Mus musculus

129 known processes

Agap2

ArfGAP with GTPase domain, ankyrin repeat and PH domain 2

(Aliases: Centg1,mKIAA0167)

Agap2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
gliogenesis GO:0042063 141 0.603
g protein coupled receptor signaling pathway GO:0007186 243 0.496
leukocyte differentiation GO:0002521 342 0.370
regulation of cellular ketone metabolic process GO:0010565 66 0.359
immune effector process GO:0002252 321 0.331
ras protein signal transduction GO:0007265 77 0.331
cellular nitrogen compound catabolic process GO:0044270 280 0.313
Mouse Worm Fly
blood circulation GO:0008015 195 0.306
small gtpase mediated signal transduction GO:0007264 97 0.306
cellular amino acid metabolic process GO:0006520 103 0.303
rho protein signal transduction GO:0007266 32 0.296
purine ribonucleotide metabolic process GO:0009150 290 0.289
Mouse Worm Fly
ribonucleotide catabolic process GO:0009261 208 0.258
Mouse Worm Fly
nucleoside catabolic process GO:0009164 206 0.256
Mouse Worm Fly
cellular ketone metabolic process GO:0042180 84 0.253
ribonucleoside metabolic process GO:0009119 245 0.248
Mouse Worm Fly
regulation of cellular amino acid metabolic process GO:0006521 5 0.248
cell activation involved in immune response GO:0002263 126 0.226
amine metabolic process GO:0009308 45 0.223
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.221
purine containing compound metabolic process GO:0072521 311 0.217
Mouse Worm Fly
nucleoside phosphate metabolic process GO:0006753 338 0.214
Mouse Worm Fly
divalent inorganic cation homeostasis GO:0072507 138 0.213
nucleotide catabolic process GO:0009166 217 0.197
Mouse Worm Fly
positive regulation of nucleotide catabolic process GO:0030813 88 0.194
Worm Fly
heterocycle catabolic process GO:0046700 280 0.185
Mouse Worm Fly
negative regulation of homeostatic process GO:0032845 71 0.183
ribonucleoside triphosphate catabolic process GO:0009203 199 0.179
Mouse Worm Fly
regulation of hydrolase activity GO:0051336 246 0.179
Worm Fly
purine nucleotide metabolic process GO:0006163 302 0.176
Mouse Worm Fly
nucleoside triphosphate metabolic process GO:0009141 230 0.175
Mouse Worm Fly
peptidyl amino acid modification GO:0018193 336 0.173
positive regulation of protein modification process GO:0031401 299 0.173
Rat
regulation of purine nucleotide catabolic process GO:0033121 122 0.173
Worm Fly
cation homeostasis GO:0055080 212 0.172
skeletal muscle organ development GO:0060538 163 0.172
cytosolic calcium ion homeostasis GO:0051480 70 0.170
negative regulation of cellular component organization GO:0051129 194 0.169
urogenital system development GO:0001655 261 0.168
positive regulation of nucleotide metabolic process GO:0045981 114 0.166
Worm Fly
synaptic transmission GO:0007268 329 0.163
cation transport GO:0006812 399 0.163
positive regulation of protein phosphorylation GO:0001934 242 0.160
Rat
sensory organ morphogenesis GO:0090596 242 0.158
nucleobase containing small molecule metabolic process GO:0055086 352 0.158
Mouse Worm Fly
organonitrogen compound catabolic process GO:1901565 264 0.157
Mouse Worm Fly
positive regulation of programmed cell death GO:0043068 218 0.155
regulation of cell migration GO:0030334 219 0.154
organic cyclic compound catabolic process GO:1901361 295 0.154
Mouse Worm Fly
dna metabolic process GO:0006259 303 0.145
guanosine containing compound metabolic process GO:1901068 144 0.141
Mouse Worm Fly
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.139
Worm Fly
positive regulation of hydrolase activity GO:0051345 148 0.137
Worm Fly
response to growth factor GO:0070848 198 0.136
positive regulation of gtpase activity GO:0043547 85 0.135
Worm Fly
regulation of myeloid cell differentiation GO:0045637 96 0.135
mapk cascade GO:0000165 281 0.134
purine nucleoside catabolic process GO:0006152 205 0.132
Mouse Worm Fly
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.132
leukocyte activation involved in immune response GO:0002366 126 0.131
metal ion homeostasis GO:0055065 189 0.131
stem cell differentiation GO:0048863 268 0.130
cellular response to growth factor stimulus GO:0071363 197 0.128
stem cell maintenance GO:0019827 130 0.125
purine nucleoside triphosphate metabolic process GO:0009144 226 0.123
Mouse Worm Fly
cellular calcium ion homeostasis GO:0006874 119 0.122
carbohydrate derivative catabolic process GO:1901136 231 0.122
Mouse Worm Fly
muscle tissue development GO:0060537 308 0.120
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.119
Mouse Worm Fly
regulation of leukocyte mediated immunity GO:0002703 104 0.118
regulation of leukocyte differentiation GO:1902105 159 0.116
inflammatory response GO:0006954 244 0.115
positive regulation of apoptotic process GO:0043065 217 0.113
cellular metal ion homeostasis GO:0006875 151 0.113
regulation of cellular amine metabolic process GO:0033238 20 0.112
leukocyte migration GO:0050900 124 0.109
nucleoside triphosphate catabolic process GO:0009143 205 0.108
Mouse Worm Fly
cell adhesion GO:0007155 329 0.108
generation of precursor metabolites and energy GO:0006091 103 0.107
cerebral cortex development GO:0021987 86 0.106
positive regulation of mapk cascade GO:0043410 170 0.105
regulation of neuron apoptotic process GO:0043523 122 0.105
Human Rat
axonogenesis GO:0007409 274 0.102
positive regulation of kinase activity GO:0033674 155 0.101
Rat
positive regulation of nucleoside metabolic process GO:0045979 91 0.100
Worm Fly
oxidation reduction process GO:0055114 342 0.099
positive regulation of gtp catabolic process GO:0033126 85 0.099
Worm Fly
myeloid leukocyte differentiation GO:0002573 119 0.098
response to organonitrogen compound GO:0010243 246 0.097
regulation of homeostatic process GO:0032844 182 0.096
ribose phosphate metabolic process GO:0019693 291 0.095
Mouse Worm Fly
mammary gland epithelium development GO:0061180 65 0.094
regulation of hormone levels GO:0010817 211 0.094
regulation of defense response GO:0031347 233 0.092
regulation of purine nucleotide metabolic process GO:1900542 169 0.092
Worm Fly
neuron projection guidance GO:0097485 141 0.091
purine ribonucleoside catabolic process GO:0046130 205 0.089
Mouse Worm Fly
positive regulation of defense response GO:0031349 124 0.089
cellular lipid metabolic process GO:0044255 323 0.088
skeletal system morphogenesis GO:0048705 203 0.088
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 87 0.087
regulation of gtp catabolic process GO:0033124 113 0.087
Worm Fly
purine nucleotide catabolic process GO:0006195 211 0.085
Mouse Worm Fly
cell chemotaxis GO:0060326 81 0.085
mitotic cell cycle GO:0000278 195 0.085
embryonic organ morphogenesis GO:0048562 276 0.084
lymphocyte differentiation GO:0030098 242 0.084
positive regulation of lymphocyte proliferation GO:0050671 70 0.084
positive regulation of cellular amine metabolic process GO:0033240 5 0.084
cellular ion homeostasis GO:0006873 165 0.084
cellular modified amino acid metabolic process GO:0006575 63 0.083
cellular response to hormone stimulus GO:0032870 150 0.081
negative regulation of protein metabolic process GO:0051248 282 0.081
Human
response to radiation GO:0009314 165 0.081
macromolecule catabolic process GO:0009057 281 0.081
Human Mouse
purine containing compound catabolic process GO:0072523 213 0.080
Mouse Worm Fly
nucleoside phosphate catabolic process GO:1901292 222 0.080
Mouse Worm Fly
negative regulation of neuron death GO:1901215 98 0.080
Human Rat
positive regulation of inflammatory response GO:0050729 47 0.079
cellular divalent inorganic cation homeostasis GO:0072503 127 0.079
divalent metal ion transport GO:0070838 172 0.079
leukocyte mediated immunity GO:0002443 174 0.079
immunoglobulin production GO:0002377 73 0.078
positive regulation of cell death GO:0010942 224 0.078
ribonucleotide metabolic process GO:0009259 291 0.077
Mouse Worm Fly
guanosine containing compound catabolic process GO:1901069 144 0.077
Mouse Worm Fly
positive regulation of cell activation GO:0050867 158 0.076
peptidyl tyrosine modification GO:0018212 145 0.075
alpha beta t cell differentiation GO:0046632 69 0.075
divalent inorganic cation transport GO:0072511 178 0.075
positive regulation of myeloid cell differentiation GO:0045639 43 0.075
regulation of cytokine production GO:0001817 266 0.073
cell fate commitment GO:0045165 210 0.073
Worm
regulation of myeloid leukocyte differentiation GO:0002761 58 0.072
positive regulation of purine nucleotide catabolic process GO:0033123 88 0.072
Worm Fly
regulation of cell projection organization GO:0031344 206 0.071
response to light stimulus GO:0009416 135 0.071
peptidyl tyrosine phosphorylation GO:0018108 143 0.070
syncytium formation GO:0006949 43 0.070
regulation of neuron death GO:1901214 134 0.069
Human Rat
ameboidal type cell migration GO:0001667 128 0.069
glycosyl compound catabolic process GO:1901658 206 0.069
Mouse Worm Fly
sequestering of metal ion GO:0051238 19 0.068
second messenger mediated signaling GO:0019932 73 0.067
apoptotic signaling pathway GO:0097190 306 0.067
Rat
leukocyte proliferation GO:0070661 172 0.066
eosinophil migration GO:0072677 3 0.065
cellular response to peptide GO:1901653 92 0.065
response to interleukin 15 GO:0070672 3 0.065
organophosphate catabolic process GO:0046434 232 0.064
Mouse Worm Fly
positive regulation of cellular catabolic process GO:0031331 148 0.063
Worm Fly
osteoclast differentiation GO:0030316 62 0.063
regulation of nucleotide metabolic process GO:0006140 169 0.062
Worm Fly
neuron death GO:0070997 154 0.062
Human Rat
cellular response to organonitrogen compound GO:0071417 145 0.062
ribonucleoside catabolic process GO:0042454 206 0.061
Mouse Worm Fly
cellular response to transforming growth factor beta stimulus GO:0071560 88 0.061
maintenance of location GO:0051235 89 0.060
regulation of neurotransmitter levels GO:0001505 87 0.060
regulation of kinase activity GO:0043549 249 0.060
Rat
transmembrane transport GO:0055085 412 0.059
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.059
Mouse Worm Fly
regulation of eosinophil migration GO:2000416 2 0.059
epithelial cell proliferation GO:0050673 174 0.059
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.058
negative regulation of intracellular signal transduction GO:1902532 167 0.058
lymphocyte mediated immunity GO:0002449 139 0.058
alpha amino acid metabolic process GO:1901605 59 0.058
sensory perception GO:0007600 245 0.057
developmental maturation GO:0021700 193 0.057
g protein coupled acetylcholine receptor signaling pathway GO:0007213 4 0.057
cellular response to peptide hormone stimulus GO:0071375 92 0.057
nucleoside metabolic process GO:0009116 246 0.057
Mouse Worm Fly
developmental growth involved in morphogenesis GO:0060560 138 0.057
regulation of neuron differentiation GO:0045664 281 0.056
regulation of cell motility GO:2000145 236 0.056
purine ribonucleoside metabolic process GO:0046128 241 0.055
Mouse Worm Fly
cytokine mediated signaling pathway GO:0019221 115 0.055
adenylate cyclase modulating g protein coupled receptor signaling pathway GO:0007188 54 0.054
myotube differentiation GO:0014902 105 0.053
regulation of cellular component biogenesis GO:0044087 181 0.053
cell type specific apoptotic process GO:0097285 268 0.053
Human Rat
regulation of nucleoside metabolic process GO:0009118 130 0.053
Worm Fly
positive regulation of leukocyte differentiation GO:1902107 86 0.053
multicellular organismal homeostasis GO:0048871 164 0.053
myeloid cell differentiation GO:0030099 233 0.052
nucleotide metabolic process GO:0009117 332 0.052
Mouse Worm Fly
cellular homeostasis GO:0019725 240 0.052
positive regulation of cytosolic calcium ion concentration GO:0007204 65 0.052
calcium ion transport GO:0006816 159 0.052
regulation of inflammatory response GO:0050727 147 0.052
asymmetric stem cell division GO:0098722 3 0.052
Worm
regulation of neuron projection development GO:0010975 169 0.051
regulation of secretion by cell GO:1903530 249 0.051
positive regulation of lymphocyte activation GO:0051251 140 0.050
synapse organization GO:0050808 125 0.050
positive regulation of myeloid leukocyte differentiation GO:0002763 26 0.050
regulation of lipid metabolic process GO:0019216 118 0.050
natural killer cell mediated cytotoxicity GO:0042267 29 0.050
aromatic compound catabolic process GO:0019439 286 0.049
Mouse Worm Fly
circulatory system process GO:0003013 197 0.049
steroid metabolic process GO:0008202 119 0.049
multicellular organismal signaling GO:0035637 91 0.049
negative regulation of glycolytic process GO:0045820 4 0.049
calcium ion homeostasis GO:0055074 127 0.049
regulation of cellular catabolic process GO:0031329 242 0.049
Worm Fly
regulation of secretion GO:0051046 274 0.049
cognition GO:0050890 149 0.049
glial cell differentiation GO:0010001 131 0.049
response to molecule of bacterial origin GO:0002237 143 0.048
cytokine production GO:0001816 319 0.048
t cell differentiation GO:0030217 174 0.048
negative regulation of neuron apoptotic process GO:0043524 92 0.047
Human Rat
learning or memory GO:0007611 148 0.046
purine nucleoside metabolic process GO:0042278 241 0.046
Mouse Worm Fly
regulation of mast cell differentiation GO:0060375 3 0.046
regulation of lymphocyte activation GO:0051249 240 0.046
protein maturation GO:0051604 176 0.045
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.045
ion transmembrane transport GO:0034220 361 0.045
exocytosis GO:0006887 121 0.045
regulation of organelle organization GO:0033043 289 0.045
lymphocyte homeostasis GO:0002260 64 0.045
regionalization GO:0003002 337 0.044
nucleoside phosphate biosynthetic process GO:1901293 79 0.044
axon ensheathment GO:0008366 76 0.044
organophosphate biosynthetic process GO:0090407 122 0.044
response to interleukin 4 GO:0070670 23 0.044
gtp metabolic process GO:0046039 144 0.043
Mouse Worm Fly
regulation of anatomical structure size GO:0090066 178 0.043
cellular chemical homeostasis GO:0055082 215 0.042
epithelial tube morphogenesis GO:0060562 303 0.042
protein processing GO:0016485 163 0.042
positive regulation of t cell activation GO:0050870 101 0.042
anion transport GO:0006820 177 0.041
positive regulation of ras gtpase activity GO:0032320 65 0.041
Worm
regulation of protein localization GO:0032880 231 0.041
regulation of cell cycle GO:0051726 281 0.041
organonitrogen compound biosynthetic process GO:1901566 192 0.041
eye photoreceptor cell differentiation GO:0001754 41 0.040
syncytium formation by plasma membrane fusion GO:0000768 42 0.040
cell division GO:0051301 120 0.040
Worm
cell killing GO:0001906 67 0.040
regulation of body fluid levels GO:0050878 162 0.040
sequestering of calcium ion GO:0051208 18 0.039
regulation of apoptotic signaling pathway GO:2001233 197 0.039
Rat
regulation of phosphate transport GO:0010966 1 0.039
negative regulation of immune system process GO:0002683 209 0.039
ribose phosphate biosynthetic process GO:0046390 59 0.039
regulation of t cell activation GO:0050863 170 0.039
mast cell proliferation GO:0070662 4 0.039
histone modification GO:0016570 159 0.039
regulation of cell shape GO:0008360 39 0.039
positive regulation of cell development GO:0010720 237 0.038
response to peptide GO:1901652 136 0.038
chromatin organization GO:0006325 206 0.038
alpha beta t cell activation GO:0046631 91 0.038
isotype switching to ige isotypes GO:0048289 7 0.037
cellular response to abiotic stimulus GO:0071214 56 0.037
regulation of carbohydrate metabolic process GO:0006109 75 0.037
chemotaxis GO:0006935 247 0.037
negative regulation of phosphate metabolic process GO:0045936 184 0.037
wnt signaling pathway GO:0016055 188 0.037
natural killer cell activation GO:0030101 44 0.037
neurotransmitter transport GO:0006836 76 0.037
hormone metabolic process GO:0042445 86 0.036
central nervous system neuron differentiation GO:0021953 162 0.036
multi multicellular organism process GO:0044706 109 0.036
protein autophosphorylation GO:0046777 61 0.036
response to temperature stimulus GO:0009266 55 0.036
tissue homeostasis GO:0001894 115 0.035
regulation of mast cell proliferation GO:0070666 4 0.035
regulation of erythrocyte differentiation GO:0045646 23 0.035
activation of mapk activity GO:0000187 59 0.035
regulation of leukocyte proliferation GO:0070663 121 0.035
calcium ion transmembrane transport GO:0070588 85 0.035
positive regulation of transferase activity GO:0051347 167 0.035
Rat
t cell activation GO:0042110 289 0.035
carbohydrate derivative biosynthetic process GO:1901137 183 0.035
positive regulation of protein kinase activity GO:0045860 144 0.035
Rat
cellular response to interleukin 4 GO:0071353 21 0.035
replacement ossification GO:0036075 26 0.035
transmission of nerve impulse GO:0019226 76 0.034
purine ribonucleotide catabolic process GO:0009154 208 0.034
Mouse Worm Fly
morphogenesis of a branching structure GO:0001763 203 0.034
response to transforming growth factor beta GO:0071559 88 0.034
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.034
chromatin modification GO:0016568 187 0.034
alcohol metabolic process GO:0006066 116 0.034
positive regulation of t cell proliferation GO:0042102 52 0.033
regulation of rho gtpase activity GO:0032319 58 0.033
glycosyl compound metabolic process GO:1901657 246 0.033
Mouse Worm Fly
positive regulation of eosinophil migration GO:2000418 2 0.033
cellular response to biotic stimulus GO:0071216 92 0.033
cation transmembrane transport GO:0098655 266 0.032
inorganic ion transmembrane transport GO:0098660 234 0.032
memory GO:0007613 58 0.032
regulation of mitotic cell cycle GO:0007346 126 0.032
response to lipopolysaccharide GO:0032496 128 0.032
leukocyte degranulation GO:0043299 27 0.032
glucose homeostasis GO:0042593 128 0.032
regulation of nucleotide catabolic process GO:0030811 122 0.032
Worm Fly
fertilization GO:0009566 127 0.031
myeloid leukocyte activation GO:0002274 83 0.031
lipid biosynthetic process GO:0008610 179 0.031
cyclic purine nucleotide metabolic process GO:0052652 43 0.031
regulation of blood vessel size GO:0050880 56 0.031
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.031
positive regulation of nervous system development GO:0051962 221 0.031
signal transduction in absence of ligand GO:0038034 55 0.031
Rat
odontogenesis of dentin containing tooth GO:0042475 66 0.031
organic hydroxy compound metabolic process GO:1901615 203 0.031
lymphocyte proliferation GO:0046651 164 0.031
cellular response to lipid GO:0071396 145 0.031
interleukin 2 biosynthetic process GO:0042094 15 0.031
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.030
mating behavior sex discrimination GO:0048047 1 0.030
carbohydrate homeostasis GO:0033500 128 0.030
calcium mediated signaling GO:0019722 46 0.030
telencephalon development GO:0021537 186 0.030
negative regulation of cellular amine metabolic process GO:0033239 1 0.030
positive regulation of monocyte chemotaxis GO:0090026 2 0.030
regulation of map kinase activity GO:0043405 120 0.030
striated muscle tissue development GO:0014706 293 0.030
regulation of cell activation GO:0050865 289 0.030
peptide secretion GO:0002790 114 0.029
negative regulation of cell development GO:0010721 169 0.029
mature dendritic cell differentiation GO:0097029 3 0.029
reactive oxygen species metabolic process GO:0072593 84 0.029
positive regulation of organelle organization GO:0010638 128 0.029
cellular amine metabolic process GO:0044106 44 0.029
appendage morphogenesis GO:0035107 149 0.029
innate immune response GO:0045087 157 0.029
detection of stimulus GO:0051606 84 0.029
negative regulation of cellular protein metabolic process GO:0032269 247 0.029
negative regulation of cell motility GO:2000146 61 0.029
cellular response to molecule of bacterial origin GO:0071219 83 0.029
action potential GO:0001508 78 0.028
regulation of system process GO:0044057 200 0.028
regulation of transporter activity GO:0032409 57 0.028
antigen receptor mediated signaling pathway GO:0050851 64 0.028
response to organic cyclic compound GO:0014070 198 0.028
covalent chromatin modification GO:0016569 163 0.028
regulation of cellular component size GO:0032535 121 0.028
membrane depolarization GO:0051899 64 0.028
gamma delta t cell activation GO:0046629 13 0.028
positive regulation of cytokine production GO:0001819 174 0.028
regulation of mapk cascade GO:0043408 248 0.028
regulation of postsynaptic membrane potential GO:0060078 48 0.027
positive regulation of response to wounding GO:1903036 66 0.027
positive regulation of rho gtpase activity GO:0032321 41 0.027
regulation of protein serine threonine kinase activity GO:0071900 157 0.027
regulation of b cell activation GO:0050864 81 0.027
negative regulation of molecular function GO:0044092 258 0.027
mitotic cell cycle process GO:1903047 159 0.027
regulation of protein kinase activity GO:0045859 232 0.027
Rat
axon guidance GO:0007411 141 0.027
mitochondrion organization GO:0007005 134 0.027
glycoprotein metabolic process GO:0009100 116 0.027
cellular carbohydrate metabolic process GO:0044262 119 0.027
t cell differentiation in thymus GO:0033077 77 0.027
mesodermal cell migration GO:0008078 4 0.027
negative regulation of apoptotic signaling pathway GO:2001234 104 0.026
Rat
nucleotide biosynthetic process GO:0009165 78 0.026
cellular amide metabolic process GO:0043603 58 0.026
negative regulation of cell migration GO:0030336 59 0.026
leukocyte apoptotic process GO:0071887 71 0.026
muscle cell differentiation GO:0042692 261 0.026
epidermis development GO:0008544 187 0.026
t cell proliferation GO:0042098 120 0.026
cell growth GO:0016049 130 0.026
negative regulation of myeloid cell differentiation GO:0045638 38 0.026
fibroblast migration GO:0010761 21 0.026
gland development GO:0048732 330 0.026
vascular process in circulatory system GO:0003018 62 0.026
cd4 positive alpha beta t cell activation GO:0035710 45 0.025
regulation of cellular carbohydrate metabolic process GO:0010675 75 0.025
purine nucleoside triphosphate catabolic process GO:0009146 203 0.025
Mouse Worm Fly
multi organism behavior GO:0051705 62 0.025
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.025
regulation of cellular response to stress GO:0080135 159 0.025
protein targeting GO:0006605 143 0.025
Mouse
digestive tract development GO:0048565 190 0.025
cytoplasmic transport GO:0016482 234 0.025
Mouse
hematopoietic progenitor cell differentiation GO:0002244 143 0.025
positive regulation of leukocyte proliferation GO:0070665 73 0.025
ribonucleoside triphosphate metabolic process GO:0009199 220 0.025
Mouse Worm Fly
mammary gland duct morphogenesis GO:0060603 38 0.025
developmental cell growth GO:0048588 84 0.025
calcium ion transport into cytosol GO:0060402 48 0.024
organelle fission GO:0048285 170 0.024
regulation of intracellular transport GO:0032386 159 0.024
organelle localization GO:0051640 179 0.024
lymphocyte activation involved in immune response GO:0002285 93 0.024
fat cell differentiation GO:0045444 160 0.024
neuron maturation GO:0042551 29 0.024
camp biosynthetic process GO:0006171 31 0.024
detection of abiotic stimulus GO:0009582 60 0.023
neuronal action potential GO:0019228 54 0.023
response to insulin GO:0032868 100 0.023
positive regulation of immune effector process GO:0002699 107 0.023
phospholipid metabolic process GO:0006644 87 0.023
regulation of rho protein signal transduction GO:0035023 71 0.023
regulation of carbohydrate catabolic process GO:0043470 12 0.023
purine ribonucleotide biosynthetic process GO:0009152 59 0.023
cell recognition GO:0008037 83 0.023
regulation of lymphocyte differentiation GO:0045619 107 0.023
macromolecule methylation GO:0043414 120 0.023
citrate metabolic process GO:0006101 3 0.023
aortic valve morphogenesis GO:0003180 4 0.023
response to oxidative stress GO:0006979 123 0.023
Mouse
regulation of leukocyte mediated cytotoxicity GO:0001910 38 0.023
microglial cell activation GO:0001774 3 0.023
angiogenesis GO:0001525 201 0.023
skeletal system development GO:0001501 356 0.023
eosinophil activation GO:0043307 1 0.023
prostate gland development GO:0030850 48 0.022
glycolytic process GO:0006096 20 0.022
cellular response to cytokine stimulus GO:0071345 189 0.022
defense response to other organism GO:0098542 197 0.022
regulation of cell division GO:0051302 76 0.022
interleukin 12 secretion GO:0072610 3 0.022
positive regulation of production of molecular mediator of immune response GO:0002702 45 0.022
regulation of striated muscle cell differentiation GO:0051153 81 0.022
regulation of circadian sleep wake cycle sleep GO:0045187 3 0.022
regulation of response to wounding GO:1903034 189 0.022
positive regulation of camp metabolic process GO:0030816 19 0.021
membrane organization GO:0061024 245 0.021
cellular response to lipopolysaccharide GO:0071222 77 0.021
appendage development GO:0048736 166 0.021
cell differentiation in spinal cord GO:0021515 53 0.021
positive regulation of leukocyte mediated immunity GO:0002705 70 0.021
regulation of ras gtpase activity GO:0032318 88 0.021
Worm
plasma membrane organization GO:0007009 90 0.021
regulation of jak stat cascade GO:0046425 34 0.021
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger GO:0007187 55 0.021
regulation of erk1 and erk2 cascade GO:0070372 71 0.021
interleukin 2 production GO:0032623 33 0.021
regulation of lymphocyte mediated immunity GO:0002706 84 0.021
regulation of exocytosis GO:0017157 61 0.021
energy reserve metabolic process GO:0006112 39 0.021
neuron migration GO:0001764 122 0.021
neuron apoptotic process GO:0051402 142 0.021
Human Rat
t cell homeostasis GO:0043029 35 0.021
positive regulation of thymocyte migration GO:2000412 2 0.021
leukocyte homeostasis GO:0001776 79 0.021
organ growth GO:0035265 117 0.021
actin cytoskeleton organization GO:0030036 220 0.021
regulation of cardiac chamber morphogenesis GO:1901219 2 0.021
nuclear division GO:0000280 158 0.021
insulin receptor signaling pathway GO:0008286 49 0.021
establishment of protein localization to organelle GO:0072594 118 0.021
Mouse
regulation of immunoglobulin production GO:0002637 42 0.020
negative regulation of nervous system development GO:0051961 156 0.020
lamellipodium organization GO:0097581 29 0.020
negative regulation of multi organism process GO:0043901 68 0.020
visual learning GO:0008542 44 0.020
alpha beta t cell activation involved in immune response GO:0002287 31 0.020
positive regulation of neuron differentiation GO:0045666 141 0.020
regulation of neuron migration GO:2001222 22 0.020
t cell differentiation involved in immune response GO:0002292 30 0.020
circadian rhythm GO:0007623 114 0.020
negative regulation of growth GO:0045926 99 0.020
regulation of gamma aminobutyric acid secretion GO:0014052 2 0.020
regulation of membrane potential GO:0042391 192 0.020
leukocyte mediated cytotoxicity GO:0001909 62 0.020
regulation of ion transmembrane transport GO:0034765 119 0.020
response to ph GO:0009268 14 0.020
actin filament organization GO:0007015 113 0.020
associative learning GO:0008306 61 0.020
somatic cell dna recombination GO:0016444 51 0.020
dna recombination GO:0006310 92 0.020
regulation of adaptive immune response GO:0002819 90 0.020
positive regulation of immunoglobulin production GO:0002639 28 0.020
negative regulation of phosphorus metabolic process GO:0010563 184 0.020
adenylate cyclase activating g protein coupled receptor signaling pathway GO:0007189 30 0.020
regulation of ion transport GO:0043269 215 0.020
negative regulation of protein modification process GO:0031400 163 0.020
protein catabolic process GO:0030163 221 0.020
Human Mouse
regulation of muscle tissue development GO:1901861 97 0.020
development of secondary male sexual characteristics GO:0046544 3 0.019
nitrogen compound transport GO:0071705 271 0.019
photoreceptor cell differentiation GO:0046530 52 0.019
heart morphogenesis GO:0003007 178 0.019
regulation of alpha beta t cell activation GO:0046634 53 0.019
response to peptide hormone GO:0043434 127 0.019
erythrocyte differentiation GO:0030218 88 0.019
positive regulation of lymphocyte mediated immunity GO:0002708 62 0.019
response to inorganic substance GO:0010035 96 0.019
regulation of isotype switching GO:0045191 22 0.019
thymocyte migration GO:0072679 2 0.019
single fertilization GO:0007338 82 0.019
metanephros development GO:0001656 79 0.019
somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 51 0.019

Agap2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.044
nervous system disease DOID:863 0 0.044