Mus musculus

0 known processes

Pycr1

pyrroline-5-carboxylate reductase 1

(Aliases: MGC11688)

Pycr1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular amino acid metabolic process GO:0006520 103 0.086
Human
ion transmembrane transport GO:0034220 361 0.085
carbohydrate metabolic process GO:0005975 230 0.068
cellular ketone metabolic process GO:0042180 84 0.065
cation transport GO:0006812 399 0.058
regulation of cellular ketone metabolic process GO:0010565 66 0.052
anion transport GO:0006820 177 0.050
carbohydrate biosynthetic process GO:0016051 74 0.048
oxidation reduction process GO:0055114 342 0.047
Human
transmembrane transport GO:0055085 412 0.047
cellular amine metabolic process GO:0044106 44 0.045
nitrogen compound transport GO:0071705 271 0.043
regulation of cellular amino acid metabolic process GO:0006521 5 0.042
organonitrogen compound biosynthetic process GO:1901566 192 0.042
Human
amine metabolic process GO:0009308 45 0.042
muscle tissue development GO:0060537 308 0.040
positive regulation of cell death GO:0010942 224 0.038
nucleobase containing small molecule metabolic process GO:0055086 352 0.037
amino acid transmembrane transport GO:0003333 37 0.037
macromolecule catabolic process GO:0009057 281 0.035
regulation of cellular amine metabolic process GO:0033238 20 0.034
folic acid containing compound metabolic process GO:0006760 3 0.033
organic acid transport GO:0015849 101 0.033
skeletal system development GO:0001501 356 0.032
wound healing GO:0042060 157 0.032
striated muscle tissue development GO:0014706 293 0.031
cation transmembrane transport GO:0098655 266 0.031
regulation of secretion by cell GO:1903530 249 0.031
regulation of secretion GO:0051046 274 0.031
connective tissue development GO:0061448 179 0.030
regulation of cell cycle GO:0051726 281 0.029
cellular homeostasis GO:0019725 240 0.029
protein catabolic process GO:0030163 221 0.029
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.028
spermatogenesis GO:0007283 284 0.028
ossification GO:0001503 216 0.028
peptidyl amino acid modification GO:0018193 336 0.028
positive regulation of programmed cell death GO:0043068 218 0.028
hexose metabolic process GO:0019318 98 0.027
cellular chemical homeostasis GO:0055082 215 0.027
nucleotide metabolic process GO:0009117 332 0.027
male gamete generation GO:0048232 285 0.027
anion transmembrane transport GO:0098656 71 0.026
monocarboxylic acid metabolic process GO:0032787 191 0.026
organic anion transport GO:0015711 137 0.026
l alpha amino acid transmembrane transport GO:1902475 23 0.025
nucleoside phosphate metabolic process GO:0006753 338 0.025
extracellular structure organization GO:0043062 148 0.025
positive regulation of protein modification process GO:0031401 299 0.025
regulation of organelle organization GO:0033043 289 0.025
negative regulation of immune system process GO:0002683 209 0.025
amino acid transport GO:0006865 61 0.025
carboxylic acid transport GO:0046942 100 0.025
reactive oxygen species metabolic process GO:0072593 84 0.024
ras protein signal transduction GO:0007265 77 0.024
positive regulation of cellular amine metabolic process GO:0033240 5 0.024
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.024
positive regulation of apoptotic process GO:0043065 217 0.023
developmental growth involved in morphogenesis GO:0060560 138 0.022
l amino acid transport GO:0015807 32 0.022
regulation of ossification GO:0030278 112 0.022
negative regulation of intracellular signal transduction GO:1902532 167 0.022
apoptotic signaling pathway GO:0097190 306 0.022
organelle assembly GO:0070925 177 0.022
negative regulation of cell proliferation GO:0008285 296 0.022
membrane organization GO:0061024 245 0.022
cell type specific apoptotic process GO:0097285 268 0.022
cellular lipid metabolic process GO:0044255 323 0.021
glucose homeostasis GO:0042593 128 0.021
multicellular organismal homeostasis GO:0048871 164 0.021
cell adhesion GO:0007155 329 0.021
glucose metabolic process GO:0006006 92 0.021
multicellular organismal signaling GO:0035637 91 0.021
sensory perception GO:0007600 245 0.021
coenzyme metabolic process GO:0006732 52 0.020
cartilage development GO:0051216 140 0.020
regulation of neuron differentiation GO:0045664 281 0.020
positive regulation of secretion GO:0051047 130 0.020
bone development GO:0060348 120 0.020
small gtpase mediated signal transduction GO:0007264 97 0.020
cytoplasmic transport GO:0016482 234 0.020
negative regulation of cellular amine metabolic process GO:0033239 1 0.019
cellular carbohydrate metabolic process GO:0044262 119 0.019
monosaccharide metabolic process GO:0005996 106 0.019
dna metabolic process GO:0006259 303 0.019
regulation of establishment of protein localization GO:0070201 181 0.019
hexose biosynthetic process GO:0019319 39 0.019
skeletal system morphogenesis GO:0048705 203 0.019
extracellular matrix organization GO:0030198 147 0.019
anatomical structure homeostasis GO:0060249 145 0.019
immune effector process GO:0002252 321 0.019
cellular metal ion homeostasis GO:0006875 151 0.019
regulation of membrane potential GO:0042391 192 0.019
Human
compound eye development GO:0048749 1 0.019
methionine transport GO:0015821 1 0.018
heterocycle catabolic process GO:0046700 280 0.018
aromatic compound catabolic process GO:0019439 286 0.018
regulation of cytokine production GO:0001817 266 0.018
reactive oxygen species biosynthetic process GO:1903409 8 0.018
regulation of cell motility GO:2000145 236 0.018
divalent metal ion transport GO:0070838 172 0.018
leukocyte differentiation GO:0002521 342 0.018
carbohydrate homeostasis GO:0033500 128 0.018
cellular modified amino acid metabolic process GO:0006575 63 0.018
neuron death GO:0070997 154 0.018
b cell activation GO:0042113 161 0.017
cytokine production GO:0001816 319 0.017
metal ion homeostasis GO:0055065 189 0.017
inflammatory response GO:0006954 244 0.017
small molecule biosynthetic process GO:0044283 132 0.017
Human
fat cell differentiation GO:0045444 160 0.017
response to organic cyclic compound GO:0014070 198 0.017
negative regulation of molecular function GO:0044092 258 0.017
response to acid chemical GO:0001101 111 0.017
locomotory behavior GO:0007626 195 0.017
purine nucleoside metabolic process GO:0042278 241 0.017
myotube differentiation GO:0014902 105 0.017
respiratory system development GO:0060541 190 0.017
cell growth GO:0016049 130 0.017
response to endoplasmic reticulum stress GO:0034976 53 0.017
neuron apoptotic process GO:0051402 142 0.017
positive regulation of secretion by cell GO:1903532 114 0.017
regulation of proteolysis GO:0030162 164 0.017
lymphocyte differentiation GO:0030098 242 0.017
microtubule based process GO:0007017 236 0.017
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.016
cellular nitrogen compound catabolic process GO:0044270 280 0.016
lateral inhibition GO:0046331 1 0.016
purine ribonucleotide metabolic process GO:0009150 290 0.016
mapk cascade GO:0000165 281 0.016
regulation of ion transport GO:0043269 215 0.016
mitotic cell cycle process GO:1903047 159 0.016
cellular macromolecule catabolic process GO:0044265 206 0.016
appendage morphogenesis GO:0035107 149 0.016
regulation of protein transport GO:0051223 163 0.016
g protein coupled receptor signaling pathway GO:0007186 243 0.016
skeletal muscle organ development GO:0060538 163 0.015
regulation of leukocyte differentiation GO:1902105 159 0.015
regulation of cell adhesion GO:0030155 154 0.015
neuronal action potential GO:0019228 54 0.015
divalent inorganic cation homeostasis GO:0072507 138 0.015
inorganic ion transmembrane transport GO:0098660 234 0.015
gland development GO:0048732 330 0.015
cation homeostasis GO:0055080 212 0.015
mitotic cell cycle GO:0000278 195 0.015
carbohydrate derivative catabolic process GO:1901136 231 0.015
transmission of nerve impulse GO:0019226 76 0.015
response to organonitrogen compound GO:0010243 246 0.015
regulation of protein localization GO:0032880 231 0.015
macromolecule methylation GO:0043414 120 0.015
cellular ion homeostasis GO:0006873 165 0.015
organelle fission GO:0048285 170 0.015
regulation of cell projection organization GO:0031344 206 0.015
wnt signaling pathway GO:0016055 188 0.015
purine ribonucleoside metabolic process GO:0046128 241 0.015
purine nucleotide metabolic process GO:0006163 302 0.015
t cell activation GO:0042110 289 0.015
muscle cell differentiation GO:0042692 261 0.015
regulation of cell cycle process GO:0010564 160 0.015
negative regulation of phosphorylation GO:0042326 166 0.015
cognition GO:0050890 149 0.015
action potential GO:0001508 78 0.015
carboxylic acid biosynthetic process GO:0046394 86 0.015
Human
organic cyclic compound catabolic process GO:1901361 295 0.015
biomineral tissue development GO:0031214 64 0.015
cellular response to peptide hormone stimulus GO:0071375 92 0.015
regulation of cellular catabolic process GO:0031329 242 0.014
methylation GO:0032259 134 0.014
cellular response to organonitrogen compound GO:0071417 145 0.014
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.014
neuromuscular process GO:0050905 99 0.014
regulation of system process GO:0044057 200 0.014
negative regulation of phosphorus metabolic process GO:0010563 184 0.014
protein modification by small protein conjugation or removal GO:0070647 207 0.014
cellular response to cytokine stimulus GO:0071345 189 0.014
regulation of feeding behavior GO:0060259 3 0.014
learning or memory GO:0007611 148 0.014
regulation of anatomical structure size GO:0090066 178 0.014
positive regulation of cell development GO:0010720 237 0.014
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.014
axonogenesis GO:0007409 274 0.014
gluconeogenesis GO:0006094 39 0.014
ribonucleotide metabolic process GO:0009259 291 0.014
cellular divalent inorganic cation homeostasis GO:0072503 127 0.014
regulation of cellular component biogenesis GO:0044087 181 0.014
regulation of hormone levels GO:0010817 211 0.014
regulation of response to wounding GO:1903034 189 0.014
intracellular protein transport GO:0006886 204 0.014
divalent inorganic cation transport GO:0072511 178 0.014
protein processing GO:0016485 163 0.014
histone modification GO:0016570 159 0.014
purine containing compound metabolic process GO:0072521 311 0.014
positive regulation of organelle organization GO:0010638 128 0.013
negative regulation of cellular protein metabolic process GO:0032269 247 0.013
cell substrate adhesion GO:0031589 130 0.013
cellular response to dna damage stimulus GO:0006974 207 0.013
regulation of apoptotic signaling pathway GO:2001233 197 0.013
respiratory tube development GO:0030323 167 0.013
negative regulation of cell development GO:0010721 169 0.013
sequestering of calcium ion GO:0051208 18 0.013
gliogenesis GO:0042063 141 0.013
regulation of body fluid levels GO:0050878 162 0.013
regulation of cell activation GO:0050865 289 0.013
organophosphate catabolic process GO:0046434 232 0.013
homeostasis of number of cells GO:0048872 210 0.013
positive regulation of nervous system development GO:0051962 221 0.013
sulfur compound metabolic process GO:0006790 100 0.013
response to radiation GO:0009314 165 0.013
nucleoside phosphate catabolic process GO:1901292 222 0.013
negative regulation of phosphate metabolic process GO:0045936 184 0.013
synaptic transmission GO:0007268 329 0.013
regulation of homeostatic process GO:0032844 182 0.013
organic hydroxy compound metabolic process GO:1901615 203 0.013
organonitrogen compound catabolic process GO:1901565 264 0.013
striated muscle cell development GO:0055002 125 0.013
chromatin modification GO:0016568 187 0.013
cellular calcium ion homeostasis GO:0006874 119 0.013
cellular response to lipid GO:0071396 145 0.013
myeloid cell differentiation GO:0030099 233 0.013
positive regulation of protein phosphorylation GO:0001934 242 0.013
protein modification by small protein conjugation GO:0032446 187 0.013
bone mineralization GO:0030282 54 0.013
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.012
intrinsic apoptotic signaling pathway GO:0097193 132 0.012
chromatin organization GO:0006325 206 0.012
muscle cell development GO:0055001 133 0.012
regulation of neuron projection development GO:0010975 169 0.012
nucleoside triphosphate metabolic process GO:0009141 230 0.012
sensory organ morphogenesis GO:0090596 242 0.012
negative regulation of neuron death GO:1901215 98 0.012
glycoprotein metabolic process GO:0009100 116 0.012
hormone secretion GO:0046879 128 0.012
cellular response to growth factor stimulus GO:0071363 197 0.012
small molecule catabolic process GO:0044282 71 0.012
developmental maturation GO:0021700 193 0.012
regulation of mitotic cell cycle GO:0007346 126 0.012
sequestering of metal ion GO:0051238 19 0.012
skeletal muscle cell differentiation GO:0035914 66 0.012
rho protein signal transduction GO:0007266 32 0.012
inorganic cation transmembrane transport GO:0098662 207 0.012
production of molecular mediator of immune response GO:0002440 103 0.012
circadian rhythm GO:0007623 114 0.012
cellular response to acid chemical GO:0071229 68 0.012
monosaccharide biosynthetic process GO:0046364 44 0.012
regulation of transferase activity GO:0051338 263 0.012
nuclear division GO:0000280 158 0.012
calcium ion homeostasis GO:0055074 127 0.012
negative regulation of nervous system development GO:0051961 156 0.012
positive regulation of fatty acid oxidation GO:0046321 4 0.012
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.012
ribonucleoside triphosphate metabolic process GO:0009199 220 0.012
actin filament organization GO:0007015 113 0.012
camera type eye development GO:0043010 266 0.012
regulation of fat cell differentiation GO:0045598 81 0.012
tissue homeostasis GO:0001894 115 0.012
synapse organization GO:0050808 125 0.012
generation of precursor metabolites and energy GO:0006091 103 0.012
negative regulation of protein modification process GO:0031400 163 0.012
cellular component assembly involved in morphogenesis GO:0010927 139 0.012
regulation of defense response GO:0031347 233 0.012
posttranscriptional regulation of gene expression GO:0010608 155 0.012
nucleoside catabolic process GO:0009164 206 0.012
regulation of cell cycle phase transition GO:1901987 77 0.012
sensory perception of sound GO:0007605 97 0.012
digestive tract development GO:0048565 190 0.011
regulation of map kinase activity GO:0043405 120 0.011
ribonucleoside catabolic process GO:0042454 206 0.011
rhythmic process GO:0048511 174 0.011
protein localization to organelle GO:0033365 185 0.011
lipid biosynthetic process GO:0008610 179 0.011
actin cytoskeleton organization GO:0030036 220 0.011
renal system development GO:0072001 225 0.011
covalent chromatin modification GO:0016569 163 0.011
nucleotide catabolic process GO:0009166 217 0.011
nucleoside triphosphate catabolic process GO:0009143 205 0.011
alcohol metabolic process GO:0006066 116 0.011
cell division GO:0051301 120 0.011
regulation of neuron death GO:1901214 134 0.011
protein hydroxylation GO:0018126 4 0.011
ribonucleoside metabolic process GO:0009119 245 0.011
regulation of cell migration GO:0030334 219 0.011
appendage development GO:0048736 166 0.011
limb morphogenesis GO:0035108 149 0.011
fertilization GO:0009566 127 0.011
sensory perception of mechanical stimulus GO:0050954 107 0.011
response to inorganic substance GO:0010035 96 0.011
Human
regulation of kinase activity GO:0043549 249 0.011
protein targeting GO:0006605 143 0.011
organophosphate biosynthetic process GO:0090407 122 0.011
maintenance of location GO:0051235 89 0.011
intestinal epithelial structure maintenance GO:0060729 4 0.011
regulation of cytoplasmic transport GO:1903649 112 0.011
regulation of transmembrane transport GO:0034762 128 0.011
placenta development GO:0001890 140 0.011
purine nucleoside triphosphate catabolic process GO:0009146 203 0.011
chondrocyte differentiation GO:0002062 72 0.011
immune response regulating signaling pathway GO:0002764 125 0.011
endocytosis GO:0006897 168 0.011
nucleocytoplasmic transport GO:0006913 139 0.011
regulation of neuron apoptotic process GO:0043523 122 0.011
cellular response to amino acid stimulus GO:0071230 29 0.011
limb development GO:0060173 166 0.011
protein maturation GO:0051604 176 0.011
regulation of lipid metabolic process GO:0019216 118 0.011
regulation of intracellular transport GO:0032386 159 0.011
b cell differentiation GO:0030183 78 0.011
amide transport GO:0042886 138 0.011
defense response to other organism GO:0098542 197 0.011
peptide secretion GO:0002790 114 0.011
cellular response to hormone stimulus GO:0032870 150 0.011
germ cell development GO:0007281 185 0.011
exocytosis GO:0006887 121 0.011
organ growth GO:0035265 117 0.011
regulation of protein kinase activity GO:0045859 232 0.011
dna repair GO:0006281 107 0.011
ribonucleotide catabolic process GO:0009261 208 0.011
protein secretion GO:0009306 111 0.011
lymphocyte mediated immunity GO:0002449 139 0.011
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.010
response to peptide GO:1901652 136 0.010
innate immune response GO:0045087 157 0.010
kidney development GO:0001822 213 0.010
positive regulation of cytokine production GO:0001819 174 0.010
regulation of lymphocyte activation GO:0051249 240 0.010
response to lipopolysaccharide GO:0032496 128 0.010
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 68 0.010
regulation of protein secretion GO:0050708 82 0.010
positive regulation of protein transport GO:0051222 93 0.010
regulation of wnt signaling pathway GO:0030111 123 0.010
negative regulation of protein metabolic process GO:0051248 282 0.010
response to peptide hormone GO:0043434 127 0.010
negative regulation of cellular component organization GO:0051129 194 0.010
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.010
intracellular distribution of mitochondria GO:0048312 1 0.010
endochondral bone morphogenesis GO:0060350 50 0.010
purine ribonucleotide catabolic process GO:0009154 208 0.010
negative regulation of neuron apoptotic process GO:0043524 92 0.010
branched chain amino acid transport GO:0015803 2 0.010
positive regulation of proteolysis GO:0045862 85 0.010
meiotic nuclear division GO:0007126 115 0.010
peptide transport GO:0015833 133 0.010
central nervous system neuron differentiation GO:0021953 162 0.010
blood vessel morphogenesis GO:0048514 285 0.010
activation of immune response GO:0002253 138 0.010
nuclear transport GO:0051169 139 0.010

Pycr1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.034
musculoskeletal system disease DOID:17 0 0.034
connective tissue disease DOID:65 0 0.027
nervous system disease DOID:863 0 0.024
bone disease DOID:0080001 0 0.023
disease of metabolism DOID:0014667 0 0.014
bone development disease DOID:0080006 0 0.013
disease of cellular proliferation DOID:14566 0 0.011
inherited metabolic disorder DOID:655 0 0.010