Mus musculus

31 known processes

Pacs1

phosphofurin acidic cluster sorting protein 1

(Aliases: AI325977,MGC37046)

Pacs1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
ras protein signal transduction GO:0007265 77 0.388
small gtpase mediated signal transduction GO:0007264 97 0.378
rho protein signal transduction GO:0007266 32 0.219
ribonucleotide catabolic process GO:0009261 208 0.162
gtp metabolic process GO:0046039 144 0.141
regulation of ras gtpase activity GO:0032318 88 0.126
histone modification GO:0016570 159 0.126
myotube differentiation GO:0014902 105 0.110
regulation of purine nucleotide catabolic process GO:0033121 122 0.108
nucleoside triphosphate catabolic process GO:0009143 205 0.104
regulation of nucleotide metabolic process GO:0006140 169 0.097
guanosine containing compound catabolic process GO:1901069 144 0.096
purine ribonucleotide metabolic process GO:0009150 290 0.084
regulation of purine nucleotide metabolic process GO:1900542 169 0.083
ribose phosphate metabolic process GO:0019693 291 0.082
nucleobase containing small molecule metabolic process GO:0055086 352 0.082
asymmetric neuroblast division GO:0055059 1 0.080
amine metabolic process GO:0009308 45 0.078
chromatin modification GO:0016568 187 0.077
nucleotide catabolic process GO:0009166 217 0.075
positive regulation of purine nucleotide catabolic process GO:0033123 88 0.075
nucleoside phosphate metabolic process GO:0006753 338 0.075
regulation of cellular amino acid metabolic process GO:0006521 5 0.072
nucleoside catabolic process GO:0009164 206 0.072
regulation of cell projection organization GO:0031344 206 0.069
ribonucleoside triphosphate metabolic process GO:0009199 220 0.068
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.067
gtp catabolic process GO:0006184 143 0.066
embryonic appendage morphogenesis GO:0035113 126 0.065
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.064
purine nucleoside triphosphate catabolic process GO:0009146 203 0.064
glycosyl compound metabolic process GO:1901657 246 0.064
glycosyl compound catabolic process GO:1901658 206 0.063
purine nucleotide metabolic process GO:0006163 302 0.063
nucleoside metabolic process GO:0009116 246 0.061
negative regulation of molecular function GO:0044092 258 0.061
positive regulation of binding GO:0051099 49 0.061
Rat
regulation of ras protein signal transduction GO:0046578 114 0.060
muscle cell differentiation GO:0042692 261 0.059
regulation of gtp catabolic process GO:0033124 113 0.059
cellular amine metabolic process GO:0044106 44 0.058
regulation of chromatin modification GO:1903308 57 0.056
axonogenesis GO:0007409 274 0.056
regulation of cellular amine metabolic process GO:0033238 20 0.055
regionalization GO:0003002 337 0.054
carbohydrate derivative catabolic process GO:1901136 231 0.054
retrograde transport endosome to golgi GO:0042147 2 0.053
cellular ketone metabolic process GO:0042180 84 0.051
cellular homeostasis GO:0019725 240 0.051
regulation of anatomical structure size GO:0090066 178 0.051
asymmetric stem cell division GO:0098722 3 0.051
positive regulation of nucleoside metabolic process GO:0045979 91 0.051
ion transmembrane transport GO:0034220 361 0.050
nucleotide metabolic process GO:0009117 332 0.050
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.050
positive regulation of gtp catabolic process GO:0033126 85 0.050
positive regulation of cellular catabolic process GO:0031331 148 0.049
blood circulation GO:0008015 195 0.048
regulation of cellular catabolic process GO:0031329 242 0.048
regulation of cellular ketone metabolic process GO:0010565 66 0.047
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.047
purine nucleotide catabolic process GO:0006195 211 0.046
purine nucleoside triphosphate metabolic process GO:0009144 226 0.045
ribonucleoside catabolic process GO:0042454 206 0.044
positive regulation of cellular amine metabolic process GO:0033240 5 0.043
positive regulation of nucleotide catabolic process GO:0030813 88 0.043
regulation of vesicle mediated transport GO:0060627 139 0.043
cilium morphogenesis GO:0060271 102 0.042
carbohydrate metabolic process GO:0005975 230 0.042
cellular amino acid metabolic process GO:0006520 103 0.042
ribonucleotide metabolic process GO:0009259 291 0.041
cellular ion homeostasis GO:0006873 165 0.041
organophosphate catabolic process GO:0046434 232 0.041
heterocycle catabolic process GO:0046700 280 0.040
chromatin organization GO:0006325 206 0.039
cation transmembrane transport GO:0098655 266 0.039
protein localization to organelle GO:0033365 185 0.038
positive regulation of mitotic cell cycle GO:0045931 41 0.037
regulation of organelle organization GO:0033043 289 0.037
regulation of hydrolase activity GO:0051336 246 0.037
cell division GO:0051301 120 0.036
cellular macromolecule catabolic process GO:0044265 206 0.036
inorganic cation transmembrane transport GO:0098662 207 0.036
negative regulation of cellular component organization GO:0051129 194 0.036
nucleoside triphosphate metabolic process GO:0009141 230 0.036
purine containing compound catabolic process GO:0072523 213 0.036
cellular nitrogen compound catabolic process GO:0044270 280 0.035
forebrain development GO:0030900 302 0.035
regulation of cell cycle GO:0051726 281 0.034
divalent inorganic cation homeostasis GO:0072507 138 0.034
guanosine containing compound metabolic process GO:1901068 144 0.034
purine ribonucleotide catabolic process GO:0009154 208 0.033
organic cyclic compound catabolic process GO:1901361 295 0.033
positive regulation of cell cycle GO:0045787 92 0.033
plasma membrane organization GO:0007009 90 0.032
Human
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.032
regulation of neuron differentiation GO:0045664 281 0.032
aromatic compound catabolic process GO:0019439 286 0.032
regulation of chromosome organization GO:0033044 83 0.032
organonitrogen compound catabolic process GO:1901565 264 0.032
regulation of intracellular transport GO:0032386 159 0.031
regulation of cell growth by extracellular stimulus GO:0001560 2 0.031
purine containing compound metabolic process GO:0072521 311 0.031
cardiac muscle tissue development GO:0048738 130 0.031
cation homeostasis GO:0055080 212 0.031
carbohydrate biosynthetic process GO:0016051 74 0.031
cytoplasmic transport GO:0016482 234 0.031
appendage development GO:0048736 166 0.031
negative regulation of nervous system development GO:0051961 156 0.031
regulation of actin cytoskeleton organization GO:0032956 84 0.031
muscle tissue development GO:0060537 308 0.031
regulation of secretion GO:0051046 274 0.030
regulation of rho protein signal transduction GO:0035023 71 0.030
microtubule cytoskeleton organization GO:0000226 157 0.030
peptidyl serine modification GO:0018209 83 0.029
ribonucleoside metabolic process GO:0009119 245 0.029
internal protein amino acid acetylation GO:0006475 42 0.029
regulation of proteolysis GO:0030162 164 0.029
organelle fission GO:0048285 170 0.029
regulation of clathrin mediated endocytosis GO:2000369 4 0.029
purine nucleoside catabolic process GO:0006152 205 0.029
histone acetylation GO:0016573 41 0.029
negative regulation of phosphorus metabolic process GO:0010563 184 0.028
regulation of nucleoside metabolic process GO:0009118 130 0.028
regulation of transferase activity GO:0051338 263 0.028
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.028
response to peptide GO:1901652 136 0.028
sequestering of metal ion GO:0051238 19 0.028
negative regulation of hydrolase activity GO:0051346 71 0.028
cellular response to cytokine stimulus GO:0071345 189 0.027
negative regulation of cell development GO:0010721 169 0.027
negative regulation of protein metabolic process GO:0051248 282 0.027
positive regulation of cell projection organization GO:0031346 95 0.026
cellular chemical homeostasis GO:0055082 215 0.026
purine nucleoside metabolic process GO:0042278 241 0.026
nucleoside phosphate catabolic process GO:1901292 222 0.026
skeletal system development GO:0001501 356 0.026
negative regulation of synapse assembly GO:0051964 3 0.025
regulation of cellular component biogenesis GO:0044087 181 0.025
positive regulation of gtpase activity GO:0043547 85 0.025
chemotaxis GO:0006935 247 0.025
negative regulation of intracellular signal transduction GO:1902532 167 0.025
positive regulation of nucleotide metabolic process GO:0045981 114 0.025
regulation of histone modification GO:0031056 56 0.025
protein ubiquitination GO:0016567 171 0.025
ubiquitin dependent protein catabolic process GO:0006511 129 0.025
protein acylation GO:0043543 64 0.024
g protein coupled receptor signaling pathway GO:0007186 243 0.024
epithelial cell proliferation GO:0050673 174 0.023
mapk cascade GO:0000165 281 0.023
developmental maturation GO:0021700 193 0.023
regulation of cell growth GO:0001558 91 0.023
regulation of cell motility GO:2000145 236 0.023
intra golgi vesicle mediated transport GO:0006891 1 0.023
jnk cascade GO:0007254 72 0.023
protein modification by small protein conjugation or removal GO:0070647 207 0.023
striated muscle cell development GO:0055002 125 0.022
stress activated mapk cascade GO:0051403 80 0.022
regulation of cellular component size GO:0032535 121 0.022
regulation of rho gtpase activity GO:0032319 58 0.022
cellular response to acidic ph GO:0071468 4 0.021
purine ribonucleoside metabolic process GO:0046128 241 0.021
cell maturation GO:0048469 127 0.021
ribonucleoside triphosphate catabolic process GO:0009203 199 0.021
methylation GO:0032259 134 0.021
compound eye development GO:0048749 1 0.021
neural tube development GO:0021915 160 0.020
monosaccharide metabolic process GO:0005996 106 0.020
positive regulation of organelle organization GO:0010638 128 0.020
response to insulin GO:0032868 100 0.020
second messenger mediated signaling GO:0019932 73 0.020
cellular response to peptide GO:1901653 92 0.020
regulation of mitotic cell cycle GO:0007346 126 0.020
appendage morphogenesis GO:0035107 149 0.020
muscle cell development GO:0055001 133 0.020
regulation of transmembrane transport GO:0034762 128 0.020
cellular response to hormone stimulus GO:0032870 150 0.020
engulfment of apoptotic cell GO:0043652 3 0.019
regulation of binding GO:0051098 111 0.019
Rat
morphogenesis of embryonic epithelium GO:0016331 159 0.019
limb morphogenesis GO:0035108 149 0.019
regulation of kinase activity GO:0043549 249 0.019
peptidyl amino acid modification GO:0018193 336 0.019
regulation of system process GO:0044057 200 0.019
carbon catabolite activation of transcription from rna polymerase ii promoter GO:0000436 4 0.019
stress activated protein kinase signaling cascade GO:0031098 81 0.019
peptidyl serine phosphorylation GO:0018105 74 0.018
cellular calcium ion homeostasis GO:0006874 119 0.018
carbohydrate homeostasis GO:0033500 128 0.018
regulation of mapk cascade GO:0043408 248 0.018
regulation of metal ion transport GO:0010959 106 0.018
blood vessel morphogenesis GO:0048514 285 0.018
calcium ion homeostasis GO:0055074 127 0.018
positive regulation of cell cycle process GO:0090068 61 0.018
purine ribonucleoside catabolic process GO:0046130 205 0.018
modification dependent protein catabolic process GO:0019941 133 0.018
myotube cell development GO:0014904 60 0.018
positive regulation of nervous system development GO:0051962 221 0.018
protein autophosphorylation GO:0046777 61 0.018
protein targeting GO:0006605 143 0.017
notch signaling pathway GO:0007219 71 0.017
embryonic limb morphogenesis GO:0030326 126 0.017
detection of chemical stimulus involved in sensory perception of taste GO:0050912 3 0.017
nuclear division GO:0000280 158 0.017
mitotic cell cycle GO:0000278 195 0.017
regulation of inositol trisphosphate biosynthetic process GO:0032960 3 0.017
regulation of apoptotic signaling pathway GO:2001233 197 0.017
cellular protein catabolic process GO:0044257 155 0.017
cellular divalent inorganic cation homeostasis GO:0072503 127 0.017
circadian rhythm GO:0007623 114 0.017
smoothened signaling pathway GO:0007224 105 0.017
central nervous system neuron differentiation GO:0021953 162 0.016
mitotic cytokinesis GO:0000281 4 0.016
cellular response to insulin stimulus GO:0032869 78 0.016
regulation of homeostatic process GO:0032844 182 0.016
actin cytoskeleton organization GO:0030036 220 0.016
regulation of neuron projection development GO:0010975 169 0.016
immune response regulating signaling pathway GO:0002764 125 0.016
organophosphate biosynthetic process GO:0090407 122 0.016
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.016
ameboidal type cell migration GO:0001667 128 0.016
locomotory behavior GO:0007626 195 0.016
interleukin 8 production GO:0032637 4 0.016
positive regulation of protein kinase activity GO:0045860 144 0.016
exocytosis GO:0006887 121 0.016
photoreceptor cell differentiation GO:0046530 52 0.016
positive regulation of transferase activity GO:0051347 167 0.016
lateral line system development GO:0048925 1 0.015
negative regulation of organelle organization GO:0010639 90 0.015
b cell differentiation GO:0030183 78 0.015
regulation of secretion by cell GO:1903530 249 0.015
regulation of insulin receptor signaling pathway GO:0046626 21 0.015
regulation of chromatin organization GO:1902275 57 0.015
response to peptide hormone GO:0043434 127 0.015
regulation of cell cycle process GO:0010564 160 0.015
photoreceptor cell morphogenesis GO:0008594 3 0.015
regulation of nucleotide catabolic process GO:0030811 122 0.015
divalent inorganic cation transport GO:0072511 178 0.015
signal transduction in absence of ligand GO:0038034 55 0.015
regulation of leukocyte differentiation GO:1902105 159 0.015
positive regulation of cell activation GO:0050867 158 0.015
establishment or maintenance of cell polarity GO:0007163 86 0.015
regulation of striated muscle cell differentiation GO:0051153 81 0.015
regulation of protein binding GO:0043393 60 0.015
Rat
cellular response to biotic stimulus GO:0071216 92 0.015
anion transport GO:0006820 177 0.015
peptidyl lysine modification GO:0018205 77 0.015
sensory system development GO:0048880 3 0.015
positive regulation of cell motility GO:2000147 116 0.015
regulation of peptidyl lysine acetylation GO:2000756 22 0.014
sequestering of calcium ion GO:0051208 18 0.014
striated muscle tissue development GO:0014706 293 0.014
immune response activating cell surface receptor signaling pathway GO:0002429 72 0.014
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 40 0.014
cell growth GO:0016049 130 0.014
cation transport GO:0006812 399 0.014
microtubule based process GO:0007017 236 0.014
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.014
synapse organization GO:0050808 125 0.014
regulation of ion transport GO:0043269 215 0.014
stem cell maintenance GO:0019827 130 0.014
membrane organization GO:0061024 245 0.014
Human
cellular metal ion homeostasis GO:0006875 151 0.014
neuron projection guidance GO:0097485 141 0.014
heart process GO:0003015 94 0.014
maintenance of location GO:0051235 89 0.014
mitotic nuclear division GO:0007067 48 0.013
mitotic cell cycle process GO:1903047 159 0.013
protein polymerization GO:0051258 57 0.013
positive regulation of protein modification process GO:0031401 299 0.013
regulation of cell division GO:0051302 76 0.013
calcium ion transport GO:0006816 159 0.013
insulin receptor signaling pathway GO:0008286 49 0.013
sensory perception GO:0007600 245 0.013
regulation of store operated calcium entry GO:2001256 4 0.013
negative regulation of muscle cell differentiation GO:0051148 33 0.013
establishment or maintenance of microtubule cytoskeleton polarity GO:0030951 1 0.013
regulation of ion transmembrane transport GO:0034765 119 0.013
regulation of histone acetylation GO:0035065 19 0.013
cellular protein complex assembly GO:0043623 116 0.013
protein maturation GO:0051604 176 0.013
nucleoside phosphate biosynthetic process GO:1901293 79 0.013
immune response regulating cell surface receptor signaling pathway GO:0002768 80 0.013
peptidyl threonine phosphorylation GO:0018107 31 0.013
vesicle organization GO:0016050 60 0.013
camp metabolic process GO:0046058 40 0.013
regulation of cell migration GO:0030334 219 0.013
regulation of cell activation GO:0050865 289 0.013
protein import into nucleus GO:0006606 95 0.013
synaptic transmission GO:0007268 329 0.013
glucose homeostasis GO:0042593 128 0.013
cellular response to lipopolysaccharide GO:0071222 77 0.013
organonitrogen compound biosynthetic process GO:1901566 192 0.013
peptidyl tyrosine phosphorylation GO:0018108 143 0.013
apoptotic signaling pathway GO:0097190 306 0.013
cellular glucose homeostasis GO:0001678 52 0.013
covalent chromatin modification GO:0016569 163 0.013
germline cell cycle switching mitotic to meiotic cell cycle GO:0051729 1 0.013
actin filament polymerization GO:0030041 44 0.013
lung development GO:0030324 164 0.013
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.012
tissue migration GO:0090130 68 0.012
regulation of cell adhesion GO:0030155 154 0.012
macromolecule catabolic process GO:0009057 281 0.012
regulation of endopeptidase activity GO:0052548 89 0.012
carbohydrate derivative biosynthetic process GO:1901137 183 0.012
positive regulation of cell cycle phase transition GO:1901989 17 0.012
positive regulation of hydrolase activity GO:0051345 148 0.012
dna modification GO:0006304 50 0.012
positive regulation of chromatin modification GO:1903310 28 0.012
regulation of calcium ion transmembrane transporter activity GO:1901019 20 0.012
cilium assembly GO:0042384 81 0.012
cyclic nucleotide metabolic process GO:0009187 59 0.012
wnt signaling pathway GO:0016055 188 0.012
calcium mediated signaling GO:0019722 46 0.012
homeostasis of number of cells GO:0048872 210 0.012
regulation of cellular response to growth factor stimulus GO:0090287 82 0.012
neuron projection extension GO:1990138 64 0.012
skeletal muscle fiber development GO:0048741 58 0.012
histone deubiquitination GO:0016578 2 0.012
regulation of blood circulation GO:1903522 93 0.012
regulation of mitotic cell cycle phase transition GO:1901990 73 0.012
leukocyte differentiation GO:0002521 342 0.012
positive regulation of cell migration GO:0030335 109 0.012
actin filament organization GO:0007015 113 0.012
cellular carbohydrate metabolic process GO:0044262 119 0.012
regulation of ral gtpase activity GO:0032315 4 0.012
protein localization to plasma membrane GO:0072659 57 0.012
Human
cellular response to hexose stimulus GO:0071331 47 0.012
transmembrane transport GO:0055085 412 0.011
activation of immune response GO:0002253 138 0.011
lipid localization GO:0010876 126 0.011
inorganic ion transmembrane transport GO:0098660 234 0.011
innate immune response GO:0045087 157 0.011
calcium ion transport into cytosol GO:0060402 48 0.011
meiotic nuclear division GO:0007126 115 0.011
regulation of protein processing GO:0070613 96 0.011
embryonic skeletal system development GO:0048706 120 0.011
multicellular organismal signaling GO:0035637 91 0.011
negative regulation of protein phosphorylation GO:0001933 126 0.011
positive regulation of protein phosphorylation GO:0001934 242 0.011
muscle fiber development GO:0048747 76 0.011
positive regulation of histone h3 k27 methylation GO:0061087 4 0.011
t cell activation GO:0042110 289 0.011
macromolecule methylation GO:0043414 120 0.011
translation GO:0006412 93 0.011
regulation of feeding behavior GO:0060259 3 0.011
leukocyte homeostasis GO:0001776 79 0.011
negative regulation of cell cycle GO:0045786 123 0.011
spongiotrophoblast layer developmental growth GO:0090214 3 0.011
renal system development GO:0072001 225 0.011
positive regulation of ras gtpase activity GO:0032320 65 0.011
cellular response to ethanol GO:0071361 3 0.011
neural precursor cell proliferation GO:0061351 121 0.011
developmental growth involved in morphogenesis GO:0060560 138 0.011
cardiac muscle cell differentiation GO:0055007 69 0.011
regulation of cell projection assembly GO:0060491 38 0.011
response to ph GO:0009268 14 0.011
regulation of g protein coupled receptor protein signaling pathway GO:0008277 37 0.011
synaptic vesicle docking involved in exocytosis GO:0016081 4 0.011
regulation of muscle tissue development GO:1901861 97 0.011
dna methylation GO:0006306 43 0.011
mammary gland epithelium development GO:0061180 65 0.010
regulation of exocytosis GO:0017157 61 0.010
regulation of peptidyl serine phosphorylation GO:0033135 39 0.010
meiotic cell cycle GO:0051321 122 0.010
lipid biosynthetic process GO:0008610 179 0.010
actin polymerization or depolymerization GO:0008154 54 0.010
protein processing GO:0016485 163 0.010
endocrine system development GO:0035270 98 0.010
negative regulation of striated muscle cell differentiation GO:0051154 14 0.010
positive regulation of cell development GO:0010720 237 0.010
camp biosynthetic process GO:0006171 31 0.010
cognition GO:0050890 149 0.010
mesoderm development GO:0007498 100 0.010
fat cell differentiation GO:0045444 160 0.010
negative regulation of kinase activity GO:0033673 81 0.010
regulation of t cell activation GO:0050863 170 0.010

Pacs1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
central nervous system disease DOID:331 0 0.038
disease of anatomical entity DOID:7 0 0.038
nervous system disease DOID:863 0 0.038
brain disease DOID:936 0 0.030
neurodegenerative disease DOID:1289 0 0.013