|
|
extracellular structure organization
|
GO:0043062 |
148 |
0.221
|
|
|
|
extracellular matrix organization
|
GO:0030198 |
147 |
0.106
|
|
|
|
bone development
|
GO:0060348 |
120 |
0.088
|
|
|
|
protein hydroxylation
|
GO:0018126 |
4 |
0.070
|
|
|
|
response to oxidative stress
|
GO:0006979 |
123 |
0.064
|
|
|
|
cell adhesion
|
GO:0007155 |
329 |
0.060
|
|
|
|
ossification
|
GO:0001503 |
216 |
0.060
|
|
|
|
skeletal system development
|
GO:0001501 |
356 |
0.059
|
|
|
|
macromolecule catabolic process
|
GO:0009057 |
281 |
0.059
|
|
|
|
cellular response to amino acid stimulus
|
GO:0071230 |
29 |
0.057
|
|
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
145 |
0.049
|
|
|
|
nitrogen compound transport
|
GO:0071705 |
271 |
0.049
|
|
|
|
glycoprotein metabolic process
|
GO:0009100 |
116 |
0.047
|
|
|
|
endochondral bone morphogenesis
|
GO:0060350 |
50 |
0.044
|
|
|
|
cartilage development
|
GO:0051216 |
140 |
0.044
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
306 |
0.043
|
|
|
|
regulation of cell adhesion
|
GO:0030155 |
154 |
0.042
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
246 |
0.042
|
|
|
|
chondrocyte differentiation
|
GO:0002062 |
72 |
0.042
|
|
|
|
regulation of hormone levels
|
GO:0010817 |
211 |
0.041
|
|
|
|
connective tissue development
|
GO:0061448 |
179 |
0.040
|
|
|
|
oxidation reduction process
|
GO:0055114 |
342 |
0.039
|
|
|
|
antibacterial peptide secretion
|
GO:0002779 |
1 |
0.037
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
103 |
0.037
|
|
|
|
cellular response to acid chemical
|
GO:0071229 |
68 |
0.036
|
|
|
|
monocarboxylic acid metabolic process
|
GO:0032787 |
191 |
0.036
|
|
|
|
digestive tract development
|
GO:0048565 |
190 |
0.033
|
|
|
|
spermatogenesis
|
GO:0007283 |
284 |
0.033
|
|
|
|
multicellular organismal homeostasis
|
GO:0048871 |
164 |
0.032
|
|
|
|
tissue homeostasis
|
GO:0001894 |
115 |
0.032
|
|
|
|
fat cell differentiation
|
GO:0045444 |
160 |
0.032
|
|
|
|
peptidyl proline hydroxylation
|
GO:0019511 |
3 |
0.031
|
|
|
|
cellular response to oxidative stress
|
GO:0034599 |
76 |
0.030
|
|
|
|
male gamete generation
|
GO:0048232 |
285 |
0.030
|
|
|
|
metal ion homeostasis
|
GO:0055065 |
189 |
0.030
|
|
|
|
circulatory system process
|
GO:0003013 |
197 |
0.028
|
|
|
|
carbohydrate derivative biosynthetic process
|
GO:1901137 |
183 |
0.028
|
|
|
|
organonitrogen compound biosynthetic process
|
GO:1901566 |
192 |
0.028
|
|
|
|
bone morphogenesis
|
GO:0060349 |
78 |
0.028
|
|
|
|
membrane organization
|
GO:0061024 |
245 |
0.027
|
|
|
|
antibacterial peptide production
|
GO:0002778 |
2 |
0.026
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
198 |
0.025
|
|
|
|
regulation of system process
|
GO:0044057 |
200 |
0.024
|
|
|
|
antibacterial peptide biosynthetic process
|
GO:0002780 |
2 |
0.024
|
|
|
|
blood circulation
|
GO:0008015 |
195 |
0.023
|
|
|
|
antimicrobial peptide secretion
|
GO:0002776 |
1 |
0.023
|
|
|
|
response to acid chemical
|
GO:0001101 |
111 |
0.023
|
|
|
|
generation of precursor metabolites and energy
|
GO:0006091 |
103 |
0.023
|
|
|
|
endomembrane system organization
|
GO:0010256 |
147 |
0.023
|
Fly |
|
|
innate immune response
|
GO:0045087 |
157 |
0.022
|
|
|
|
sensory perception of sound
|
GO:0007605 |
97 |
0.022
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
77 |
0.022
|
|
|
|
protein catabolic process
|
GO:0030163 |
221 |
0.021
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
66 |
0.021
|
|
|
|
carbohydrate metabolic process
|
GO:0005975 |
230 |
0.021
|
Mouse |
|
|
renal system development
|
GO:0072001 |
225 |
0.021
|
|
|
|
negative regulation of apoptotic signaling pathway
|
GO:2001234 |
104 |
0.021
|
|
|
|
cell substrate adhesion
|
GO:0031589 |
130 |
0.021
|
|
|
|
embryonic skeletal system development
|
GO:0048706 |
120 |
0.021
|
|
|
|
skeletal system morphogenesis
|
GO:0048705 |
203 |
0.021
|
|
|
|
response to amino acid
|
GO:0043200 |
37 |
0.021
|
|
|
|
regulation of fat cell differentiation
|
GO:0045598 |
81 |
0.020
|
|
|
|
sensory perception
|
GO:0007600 |
245 |
0.020
|
|
|
|
cellular modified amino acid metabolic process
|
GO:0006575 |
63 |
0.020
|
|
|
|
regulation of cell substrate adhesion
|
GO:0010810 |
73 |
0.020
|
|
|
|
anatomical structure homeostasis
|
GO:0060249 |
145 |
0.020
|
|
|
|
nucleoside phosphate metabolic process
|
GO:0006753 |
338 |
0.020
|
|
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
84 |
0.019
|
|
|
|
multicellular organismal catabolic process
|
GO:0044243 |
7 |
0.019
|
|
|
|
sensory perception of mechanical stimulus
|
GO:0050954 |
107 |
0.019
|
|
|
|
positive regulation of fatty acid oxidation
|
GO:0046321 |
4 |
0.019
|
|
|
|
amide transport
|
GO:0042886 |
138 |
0.019
|
|
|
|
head morphogenesis
|
GO:0060323 |
34 |
0.019
|
|
|
|
regulation of defense response
|
GO:0031347 |
233 |
0.019
|
|
|
|
antimicrobial peptide production
|
GO:0002775 |
2 |
0.018
|
|
|
|
cellular response to hormone stimulus
|
GO:0032870 |
150 |
0.018
|
|
|
|
regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090092 |
112 |
0.018
|
|
|
|
negative regulation of macrophage chemotaxis
|
GO:0010760 |
1 |
0.018
|
|
|
|
cellular carbohydrate metabolic process
|
GO:0044262 |
119 |
0.018
|
|
|
|
negative regulation of immune system process
|
GO:0002683 |
209 |
0.018
|
|
|
|
nucleobase containing small molecule metabolic process
|
GO:0055086 |
352 |
0.018
|
|
|
|
biomineral tissue development
|
GO:0031214 |
64 |
0.018
|
|
|
|
transmission of nerve impulse
|
GO:0019226 |
76 |
0.018
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
164 |
0.018
|
|
|
|
cation transmembrane transport
|
GO:0098655 |
266 |
0.018
|
|
|
|
protein heterooligomerization
|
GO:0051291 |
14 |
0.018
|
|
|
|
regulation of removal of superoxide radicals
|
GO:2000121 |
4 |
0.017
|
|
|
|
regulation of reactive oxygen species metabolic process
|
GO:2000377 |
40 |
0.017
|
|
|
|
antimicrobial peptide biosynthetic process
|
GO:0002777 |
2 |
0.017
|
|
|
|
protein trimerization
|
GO:0070206 |
13 |
0.017
|
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
126 |
0.017
|
|
|
|
protein oligomerization
|
GO:0051259 |
67 |
0.017
|
|
|
|
fibril organization
|
GO:0097435 |
2 |
0.017
|
|
|
|
cellular divalent inorganic cation homeostasis
|
GO:0072503 |
127 |
0.017
|
|
|
|
cellular response to abiotic stimulus
|
GO:0071214 |
56 |
0.016
|
|
|
|
peptide secretion
|
GO:0002790 |
114 |
0.016
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
167 |
0.016
|
|
|
|
rho protein signal transduction
|
GO:0007266 |
32 |
0.016
|
|
|
|
respiratory system development
|
GO:0060541 |
190 |
0.016
|
|
|
|
hormone secretion
|
GO:0046879 |
128 |
0.016
|
|
|
|
cellular glucan metabolic process
|
GO:0006073 |
32 |
0.016
|
|
|
|
nucleotide metabolic process
|
GO:0009117 |
332 |
0.016
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
197 |
0.016
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
97 |
0.016
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
296 |
0.016
|
|
|
|
cartilage development involved in endochondral bone morphogenesis
|
GO:0060351 |
24 |
0.016
|
|
|
|
digestive system development
|
GO:0055123 |
200 |
0.015
|
|
|
|
limb morphogenesis
|
GO:0035108 |
149 |
0.015
|
|
|
|
protein maturation
|
GO:0051604 |
176 |
0.015
|
|
|
|
reactive nitrogen species metabolic process
|
GO:2001057 |
0 |
0.015
|
|
|
|
cellular polysaccharide metabolic process
|
GO:0044264 |
38 |
0.015
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
224 |
0.015
|
|
|
|
lung development
|
GO:0030324 |
164 |
0.015
|
|
|
|
carbohydrate biosynthetic process
|
GO:0016051 |
74 |
0.015
|
Mouse |
|
|
protein heterotrimerization
|
GO:0070208 |
8 |
0.015
|
|
|
|
ribose phosphate metabolic process
|
GO:0019693 |
291 |
0.015
|
|
|
|
regulation of blood circulation
|
GO:1903522 |
93 |
0.015
|
|
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
206 |
0.014
|
|
|
|
multicellular organismal signaling
|
GO:0035637 |
91 |
0.014
|
|
|
|
trabecula formation
|
GO:0060343 |
24 |
0.014
|
|
|
|
inorganic ion transmembrane transport
|
GO:0098660 |
234 |
0.014
|
|
|
|
replacement ossification
|
GO:0036075 |
26 |
0.014
|
|
|
|
purine containing compound metabolic process
|
GO:0072521 |
311 |
0.014
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
181 |
0.014
|
|
|
|
organophosphate biosynthetic process
|
GO:0090407 |
122 |
0.014
|
|
|
|
negative regulation of cell development
|
GO:0010721 |
169 |
0.014
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
218 |
0.014
|
|
|
|
negative regulation of cellular response to growth factor stimulus
|
GO:0090288 |
46 |
0.014
|
|
|
|
positive regulation of adiponectin secretion
|
GO:0070165 |
1 |
0.014
|
|
|
|
acetylcholine transport
|
GO:0015870 |
2 |
0.014
|
|
|
|
regulation of secretion
|
GO:0051046 |
274 |
0.014
|
|
|
|
cellular protein catabolic process
|
GO:0044257 |
155 |
0.013
|
|
|
|
trabecula morphogenesis
|
GO:0061383 |
40 |
0.013
|
|
|
|
immune effector process
|
GO:0002252 |
321 |
0.013
|
|
|
|
positive regulation of secretion by cell
|
GO:1903532 |
114 |
0.013
|
|
|
|
carbohydrate derivative catabolic process
|
GO:1901136 |
231 |
0.013
|
|
|
|
peptide metabolic process
|
GO:0006518 |
46 |
0.013
|
|
|
|
positive regulation of cellular component biogenesis
|
GO:0044089 |
94 |
0.013
|
|
|
|
protein processing
|
GO:0016485 |
163 |
0.013
|
|
|
|
purine ribonucleotide metabolic process
|
GO:0009150 |
290 |
0.013
|
|
|
|
divalent inorganic cation transport
|
GO:0072511 |
178 |
0.013
|
|
|
|
regulation of cell motility
|
GO:2000145 |
236 |
0.013
|
|
|
|
peptidyl amino acid modification
|
GO:0018193 |
336 |
0.013
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
84 |
0.013
|
|
|
|
gastrulation
|
GO:0007369 |
116 |
0.013
|
|
|
|
phagosome maturation
|
GO:0090382 |
4 |
0.013
|
|
|
|
response to inorganic substance
|
GO:0010035 |
96 |
0.013
|
|
|
|
extrinsic apoptotic signaling pathway in absence of ligand
|
GO:0097192 |
55 |
0.012
|
|
|
|
ear development
|
GO:0043583 |
200 |
0.012
|
|
|
|
positive regulation of reactive oxygen species biosynthetic process
|
GO:1903428 |
2 |
0.012
|
|
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
194 |
0.012
|
|
|
|
plasma membrane organization
|
GO:0007009 |
90 |
0.012
|
|
|
|
signal transduction in absence of ligand
|
GO:0038034 |
55 |
0.012
|
|
|
|
insulin processing
|
GO:0030070 |
2 |
0.012
|
|
|
|
organelle assembly
|
GO:0070925 |
177 |
0.012
|
|
|
|
polysaccharide metabolic process
|
GO:0005976 |
39 |
0.012
|
|
|
|
glycosaminoglycan metabolic process
|
GO:0030203 |
34 |
0.012
|
|
|
|
regulation of reactive oxygen species biosynthetic process
|
GO:1903426 |
2 |
0.012
|
|
|
|
chromatin organization
|
GO:0006325 |
206 |
0.012
|
|
|
|
growth plate cartilage development
|
GO:0003417 |
14 |
0.012
|
|
|
|
positive regulation of cell adhesion
|
GO:0045785 |
80 |
0.012
|
|
|
|
synapse organization
|
GO:0050808 |
125 |
0.012
|
|
|
|
response to extracellular stimulus
|
GO:0009991 |
127 |
0.012
|
|
|
|
bone trabecula formation
|
GO:0060346 |
9 |
0.012
|
|
|
|
divalent metal ion transport
|
GO:0070838 |
172 |
0.012
|
|
|
|
energy derivation by oxidation of organic compounds
|
GO:0015980 |
77 |
0.012
|
|
|
|
regulation of adiponectin secretion
|
GO:0070163 |
2 |
0.012
|
|
|
|
response to decreased oxygen levels
|
GO:0036293 |
59 |
0.012
|
|
|
|
activation of immune response
|
GO:0002253 |
138 |
0.012
|
|
|
|
phagolysosome assembly
|
GO:0001845 |
3 |
0.011
|
|
|
|
regulation of secretion by cell
|
GO:1903530 |
249 |
0.011
|
|
|
|
regulation of organelle organization
|
GO:0033043 |
289 |
0.011
|
|
|
|
cellular response to external stimulus
|
GO:0071496 |
88 |
0.011
|
|
|
|
cation transport
|
GO:0006812 |
399 |
0.011
|
|
|
|
regulation of synaptic growth at neuromuscular junction
|
GO:0008582 |
4 |
0.011
|
|
|
|
covalent chromatin modification
|
GO:0016569 |
163 |
0.011
|
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
215 |
0.011
|
|
|
|
cation homeostasis
|
GO:0055080 |
212 |
0.011
|
|
|
|
developmental maturation
|
GO:0021700 |
193 |
0.011
|
|
|
|
positive regulation of defense response
|
GO:0031349 |
124 |
0.011
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
268 |
0.011
|
|
|
|
sulfur compound metabolic process
|
GO:0006790 |
100 |
0.011
|
|
|
|
glucose import
|
GO:0046323 |
32 |
0.011
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
217 |
0.011
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
220 |
0.011
|
|
|
|
reactive oxygen species biosynthetic process
|
GO:1903409 |
8 |
0.011
|
|
|
|
smoothened signaling pathway
|
GO:0007224 |
105 |
0.011
|
|
|
|
regulation of glucose metabolic process
|
GO:0010906 |
60 |
0.011
|
|
|
|
purine nucleotide metabolic process
|
GO:0006163 |
302 |
0.011
|
|
|
|
dna metabolic process
|
GO:0006259 |
303 |
0.011
|
|
|
|
negative regulation of dna replication
|
GO:0008156 |
4 |
0.011
|
|
|
|
intracellular protein transport
|
GO:0006886 |
204 |
0.011
|
|
|
|
positive regulation of innate immune response
|
GO:0045089 |
80 |
0.011
|
|
|
|
regulation of ossification
|
GO:0030278 |
112 |
0.011
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
184 |
0.011
|
|
|
|
glucan metabolic process
|
GO:0044042 |
32 |
0.011
|
|
|
|
peptide transport
|
GO:0015833 |
133 |
0.011
|
|
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
155 |
0.011
|
|
|
|
negative regulation of nervous system development
|
GO:0051961 |
156 |
0.011
|
|
|
|
cellular calcium ion homeostasis
|
GO:0006874 |
119 |
0.011
|
|
|
|
pallium development
|
GO:0021543 |
120 |
0.011
|
|
|
|
hexose biosynthetic process
|
GO:0019319 |
39 |
0.011
|
|
|
|
organ growth
|
GO:0035265 |
117 |
0.011
|
|
|
|
aminoglycan metabolic process
|
GO:0006022 |
34 |
0.011
|
|
|
|
lateral inhibition
|
GO:0046331 |
1 |
0.011
|
|
|
|
inorganic cation transmembrane transport
|
GO:0098662 |
207 |
0.010
|
|
|
|
glycogen metabolic process
|
GO:0005977 |
32 |
0.010
|
|
|
|
stem cell differentiation
|
GO:0048863 |
268 |
0.010
|
|
|
|
telencephalon development
|
GO:0021537 |
186 |
0.010
|
|
|
|
regulation of anatomical structure size
|
GO:0090066 |
178 |
0.010
|
|
|
|
mitochondrion distribution
|
GO:0048311 |
4 |
0.010
|
|
|
|
transforming growth factor beta receptor signaling pathway
|
GO:0007179 |
71 |
0.010
|
|
|
|
regulation of cell migration
|
GO:0030334 |
219 |
0.010
|
|
|
|
response to increased oxygen levels
|
GO:0036296 |
2 |
0.010
|
|
|
|
cell matrix adhesion
|
GO:0007160 |
68 |
0.010
|
|
|
|
cellular amide metabolic process
|
GO:0043603 |
58 |
0.010
|
|
|
|
cellular ion homeostasis
|
GO:0006873 |
165 |
0.010
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.010
|
|
|
|
cellular response to lipid
|
GO:0071396 |
145 |
0.010
|
|
|
|
regulation of cellular response to oxidative stress
|
GO:1900407 |
19 |
0.010
|
|
|
|
collagen fibril organization
|
GO:0030199 |
32 |
0.010
|
|
|
|
appendage morphogenesis
|
GO:0035107 |
149 |
0.010
|
|
|
|
anatomical structure maturation
|
GO:0071695 |
49 |
0.010
|
|