation GO:0018108 143 0.204
gland development GO:0048732 330 0.201
regulation of cellular amine metabolic process GO:0033238 20 0.200
regulation of cellular ketone metabolic process GO:0010565 66 0.199
response to transforming growth factor beta GO:0071559 88 0.196
angiogenesis GO:0001525 201 0.192
cellular ketone metabolic process GO:0042180 84 0.187
branching morphogenesis of an epithelial tube GO:0048754 159 0.181
Mouse
digestive tract morphogenesis GO:0048546 147 0.176
Fly
g protein coupled receptor signaling pathway GO:0007186 243 0.173
cell growth GO:0016049 130 0.172
Mouse
negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 26 0.172
amine metabolic process GO:0009308 45 0.166
negative regulation of cellular response to growth factor stimulus GO:0090288 46 0.165
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 61 0.165
negative regulation of intracellular signal transduction GO:1902532 167 0.156
kidney development GO:0001822 213 0.156
Human Mouse
epithelial cell proliferation GO:0050673 174 0.155
Mouse
ossification GO:0001503 216 0.151
epithelial cell development GO:0002064 159 0.151
Mouse Fly
forebrain development GO:0030900 302 0.151
regionalization GO:0003002 337 0.149
connective tissue development GO:0061448 179 0.148
Mouse
negative regulation of fat cell differentiation GO:0045599 36 0.146
neuron projection guidance GO:0097485 141 0.146
Mouse
stem cell differentiation GO:0048863 268 0.144
regulation of organ morphogenesis GO:2000027 144 0.143
ameboidal type cell migration GO:0001667 128 0.141
Mouse Fly
morphogenesis of a branching structure GO:0001763 203 0.139
cellular response to transforming growth factor beta stimulus GO:0071560 88 0.137
regulation of kinase activity GO:0043549 249 0.137
Human
regulation of proteolysis GO:0030162 164 0.136
regulation of system process GO:0044057 200 0.135
Mouse
sensory organ morphogenesis GO:0090596 242 0.134
Mouse
positive regulation of cell development GO:0010720 237 0.132
Mouse
regulation of transferase activity GO:0051338 263 0.130
Human
cartilage development GO:0051216 140 0.130
cardiac muscle tissue development GO:0048738 130 0.129
Mouse
morphogenesis of a branching epithelium GO:0061138 193 0.128
regulation of cell substrate adhesion GO:0010810 73 0.128
Mouse
gastrulation GO:0007369 116 0.127
glycoprotein biosynthetic process GO:0009101 89 0.127
Mouse
apoptotic signaling pathway GO:0097190 306 0.125
Mouse
cardiocyte differentiation GO:0035051 87 0.124
Mouse
digestive tract development GO:0048565 190 0.124
negative regulation of molecular function GO:0044092 258 0.123
circulatory system process GO:0003013 197 0.122
Mouse
positive regulation of cell motility GO:2000147 116 0.122
Human Mouse
response to organonitrogen compound GO:0010243 246 0.122
regulation of protein localization GO:0032880 231 0.121
negative regulation of cellular protein metabolic process GO:0032269 247 0.120
regulation of cell cycle GO:0051726 281 0.116
Mouse
skeletal system morphogenesis GO:0048705 203 0.115
transforming growth factor beta receptor signaling pathway GO:0007179 71 0.115
mesoderm development GO:0007498 100 0.114
Mouse
positive regulation of cell death GO:0010942 224 0.114
developmental growth involved in morphogenesis GO:0060560 138 0.113
Mouse
regulation of endopeptidase activity GO:0052548 89 0.111
positive regulation of cell growth GO:0030307 33 0.110
Mouse
negative regulation of protein modification process GO:0031400 163 0.109
regulation of neuron differentiation GO:0045664 281 0.109
Mouse
axonogenesis GO:0007409 274 0.107
Mouse
negative regulation of protein phosphorylation GO:0001933 126 0.105
regulation of protein kinase activity GO:0045859 232 0.105
Human
regulation of binding GO:0051098 111 0.105
single organism cell adhesion GO:0098602 156 0.104
Mouse
bone morphogenesis GO:0060349 78 0.104
sensory perception GO:0007600 245 0.104
developmental cell growth GO:0048588 84 0.103
Mouse
negative regulation of phosphorus metabolic process GO:0010563 184 0.103
Human
regulation of hydrolase activity GO:0051336 246 0.102
negative regulation of phosphate metabolic process GO:0045936 184 0.100
Human
gonad development GO:0008406 141 0.100
Mouse
regulation of cellular amino acid metabolic process GO:0006521 5 0.100
wnt signaling pathway GO:0016055 188 0.098
cardiac muscle contraction GO:0060048 32 0.098
Mouse
regulation of organelle organization GO:0033043 289 0.097
positive regulation of protein phosphorylation GO:0001934 242 0.097
Human Mouse
positive regulation of neuron differentiation GO:0045666 141 0.096
Mouse
epidermis development GO:0008544 187 0.096
response to amino acid GO:0043200 37 0.096
stem cell development GO:0048864 219 0.095
positive regulation of cell projection organization GO:0031346 95 0.095
Mouse
regulation of peptidase activity GO:0052547 96 0.094
fibroblast growth factor receptor signaling pathway GO:0008543 46 0.092
Mouse
renal system process GO:0003014 48 0.091
Mouse
bmp signaling pathway GO:0030509 93 0.091
morphogenesis of embryonic epithelium GO:0016331 159 0.091
Mouse
chemotaxis GO:0006935 247 0.091
Human Mouse
respiratory system development GO:0060541 190 0.088
cellular response to acid chemical GO:0071229 68 0.088
action potential GO:0001508 78 0.087
positive regulation of programmed cell death GO:0043068 218 0.087
intrinsic apoptotic signaling pathway GO:0097193 132 0.087
regulation of cellular component size GO:0032535 121 0.086
Mouse
chondrocyte differentiation GO:0002062 72 0.086
regulation of fibroblast proliferation GO:0048145 34 0.086
Human
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.085
cell adhesion GO:0007155 329 0.084
Mouse
regulation of protein serine threonine kinase activity GO:0071900 157 0.084
Human
gtp catabolic process GO:0006184 143 0.083
synapse organization GO:0050808 125 0.081
formation of primary germ layer GO:0001704 77 0.080
fibroblast proliferation GO:0048144 35 0.080
Human
defense response to other organism GO:0098542 197 0.080
positive regulation of kinase activity GO:0033674 155 0.079
Human
macromolecule catabolic process GO:0009057 281 0.079
regulation of cell cycle process GO:0010564 160 0.079
negative regulation of nervous system development GO:0051961 156 0.078
bone development GO:0060348 120 0.077
digestive system development GO:0055123 200 0.076
blood circulation GO:0008015 195 0.075
Mouse
negative regulation of cell migration GO:0030336 59 0.075
Mouse
cell fate commitment GO:0045165 210 0.075
biomineral tissue development GO:0031214 64 0.075
dna metabolic process GO:0006259 303 0.074
Human
cell junction assembly GO:0034329 52 0.074
muscle system process GO:0003012 141 0.073
Mouse
cellular protein complex assembly GO:0043623 116 0.072
ventricular cardiac muscle cell action potential GO:0086005 4 0.071
salivary gland development GO:0007431 37 0.070
central nervous system neuron differentiation GO:0021953 162 0.070
developmental programmed cell death GO:0010623 41 0.070
regulation of epithelial cell proliferation GO:0050678 141 0.070
Mouse
negative regulation of bmp signaling pathway GO:0030514 35 0.070
negative regulation of immune system process GO:0002683 209 0.070
epithelial cell morphogenesis GO:0003382 41 0.070
neuron migration GO:0001764 122 0.069
neuron projection extension GO:1990138 64 0.069
Mouse
regulation of membrane potential GO:0042391 192 0.068
cell junction organization GO:0034330 77 0.068
positive regulation of apoptotic process GO:0043065 217 0.068
skeletal muscle organ development GO:0060538 163 0.068
protein catabolic process GO:0030163 221 0.067
stem cell maintenance GO:0019827 130 0.067
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.067
negative regulation of neuron differentiation GO:0045665 101 0.067
transmembrane transport GO:0055085 412 0.066
regulation of cellular response to stress GO:0080135 159 0.065
actin filament based movement GO:0030048 23 0.065
tube formation GO:0035148 140 0.064
muscle cell differentiation GO:0042692 261 0.063
Mouse
organ growth GO:0035265 117 0.063
camera type eye development GO:0043010 266 0.063
Mouse
response to light stimulus GO:0009416 135 0.062
bone mineralization GO:0030282 54 0.061
regulation of actin filament based process GO:0032970 99 0.061
regulation of striated muscle cell differentiation GO:0051153 81 0.061
regulation of transforming growth factor beta receptor signaling pathway GO:0017015 43 0.061
heart contraction GO:0060047 93 0.061
Mouse
regulation of protein transport GO:0051223 163 0.061
negative regulation of cellular component organization GO:0051129 194 0.061
tissue migration GO:0090130 68 0.061
Mouse Fly
epithelial cell migration GO:0010631 63 0.059
Mouse Fly
vegf activated neuropilin signaling pathway GO:0038190 2 0.059
Mouse
heart process GO:0003015 94 0.058
Mouse
rho protein signal transduction GO:0007266 32 0.058
single organismal cell cell adhesion GO:0016337 131 0.058
Mouse
positive regulation of nervous system development GO:0051962 221 0.057
Mouse
extrinsic apoptotic signaling pathway GO:0097191 126 0.057
Mouse
heart morphogenesis GO:0003007 178 0.057
Mouse
skin development GO:0043588 220 0.057
muscle cell development GO:0055001 133 0.056
Mouse
regulation of cell growth GO:0001558 91 0.055
Mouse
odontogenesis of dentin containing tooth GO:0042475 66 0.055
regulation of cartilage development GO:0061035 44 0.055
ear development GO:0043583 200 0.055
actin cytoskeleton organization GO:0030036 220 0.055
central nervous system neuron development GO:0021954 67 0.055
cytokine production GO:0001816 319 0.055
regulation of blood circulation GO:1903522 93 0.055
epithelium migration GO:0090132 63 0.055
Mouse Fly
cation transport GO:0006812 399 0.054
negative regulation of phosphorylation GO:0042326 166 0.054
regulation of extent of cell growth GO:0061387 52 0.054
Mouse
adherens junction assembly GO:0034333 22 0.054
protein localization to plasma membrane GO:0072659 57 0.054
multi multicellular organism process GO:0044706 109 0.054
skeletal muscle fiber development GO:0048741 58 0.053
positive regulation of neuron projection development GO:0010976 79 0.053
Mouse
actin mediated cell contraction GO:0070252 15 0.053
endochondral bone morphogenesis GO:0060350 50 0.053
cellular response to gamma radiation GO:0071480 4 0.053
odontogenesis GO:0042476 78 0.053
regulation of cell adhesion GO:0030155 154 0.052
Mouse
regulation of chromatin modification GO:1903308 57 0.052
embryonic skeletal system development GO:0048706 120 0.052
positive regulation of cytokine production GO:0001819 174 0.052
positive regulation of cellular amine metabolic process GO:0033240 5 0.052
regulation of intracellular transport GO:0032386 159 0.052
cell matrix adhesion GO:0007160 68 0.052
Mouse
telencephalon development GO:0021537 186 0.051
muscle contraction GO:0006936 101 0.050
Mouse
myeloid leukocyte activation GO:0002274 83 0.050
regulation of cellular component biogenesis GO:0044087 181 0.050
striated muscle contraction GO:0006941 45 0.050
Mouse
membrane organization GO:0061024 245 0.049
regulation of chondrocyte differentiation GO:0032330 33 0.049
positive regulation of protein modification process GO:0031401 299 0.048
Human Mouse
hemostasis GO:0007599 78 0.048
Human
regulation of cellular response to growth factor stimulus GO:0090287 82 0.048
Mouse
positive regulation of cell morphogenesis involved in differentiation GO:0010770 72 0.047
Mouse
cell type specific apoptotic process GO:0097285 268 0.046
Mouse
lymphocyte proliferation GO:0046651 164 0.046
calcium ion transport GO:0006816 159 0.046
extracellular structure organization GO:0043062 148 0.046
developmental maturation GO:0021700 193 0.046
Mouse
establishment of endothelial blood brain barrier GO:0014045 3 0.046
stem cell proliferation GO:0072089 117 0.046
regulation of chemotaxis GO:0050920 53 0.045
Mouse
regulation of dna replication GO:0006275 17 0.045
Human
response to oxygen levels GO:0070482 62 0.045
regulation of canonical wnt signaling pathway GO:0060828 82 0.045
cell cell junction organization GO:0045216 72 0.045
regulation of ion transport GO:0043269 215 0.045
appendage development GO:0048736 166 0.044
regulation of osteoblast differentiation GO:0045667 67 0.044
transmission of nerve impulse GO:0019226 76 0.044
positive regulation of smooth muscle cell migration GO:0014911 4 0.044
Mouse
cell maturation GO:0048469 127 0.044
Mouse
regulation of embryonic development GO:0045995 71 0.044
Mouse
erythrocyte differentiation GO:0030218 88 0.044
Mouse
regulation of anatomical structure size GO:0090066 178 0.043
Mouse
myotube differentiation GO:0014902 105 0.043
retinal ganglion cell axon guidance GO:0031290 18 0.043
Mouse
response to organic cyclic compound GO:0014070 198 0.043
positive regulation of cell adhesion GO:0045785 80 0.043
Mouse
regulation of myotube differentiation GO:0010830 62 0.043
positive regulation of protein transport GO:0051222 93 0.043
fat cell differentiation GO:0045444 160 0.043
urogenital system development GO:0001655 261 0.043
Human Mouse Fly
germ cell development GO:0007281 185 0.042
Fly
protein localization to membrane GO:0072657 108 0.042
regulation of secretion GO:0051046 274 0.042
anatomical structure homeostasis GO:0060249 145 0.042
Mouse
metanephros development GO:0001656 79 0.042
Human Mouse
mitral valve development GO:0003174 4 0.042
segmentation GO:0035282 93 0.041
hematopoietic progenitor cell differentiation GO:0002244 143 0.041
Mouse
regulation of blood pressure GO:0008217 93 0.041
Mouse
respiratory tube development GO:0030323 167 0.041
neural tube closure GO:0001843 90 0.041
multicellular organismal homeostasis GO:0048871 164 0.041
Mouse
divalent metal ion transport GO:0070838 172 0.040
photoreceptor cell differentiation GO:0046530 52 0.040
Mouse
ras protein signal transduction GO:0007265 77 0.040
regulation of exocytosis GO:0017157 61 0.040
regulation of wnt signaling pathway GO:0030111 123 0.040
neuronal action potential GO:0019228 54 0.040
regulation of protein secretion GO:0050708 82 0.040
tissue homeostasis GO:0001894 115 0.040
Mouse
regulation of ossification GO:0030278 112 0.040
regulation of t cell activation GO:0050863 170 0.039
negative regulation of cell development GO:0010721 169 0.039
negative regulation of apoptotic signaling pathway GO:2001234 104 0.039
Mouse
axon guidance GO:0007411 141 0.039
Mouse
regulation of cysteine type endopeptidase activity GO:2000116 65 0.039
regulation of defense response GO:0031347 233 0.038
regulation of cell projection organization GO:0031344 206 0.038
Mouse
covalent chromatin modification GO:0016569 163 0.038
multicellular organismal signaling GO:0035637 91 0.038
immune effector process GO:0002252 321 0.038
actin filament organization GO:0007015 113 0.038
regulation of cytokine production GO:0001817 266 0.038
nucleotide catabolic process GO:0009166 217 0.038
mitral valve morphogenesis GO:0003183 4 0.038
pallium development GO:0021543 120 0.038
t cell activation GO:0042110 289 0.038
endothelial cell migration GO:0043542 44 0.038
Mouse
cellular macromolecule catabolic process GO:0044265 206 0.038
cation transmembrane transport GO:0098655 266 0.038
protein maturation GO:0051604 176 0.038
lens development in camera type eye GO:0002088 62 0.038
regulation of endocytosis GO:0030100 69 0.037
negative regulation of cell cycle GO:0045786 123 0.037
regulation of neuron projection development GO:0010975 169 0.037
Mouse
microtubule based process GO:0007017 236 0.037
negative regulation of cell adhesion GO:0007162 45 0.037
Mouse
somitogenesis GO:0001756 69 0.037
positive regulation of fibroblast proliferation GO:0048146 20 0.036
Human
regulation of cellular catabolic process GO:0031329 242 0.036
syncytium formation GO:0006949 43 0.036
sequestering of calcium ion GO:0051208 18 0.036
localization within membrane GO:0051668 4 0.036
autonomic nervous system development GO:0048483 43 0.036
determination of left right symmetry GO:0007368 80 0.036
positive regulation of proteolysis GO:0045862 85 0.036
vascular endothelial growth factor signaling pathway GO:0038084 10 0.035
Mouse
compound eye development GO:0048749 1 0.035
nephron epithelium morphogenesis GO:0072088 68 0.035
Mouse
negative regulation of cell motility GO:2000146 61 0.035
Mouse
modification dependent macromolecule catabolic process GO:0043632 133 0.035
positive regulation of peptidase activity GO:0010952 49 0.035
hindbrain development GO:0030902 128 0.034
locomotory behavior GO:0007626 195 0.034
regulation of establishment of protein localization GO:0070201 181 0.034
cellular response to abiotic stimulus GO:0071214 56 0.034
Fly
neural precursor cell proliferation GO:0061351 121 0.034
Mouse
regulation of secretion by cell GO:1903530 249 0.034
regulation of homeostatic process GO:0032844 182 0.034
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.034
detection of external stimulus GO:0009581 61 0.034
regulation of muscle tissue development GO:1901861 97 0.034
epithelial tube formation GO:0072175 130 0.033
somite development GO:0061053 81 0.033
appendage morphogenesis GO:0035107 149 0.033
embryonic limb morphogenesis GO:0030326 126 0.033
positive regulation of hydrolase activity GO:0051345 148 0.033
regulation of heart contraction GO:0008016 77 0.033
negative regulation of ossification GO:0030279 49 0.033
regulation of mapk cascade GO:0043408 248 0.032
Human Mouse
development of primary sexual characteristics GO:0045137 143 0.032
Mouse
myeloid cell differentiation GO:0030099 233 0.032
Mouse
positive regulation of growth GO:0045927 104 0.032
Mouse
blood vessel endothelial cell migration GO:0043534 23 0.032
mapk cascade GO:0000165 281 0.032
Human Mouse
retina development in camera type eye GO:0060041 119 0.032
placenta development GO:0001890 140 0.032
Mouse
mesenchymal cell proliferation GO:0010463 44 0.032
development of primary female sexual characteristics GO:0046545 73 0.032
Mouse
i kappab kinase nf kappab signaling GO:0007249 85 0.031
positive regulation of lymphocyte activation GO:0051251 140 0.031
regulation of peptidyl tyrosine phosphorylation GO:0050730 93 0.031
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.031
leukocyte differentiation GO:0002521 342 0.031
negative regulation of wnt signaling pathway GO:0030178 73 0.031
cellular component assembly involved in morphogenesis GO:0010927 139 0.031
regulation of axon extension GO:0030516 43 0.031
Mouse
regulation of cytokine biosynthetic process GO:0042035 59 0.031
mesonephros development GO:0001823 97 0.031
Mouse
endomembrane system organization GO:0010256 147 0.030
nitrogen compound transport GO:0071705 271 0.030
cellular response to extracellular stimulus GO:0031668 81 0.030
mesonephric epithelium development GO:0072163 94 0.030
Mouse
positive regulation of epithelial cell proliferation GO:0050679 68 0.030
Mouse
ureteric bud development GO:0001657 94 0.030
Mouse
neural tube formation GO:0001841 108 0.030
regulation of response to wounding GO:1903034 189 0.029
Human
mesoderm formation GO:0001707 62 0.029
platelet derived growth factor receptor signaling pathway GO:0048008 32 0.029
Human
immune response regulating cell surface receptor signaling pathway GO:0002768 80 0.029
positive regulation of osteoblast differentiation GO:0045669 34 0.029
response to decreased oxygen levels GO:0036293 59 0.029
adult behavior GO:0030534 135 0.029
regulation of vesicle mediated transport GO:0060627 139 0.029
activation of adenylate cyclase activity GO:0007190 4 0.029
regulation of morphogenesis of a branching structure GO:0060688 53 0.029
regulation of transmembrane transport GO:0034762 128 0.029
regulation of fat cell differentiation GO:0045598 81 0.029
negative regulation of epithelial cell proliferation GO:0050680 64 0.029
carbohydrate metabolic process GO:0005975 230 0.028
Mouse
cellular metal ion homeostasis GO:0006875 151 0.028
renal system development GO:0072001 225 0.028
Human Mouse Fly
muscle fiber development GO:0048747 76 0.028
Mouse
intracellular protein transport GO:0006886 204 0.028
visual perception GO:0007601 52 0.028
mesenchymal cell development GO:0014031 93 0.028
cellular response to fibroblast growth factor stimulus GO:0044344 47 0.028
Mouse
modification dependent protein catabolic process GO:0019941 133 0.028
protein localization to nucleus GO:0034504 121 0.027
cytokine biosynthetic process GO:0042089 68 0.027
limb development GO:0060173 166 0.027
exocrine system development GO:0035272 45 0.027
wound healing GO:0042060 157 0.027
Human
regulation of mitotic cell cycle GO:0007346 126 0.027
Mouse
detection of stimulus GO:0051606 84 0.027
regulation of body fluid levels GO:0050878 162 0.027
Human Mouse
regulation of intracellular protein transport GO:0033157 82 0.027
muscle tissue morphogenesis GO:0060415 53 0.027
peptidyl tyrosine modification GO:0018212 145 0.027
peptidyl serine phosphorylation GO:0018105 74 0.027
inorganic ion transmembrane transport GO:0098660 234 0.027
organonitrogen compound biosynthetic process GO:1901566 192 0.026
cellular chemical homeostasis GO:0055082 215 0.026
protein modification by small protein conjugation GO:0032446 187 0.026
negative regulation of protein processing GO:0010955 79 0.026
positive regulation of axon extension GO:0045773 20 0.026
Mouse
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 62 0.026
response to hypoxia GO:0001666 58 0.026
cytokine metabolic process GO:0042107 71 0.026
mesoderm morphogenesis GO:0048332 64 0.026
regulation of neuron migration GO:2001222 22 0.026
reactive oxygen species metabolic process GO:0072593 84 0.026
metanephric nephron development GO:0072210 34 0.026
Mouse
detection of abiotic stimulus GO:0009582 60 0.025
leukocyte migration GO:0050900 124 0.025
inflammatory response GO:0006954 244 0.025
negative regulation of proteolysis GO:0045861 74 0.025
protein modification by small protein conjugation or removal GO:0070647 207 0.025
protein ubiquitination GO:0016567 171 0.025
striated muscle myosin thick filament assembly GO:0071688 1 0.025
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.025
focal adhesion assembly GO:0048041 19 0.025
satellite cell activation involved in skeletal muscle regeneration GO:0014901 3 0.025
response to inorganic substance GO:0010035 96 0.025
myotube cell development GO:0014904 60 0.025
regulation of extrinsic apoptotic signaling pathway GO:2001236 77 0.025
Mouse
actin polymerization or depolymerization GO:0008154 54 0.025
regulation of chromatin organization GO:1902275 57 0.025
heart valve development GO:0003170 23 0.024
regulation of intrinsic apoptotic signaling pathway GO:2001242 61 0.024
skeletal muscle cell differentiation GO:0035914 66 0.024
mitotic cell cycle process GO:1903047 159 0.024
cell substrate adhesion GO:0031589 130 0.024
Mouse
interleukin 8 production GO:0032637 4 0.024
regulation of systemic arterial blood pressure GO:0003073 61 0.024
Mouse
nucleoside triphosphate catabolic process GO:0009143 205 0.024
protein kinase b signaling GO:0043491 74 0.024
Human Mouse
nuclear transport GO:0051169 139 0.024
negative regulation of homeostatic process GO:0032845 71 0.024
cellular ion homeostasis GO:0006873 165 0.024
organonitrogen compound catabolic process GO:1901565 264 0.024
regulation of protein maturation GO:1903317 96 0.024
canonical wnt signaling pathway GO:0060070 130 0.024
telencephalon cell migration GO:0022029 55 0.024
ensheathment of neurons GO:0007272 76 0.024
regulation of cardiac cell fate specification GO:2000043 1 0.024
cardiac muscle cell development GO:0055013 39 0.024
Mouse
negative regulation of protein maturation GO:1903318 79 0.023
organic hydroxy compound metabolic process GO:1901615 203 0.023
positive regulation of retinal ganglion cell axon guidance GO:1902336 2 0.023
Mouse
adherens junction organization GO:0034332 28 0.023
cardiac muscle cell differentiation GO:0055007 69 0.023
Mouse
negative regulation of cellular amine metabolic process GO:0033239 1 0.023
ribose phosphate metabolic process GO:0019693 291 0.023
cellular homeostasis GO:0019725 240 0.023
purine nucleoside triphosphate metabolic process GO:0009144 226 0.023
feeding behavior GO:0007631 62 0.023
male gamete generation GO:0048232 285 0.023
regulation of angiogenesis GO:0045765 81 0.023
Mouse
limb morphogenesis GO:0035108 149 0.023
cellular response to external stimulus GO:0071496 88 0.023
transforming growth factor beta2 production GO:0032906 2 0.023
regulation of cell activation GO:0050865 289 0.023
Human
cardiac chamber development GO:0003205 108 0.023
regulation of multi organism process GO:0043900 111 0.023
columnar cuboidal epithelial cell differentiation GO:0002065 82 0.023
Fly
mitotic cytokinesis GO:0000281 4 0.023
glycosyl compound metabolic process GO:1901657 246 0.022
positive regulation of cytokine biosynthetic process GO:0042108 40 0.022
molting cycle GO:0042303 90 0.022
cardiac chamber morphogenesis GO:0003206 93 0.022
formation of organ boundary GO:0010160 1 0.022
cerebral cortex development GO:0021987 86 0.022
regulation of skeletal muscle fiber development GO:0048742 36 0.022
female sex differentiation GO:0046660 84 0.022
Mouse
cellular calcium ion homeostasis GO:0006874 119 0.022
divalent inorganic cation homeostasis GO:0072507 138 0.022
positive regulation of mapk cascade GO:0043410 170 0.022
Human Mouse
negative regulation of hydrolase activity GO:0051346 71 0.022
rhodopsin mediated signaling pathway GO:0016056 4 0.022
cell fate specification GO:0001708 72 0.022
myosin filament assembly GO:0031034 2 0.022
cell recognition GO:0008037 83 0.022
cation homeostasis GO:0055080 212 0.022
oxidation reduction process GO:0055114 342 0.022
gtp metabolic process GO:0046039 144 0.021
mesodermal cell migration GO:0008078 4 0.021
layer formation in cerebral cortex GO:0021819 13 0.021
salivary gland morphogenesis GO:0007435 33 0.021
branching involved in salivary gland morphogenesis GO:0060445 26 0.021

Pdgfa disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.073
musculoskeletal system disease DOID:17 0 0.073
muscular disease DOID:0080000 0 0.050
cancer DOID:162 0 0.032
disease of cellular proliferation DOID:14566 0 0.032
organ system cancer DOID:0050686 0 0.025
nervous system disease DOID:863 0 0.023
neuromuscular disease DOID:440 0 0.021
neuropathy DOID:870 0 0.021