Mus musculus

65 known processes

Nrxn2

neurexin II

(Aliases: 6430591O13Rik,mKIAA0921)

Nrxn2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
vitamin transport GO:0051180 10 1.000
Fly
regulation of alpha amino 3 hydroxy 5 methyl 4 isoxazole propionate selective glutamate receptor activity GO:2000311 11 0.995
Mouse
regulation of synaptic vesicle recycling GO:1903421 2 0.994
Fly
gephyrin clustering GO:0097116 3 0.992
positive regulation of synaptic vesicle recycling GO:1903423 1 0.988
Fly
cerebellar granular layer development GO:0021681 13 0.984
Mouse
heterophilic cell cell adhesion via plasma membrane cell adhesion molecules GO:0007157 20 0.941
Mouse
regulation of synaptic vesicle endocytosis GO:1900242 2 0.940
Fly
calcium dependent cell cell adhesion via plasma membrane cell adhesion molecules GO:0016339 9 0.922
Mouse
positive regulation of synaptic vesicle endocytosis GO:1900244 1 0.895
Fly
receptor localization to synapse GO:0097120 4 0.884
Mouse
postsynaptic density protein 95 clustering GO:0097119 6 0.859
regulation of terminal button organization GO:2000331 1 0.846
Fly
negative regulation of filopodium assembly GO:0051490 2 0.838
Mouse
regulation of synaptic vesicle transport GO:1902803 13 0.808
Fly
regulation of n methyl d aspartate selective glutamate receptor activity GO:2000310 10 0.799
Mouse
social behavior GO:0035176 21 0.794
Human
cerebellar granule cell differentiation GO:0021707 9 0.771
Mouse
regulation of grooming behavior GO:2000821 4 0.730
Mouse
regulation of glutamate receptor signaling pathway GO:1900449 16 0.730
Mouse
positive regulation of synaptic vesicle transport GO:1902805 1 0.670
Fly
regulation of membrane potential GO:0042391 192 0.605
Mouse
membrane depolarization GO:0051899 64 0.576
Mouse
vesicle localization GO:0051648 86 0.547
Mouse Fly
terminal button organization GO:0072553 3 0.539
Fly
regulation of excitatory postsynaptic membrane potential GO:0060079 41 0.533
Mouse
auditory behavior GO:0031223 3 0.530
Human
membrane biogenesis GO:0044091 12 0.522
postsynaptic membrane organization GO:0001941 18 0.516
protein localization to membrane GO:0072657 108 0.498
regulation of synaptic transmission glutamatergic GO:0051966 19 0.493
Mouse
cerebellum morphogenesis GO:0021587 42 0.489
Mouse
positive regulation of synaptic transmission glutamatergic GO:0051968 8 0.478
Mouse
neurotransmitter gated ion channel clustering GO:0072578 6 0.462
Mouse
establishment of vesicle localization GO:0051650 81 0.458
Fly
positive regulation of membrane potential GO:0045838 15 0.440
Mouse
synaptic vesicle localization GO:0097479 59 0.431
Mouse Fly
regulation of postsynaptic membrane potential GO:0060078 48 0.425
Mouse
positive regulation of establishment of protein localization to plasma membrane GO:0090004 7 0.417
Mouse
ion transmembrane transport GO:0034220 361 0.417
membrane assembly GO:0071709 12 0.416
establishment of synaptic vesicle localization GO:0097480 57 0.414
Fly
central nervous system neuron differentiation GO:0021953 162 0.412
Mouse
metencephalon development GO:0022037 89 0.406
Mouse
cerebellar cortex formation GO:0021697 22 0.393
Mouse
positive regulation of excitatory postsynaptic membrane potential GO:2000463 14 0.383
Mouse
cell adhesion GO:0007155 329 0.376
Mouse
regulation of establishment of protein localization to plasma membrane GO:0090003 12 0.375
Mouse
neuron cell cell adhesion GO:0007158 6 0.374
Mouse
synaptic vesicle recycling GO:0036465 19 0.363
Fly
presynaptic membrane assembly GO:0097105 7 0.360
Mouse Fly
neuromuscular process controlling balance GO:0050885 59 0.350
Mouse
presynaptic membrane organization GO:0097090 8 0.349
Mouse Fly
intraspecies interaction between organisms GO:0051703 21 0.332
Human
neurotransmitter transport GO:0006836 76 0.329
isoprenoid transport GO:0046864 3 0.328
Fly
protein localization to synapse GO:0035418 11 0.317
Mouse
hindbrain morphogenesis GO:0021575 46 0.303
Mouse
cerebellar cortex morphogenesis GO:0021696 32 0.303
Mouse
establishment of protein localization to membrane GO:0090150 54 0.300
Mouse
regulation of receptor activity GO:0010469 41 0.297
Mouse
glutamate receptor signaling pathway GO:0007215 35 0.293
Mouse
neurotransmitter secretion GO:0007269 62 0.290
n methyl d aspartate receptor clustering GO:0097114 3 0.286
Mouse
cerebellum development GO:0021549 77 0.277
Mouse
associative learning GO:0008306 61 0.275
Fly
synapse maturation GO:0060074 14 0.264
Mouse
positive regulation of protein localization to plasma membrane GO:1903078 7 0.259
Mouse
cell cell adhesion via plasma membrane adhesion molecules GO:0098742 40 0.258
Mouse
regulation of neurotransmitter levels GO:0001505 87 0.257
regulation of establishment of protein localization GO:0070201 181 0.256
Mouse
observational learning GO:0098597 1 0.252
Human
synaptic vesicle transport GO:0048489 57 0.251
Fly
grooming behavior GO:0007625 16 0.244
Mouse
cellular response to carbohydrate stimulus GO:0071322 50 0.240
Mouse
membrane organization GO:0061024 245 0.238
cell cell adhesion GO:0098609 41 0.234
Mouse
regulation of synapse maturation GO:0090128 9 0.232
Mouse
neuron maturation GO:0042551 29 0.231
Mouse
regulation of secretion GO:0051046 274 0.226
Mouse
hindbrain development GO:0030902 128 0.225
Mouse
regulation of protein localization to plasma membrane GO:1903076 13 0.217
Mouse
regulation of hormone levels GO:0010817 211 0.215
Mouse
synaptic vesicle endocytosis GO:0048488 19 0.214
Fly
synapse organization GO:0050808 125 0.212
cerebellar cortex development GO:0021695 48 0.209
Mouse
regulation of ion transport GO:0043269 215 0.206
Mouse
negative regulation of cell projection organization GO:0031345 56 0.198
Mouse
positive regulation of synapse assembly GO:0051965 18 0.196
Mouse
cellular homeostasis GO:0019725 240 0.193
Mouse
cerebellar granular layer formation GO:0021684 9 0.190
Mouse
single organism cell adhesion GO:0098602 156 0.183
Mouse
regulation of secretion by cell GO:1903530 249 0.181
Mouse
regulation of protein localization GO:0032880 231 0.170
Mouse
hormone secretion GO:0046879 128 0.170
Mouse
regulation of transmembrane transport GO:0034762 128 0.168
Mouse
learned vocalization behavior or vocal learning GO:0098598 1 0.167
Human
neuron neuron synaptic transmission GO:0007270 69 0.166
Mouse
postsynaptic membrane assembly GO:0097104 6 0.165
cellular response to glucose stimulus GO:0071333 45 0.165
Mouse
protein localization to plasma membrane GO:0072659 57 0.165
Mouse
establishment of organelle localization GO:0051656 122 0.162
Fly
organelle localization GO:0051640 179 0.161
Mouse Fly
vocal learning GO:0042297 1 0.158
Human
single organismal cell cell adhesion GO:0016337 131 0.158
Mouse
prepulse inhibition GO:0060134 10 0.157
Mouse
regulation of ion transmembrane transport GO:0034765 119 0.156
Mouse
filopodium assembly GO:0046847 19 0.155
Mouse
regulation of cellular component biogenesis GO:0044087 181 0.155
Mouse
amide transport GO:0042886 138 0.152
Mouse
regulation of homeostatic process GO:0032844 182 0.151
Mouse
regulation of endocytosis GO:0030100 69 0.149
Fly
regulation of peptide hormone secretion GO:0090276 75 0.146
Mouse
neuromuscular process GO:0050905 99 0.146
Mouse
carbohydrate homeostasis GO:0033500 128 0.145
Mouse
regulation of cell projection organization GO:0031344 206 0.143
Mouse
glucose homeostasis GO:0042593 128 0.141
Mouse
regulation of hormone secretion GO:0046883 88 0.135
Mouse
endocytosis GO:0006897 168 0.135
Fly
regulation of ion transmembrane transporter activity GO:0032412 54 0.130
Mouse
establishment of protein localization to plasma membrane GO:0090002 34 0.128
Mouse
multi organism behavior GO:0051705 62 0.127
Human
positive regulation of nervous system development GO:0051962 221 0.127
Mouse
positive regulation of cellular component biogenesis GO:0044089 94 0.124
Mouse
insulin secretion involved in cellular response to glucose stimulus GO:0035773 36 0.123
Mouse
negative regulation of cellular component organization GO:0051129 194 0.122
Mouse
regulation of peptide transport GO:0090087 91 0.122
Mouse
lipid transport GO:0006869 98 0.120
Fly
synaptic growth at neuromuscular junction GO:0051124 6 0.118
Fly
positive regulation of endocytosis GO:0045807 42 0.117
Fly
adult behavior GO:0030534 135 0.117
Human Mouse
regulation of cell projection assembly GO:0060491 38 0.116
Mouse
regulation of insulin secretion involved in cellular response to glucose stimulus GO:0061178 31 0.115
Mouse
plasma membrane organization GO:0007009 90 0.112
Mouse
insulin secretion GO:0030073 89 0.108
Mouse
regulation of filopodium assembly GO:0051489 13 0.100
Mouse
response to monosaccharide GO:0034284 67 0.098
Mouse
synaptic transmission glutamatergic GO:0035249 36 0.098
Mouse
cell differentiation in hindbrain GO:0021533 24 0.095
Mouse
cellular response to hexose stimulus GO:0071331 47 0.093
Mouse
peptide hormone secretion GO:0030072 109 0.093
Mouse
endomembrane system organization GO:0010256 147 0.092
Mouse
lipid localization GO:0010876 126 0.091
Fly
learning GO:0007612 98 0.090
Human Mouse Fly
peptide secretion GO:0002790 114 0.087
Mouse
peptide transport GO:0015833 133 0.083
Mouse
guanylate kinase associated protein clustering GO:0097117 2 0.082
Mouse
synapse assembly GO:0007416 56 0.082
positive regulation of synapse maturation GO:0090129 7 0.081
Mouse
cellular glucose homeostasis GO:0001678 52 0.081
Mouse
cell maturation GO:0048469 127 0.079
Mouse
regulation of peptide secretion GO:0002791 77 0.077
Mouse
neuromuscular synaptic transmission GO:0007274 16 0.076
Fly
cognition GO:0050890 149 0.068
Human Mouse Fly
synaptic transmission GO:0007268 329 0.060
regulation of synapse assembly GO:0051963 29 0.057
Mouse
regulation of transporter activity GO:0032409 57 0.056
Mouse
transmembrane transport GO:0055085 412 0.054
regulation of cellular ketone metabolic process GO:0010565 66 0.054
regulation of cellular amino acid metabolic process GO:0006521 5 0.053
cellular response to monosaccharide stimulus GO:0071326 47 0.053
Mouse
sensory perception GO:0007600 245 0.050
cellular chemical homeostasis GO:0055082 215 0.048
Mouse
vocalization behavior GO:0071625 7 0.046
Human
cellular amine metabolic process GO:0044106 44 0.043
fat cell differentiation GO:0045444 160 0.039
negative regulation of intracellular signal transduction GO:1902532 167 0.036
ribonucleotide metabolic process GO:0009259 291 0.035
cellular amino acid metabolic process GO:0006520 103 0.035
amine metabolic process GO:0009308 45 0.034
nitrogen compound transport GO:0071705 271 0.034
Mouse
synaptic vesicle clustering GO:0097091 3 0.034
Mouse
regulation of protein serine threonine kinase activity GO:0071900 157 0.034
immune effector process GO:0002252 321 0.032
cation transport GO:0006812 399 0.032
regulation of mapk cascade GO:0043408 248 0.030
retina development in camera type eye GO:0060041 119 0.029
renal system development GO:0072001 225 0.029
nucleobase containing small molecule metabolic process GO:0055086 352 0.029
regulation of actin filament based process GO:0032970 99 0.029
cellular ketone metabolic process GO:0042180 84 0.028
response to radiation GO:0009314 165 0.028
regulation of cellular component size GO:0032535 121 0.027
apoptotic signaling pathway GO:0097190 306 0.027
positive regulation of protein phosphorylation GO:0001934 242 0.027
purine nucleoside catabolic process GO:0006152 205 0.027
actin cytoskeleton organization GO:0030036 220 0.026
purine ribonucleotide metabolic process GO:0009150 290 0.025
nucleoside phosphate catabolic process GO:1901292 222 0.025
protein catabolic process GO:0030163 221 0.025
purine nucleotide metabolic process GO:0006163 302 0.025
ras protein signal transduction GO:0007265 77 0.024
regulation of system process GO:0044057 200 0.023
regulation of protein kinase activity GO:0045859 232 0.023
heterocycle catabolic process GO:0046700 280 0.023
regulation of cell migration GO:0030334 219 0.023
purine ribonucleoside catabolic process GO:0046130 205 0.022
regulation of fat cell differentiation GO:0045598 81 0.022
negative regulation of protein metabolic process GO:0051248 282 0.022
purine containing compound metabolic process GO:0072521 311 0.022
axonogenesis GO:0007409 274 0.022
Zebrafish
negative regulation of protein modification process GO:0031400 163 0.022
nucleotide catabolic process GO:0009166 217 0.022
regulation of organelle organization GO:0033043 289 0.021
aromatic compound catabolic process GO:0019439 286 0.021
camera type eye development GO:0043010 266 0.021
purine nucleoside metabolic process GO:0042278 241 0.021
regulation of neuron apoptotic process GO:0043523 122 0.021
negative regulation of protein phosphorylation GO:0001933 126 0.021
macromolecule catabolic process GO:0009057 281 0.021
guanosine containing compound catabolic process GO:1901069 144 0.021
negative regulation of phosphorus metabolic process GO:0010563 184 0.020
purine containing compound catabolic process GO:0072523 213 0.020
purine nucleotide catabolic process GO:0006195 211 0.020
dendrite development GO:0016358 115 0.020
glycosyl compound metabolic process GO:1901657 246 0.020
carbohydrate derivative catabolic process GO:1901136 231 0.020
small gtpase mediated signal transduction GO:0007264 97 0.020
regulation of anatomical structure size GO:0090066 178 0.020
rhythmic process GO:0048511 174 0.020
organophosphate catabolic process GO:0046434 232 0.020
ribonucleoside catabolic process GO:0042454 206 0.020
regulation of cell motility GO:2000145 236 0.020
kidney development GO:0001822 213 0.019
nucleoside metabolic process GO:0009116 246 0.019
positive regulation of cell death GO:0010942 224 0.019
positive regulation of cell development GO:0010720 237 0.019
lymphocyte mediated immunity GO:0002449 139 0.019
purine nucleoside triphosphate catabolic process GO:0009146 203 0.019
negative regulation of kinase activity GO:0033673 81 0.019
nucleoside phosphate metabolic process GO:0006753 338 0.019
ribonucleoside metabolic process GO:0009119 245 0.018
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.018
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.018
rho protein signal transduction GO:0007266 32 0.018
regulation of cytoskeleton organization GO:0051493 122 0.018
ribonucleoside triphosphate metabolic process GO:0009199 220 0.018
regulation of protein catabolic process GO:0042176 108 0.018
organonitrogen compound catabolic process GO:1901565 264 0.018
positive regulation of cellular amine metabolic process GO:0033240 5 0.018
regulation of cell adhesion GO:0030155 154 0.017
ribonucleotide catabolic process GO:0009261 208 0.017
nucleoside triphosphate metabolic process GO:0009141 230 0.017
positive regulation of programmed cell death GO:0043068 218 0.017
alpha amino 3 hydroxy 5 methyl 4 isoxazole propionate selective glutamate receptor clustering GO:0097113 3 0.017
homeostasis of number of cells GO:0048872 210 0.017
positive regulation of neuron projection development GO:0010976 79 0.017
ribonucleoside triphosphate catabolic process GO:0009203 199 0.017
compound eye development GO:0048749 1 0.017
peptidyl amino acid modification GO:0018193 336 0.017
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.017
epithelial tube morphogenesis GO:0060562 303 0.017
cation transmembrane transport GO:0098655 266 0.017
cation homeostasis GO:0055080 212 0.017
cell type specific apoptotic process GO:0097285 268 0.017
positive regulation of protein modification process GO:0031401 299 0.017
nucleoside catabolic process GO:0009164 206 0.017
rap protein signal transduction GO:0032486 3 0.017
regulation of glucose transport GO:0010827 32 0.016
cellular nitrogen compound catabolic process GO:0044270 280 0.016
purine ribonucleoside metabolic process GO:0046128 241 0.016
stem cell differentiation GO:0048863 268 0.016
negative regulation of phosphorylation GO:0042326 166 0.016
positive regulation of kinase activity GO:0033674 155 0.016
locomotory behavior GO:0007626 195 0.016
carbohydrate metabolic process GO:0005975 230 0.016
response to organonitrogen compound GO:0010243 246 0.016
regulation of cellular catabolic process GO:0031329 242 0.016
regulation of proteolysis GO:0030162 164 0.015
ribose phosphate metabolic process GO:0019693 291 0.015
regulation of hydrolase activity GO:0051336 246 0.015
regulation of cellular amine metabolic process GO:0033238 20 0.015
negative regulation of cellular amine metabolic process GO:0033239 1 0.015
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.015
regulation of lipid metabolic process GO:0019216 118 0.015
response to acid chemical GO:0001101 111 0.015
negative regulation of cellular protein metabolic process GO:0032269 247 0.015
regulation of vesicle mediated transport GO:0060627 139 0.015
Fly
sensory organ morphogenesis GO:0090596 242 0.015
reactive oxygen species metabolic process GO:0072593 84 0.015
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.014
posttranscriptional regulation of gene expression GO:0010608 155 0.014
chemotaxis GO:0006935 247 0.014
Zebrafish
cell growth GO:0016049 130 0.014
positive regulation of apoptotic process GO:0043065 217 0.014
organic hydroxy compound metabolic process GO:1901615 203 0.014
intracellular protein transport GO:0006886 204 0.014
negative regulation of molecular function GO:0044092 258 0.014
skeletal system development GO:0001501 356 0.014
sensory perception of sound GO:0007605 97 0.014
carboxylic acid transport GO:0046942 100 0.013
protein oligomerization GO:0051259 67 0.013
actin filament polymerization GO:0030041 44 0.013
actin filament organization GO:0007015 113 0.013
gtp catabolic process GO:0006184 143 0.013
protein modification by small protein conjugation GO:0032446 187 0.013
regulation of actin cytoskeleton organization GO:0032956 84 0.013
respiratory system development GO:0060541 190 0.013
organic cyclic compound catabolic process GO:1901361 295 0.013
t cell activation GO:0042110 289 0.013
organic anion transport GO:0015711 137 0.013
cellular response to organonitrogen compound GO:0071417 145 0.013
nucleoside triphosphate catabolic process GO:0009143 205 0.013
negative regulation of immune system process GO:0002683 209 0.013
nucleotide metabolic process GO:0009117 332 0.013
gtp metabolic process GO:0046039 144 0.013
inflammatory response GO:0006954 244 0.013
monocarboxylic acid metabolic process GO:0032787 191 0.013
regulation of ras protein signal transduction GO:0046578 114 0.013
regulation of nucleotide metabolic process GO:0006140 169 0.013
negative regulation of phosphate metabolic process GO:0045936 184 0.013
protein ubiquitination GO:0016567 171 0.013
lateral inhibition GO:0046331 1 0.013
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.012
regulation of apoptotic signaling pathway GO:2001233 197 0.012
anatomical structure homeostasis GO:0060249 145 0.012
cytokine production GO:0001816 319 0.012
negative regulation of cell proliferation GO:0008285 296 0.012
lipid modification GO:0030258 65 0.012
intrinsic apoptotic signaling pathway GO:0097193 132 0.012
metal ion homeostasis GO:0055065 189 0.012
sensory perception of mechanical stimulus GO:0050954 107 0.012
regulation of endopeptidase activity GO:0052548 89 0.012
lipid oxidation GO:0034440 29 0.012
heart process GO:0003015 94 0.012
leukocyte differentiation GO:0002521 342 0.012
mesodermal cell migration GO:0008078 4 0.012
regulation of lymphocyte activation GO:0051249 240 0.012
cerebellar granular layer morphogenesis GO:0021683 10 0.012
Mouse
purine ribonucleotide catabolic process GO:0009154 208 0.012
regulation of nucleoside metabolic process GO:0009118 130 0.012
sensory system development GO:0048880 3 0.012
embryonic placenta development GO:0001892 98 0.012
glucose transport GO:0015758 56 0.012
cellular carbohydrate metabolic process GO:0044262 119 0.012
angiogenesis GO:0001525 201 0.012
neuron apoptotic process GO:0051402 142 0.012
sensory perception of pain GO:0019233 47 0.012
positive regulation of mapk cascade GO:0043410 170 0.011
mapk cascade GO:0000165 281 0.011
regulation of purine nucleotide metabolic process GO:1900542 169 0.011
regulation of actin polymerization or depolymerization GO:0008064 45 0.011
regulation of ras gtpase activity GO:0032318 88 0.011
lymphocyte differentiation GO:0030098 242 0.011
fatty acid metabolic process GO:0006631 121 0.011
inorganic cation transmembrane transport GO:0098662 207 0.011
positive regulation of nucleotide metabolic process GO:0045981 114 0.011
actin polymerization or depolymerization GO:0008154 54 0.011
transmission of nerve impulse GO:0019226 76 0.011
regulation of gtp catabolic process GO:0033124 113 0.011
regulation of cell growth GO:0001558 91 0.011
organelle fission GO:0048285 170 0.011
cellular lipid metabolic process GO:0044255 323 0.011
regulation of fatty acid metabolic process GO:0019217 28 0.011
developmental growth involved in morphogenesis GO:0060560 138 0.010
eye photoreceptor cell development GO:0042462 31 0.010
response to drug GO:0042493 75 0.010
cellular response to dna damage stimulus GO:0006974 207 0.010
regulation of cell size GO:0008361 72 0.010
protein modification by small protein conjugation or removal GO:0070647 207 0.010
histone modification GO:0016570 159 0.010
regulation of cytokine production GO:0001817 266 0.010
regulation of nucleotide catabolic process GO:0030811 122 0.010
regulation of cell activation GO:0050865 289 0.010
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.010
oxidation reduction process GO:0055114 342 0.010
lateral line system development GO:0048925 1 0.010
protein polymerization GO:0051258 57 0.010
myeloid cell differentiation GO:0030099 233 0.010
regulation of glucose import GO:0046324 26 0.010

Nrxn2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.020
nervous system disease DOID:863 0 0.020
disease of cellular proliferation DOID:14566 0 0.011